m6A Regulator and Potential Drug Response
General Information of the m6A Regulator (ID: REG00014)
Regulator Name | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) | ||||
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Synonyms |
IGF2 mRNA-binding protein 3; IMP-3; IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer; hKOC; VICKZ family member 3; IMP3; KOC1; VICKZ3
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Gene Name | IGF2BP3 | ||||
Regulator Type | WRITER ERASER READER | ||||
Regulator Link | Click to View Full Information of This Regulator |
Full List of Target Gene(s) of This m6A Regulator and Corresponding Potential Drug Response(s)
Ephrin type-A receptor 2 (EPHA2)
BT5528 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-A receptor 2 (EPHA2) is a therapeutic target for BT5528. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of BT5528 through regulating the expression of Ephrin type-A receptor 2 (EPHA2). | [1], [2] | ||
CAR-T cells targeting EphA2 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-A receptor 2 (EPHA2) is a therapeutic target for CAR-T cells targeting EphA2. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CAR-T cells targeting EphA2 through regulating the expression of Ephrin type-A receptor 2 (EPHA2). | [1], [3] | ||
DS-8895 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-A receptor 2 (EPHA2) is a therapeutic target for DS-8895. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of DS-8895 through regulating the expression of Ephrin type-A receptor 2 (EPHA2). | [1], [4] | ||
MEDI-547 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-A receptor 2 (EPHA2) is a therapeutic target for MEDI-547. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MEDI-547 through regulating the expression of Ephrin type-A receptor 2 (EPHA2). | [1], [5] | ||
MEDI-543 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-A receptor 2 (EPHA2) is a therapeutic target for MEDI-543. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MEDI-543 through regulating the expression of Ephrin type-A receptor 2 (EPHA2). | [1], [6] | ||
AMP-PNP [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-A receptor 2 (EPHA2) is a therapeutic target for AMP-PNP. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of AMP-PNP through regulating the expression of Ephrin type-A receptor 2 (EPHA2). | [1], [7] | ||
Fascin (FSCN1)
NP-G2-044 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fascin (FSCN1) is a therapeutic target for NP-G2-044. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of NP-G2-044 through regulating the expression of Fascin (FSCN1). | [8], [9] | ||
Glucose transporter type 1 (SLC2A1)
D-glucose [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for D-glucose. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of D-glucose through regulating the expression of Glucose transporter type 1 (SLC2A1). | [10], [11] | ||
Quercetin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for Quercetin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Quercetin through regulating the expression of Glucose transporter type 1 (SLC2A1). | [10], [12] | ||
2-Deoxyglucose [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for 2-Deoxyglucose. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 2-Deoxyglucose through regulating the expression of Glucose transporter type 1 (SLC2A1). | [10], [13] | ||
WZB-117 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for WZB-117. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of WZB-117 through regulating the expression of Glucose transporter type 1 (SLC2A1). | [10], [14] | ||
Arsenite [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for Arsenite. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Arsenite through regulating the expression of Glucose transporter type 1 (SLC2A1). | [10], [15] | ||
Dehydroascorbic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for Dehydroascorbic acid. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dehydroascorbic acid through regulating the expression of Glucose transporter type 1 (SLC2A1). | [10], [16] | ||
Hexokinase-2 (HK2)
VDA-1102 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hexokinase-2 (HK2) is a therapeutic target for VDA-1102. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of VDA-1102 through regulating the expression of Hexokinase-2 (HK2). | [10], [17] | ||
Hypoxia-inducible factor 1 alpha (HIF-1A)
HIF-1alpha [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for HIF-1alpha. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of HIF-1alpha through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [19] | ||
IT-101 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for IT-101. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of IT-101 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [20] | ||
2-Methoxyestradiol [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for 2-Methoxyestradiol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 2-Methoxyestradiol through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [21] | ||
PT2385 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for PT2385. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of PT2385 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [22] | ||
ENMD-1198 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ENMD-1198. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ENMD-1198 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [23] | ||
EZN-2968 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for EZN-2968. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of EZN-2968 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [24] | ||
PX-478 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for PX-478. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of PX-478 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [25] | ||
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for (5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of (5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [26] | ||
ISIS 175510 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 175510. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 175510 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298697 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298697. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298697 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298699 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298699. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298699 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298700 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298700. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298700 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298701 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298701. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298701 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298702 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298702. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298702 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298711 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298711. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298711 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298712 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298712. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298712 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298743 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298743. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298743 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298744 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298744. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298744 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298745 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298745. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298745 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [27] | ||
ISIS 298746 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Hypoxia-inducible factor 1 alpha (HIF-1A) is a therapeutic target for ISIS 298746. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ISIS 298746 through regulating the expression of Hypoxia-inducible factor 1 alpha (HIF-1A). | [18], [28] | ||
P-glycoprotein 1 (ABCB1)
Abacavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Abacavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Abacavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [30] | ||
Acebutolol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Acebutolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Acebutolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Acrivastine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Acrivastine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Acrivastine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Actinomycin D [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Actinomycin D. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Actinomycin D through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Afatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Afatinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Afatinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [34] | ||
Ajmaline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ajmaline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ajmaline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [35] | ||
Albendazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Albendazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Albendazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [36] | ||
Aldosterone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Aldosterone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Aldosterone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [37] | ||
Aliskiren fumarate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Aliskiren fumarate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Aliskiren fumarate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [38] | ||
Ambrisentan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ambrisentan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ambrisentan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [39] | ||
Amiodarone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Amiodarone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Amiodarone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Amisulpride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Amisulpride. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Amisulpride through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Amitriptyline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Amitriptyline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Amitriptyline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [41] | ||
Amoxicillin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Amoxicillin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Amoxicillin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Amphotericin B [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Amphotericin B. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Amphotericin B through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [42] | ||
Amprenavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Amprenavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Amprenavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Apixaban [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Apixaban. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Apixaban through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [43] | ||
Apremilast [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Apremilast. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Apremilast through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Aprepitant [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Aprepitant. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Aprepitant through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Arsenic trioxide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Arsenic trioxide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Arsenic trioxide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [46] | ||
Aspirin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Aspirin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Aspirin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [41] | ||
Atenolol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Atenolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Atenolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [47] | ||
Atomoxetine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Atomoxetine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Atomoxetine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Axitinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Axitinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Axitinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [48] | ||
Azasetron [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Azasetron. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Azasetron through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Azathioprine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Azathioprine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Azathioprine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [41] | ||
Azithromycin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Azithromycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Azithromycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [49] | ||
Baloxavir marboxil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Baloxavir marboxil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Baloxavir marboxil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [50] | ||
Baricitinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Baricitinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Baricitinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [51] | ||
Beclomethasone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Beclomethasone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Beclomethasone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [52] | ||
