General Information of the Disease (ID: M6ADIS0312)
Name
Papillary Thyroid Cancer
ICD
ICD-11: XH1ND9
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease
In total 3 item(s) under this disease
Crosstalk ID: M6ACROT02050
m6A Regulator Methyltransferase-like 16 (METTL16)
m6A Target Stearoyl-CoA desaturase (SCD)
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase 16, RNA N6-adenosine (METTL16)
Crosstalk relationship DNA modification → m6A
Drug Simvastatin
Crosstalk ID: M6ACROT02051
m6A Regulator YTH domain-containing protein 2 (YTHDC2)
m6A Target Stearoyl-CoA desaturase (SCD)
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase 16, RNA N6-adenosine (METTL16)
Crosstalk relationship DNA modification → m6A
Drug Simvastatin
Crosstalk ID: M6ACROT05207
m6A Regulator RNA demethylase ALKBH5 (ALKBH5)
m6A Target hsa-miR-506-3p
Epigenetic Regulator Circ_NRCAM
Regulated Target RNA demethylase ALKBH5 (ALKBH5)
Crosstalk relationship ncRNA → m6A
References
Ref 1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
Ref 2 Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy. J Clin Med. 2020 Oct 16;9(10):3323. doi: 10.3390/jcm9103323.