m6A Regulator and Potential Drug Response
General Information of the m6A Regulator (ID: REG00001)
Regulator Name | Fat mass and obesity-associated protein (FTO) | ||||
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Synonyms |
Alpha-ketoglutarate-dependent dioxygenase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO; KIAA1752
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Gene Name | FTO | ||||
Regulator Type | WRITER ERASER READER | ||||
Regulator Link | Click to View Full Information of This Regulator |
Full List of Target Gene(s) of This m6A Regulator and Corresponding Potential Drug Response(s)
Alanine/serine/cysteine/threonine transporter 2 (SLC1A5)
Acyclovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for Acyclovir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Acyclovir through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [2] | ||
D-serine [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for D-serine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of D-serine through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [3] | ||
Ganciclovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for Ganciclovir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ganciclovir through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [2] | ||
Glycine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for Glycine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Glycine through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [4] | ||
L-carnitine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for L-carnitine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-carnitine through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [5] | ||
L-glutamine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for L-glutamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-glutamine through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [6] | ||
Valacyclovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for Valacyclovir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Valacyclovir through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [7] | ||
Valganciclovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for Valganciclovir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Valganciclovir through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [8] | ||
Nitric oxide [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for Nitric oxide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nitric oxide through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [9] | ||
L-threonine [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for L-threonine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-threonine through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [3] | ||
benzylserine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for benzylserine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of benzylserine through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [10] | ||
p-nitrophenyl glutamyl anilide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) is a therapeutic target for p-nitrophenyl glutamyl anilide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of p-nitrophenyl glutamyl anilide through regulating the expression of Alanine/serine/cysteine/threonine transporter 2 (SLC1A5). | [1], [11] | ||
Apolipoprotein E (APOE)
AEM-28 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apolipoprotein E (APOE) is a therapeutic target for AEM-28. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AEM-28 through regulating the expression of Apolipoprotein E (APOE). | [12], [13] | ||
CN-105 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apolipoprotein E (APOE) is a therapeutic target for CN-105. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CN-105 through regulating the expression of Apolipoprotein E (APOE). | [12], [14] | ||
Apolipoprotein E [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apolipoprotein E (APOE) is a therapeutic target for Apolipoprotein E. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Apolipoprotein E through regulating the expression of Apolipoprotein E (APOE). | [12], [15] | ||
Apoptosis mediating surface antigen FAS (FAS)
VB-111 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for VB-111. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VB-111 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [17] | ||
APG-101 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for APG-101. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APG-101 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [18] | ||
DE-098 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for DE-098. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DE-098 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [19] | ||
APO-010 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for APO-010. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APO-010 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [20] | ||
2-aminophenoxazine-3-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for 2-aminophenoxazine-3-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-aminophenoxazine-3-one through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [21] | ||
APG-103 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for APG-103. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APG-103 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [22] | ||
F61F12 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for F61F12. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of F61F12 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [23] | ||
ISIS 17020 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis mediating surface antigen FAS (FAS) is a therapeutic target for ISIS 17020. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 17020 through regulating the expression of Apoptosis mediating surface antigen FAS (FAS). | [16], [24] | ||
Apoptosis regulator Bcl-2 (BCL-2)
MCI-186 [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for MCI-186. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MCI-186 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [26] | ||
Venetoclax [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Venetoclax. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Venetoclax through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [27] | ||
ABT-263 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for ABT-263. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABT-263 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [28] | ||
Oblimersen [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Oblimersen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Oblimersen through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [29] | ||
RG7601 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for RG7601. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RG7601 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [30] | ||
Thymoquinone [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Thymoquinone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Thymoquinone through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [31] | ||
APG-1252 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for APG-1252. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APG-1252 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [32] | ||
APG-2575 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for APG-2575. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APG-2575 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [33] | ||
AZD0466 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for AZD0466. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD0466 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [34] | ||
Beclanorsen [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Beclanorsen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Beclanorsen through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [35] | ||
Gossypol [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Gossypol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gossypol through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [36] | ||
Obatoclax [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Obatoclax. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Obatoclax through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [22], [25] | ||
PNT-2258 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for PNT-2258. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PNT-2258 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [37] | ||
AI-850 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for AI-850. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AI-850 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [38] | ||
BCL201 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for BCL201. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BCL201 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [39] | ||
BGB-11417 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for BGB-11417. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BGB-11417 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [40] | ||
BP1002 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for BP1002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BP1002 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [41] | ||
LP-108 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for LP-108. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LP-108 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [42] | ||
Pc4 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Pc4. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pc4 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [43] | ||
VOB560 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for VOB560. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VOB560 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [44] | ||
2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for 2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [45] | ||
4,5-dibenzylbenzene-1,2-diol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for 4,5-dibenzylbenzene-1,2-diol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4,5-dibenzylbenzene-1,2-diol through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [46] | ||
5,10-Dioxy-2-phenyl-benzo[g]pteridin-4-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for 5,10-Dioxy-2-phenyl-benzo[g]pteridin-4-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,10-Dioxy-2-phenyl-benzo[g]pteridin-4-ylamine through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [47] | ||
Apogossypol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for Apogossypol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Apogossypol through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [48] | ||
BP-100-1.02 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for BP-100-1.02. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BP-100-1.02 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [49] | ||
modified HA14-1 compounds (cancer) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for modified HA14-1 compounds (cancer). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of modified HA14-1 compounds (cancer) through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [47] | ||
N-phenyl-2,3,4-trihydroxy-5-benzyl-benzamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for N-phenyl-2,3,4-trihydroxy-5-benzyl-benzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-phenyl-2,3,4-trihydroxy-5-benzyl-benzamide through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [47] | ||
QEDIIRNIARHLAQVGDSMDR [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for QEDIIRNIARHLAQVGDSMDR. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of QEDIIRNIARHLAQVGDSMDR through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [47] | ||
TW-37 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for TW-37. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TW-37 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [50] | ||
WL-276 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for WL-276. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of WL-276 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [51] | ||
ABT-737 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Apoptosis regulator Bcl-2 (BCL-2) is a therapeutic target for ABT-737. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABT-737 through regulating the expression of Apoptosis regulator Bcl-2 (BCL-2). | [25], [52] | ||
Aromatase (CYP19A1)
Aminoglutethimide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Aminoglutethimide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Aminoglutethimide through regulating the expression of Aromatase (CYP19A1). | [53], [54] | ||
Anastrozole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Anastrozole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Anastrozole through regulating the expression of Aromatase (CYP19A1). | [53], [55] | ||
Dehydroepiandrosterone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Dehydroepiandrosterone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dehydroepiandrosterone through regulating the expression of Aromatase (CYP19A1). | [53], [56] | ||
Dihydrotestosterone [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Dihydrotestosterone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dihydrotestosterone through regulating the expression of Aromatase (CYP19A1). | [53], [57] | ||
Exemestane [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Exemestane. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Exemestane through regulating the expression of Aromatase (CYP19A1). | [53], [58] | ||
FADROZOLE [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for FADROZOLE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FADROZOLE through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
Letrozole [Approved]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Letrozole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Letrozole through regulating the expression of Aromatase (CYP19A1). | [53], [60] | ||
Aromatase (CYP19A1) is a therapeutic target for Letrozole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Letrozole through regulating the expression of Aromatase (CYP19A1). | [53], [61] | |||
Levomethadyl acetate hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Levomethadyl acetate hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Levomethadyl acetate hydrochloride through regulating the expression of Aromatase (CYP19A1). | [53], [62] | ||
Methadone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Methadone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Methadone through regulating the expression of Aromatase (CYP19A1). | [53], [63] | ||
Nandrolone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Nandrolone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nandrolone through regulating the expression of Aromatase (CYP19A1). | [53], [64] | ||
Testolactone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Testolactone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testolactone through regulating the expression of Aromatase (CYP19A1). | [53], [58] | ||
Testosterone cypionate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Testosterone cypionate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testosterone cypionate through regulating the expression of Aromatase (CYP19A1). | [53], [65] | ||
LIAROZOLE [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for LIAROZOLE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LIAROZOLE through regulating the expression of Aromatase (CYP19A1). | [53], [66] | ||
BGS-649 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for BGS-649. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BGS-649 through regulating the expression of Aromatase (CYP19A1). | [53], [67] | ||
Coumate [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Coumate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Coumate through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
Naringenin [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Naringenin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Naringenin through regulating the expression of Aromatase (CYP19A1). | [53], [68] | ||
(2S)-5,7,2',4'-tetrahydroxyflavanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for (2S)-5,7,2',4'-tetrahydroxyflavanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2S)-5,7,2',4'-tetrahydroxyflavanone through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
(2S)-abyssinone II [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for (2S)-abyssinone II. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2S)-abyssinone II through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
(2S)-euchrenone a7 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for (2S)-euchrenone a7. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2S)-euchrenone a7 through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
1-(1-Benzyl-2-biphenyl-4-yl-ethyl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(1-Benzyl-2-biphenyl-4-yl-ethyl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(1-Benzyl-2-biphenyl-4-yl-ethyl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [70] | ||
1-(2-(benzo[b]thiophen-4-yl)ethyl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(2-(benzo[b]thiophen-4-yl)ethyl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(2-(benzo[b]thiophen-4-yl)ethyl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
1-(2-phenoxybenzyl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(2-phenoxybenzyl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(2-phenoxybenzyl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
1-(3-(4-fluorophenyl)propyl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(3-(4-fluorophenyl)propyl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(3-(4-fluorophenyl)propyl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
1-(3-Methoxy-naphthalen-2-yl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(3-Methoxy-naphthalen-2-yl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(3-Methoxy-naphthalen-2-yl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [73] | ||
1-(4-Aminophenyl)-2-(1H-imidazol-1-yl)ethanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(4-Aminophenyl)-2-(1H-imidazol-1-yl)ethanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(4-Aminophenyl)-2-(1H-imidazol-1-yl)ethanone through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
1-(4-Cyanobenzyl)-5-methyl-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(4-Cyanobenzyl)-5-methyl-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(4-Cyanobenzyl)-5-methyl-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
1-(4-nitro-2-phenoxybenzyl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(4-nitro-2-phenoxybenzyl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(4-nitro-2-phenoxybenzyl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
1-(4-Nitro-2-phenylsulfanylbenzyl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(4-Nitro-2-phenylsulfanylbenzyl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(4-Nitro-2-phenylsulfanylbenzyl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [75] | ||
1-(9-phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(9-phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(9-phenyl-9H-fluoren-9-yl)-1H-1,2,4-triazole through regulating the expression of Aromatase (CYP19A1). | [53], [76] | ||
1-(9-Phenyl-9H-fluoren-9-yl)1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(9-Phenyl-9H-fluoren-9-yl)1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(9-Phenyl-9H-fluoren-9-yl)1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
1-(9H-fluoren-9-yl)-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(9H-fluoren-9-yl)-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(9H-fluoren-9-yl)-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
1-(biphenyl-3-ylmethyl)-1H-1,2,4-triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-(biphenyl-3-ylmethyl)-1H-1,2,4-triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(biphenyl-3-ylmethyl)-1H-1,2,4-triazole through regulating the expression of Aromatase (CYP19A1). | [53], [77] | ||
1-Bromo-4-imidazol-1-ylmethyl-xanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-Bromo-4-imidazol-1-ylmethyl-xanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Bromo-4-imidazol-1-ylmethyl-xanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
1-Ethyl-5-(imidazol-1-yl-phenyl-methyl)-1H-indole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-Ethyl-5-(imidazol-1-yl-phenyl-methyl)-1H-indole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Ethyl-5-(imidazol-1-yl-phenyl-methyl)-1H-indole through regulating the expression of Aromatase (CYP19A1). | [53], [78] | ||
1-Imidazol-1-ylmethyl-4-nitro-xanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-Imidazol-1-ylmethyl-4-nitro-xanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Imidazol-1-ylmethyl-4-nitro-xanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [79] | ||
1-Imidazol-1-ylmethylxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-Imidazol-1-ylmethylxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Imidazol-1-ylmethylxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
1-Naphthalen-2-yl-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-Naphthalen-2-yl-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Naphthalen-2-yl-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [80] | ||
1-[(7-Fluoronaphth-2-yl)methyl]-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 1-[(7-Fluoronaphth-2-yl)methyl]-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-[(7-Fluoronaphth-2-yl)methyl]-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
10-EPI-8-DEOXY-CUMAMBRIN B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 10-EPI-8-DEOXY-CUMAMBRIN B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 10-EPI-8-DEOXY-CUMAMBRIN B through regulating the expression of Aromatase (CYP19A1). | [53], [81] | ||
11BETA,13-DIHYDRO-10-EPI-8-DEOXYCUMAM-BRIN B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 11BETA,13-DIHYDRO-10-EPI-8-DEOXYCUMAM-BRIN B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 11BETA,13-DIHYDRO-10-EPI-8-DEOXYCUMAM-BRIN B through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
2,3,4-Trimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2,3,4-Trimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,3,4-Trimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2,3,5-Trimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2,3,5-Trimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,3,5-Trimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2,3-Dimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2,3-Dimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,3-Dimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2,4-Dimethoxy-3'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2,4-Dimethoxy-3'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,4-Dimethoxy-3'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2,4-Dimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2,4-Dimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,4-Dimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2,5-Dimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2,5-Dimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,5-Dimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
2-(3-hydroxyphenyl)-7-methoxychroman-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-(3-hydroxyphenyl)-7-methoxychroman-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(3-hydroxyphenyl)-7-methoxychroman-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
2-(4-hydroxyphenyl)-7-methoxychroman-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-(4-hydroxyphenyl)-7-methoxychroman-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(4-hydroxyphenyl)-7-methoxychroman-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [83] | ||
2-Imidazol-1-yl-7-methoxy-3-phenyl-chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-Imidazol-1-yl-7-methoxy-3-phenyl-chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Imidazol-1-yl-7-methoxy-3-phenyl-chromen-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [77] | ||
2-Imidazol-1-ylmethylxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-Imidazol-1-ylmethylxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Imidazol-1-ylmethylxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [84] | ||
2-phenyl-2,3-dihydrobenzo[h]chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-phenyl-2,3-dihydrobenzo[h]chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-phenyl-2,3-dihydrobenzo[h]chromen-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [85] | ||
2-Phenyl-3-pyridin-4-ylmethylene-chroman-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-Phenyl-3-pyridin-4-ylmethylene-chroman-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Phenyl-3-pyridin-4-ylmethylene-chroman-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [83] | ||
2-Phenyl-4-[1,2,4]triazol-1-yl-chroman-7-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 2-Phenyl-4-[1,2,4]triazol-1-yl-chroman-7-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Phenyl-4-[1,2,4]triazol-1-yl-chroman-7-ol through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
3,4'-(Ethane-1,2-diyl)dibenzenamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,4'-(Ethane-1,2-diyl)dibenzenamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4'-(Ethane-1,2-diyl)dibenzenamine through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,4,5-Trimethoxy-3'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,4,5-Trimethoxy-3'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4,5-Trimethoxy-3'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,4,5-Trimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,4,5-Trimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4,5-Trimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,4-bis(3,4-dimethoxyphenyl)furan-2(5H)-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,4-bis(3,4-dimethoxyphenyl)furan-2(5H)-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-bis(3,4-dimethoxyphenyl)furan-2(5H)-one through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
3,4-Dimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,4-Dimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-Dimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,5-Diacetoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,5-Diacetoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,5-Diacetoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,5-Diamino-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,5-Diamino-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,5-Diamino-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,5-Dihydroxyl-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,5-Dihydroxyl-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,5-Dihydroxyl-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3,5-Dimethoxy-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3,5-Dimethoxy-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,5-Dimethoxy-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3-((1H-imidazol-1-yl)methyl)-9H-xanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-((1H-imidazol-1-yl)methyl)-9H-xanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-((1H-imidazol-1-yl)methyl)-9H-xanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [86] | ||
3-(1-ethyl-3,4-dihydronaphthalen-2-yl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(1-ethyl-3,4-dihydronaphthalen-2-yl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(1-ethyl-3,4-dihydronaphthalen-2-yl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [87] | ||
3-(1-methyl-3,4-dihydronaphthalen-2-yl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(1-methyl-3,4-dihydronaphthalen-2-yl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(1-methyl-3,4-dihydronaphthalen-2-yl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [87] | ||
3-(2,2-Diphenyl-vinyl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(2,2-Diphenyl-vinyl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(2,2-Diphenyl-vinyl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-(3,4-dihydronaphthalen-2-yl)pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(3,4-dihydronaphthalen-2-yl)pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(3,4-dihydronaphthalen-2-yl)pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
3-(3-methyl-3,4-dihydronaphthalen-2-yl)pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(3-methyl-3,4-dihydronaphthalen-2-yl)pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(3-methyl-3,4-dihydronaphthalen-2-yl)pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [87] | ||
3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
3-(4-Amino-phenyl)-3-butyl-piperidine-2,6-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-butyl-piperidine-2,6-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-butyl-piperidine-2,6-dione through regulating the expression of Aromatase (CYP19A1). | [53], [90] | ||
3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione through regulating the expression of Aromatase (CYP19A1). | [53], [91] | ||
3-(4-Amino-phenyl)-3-heptyl-piperidine-2,6-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-heptyl-piperidine-2,6-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-heptyl-piperidine-2,6-dione through regulating the expression of Aromatase (CYP19A1). | [53], [90] | ||
3-(4-Amino-phenyl)-3-hexyl-piperidine-2,6-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-hexyl-piperidine-2,6-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-hexyl-piperidine-2,6-dione through regulating the expression of Aromatase (CYP19A1). | [53], [92] | ||
3-(4-Amino-phenyl)-3-methyl-pyrrolidine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-methyl-pyrrolidine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-methyl-pyrrolidine-2,5-dione through regulating the expression of Aromatase (CYP19A1). | [53], [75] | ||
3-(4-Amino-phenyl)-3-pentyl-piperidine-2,6-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-pentyl-piperidine-2,6-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-pentyl-piperidine-2,6-dione through regulating the expression of Aromatase (CYP19A1). | [53], [90] | ||
3-(4-Amino-phenyl)-3-propyl-piperidine-2,6-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-3-propyl-piperidine-2,6-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-3-propyl-piperidine-2,6-dione through regulating the expression of Aromatase (CYP19A1). | [53], [90] | ||
3-(4-Amino-phenyl)-pyrrolidine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-Amino-phenyl)-pyrrolidine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Amino-phenyl)-pyrrolidine-2,5-dione through regulating the expression of Aromatase (CYP19A1). | [53], [73] | ||
3-(4-methyl-3,4-dihydronaphthalen-2-yl)pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(4-methyl-3,4-dihydronaphthalen-2-yl)pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-methyl-3,4-dihydronaphthalen-2-yl)pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [87] | ||
3-(5-Bromo-6-methoxy-naphthalen-2-yl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(5-Bromo-6-methoxy-naphthalen-2-yl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(5-Bromo-6-methoxy-naphthalen-2-yl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [80] | ||
3-(5-Chloro-6-methoxy-naphthalen-2-yl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(5-Chloro-6-methoxy-naphthalen-2-yl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(5-Chloro-6-methoxy-naphthalen-2-yl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
3-(6-Ethoxy-naphthalen-2-yl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(6-Ethoxy-naphthalen-2-yl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6-Ethoxy-naphthalen-2-yl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [80] | ||
3-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [87] | ||
3-(6-methoxynaphthalen-2-yl)pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(6-methoxynaphthalen-2-yl)pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6-methoxynaphthalen-2-yl)pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [80] | ||
3-(imidazolylmethyl)-4'-methoxyflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(imidazolylmethyl)-4'-methoxyflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(imidazolylmethyl)-4'-methoxyflavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
3-(imidazolylmethyl)-4'-nitroflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(imidazolylmethyl)-4'-nitroflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(imidazolylmethyl)-4'-nitroflavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
3-(imidazolylmethyl)-7-methoxy-4'-nitroflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(imidazolylmethyl)-7-methoxy-4'-nitroflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(imidazolylmethyl)-7-methoxy-4'-nitroflavone through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
3-(imidazolylmethyl)flavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(imidazolylmethyl)flavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(imidazolylmethyl)flavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
3-(naphthalen-2-yl)pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-(naphthalen-2-yl)pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(naphthalen-2-yl)pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [77] | ||
3-Amino-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Amino-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Amino-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3-Fluoren-9-ylidenemethyl-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Fluoren-9-ylidenemethyl-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Fluoren-9-ylidenemethyl-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol through regulating the expression of Aromatase (CYP19A1). | [53], [81] | ||
3-Indan-(1E)-ylidenemethyl-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Indan-(1E)-ylidenemethyl-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Indan-(1E)-ylidenemethyl-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [93] | ||
3-Indan-(1Z)-ylidenemethyl-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Indan-(1Z)-ylidenemethyl-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Indan-(1Z)-ylidenemethyl-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-Methoxyl-4'-amino-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Methoxyl-4'-amino-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Methoxyl-4'-amino-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3-Nitro-4'-nitro-trans-stilbene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-Nitro-4'-nitro-trans-stilbene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Nitro-4'-nitro-trans-stilbene through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
