Drug structure similarity searching is based on the Tanimoto similarity searching method. Molecular descriptors, including their quantitative representations of the structural and physicochemical features, have been extensively used in deriving structure-activity relationships, quantitative structure-activity relationships and virtual screening tools for drug discovery. Drugs with similar structures may have a similar response to m6A-centered regulation. Thus, according to the similar structure, you can input the structure of your interested drug, and retrieve its similar drugs with their corresponding target gene (s) regulated by m6A regulator in our database.