m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00388)

Target Name	Stearoyl-CoA desaturase (SCD)
Synonyms	hSCD1; Acyl-CoA desaturase; Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase; FADS5; SCD1; SCDOS Click to Show/Hide
Gene Name	SCD
Chromosomal Location	10q24.31
Family	fatty acid desaturase type 1 family
Function	Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). Click to Show/Hide
Gene ID	6319
Uniprot ID	SCD_HUMAN
HGNC ID	HGNC:10571
KEGG ID	hsa:6319

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

SCD can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	MDA-MB-231	Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells Control: MDA-MB-231 cells		GSE70061
Regulation		logFC: -1.10E+00 p-value: 2.11E-02
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between SCD and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 1.17E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	Targeting METTL3/14 in vitro increases protein level of ACLY and Stearoyl-CoA desaturase (SCD) as well as triglyceride and cholesterol production and accumulation of lipid droplets. These findings demonstrate a new NAFLD mouse model that provides a study platform for DM2-related NAFLD and reveals a unique epitranscriptional regulating mechanism for lipid metabolism via m6A-modified protein expression of ACLY and SCD1.
Target Regulation	Up regulation
Responsed Disease	Non-alcoholic fatty liver disease		ICD-11: DB92	Disease Info
Pathway Response	Glycerolipid metabolism			hsa00561
Cell Process	Lipid metabolism
In-vitro Model	LM3	Malignant neoplasms	Mus musculus	CVCL_D269
In-vitro Model	MHCC97-H	Adult hepatocellular carcinoma	Homo sapiens	CVCL_4972
In-vivo Model	Mice with a Tmem30a deletion specifically in pancreatic beta cells were generated as previously described. Mice developed with NAFLD were named for Tmem30a-associated NAFLD (TAN) mice. The littermate mice with genotypes of Tmem30a^loxP/loxP were used as controls.

Methyltransferase-like 14 (METTL14) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL14*
Cell Line	HepG2 cell line	Homo sapiens
Treatment: shMETTL14 HepG2 cells Control: shCtrl HepG2 cells		GSE121949
Regulation		logFC: 1.25E+00 p-value: 7.56E-25
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	Targeting METTL3/14 in vitro increases protein level of ACLY and Stearoyl-CoA desaturase (SCD) as well as triglyceride and cholesterol production and accumulation of lipid droplets. These findings demonstrate a new NAFLD mouse model that provides a study platform for DM2-related NAFLD and reveals a unique epitranscriptional regulating mechanism for lipid metabolism via m6A-modified protein expression of ACLY and SCD1.
Target Regulation	Up regulation
Responsed Disease	Non-alcoholic fatty liver disease		ICD-11: DB92	Disease Info
Pathway Response	Glycerolipid metabolism			hsa00561
Cell Process	Lipid metabolism
In-vitro Model	LM3	Malignant neoplasms	Mus musculus	CVCL_D269
In-vitro Model	MHCC97-H	Adult hepatocellular carcinoma	Homo sapiens	CVCL_4972
In-vivo Model	Mice with a Tmem30a deletion specifically in pancreatic beta cells were generated as previously described. Mice developed with NAFLD were named for Tmem30a-associated NAFLD (TAN) mice. The littermate mice with genotypes of Tmem30a^loxP/loxP were used as controls.

YTH domain-containing protein 2 (YTHDC2) [READER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene			[6]
Response Summary	In nonalcoholic fatty liver disease, Ythdc2 could bind to mRNA of lipogenic genes, including sterol regulatory element-binding protein 1c, fatty acid synthase, Stearoyl-CoA desaturase (SCD), and acetyl-CoA carboxylase 1, to decrease their mRNA stability and inhibit gene expression.
Target Regulation	Down regulation
Responsed Disease	Non-alcoholic fatty liver disease	ICD-11: DB92	Disease Info
Pathway Response	RNA degradation		hsa03018
Cell Process	RNA stability
In-vivo Model	All mice were housed at 21℃ ± 1℃ with a humidity of 55% ± 10% and a 12-hour light/dark cycle. The high-fat diets (HFDs), containing 60% kcal from fat, 20% kcal from carbohydrate, and 20% kcal from protein.

Non-alcoholic fatty liver disease [ICD-11: DB92]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	Targeting METTL3/14 in vitro increases protein level of ACLY and Stearoyl-CoA desaturase (SCD) as well as triglyceride and cholesterol production and accumulation of lipid droplets. These findings demonstrate a new NAFLD mouse model that provides a study platform for DM2-related NAFLD and reveals a unique epitranscriptional regulating mechanism for lipid metabolism via m6A-modified protein expression of ACLY and SCD1.
Responsed Disease	Non-alcoholic fatty liver disease [ICD-11: DB92]
Target Regulator	Methyltransferase-like 14 (METTL14)		WRITER	Regulator Info
Target Regulation	Up regulation
Pathway Response	Glycerolipid metabolism			hsa00561
Cell Process	Lipid metabolism
In-vitro Model	LM3	Malignant neoplasms	Mus musculus	CVCL_D269
	MHCC97-H	Adult hepatocellular carcinoma	Homo sapiens	CVCL_4972
In-vivo Model	Mice with a Tmem30a deletion specifically in pancreatic beta cells were generated as previously described. Mice developed with NAFLD were named for Tmem30a-associated NAFLD (TAN) mice. The littermate mice with genotypes of Tmem30a^loxP/loxP were used as controls.
Experiment 2 Reporting the m6A-centered Disease Response				[6]
Response Summary	In nonalcoholic fatty liver disease, Ythdc2 could bind to mRNA of lipogenic genes, including sterol regulatory element-binding protein 1c, fatty acid synthase, Stearoyl-CoA desaturase (SCD), and acetyl-CoA carboxylase 1, to decrease their mRNA stability and inhibit gene expression.
Responsed Disease	Non-alcoholic fatty liver disease [ICD-11: DB92]
Target Regulator	YTH domain-containing protein 2 (YTHDC2)		READER	Regulator Info
Target Regulation	Down regulation
Pathway Response	RNA degradation			hsa03018
Cell Process	RNA stability
In-vivo Model	All mice were housed at 21℃ ± 1℃ with a humidity of 55% ± 10% and a 12-hour light/dark cycle. The high-fat diets (HFDs), containing 60% kcal from fat, 20% kcal from carbohydrate, and 20% kcal from protein.