3-[3-Methyl-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[3-Methyl-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[3-Methyl-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[3-Methyl-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[3-Methyl-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[3-Methyl-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[3-Phenyl-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[3-Phenyl-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[3-Phenyl-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[4-Chloro-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[4-Chloro-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[4-Chloro-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[4-Chloro-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[4-Chloro-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[4-Chloro-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[4-Fluoro-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[4-Fluoro-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[4-Fluoro-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[4-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[4-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[4-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[4-Methyl-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[4-Methyl-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[4-Methyl-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[4-Methyl-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[4-Methyl-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[4-Methyl-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Bromo-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Bromo-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Bromo-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Ethoxy-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Ethoxy-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Ethoxy-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Ethoxy-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Ethoxy-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Ethoxy-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Methoxy-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Methoxy-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Methoxy-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[5-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[5-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[5-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[6-Methoxy-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[6-Methoxy-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[6-Methoxy-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[6-Methyl-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[6-Methyl-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[6-Methyl-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
3-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
3-[7-Methoxy-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 3-[7-Methoxy-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-[7-Methoxy-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol through regulating the expression of Aromatase (CYP19A1). | [53], [81] | ||
4'-(Pyridin-4-ylmethyl)biphenyl-3-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4'-(Pyridin-4-ylmethyl)biphenyl-3-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4'-(Pyridin-4-ylmethyl)biphenyl-3-amine through regulating the expression of Aromatase (CYP19A1). | [53], [94] | ||
4'-bromo-3-(imidazolylmethyl)-7-methoxyflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4'-bromo-3-(imidazolylmethyl)-7-methoxyflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4'-bromo-3-(imidazolylmethyl)-7-methoxyflavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
4'-bromo-3-(imidazolylmethyl)flavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4'-bromo-3-(imidazolylmethyl)flavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4'-bromo-3-(imidazolylmethyl)flavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
4'-cyano-3-(imidazolylmethyl)flavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4'-cyano-3-(imidazolylmethyl)flavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4'-cyano-3-(imidazolylmethyl)flavone through regulating the expression of Aromatase (CYP19A1). | [53], [89] | ||
4-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
4-((1H-imidazol-1-yl)methyl)benzonitrile [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-((1H-imidazol-1-yl)methyl)benzonitrile. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-((1H-imidazol-1-yl)methyl)benzonitrile through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
4-(1-Imidazol-1-yl-vinyl)-benzonitrile [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-(1-Imidazol-1-yl-vinyl)-benzonitrile. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(1-Imidazol-1-yl-vinyl)-benzonitrile through regulating the expression of Aromatase (CYP19A1). | [53], [86] | ||
4-(2,2-Diphenyl-vinyl)-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-(2,2-Diphenyl-vinyl)-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2,2-Diphenyl-vinyl)-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
4-(3,4,5-Trimethoxyphenethyl)aniline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-(3,4,5-Trimethoxyphenethyl)aniline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3,4,5-Trimethoxyphenethyl)aniline through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
4-(3,4-Dimethoxyphenethyl)aniline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-(3,4-Dimethoxyphenethyl)aniline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3,4-Dimethoxyphenethyl)aniline through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
4-(3,5-Dimethoxyphenethyl)benzenamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-(3,5-Dimethoxyphenethyl)benzenamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3,5-Dimethoxyphenethyl)benzenamine through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
4-ANDROSTENE-3-17-DIONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-ANDROSTENE-3-17-DIONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-ANDROSTENE-3-17-DIONE through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-Bromo-1-imidazol-1-ylmethyl-xanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Bromo-1-imidazol-1-ylmethyl-xanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Bromo-1-imidazol-1-ylmethyl-xanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-Fluoren-9-ylidenemethyl-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Fluoren-9-ylidenemethyl-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Fluoren-9-ylidenemethyl-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-Imidazol-1-yl-2-phenyl-chroman-7-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-yl-2-phenyl-chroman-7-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-yl-2-phenyl-chroman-7-ol through regulating the expression of Aromatase (CYP19A1). | [53], [95] | ||
4-Imidazol-1-ylmethyl-1-nitro-xanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-ylmethyl-1-nitro-xanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-ylmethyl-1-nitro-xanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
4-Imidazol-1-ylmethyl-1-nitrothioxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-ylmethyl-1-nitrothioxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-ylmethyl-1-nitrothioxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
4-Imidazol-1-ylmethyl-2-nitroxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-ylmethyl-2-nitroxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-ylmethyl-2-nitroxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
4-Imidazol-1-ylmethyl-3-nitroxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-ylmethyl-3-nitroxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-ylmethyl-3-nitroxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
4-Imidazol-1-ylmethylthioxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-ylmethylthioxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-ylmethylthioxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
4-Imidazol-1-ylmethylxanthen-9-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Imidazol-1-ylmethylxanthen-9-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Imidazol-1-ylmethylxanthen-9-one through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
4-Indan-(1E)-ylidenemethyl-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Indan-(1E)-ylidenemethyl-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Indan-(1E)-ylidenemethyl-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-Indan-(1Z)-ylidenemethyl-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-Indan-(1Z)-ylidenemethyl-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Indan-(1Z)-ylidenemethyl-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[(3'-Hydroxybiphenyl-4-yl)methyl]pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[(3'-Hydroxybiphenyl-4-yl)methyl]pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[(3'-Hydroxybiphenyl-4-yl)methyl]pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [81] | ||
4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [96] | ||
4-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Bromo-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
4-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Chloro-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Chloro-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[5-Methoxy-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Methoxy-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Methoxy-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[5-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[5-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[5-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
4-[6-Methoxy-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[6-Methoxy-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[6-Methoxy-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[6-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[6-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[6-Methoxy-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[6-Methyl-indan-(1E)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[6-Methyl-indan-(1E)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[6-Methyl-indan-(1E)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
4-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 4-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
5-((1H-imidazol-1-yl)methyl)-7,8-dihydroquinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-((1H-imidazol-1-yl)methyl)-7,8-dihydroquinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-((1H-imidazol-1-yl)methyl)-7,8-dihydroquinoline through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
5-(2-(1H-imidazol-1-yl)ethyl)quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-(2-(1H-imidazol-1-yl)ethyl)quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-(2-(1H-imidazol-1-yl)ethyl)quinoline through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
5-Bromo-8-imidazol-1-ylmethyl-chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-Bromo-8-imidazol-1-ylmethyl-chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Bromo-8-imidazol-1-ylmethyl-chromen-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
5-Indan-(1E)-ylidenemethyl-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-Indan-(1E)-ylidenemethyl-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Indan-(1E)-ylidenemethyl-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [92] | ||
5-Indan-(1Z)-ylidenemethyl-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-Indan-(1Z)-ylidenemethyl-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Indan-(1Z)-ylidenemethyl-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [92] | ||
5-Pyridin-3-yl-1,3-dihydro-2H-indol-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-Pyridin-3-yl-1,3-dihydro-2H-indol-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Pyridin-3-yl-1,3-dihydro-2H-indol-2-one through regulating the expression of Aromatase (CYP19A1). | [53], [97] | ||
5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one through regulating the expression of Aromatase (CYP19A1). | [53], [77] | ||
5-[5-Bromo-indan-(1E)-ylidenemethyl]-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-[5-Bromo-indan-(1E)-ylidenemethyl]-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-[5-Bromo-indan-(1E)-ylidenemethyl]-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [92] | ||
5-[5-Bromo-indan-(1Z)-ylidenemethyl]-1H-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-[5-Bromo-indan-(1Z)-ylidenemethyl]-1H-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-[5-Bromo-indan-(1Z)-ylidenemethyl]-1H-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
5-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyrimidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyrimidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-[5-Fluoro-indan-(1E)-ylidenemethyl]-pyrimidine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
5-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyrimidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyrimidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-[5-Fluoro-indan-(1Z)-ylidenemethyl]-pyrimidine through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
5-[5-Methoxy-indan-(1E)-ylidenemethyl]-thiazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-[5-Methoxy-indan-(1E)-ylidenemethyl]-thiazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-[5-Methoxy-indan-(1E)-ylidenemethyl]-thiazole through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
5-[5-Methoxy-indan-(1Z)-ylidenemethyl]-thiazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 5-[5-Methoxy-indan-(1Z)-ylidenemethyl]-thiazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-[5-Methoxy-indan-(1Z)-ylidenemethyl]-thiazole through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
6-((1H-imidazol-1-yl)methyl)-2H-chromene-2-thione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 6-((1H-imidazol-1-yl)methyl)-2H-chromene-2-thione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-((1H-imidazol-1-yl)methyl)-2H-chromene-2-thione through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
6-Imidazol-1-yl-isoquinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 6-Imidazol-1-yl-isoquinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Imidazol-1-yl-isoquinoline through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
7,4'-Dihydroxyflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7,4'-Dihydroxyflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7,4'-Dihydroxyflavone through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
7-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one through regulating the expression of Aromatase (CYP19A1). | [53], [98] | ||
7-((1H-imidazol-1-yl)methyl)-4H-chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-((1H-imidazol-1-yl)methyl)-4H-chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-((1H-imidazol-1-yl)methyl)-4H-chromen-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
7-((1H-imidazol-1-yl)methyl)isoquinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-((1H-imidazol-1-yl)methyl)isoquinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-((1H-imidazol-1-yl)methyl)isoquinoline through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
7-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-(2-(1H-imidazol-1-yl)ethoxy)-2H-chromen-2-one through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
7-hydroxy-2-(3-hydroxyphenyl)chroman-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-hydroxy-2-(3-hydroxyphenyl)chroman-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-hydroxy-2-(3-hydroxyphenyl)chroman-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [83] | ||
7-hydroxy-2-phenylchroman-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-hydroxy-2-phenylchroman-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-hydroxy-2-phenylchroman-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [75] | ||
7-[1,2,4]Triazol-4-ylmethyl-chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 7-[1,2,4]Triazol-4-ylmethyl-chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-[1,2,4]Triazol-4-ylmethyl-chromen-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [75] | ||
8-Imidazol-1-ylmethyl-5-nitro-chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 8-Imidazol-1-ylmethyl-5-nitro-chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-Imidazol-1-ylmethyl-5-nitro-chromen-4-one through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
9-Hydroxy-7,8-benzoflavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for 9-Hydroxy-7,8-benzoflavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-Hydroxy-7,8-benzoflavone through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
ALBANOL A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for ALBANOL A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ALBANOL A through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
ALPHA-NAPHTHOFLAVONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for ALPHA-NAPHTHOFLAVONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ALPHA-NAPHTHOFLAVONE through regulating the expression of Aromatase (CYP19A1). | [53], [80] | ||
ANDROSTENEDONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for ANDROSTENEDONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ANDROSTENEDONE through regulating the expression of Aromatase (CYP19A1). | [53], [90] | ||
APIGENIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for APIGENIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APIGENIN through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
Benzyl-biphenyl-4-ylmethyl-imidazol-1-yl-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Benzyl-biphenyl-4-ylmethyl-imidazol-1-yl-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Benzyl-biphenyl-4-ylmethyl-imidazol-1-yl-amine through regulating the expression of Aromatase (CYP19A1). | [53], [82] | ||
biochanin A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for biochanin A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of biochanin A through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
Broussoflavonol F [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Broussoflavonol F. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Broussoflavonol F through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
CGS-18320B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for CGS-18320B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CGS-18320B through regulating the expression of Aromatase (CYP19A1). | [53], [99] | ||
Chrysin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Chrysin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Chrysin through regulating the expression of Aromatase (CYP19A1). | [53], [88] | ||
DEHYDROLEUCODIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for DEHYDROLEUCODIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DEHYDROLEUCODIN through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
Docosapentaenoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Docosapentaenoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Docosapentaenoic acid through regulating the expression of Aromatase (CYP19A1). | [53], [100] | ||
flavone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for flavone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of flavone through regulating the expression of Aromatase (CYP19A1). | [53], [74] | ||
Gamma-mangostin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Gamma-mangostin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gamma-mangostin through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
GARCINONE D [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for GARCINONE D. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GARCINONE D through regulating the expression of Aromatase (CYP19A1). | [53], [97] | ||
GOSSYPETIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for GOSSYPETIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GOSSYPETIN through regulating the expression of Aromatase (CYP19A1). | [53], [70] | ||
Isogemichalcone C [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Isogemichalcone C. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Isogemichalcone C through regulating the expression of Aromatase (CYP19A1). | [53], [85] | ||
ISOLICOFLAVONOL [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for ISOLICOFLAVONOL. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISOLICOFLAVONOL through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
LIQUIRTIGENIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for LIQUIRTIGENIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LIQUIRTIGENIN through regulating the expression of Aromatase (CYP19A1). | [53], [83] | ||
LUDARTIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for LUDARTIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LUDARTIN through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
MDL-18962 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MDL-18962. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MDL-18962 through regulating the expression of Aromatase (CYP19A1). | [53], [101] | ||
MONODICTYOCHROMONE B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MONODICTYOCHROMONE B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MONODICTYOCHROMONE B through regulating the expression of Aromatase (CYP19A1). | [53], [72] | ||
MORACHALCONE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MORACHALCONE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MORACHALCONE A through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
MR-16089 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MR-16089. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MR-16089 through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
MR-20492 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MR-20492. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MR-20492 through regulating the expression of Aromatase (CYP19A1). | [53], [91] | ||
MR-20494 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MR-20494. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MR-20494 through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
MR-20496 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MR-20496. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MR-20496 through regulating the expression of Aromatase (CYP19A1). | [53], [73] | ||
MR-20814 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MR-20814. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MR-20814 through regulating the expression of Aromatase (CYP19A1). | [53], [83] | ||
N-(2-benzyloxy-4-nitrophenyl)methanesulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for N-(2-benzyloxy-4-nitrophenyl)methanesulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(2-benzyloxy-4-nitrophenyl)methanesulfonamide through regulating the expression of Aromatase (CYP19A1). | [53], [87] | ||
N-(2-hexyloxy-4-nitrophenyl)methanesulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for N-(2-hexyloxy-4-nitrophenyl)methanesulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(2-hexyloxy-4-nitrophenyl)methanesulfonamide through regulating the expression of Aromatase (CYP19A1). | [53], [76] | ||
N-(2-nonyloxy-4-nitrophenyl)methanesulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for N-(2-nonyloxy-4-nitrophenyl)methanesulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(2-nonyloxy-4-nitrophenyl)methanesulfonamide through regulating the expression of Aromatase (CYP19A1). | [53], [76] | ||
N-(2-Propyloxy-4-nitrophenyl)methanesulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for N-(2-Propyloxy-4-nitrophenyl)methanesulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(2-Propyloxy-4-nitrophenyl)methanesulfonamide through regulating the expression of Aromatase (CYP19A1). | [53], [102] | ||
N-[2-(4'-Nitrophenyl)ethyl]-imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for N-[2-(4'-Nitrophenyl)ethyl]-imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-[2-(4'-Nitrophenyl)ethyl]-imidazole through regulating the expression of Aromatase (CYP19A1). | [53], [59] | ||
NSC-122427 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-122427. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-122427 through regulating the expression of Aromatase (CYP19A1). | [53], [84] | ||
NSC-12999 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-12999. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-12999 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-131736 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-131736. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-131736 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-289311 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-289311. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-289311 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-356483 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-356483. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-356483 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-356781 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-356781. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-356781 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-368272 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-368272. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-368272 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-368280 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-368280. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-368280 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-369087 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-369087. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-369087 through regulating the expression of Aromatase (CYP19A1). | [53], [81] | ||
NSC-613604 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-613604. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-613604 through regulating the expression of Aromatase (CYP19A1). | [53], [84] | ||
NSC-625409 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-625409. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-625409 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-666292 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-666292. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-666292 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-683634 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-683634. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-683634 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-75308 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-75308. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-75308 through regulating the expression of Aromatase (CYP19A1). | [53], [71] | ||
NSC-93358 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-93358. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-93358 through regulating the expression of Aromatase (CYP19A1). | [53], [67] | ||
NSC-94258 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-94258. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-94258 through regulating the expression of Aromatase (CYP19A1). | [53], [69] | ||
NSC-94891 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NSC-94891. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-94891 through regulating the expression of Aromatase (CYP19A1). | [53], [84] | ||
Org-33201 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Org-33201. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Org-33201 through regulating the expression of Aromatase (CYP19A1). | [53], [103] | ||
FINROZOLE [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for FINROZOLE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FINROZOLE through regulating the expression of Aromatase (CYP19A1). | [53], [104] | ||
FORMESTANE [Withdrawn from market]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for FORMESTANE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FORMESTANE through regulating the expression of Aromatase (CYP19A1). | [53], [105] | ||
MINAMESTANE [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for MINAMESTANE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MINAMESTANE through regulating the expression of Aromatase (CYP19A1). | [53], [106] | ||
NKS-01 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for NKS-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NKS-01 through regulating the expression of Aromatase (CYP19A1). | [53], [107] | ||
Rogletimide [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Rogletimide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rogletimide through regulating the expression of Aromatase (CYP19A1). | [53], [108] | ||
VOROZOLE [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for VOROZOLE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VOROZOLE through regulating the expression of Aromatase (CYP19A1). | [53], [109] | ||
YM-511 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for YM-511. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of YM-511 through regulating the expression of Aromatase (CYP19A1). | [53], [110] | ||
Beta-catenin (CTNNB1)
Recombinant human endostatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Beta-catenin (CTNNB1) is a therapeutic target for Recombinant human endostatin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Recombinant human endostatin through regulating the expression of Beta-catenin (CTNNB1). | [111], [112] | ||
C 82 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Beta-catenin (CTNNB1) is a therapeutic target for C 82. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C 82 through regulating the expression of Beta-catenin (CTNNB1). | [111], [113] | ||
CEQ-508 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Beta-catenin (CTNNB1) is a therapeutic target for CEQ-508. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CEQ-508 through regulating the expression of Beta-catenin (CTNNB1). | [111], [114] | ||
C-X-C chemokine receptor type 4 (CXCR4)
Plerixafor [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Plerixafor. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Plerixafor through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [116] | ||
AMD-070 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for AMD-070. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMD-070 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [117] | ||
Balixafortide [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Balixafortide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Balixafortide through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [28], [115] | ||
BL-8040 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for BL-8040. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BL-8040 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [118] | ||
Ulocuplumab [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Ulocuplumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ulocuplumab through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [119] | ||
CTCE-9908 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for CTCE-9908. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CTCE-9908 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [38], [115] | ||
POL-6326 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for POL-6326. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of POL-6326 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [120] | ||
TG-0054 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for TG-0054. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TG-0054 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [121] | ||
USL311 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for USL311. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of USL311 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [122] | ||
ALX-0651 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for ALX-0651. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ALX-0651 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [123] | ||
BMS-936564 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for BMS-936564. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-936564 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [118] | ||
CTCE-0214 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for CTCE-0214. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CTCE-0214 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [124] | ||
GMI-1359 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for GMI-1359. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GMI-1359 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [125] | ||
LY2624587 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for LY2624587. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY2624587 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [126] | ||
MSX-122 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for MSX-122. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MSX-122 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [127] | ||
PF-06747143 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for PF-06747143. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-06747143 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [128] | ||
MAb173 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for MAb173. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MAb173 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [129] | ||
AT-009 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for AT-009. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AT-009 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
ATI-2341 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for ATI-2341. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ATI-2341 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
CTCE-0324 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for CTCE-0324. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CTCE-0324 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [131] | ||
CX-02 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for CX-02. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CX-02 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
CXCL8 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for CXCL8. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CXCL8 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [132] | ||
CXCR4 gene disrupted T cells [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for CXCR4 gene disrupted T cells. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CXCR4 gene disrupted T cells through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
Cyclo(-D-Ala-D-Arg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Ala-D-Arg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Ala-D-Arg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-MeTyr-D-Arg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-MeTyr-D-Arg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-MeTyr-D-Arg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-MeTyr-L-Arg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-MeTyr-L-Arg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-MeTyr-L-Arg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-Arg-Arg-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-Arg-Arg-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-Arg-Arg-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [134] | ||
Cyclo(-D-Tyr-D-Ala-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Ala-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Ala-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-MeNal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-MeNal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-MeNal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-beta-Ala-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-beta-Ala-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-beta-Ala-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-D-Ala-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-D-Ala-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-D-Ala-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [135] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-L-Ala-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-L-Ala-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-L-Ala-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-L-Pic-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-L-Pic-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-L-Pic-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-Sar-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-Sar-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-Arg-L-Nal-Sar-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-Arg-L-MeArg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-Arg-L-MeArg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-Arg-L-MeArg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-D-MeArg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-D-MeArg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-D-MeArg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Ala-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Ala-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Ala-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-Arg-L-Ala-Sar-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-Arg-L-Ala-Sar-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-Arg-L-Ala-Sar-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-Arg-L-MeNal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-Arg-L-MeNal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-Arg-L-MeNal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-beta-Ala-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-beta-Ala-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-beta-Ala-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-D-Ala-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-D-Ala-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-D-Ala-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-L-Ala-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-L-Ala-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-Arg-L-Nal-L-Ala-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-Arg-L-MeArg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-Arg-L-MeArg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-Arg-L-MeArg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
