General Information of the Disease (ID: M6ADIS0343)
Name
Clear cell renal cell carcinoma
ICD
ICD-11: XH46F1
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease
In total 3 item(s) under this disease
Crosstalk ID: M6ACROT03121
m6A Regulator YTH domain-containing protein 1 (YTHDC1)
m6A Target Annexin A1 (ANXA1)
Epigenetic Regulator Histone deacetylase 2 (HDAC2)
Crosstalk relationship Histone modification → m6A
Drug Sunitinib
Crosstalk ID: M6ACROT05005
m6A Regulator Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
m6A Target C-terminal-binding protein 1 (CTBP1)
Epigenetic Regulator Long intergenic non-protein coding RNA 1426 (LINC01426)
Regulated Target Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1)
Crosstalk relationship ncRNA → m6A
Crosstalk ID: M6ACROT05346
m6A Regulator Fat mass and obesity-associated protein (FTO)
m6A Target PPAR-gamma coactivator 1-alpha (PGC-1a/PPARGC1A)
Epigenetic Regulator MicroRNA 155 (MIR155)
Regulated Target FTO alpha-ketoglutarate dependent dioxygenase (FTO)
Crosstalk relationship ncRNA → m6A
References
Ref 1 Development of a cancer vaccine: peptides, proteins, and DNA. Cancer Chemother Pharmacol. 2000;46 Suppl:S77-82. doi: 10.1007/s002800000179.
Ref 2 J Clin Oncol 32:5s, 2014 (suppl; abstr 2507).