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

DNA modification

m6A Regulator: Methyltransferase-like 16 (METTL16)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT02050		Crosstalk Info
Epigenetic Regulator	DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target	Methyltransferase 16, RNA N6-adenosine (METTL16)
Crosstalk relationship	DNA modification → m6A
Disease	Papillary Thyroid Cancer	Disease Info
Drug	Simvastatin	Drug Info

m6A Regulator: YTH domain-containing protein 2 (YTHDC2)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT02051		Crosstalk Info
Epigenetic Regulator	DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target	Methyltransferase 16, RNA N6-adenosine (METTL16)
Crosstalk relationship	DNA modification → m6A
Disease	Papillary Thyroid Cancer	Disease Info
Drug	Simvastatin	Drug Info

Histone modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03134		Crosstalk Info
Epigenetic Regulator	Lactate dehydrogenase A (LDHA)
Regulated Target	Histone H3 lysine 18 lactylation (H3K18lac)
Crosstalk relationship	Histone modification → m6A
Disease	Nonalcoholic fatty liver disease	Disease Info

m6A Regulator: YTH domain-containing family protein 1 (YTHDF1)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03135		Crosstalk Info
Epigenetic Regulator	Lactate dehydrogenase A (LDHA)
Regulated Target	Histone H3 lysine 18 lactylation (H3K18lac)
Crosstalk relationship	Histone modification → m6A
Disease	Nonalcoholic fatty liver disease	Disease Info

Non-coding RNA

m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05019		Crosstalk Info
Epigenetic Regulator	DARS1 antisense RNA 1 (DARS1-AS1)
Regulated Target	Insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3)
Crosstalk relationship	ncRNA → m6A
Disease	Cervical cancer	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00388)

Stearoyl-CoA desaturase (SCD)

N4-acetylcytidine (ac4C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000144		Click to Show/Hide the Full List
mod site	chr10:100364602-100364603:+		[7]
Sequence	ATTGGAGAAGCGGTGGATAACTAGCCAGACAAAATTTGAGA
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: ac4C_site_233

Adenosine-to-Inosine editing (A-to-I)

In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE004358		Click to Show/Hide the Full List
mod site	chr10:100353971-100353972:+		[8]
Sequence	GTTGTATGAGCTCTTTTGCAAGGCACCAGAATGGTGCACCC
Transcript ID List	ENST00000370355.3
External Link	RMBase: RNA-editing_site_18074
mod ID: A2ISITE004359		Click to Show/Hide the Full List
mod site	chr10:100361843-100361844:+		[8]
Sequence	TGGTAAAAACAGCAGCTCATAGAATTTTGAGTATTCCATGA
Transcript ID List	ENST00000370355.3
External Link	RMBase: RNA-editing_site_18075

5-methylcytidine (m5C)

In total 6 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004741		Click to Show/Hide the Full List
mod site	chr10:100348105-100348106:+		[9]
Sequence	CCACCACCATTACAGCGCCTCCCTCCAGGGTCCTGCAGAAT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m5C_site_5744
mod ID: M5CSITE004742		Click to Show/Hide the Full List
mod site	chr10:100348107-100348108:+		[9]
Sequence	ACCACCATTACAGCGCCTCCCTCCAGGGTCCTGCAGAATGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m5C_site_5745
mod ID: M5CSITE004743		Click to Show/Hide the Full List
mod site	chr10:100354483-100354484:+
Sequence	ACCACAAGTTTTCAGAAACACATGCTGATCCTCATAATTCC
Cell/Tissue List	lung
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m5C_site_5746
mod ID: M5CSITE004744		Click to Show/Hide the Full List
mod site	chr10:100362130-100362131:+		[9]
Sequence	AGTTGGGATGCCAATTTCCTCTCCACTGCTGGACATGAGAT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m5C_site_5747
mod ID: M5CSITE004745		Click to Show/Hide the Full List
mod site	chr10:100363382-100363383:+		[9]
Sequence	TGGAAGGGAGGAAGGCCTTTCTTCTGTGTTAATTGCGTAGA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m5C_site_5748
mod ID: M5CSITE004746		Click to Show/Hide the Full List
mod site	chr10:100364290-100364291:+
Sequence	GGTGGTTAAGGCCAGGGCCTCTCCAACCACTGTGCCACTGA
Cell/Tissue List	liver
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m5C_site_5749

N6-methyladenosine (m6A)