Cyclo(-D-Tyr-L-MeArg-L-Arg-L-Nal-Gly-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Cyclo(-D-Tyr-L-MeArg-L-Arg-L-Nal-Gly-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclo(-D-Tyr-L-MeArg-L-Arg-L-Nal-Gly-) through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
GSK-812397 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for GSK-812397. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-812397 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
isothiourea-1a [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for isothiourea-1a. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of isothiourea-1a through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [131] | ||
isothiourea-1t [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for isothiourea-1t. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of isothiourea-1t through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [136] | ||
KUR-CXCR4 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for KUR-CXCR4. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KUR-CXCR4 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
LP-0067 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for LP-0067. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LP-0067 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
NB-325 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for NB-325. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NB-325 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
ND-401 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for ND-401. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ND-401 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [130] | ||
T134 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for T134. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of T134 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [136] | ||
T140 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for T140. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of T140 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [136] | ||
T22 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for T22. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of T22 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [137] | ||
TN-14003 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for TN-14003. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TN-14003 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [133] | ||
viral macrophage inflammatory protein-II [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for viral macrophage inflammatory protein-II. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of viral macrophage inflammatory protein-II through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [138] | ||
Garnocestim [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for Garnocestim. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Garnocestim through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [139] | ||
KRH-2731 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for KRH-2731. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KRH-2731 through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [140] | ||
SURADISTA [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | C-X-C chemokine receptor type 4 (CXCR4) is a therapeutic target for SURADISTA. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SURADISTA through regulating the expression of C-X-C chemokine receptor type 4 (CXCR4). | [115], [141] | ||
cAMP-dependent protein kinase A type I (PRKAR1A)
5-(2-methylpiperazin-1-ylsulfonyl)isoquinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for 5-(2-methylpiperazin-1-ylsulfonyl)isoquinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-(2-methylpiperazin-1-ylsulfonyl)isoquinoline through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [143] | ||
AdcAhxArg4Lys(biotin)-PEG-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdcAhxArg4Lys(biotin)-PEG-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdcAhxArg4Lys(biotin)-PEG-OMe through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [144] | ||
AdcAhxArg4Lys-PEGOMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdcAhxArg4Lys-PEGOMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdcAhxArg4Lys-PEGOMe through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdcAhxArg4NH(CH2)6NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdcAhxArg4NH(CH2)6NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdcAhxArg4NH(CH2)6NH2 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [144] | ||
AdcAhxArg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdcAhxArg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdcAhxArg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [144] | ||
AdoC(Ahx)Arg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(Ahx)Arg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(Ahx)Arg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoC(Aoc)Arg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(Aoc)Arg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(Aoc)Arg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoC(Aun)Arg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(Aun)Arg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(Aun)Arg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoC(beta-Ala)2AlaArg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(beta-Ala)2AlaArg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(beta-Ala)2AlaArg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [146] | ||
AdoC(beta-Ala)Arg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(beta-Ala)Arg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(beta-Ala)Arg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoC(betaAsp)2AlaArg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(betaAsp)2AlaArg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(betaAsp)2AlaArg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoC(Dpr)2AlaArg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(Dpr)2AlaArg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(Dpr)2AlaArg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoC(GABA)Arg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoC(GABA)Arg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoC(GABA)Arg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
AdoCGlyArg6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for AdoCGlyArg6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AdoCGlyArg6 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [145] | ||
Cyclic Guanosine Monophosphate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for Cyclic Guanosine Monophosphate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclic Guanosine Monophosphate through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [147] | ||
RO-316233 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for RO-316233. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RO-316233 through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [144] | ||
Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [148] | ||
[3H]cAMP [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | cAMP-dependent protein kinase A type I (PRKAR1A) is a therapeutic target for [3H]cAMP. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]cAMP through regulating the expression of cAMP-dependent protein kinase A type I (PRKAR1A). | [142], [148] | ||
Cathepsin B (CTSB)
CA-074Me [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for CA-074Me. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CA-074Me through regulating the expression of Cathepsin B (CTSB). | [149], [150] | ||
L-006235-1 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for L-006235-1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-006235-1 through regulating the expression of Cathepsin B (CTSB). | [149], [151] | ||
SD1002 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for SD1002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SD1002 through regulating the expression of Cathepsin B (CTSB). | [149], [150] | ||
SD1003 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for SD1003. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SD1003 through regulating the expression of Cathepsin B (CTSB). | [149], [150] | ||
Z-Phe-Ala-diazomethylketone [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Phe-Ala-diazomethylketone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Phe-Ala-diazomethylketone through regulating the expression of Cathepsin B (CTSB). | [149], [152] | ||
(S)-1-benzylcyclopentyl 1-oxohexan-2-ylcarbamate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for (S)-1-benzylcyclopentyl 1-oxohexan-2-ylcarbamate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (S)-1-benzylcyclopentyl 1-oxohexan-2-ylcarbamate through regulating the expression of Cathepsin B (CTSB). | [149], [153] | ||
1-(phenyl(p-tolyl)methylene)thiosemicarbazide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for 1-(phenyl(p-tolyl)methylene)thiosemicarbazide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(phenyl(p-tolyl)methylene)thiosemicarbazide through regulating the expression of Cathepsin B (CTSB). | [149], [154] | ||
2-Aminoethanimidic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for 2-Aminoethanimidic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Aminoethanimidic Acid through regulating the expression of Cathepsin B (CTSB). | [148], [149] | ||
2-Pyridinethiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for 2-Pyridinethiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Pyridinethiol through regulating the expression of Cathepsin B (CTSB). | [148], [149] | ||
3-Amino-4-Oxybenzyl-2-Butanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for 3-Amino-4-Oxybenzyl-2-Butanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Amino-4-Oxybenzyl-2-Butanone through regulating the expression of Cathepsin B (CTSB). | [148], [149] | ||
3-Methylphenylalanine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for 3-Methylphenylalanine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Methylphenylalanine through regulating the expression of Cathepsin B (CTSB). | [149], [155] | ||
Ac-hPhe-Leu-Ala-LeuVSMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Ac-hPhe-Leu-Ala-LeuVSMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-hPhe-Leu-Ala-LeuVSMe through regulating the expression of Cathepsin B (CTSB). | [149], [156] | ||
Ac-hPhe-Leu-Phe-LeuVSMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Ac-hPhe-Leu-Phe-LeuVSMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-hPhe-Leu-Phe-LeuVSMe through regulating the expression of Cathepsin B (CTSB). | [149], [153] | ||
Bis(3-bromophenyl)(4-hydroxy)thiosemicarbazone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Bis(3-bromophenyl)(4-hydroxy)thiosemicarbazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(3-bromophenyl)(4-hydroxy)thiosemicarbazone through regulating the expression of Cathepsin B (CTSB). | [149], [157] | ||
Cbz-Ile-Leu-Ala-LeuVSMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Cbz-Ile-Leu-Ala-LeuVSMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cbz-Ile-Leu-Ala-LeuVSMe through regulating the expression of Cathepsin B (CTSB). | [149], [153] | ||
Cbz-Ile-t-ButylhomoGlu-Ala-LeuVSMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Cbz-Ile-t-ButylhomoGlu-Ala-LeuVSMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cbz-Ile-t-ButylhomoGlu-Ala-LeuVSMe through regulating the expression of Cathepsin B (CTSB). | [149], [153] | ||
Diphenylacetic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Diphenylacetic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Diphenylacetic Acid through regulating the expression of Cathepsin B (CTSB). | [149], [158] | ||
GNF-PF-5434 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for GNF-PF-5434. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GNF-PF-5434 through regulating the expression of Cathepsin B (CTSB). | [149], [159] | ||
Gold trichloride sodium chloride [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Gold trichloride sodium chloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gold trichloride sodium chloride through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
L-873724 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for L-873724. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-873724 through regulating the expression of Cathepsin B (CTSB). | [149], [161] | ||
PTosyl-Glu(OtBu)-Ala-LeuVSMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for PTosyl-Glu(OtBu)-Ala-LeuVSMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PTosyl-Glu(OtBu)-Ala-LeuVSMe through regulating the expression of Cathepsin B (CTSB). | [149], [153] | ||
Z-Ala-Leu-His-Agly-Ile-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Ala-Leu-His-Agly-Ile-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Ala-Leu-His-Agly-Ile-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Ala-Leu-lle-Agly-Ile-Val-NHBzl [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Ala-Leu-lle-Agly-Ile-Val-NHBzl. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Ala-Leu-lle-Agly-Ile-Val-NHBzl through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Ala-Leu-lle-Agly-Ile-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Ala-Leu-lle-Agly-Ile-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Ala-Leu-lle-Agly-Ile-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Ala-Leu-Nal-Agly-Ile-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Ala-Leu-Nal-Agly-Ile-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Ala-Leu-Nal-Agly-Ile-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Ala-Leu-Phe-Agly-Ile-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Ala-Leu-Phe-Agly-Ile-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Ala-Leu-Phe-Agly-Ile-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Ala-Leu-Tyr(Me)-Agly-Ile-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Ala-Leu-Tyr(Me)-Agly-Ile-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Ala-Leu-Tyr(Me)-Agly-Ile-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Arg-Leu-Val-Agly-Ala-Gly-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Arg-Leu-Val-Agly-Ala-Gly-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Arg-Leu-Val-Agly-Ala-Gly-NH2 through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Arg-Leu-Val-Agly-Ile-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Arg-Leu-Val-Agly-Ile-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Arg-Leu-Val-Agly-Ile-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [148], [149] | ||
Z-Arg-Leu-Val-Agly-Ile-Val-Trp-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Arg-Leu-Val-Agly-Ile-Val-Trp-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Arg-Leu-Val-Agly-Ile-Val-Trp-NH2 through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Arg-Leu-Val-Agly-Ileu-Val-OMe [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Arg-Leu-Val-Agly-Ileu-Val-OMe. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Arg-Leu-Val-Agly-Ileu-Val-OMe through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Arg-Leu-Val-Agly-Trp-Val-Ala-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Arg-Leu-Val-Agly-Trp-Val-Ala-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Arg-Leu-Val-Agly-Trp-Val-Ala-NH2 through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
Z-Arg-Leu-Val-Agly-Val-Ala-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-Arg-Leu-Val-Agly-Val-Ala-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-Arg-Leu-Val-Agly-Val-Ala-NH2 through regulating the expression of Cathepsin B (CTSB). | [149], [162] | ||
Z-leu-Val-Agly-Val-OBzl [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for Z-leu-Val-Agly-Val-OBzl. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Z-leu-Val-Agly-Val-OBzl through regulating the expression of Cathepsin B (CTSB). | [149], [160] | ||
[(3-Bromophenyl)-p-tolyl-ketone]thiosemicarbazone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cathepsin B (CTSB) is a therapeutic target for [(3-Bromophenyl)-p-tolyl-ketone]thiosemicarbazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [(3-Bromophenyl)-p-tolyl-ketone]thiosemicarbazone through regulating the expression of Cathepsin B (CTSB). | [149], [163] | ||
CEBPA messenger RNA (CEBPA mRNA)
MTL-CEPBA [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | CEBPA messenger RNA (CEBPA mRNA) is a therapeutic target for MTL-CEPBA. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MTL-CEPBA through regulating the expression of CEBPA messenger RNA (CEBPA mRNA). | [24], [164] | ||
Cellular tumor antigen p53 (TP53)
Contusugene ladenovec [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Contusugene ladenovec. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Contusugene ladenovec through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [166] | ||
QPI-1002 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for QPI-1002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of QPI-1002 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [167] | ||
Thymoquinone [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Thymoquinone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Thymoquinone through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [168] | ||
Ad-p53 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Ad-p53. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ad-p53 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [169] | ||
ALT-801 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for ALT-801. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ALT-801 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [170] | ||
APG-115 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for APG-115. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APG-115 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [171] | ||
APR-246 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for APR-246. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APR-246 through regulating the expression of Cellular tumor antigen p53 (TP53). | [78], [165] | ||
Cenersen [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Cenersen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cenersen through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [172] | ||
INGN-225 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for INGN-225. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INGN-225 through regulating the expression of Cellular tumor antigen p53 (TP53). | [38], [165] | ||
ISA-P53-01 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for ISA-P53-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISA-P53-01 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [173] | ||
Kevetrin [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Kevetrin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Kevetrin through regulating the expression of Cellular tumor antigen p53 (TP53). | [22], [165] | ||
OPI-1002 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for OPI-1002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OPI-1002 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [174] | ||
SGT-53 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for SGT-53. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SGT-53 through regulating the expression of Cellular tumor antigen p53 (TP53). | [38], [165] | ||
CGM097 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for CGM097. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CGM097 through regulating the expression of Cellular tumor antigen p53 (TP53). | [38], [165] | ||
COTI-2 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for COTI-2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of COTI-2 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [175] | ||
Dendritic cell vaccine [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Dendritic cell vaccine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dendritic cell vaccine through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [176] | ||
HDM201 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for HDM201. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HDM201 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [177] | ||
ONYX-015 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for ONYX-015. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ONYX-015 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [178] | ||
SAR-405838 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for SAR-405838. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SAR-405838 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [166] | ||
1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [179] | ||
AHL [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for AHL. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AHL through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [180] | ||
NU-8231 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for NU-8231. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NU-8231 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [181] | ||
NUTLIN-3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for NUTLIN-3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NUTLIN-3 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [182] | ||
INGN-234 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for INGN-234. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INGN-234 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [183] | ||
Pifithrin-alpha [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for Pifithrin-alpha. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pifithrin-alpha through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [184] | ||
TAR-1 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cellular tumor antigen p53 (TP53) is a therapeutic target for TAR-1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAR-1 through regulating the expression of Cellular tumor antigen p53 (TP53). | [165], [185] | ||
Cyclin A2 (CCNA2)
2,5-dichloro-N-p-tolylthiophene-3-sulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 2,5-dichloro-N-p-tolylthiophene-3-sulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,5-dichloro-N-p-tolylthiophene-3-sulfonamide through regulating the expression of Cyclin A2 (CCNA2). | [186], [187] | ||
4-(phenyldiazenyl)-1H-pyrazole-3,5-diamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 4-(phenyldiazenyl)-1H-pyrazole-3,5-diamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(phenyldiazenyl)-1H-pyrazole-3,5-diamine through regulating the expression of Cyclin A2 (CCNA2). | [186], [188] | ||
6-(3-Amino-benzyloxy)-9H-purin-2-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 6-(3-Amino-benzyloxy)-9H-purin-2-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(3-Amino-benzyloxy)-9H-purin-2-ylamine through regulating the expression of Cyclin A2 (CCNA2). | [186], [189] | ||
6-(3-Methyl-benzyloxy)-9H-purin-2-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 6-(3-Methyl-benzyloxy)-9H-purin-2-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(3-Methyl-benzyloxy)-9H-purin-2-ylamine through regulating the expression of Cyclin A2 (CCNA2). | [186], [190] | ||
6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine through regulating the expression of Cyclin A2 (CCNA2). | [186], [190] | ||
6-Cyclohexylmethoxy-pyrimidine-2,4,5-triamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 6-Cyclohexylmethoxy-pyrimidine-2,4,5-triamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Cyclohexylmethoxy-pyrimidine-2,4,5-triamine through regulating the expression of Cyclin A2 (CCNA2). | [186], [191] | ||
6-O-Cyclohexylmethyl Guanine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for 6-O-Cyclohexylmethyl Guanine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-O-Cyclohexylmethyl Guanine through regulating the expression of Cyclin A2 (CCNA2). | [186], [190] | ||
aloisine A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for aloisine A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of aloisine A through regulating the expression of Cyclin A2 (CCNA2). | [186], [192] | ||
GW-8510 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for GW-8510. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-8510 through regulating the expression of Cyclin A2 (CCNA2). | [186], [193] | ||
MERIOLIN 1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 1 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
MERIOLIN 2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 2 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
MERIOLIN 3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 3 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
MERIOLIN 4 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 4. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 4 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
MERIOLIN 5 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 5. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 5 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
MERIOLIN 6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 6 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
MERIOLIN 7 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 7. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 7 through regulating the expression of Cyclin A2 (CCNA2). | [186], [195] | ||
MERIOLIN 8 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for MERIOLIN 8. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 8 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
NU-6027 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for NU-6027. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NU-6027 through regulating the expression of Cyclin A2 (CCNA2). | [186], [194] | ||
Purvalanol A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for Purvalanol A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Purvalanol A through regulating the expression of Cyclin A2 (CCNA2). | [186], [196] | ||
RESCOVITINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for RESCOVITINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RESCOVITINE through regulating the expression of Cyclin A2 (CCNA2). | [186], [197] | ||
PD-0183812 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin A2 (CCNA2) is a therapeutic target for PD-0183812. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0183812 through regulating the expression of Cyclin A2 (CCNA2). | [186], [198] | ||
Cyclin-dependent kinase 2 (CDK2)
PHA848125 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PHA848125. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PHA848125 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
Ro 31-7453 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Ro 31-7453. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro 31-7453 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [200] | ||
Roscovitine [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Roscovitine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Roscovitine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [201] | ||
TG02 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for TG02. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TG02 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [202] | ||
AG-024322 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for AG-024322. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AG-024322 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [203] | ||
AT7519 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for AT7519. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AT7519 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [204] | ||
AZD-5438 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for AZD-5438. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD-5438 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [205] | ||
CYC065 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for CYC065. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CYC065 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [206] | ||
FN-1501 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for FN-1501. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FN-1501 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [207] | ||
PF-07104091 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PF-07104091. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-07104091 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [208] | ||
PHA-793887 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PHA-793887. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PHA-793887 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [209] | ||
RGB-286638 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for RGB-286638. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RGB-286638 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [202] | ||
SNS-032 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for SNS-032. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SNS-032 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [38], [186] | ||
INOC-005 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for INOC-005. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INOC-005 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
L-751250 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for L-751250. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-751250 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [202] | ||
1-Amino-6-Cyclohex-3-Enylmethyloxypurine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 1-Amino-6-Cyclohex-3-Enylmethyloxypurine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Amino-6-Cyclohex-3-Enylmethyloxypurine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
10Z-Hymenialdisine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 10Z-Hymenialdisine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 10Z-Hymenialdisine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
2-Amino-6-Chloropyrazine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 2-Amino-6-Chloropyrazine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Amino-6-Chloropyrazine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [210] | ||
3,4-diphenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 3,4-diphenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-diphenyl-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [211] | ||
3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [212] | ||
3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [210] | ||
4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
5-hydroxynaphthalene-1-sulfonamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 5-hydroxynaphthalene-1-sulfonamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-hydroxynaphthalene-1-sulfonamide through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
6-(3-Amino-benzyloxy)-9H-purin-2-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-(3-Amino-benzyloxy)-9H-purin-2-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(3-Amino-benzyloxy)-9H-purin-2-ylamine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [189] | ||
6-(3-Methyl-benzyloxy)-9H-purin-2-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-(3-Methyl-benzyloxy)-9H-purin-2-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(3-Methyl-benzyloxy)-9H-purin-2-ylamine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [190] | ||
6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [190] | ||
6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
6-Cyclohexylmethoxy-pyrimidine-2,4,5-triamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-Cyclohexylmethoxy-pyrimidine-2,4,5-triamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Cyclohexylmethoxy-pyrimidine-2,4,5-triamine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [190] | ||
6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
6-O-Cyclohexylmethyl Guanine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 6-O-Cyclohexylmethyl Guanine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-O-Cyclohexylmethyl Guanine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
9-Nitropaullone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for 9-Nitropaullone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-Nitropaullone through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
aloisine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for aloisine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of aloisine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [191] | ||
aloisine A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for aloisine A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of aloisine A through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [213] | ||
aminopurvalanol A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for aminopurvalanol A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of aminopurvalanol A through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [214] | ||
Benzyl-(9-isopropyl-9H-purin-6-yl)-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Benzyl-(9-isopropyl-9H-purin-6-yl)-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Benzyl-(9-isopropyl-9H-purin-6-yl)-amine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
BMS 536924 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for BMS 536924. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS 536924 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [193] | ||
BMS-265246 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for BMS-265246. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-265246 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [215] | ||
BOHEMINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for BOHEMINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BOHEMINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
BX-795 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for BX-795. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BX-795 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [215] | ||
BX-912 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for BX-912. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BX-912 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [216] | ||
Cdk4 inhibitor III [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Cdk4 inhibitor III. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cdk4 inhibitor III through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [217] | ||
CVT-313 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for CVT-313. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CVT-313 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [218] | ||
Double Oxidized Cysteine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Double Oxidized Cysteine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Double Oxidized Cysteine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [217] | ||
GW-8510 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for GW-8510. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-8510 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [193] | ||
Indirubin-3'-monoxime [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Indirubin-3'-monoxime. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Indirubin-3'-monoxime through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
Indirubin-5-sulfonate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Indirubin-5-sulfonate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Indirubin-5-sulfonate through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