Beclomethasone dipropionate [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Beclomethasone dipropionate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Beclomethasone dipropionate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [52] | ||
Bepridil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bepridil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bepridil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
beta-Acetyldigoxin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for beta-Acetyldigoxin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of beta-Acetyldigoxin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [53] | ||
beta-Carotene [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for beta-Carotene. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of beta-Carotene through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [42] | ||
Betamethasone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Betamethasone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Betamethasone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [54] | ||
Betrixaban [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Betrixaban. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Betrixaban through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [55] | ||
Bicalutamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bicalutamide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bicalutamide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [56] | ||
Binimetinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Binimetinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Binimetinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [57] | ||
Biotin [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Biotin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Biotin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [58] | ||
Boceprevir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Boceprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Boceprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [59] | ||
Bosutinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bosutinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bosutinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [60] | ||
Brilinta [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Brilinta. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Brilinta through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Bromocriptine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bromocriptine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bromocriptine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Bupropion [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bupropion. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bupropion through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [62] | ||
Cabergoline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cabergoline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cabergoline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [63] | ||
Canagliflozin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Canagliflozin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Canagliflozin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [64] | ||
Cannabidiol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cannabidiol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cannabidiol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Carfilzomib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Carfilzomib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Carfilzomib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [65] | ||
Carvedilol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Carvedilol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Carvedilol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Cefoperazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cefoperazone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cefoperazone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Cefotetan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cefotetan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cefotetan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Ceftriaxone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ceftriaxone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ceftriaxone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Celiprolol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Celiprolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Celiprolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [66] | ||
Cepharanthine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cepharanthine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cepharanthine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [67] | ||
Ceritinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ceritinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ceritinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [68] | ||
Cerivastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cerivastatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cerivastatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [69] | ||
Cetirizine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cetirizine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cetirizine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [70] | ||
Chlorambucil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Chlorambucil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Chlorambucil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Chloramphenicol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Chloramphenicol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Chloramphenicol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [71] | ||
Chlorpromazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Chlorpromazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Chlorpromazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ciclesonide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ciclesonide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ciclesonide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [52] | ||
Cimetidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cimetidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cimetidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Cinchonidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cinchonidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cinchonidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Cisplatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cisplatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cisplatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Citalopram [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Citalopram. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Citalopram through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [72] | ||
Clarithromycin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clarithromycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clarithromycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Clobazam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clobazam. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clobazam through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Clofazimine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clofazimine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clofazimine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [73] | ||
Clomifene [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clomifene. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clomifene through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Clomiphene citrate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clomiphene citrate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clomiphene citrate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Clomipramine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clomipramine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clomipramine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Clonidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clonidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clonidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [41] | ||
Clopidogrel [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clopidogrel. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clopidogrel through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [75] | ||
Clozapine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Clozapine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Clozapine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Colchicine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Colchicine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Colchicine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [76] | ||
Cortisone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cortisone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cortisone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [54] | ||
Cyclosporine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cyclosporine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cyclosporine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [77] | ||
Cytarabine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cytarabine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cytarabine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Dabigatran [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dabigatran. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dabigatran through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [78] | ||
Dabrafenib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dabrafenib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dabrafenib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [79] | ||
Daclatasvir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Daclatasvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Daclatasvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [78] | ||
Dactinomycin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dactinomycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dactinomycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [80] | ||
Darunavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Darunavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Darunavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [81] | ||
Debrisoquine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Debrisoquine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Debrisoquine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [82] | ||
Deflazacort [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Deflazacort. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Deflazacort through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Delavirdine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Delavirdine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Delavirdine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [30] | ||
Desipramine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Desipramine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Desipramine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Desloratadine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Desloratadine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Desloratadine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [84] | ||
Diazepam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Diazepam. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Diazepam through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [85] | ||
Dicloxacillin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dicloxacillin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dicloxacillin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [86] | ||
Diethylstilbestrol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Diethylstilbestrol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Diethylstilbestrol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Digitoxin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Digitoxin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Digitoxin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [87] | ||
Digoxin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Digoxin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Digoxin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [88] | ||
Dihydroergocristine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dihydroergocristine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dihydroergocristine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [89] | ||
Diltiazem [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Diltiazem. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Diltiazem through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Dipyridamole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dipyridamole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dipyridamole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Docetaxel [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Docetaxel. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Docetaxel through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [90] | ||
Dolutegravir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dolutegravir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dolutegravir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Domperidone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Domperidone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Domperidone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Doxycycline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Doxycycline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Doxycycline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ebastine [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ebastine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ebastine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Edoxaban [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Edoxaban. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Edoxaban through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [91] | ||