In total 115 m6A sequence/site(s) in this target gene
mod ID: M6ASITE001493		Click to Show/Hide the Full List
mod site	chr10:100347295-100347296:+		[10]
Sequence	GGGGGCTGAGGAAATACCGGACACGGTCACCCGTTGCCAGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; hESC-HEK293T; LCLs; MM6; TREX; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114339
mod ID: M6ASITE001494		Click to Show/Hide the Full List
mod site	chr10:100347343-100347344:+		[10]
Sequence	TTTAAATTCCCGGCTCGGGGACCTCCACGCACCGCGGCTAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; LCLs; MM6; TREX; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114340
mod ID: M6ASITE001495		Click to Show/Hide the Full List
mod site	chr10:100347369-100347370:+		[11]
Sequence	ACGCACCGCGGCTAGCGCCGACAACCAGCTAGCGTGCAAGG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114341
mod ID: M6ASITE001496		Click to Show/Hide the Full List
mod site	chr10:100347424-100347425:+		[10]
Sequence	GCGTACCGGCGGGCTTCGAAACCGCAGTCCTCCGGCGACCC
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; A549; HepG2; MT4; MM6; TREX; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114342
mod ID: M6ASITE001497		Click to Show/Hide the Full List
mod site	chr10:100347448-100347449:+		[10]
Sequence	CAGTCCTCCGGCGACCCCGAACTCCGCTCCGGAGCCTCAGC
Motif Score	3.373380952
Cell/Tissue List	HeLa; CD34; A549; HepG2; MT4; MM6; Huh7; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114343
mod ID: M6ASITE001498		Click to Show/Hide the Full List
mod site	chr10:100348096-100348097:+		[12]
Sequence	ATACCACCACCACCACCATTACAGCGCCTCCCTCCAGGGTC
Motif Score	2.07285119
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114344
mod ID: M6ASITE001499		Click to Show/Hide the Full List
mod site	chr10:100348169-100348170:+		[11]
Sequence	GCCCCTCTACTTGGAAGACGACATTCGCCCTGATATAAAAG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114345
mod ID: M6ASITE001500		Click to Show/Hide the Full List
mod site	chr10:100348202-100348203:+		[13]
Sequence	TATAAAAGATGATATATATGACCCCACCTACAAGGATAAGG
Motif Score	2.839113095
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114346
mod ID: M6ASITE001501		Click to Show/Hide the Full List
mod site	chr10:100348211-100348212:+		[11]
Sequence	TGATATATATGACCCCACCTACAAGGATAAGGAAGGCCCAA
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114347
mod ID: M6ASITE001502		Click to Show/Hide the Full List
mod site	chr10:100348259-100348260:+		[10]
Sequence	GGTTGAATATGTCTGGAGAAACATCATCCTTATGTCTCTGC
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T; MT4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114348
mod ID: M6ASITE001503		Click to Show/Hide the Full List
mod site	chr10:100348281-100348282:+		[11]
Sequence	ATCATCCTTATGTCTCTGCTACACTTGGGAGCCCTGTATGG
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114349
mod ID: M6ASITE001504		Click to Show/Hide the Full List
mod site	chr10:100348331-100348332:+		[14]
Sequence	GATTCCTACCTGCAAGTTCTACACCTGGCTTTGGGGTAAGC
Motif Score	2.078666667
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114350
mod ID: M6ASITE001505		Click to Show/Hide the Full List
mod site	chr10:100352437-100352438:+		[11]
Sequence	TCTGTGGAGCCACCGCTCTTACAAAGCTCGGCTGCCCCTAC
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114351
mod ID: M6ASITE001506		Click to Show/Hide the Full List
mod site	chr10:100352479-100352480:+		[11]
Sequence	GCTCTTTCTGATCATTGCCAACACAATGGCATTCCAGGTAA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114352
mod ID: M6ASITE001507		Click to Show/Hide the Full List
mod site	chr10:100354451-100354452:+		[13]
Sequence	TGTCTATGAATGGGCTCGTGACCACCGTGCCCACCACAAGT
Motif Score	2.839113095
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114353
mod ID: M6ASITE001508		Click to Show/Hide the Full List
mod site	chr10:100354466-100354467:+		[11]
Sequence	TCGTGACCACCGTGCCCACCACAAGTTTTCAGAAACACATG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114354
mod ID: M6ASITE001509		Click to Show/Hide the Full List
mod site	chr10:100354480-100354481:+		[10]
Sequence	CCCACCACAAGTTTTCAGAAACACATGCTGATCCTCATAAT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114355
mod ID: M6ASITE001510		Click to Show/Hide the Full List
mod site	chr10:100354506-100354507:+		[14]
Sequence	GCTGATCCTCATAATTCCCGACGTGGCTTTTTCTTCTCTCA
Motif Score	2.839505952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114356
mod ID: M6ASITE001511		Click to Show/Hide the Full List
mod site	chr10:100354551-100354552:+		[10]
Sequence	GGTTGGCTGCTTGTGCGCAAACACCCAGCTGTCAAAGAGAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293; hESC-HEK293T; HepG2
Seq Type List	m6A-seq; m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114357
mod ID: M6ASITE001512		Click to Show/Hide the Full List
mod site	chr10:100354586-100354587:+		[10]
Sequence	AGAGAAGGGGAGTACGCTAGACTTGTCTGACCTAGAAGCTG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114358
mod ID: M6ASITE001513		Click to Show/Hide the Full List
mod site	chr10:100354611-100354612:+		[10]
Sequence	TCTGACCTAGAAGCTGAGAAACTGGTGATGTTCCAGAGGAG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114359
mod ID: M6ASITE001514		Click to Show/Hide the Full List
mod site	chr10:100356536-100356537:+		[11]
Sequence	GGTCTGTCAATGTAGGTACTACAAACCTGGCTTGCTGATGA
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114360
mod ID: M6ASITE001515		Click to Show/Hide the Full List
mod site	chr10:100356540-100356541:+		[10]