JNJ 7706621 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for JNJ 7706621. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of JNJ 7706621 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [210] | ||
K00024 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for K00024. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of K00024 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [219] | ||
Lysine Nz-Carboxylic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Lysine Nz-Carboxylic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lysine Nz-Carboxylic Acid through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
MERIOLIN 1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 1 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [210] | ||
MERIOLIN 2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 2 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
MERIOLIN 3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 3 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
MERIOLIN 4 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 4. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 4 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
MERIOLIN 5 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 5. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 5 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
MERIOLIN 6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 6 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
MERIOLIN 8 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for MERIOLIN 8. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MERIOLIN 8 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [148], [186] | ||
N-(4-amino-5-cyano-6-phenylpyridin-2-yl)acetamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for N-(4-amino-5-cyano-6-phenylpyridin-2-yl)acetamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(4-amino-5-cyano-6-phenylpyridin-2-yl)acetamide through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [220] | ||
N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [155], [186] | ||
N-phenyl-1H-pyrazole-3-carboxamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for N-phenyl-1H-pyrazole-3-carboxamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-phenyl-1H-pyrazole-3-carboxamide through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
NSC-625987 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for NSC-625987. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-625987 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [221] | ||
NU-6027 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for NU-6027. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NU-6027 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [194] | ||
NU-6102 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for NU-6102. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NU-6102 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [195] | ||
NU6140 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for NU6140. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NU6140 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [222] | ||
Oxindole 95 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Oxindole 95. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Oxindole 95 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [199] | ||
PF-228 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PF-228. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-228 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [196] | ||
PHA-690509 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PHA-690509. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PHA-690509 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [223] | ||
PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
Purvalanol A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Purvalanol A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Purvalanol A through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [224] | ||
PYRAZOLOPYRIDAZINE 1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PYRAZOLOPYRIDAZINE 1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PYRAZOLOPYRIDAZINE 1 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [225] | ||
PYRAZOLOPYRIDAZINE 2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PYRAZOLOPYRIDAZINE 2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PYRAZOLOPYRIDAZINE 2 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [226] | ||
RESCOVITINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for RESCOVITINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RESCOVITINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [211] | ||
SCH-546909 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for SCH-546909. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SCH-546909 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [227] | ||
SU9516 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for SU9516. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SU9516 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [225] | ||
TRIAZOLOPYRIMIDINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for TRIAZOLOPYRIMIDINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TRIAZOLOPYRIMIDINE through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [78], [186] | ||
VER-54505 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for VER-54505. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VER-54505 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [223] | ||
BAY 10-00394 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for BAY 10-00394. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BAY 10-00394 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [228] | ||
Olomoucine [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for Olomoucine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Olomoucine through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [229] | ||
PD-0183812 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for PD-0183812. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0183812 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [230] | ||
R547 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for R547. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of R547 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [202] | ||
SCH 727965 [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for SCH 727965. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SCH 727965 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [231] | ||
ZK 304709 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 2 (CDK2) is a therapeutic target for ZK 304709. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZK 304709 through regulating the expression of Cyclin-dependent kinase 2 (CDK2). | [186], [202] | ||
Cyclin-dependent kinase 6 (CDK6)
Apremilast [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Apremilast. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Apremilast through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [166], [232] | ||
LY2835219 [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for LY2835219. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY2835219 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [233] | ||
Palbociclib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Palbociclib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Palbociclib through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [234] | ||
Ribociclib Succinate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Ribociclib Succinate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ribociclib Succinate through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [229], [232] | ||
Trilaciclib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Trilaciclib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Trilaciclib through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [235] | ||
LEE011 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for LEE011. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LEE011 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [236] | ||
FCN-437 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for FCN-437. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FCN-437 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [237] | ||
G1T38 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for G1T38. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of G1T38 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [238] | ||
GLR2007 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for GLR2007. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GLR2007 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [38], [232] | ||
FN-1501 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for FN-1501. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FN-1501 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [239] | ||
G1T28-1 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for G1T28-1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of G1T28-1 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [208], [232] | ||
INOC-005 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for INOC-005. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INOC-005 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [166], [232] | ||
3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [210], [232] | ||
3,4-diphenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for 3,4-diphenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-diphenyl-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [210], [232] | ||
3,7,3',4'-TETRAHYDROXYFLAVONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for 3,7,3',4'-TETRAHYDROXYFLAVONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,7,3',4'-TETRAHYDROXYFLAVONE through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [199], [232] | ||
3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [240] | ||
APIGENIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for APIGENIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APIGENIN through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [241] | ||
Chrysin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Chrysin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Chrysin through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [210], [232] | ||
Deschloroflavopiridol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Deschloroflavopiridol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Deschloroflavopiridol through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [199], [232] | ||
Fascaplysin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for Fascaplysin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Fascaplysin through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [232], [241] | ||
RGB-286147 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for RGB-286147. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RGB-286147 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [78], [232] | ||
CYC-103 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for CYC-103. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CYC-103 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [199], [232] | ||
PD-0183812 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cyclin-dependent kinase 6 (CDK6) is a therapeutic target for PD-0183812. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0183812 through regulating the expression of Cyclin-dependent kinase 6 (CDK6). | [230], [232] | ||
Cytochrome P450 2C8 (CYP2C8)
Almotriptan malate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Almotriptan malate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Almotriptan malate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [243] | ||
Aminophenazone [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Aminophenazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Aminophenazone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [244] | ||
Amiodarone hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Amiodarone hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Amiodarone hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [245] | ||
Amitriptyline hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Amitriptyline hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Amitriptyline hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [246] | ||
Amodiaquine [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Amodiaquine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Amodiaquine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [247] | ||
Anastrozole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Anastrozole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Anastrozole through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [248] | ||
Apalutamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Apalutamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Apalutamide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [249] | ||
Apixaban [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Apixaban. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Apixaban through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [250] | ||
Atorvastatin calcium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Atorvastatin calcium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Atorvastatin calcium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Azelastine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Azelastine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Azelastine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [252] | ||
Benzyl alcohol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Benzyl alcohol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Benzyl alcohol through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [253] | ||
Beraprost [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Beraprost. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Beraprost through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [254] | ||
Brigatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Brigatinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Brigatinib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [255] | ||
Bromfenac [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Bromfenac. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bromfenac through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [256] | ||
Buprenorphine hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Buprenorphine hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Buprenorphine hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [257] | ||
Cabazitaxel [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Cabazitaxel. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cabazitaxel through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [258] | ||
Caffeine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Caffeine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Caffeine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [259] | ||
Capsaicin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Capsaicin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Capsaicin through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [260] | ||
Carbamazepine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Carbamazepine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Carbamazepine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [261] | ||
Cefaloridine [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Cefaloridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cefaloridine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [262] | ||
Celecoxib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Celecoxib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Celecoxib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [263] | ||
Cerivastatin sodium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Cerivastatin sodium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cerivastatin sodium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Cisapride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Cisapride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cisapride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [264] | ||
Clozapine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Clozapine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Clozapine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [265] | ||
Cyclophosphamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Cyclophosphamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyclophosphamide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [266] | ||
Dabrafenib mesylate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Dabrafenib mesylate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dabrafenib mesylate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Dapsone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Dapsone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dapsone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [267] | ||
Desloratadine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Desloratadine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Desloratadine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [268] | ||
Dexibuprofen [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Dexibuprofen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dexibuprofen through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [269] | ||
Diazepam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Diazepam. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Diazepam through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [270] | ||
Diclofenac sodium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Diclofenac sodium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Diclofenac sodium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [271] | ||
Diethylstilbestrol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Diethylstilbestrol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Diethylstilbestrol through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [272] | ||
Diltiazem hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Diltiazem hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Diltiazem hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [273] | ||
Eltrombopag olamine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Eltrombopag olamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Eltrombopag olamine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [274] | ||
Enasidenib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Enasidenib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Enasidenib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [275] | ||
Enzalutamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Enzalutamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Enzalutamide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Estradiol acetate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Estradiol acetate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Estradiol acetate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Estradiol cypionate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Estradiol cypionate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Estradiol cypionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [276] | ||
Estradiol valerate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Estradiol valerate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Estradiol valerate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [276] | ||
Eszopiclone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Eszopiclone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Eszopiclone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [277] | ||
Ethinyl estradiol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ethinyl estradiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ethinyl estradiol through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [278] | ||
Fluvastatin sodium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Fluvastatin sodium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Fluvastatin sodium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [279] | ||
Glasdegib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Glasdegib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Glasdegib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [280] | ||
Halofantrine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Halofantrine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Halofantrine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [281] | ||
Ibuprofen [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ibuprofen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ibuprofen through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [269] | ||
Ifosfamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ifosfamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ifosfamide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [266] | ||
Imatinib mesylate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Imatinib mesylate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Imatinib mesylate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Irbesartan [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Irbesartan. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Irbesartan through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [278] | ||
Istradefylline [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Istradefylline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Istradefylline through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [282] | ||
Ixazomib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ixazomib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ixazomib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [283] | ||
Ketobemidone [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ketobemidone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ketobemidone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [284] | ||
Ketorolac [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ketorolac. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ketorolac through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [285] | ||
Lansoprazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Lansoprazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lansoprazole through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [286] | ||
Lapatinib ditosylate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Lapatinib ditosylate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lapatinib ditosylate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [287] | ||
Levomilnacipran [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Levomilnacipran. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Levomilnacipran through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [288] | ||
Lidocaine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Lidocaine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lidocaine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [289] | ||
Loperamide hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Loperamide hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Loperamide hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [290] | ||
Loratadine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Loratadine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Loratadine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Lorlatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Lorlatinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lorlatinib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [291] | ||
Losartan potassium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Losartan potassium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Losartan potassium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [292] | ||
Lovastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Lovastatin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lovastatin through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [293] | ||
Mefenamic acid [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Mefenamic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Mefenamic acid through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Meloxicam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Meloxicam. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Meloxicam through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [294] | ||
Mephenytoin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Mephenytoin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Mephenytoin through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [295] | ||
Mestranol [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Mestranol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Mestranol through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [296] | ||
Methadone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Methadone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Methadone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [297] | ||
Mirtazapine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Mirtazapine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Mirtazapine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [289] | ||
Montelukast sodium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Montelukast sodium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Montelukast sodium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [298] | ||
Morphine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Morphine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Morphine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [299] | ||
Mycophenolate mofetil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Mycophenolate mofetil. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Mycophenolate mofetil through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [300] | ||
Naloxone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Naloxone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Naloxone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [257] | ||
Naproxen [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Naproxen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Naproxen through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [301] | ||
Nicardipine hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Nicardipine hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nicardipine hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [289] | ||
Nicotine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Nicotine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nicotine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [302] | ||
Nilotinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Nilotinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nilotinib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Ombitasvir [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Ombitasvir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ombitasvir through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [303] | ||
Omeprazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Omeprazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Omeprazole through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [304] | ||
Pazopanib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Pazopanib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pazopanib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [305] | ||
Pentamidine isethionate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Pentamidine isethionate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pentamidine isethionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [306] | ||
Perphenazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Perphenazine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Perphenazine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [307] | ||
Phenobarbital [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Phenobarbital. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Phenobarbital through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [308] | ||
Phenprocoumon [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Phenprocoumon. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Phenprocoumon through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [309] | ||
Phenytoin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Phenytoin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Phenytoin through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [289] | ||
Pioglitazone hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Pioglitazone hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pioglitazone hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [310] | ||
Piroxicam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Piroxicam. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Piroxicam through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [311] | ||
Pitavastatin calcium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Pitavastatin calcium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pitavastatin calcium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [312] | ||
Propofol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Propofol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Propofol through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [313] | ||
Quinidine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Quinidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Quinidine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Quinine sulfate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Quinine sulfate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Quinine sulfate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Repaglinide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Repaglinide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Repaglinide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [314] | ||
Riociguat [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Riociguat. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Riociguat through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [315] | ||
Rofecoxib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Rofecoxib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rofecoxib through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Rosiglitazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Rosiglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rosiglitazone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [316] | ||
Selegiline hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Selegiline hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Selegiline hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [317] | ||
Selexipag [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Selexipag. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Selexipag through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [318] | ||
Simvastatin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Simvastatin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Simvastatin through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [319] | ||
Sitagliptin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Sitagliptin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sitagliptin through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [320] | ||
Sulfadiazine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Sulfadiazine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sulfadiazine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [321] | ||
Sulfamethoxazole [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Sulfamethoxazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sulfamethoxazole through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [322] | ||
Sulfinpyrazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Sulfinpyrazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sulfinpyrazone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [289] | ||
Tazarotene [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Tazarotene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tazarotene through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [323] | ||
Tegafur [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Tegafur. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tegafur through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [324] | ||
Temazepam [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Temazepam. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Temazepam through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [325] | ||
Terbinafine hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Terbinafine hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Terbinafine hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [277] | ||
Testosterone cypionate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone cypionate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Testosterone enanthate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone enanthate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testosterone enanthate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Testosterone undecanoate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone undecanoate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testosterone undecanoate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
Thalidomide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Thalidomide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Thalidomide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [326] | ||
Tolbutamide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Tolbutamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tolbutamide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [327] | ||
Torasemide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Torasemide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Torasemide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [328] | ||
Treprostinil [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Treprostinil. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Treprostinil through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [329] | ||
Trifarotene [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Trifarotene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Trifarotene through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [330] | ||
Trimethadione [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Trimethadione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Trimethadione through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [331] | ||
Trimethoprim [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Trimethoprim. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Trimethoprim through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [332] | ||
Troglitazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Troglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Troglitazone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [333] | ||
Velpatasvir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Velpatasvir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Velpatasvir through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [334] | ||
Verapamil hydrochloride [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Verapamil hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Verapamil hydrochloride through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [335] | ||
Vortioxetine hydrobromide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Vortioxetine hydrobromide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Vortioxetine hydrobromide through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [336] | ||
Voxilaprevir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Voxilaprevir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Voxilaprevir through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [334] | ||
Warfarin sodium [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Warfarin sodium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Warfarin sodium through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [301] | ||