Efavirenz [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Efavirenz. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Efavirenz through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Eletriptan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Eletriptan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Eletriptan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Eliglustat tartrate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Eliglustat tartrate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Eliglustat tartrate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Emetine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Emetine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Emetine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [80] | ||
Empagliflozin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Empagliflozin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Empagliflozin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Epinastine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Epinastine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Epinastine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [92] | ||
Epirubicin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Epirubicin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Epirubicin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ergotamine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ergotamine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ergotamine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Erythromycin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Erythromycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Erythromycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [93] | ||
Eslicarbazepine acetate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Eslicarbazepine acetate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Eslicarbazepine acetate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [94] | ||
Estradiol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Estradiol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Estradiol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Estriol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Estriol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Estriol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [95] | ||
Estrone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Estrone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Estrone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [95] | ||
Estrone sulfate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Estrone sulfate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Estrone sulfate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [69] | ||
Ethinyl estradiol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ethinyl estradiol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ethinyl estradiol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [95] | ||
Etoposide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Etoposide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Etoposide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [96] | ||
Ezetimibe [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ezetimibe. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ezetimibe through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [97] | ||
Famciclovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Famciclovir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Famciclovir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Felodipine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Felodipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Felodipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [98] | ||
Fentanyl [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fentanyl. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fentanyl through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Fesoterodine fumarate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fesoterodine fumarate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fesoterodine fumarate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [99] | ||
Fexofenadine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fexofenadine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fexofenadine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [100] | ||
Fluoxetine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fluoxetine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fluoxetine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [101] | ||
Flupentixol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Flupentixol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Flupentixol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Fluphenazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fluphenazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fluphenazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Fluticasone propionate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fluticasone propionate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fluticasone propionate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [52] | ||
Fluvastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fluvastatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fluvastatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Fluvoxamine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fluvoxamine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fluvoxamine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Folic acid [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Folic acid. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Folic acid through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [102] | ||
Fosamprenavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fosamprenavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fosamprenavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Gatifloxacin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Gatifloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Gatifloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [103] | ||
Gilteritinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Gilteritinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Gilteritinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Glutathione [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Glutathione. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Glutathione through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [104] | ||
Gramicidin D [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Gramicidin D. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Gramicidin D through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Grepafloxacin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Grepafloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Grepafloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Guanabenz [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Guanabenz. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Guanabenz through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Guanfacine [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Guanfacine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Guanfacine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [105] | ||
Haloperidol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Haloperidol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Haloperidol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Hydrocortisone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Hydrocortisone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Hydrocortisone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [52] | ||
Hydroxyurea [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Hydroxyurea. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Hydroxyurea through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ibrutinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ibrutinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ibrutinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [106] | ||
Idarubicin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Idarubicin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Idarubicin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [107] | ||
Imatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Imatinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Imatinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [108] | ||
Imipramine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Imipramine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Imipramine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [41] | ||
Indacaterol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Indacaterol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Indacaterol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Indinavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Indinavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Indinavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [109] | ||
Indomethacin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Indomethacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Indomethacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [110] | ||
Ingenol-3-angelate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ingenol-3-angelate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ingenol-3-angelate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [111] | ||
Irinotecan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Irinotecan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Irinotecan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [112] | ||
Itraconazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Itraconazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Itraconazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ivacaftor [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ivacaftor. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ivacaftor through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [113] | ||
Ivermectin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ivermectin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ivermectin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [114] | ||
Ivosidenib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ivosidenib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ivosidenib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [115] | ||
Ixabepilone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ixabepilone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ixabepilone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [116] | ||
Ketoconazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ketoconazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ketoconazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
L-tryptophan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for L-tryptophan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of L-tryptophan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [117] | ||
Labetalol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Labetalol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Labetalol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Lamotrigine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lamotrigine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lamotrigine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [118] | ||
Lansoprazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lansoprazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lansoprazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Lapatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lapatinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lapatinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Ledipasvir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ledipasvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ledipasvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Lenalidomide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lenalidomide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lenalidomide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [119] | ||
Lenvatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lenvatinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lenvatinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [120] | ||
Levetiracetam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Levetiracetam. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Levetiracetam through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [121] | ||
Levodopa [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Levodopa. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Levodopa through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Levofloxacin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Levofloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Levofloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Levomepromazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Levomepromazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Levomepromazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Levomilnacipran [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Levomilnacipran. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Levomilnacipran through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [122] | ||
Lidocaine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lidocaine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lidocaine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Linagliptin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Linagliptin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Linagliptin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Loperamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Loperamide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Loperamide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [123] | ||
Lopinavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lopinavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lopinavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [124] | ||
Loratadine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Loratadine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Loratadine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [84] | ||
Losartan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Losartan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Losartan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [125] | ||
Lovastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lovastatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lovastatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Lovastatin acid [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Lovastatin acid. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Lovastatin acid through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Maraviroc [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Maraviroc. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Maraviroc through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Mefloquine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mefloquine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mefloquine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [126] | ||
Melphalan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Melphalan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Melphalan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [127] | ||
Meperidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Meperidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Meperidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [128] | ||
Mequitazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mequitazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mequitazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Methadone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Methadone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Methadone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [129] | ||
Methotrexate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Methotrexate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Methotrexate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Methylprednisolone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Methylprednisolone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Methylprednisolone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [130] | ||
Methysergide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Methysergide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Methysergide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Midazolam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Midazolam. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Midazolam through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Midostaurin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Midostaurin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Midostaurin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Mitomycin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mitomycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mitomycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [131] | ||
Mitoxantrone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mitoxantrone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mitoxantrone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Morphine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Morphine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Morphine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [132] | ||
Moxidectin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Moxidectin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Moxidectin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [133] | ||
Mycophenolate mofetil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mycophenolate mofetil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mycophenolate mofetil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [134] | ||
Nadolol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nadolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nadolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Nalbuphine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nalbuphine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nalbuphine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Naloxegol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Naloxegol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Naloxegol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Nelfinavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nelfinavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nelfinavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [135] | ||
Neostigmine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Neostigmine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Neostigmine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Nevirapine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nevirapine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nevirapine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Nicardipine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nicardipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nicardipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [136] | ||
Nifedipine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nifedipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nifedipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Nilotinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nilotinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nilotinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Nimodipine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nimodipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nimodipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Nintedanib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nintedanib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nintedanib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [137] | ||
Nisoldipine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nisoldipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nisoldipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Nitrendipine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nitrendipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nitrendipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Nizatidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nizatidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nizatidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [138] | ||
Norfloxacin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Norfloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Norfloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Olanzapine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Olanzapine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Olanzapine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Olmesartan medoxomil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Olmesartan medoxomil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Olmesartan medoxomil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Olopatadine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Olopatadine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Olopatadine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Omadacycline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Omadacycline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Omadacycline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [139] | ||
Ombitasvir [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ombitasvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ombitasvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Omeprazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Omeprazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Omeprazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Ondansetron [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ondansetron. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ondansetron through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [126] | ||
Oseltamivir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Oseltamivir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Oseltamivir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [140] | ||
Oxcarbazepine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Oxcarbazepine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Oxcarbazepine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [141] | ||
Palbociclib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Palbociclib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Palbociclib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [142] | ||
Paliperidone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Paliperidone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Paliperidone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [143] | ||
Panobinostat [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Panobinostat. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Panobinostat through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [144] | ||
Pantoprazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pantoprazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pantoprazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Paroxetine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Paroxetine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Paroxetine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Pazopanib hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pazopanib hydrochloride. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pazopanib hydrochloride through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [145] | ||
Pemirolast [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pemirolast. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pemirolast through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Pentazocine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pentazocine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pentazocine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Perazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Perazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Perazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Perphenazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Perphenazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Perphenazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Phenobarbital [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Phenobarbital. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Phenobarbital through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [141] | ||
Phenprocoumon [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Phenprocoumon. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Phenprocoumon through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [146] | ||
Phenytoin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Phenytoin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Phenytoin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [141] | ||
Pibrentasvir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pibrentasvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pibrentasvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Pimozide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pimozide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pimozide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Pirarubicin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pirarubicin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pirarubicin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Pirenzepine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pirenzepine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pirenzepine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Pomalidomide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pomalidomide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pomalidomide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [147] | ||
Ponatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ponatinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ponatinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [148] | ||
Posaconazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Posaconazole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Posaconazole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Pravastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pravastatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pravastatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Prazosin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Prazosin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Prazosin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [149] | ||
Prednisolone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Prednisolone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Prednisolone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [150] | ||
Prednisone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Prednisone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Prednisone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [54] | ||
Progesterone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Progesterone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Progesterone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [85] | ||
Propafenone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Propafenone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Propafenone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Propranolol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Propranolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Propranolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Protriptyline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Protriptyline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Protriptyline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [32] | ||