Sequence	TGTCAATGTAGGTACTACAAACCTGGCTTGCTGATGATGTG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114361
mod ID: M6ASITE001516		Click to Show/Hide the Full List
mod site	chr10:100356604-100356605:+		[10]
Sequence	CCTGGTATTTCTGGGGTGAAACTTTTCAAAACAGTGTGTTC
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114362
mod ID: M6ASITE001517		Click to Show/Hide the Full List
mod site	chr10:100356614-100356615:+		[10]
Sequence	CTGGGGTGAAACTTTTCAAAACAGTGTGTTCGTTGCCACTT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114363
mod ID: M6ASITE001518		Click to Show/Hide the Full List
mod site	chr10:100356677-100356678:+		[10]
Sequence	TAATGCCACCTGGCTGGTGAACAGTGCTGCCCACCTCTTCG
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114364
mod ID: M6ASITE001519		Click to Show/Hide the Full List
mod site	chr10:100356719-100356720:+		[10]
Sequence	ATATCGTCCTTATGACAAGAACATTAGCCCCCGGGAGAATA
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114365
mod ID: M6ASITE001520		Click to Show/Hide the Full List
mod site	chr10:100356750-100356751:+		[14]
Sequence	CGGGAGAATATCCTGGTTTCACTTGGAGCTGTGGGTAAGTC
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114366
mod ID: M6ASITE001521		Click to Show/Hide the Full List
mod site	chr10:100360745-100360746:+		[14]
Sequence	TGTTTCAGGTGAGGGCTTCCACAACTACCACCACTCCTTTC
Motif Score	2.053113095
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114367
mod ID: M6ASITE001522		Click to Show/Hide the Full List
mod site	chr10:100360799-100360800:+		[11]
Sequence	TGCCAGTGAGTACCGCTGGCACATCAACTTCACCACATTCT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114368
mod ID: M6ASITE001523		Click to Show/Hide the Full List
mod site	chr10:100360813-100360814:+		[11]
Sequence	GCTGGCACATCAACTTCACCACATTCTTCATTGATTGCATG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114369
mod ID: M6ASITE001524		Click to Show/Hide the Full List
mod site	chr10:100360903-100360904:+		[10]
Sequence	TCTTGGCCAGGATTAAAAGAACCGGAGATGGAAACTACAAG
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114370
mod ID: M6ASITE001525		Click to Show/Hide the Full List
mod site	chr10:100360916-100360917:+		[10]
Sequence	TAAAAGAACCGGAGATGGAAACTACAAGAGTGGCTGAGTTT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114371
mod ID: M6ASITE001526		Click to Show/Hide the Full List
mod site	chr10:100360919-100360920:+		[11]
Sequence	AAGAACCGGAGATGGAAACTACAAGAGTGGCTGAGTTTGGG
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114372
mod ID: M6ASITE001527		Click to Show/Hide the Full List
mod site	chr10:100360964-100360965:+		[10]
Sequence	CTCAGGTTCCTTTTTCAAAAACCAGCCAGGCAGAGGTTTTA
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114373
mod ID: M6ASITE001528		Click to Show/Hide the Full List
mod site	chr10:100361091-100361092:+		[14]
Sequence	TTCAAAAGTATTGAAAGCCAACAACTCTGCCTTTATGATGC
Motif Score	2.173910714
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114374
mod ID: M6ASITE001529		Click to Show/Hide the Full List
mod site	chr10:100361262-100361263:+		[10]
Sequence	GTCCAGCTTCCAAAGCCTAGACAACCTTTCTGTAGCCTAAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114375
mod ID: M6ASITE001530		Click to Show/Hide the Full List
mod site	chr10:100361283-100361284:+		[14]
Sequence	CAACCTTTCTGTAGCCTAAAACGAATGGTCTTTGCTCCAGA
Motif Score	2.179660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114376
mod ID: M6ASITE001531		Click to Show/Hide the Full List
mod site	chr10:100361445-100361446:+		[14]
Sequence	TGGAAAAGCAACTTCATTTGACACAAAGCTTCTAAAGCAGG
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114377
mod ID: M6ASITE001532		Click to Show/Hide the Full List
mod site	chr10:100361530-100361531:+		[10]
Sequence	AGGGAAGCGAAGCAAGAGGAACCTCTCGCCATGATCAGACA
Motif Score	2.930744048
Cell/Tissue List	HeLa; AML
Seq Type List	m6A-seq; miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114378
mod ID: M6ASITE001533		Click to Show/Hide the Full List
mod site	chr10:100361548-100361549:+		[10]
Sequence	GAACCTCTCGCCATGATCAGACATACAGCTGCCTACCTAAT
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114379
mod ID: M6ASITE001534		Click to Show/Hide the Full List
mod site	chr10:100361573-100361574:+		[10]
Sequence	CAGCTGCCTACCTAATGAGGACTTCAAGCCCCACCACATAG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114380
mod ID: M6ASITE001535		Click to Show/Hide the Full List
mod site	chr10:100361588-100361589:+		[11]
Sequence	TGAGGACTTCAAGCCCCACCACATAGCATGCTTCCTTTCTC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114381
mod ID: M6ASITE001536		Click to Show/Hide the Full List
mod site	chr10:100361666-100361667:+		[11]
Sequence	AATGCTAATTCAATGCCGCAACATATAGTTGAGGCCGAGGA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114382
mod ID: M6ASITE001537		Click to Show/Hide the Full List
mod site	chr10:100361697-100361698:+		[10]
Sequence	AGGCCGAGGATAAAGAAAAGACATTTTAAGTTTGTAGTAAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114383
mod ID: M6ASITE001538		Click to Show/Hide the Full List
mod site	chr10:100361765-100361766:+		[14]
Sequence	TTTTCTTTTTTTCTTTAATAACAAGGAGATTTCTTAGTTCA
Motif Score	2.168095238
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114384
mod ID: M6ASITE001539		Click to Show/Hide the Full List
mod site	chr10:100361831-100361832:+		[10]
Sequence	TGTTTCCAGAATTGGTAAAAACAGCAGCTCATAGAATTTTG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114385
mod ID: M6ASITE001540		Click to Show/Hide the Full List
mod site	chr10:100361958-100361959:+		[10]