Zafirlukast [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Zafirlukast. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Zafirlukast through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [332] | ||
Zidovudine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Zidovudine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Zidovudine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [289] | ||
Zopiclone [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Zopiclone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Zopiclone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [337] | ||
BMS-298585 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for BMS-298585. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-298585 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [338] | ||
BNP-1350 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for BNP-1350. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BNP-1350 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [339] | ||
CKD-501 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for CKD-501. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CKD-501 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [340] | ||
CYT-387 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for CYT-387. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CYT-387 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [341] | ||
Dasabuvir [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Dasabuvir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dasabuvir through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [342] | ||
Domperidone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Domperidone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Domperidone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [343] | ||
DRF-2593 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for DRF-2593. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DRF-2593 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [340] | ||
EMD-128130 [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for EMD-128130. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of EMD-128130 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [344] | ||
Estradiol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Estradiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Estradiol through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [251] | ||
LAS-17177 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for LAS-17177. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LAS-17177 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [345] | ||
LAU-7b [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for LAU-7b. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LAU-7b through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [346] | ||
LY-2484595 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for LY-2484595. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY-2484595 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [347] | ||
NSC-122758 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for NSC-122758. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-122758 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [348] | ||
QLT-091001 [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for QLT-091001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of QLT-091001 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [348] | ||
Rivoglitazone [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Rivoglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rivoglitazone through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [349] | ||
AZD-2014 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for AZD-2014. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD-2014 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [350] | ||
GSK-1278863 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for GSK-1278863. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-1278863 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [351] | ||
TAK-652 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for TAK-652. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAK-652 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [352] | ||
AG-1549 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for AG-1549. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AG-1549 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [353] | ||
AZD-9496 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for AZD-9496. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD-9496 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [354] | ||
H3B-6545 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for H3B-6545. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of H3B-6545 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [355] | ||
M-813 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for M-813. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of M-813 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [356] | ||
MK-0822 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for MK-0822. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-0822 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [357] | ||
Antipyrine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Antipyrine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Antipyrine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [277] | ||
Cyamemazine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Cyamemazine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cyamemazine through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [358] | ||
Paraoxon [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Paraoxon. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Paraoxon through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [359] | ||
ABT-001 [Discontinued]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for ABT-001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABT-001 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [360] | ||
ADD-3878 [Discontinued]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for ADD-3878. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ADD-3878 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [340] | ||
Aleglitazar [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Aleglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Aleglitazar through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [361] | ||
ML-3000 [Discontinued]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for ML-3000. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ML-3000 through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [242], [277] | ||
Dehydrogenase/reductase retSDR2 (HSD17B11)
Hombreol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Dehydrogenase/reductase retSDR2 (HSD17B11) is a therapeutic target for Hombreol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Hombreol through regulating the expression of Dehydrogenase/reductase retSDR2 (HSD17B11). | [362], [363] | ||
Diacylglycerol O-acyltransferase 2 (DGAT2)
Vitamin B3 [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Diacylglycerol O-acyltransferase 2 (DGAT2) is a therapeutic target for Vitamin B3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Vitamin B3 through regulating the expression of Diacylglycerol O-acyltransferase 2 (DGAT2). | [364], [365] | ||
ARI-3037MO [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Diacylglycerol O-acyltransferase 2 (DGAT2) is a therapeutic target for ARI-3037MO. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ARI-3037MO through regulating the expression of Diacylglycerol O-acyltransferase 2 (DGAT2). | [364], [366] | ||
ION 224 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Diacylglycerol O-acyltransferase 2 (DGAT2) is a therapeutic target for ION 224. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ION 224 through regulating the expression of Diacylglycerol O-acyltransferase 2 (DGAT2). | [364], [367] | ||
PF-06427878 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Diacylglycerol O-acyltransferase 2 (DGAT2) is a therapeutic target for PF-06427878. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-06427878 through regulating the expression of Diacylglycerol O-acyltransferase 2 (DGAT2). | [364], [368] | ||
Dickkopf-related protein 1 (DKK1)
BHQ880 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Dickkopf-related protein 1 (DKK1) is a therapeutic target for BHQ880. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BHQ880 through regulating the expression of Dickkopf-related protein 1 (DKK1). | [369], [370] | ||
DKN-01 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Dickkopf-related protein 1 (DKK1) is a therapeutic target for DKN-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DKN-01 through regulating the expression of Dickkopf-related protein 1 (DKK1). | [369], [371] | ||
PF-04840082 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Dickkopf-related protein 1 (DKK1) is a therapeutic target for PF-04840082. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-04840082 through regulating the expression of Dickkopf-related protein 1 (DKK1). | [369], [372] | ||
E2F transcription factor 1 (E2F1)
ARQ-171 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | E2F transcription factor 1 (E2F1) is a therapeutic target for ARQ-171. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ARQ-171 through regulating the expression of E2F transcription factor 1 (E2F1). | [373], [374] | ||
ISIS 113019 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | E2F transcription factor 1 (E2F1) is a therapeutic target for ISIS 113019. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113019 through regulating the expression of E2F transcription factor 1 (E2F1). | [373], [375] | ||
ISIS 113020 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | E2F transcription factor 1 (E2F1) is a therapeutic target for ISIS 113020. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113020 through regulating the expression of E2F transcription factor 1 (E2F1). | [373], [375] | ||
ISIS 113021 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | E2F transcription factor 1 (E2F1) is a therapeutic target for ISIS 113021. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113021 through regulating the expression of E2F transcription factor 1 (E2F1). | [373], [375] | ||
ISIS 113022 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | E2F transcription factor 1 (E2F1) is a therapeutic target for ISIS 113022. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113022 through regulating the expression of E2F transcription factor 1 (E2F1). | [373], [375] | ||
ISIS 113048 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | E2F transcription factor 1 (E2F1) is a therapeutic target for ISIS 113048. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113048 through regulating the expression of E2F transcription factor 1 (E2F1). | [373], [376] | ||
Endostatin (COL18A1)
RetinoStat [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Endostatin (COL18A1) is a therapeutic target for RetinoStat. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RetinoStat through regulating the expression of Endostatin (COL18A1). | [149], [377] | ||
Endo-CD [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Endostatin (COL18A1) is a therapeutic target for Endo-CD. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Endo-CD through regulating the expression of Endostatin (COL18A1). | [149], [378] | ||
Ephrin type-B receptor 2 (EPHB2)
BVD-523 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-B receptor 2 (EPHB2) is a therapeutic target for BVD-523. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BVD-523 through regulating the expression of Ephrin type-B receptor 2 (EPHB2). | [379], [380] | ||
SEphB4-HSA [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-B receptor 2 (EPHB2) is a therapeutic target for SEphB4-HSA. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SEphB4-HSA through regulating the expression of Ephrin type-B receptor 2 (EPHB2). | [379], [381] | ||
KO-947 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-B receptor 2 (EPHB2) is a therapeutic target for KO-947. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KO-947 through regulating the expression of Ephrin type-B receptor 2 (EPHB2). | [38], [379] | ||
MK-8353 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-B receptor 2 (EPHB2) is a therapeutic target for MK-8353. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-8353 through regulating the expression of Ephrin type-B receptor 2 (EPHB2). | [38], [379] | ||
AMP-PNP [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-B receptor 2 (EPHB2) is a therapeutic target for AMP-PNP. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMP-PNP through regulating the expression of Ephrin type-B receptor 2 (EPHB2). | [379], [382] | ||
SNEWIQPRLPQH [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ephrin type-B receptor 2 (EPHB2) is a therapeutic target for SNEWIQPRLPQH. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SNEWIQPRLPQH through regulating the expression of Ephrin type-B receptor 2 (EPHB2). | [38], [379] | ||
Erbb2 tyrosine kinase receptor (HER2)
Afatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Afatinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Afatinib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [384] | ||
Dacomitinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Dacomitinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dacomitinib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [233], [383] | ||
Lapatinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Lapatinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lapatinib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [31], [383] | ||
Margetuximab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Margetuximab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Margetuximab through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [385] | ||
Masoprocol [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Masoprocol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Masoprocol through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [386] | ||
Merimepodib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Merimepodib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Merimepodib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [387] | ||
NERATINIB MALEATE [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for NERATINIB MALEATE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NERATINIB MALEATE through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [388] | ||
Pertuzumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Pertuzumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pertuzumab through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [389] | ||
Trastuzumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Trastuzumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Trastuzumab through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [390] | ||
HKI-272 [Phase 3]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HKI-272. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HKI-272 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [38], [383] | ||
Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HKI-272. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HKI-272 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [391] | |||
Nelipepimut S [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Nelipepimut S. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nelipepimut S through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [392] | ||
NeuVax [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for NeuVax. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NeuVax through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [201], [383] | ||
PF-05280014 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for PF-05280014. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-05280014 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [29], [383] | ||
Trastuzumab-DM1 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Trastuzumab-DM1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Trastuzumab-DM1 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [393] | ||
Varlitinib [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Varlitinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Varlitinib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [31], [383] | ||
A166 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for A166. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of A166 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [394] | ||
ABY-025 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ABY-025. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABY-025 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [395] | ||
AGN-208397 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for AGN-208397. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AGN-208397 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [396] | ||
Anti-HER2 CAR-T [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Anti-HER2 CAR-T. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Anti-HER2 CAR-T through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [397] | ||
AU105 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for AU105. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AU105 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [38], [383] | ||
AVX901 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for AVX901. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AVX901 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [398] | ||
AZD8931 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for AZD8931. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD8931 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [390] | ||
BDTX-189 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for BDTX-189. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BDTX-189 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [399] | ||
BMS-599626 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for BMS-599626. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-599626 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [201], [383] | ||
BMS-690514 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for BMS-690514. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-690514 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [400] | ||
CART-HER-2 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CART-HER-2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CART-HER-2 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [401] | ||
CI-1033 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CI-1033. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CI-1033 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [38], [383] | ||
CP-724714 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CP-724714. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CP-724714 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [402] | ||
DN24-02 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for DN24-02. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DN24-02 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [403] | ||
Ertumaxomab [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Ertumaxomab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ertumaxomab through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [201], [383] | ||
HER-2 Protein AutoVac [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HER-2 Protein AutoVac. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HER-2 Protein AutoVac through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [404] | ||
HER-2-targeting CAR T Cells [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HER-2-targeting CAR T Cells. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HER-2-targeting CAR T Cells through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [118], [383] | ||
Her2-targeted autologous T-cell therapy [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Her2-targeted autologous T-cell therapy. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Her2-targeted autologous T-cell therapy through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [405] | ||
HM-78136B [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HM-78136B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HM-78136B through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [406] | ||
ISB 1302 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISB 1302. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISB 1302 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [407] | ||
KN026 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for KN026. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KN026 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [408] | ||
MCLA-128 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MCLA-128. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MCLA-128 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [409] | ||
MGAH22 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MGAH22. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MGAH22 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [410] | ||
MM-111 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MM-111. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MM-111 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [411] | ||
MRG002 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MRG002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MRG002 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [412] | ||
Sym013 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Sym013. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sym013 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [413] | ||
Tarloxotinib [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Tarloxotinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tarloxotinib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [166], [383] | ||
TAS-0728 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for TAS-0728. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAS-0728 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [414] | ||
Zenocutuzomab [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Zenocutuzomab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Zenocutuzomab through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [415] | ||
AIP-303 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for AIP-303. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AIP-303 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [416] | ||
ARRY-380 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ARRY-380. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ARRY-380 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [166], [383] | ||
BAY 2701439 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for BAY 2701439. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BAY 2701439 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [417] | ||
CAR-T Cells targeting HER2 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CAR-T Cells targeting HER2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CAR-T Cells targeting HER2 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [418] | ||
CAR-T cells targeting HER2 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CAR-T cells targeting HER2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CAR-T cells targeting HER2 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [419] | ||
Cipatinib [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Cipatinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cipatinib through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [420] | ||
CUDC-101 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CUDC-101. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CUDC-101 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [421] | ||
DZD1516 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for DZD1516. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DZD1516 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [422] | ||
GBR1302 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for GBR1302. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GBR1302 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [423] | ||
GQ1001 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for GQ1001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GQ1001 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [424] | ||
HER2-CAR T Cells [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HER2-CAR T Cells. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HER2-CAR T Cells through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [38], [383] | ||
HER2-specific CAR T cell [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HER2-specific CAR T cell. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HER2-specific CAR T cell through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [425] | ||
HER2-specific T cells [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HER2-specific T cells. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HER2-specific T cells through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [426] | ||
HER2p63-71 peptide vaccine [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HER2p63-71 peptide vaccine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HER2p63-71 peptide vaccine through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [427] | ||
JNJ-26483327 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for JNJ-26483327. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of JNJ-26483327 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [428] | ||
M802 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for M802. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of M802 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [429] | ||
MB-103 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MB-103. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MB-103 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [430] | ||
MBS301 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MBS301. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MBS301 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [431] | ||
MEDI4276 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MEDI4276. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MEDI4276 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [432] | ||
MM-302 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MM-302. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MM-302 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [433] | ||
MT-5111 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MT-5111. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MT-5111 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [434] | ||
MVA HER-2 AutoVac [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for MVA HER-2 AutoVac. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MVA HER-2 AutoVac through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [435] | ||
NJH395 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for NJH395. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NJH395 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [436] | ||
Recombinant human Erbb3 fragment therapeutic tumor vaccine [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Recombinant human Erbb3 fragment therapeutic tumor vaccine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Recombinant human Erbb3 fragment therapeutic tumor vaccine through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [437] | ||
S-222611 [Phase 1b]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for S-222611. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of S-222611 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [438] | ||
SBT6050 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for SBT6050. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SBT6050 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [439] | ||
TAK-285 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for TAK-285. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAK-285 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [440] | ||
TrasGEX [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for TrasGEX. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TrasGEX through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [441] | ||
VM-206 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for VM-206. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VM-206 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [442] | ||
Zemab [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Zemab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Zemab through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [443] | ||
ZW49 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ZW49. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZW49 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [444] | ||
227Th-labelled HER2-TTC [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 227Th-labelled HER2-TTC. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 227Th-labelled HER2-TTC through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [201], [383] | ||
(1-Benzyl-1H-indazol-5-yl)-quinazolin-4-yl-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for (1-Benzyl-1H-indazol-5-yl)-quinazolin-4-yl-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (1-Benzyl-1H-indazol-5-yl)-quinazolin-4-yl-amine through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [445] | ||
(1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine [Investigative]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for (1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [446] | ||
Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for (1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [447] | |||
3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [210], [383] | ||
3,4-diphenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 3,4-diphenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-diphenyl-1H-pyrrole-2,5-dione through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [448] | ||
3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [449] | ||
3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [210], [383] | ||
4-(3-phenoxylphenyl)-5-cyano-2H-1,2,3-triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 4-(3-phenoxylphenyl)-5-cyano-2H-1,2,3-triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3-phenoxylphenyl)-5-cyano-2H-1,2,3-triazole through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [447] | ||
4-(4-bromophenyl)-5-cyano-2H-1,2,3-triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 4-(4-bromophenyl)-5-cyano-2H-1,2,3-triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(4-bromophenyl)-5-cyano-2H-1,2,3-triazole through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [447] | ||
4-(4-chlorophenyl)-5-cyano-2H-1,2,3-triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 4-(4-chlorophenyl)-5-cyano-2H-1,2,3-triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(4-chlorophenyl)-5-cyano-2H-1,2,3-triazole through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [447] | ||
4-(4-isopropylphenyl)-5-cyano-2H-1,2,3-triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 4-(4-isopropylphenyl)-5-cyano-2H-1,2,3-triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(4-isopropylphenyl)-5-cyano-2H-1,2,3-triazole through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [210], [383] | ||
4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [450] | ||
4557W [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for 4557W. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4557W through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [449] | ||
AG-213 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for AG-213. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AG-213 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [451] | ||
BMS 536924 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for BMS 536924. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS 536924 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [452] | ||
CL-387785 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for CL-387785. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CL-387785 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [210], [383] | ||
Geldanamycin-estradiol hybrid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Geldanamycin-estradiol hybrid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Geldanamycin-estradiol hybrid through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [453] | ||
HDS-029 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for HDS-029. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HDS-029 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [454] | ||
ISIS 12882 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISIS 12882. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 12882 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [455] | ||
ISIS 12883 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISIS 12883. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 12883 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [455] | ||
ISIS 12884 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISIS 12884. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 12884 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [226], [383] | ||
ISIS 9002 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISIS 9002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 9002 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [455] | ||
ISIS 9003 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISIS 9003. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 9003 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [455] | ||
ISIS 9005 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for ISIS 9005. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 9005 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [455] | ||
N-(4-m-Tolylamino-quinazolin-6-yl)-acrylamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for N-(4-m-Tolylamino-quinazolin-6-yl)-acrylamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(4-m-Tolylamino-quinazolin-6-yl)-acrylamide through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [446] | ||
PD-168393 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for PD-168393. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-168393 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [453] | ||
PF 5208766 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for PF 5208766. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF 5208766 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [456] | ||
PNT-500 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for PNT-500. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PNT-500 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [446] | ||
Redoxal [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Redoxal. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Redoxal through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [446] | ||
TA1-RTA [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for TA1-RTA. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TA1-RTA through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [457] | ||
GW-974 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for GW-974. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-974 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [458] | ||
Her-2-Bi-armed ATC [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for Her-2-Bi-armed ATC. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Her-2-Bi-armed ATC through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [459] | ||
TAK165 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Erbb2 tyrosine kinase receptor (HER2) is a therapeutic target for TAK165. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAK165 through regulating the expression of Erbb2 tyrosine kinase receptor (HER2). | [383], [460] | ||
Fatty acid synthase (FASN)