Prucalopride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Prucalopride. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Prucalopride through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [151] | ||
Quercetin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Quercetin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Quercetin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [152] | ||
Quetiapine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Quetiapine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Quetiapine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [40] | ||
Quinine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Quinine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Quinine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Raloxifene [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Raloxifene. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Raloxifene through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [153] | ||
Ramosetron [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ramosetron. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ramosetron through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [154] | ||
Ranitidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ranitidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ranitidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ranolazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ranolazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ranolazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [155] | ||
Regorafenib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Regorafenib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Regorafenib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [156] | ||
Reserpine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Reserpine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Reserpine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Rifampicin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Rifampicin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Rifampicin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Rifaximin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Rifaximin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Rifaximin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [157] | ||
Riociguat [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Riociguat. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Riociguat through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [158] | ||
Risperidone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Risperidone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Risperidone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [159] | ||
Ritonavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ritonavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ritonavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [160] | ||
Rivaroxaban [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Rivaroxaban. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Rivaroxaban through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [161] | ||
Romidepsin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Romidepsin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Romidepsin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [162] | ||
Rosuvastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Rosuvastatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Rosuvastatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [163] | ||
S-licarbazepine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for S-licarbazepine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of S-licarbazepine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [94] | ||
Saphris [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Saphris. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Saphris through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Saquinavir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Saquinavir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Saquinavir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [164] | ||
Saxagliptin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Saxagliptin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Saxagliptin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Sertraline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sertraline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sertraline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Silodosin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Silodosin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Silodosin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [165] | ||
Simeprevir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Simeprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Simeprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Simvastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Simvastatin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Simvastatin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Sitagliptin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sitagliptin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sitagliptin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Sofosbuvir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sofosbuvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sofosbuvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [166] | ||
Sparfloxacin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sparfloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sparfloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Spiperone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Spiperone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Spiperone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Sumatriptan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sumatriptan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sumatriptan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [167] | ||
Sunitinib malate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sunitinib malate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sunitinib malate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [168] | ||
Tacrine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tacrine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tacrine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [169] | ||
Tacrolimus [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tacrolimus. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tacrolimus through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Tadalafil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tadalafil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tadalafil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [170] | ||
Talazoparib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Talazoparib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Talazoparib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [171] | ||
Telaprevir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Telaprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Telaprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [59] | ||
Telithromycin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Telithromycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Telithromycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [172] | ||
Temsirolimus [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Temsirolimus. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Temsirolimus through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [173] | ||
Tenofovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tenofovir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tenofovir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Tenofovir disoproxil [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tenofovir disoproxil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tenofovir disoproxil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Tenoxicam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tenoxicam. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tenoxicam through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Testosterone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Testosterone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Testosterone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Tetracycline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tetracycline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tetracycline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Thiamphenicol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Thiamphenicol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Thiamphenicol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [71] | ||
Thioridazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Thioridazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Thioridazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Timolol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Timolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Timolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [66] | ||
Tolvaptan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tolvaptan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tolvaptan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [174] | ||
Topiramate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Topiramate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Topiramate through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [175] | ||
Topotecan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Topotecan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Topotecan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [176] | ||
Toremifene [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Toremifene. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Toremifene through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Tramadol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tramadol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tramadol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [177] | ||
Trifluoperazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Trifluoperazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Trifluoperazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Triflupromazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Triflupromazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Triflupromazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Trimethoprim [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Trimethoprim. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Trimethoprim through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Triprolidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Triprolidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Triprolidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [178] | ||
Trospium chloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Trospium chloride. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Trospium chloride through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [179] | ||
Vecuronium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Vecuronium. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Vecuronium through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [126] | ||
Venetoclax [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Venetoclax. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Venetoclax through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [180] | ||
Verapamil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Verapamil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Verapamil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [181] | ||
vildagliptin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for vildagliptin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of vildagliptin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [182] | ||
Vinblastine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Vinblastine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Vinblastine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [183] | ||
Vincristine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Vincristine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Vincristine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [184] | ||
Vindesine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Vindesine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Vindesine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Vinorelbine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Vinorelbine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Vinorelbine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [185] | ||
Zidovudine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Zidovudine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Zidovudine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [30] | ||
Ziprasidone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ziprasidone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ziprasidone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Zolmitriptan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Zolmitriptan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Zolmitriptan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
4-Hydroxytamoxifen [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for 4-Hydroxytamoxifen. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 4-Hydroxytamoxifen through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Asimadoline [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Asimadoline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Asimadoline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Asunaprevir [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Asunaprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Asunaprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Belotecan [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Belotecan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Belotecan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