Sequence	GATGGCTGTGGCATTTCCAAACATCCAAAAAAAGGGAAGGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114386
mod ID: M6ASITE001541		Click to Show/Hide the Full List
mod site	chr10:100362018-100362019:+		[14]
Sequence	GTCAAAAATAAAATATATATACATATATACATTGCTTAGAA
Motif Score	2.110482143
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114387
mod ID: M6ASITE001542		Click to Show/Hide the Full List
mod site	chr10:100362026-100362027:+		[11]
Sequence	TAAAATATATATACATATATACATTGCTTAGAACGTTAAAC
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114388
mod ID: M6ASITE001543		Click to Show/Hide the Full List
mod site	chr10:100362038-100362039:+		[14]
Sequence	ACATATATACATTGCTTAGAACGTTAAACTATTAGAGTATT
Motif Score	2.925321429
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114389
mod ID: M6ASITE001544		Click to Show/Hide the Full List
mod site	chr10:100362045-100362046:+		[10]
Sequence	TACATTGCTTAGAACGTTAAACTATTAGAGTATTTCCCTTC
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114390
mod ID: M6ASITE001545		Click to Show/Hide the Full List
mod site	chr10:100362088-100362089:+		[10]
Sequence	AAGAGGGATGTTTGGAAAAAACTCTGAAGGAGAGGAGGAAT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114391
mod ID: M6ASITE001546		Click to Show/Hide the Full List
mod site	chr10:100362142-100362143:+		[10]
Sequence	AATTTCCTCTCCACTGCTGGACATGAGATGGAGAGGCTGAG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114392
mod ID: M6ASITE001547		Click to Show/Hide the Full List
mod site	chr10:100362165-100362166:+		[10]
Sequence	TGAGATGGAGAGGCTGAGGGACAGGATCTATAGGCAGCTTC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; HepG2
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114393
mod ID: M6ASITE001548		Click to Show/Hide the Full List
mod site	chr10:100362195-100362196:+		[15]
Sequence	TAGGCAGCTTCTAAGAGCGAACTTCACATAGGAAGGGATCT
Motif Score	3.373380952
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114394
mod ID: M6ASITE001549		Click to Show/Hide the Full List
mod site	chr10:100362220-100362221:+		[11]
Sequence	ACATAGGAAGGGATCTGAGAACACGTTGCCAGGGGCTTGAG
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T; HepG2
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114395
mod ID: M6ASITE001550		Click to Show/Hide the Full List
mod site	chr10:100362247-100362248:+		[14]
Sequence	GCCAGGGGCTTGAGAAGGTTACTGAGTGAGTTATTGGGAGT
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114396
mod ID: M6ASITE001551		Click to Show/Hide the Full List
mod site	chr10:100362338-100362339:+		[14]
Sequence	TCTCCTTGAAATGAGTAAAAACTAGAAGGCTTCTCTCCACA
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114397
mod ID: M6ASITE001552		Click to Show/Hide the Full List
mod site	chr10:100362410-100362411:+		[14]
Sequence	GGAGAAGGGGGTCTCTGTTAACATCTAGCCTAAAGTATACA
Motif Score	2.168095238
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114398
mod ID: M6ASITE001553		Click to Show/Hide the Full List
mod site	chr10:100362428-100362429:+		[11]
Sequence	TAACATCTAGCCTAAAGTATACAACTGCCTGGGGGGCAGGG
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114399
mod ID: M6ASITE001554		Click to Show/Hide the Full List
mod site	chr10:100362463-100362464:+		[14]
Sequence	GCAGGGTTAGGAATCTCTTCACTACCCTGATTCTTGATTCC
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114400
mod ID: M6ASITE001555		Click to Show/Hide the Full List
mod site	chr10:100362466-100362467:+		[14]
Sequence	GGGTTAGGAATCTCTTCACTACCCTGATTCTTGATTCCTGG
Motif Score	2.05802381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114401
mod ID: M6ASITE001556		Click to Show/Hide the Full List
mod site	chr10:100362514-100362515:+		[14]
Sequence	CTGTCTGTCCCTTTTCTTTGACCAGATCTTTCTCTTCCCTG
Motif Score	2.839113095
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114402
mod ID: M6ASITE001557		Click to Show/Hide the Full List
mod site	chr10:100362556-100362557:+		[11]
Sequence	ACGTTTTCTTCTTTCCCTGGACAGGCAGCCTCCTTTGTGTG
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T; AML
Seq Type List	MAZTER-seq; miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114403
mod ID: M6ASITE001558		Click to Show/Hide the Full List
mod site	chr10:100362595-100362596:+		[14]
Sequence	TGTATTCAGAGGCAGTGATGACTTGCTGTCCAGGCAGCTCC
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114404
mod ID: M6ASITE001559		Click to Show/Hide the Full List
mod site	chr10:100362623-100362624:+		[11]
Sequence	TCCAGGCAGCTCCCTCCTGCACACAGAATGCTCAGGGTCAC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114405
mod ID: M6ASITE001560		Click to Show/Hide the Full List
mod site	chr10:100362642-100362643:+		[14]
Sequence	CACACAGAATGCTCAGGGTCACTGAACCACTGCTTCTCTTT
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114406
mod ID: M6ASITE001561		Click to Show/Hide the Full List
mod site	chr10:100362647-100362648:+		[15]
Sequence	AGAATGCTCAGGGTCACTGAACCACTGCTTCTCTTTTGAAA
Motif Score	2.930744048
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114407
mod ID: M6ASITE001562		Click to Show/Hide the Full List
mod site	chr10:100362715-100362716:+		[11]
Sequence	CCTCCGCAGTGTCTCCACCTACACCCCTGTGCTCCCCTGCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114408
mod ID: M6ASITE001563		Click to Show/Hide the Full List
mod site	chr10:100362752-100362753:+		[15]
Sequence	TGCCACACTGATGGCTCAAGACAAGGCTGGCAAACCCTCCC
Motif Score	2.897386905
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114409
mod ID: M6ASITE001564		Click to Show/Hide the Full List
mod site	chr10:100362765-100362766:+		[15]