Cerulenin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for Cerulenin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cerulenin through regulating the expression of Fatty acid synthase (FASN). | [461], [462] | ||
TVB-2640 [Phase 2]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for TVB-2640. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TVB-2640 through regulating the expression of Fatty acid synthase (FASN). | [461], [463] | ||
Fatty acid synthase (FASN) is a therapeutic target for TVB-2640. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TVB-2640 through regulating the expression of Fatty acid synthase (FASN). | [461], [464] | |||
FAS1 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for FAS1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FAS1 through regulating the expression of Fatty acid synthase (FASN). | [461], [462] | ||
FSA2 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for FSA2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FSA2 through regulating the expression of Fatty acid synthase (FASN). | [461], [465] | ||
(-)-CATECHINGALLATE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for (-)-CATECHINGALLATE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (-)-CATECHINGALLATE through regulating the expression of Fatty acid synthase (FASN). | [461], [466] | ||
2-Hexadecynoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for 2-Hexadecynoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Hexadecynoic acid through regulating the expression of Fatty acid synthase (FASN). | [461], [462] | ||
3,7,3',4'-TETRAHYDROXYFLAVONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for 3,7,3',4'-TETRAHYDROXYFLAVONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,7,3',4'-TETRAHYDROXYFLAVONE through regulating the expression of Fatty acid synthase (FASN). | [461], [464] | ||
4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for 4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-hydroxy-6-nitro-3-phenylquinolin-2(1H)-one through regulating the expression of Fatty acid synthase (FASN). | [461], [464] | ||
4-hydroxy-8-nitro-3-phenylquinolin-2(1H)-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for 4-hydroxy-8-nitro-3-phenylquinolin-2(1H)-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-hydroxy-8-nitro-3-phenylquinolin-2(1H)-one through regulating the expression of Fatty acid synthase (FASN). | [461], [467] | ||
Anti-Fas mabs [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for Anti-Fas mabs. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Anti-Fas mabs through regulating the expression of Fatty acid synthase (FASN). | [461], [468] | ||
biochanin A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for biochanin A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of biochanin A through regulating the expression of Fatty acid synthase (FASN). | [461], [464] | ||
C75 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for C75. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C75 through regulating the expression of Fatty acid synthase (FASN). | [461], [464] | ||
FAS-031 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for FAS-031. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FAS-031 through regulating the expression of Fatty acid synthase (FASN). | [461], [468] | ||
GALLOCATECHIN GALLATE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for GALLOCATECHIN GALLATE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GALLOCATECHIN GALLATE through regulating the expression of Fatty acid synthase (FASN). | [461], [466] | ||
GSK2194069 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for GSK2194069. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK2194069 through regulating the expression of Fatty acid synthase (FASN). | [461], [469] | ||
MG-28 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for MG-28. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MG-28 through regulating the expression of Fatty acid synthase (FASN). | [461], [470] | ||
MORIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for MORIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MORIN through regulating the expression of Fatty acid synthase (FASN). | [461], [464] | ||
MT-061 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Fatty acid synthase (FASN) is a therapeutic target for MT-061. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MT-061 through regulating the expression of Fatty acid synthase (FASN). | [461], [468] | ||
Follicle-stimulating hormone receptor (FSHR)
Follitropin beta [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for Follitropin beta. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Follitropin beta through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [471] | ||
Menotropins [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for Menotropins. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Menotropins through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [472] | ||
Urofollitropin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for Urofollitropin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Urofollitropin through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [473] | ||
Suramin [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for Suramin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Suramin through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [474] | ||
FSHR NAM [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for FSHR NAM. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FSHR NAM through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [475] | ||
Long-acting FSH conjugate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for Long-acting FSH conjugate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Long-acting FSH conjugate through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [474] | ||
PRX-111 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for PRX-111. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PRX-111 through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [474] | ||
Recombinant follicle stimulating hormone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Follicle-stimulating hormone receptor (FSHR) is a therapeutic target for Recombinant follicle stimulating hormone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Recombinant follicle stimulating hormone through regulating the expression of Follicle-stimulating hormone receptor (FSHR). | [53], [476] | ||
Forkhead box protein O1A (FOXO1)
AS-1708727 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for AS-1708727. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AS-1708727 through regulating the expression of Forkhead box protein O1A (FOXO1). | [364], [477] | ||
ISIS 188755 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188755. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188755 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188757 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188757. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188757 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188759 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188759. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188759 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188761 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188761. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188761 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188763 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188763. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188763 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188778 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188778. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188778 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188780 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188780. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188780 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188781 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188781. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188781 through regulating the expression of Forkhead box protein O1A (FOXO1). | [143], [364] | ||
ISIS 188782 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Forkhead box protein O1A (FOXO1) is a therapeutic target for ISIS 188782. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 188782 through regulating the expression of Forkhead box protein O1A (FOXO1). | [226], [364] | ||
Frizzled-10 (FZD10)
OTSA-101-DTPA-90Y [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Frizzled-10 (FZD10) is a therapeutic target for OTSA-101-DTPA-90Y. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OTSA-101-DTPA-90Y through regulating the expression of Frizzled-10 (FZD10). | [166], [478] | ||
G1/S-specific cyclin-D1 (CCND1)
ABT-263 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for ABT-263. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABT-263 through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [479], [480] | ||
Briciclib [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for Briciclib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Briciclib through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [38], [479] | ||
3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-di-(4-methoxyphenyl)-1H-pyrrole-2,5-dione through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [210], [479] | ||
3,4-diphenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for 3,4-diphenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-diphenyl-1H-pyrrole-2,5-dione through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [210], [479] | ||
3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-methoxyphenyl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [479], [481] | ||
3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for 3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(indole-3-yl)-4-phenyl-1H-pyrrole-2,5-dione through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [210], [479] | ||
7-hydroxycoumarin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | G1/S-specific cyclin-D1 (CCND1) is a therapeutic target for 7-hydroxycoumarin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-hydroxycoumarin through regulating the expression of G1/S-specific cyclin-D1 (CCND1). | [195], [479] | ||
Ghrelin (GHRL)
Unacylated ghrelin [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Ghrelin (GHRL) is a therapeutic target for Unacylated ghrelin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Unacylated ghrelin through regulating the expression of Ghrelin (GHRL). | [482], [483] | ||
Glutamate receptor ionotropic NMDA 1 (NMDAR1)
Cycloserine [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Cycloserine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cycloserine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [485] | ||
D-serine [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for D-serine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of D-serine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [486] | ||
ELIPRODIL [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for ELIPRODIL. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ELIPRODIL through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [148], [484] | ||
NBQX [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for NBQX. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NBQX through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [487] | ||
(D)-Ala-Pro-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for (D)-Ala-Pro-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (D)-Ala-Pro-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
(R)-2-Amino-5-phosphono-pentanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for (R)-2-Amino-5-phosphono-pentanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (R)-2-Amino-5-phosphono-pentanoic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
(R)-2-Amino-7-phosphono-heptanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for (R)-2-Amino-7-phosphono-heptanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (R)-2-Amino-7-phosphono-heptanoic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
(RS)-(tetrazol-5-yl)glycine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for (RS)-(tetrazol-5-yl)glycine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (RS)-(tetrazol-5-yl)glycine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [78], [484] | ||
1,3-ditolylguanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 1,3-ditolylguanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1,3-ditolylguanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [491] | ||
2-(4-Phenoxy-benzyl)-1H-benzoimidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 2-(4-Phenoxy-benzyl)-1H-benzoimidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(4-Phenoxy-benzyl)-1H-benzoimidazole through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [492] | ||
2-(4-Phenoxy-benzyl)-3H-benzoimidazol-4-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 2-(4-Phenoxy-benzyl)-3H-benzoimidazol-4-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(4-Phenoxy-benzyl)-3H-benzoimidazol-4-ol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [492] | ||
2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [492] | ||
2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ylamine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [492] | ||
2-Methylamino-succinic acid(NMDA) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 2-Methylamino-succinic acid(NMDA). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Methylamino-succinic acid(NMDA) through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [493] | ||
2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [494] | ||
3-Carbamoyl-6-chloro-1H-indole-2-carboxylic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 3-Carbamoyl-6-chloro-1H-indole-2-carboxylic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Carbamoyl-6-chloro-1H-indole-2-carboxylic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
3-Hydroxy-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 3-Hydroxy-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Hydroxy-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
3-Hydroxy-6-methyl-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 3-Hydroxy-6-methyl-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Hydroxy-6-methyl-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
3-Hydroxy-7-nitro-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 3-Hydroxy-7-nitro-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Hydroxy-7-nitro-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
3-Hydroxy-8-methyl-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 3-Hydroxy-8-methyl-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Hydroxy-8-methyl-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [496] | ||
3-phenyl-4-hydroxyquinolin-2(1H)-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 3-phenyl-4-hydroxyquinolin-2(1H)-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-phenyl-4-hydroxyquinolin-2(1H)-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [494] | ||
4,5,7-Trichloro-3-hydroxy-1H-quinolin-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4,5,7-Trichloro-3-hydroxy-1H-quinolin-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4,5,7-Trichloro-3-hydroxy-1H-quinolin-2-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [497] | ||
4,6-Dichloro-1H-indole-2-carboxylic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4,6-Dichloro-1H-indole-2-carboxylic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4,6-Dichloro-1H-indole-2-carboxylic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [498] | ||
4-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinoline through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
4-Benzyl-1-(2-phenoxy-ethyl)-piperidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-Benzyl-1-(2-phenoxy-ethyl)-piperidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Benzyl-1-(2-phenoxy-ethyl)-piperidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [499] | ||
4-Benzyl-1-phenethyl-piperidine hydrochloride [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-Benzyl-1-phenethyl-piperidine hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Benzyl-1-phenethyl-piperidine hydrochloride through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
4-Bromo-3-hydroxy-1H-quinolin-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-Bromo-3-hydroxy-1H-quinolin-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Bromo-3-hydroxy-1H-quinolin-2-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [497] | ||
4-Bromo-5,7-dichloro-3-hydroxy-1H-quinolin-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-Bromo-5,7-dichloro-3-hydroxy-1H-quinolin-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Bromo-5,7-dichloro-3-hydroxy-1H-quinolin-2-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [497] | ||
4-Chloro-3-hydroxy-1H-quinolin-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-Chloro-3-hydroxy-1H-quinolin-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Chloro-3-hydroxy-1H-quinolin-2-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [500] | ||
4-hydroxy-5-phenylthieno[2,3-b]pyridin-6(7H)-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-hydroxy-5-phenylthieno[2,3-b]pyridin-6(7H)-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-hydroxy-5-phenylthieno[2,3-b]pyridin-6(7H)-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
4-[2-(3-Phenyl-propylamino)-ethyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(3-Phenyl-propylamino)-ethyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(3-Phenyl-propylamino)-ethyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [501] | ||
4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [502] | ||
4-[2-(4-Phenyl-butoxy)-ethyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(4-Phenyl-butoxy)-ethyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(4-Phenyl-butoxy)-ethyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
4-[2-(4-Phenyl-butylamino)-ethyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(4-Phenyl-butylamino)-ethyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(4-Phenyl-butylamino)-ethyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
4-[2-(4-Phenyl-piperidin-1-yl)-ethoxy]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(4-Phenyl-piperidin-1-yl)-ethoxy]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(4-Phenyl-piperidin-1-yl)-ethoxy]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [503] | ||
4-[2-(5-Phenyl-pentylamino)-ethyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(5-Phenyl-pentylamino)-ethyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(5-Phenyl-pentylamino)-ethyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
4-[2-(6-Phenyl-hexylamino)-ethyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[2-(6-Phenyl-hexylamino)-ethyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[2-(6-Phenyl-hexylamino)-ethyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
4-[3-(4-Phenyl-butylamino)-propyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[3-(4-Phenyl-butylamino)-propyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[3-(4-Phenyl-butylamino)-propyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [504] | ||
4-[3-(5-Phenyl-pentylamino)-propyl]-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-[3-(5-Phenyl-pentylamino)-propyl]-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-[3-(5-Phenyl-pentylamino)-propyl]-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [487] | ||
4-{2-[Ethyl-(4-phenyl-butyl)-amino]-ethyl}-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 4-{2-[Ethyl-(4-phenyl-butyl)-amino]-ethyl}-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-{2-[Ethyl-(4-phenyl-butyl)-amino]-ethyl}-phenol through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
5,6,7-Trichloro-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,6,7-Trichloro-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,6,7-Trichloro-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [505] | ||
5,7-Dibromo-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,7-Dibromo-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dibromo-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [505] | ||
5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [505] | ||
5,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [505] | ||
5,7-Dichloro-4-hydroxy-3-phenyl-1H-quinolin-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,7-Dichloro-4-hydroxy-3-phenyl-1H-quinolin-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dichloro-4-hydroxy-3-phenyl-1H-quinolin-2-one through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [501] | ||
5,7-Dichlorokynurenic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,7-Dichlorokynurenic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dichlorokynurenic Acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [506] | ||
5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [501] | ||
6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [507] | ||
6,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 6,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
6-Chloro-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 6-Chloro-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Chloro-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [509] | ||
6-Methoxy-2-(4-phenoxy-benzyl)-1H-benzoimidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 6-Methoxy-2-(4-phenoxy-benzyl)-1H-benzoimidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Methoxy-2-(4-phenoxy-benzyl)-1H-benzoimidazole through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [492] | ||
6-Nitro-1,4-dihydro-quinoxaline-2,3-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 6-Nitro-1,4-dihydro-quinoxaline-2,3-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Nitro-1,4-dihydro-quinoxaline-2,3-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
6-Nitro-2-(4-phenoxy-benzyl)-1H-benzoimidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 6-Nitro-2-(4-phenoxy-benzyl)-1H-benzoimidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Nitro-2-(4-phenoxy-benzyl)-1H-benzoimidazole through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
7-chloro-3-hydroxyquinazoline-2,4-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 7-chloro-3-hydroxyquinazoline-2,4-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-chloro-3-hydroxyquinazoline-2,4-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [510] | ||
8-Bromo-3-hydroxy-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 8-Bromo-3-hydroxy-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-Bromo-3-hydroxy-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
8-Chloro-3-hydroxy-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 8-Chloro-3-hydroxy-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-Chloro-3-hydroxy-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
8-Ethyl-3-hydroxy-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 8-Ethyl-3-hydroxy-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-Ethyl-3-hydroxy-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
8-Fluoro-3-hydroxy-1H-benzo[b]azepine-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for 8-Fluoro-3-hydroxy-1H-benzo[b]azepine-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-Fluoro-3-hydroxy-1H-benzo[b]azepine-2,5-dione through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
Ala-Pro-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Ala-Pro-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ala-Pro-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
AP-7 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for AP-7. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AP-7 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [507] | ||
Benzyl 4-aminobutyl(3-aminopropyl)carbamate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Benzyl 4-aminobutyl(3-aminopropyl)carbamate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Benzyl 4-aminobutyl(3-aminopropyl)carbamate through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [511] | ||
CGP61594 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for CGP61594. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CGP61594 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
Cycloleucine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Cycloleucine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cycloleucine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [492] | ||
D-aspartic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for D-aspartic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of D-aspartic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
DNQX [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for DNQX. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DNQX through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [495] | ||
Gly-Amp-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Gly-Amp-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gly-Amp-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [512] | ||
Gly-b7Pro-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Gly-b7Pro-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gly-b7Pro-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
Gly-Hyp-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Gly-Hyp-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gly-Hyp-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
Gly-Pip-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Gly-Pip-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gly-Pip-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
H-Gly-D-dmP-Glu-OH [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for H-Gly-D-dmP-Glu-OH. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of H-Gly-D-dmP-Glu-OH through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [510] | ||
H-Gly-dmP-Glu-OH [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for H-Gly-dmP-Glu-OH. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of H-Gly-dmP-Glu-OH through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [513] | ||
homoquinolinic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for homoquinolinic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of homoquinolinic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
L-aspartic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-aspartic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-aspartic acid through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
N,N'-Bis-(4-butoxy-phenyl)-guanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N,N'-Bis-(4-butoxy-phenyl)-guanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N'-Bis-(4-butoxy-phenyl)-guanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
N,N'-Bis-(4-butyl-phenyl)-guanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N,N'-Bis-(4-butyl-phenyl)-guanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N'-Bis-(4-butyl-phenyl)-guanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
N,N'-Bis-(4-ethyl-phenyl)-guanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N,N'-Bis-(4-ethyl-phenyl)-guanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N'-Bis-(4-ethyl-phenyl)-guanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
N,N'-Bis-(4-hexyl-phenyl)-guanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N,N'-Bis-(4-hexyl-phenyl)-guanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N'-Bis-(4-hexyl-phenyl)-guanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
N,N'-Bis-(4-isopropyl-phenyl)-guanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N,N'-Bis-(4-isopropyl-phenyl)-guanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N'-Bis-(4-isopropyl-phenyl)-guanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [508] | ||
N,N'-Bis-(4-sec-butyl-phenyl)-guanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N,N'-Bis-(4-sec-butyl-phenyl)-guanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N'-Bis-(4-sec-butyl-phenyl)-guanidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [487] | ||
N-(2-methoxybenzyl)cinnamamidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for N-(2-methoxybenzyl)cinnamamidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(2-methoxybenzyl)cinnamamidine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [503] | ||
Nle-Pro-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Nle-Pro-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nle-Pro-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
Phe-Pro-Glu [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Phe-Pro-Glu. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Phe-Pro-Glu through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [488] | ||
PHENCYCLIDINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for PHENCYCLIDINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PHENCYCLIDINE through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [509] | ||
Phenethyl-(3-phenyl-propyl)-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Phenethyl-(3-phenyl-propyl)-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Phenethyl-(3-phenyl-propyl)-amine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [487] | ||
Phenethyl-(4-phenyl-butyl)-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for Phenethyl-(4-phenyl-butyl)-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Phenethyl-(4-phenyl-butyl)-amine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [490] | ||
RPR-118723 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for RPR-118723. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RPR-118723 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [497] | ||
TRANSTORINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for TRANSTORINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TRANSTORINE through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [513] | ||
[3H]CGP39653 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for [3H]CGP39653. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]CGP39653 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
[3H]CGS19755 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for [3H]CGS19755. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]CGS19755 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
[3H]CPP [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for [3H]CPP. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]CPP through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
[3H]dizocilpine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for [3H]dizocilpine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]dizocilpine through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
[3H]MDL105519 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for [3H]MDL105519. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]MDL105519 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [489] | ||
AM-92016 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for AM-92016. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AM-92016 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [514] | ||
DIZOCILPINE [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for DIZOCILPINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DIZOCILPINE through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [501] | ||
L-687414 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-687414. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-687414 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [501] | ||
L-689560 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-689560. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-689560 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [515] | ||
L-695902 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-695902. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-695902 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [78], [484] | ||
L-698532 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-698532. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-698532 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [503] | ||
L-698544 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-698544. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-698544 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [503] | ||
L-701324 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for L-701324. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-701324 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [516] | ||
MDL-105519 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for MDL-105519. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MDL-105519 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [501] | ||
RPR-104632 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for RPR-104632. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RPR-104632 through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [517] | ||
SPERMINE [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for SPERMINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SPERMINE through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [496] | ||
YM-90K [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glutamate receptor ionotropic NMDA 1 (NMDAR1) is a therapeutic target for YM-90K. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of YM-90K through regulating the expression of Glutamate receptor ionotropic NMDA 1 (NMDAR1). | [484], [518] | ||
Glycogen synthase kinase-3 beta (GSK-3B)
AMO-02 [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for AMO-02. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMO-02 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [520] | ||
9-ING-41 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 9-ING-41. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-ING-41 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [521] | ||
Lithium [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Lithium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lithium through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [522] | ||
LY2090314 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for LY2090314. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY2090314 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [523] | ||
Neu-120 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Neu-120. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Neu-120 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [524] | ||
Tideglusib [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Tideglusib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tideglusib through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [525] | ||
(E)-N-(6-(prop-1-enyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for (E)-N-(6-(prop-1-enyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-N-(6-(prop-1-enyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [526] | ||
12,13-DEHYDRO-8-O-ACETYLMANZAMINE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 12,13-DEHYDRO-8-O-ACETYLMANZAMINE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 12,13-DEHYDRO-8-O-ACETYLMANZAMINE A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
12,13-DEHYDROMANZAMINE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 12,13-DEHYDROMANZAMINE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 12,13-DEHYDROMANZAMINE A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
3-(6-(phenylamino)-9H-purin-8-yl)benzonitrile [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 3-(6-(phenylamino)-9H-purin-8-yl)benzonitrile. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6-(phenylamino)-9H-purin-8-yl)benzonitrile through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [528] | ||
3-phenyl-4-(phenylamino)-1H-pyrrole-2,5-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 3-phenyl-4-(phenylamino)-1H-pyrrole-2,5-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-phenyl-4-(phenylamino)-1H-pyrrole-2,5-dione through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [529] | ||
4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [530] | ||
4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [531] | ||
6-deoxymanzamine X [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 6-deoxymanzamine X. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-deoxymanzamine X through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
