m6A-centered Drug Response Information
General Information of the Drug (ID: M6APDG02543)
| Name |
D-glucose
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| Synonyms |
(3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol; 2280-44-6; CPC hydrate; Cartose Cerelose; Clearsweet 95; Clintose L; D-Glc; D-Glcp; D-Glucopyranose; D-Glucopyranose, anhydrous; D-Glucopyranoside; D-glucose-ring; DSSTox_CID_2910; EINECS 218-914-5; Glc; Glc-OH; Glucodin; Glucopyranose; Glucopyranose, D-; Glucopyranoside; Glucose 40; Glucose solution; Meritose; Meritose 200; Roferose ST; Staleydex 130; Staleydex 95M; glc-ring
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| Status |
Approved
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| Structure |
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| Formula |
C6H12O6
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| InChI |
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1
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| InChIKey |
WQZGKKKJIJFFOK-GASJEMHNSA-N
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| PubChem CID | |||||
| VARIDT Drug ID | |||||
Target Gene(s) and Their Upstream m6A Regulator, Together with the Effect of Target Gene(s) in Drug Response
The target genes involved in drug-target interaction (such as drug-metabolizing enzymes, drug transporters and therapeutic targets) and drug-mediated cell death signaling (including modulating DNA damage and repair capacity, escaping from drug-induced apoptosis, autophagy, cellular metabolic reprogramming, oncogenic bypass signaling, cell microenvironment, cell stemness, etc.) could be regulated by m6A regulator(s) and affected their corresponding drug response. You can browse detailed information on drug-related target gene(s) mediated by m6A regulators.
Glucose transporter type 1 (SLC2A1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
| In total 1 mechanisms lead to this potential drug response | ||||
| Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for D-glucose. The Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) has potential in affecting the response of D-glucose through regulating the expression of Glucose transporter type 1 (SLC2A1). | [1], [2] | ||
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
| In total 1 mechanisms lead to this potential drug response | ||||
| Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for D-glucose. The Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has potential in affecting the response of D-glucose through regulating the expression of Glucose transporter type 1 (SLC2A1). | [1], [2] | ||
Methyltransferase-like 3 (METTL3)
| In total 1 mechanisms lead to this potential drug response | ||||
| Response Summary | Glucose transporter type 1 (SLC2A1) is a therapeutic target for D-glucose. The Methyltransferase-like 3 (METTL3) has potential in affecting the response of D-glucose through regulating the expression of Glucose transporter type 1 (SLC2A1). | [1], [2] | ||