Sequence	GCTCAAGACAAGGCTGGCAAACCCTCCCAGAAACATCTCTG
Motif Score	2.185083333
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114410
mod ID: M6ASITE001565		Click to Show/Hide the Full List
mod site	chr10:100362777-100362778:+		[11]
Sequence	GCTGGCAAACCCTCCCAGAAACATCTCTGGCCCAGAAAGCC
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T; HepG2
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114411
mod ID: M6ASITE001566		Click to Show/Hide the Full List
mod site	chr10:100362825-100362826:+		[12]
Sequence	CCCTCCCTCTCTCATGAGGCACAGCCAAGCCAAGCGCTCAT
Motif Score	2.830589286
Cell/Tissue List	liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114412
mod ID: M6ASITE001567		Click to Show/Hide the Full List
mod site	chr10:100362866-100362867:+		[11]
Sequence	GTTGAGCCAGTGGGCCAGCCACAGAGCAAAAGAGGGTTTAT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114413
mod ID: M6ASITE001568		Click to Show/Hide the Full List
mod site	chr10:100362913-100362914:+		[15]
Sequence	TCCCCTCTCTCTGGGTCAGAACCAGAGGGCATGCTGAATGC
Motif Score	2.930744048
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114414
mod ID: M6ASITE001569		Click to Show/Hide the Full List
mod site	chr10:100363014-100363015:+		[16]
Sequence	GCTTGTAGAAGTAGGAGGAAACAGTTCTCACTGGGAAGAAG
Motif Score	2.20572619
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114415
mod ID: M6ASITE001570		Click to Show/Hide the Full List
mod site	chr10:100363046-100363047:+		[16]
Sequence	GGGAAGAAGCAAGGGCAAGAACCCAAGTGCCTCACCTCGAA
Motif Score	2.930744048
Cell/Tissue List	HepG2; H1299; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114416
mod ID: M6ASITE001571		Click to Show/Hide the Full List
mod site	chr10:100363097-100363098:+		[16]
Sequence	GTTCCCTGGAGTCAGGGTGAACTGCAAAGCTTTGGCTGAGA
Motif Score	3.373380952
Cell/Tissue List	HepG2; H1299; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114417
mod ID: M6ASITE001572		Click to Show/Hide the Full List
mod site	chr10:100363117-100363118:+		[16]
Sequence	ACTGCAAAGCTTTGGCTGAGACCTGGGATTTGAGATACCAC
Motif Score	2.876744048
Cell/Tissue List	HepG2; H1299; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114418
mod ID: M6ASITE001573		Click to Show/Hide the Full List
mod site	chr10:100363136-100363137:+		[11]
Sequence	GACCTGGGATTTGAGATACCACAAACCCTGCTGAACACAGT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114419
mod ID: M6ASITE001574		Click to Show/Hide the Full List
mod site	chr10:100363140-100363141:+		[17]
Sequence	TGGGATTTGAGATACCACAAACCCTGCTGAACACAGTGTCT
Motif Score	2.185083333
Cell/Tissue List	HepG2; BGC823; H1299; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114420
mod ID: M6ASITE001575		Click to Show/Hide the Full List
mod site	chr10:100363150-100363151:+		[17]
Sequence	GATACCACAAACCCTGCTGAACACAGTGTCTGTTCAGCAAA
Motif Score	2.951386905
Cell/Tissue List	HepG2; BGC823; H1299; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114421
mod ID: M6ASITE001576		Click to Show/Hide the Full List
mod site	chr10:100363170-100363171:+		[17]
Sequence	ACACAGTGTCTGTTCAGCAAACTAACCAGCATTCCCTACAG
Motif Score	2.627720238
Cell/Tissue List	HepG2; BGC823; H1299; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114422
mod ID: M6ASITE001577		Click to Show/Hide the Full List
mod site	chr10:100363201-100363202:+		[11]
Sequence	TTCCCTACAGCCTAGGGCAGACAATAGTATAGAAGTCTGGA
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T; BGC823; H1299; AML
Seq Type List	MAZTER-seq; m6A-seq; miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114423
mod ID: M6ASITE001578		Click to Show/Hide the Full List
mod site	chr10:100363227-100363228:+		[14]
Sequence	GTATAGAAGTCTGGAAAAAAACAAAAACAGAATTTGAGAAC
Motif Score	2.20572619
Cell/Tissue List	HEK293T; BGC823; H1299
Seq Type List	DART-seq; m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114424
mod ID: M6ASITE001579		Click to Show/Hide the Full List
mod site	chr10:100363233-100363234:+		[18]
Sequence	AAGTCTGGAAAAAAACAAAAACAGAATTTGAGAACCTTGGA
Motif Score	2.20572619
Cell/Tissue List	BGC823; H1299
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114425
mod ID: M6ASITE001580		Click to Show/Hide the Full List
mod site	chr10:100363246-100363247:+		[18]
Sequence	AACAAAAACAGAATTTGAGAACCTTGGACCACTCCTGTCCC
Motif Score	2.930744048
Cell/Tissue List	BGC823; H1299
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114426
mod ID: M6ASITE001581		Click to Show/Hide the Full List
mod site	chr10:100363253-100363254:+		[18]
Sequence	ACAGAATTTGAGAACCTTGGACCACTCCTGTCCCTGTAGCT
Motif Score	3.622404762
Cell/Tissue List	BGC823; H1299; AML
Seq Type List	m6A-seq; miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114427
mod ID: M6ASITE001582		Click to Show/Hide the Full List
mod site	chr10:100363323-100363324:+		[11]
Sequence	TCTATTAAGATTGGAAATGTACACTACCAAACACTCAGTCC
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114428
mod ID: M6ASITE001583		Click to Show/Hide the Full List
mod site	chr10:100363333-100363334:+		[11]
Sequence	TTGGAAATGTACACTACCAAACACTCAGTCCACTGTTGAGC
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T; BGC823
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114429
mod ID: M6ASITE001584		Click to Show/Hide the Full List
mod site	chr10:100363423-100363424:+		[14]
Sequence	GGCTACAGGGGTTAGCCTGGACTAAAGGCATCCTTGTCTTT
Motif Score	4.065041667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114430
mod ID: M6ASITE001585		Click to Show/Hide the Full List
mod site	chr10:100363485-100363486:+		[14]