8-O-(4-bromobenzenesulfonyl)manzamine F [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 8-O-(4-bromobenzenesulfonyl)manzamine F. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-O-(4-bromobenzenesulfonyl)manzamine F through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
8-O-(4-chlorobenzenesulfonyl)manzamine F [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 8-O-(4-chlorobenzenesulfonyl)manzamine F. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-O-(4-chlorobenzenesulfonyl)manzamine F through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [532] | ||
8-O-(4-toluenesulfonyl)manzamine A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 8-O-(4-toluenesulfonyl)manzamine A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-O-(4-toluenesulfonyl)manzamine A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [532] | ||
8-OH-MANZAMINE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 8-OH-MANZAMINE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-OH-MANZAMINE A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [188], [519] | ||
9-N-ETHYL-8-ETHOXY-MANZAMINE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 9-N-ETHYL-8-ETHOXY-MANZAMINE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-N-ETHYL-8-ETHOXY-MANZAMINE A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
9-N-METHYL-8-METHOXY-MANZAMINE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for 9-N-METHYL-8-METHOXY-MANZAMINE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-N-METHYL-8-METHOXY-MANZAMINE A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
alsterpaullone 2-cyanoethyl [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for alsterpaullone 2-cyanoethyl. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of alsterpaullone 2-cyanoethyl through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [215], [519] | ||
AMP-PNP [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for AMP-PNP. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMP-PNP through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [225], [519] | ||
AS-601245 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for AS-601245. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AS-601245 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [533] | ||
AZAKENPAULLONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for AZAKENPAULLONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZAKENPAULLONE through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [534] | ||
Bisindolylmaleimide-I [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Bisindolylmaleimide-I. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bisindolylmaleimide-I through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [534] | ||
BX-795 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for BX-795. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BX-795 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [215], [519] | ||
BX-912 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for BX-912. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BX-912 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [213], [519] | ||
CHIR-98014 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for CHIR-98014. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHIR-98014 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [148], [519] | ||
CHIR-98023 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for CHIR-98023. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHIR-98023 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
CI-1040 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for CI-1040. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CI-1040 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [536] | ||
CP-70949 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for CP-70949. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CP-70949 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [537] | ||
CT-98024 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for CT-98024. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CT-98024 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [538] | ||
DM-204 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for DM-204. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DM-204 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [521] | ||
ELLAGIC ACID [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for ELLAGIC ACID. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ELLAGIC ACID through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [528] | ||
GSK-3beta inhibitor II [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for GSK-3beta inhibitor II. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-3beta inhibitor II through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [539] | ||
GSK-3beta inhibitor XI [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for GSK-3beta inhibitor XI. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-3beta inhibitor XI through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [227], [519] | ||
I-5 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for I-5. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of I-5 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [78], [519] | ||
IM-12 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for IM-12. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IM-12 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [540] | ||
indirubin deriv. 8a [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for indirubin deriv. 8a. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of indirubin deriv. 8a through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [541] | ||
K00244 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for K00244. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of K00244 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [542] | ||
L-779450 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for L-779450. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-779450 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [543] | ||
LEUCETTAMINE B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for LEUCETTAMINE B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LEUCETTAMINE B through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [544] | ||
MANZAMINE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for MANZAMINE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MANZAMINE A through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
Manzamine E [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Manzamine E. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Manzamine E through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [527] | ||
Manzamine Y [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Manzamine Y. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Manzamine Y through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [532] | ||
N,8-diphenyl-9H-purin-6-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N,8-diphenyl-9H-purin-6-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,8-diphenyl-9H-purin-6-amine through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [532] | ||
N-(6-(2-chlorophenyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(2-chlorophenyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(2-chlorophenyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-(3-hydroxyphenyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(3-hydroxyphenyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(3-hydroxyphenyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-(4-aminophenyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(4-aminophenyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(4-aminophenyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-(4-fluorophenyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(4-fluorophenyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(4-fluorophenyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(4-hydroxyphenyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-(furan-3-yl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(furan-3-yl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(furan-3-yl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-(pyridin-3-yl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(pyridin-3-yl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(pyridin-3-yl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [545] | ||
N-(6-(pyridin-4-yl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(pyridin-4-yl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(pyridin-4-yl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [544] | ||
N-(6-(thiophen-3-yl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(thiophen-3-yl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(thiophen-3-yl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [526] | ||
N-(6-(trifluoromethyl)-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-(trifluoromethyl)-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-(trifluoromethyl)-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-benzyl-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-benzyl-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-benzyl-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-bromo-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-bromo-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-bromo-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-chloro-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-chloro-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-chloro-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-chloro-5-p-tolyl-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-chloro-5-p-tolyl-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-chloro-5-p-tolyl-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-chloro-5-phenyl-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-chloro-5-phenyl-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-chloro-5-phenyl-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(6-phenethyl-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-phenethyl-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-phenethyl-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [526] | ||
N-(6-phenyl-1H-indazol-3-yl)butyramide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(6-phenyl-1H-indazol-3-yl)butyramide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(6-phenyl-1H-indazol-3-yl)butyramide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
N-(8-(3-cyanophenyl)-9H-purin-6-yl)pentanamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for N-(8-(3-cyanophenyl)-9H-purin-6-yl)pentanamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(8-(3-cyanophenyl)-9H-purin-6-yl)pentanamide through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [528] | ||
Neo-kauluamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Neo-kauluamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Neo-kauluamine through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [224], [519] | ||
NU-6102 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for NU-6102. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NU-6102 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [195], [519] | ||
PAULLONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for PAULLONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PAULLONE through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [520] | ||
PF-228 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for PF-228. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-228 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [535] | ||
PYRAZOLOPYRIDAZINE 1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for PYRAZOLOPYRIDAZINE 1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PYRAZOLOPYRIDAZINE 1 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [225], [519] | ||
PYRAZOLOPYRIDAZINE 2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for PYRAZOLOPYRIDAZINE 2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PYRAZOLOPYRIDAZINE 2 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [544] | ||
Quinoxaline1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Quinoxaline1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Quinoxaline1 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [546] | ||
RGB-286147 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for RGB-286147. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RGB-286147 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [213], [519] | ||
Ro31-8220 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Ro31-8220. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro31-8220 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [547] | ||
SB-415286 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for SB-415286. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SB-415286 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [531] | ||
STAUROSPORINONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for STAUROSPORINONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of STAUROSPORINONE through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [548] | ||
Thieno analogue of kenpaullone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for Thieno analogue of kenpaullone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Thieno analogue of kenpaullone through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [549] | ||
TWS-119 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for TWS-119. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TWS-119 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [550] | ||
AZD-1080 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for AZD-1080. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD-1080 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [551] | ||
RO-320432 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for RO-320432. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RO-320432 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [229], [519] | ||
SAN-61 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Glycogen synthase kinase-3 beta (GSK-3B) is a therapeutic target for SAN-61. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SAN-61 through regulating the expression of Glycogen synthase kinase-3 beta (GSK-3B). | [519], [552] | ||
Heat shock protein 90 alpha (HSP90A)
Amlexanox [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Amlexanox. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Amlexanox through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
Cromoglicate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Cromoglicate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cromoglicate through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
BIIB-021 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for BIIB-021. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BIIB-021 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [554] | ||
Efungumab [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Efungumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Efungumab through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
KW-2478 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for KW-2478. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KW-2478 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [556] | ||
NVP-AUY922 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for NVP-AUY922. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NVP-AUY922 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [557] | ||
SNX-5422 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for SNX-5422. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SNX-5422 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
Tanespimycin [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Tanespimycin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tanespimycin through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [558] | ||
VER 50589 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for VER 50589. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VER 50589 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [559] | ||
Alvespimycin hydrochloride [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Alvespimycin hydrochloride. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Alvespimycin hydrochloride through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [560] | ||
AT13387 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for AT13387. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AT13387 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
BIIB 028 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for BIIB 028. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BIIB 028 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [522], [553] | ||
Debio 0932 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Debio 0932. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Debio 0932 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [561] | ||
PU-AD [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for PU-AD. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PU-AD through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [556] | ||
PU3 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for PU3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PU3 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [562] | ||
RTA-901 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for RTA-901. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RTA-901 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [563] | ||
CCT-018159 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for CCT-018159. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CCT-018159 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [405], [553] | ||
KOS-2484 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for KOS-2484. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KOS-2484 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
17-desmethoxy-17-aminogeldanamycin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 17-desmethoxy-17-aminogeldanamycin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 17-desmethoxy-17-aminogeldanamycin through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [376], [553] | ||
2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
2-Methyl-2,4-Pentanediol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 2-Methyl-2,4-Pentanediol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Methyl-2,4-Pentanediol through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [78], [553] | ||
Geldanamycin-estradiol hybrid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Geldanamycin-estradiol hybrid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Geldanamycin-estradiol hybrid through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [564] | ||
GNF-PF-67 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for GNF-PF-67. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GNF-PF-67 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [376], [553] | ||
KOSN1559 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for KOSN1559. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KOSN1559 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [555] | ||
Macbecin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Macbecin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Macbecin through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [565] | ||
PU24S [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for PU24S. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PU24S through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [148], [553] | ||
Radicicol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Radicicol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Radicicol through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [566] | ||
RHEIN [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for RHEIN. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RHEIN through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [567] | ||
SNX-2112 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for SNX-2112. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SNX-2112 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [564] | ||
VER-49009 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for VER-49009. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VER-49009 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [452], [553] | ||
ZEARALANONE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for ZEARALANONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZEARALANONE through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [376], [553] | ||
EC-154 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for EC-154. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of EC-154 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [568] | ||
Geldanamycin [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for Geldanamycin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Geldanamycin through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [569] | ||
HBP-347 [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for HBP-347. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HBP-347 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [570] | ||
IPI-493 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Heat shock protein 90 alpha (HSP90A) is a therapeutic target for IPI-493. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IPI-493 through regulating the expression of Heat shock protein 90 alpha (HSP90A). | [553], [571] | ||
Herpesvirus ubiquitin-specific protease (HAUSP)
ADC-01 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Herpesvirus ubiquitin-specific protease (HAUSP) is a therapeutic target for ADC-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ADC-01 through regulating the expression of Herpesvirus ubiquitin-specific protease (HAUSP). | [572], [573] | ||
ADC-03 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Herpesvirus ubiquitin-specific protease (HAUSP) is a therapeutic target for ADC-03. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ADC-03 through regulating the expression of Herpesvirus ubiquitin-specific protease (HAUSP). | [572], [574] | ||
HBX19818 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Herpesvirus ubiquitin-specific protease (HAUSP) is a therapeutic target for HBX19818. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HBX19818 through regulating the expression of Herpesvirus ubiquitin-specific protease (HAUSP). | [572], [575] | ||
P22077 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Herpesvirus ubiquitin-specific protease (HAUSP) is a therapeutic target for P22077. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of P22077 through regulating the expression of Herpesvirus ubiquitin-specific protease (HAUSP). | [572], [576] | ||
Histone-lysine N-methyltransferase EHMT2 (EHMT2)
A-366 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for A-366. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of A-366 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [578] | ||
BIX-01294 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for BIX-01294. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BIX-01294 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [579] | ||
MS012 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for MS012. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MS012 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [580] | ||
BRD9539 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for BRD9539. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BRD9539 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [581] | ||
UNC0321 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for UNC0321. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of UNC0321 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [582] | ||
UNC0638 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for UNC0638. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of UNC0638 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [583] | ||
UNC0642 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Histone-lysine N-methyltransferase EHMT2 (EHMT2) is a therapeutic target for UNC0642. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of UNC0642 through regulating the expression of Histone-lysine N-methyltransferase EHMT2 (EHMT2). | [577], [584] | ||
Integrin beta-1 (ITGB1)
131I-radretumab [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Integrin beta-1 (ITGB1) is a therapeutic target for 131I-radretumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 131I-radretumab through regulating the expression of Integrin beta-1 (ITGB1). | [585], [586] | ||
JSM 6427 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Integrin beta-1 (ITGB1) is a therapeutic target for JSM 6427. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of JSM 6427 through regulating the expression of Integrin beta-1 (ITGB1). | [585], [587] | ||
OS2966 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Integrin beta-1 (ITGB1) is a therapeutic target for OS2966. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OS2966 through regulating the expression of Integrin beta-1 (ITGB1). | [585], [588] | ||
C(-GRGDfL-) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Integrin beta-1 (ITGB1) is a therapeutic target for C(-GRGDfL-). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C(-GRGDfL-) through regulating the expression of Integrin beta-1 (ITGB1). | [585], [589] | ||
MK-0668 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Integrin beta-1 (ITGB1) is a therapeutic target for MK-0668. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-0668 through regulating the expression of Integrin beta-1 (ITGB1). | [585], [590] | ||
SB-265123 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Integrin beta-1 (ITGB1) is a therapeutic target for SB-265123. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SB-265123 through regulating the expression of Integrin beta-1 (ITGB1). | [585], [591] | ||
Intercellular adhesion molecule ICAM-1 (ICAM1)
ISIS 1570 [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 1570. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 1570 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [593] | ||
lifitegrast [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for lifitegrast. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of lifitegrast through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [594] | ||
Alicaforsen [Phase 3]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for Alicaforsen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Alicaforsen through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [595] | ||
Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for Alicaforsen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Alicaforsen through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [596] | |||
APC-8015F [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for APC-8015F. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of APC-8015F through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [597] | ||
BI-505 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for BI-505. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BI-505 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [598] | ||
AIC100 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for AIC100. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AIC100 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [599] | ||
A-286982 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for A-286982. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of A-286982 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [600] | ||
Dehydropipernonaline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for Dehydropipernonaline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dehydropipernonaline through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [600] | ||
ISIS 11158 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 11158. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 11158 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [601] | ||
ISIS 11159 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 11159. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 11159 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [602] | ||
ISIS 11665 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 11665. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 11665 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [602] | ||
ISIS 1931 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 1931. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 1931 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [595] | ||
ISIS 2974 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 2974. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 2974 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [602] | ||
ISIS 3067 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 3067. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 3067 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [602] | ||
ISIS 3224 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS 3224. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 3224 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [602] | ||
ISIS-1939 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for ISIS-1939. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS-1939 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [603] | ||
Pellitorin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for Pellitorin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pellitorin through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [600] | ||
PIPERNONALINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for PIPERNONALINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PIPERNONALINE through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [604] | ||
PIPERROLEIN B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for PIPERROLEIN B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PIPERROLEIN B through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [600] | ||
A-252444.0 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for A-252444.0. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of A-252444.0 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [605] | ||
GI-270384X [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for GI-270384X. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GI-270384X through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [606] | ||
INXC-ICAM1 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for INXC-ICAM1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INXC-ICAM1 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [595] | ||
MOR-102 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Intercellular adhesion molecule ICAM-1 (ICAM1) is a therapeutic target for MOR-102. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MOR-102 through regulating the expression of Intercellular adhesion molecule ICAM-1 (ICAM1). | [592], [607] | ||
Janus kinase 2 (JAK-2)
Baricitinib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Baricitinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Baricitinib through regulating the expression of Janus kinase 2 (JAK-2). | [608], [609] | ||
Fedratinib [Approved]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Fedratinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Fedratinib through regulating the expression of Janus kinase 2 (JAK-2). | [608], [610] | ||
Janus kinase 2 (JAK-2) is a therapeutic target for Fedratinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Fedratinib through regulating the expression of Janus kinase 2 (JAK-2). | [608], [628] | |||
Ruxolitinib [Approved]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Ruxolitinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ruxolitinib through regulating the expression of Janus kinase 2 (JAK-2). | [608], [611] | ||
Janus kinase 2 (JAK-2) is a therapeutic target for Ruxolitinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ruxolitinib through regulating the expression of Janus kinase 2 (JAK-2). | [114], [608] | |||
CYT-387 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for CYT-387. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CYT-387 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [612] | ||
ITF2357 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for ITF2357. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ITF2357 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [613] | ||
Pacritinib [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Pacritinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pacritinib through regulating the expression of Janus kinase 2 (JAK-2). | [608], [614] | ||
XL019 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for XL019. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of XL019 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [615] | ||
AZD1480 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for AZD1480. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD1480 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [616] | ||
BMS-911543 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for BMS-911543. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-911543 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [617] | ||
Cerdulatinib [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Cerdulatinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cerdulatinib through regulating the expression of Janus kinase 2 (JAK-2). | [608], [618] | ||
CTP-543 [Phase 2]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for CTP-543. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CTP-543 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [619] | ||
Janus kinase 2 (JAK-2) is a therapeutic target for CTP-543. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CTP-543 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [615] | |||
INCB039110 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for INCB039110. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INCB039110 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [620] | ||
LY2784544 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for LY2784544. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY2784544 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [621] | ||
NS-018 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for NS-018. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NS-018 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [619] | ||
AC430 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for AC430. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AC430 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [622] | ||
Peginterferon beta [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Peginterferon beta. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Peginterferon beta through regulating the expression of Janus kinase 2 (JAK-2). | [608], [611] | ||
SB-1578 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for SB-1578. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SB-1578 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [623] | ||
1,2,3,4,5,6-hexabromocyclohexane [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for 1,2,3,4,5,6-hexabromocyclohexane. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1,2,3,4,5,6-hexabromocyclohexane through regulating the expression of Janus kinase 2 (JAK-2). | [608], [624] | ||
5-phenyl-1H-indazol-3-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for 5-phenyl-1H-indazol-3-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-phenyl-1H-indazol-3-amine through regulating the expression of Janus kinase 2 (JAK-2). | [608], [625] | ||
AMG-JAK2-01 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for AMG-JAK2-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMG-JAK2-01 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [619] | ||
Atropisomer 1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for Atropisomer 1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Atropisomer 1 through regulating the expression of Janus kinase 2 (JAK-2). | [376], [608] | ||
AZ960 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for AZ960. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZ960 through regulating the expression of Janus kinase 2 (JAK-2). | [78], [608] | ||