CBT-1 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for CBT-1. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CBT-1 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [186] | ||
Corticosterone [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Corticosterone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Corticosterone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Dasabuvir [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dasabuvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dasabuvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Morphine-6-glucuronide [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Morphine-6-glucuronide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Morphine-6-glucuronide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Pazufloxacin [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pazufloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pazufloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [187] | ||
Relugolix [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Relugolix. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Relugolix through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Simvastatin acid [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Simvastatin acid. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Simvastatin acid through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [188] | ||
Sitafloxacin [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Sitafloxacin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sitafloxacin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Tenofovir alafenamide [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tenofovir alafenamide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tenofovir alafenamide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [189] | ||
Vibegron [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Vibegron. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Vibegron through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
(Z)-endoxifen [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for (Z)-endoxifen. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of (Z)-endoxifen through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [190] | ||
ABT-263 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for ABT-263. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ABT-263 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [191] | ||
Bisantrene [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bisantrene. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bisantrene through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Cholesterol [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cholesterol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cholesterol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [192] | ||
CP-122721 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for CP-122721. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CP-122721 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [193] | ||
Curcumin [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Curcumin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Curcumin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Dihydrotestosterone [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dihydrotestosterone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dihydrotestosterone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [194] | ||
Dolastatin 10 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dolastatin 10. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dolastatin 10 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [195] | ||
Fucoxanthin [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Fucoxanthin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Fucoxanthin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [42] | ||
Gallopamil [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Gallopamil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Gallopamil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Gepirone [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Gepirone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Gepirone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Glecaprevir [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Glecaprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Glecaprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Norverapamil [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Norverapamil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Norverapamil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [196] | ||
NSC325663 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for NSC325663. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of NSC325663 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
Paritaprevir [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Paritaprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Paritaprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Roscovitine [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Roscovitine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Roscovitine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [198] | ||
Staurosporine [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Staurosporine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Staurosporine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
EDP-322 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for EDP-322. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of EDP-322 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [199] | ||
Genz 644282 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Genz 644282. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Genz 644282 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [200] | ||
Naringenin [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Naringenin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Naringenin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [152] | ||
Norbuprenorphine [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Norbuprenorphine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Norbuprenorphine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [201] | ||
Prostaglandin A2 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Prostaglandin A2. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Prostaglandin A2 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [202] | ||
Substance P [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Substance P. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Substance P through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [203] | ||
Talinolol [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Talinolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Talinolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [204] | ||
Velpatasvir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Velpatasvir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Velpatasvir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
Voxilaprevir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Voxilaprevir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Voxilaprevir through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [44] | ||
W-198 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for W-198. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of W-198 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [205] | ||
YP-005 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for YP-005. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of YP-005 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [206] | ||
Abamectin B1A [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Abamectin B1A. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Abamectin B1A through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [207] | ||
AG1478 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for AG1478. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of AG1478 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [208] | ||
Bouvardin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bouvardin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bouvardin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
Bunitrolol [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bunitrolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bunitrolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [209] | ||
Cephaeline [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cephaeline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cephaeline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
Coelenterazine [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Coelenterazine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Coelenterazine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [210] | ||
Cycloheximide [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Cycloheximide. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cycloheximide through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [42] | ||
Desmethylsertraline [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Desmethylsertraline. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Desmethylsertraline through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [62] | ||
E-guggulsterone [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for E-guggulsterone. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of E-guggulsterone through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [211] | ||
Epothilone A [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Epothilone A. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Epothilone A through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Geneticin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Geneticin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Geneticin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [212] | ||
Metildigoxin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Metildigoxin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Metildigoxin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [61] | ||
Metkephamid [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Metkephamid. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Metkephamid through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
MG-132 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for MG-132. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MG-132 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [213] | ||
N-desethyl sunitinib [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for N-desethyl sunitinib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of N-desethyl sunitinib through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [214] | ||
Nafoxidine [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nafoxidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nafoxidine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [74] | ||
Nogalamycin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nogalamycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nogalamycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
Nonactin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Nonactin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Nonactin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [80] | ||
Okadaic acid [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Okadaic acid. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Okadaic acid through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
Pepstatin A [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pepstatin A. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pepstatin A through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Puromycin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Puromycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Puromycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [212] | ||
Selamectin [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Selamectin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Selamectin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [207] | ||
Silvestrol [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Silvestrol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Silvestrol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [215] | ||
SNS-032 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for SNS-032. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of SNS-032 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
4,3'',5''-trimethoxy-[1,1':2',1'']-terphenyl [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for 4,3'',5''-trimethoxy-[1,1':2',1'']-terphenyl. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 4,3'',5''-trimethoxy-[1,1':2',1'']-terphenyl through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [216] | ||
6-(3,5-dimethoxy-phenyl)-naphthalen-2-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for 6-(3,5-dimethoxy-phenyl)-naphthalen-2-ol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 6-(3,5-dimethoxy-phenyl)-naphthalen-2-ol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [217] | ||
Azidopine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Azidopine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Azidopine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Bcecf-Am [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Bcecf-Am. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bcecf-Am through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Hoechst 33342 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Hoechst 33342. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Hoechst 33342 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Leupeptin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Leupeptin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Leupeptin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Paraquat [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Paraquat. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Paraquat through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Tiapamil [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tiapamil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tiapamil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