Sequence	AAAGGATCTAAGGGAAGATCACTGTAGTTTAGTTCTGTTGA
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114431
mod ID: M6ASITE001586		Click to Show/Hide the Full List
mod site	chr10:100363586-100363587:+		[14]
Sequence	GCCTGCTTGATAATATATAAACAATAAAAACAACTTTCACT
Motif Score	2.20572619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114432
mod ID: M6ASITE001587		Click to Show/Hide the Full List
mod site	chr10:100363595-100363596:+		[11]
Sequence	ATAATATATAAACAATAAAAACAACTTTCACTTCTTCCTAT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114433
mod ID: M6ASITE001588		Click to Show/Hide the Full List
mod site	chr10:100363598-100363599:+		[14]
Sequence	ATATATAAACAATAAAAACAACTTTCACTTCTTCCTATTGT
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114434
mod ID: M6ASITE001589		Click to Show/Hide the Full List
mod site	chr10:100363656-100363657:+		[14]
Sequence	CTGATCTGTACCATGACCCTACATAAGGCTGGATGGCACCT
Motif Score	2.078666667
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114435
mod ID: M6ASITE001590		Click to Show/Hide the Full List
mod site	chr10:100363743-100363744:+		[10]
Sequence	GTGTGTCTGCTGAGTAAGGAACACGATTTTCAAGATTCTAA
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114436
mod ID: M6ASITE001591		Click to Show/Hide the Full List
mod site	chr10:100363794-100363795:+		[10]
Sequence	AAGTGACACATTAATGATAAACTCAGATCTGATCAAGAGTC
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114437
mod ID: M6ASITE001592		Click to Show/Hide the Full List
mod site	chr10:100363945-100363946:+		[10]
Sequence	AGAATCCCTTTGCACCTGAGACCCTACTGAAGTGGCTGGTA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114438
mod ID: M6ASITE001593		Click to Show/Hide the Full List
mod site	chr10:100363950-100363951:+		[14]
Sequence	CCCTTTGCACCTGAGACCCTACTGAAGTGGCTGGTAGAAAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114439
mod ID: M6ASITE001594		Click to Show/Hide the Full List
mod site	chr10:100364070-100364071:+		[11]
Sequence	GCTGCTTTTCTTAAGTGCCCACATTTGATGGAGGGTGGAAA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114440
mod ID: M6ASITE001595		Click to Show/Hide the Full List
mod site	chr10:100364388-100364389:+		[14]
Sequence	GTTAAAATGGGGATAATAATACTGACCTACCTCAAAGGGCA
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	rmsk_3397884; ENST00000370355.3
External Link	RMBase: m6A_site_114441
mod ID: M6ASITE001596		Click to Show/Hide the Full List
mod site	chr10:100364475-100364476:+		[10]
Sequence	TCAGCACAGGAATTCTCAAGACCTGAGTATTTTTTATAATA
Motif Score	2.876744048
Cell/Tissue List	HeLa; hESCs; fibroblasts; A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114442
mod ID: M6ASITE001597		Click to Show/Hide the Full List
mod site	chr10:100364512-100364513:+		[10]
Sequence	AATAGGAATGTCCACCATGAACTTGATACGTCCGTGTGTCC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; hNPCs; hESCs; fibroblasts; A549; AML
Seq Type List	m6A-seq; DART-seq; miCLIP
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114443
mod ID: M6ASITE001598		Click to Show/Hide the Full List
mod site	chr10:100364569-100364570:+		[10]
Sequence	TCTATATGGTTCTCCAAGAAACTGAATGAATCCATTGGAGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; hNPCs; hESCs; fibroblasts; A549
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114444
mod ID: M6ASITE001599		Click to Show/Hide the Full List
mod site	chr10:100364610-100364611:+		[10]
Sequence	AGCGGTGGATAACTAGCCAGACAAAATTTGAGAATACATAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; hNPCs; hESCs; fibroblasts; A549
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114445
mod ID: M6ASITE001600		Click to Show/Hide the Full List
mod site	chr10:100364631-100364632:+		[10]
Sequence	CAAAATTTGAGAATACATAAACAACGCATTGCCACGGAAAC
Motif Score	2.20572619
Cell/Tissue List	HeLa; hNPCs; hESCs; fibroblasts; A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114446
mod ID: M6ASITE001601		Click to Show/Hide the Full List
mod site	chr10:100364634-100364635:+		[14]
Sequence	AATTTGAGAATACATAAACAACGCATTGCCACGGAAACATA
Motif Score	2.147845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114447
mod ID: M6ASITE001602		Click to Show/Hide the Full List
mod site	chr10:100364650-100364651:+		[10]
Sequence	AACAACGCATTGCCACGGAAACATACAGAGGATGCCTTTTC
Motif Score	2.20572619
Cell/Tissue List	HeLa; hNPCs; fibroblasts; A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114448
mod ID: M6ASITE001603		Click to Show/Hide the Full List
mod site	chr10:100364654-100364655:+		[14]
Sequence	ACGCATTGCCACGGAAACATACAGAGGATGCCTTTTCTGTG
Motif Score	2.110482143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114449
mod ID: M6ASITE001604		Click to Show/Hide the Full List
mod site	chr10:100364718-100364719:+		[14]
Sequence	TTATGTGGGATATAGTAGTTACTTGTGACAAGAATAATTTT
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114450
mod ID: M6ASITE001605		Click to Show/Hide the Full List
mod site	chr10:100364725-100364726:+		[14]
Sequence	GGATATAGTAGTTACTTGTGACAAGAATAATTTTGGAATAA
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114451
mod ID: M6ASITE001606		Click to Show/Hide the Full List
mod site	chr10:100364761-100364762:+		[14]
Sequence	AATAATTTCTATTAATATCAACTCTGAAGCTAATTGTACTA
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114452
mod ID: M6ASITE001607		Click to Show/Hide the Full List
mod site	chr10:100364778-100364779:+		[14]
Sequence	TCAACTCTGAAGCTAATTGTACTAATCTGAGATTGTGTTTG
Motif Score	3.278136905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: m6A_site_114453