TRISMETHOXYRESVERATROL [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for TRISMETHOXYRESVERATROL. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of TRISMETHOXYRESVERATROL through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [216] | ||
Valinomycin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Valinomycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Valinomycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [136] | ||
XR-9456 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for XR-9456. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of XR-9456 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [217] | ||
XR-9504 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for XR-9504. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of XR-9504 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [217] | ||
XR-9544 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for XR-9544. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of XR-9544 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [218] | ||
XR-9577 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for XR-9577. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of XR-9577 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [217] | ||
[1,1':2',1'']-terphenyl-4,3'',5''-triol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for [1,1':2',1'']-terphenyl-4,3'',5''-triol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of [1,1':2',1'']-terphenyl-4,3'',5''-triol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [216] | ||
ABT-737 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for ABT-737. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ABT-737 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [191] | ||
Alprenolol [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Alprenolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Alprenolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Apafant [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Apafant. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Apafant through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [219] | ||
Astemizole [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Astemizole. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Astemizole through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [45] | ||
Biricodar [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Biricodar. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Biricodar through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [216] | ||
Calphostin C [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Calphostin C. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Calphostin C through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Dexniguldipine [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Dexniguldipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Dexniguldipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [197] | ||
Droloxifene [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Droloxifene. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Droloxifene through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
ELACRIDAR [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for ELACRIDAR. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ELACRIDAR through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [220] | ||
Flesinoxan [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Flesinoxan. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Flesinoxan through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [221] | ||
Hydroxybupropion [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Hydroxybupropion. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Hydroxybupropion through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [62] | ||
Isoxicam [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Isoxicam. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Isoxicam through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
LY335979 [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for LY335979. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of LY335979 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [222] | ||
Melagatran [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Melagatran. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Melagatran through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Mibefradil [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mibefradil. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mibefradil through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Mithramycin [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Mithramycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Mithramycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Niguldipine [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Niguldipine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Niguldipine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
ONT-093 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for ONT-093. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ONT-093 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [223] | ||
Pafenolol [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Pafenolol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pafenolol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Rhodamine 123 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Rhodamine 123. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Rhodamine 123 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [136] | ||
Roxithromycin [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Roxithromycin. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Roxithromycin through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [172] | ||
S9788 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for S9788. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of S9788 through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Tariquidar [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tariquidar. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tariquidar through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [224] | ||
Terfenadine [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Terfenadine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Terfenadine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Tolafentrine [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Tolafentrine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Tolafentrine through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [83] | ||
Trans-flupentixol [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Trans-flupentixol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Trans-flupentixol through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Valspodar [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Valspodar. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Valspodar through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [33] | ||
Ximelagatran [Withdrawn]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | P-glycoprotein 1 (ABCB1) is a therapeutic target for Ximelagatran. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ximelagatran through regulating the expression of P-glycoprotein 1 (ABCB1). | [29], [31] | ||
Programmed cell death 1 ligand 1 (PD-L1)
Atezolizumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Atezolizumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Atezolizumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [226] | ||
Avelumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Avelumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Avelumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [227] | ||
Bavencio [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Bavencio. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bavencio through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [228] | ||
Durvalumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Durvalumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Durvalumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [229] | ||
RG-7446 [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for RG-7446. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of RG-7446 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [230] | ||
CS1001 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CS1001. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CS1001 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [231] | ||
KN046 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for KN046. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of KN046 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [232] | ||
MEDI4736 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MEDI4736. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MEDI4736 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [233] | ||
MPDL-3280A [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MPDL-3280A. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MPDL-3280A through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [234] | ||
BGB-A333 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for BGB-A333. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of BGB-A333 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [235] | ||
Bintrafusp alfa [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Bintrafusp alfa. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bintrafusp alfa through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [236] | ||
CX-072 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CX-072. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CX-072 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [237] | ||
GS-4224 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for GS-4224. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of GS-4224 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [238] | ||
INCB86550 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for INCB86550. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of INCB86550 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [239] | ||
KN035 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for KN035. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of KN035 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [240] | ||
M7824 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for M7824. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of M7824 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [241] | ||
NM21-1480 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for NM21-1480. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of NM21-1480 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [229] | ||
Pidilizumab [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Pidilizumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Pidilizumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [26], [225] | ||
ALPN-202 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for ALPN-202. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ALPN-202 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [242] | ||
Anti-PD-L1 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Anti-PD-L1. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Anti-PD-L1 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [243] | ||
Anti-PD-L1 CSR T cells [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Anti-PD-L1 CSR T cells. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Anti-PD-L1 CSR T cells through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [26], [225] | ||
BMS-986189 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for BMS-986189. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of BMS-986189 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [229] | ||
CA-170 [Phase 1]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CA-170. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CA-170 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [241] | ||
Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CA-170. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CA-170 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [244] | |||
Cosibelimab [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Cosibelimab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Cosibelimab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [245] | ||
FAZ053 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for FAZ053. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of FAZ053 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [229] | ||
FS118 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for FS118. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of FS118 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [246] | ||
GEN1046 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for GEN1046. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of GEN1046 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [247] | ||
IBI318 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for IBI318. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of IBI318 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [248] | ||
INBRX-105 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for INBRX-105. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of INBRX-105 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [249] | ||
KD033 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for KD033. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of KD033 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [250] | ||
LY3300054 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for LY3300054. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of LY3300054 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [26], [225] | ||
LY3415244 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for LY3415244. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of LY3415244 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [251] | ||
MCLA-145 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MCLA-145. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MCLA-145 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [252] | ||
MSB2311 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MSB2311. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MSB2311 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [229] | ||
PD-L1 t-haNK [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for PD-L1 t-haNK. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of PD-L1 t-haNK through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [253] | ||
RG6084 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for RG6084. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of RG6084 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [241] | ||
TAK-252 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for TAK-252. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of TAK-252 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [254] | ||
CA-327 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CA-327. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of CA-327 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [225], [229] | ||
Proto-oncogene c-Myc (MYC)
AVI-5126 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Proto-oncogene c-Myc (MYC) is a therapeutic target for AVI-5126. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of AVI-5126 through regulating the expression of Proto-oncogene c-Myc (MYC). | [255], [256] | ||
Resten-NG [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Proto-oncogene c-Myc (MYC) is a therapeutic target for Resten-NG. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Resten-NG through regulating the expression of Proto-oncogene c-Myc (MYC). | [255], [257] | ||
TWS-119 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Proto-oncogene c-Myc (MYC) is a therapeutic target for TWS-119. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of TWS-119 through regulating the expression of Proto-oncogene c-Myc (MYC). | [255], [258] | ||
Thymidine kinase 1 (TK1)
DEOXYCYTIDINE [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for DEOXYCYTIDINE. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of DEOXYCYTIDINE through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
Penciclovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Penciclovir. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Penciclovir through regulating the expression of Thymidine kinase 1 (TK1). | [8], [260] | ||
TK-DLI [Preregistration]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for TK-DLI. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of TK-DLI through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
FV-100 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for FV-100. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of FV-100 through regulating the expression of Thymidine kinase 1 (TK1). | [8], [261] | ||
Radiosensitizer gene therapy [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Radiosensitizer gene therapy. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Radiosensitizer gene therapy through regulating the expression of Thymidine kinase 1 (TK1). | [8], [262] | ||
RP101 [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for RP101. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of RP101 through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
HQK-1004 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for HQK-1004. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of HQK-1004 through regulating the expression of Thymidine kinase 1 (TK1). | [8], [263] | ||
Rilapladib [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Rilapladib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Rilapladib through regulating the expression of Thymidine kinase 1 (TK1). | [8], [264] | ||
Thymidine kinase-expressing adenovirus and ganciclovir suicide gene therapy [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Thymidine kinase-expressing adenovirus and ganciclovir suicide gene therapy. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Thymidine kinase-expressing adenovirus and ganciclovir suicide gene therapy through regulating the expression of Thymidine kinase 1 (TK1). | [8], [265] | ||
(South)-Methanocarba-Thymidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for (South)-Methanocarba-Thymidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of (South)-Methanocarba-Thymidine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [266] | ||
1-[2-(2-triphenylmethoxyethoxy)ethyl]thymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 1-[2-(2-triphenylmethoxyethoxy)ethyl]thymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 1-[2-(2-triphenylmethoxyethoxy)ethyl]thymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [266] | ||
1-[5-(triphenylmethoxy)pentyl]thymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 1-[5-(triphenylmethoxy)pentyl]thymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 1-[5-(triphenylmethoxy)pentyl]thymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [266] | ||
1-[6-(triphenylmethoxy)hexyl]thymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 1-[6-(triphenylmethoxy)hexyl]thymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 1-[6-(triphenylmethoxy)hexyl]thymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [266] | ||
1-[7-(triphenylmethoxy)heptyl]thymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 1-[7-(triphenylmethoxy)heptyl]thymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 1-[7-(triphenylmethoxy)heptyl]thymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [267] | ||
2'-deoxythymidine triphosphate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 2'-deoxythymidine triphosphate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 2'-deoxythymidine triphosphate through regulating the expression of Thymidine kinase 1 (TK1). | [8], [264] | ||
2'-Deoxyuridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 2'-Deoxyuridine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 2'-Deoxyuridine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [268] | ||
3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [260] | ||
3-(2-propyn-1-yl)thymidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 3-(2-propyn-1-yl)thymidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 3-(2-propyn-1-yl)thymidine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [269] | ||
5-Bromothienyldeoxyuridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 5-Bromothienyldeoxyuridine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 5-Bromothienyldeoxyuridine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
5-Iodo-2'-Deoxyuridine-5'-Monophosphate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 5-Iodo-2'-Deoxyuridine-5'-Monophosphate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 5-Iodo-2'-Deoxyuridine-5'-Monophosphate through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
5-propyl-2'-deoxyuridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 5-propyl-2'-deoxyuridine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 5-propyl-2'-deoxyuridine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [269] | ||
6-(Dihydroxy-Isobutyl)-Thymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 6-(Dihydroxy-Isobutyl)-Thymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 6-(Dihydroxy-Isobutyl)-Thymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
6-Hydroxypropylthymine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 6-Hydroxypropylthymine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 6-Hydroxypropylthymine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [270] | ||
9-(4-Hydroxybutyl)-N2-Phenylguanine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 9-(4-Hydroxybutyl)-N2-Phenylguanine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 9-(4-Hydroxybutyl)-N2-Phenylguanine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
9-Hydroxypropyladenine, R-Isomer [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 9-Hydroxypropyladenine, R-Isomer. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 9-Hydroxypropyladenine, R-Isomer through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
9-Hydroxypropyladenine, S-Isomer [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for 9-Hydroxypropyladenine, S-Isomer. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of 9-Hydroxypropyladenine, S-Isomer through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
BVDU-MP [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for BVDU-MP. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of BVDU-MP through regulating the expression of Thymidine kinase 1 (TK1). | [8], [271] | ||
Deoxythymidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Deoxythymidine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Deoxythymidine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
Edoxudine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Edoxudine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Edoxudine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [269] | ||
ITdU [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for ITdU. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ITdU through regulating the expression of Thymidine kinase 1 (TK1). | [8], [266] | ||
L-5-(bromovinyl)deoxyuridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for L-5-(bromovinyl)deoxyuridine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of L-5-(bromovinyl)deoxyuridine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [272] | ||
L-5-iodo-2'-deoxyuridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for L-5-iodo-2'-deoxyuridine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of L-5-iodo-2'-deoxyuridine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [269] | ||
N2-(3-trifluoromethylphenyl)guanine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for N2-(3-trifluoromethylphenyl)guanine. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of N2-(3-trifluoromethylphenyl)guanine through regulating the expression of Thymidine kinase 1 (TK1). | [8], [269] | ||
P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
Thymidine-5'-Phosphate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Thymidine-5'-Phosphate. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Thymidine-5'-Phosphate through regulating the expression of Thymidine kinase 1 (TK1). | [8], [259] | ||
Sitimagene ceradenovec [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Thymidine kinase 1 (TK1) is a therapeutic target for Sitimagene ceradenovec. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Sitimagene ceradenovec through regulating the expression of Thymidine kinase 1 (TK1). | [8], [273] | ||
Vascular endothelial growth factor A (VEGFA)
Aflibercept [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Aflibercept. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Aflibercept through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [274] | ||
Bevacizumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Bevacizumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bevacizumab through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [275] | ||
Brolucizumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Brolucizumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Brolucizumab through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [276] | ||
Ranibizumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Ranibizumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Ranibizumab through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [277] | ||
Faricimab [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Faricimab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Faricimab through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [278] | ||
Abicipar pegol [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Abicipar pegol. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Abicipar pegol through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [279] | ||
MP0250 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for MP0250. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MP0250 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [280] | ||
PTC299 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for PTC299. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of PTC299 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [281] | ||
RG7221 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for RG7221. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of RG7221 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [282] | ||
RO5520985 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for RO5520985. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of RO5520985 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [283] | ||
SNN-0029 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for SNN-0029. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of SNN-0029 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [26] | ||
ABI-011 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for ABI-011. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ABI-011 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [284] | ||
MP-0112 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for MP-0112. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of MP-0112 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [285] | ||
Navicixizumab [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Navicixizumab. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Navicixizumab through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [26] | ||
SFLT-01 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for SFLT-01. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of SFLT-01 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [241] | ||
ALN-VEG01 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for ALN-VEG01. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of ALN-VEG01 through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [286] | ||
Bevasiranib [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Vascular endothelial growth factor A (VEGFA) is a therapeutic target for Bevasiranib. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of Bevasiranib through regulating the expression of Vascular endothelial growth factor A (VEGFA). | [1], [275] | ||
References