2'-O-Methylation (2'-O-Me)

In total 2 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000576		Click to Show/Hide the Full List
mod site	chr10:100362092-100362093:+		[19]
Sequence	GGGATGTTTGGAAAAAACTCTGAAGGAGAGGAGGAATTAGT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: Nm_site_810
mod ID: 2OMSITE000577		Click to Show/Hide the Full List
mod site	chr10:100363099-100363100:+		[19]
Sequence	TCCCTGGAGTCAGGGTGAACTGCAAAGCTTTGGCTGAGACC
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000370355.3
External Link	RMBase: Nm_site_811

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000306		Click to Show/Hide the Full List
mod site	chr10:100347418-100347419:+		[20]
Sequence	CTCAGCGCGTACCGGCGGGCTTCGAAACCGCAGTCCTCCGG
Transcript ID List	ENST00000370355.3
External Link	RMBase: Pseudo_site_749

Ref 1	Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma. Mol Ther. 2022 Jun 1;30(6):2342-2353. doi: 10.1016/j.ymthe.2022.02.021. Epub 2022 Feb 19.
Ref 2	Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats. Eur J Pharmacol. 2004 Oct 6;501(1-3):151-9.
Ref 3	Tamibarotene. Drugs Today (Barc). 2007 Aug;43(8):563-8. doi: 10.1358/dot.2007.43.8.1072615.
Ref 4	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
Ref 5	J Clin Oncol 32:5s, 2014 (suppl; abstr 2515).
Ref 6	N(6) -Methyladenosine Reader Protein YT521-B Homology Domain-Containing 2 Suppresses Liver Steatosis by Regulation of mRNA Stability of Lipogenic Genes. Hepatology. 2021 Jan;73(1):91-103. doi: 10.1002/hep.31220. Epub 2020 Oct 25.
Ref 7	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 8	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 9	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 10	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 11	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 12	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 13	The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.
Ref 14	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 15	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 16	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 17	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 18	METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer. Mol Cancer. 2019 Oct 13;18(1):142. doi: 10.1186/s12943-019-1065-4.
Ref 19	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.
Ref 20	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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