BVB-808 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for BVB-808. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BVB-808 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [626] | ||
CMP-6 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for CMP-6. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CMP-6 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [627] | ||
K-454 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for K-454. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of K-454 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [629] | ||
NSC-1771 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for NSC-1771. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NSC-1771 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [630] | ||
ON-044580 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for ON-044580. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ON-044580 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [619] | ||
SGI-1252 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for SGI-1252. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SGI-1252 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [631] | ||
WHI-P154 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for WHI-P154. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of WHI-P154 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [632] | ||
AG490 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Janus kinase 2 (JAK-2) is a therapeutic target for AG490. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AG490 through regulating the expression of Janus kinase 2 (JAK-2). | [608], [611] | ||
Leukocyte immunoglobulin-like receptor B4 (LILRB4)
IO-202 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Leukocyte immunoglobulin-like receptor B4 (LILRB4) is a therapeutic target for IO-202. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IO-202 through regulating the expression of Leukocyte immunoglobulin-like receptor B4 (LILRB4). | [633], [634] | ||
Mammalian target of rapamycin complex 1 (mTORC1)
RBT-101 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Mammalian target of rapamycin complex 1 (mTORC1) is a therapeutic target for RBT-101. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RBT-101 through regulating the expression of Mammalian target of rapamycin complex 1 (mTORC1). | [635], [636] | ||
AZD-2014 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Mammalian target of rapamycin complex 1 (mTORC1) is a therapeutic target for AZD-2014. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD-2014 through regulating the expression of Mammalian target of rapamycin complex 1 (mTORC1). | [635], [637] | ||
ME-344 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Mammalian target of rapamycin complex 1 (mTORC1) is a therapeutic target for ME-344. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ME-344 through regulating the expression of Mammalian target of rapamycin complex 1 (mTORC1). | [38], [635] | ||
NV-5138 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Mammalian target of rapamycin complex 1 (mTORC1) is a therapeutic target for NV-5138. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NV-5138 through regulating the expression of Mammalian target of rapamycin complex 1 (mTORC1). | [635], [638] | ||
Palomid-529 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Mammalian target of rapamycin complex 1 (mTORC1) is a therapeutic target for Palomid-529. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Palomid-529 through regulating the expression of Mammalian target of rapamycin complex 1 (mTORC1). | [38], [635] | ||
VS-5584 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Mammalian target of rapamycin complex 1 (mTORC1) is a therapeutic target for VS-5584. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VS-5584 through regulating the expression of Mammalian target of rapamycin complex 1 (mTORC1). | [635], [639] | ||
Matrix metalloproteinase-13 (MMP-13)
Curcumin [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for Curcumin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Curcumin through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [641] | ||
Apratastat [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for Apratastat. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Apratastat through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [642] | ||
PMID17935984C1 [Clinical trial]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for PMID17935984C1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PMID17935984C1 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [643] | ||
1-(4-Methoxy-benzenesulfonyl)-heptane-3-thiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 1-(4-Methoxy-benzenesulfonyl)-heptane-3-thiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(4-Methoxy-benzenesulfonyl)-heptane-3-thiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [644] | ||
1-Methyloxy-4-Sulfone-Benzene [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 1-Methyloxy-4-Sulfone-Benzene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Methyloxy-4-Sulfone-Benzene through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [645] | ||
2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [646] | ||
2-(biphenyl-4-ylsulfonamido)pentanedioic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 2-(biphenyl-4-ylsulfonamido)pentanedioic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(biphenyl-4-ylsulfonamido)pentanedioic acid through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [642] | ||
2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [647] | ||
3-(4-Methoxy-benzenesulfonyl)-cyclohexanethiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Methoxy-benzenesulfonyl)-cyclohexanethiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Methoxy-benzenesulfonyl)-cyclohexanethiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [648] | ||
3-(4-Methoxy-benzenesulfonyl)-cyclopentanethiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Methoxy-benzenesulfonyl)-cyclopentanethiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Methoxy-benzenesulfonyl)-cyclopentanethiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [649] | ||
3-(4-Methoxy-benzenesulfonyl)-hexane-1-thiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Methoxy-benzenesulfonyl)-hexane-1-thiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Methoxy-benzenesulfonyl)-hexane-1-thiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [650] | ||
3-(4-Methoxy-benzenesulfonyl)-pentane-1-thiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Methoxy-benzenesulfonyl)-pentane-1-thiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Methoxy-benzenesulfonyl)-pentane-1-thiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [644] | ||
3-(4-Methoxy-benzenesulfonyl)-propane-1-thiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Methoxy-benzenesulfonyl)-propane-1-thiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Methoxy-benzenesulfonyl)-propane-1-thiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [651] | ||
3-(4-Phenoxy-benzenesulfonyl)-cyclohexanethiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Phenoxy-benzenesulfonyl)-cyclohexanethiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Phenoxy-benzenesulfonyl)-cyclohexanethiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [644] | ||
3-(4-Phenoxy-benzenesulfonyl)-propane-1-thiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-(4-Phenoxy-benzenesulfonyl)-propane-1-thiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Phenoxy-benzenesulfonyl)-propane-1-thiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [644] | ||
3-Benzenesulfonyl-heptanoic acid hydroxyamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-Benzenesulfonyl-heptanoic acid hydroxyamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Benzenesulfonyl-heptanoic acid hydroxyamide through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [645] | ||
3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [651] | ||
3-Methylpyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 3-Methylpyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Methylpyridine through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [148], [640] | ||
4-(2,2'-bithiophen-5-ylmethyleneamino)phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 4-(2,2'-bithiophen-5-ylmethyleneamino)phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2,2'-bithiophen-5-ylmethyleneamino)phenol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [652] | ||
4-(4-Methoxy-benzenesulfonyl)-butane-2-thiol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 4-(4-Methoxy-benzenesulfonyl)-butane-2-thiol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(4-Methoxy-benzenesulfonyl)-butane-2-thiol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [651] | ||
4-(methyl(4-phenylthiazol-2-yl)amino)phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 4-(methyl(4-phenylthiazol-2-yl)amino)phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(methyl(4-phenylthiazol-2-yl)amino)phenol through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [653] | ||
4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [642] | ||
5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for 5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [654] | ||
CL82198 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for CL82198. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CL82198 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [655] | ||
Ethyl 2-cyano-2-(quinoxalin-2(1H)-ylidene)acetate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for Ethyl 2-cyano-2-(quinoxalin-2(1H)-ylidene)acetate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ethyl 2-cyano-2-(quinoxalin-2(1H)-ylidene)acetate through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [653] | ||
Hydroxyaminovaline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for Hydroxyaminovaline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Hydroxyaminovaline through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [148], [640] | ||
IK-862 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for IK-862. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IK-862 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [644] | ||
MMI270 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for MMI270. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MMI270 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [656] | ||
N-Hydroxy-2-(4-phenoxy-benzenesulfonyl)benzamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for N-Hydroxy-2-(4-phenoxy-benzenesulfonyl)benzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-Hydroxy-2-(4-phenoxy-benzenesulfonyl)benzamide through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [646] | ||
N1,N3-bis(3-methoxybenzyl)isophthalamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for N1,N3-bis(3-methoxybenzyl)isophthalamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N1,N3-bis(3-methoxybenzyl)isophthalamide through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [657] | ||
N4,N6-dibenzylpyrimidine-4,6-dicarboxamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for N4,N6-dibenzylpyrimidine-4,6-dicarboxamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N4,N6-dibenzylpyrimidine-4,6-dicarboxamide through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [642] | ||
PD-156 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for PD-156. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-156 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [658] | ||
PKF-242-484 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for PKF-242-484. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PKF-242-484 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [659] | ||
Ro-37-9790 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for Ro-37-9790. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro-37-9790 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [644] | ||
SL422 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for SL422. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SL422 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [660] | ||
SR-973 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for SR-973. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SR-973 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [647] | ||
UK-356618 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for UK-356618. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of UK-356618 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [148], [640] | ||
WAY-151693 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for WAY-151693. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of WAY-151693 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [148], [640] | ||
WAY170523 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for WAY170523. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of WAY170523 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [660] | ||
[2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for [2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [647] | ||
GM6001 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for GM6001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GM6001 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [661] | ||
RS-130830 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Matrix metalloproteinase-13 (MMP-13) is a therapeutic target for RS-130830. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RS-130830 through regulating the expression of Matrix metalloproteinase-13 (MMP-13). | [640], [662] | ||
Melanocortin receptor 4 (MC4R)
Amylin [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Amylin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Amylin through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [664] | ||
Bremelanotide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Bremelanotide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bremelanotide through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [665] | ||
Methylnaltrexone bromide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Methylnaltrexone bromide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Methylnaltrexone bromide through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [666] | ||
Setmelanotide [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Setmelanotide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Setmelanotide through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [667] | ||
AMG 386 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for AMG 386. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMG 386 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [668] | ||
AP-1030 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for AP-1030. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AP-1030 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [669] | ||
PF-446687 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for PF-446687. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-446687 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [670] | ||
PMX-53 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for PMX-53. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PMX-53 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [667] | ||
IDDBCP-150101 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for IDDBCP-150101. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IDDBCP-150101 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [667] | ||
Melanotetan II [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Melanotetan II. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Melanotetan II through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [667] | ||
Ro-27-3225 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ro-27-3225. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro-27-3225 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [671] | ||
1-Benzyl-4-methyl-piperazine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for 1-Benzyl-4-methyl-piperazine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Benzyl-4-methyl-piperazine through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [672] | ||
1-Methyl-4-(1-phenyl-ethyl)-piperazine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for 1-Methyl-4-(1-phenyl-ethyl)-piperazine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Methyl-4-(1-phenyl-ethyl)-piperazine through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for 4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [667] | ||
Ac-dR[CEHdFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-dR[CEHdFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-dR[CEHdFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [674] | ||
Ac-His-D-Phe-Arg-2-Nal-NHCH3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-His-D-Phe-Arg-2-Nal-NHCH3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-His-D-Phe-Arg-2-Nal-NHCH3 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
Ac-His-DPhe-Arg-Trp-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-His-DPhe-Arg-Trp-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-His-DPhe-Arg-Trp-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [676] | ||
Ac-Nle-c[Asp-His-DNaI(2')-Pro-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-Nle-c[Asp-His-DNaI(2')-Pro-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-Nle-c[Asp-His-DNaI(2')-Pro-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [677] | ||
Ac-Nle-c[Asp-His-DNal(2')-Pro-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-Nle-c[Asp-His-DNal(2')-Pro-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-Nle-c[Asp-His-DNal(2')-Pro-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [678] | ||
AC-Nle-c[Asp-His-DPhe-Pro-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for AC-Nle-c[Asp-His-DPhe-Pro-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AC-Nle-c[Asp-His-DPhe-Pro-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [679] | ||
Ac-R[CEHdFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-R[CEHdFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-R[CEHdFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-Tyr-D-Phe-Arg-2-Nal-NHCH3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-Tyr-D-Phe-Arg-2-Nal-NHCH3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-Tyr-D-Phe-Arg-2-Nal-NHCH3 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [680] | ||
Ac-YCit[CEHdFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YCit[CEHdFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YCit[CEHdFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YK[CEHdFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YK[CEHdFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YK[CEHdFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YRC(Me)*EHdFRWC(Me)NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YRC(Me)*EHdFRWC(Me)NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YRC(Me)*EHdFRWC(Me)NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YRMEHdFRWG-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YRMEHdFRWG-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YRMEHdFRWG-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YRMEHdFRWGSPPKD-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YRMEHdFRWGSPPKD-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YRMEHdFRWGSPPKD-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CE(1-Me-H)dFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CE(1-Me-H)dFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CE(1-Me-H)dFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CEH(pCl-dF)RWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CEH(pCl-dF)RWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CEH(pCl-dF)RWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CEH(pF-dF)RWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CEH(pF-dF)RWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CEH(pF-dF)RWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CEHdFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CEHdFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CEHdFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CEHdFRWC]SPPKD-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CEHdFRWC]SPPKD-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CEHdFRWC]SPPKD-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-YR[CEHFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-YR[CEHFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-YR[CEHFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ac-[CEHdFRWC]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ac-[CEHdFRWC]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ac-[CEHdFRWC]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
AEKKDEGPYRMEHFRWGSPPKD [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for AEKKDEGPYRMEHFRWGSPPKD. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AEKKDEGPYRMEHFRWGSPPKD through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
AMSH [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for AMSH. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AMSH through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [681] | ||
BL-6020 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for BL-6020. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BL-6020 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [682] | ||
C(his-D-phe-arg-trp-Abu) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C(his-D-phe-arg-trp-Abu). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C(his-D-phe-arg-trp-Abu) through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [683] | ||
C(his-D-phe-arg-trp-Ahp) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C(his-D-phe-arg-trp-Ahp). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C(his-D-phe-arg-trp-Ahp) through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [683] | ||
C(his-D-phe-arg-trp-Ahx) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C(his-D-phe-arg-trp-Ahx). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C(his-D-phe-arg-trp-Ahx) through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [683] | ||
C(his-D-phe-arg-trp-Aoc) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C(his-D-phe-arg-trp-Aoc). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C(his-D-phe-arg-trp-Aoc) through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [684] | ||
C(his-L-phe-arg-trp-Aoc) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C(his-L-phe-arg-trp-Aoc). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C(his-L-phe-arg-trp-Aoc) through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [685] | ||
C[CO-(CH2)2-CO-Nle-D-Nal(2)-Arg-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[CO-(CH2)2-CO-Nle-D-Nal(2)-Arg-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[CO-(CH2)2-CO-Nle-D-Nal(2)-Arg-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [676] | ||
C[CO-(CH2)2-CO-Nle-D-Phe-Arg-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[CO-(CH2)2-CO-Nle-D-Phe-Arg-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[CO-(CH2)2-CO-Nle-D-Phe-Arg-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [676] | ||
C[CO-(CH2)3-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[CO-(CH2)3-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[CO-(CH2)3-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [676] | ||
C[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [676] | ||
C[CO-o-C6H4-CO-Pro-D-Phe-Arg-Trp-Lys]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[CO-o-C6H4-CO-Pro-D-Phe-Arg-Trp-Lys]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[CO-o-C6H4-CO-Pro-D-Phe-Arg-Trp-Lys]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [677] | ||
C[Nle-Arg-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Arg-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Arg-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Arg-D-Phe-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Arg-D-Phe-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Arg-D-Phe-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [670] | ||
C[Nle-Asp-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Asp-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Asp-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Asp-D-Phe-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Asp-D-Phe-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Asp-D-Phe-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [686] | ||
C[Nle-Gln-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Gln-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Gln-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Glu-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Glu-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Glu-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-His-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-His-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-His-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-His-D-Phe-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-His-D-Phe-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-His-D-Phe-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Nle-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Nle-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Nle-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Nle-D-Phe-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Nle-D-Phe-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Nle-D-Phe-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Pro-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Pro-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Pro-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Pro-D-Phe-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Pro-D-Phe-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Pro-D-Phe-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Val-D-Nal(2')-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Val-D-Nal(2')-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Val-D-Nal(2')-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Nle-Val-D-Phe-Arg-Trp-Glu]-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Nle-Val-D-Phe-Arg-Trp-Glu]-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Nle-Val-D-Phe-Arg-Trp-Glu]-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
C[Ser-Tyr-Thr-His-Dphe-Arg-Trp-Thr-Ile-Pro] [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Ser-Tyr-Thr-His-Dphe-Arg-Trp-Thr-Ile-Pro]. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Ser-Tyr-Thr-His-Dphe-Arg-Trp-Thr-Ile-Pro] through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [683] | ||
C[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for C[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro]. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [684] | ||
D-Phe-Arg-2-Nal-NHCH3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for D-Phe-Arg-2-Nal-NHCH3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of D-Phe-Arg-2-Nal-NHCH3 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [677] | ||
GPYRMEHFRWGSPPKD-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for GPYRMEHFRWGSPPKD-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GPYRMEHFRWGSPPKD-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [672] | ||
His-DPhe-Arg-Trp [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for His-DPhe-Arg-Trp. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of His-DPhe-Arg-Trp through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [686] | ||
Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [675] | ||
HS014 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for HS014. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HS014 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [687] | ||
MCL-129 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for MCL-129. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MCL-129 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [684] | ||
MCL0129 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for MCL0129. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MCL0129 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [688] | ||
Melanocortin-4 Receptor antagonist [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Melanocortin-4 Receptor antagonist. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Melanocortin-4 Receptor antagonist through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [689] | ||
MK-10 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for MK-10. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-10 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [690] | ||
MK-11 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for MK-11. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-11 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [674] | ||
ML-253764 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for ML-253764. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ML-253764 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
MT-II [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for MT-II. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MT-II through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [691] | ||
NDP-alpha-MSH [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for NDP-alpha-MSH. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NDP-alpha-MSH through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [692] | ||
NDP-SYSMEHFRWGKPVG [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for NDP-SYSMEHFRWGKPVG. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NDP-SYSMEHFRWGKPVG through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [673] | ||
Ser-Tyr-Ser-Nle-Glu-His-Dphe-Arg [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Ser-Tyr-Ser-Nle-Glu-His-Dphe-Arg. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ser-Tyr-Ser-Nle-Glu-His-Dphe-Arg through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [678] | ||
THIQ [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for THIQ. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of THIQ through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [691] | ||
Tic-D-Phe-Arg-2-Nal-NHCH3 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for Tic-D-Phe-Arg-2-Nal-NHCH3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tic-D-Phe-Arg-2-Nal-NHCH3 through regulating the expression of Melanocortin receptor 4 (MC4R). | [663], [683] | ||
PT-14 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Melanocortin receptor 4 (MC4R) is a therapeutic target for PT-14. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PT-14 through regulating the expression of Melanocortin receptor 4 (MC4R). | [166], [663] | ||
Methylenetetrahydrofolate reductase (MTHFR)
Benazepril [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for Benazepril. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Benazepril through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [693] | ||
Folic acid [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for Folic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Folic acid through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [694] | ||
Menadione [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for Menadione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Menadione through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [695] | ||
Methotrexate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for Methotrexate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Methotrexate through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [696] | ||
ISO-901 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for ISO-901. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISO-901 through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [697] | ||
677T [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for 677T. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 677T through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [698] | ||
EX5 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Methylenetetrahydrofolate reductase (MTHFR) is a therapeutic target for EX5. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of EX5 through regulating the expression of Methylenetetrahydrofolate reductase (MTHFR). | [149], [699] | ||
microRNA hsa-miR-155 (MIR155)
Cobomarsen [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | microRNA hsa-miR-155 (MIR155) is a therapeutic target for Cobomarsen. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cobomarsen through regulating the expression of microRNA hsa-miR-155 (MIR155). | [700], [701] | ||
MRG-201 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | microRNA hsa-miR-155 (MIR155) is a therapeutic target for MRG-201. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MRG-201 through regulating the expression of microRNA hsa-miR-155 (MIR155). | [38], [700] | ||
Multidrug resistance-associated protein 7 (ABCC10)
Docetaxel [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Multidrug resistance-associated protein 7 (ABCC10) is a therapeutic target for Docetaxel. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Docetaxel through regulating the expression of Multidrug resistance-associated protein 7 (ABCC10). | [702], [703] | ||
Tenofovir [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Multidrug resistance-associated protein 7 (ABCC10) is a therapeutic target for Tenofovir. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tenofovir through regulating the expression of Multidrug resistance-associated protein 7 (ABCC10). | [702], [704] | ||
NAD-dependent deacetylase sirtuin-1 (SIRT1)
GSK2245840 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for GSK2245840. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK2245840 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [706] | ||
MB-12066 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for MB-12066. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MB-12066 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [707] | ||
SEN-196 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for SEN-196. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SEN-196 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [708] | ||
SRT2379 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for SRT2379. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SRT2379 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [709] | ||
SRT3025 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for SRT3025. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SRT3025 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [710] | ||
(R)-sirtinol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for (R)-sirtinol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (R)-sirtinol through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [711] | ||
(S)-sirtinol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for (S)-sirtinol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (S)-sirtinol through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [711] | ||
2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for 2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [712] | ||
2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for 2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [390], [705] | ||
Meta-sirtinol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for Meta-sirtinol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Meta-sirtinol through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [713] | ||
Para-sirtinol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for Para-sirtinol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Para-sirtinol through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [711] | ||
RO-316233 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for RO-316233. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RO-316233 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [712] | ||
Ro31-8220 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for Ro31-8220. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro31-8220 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [714] | ||
splitomicin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for splitomicin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of splitomicin through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [715] | ||
SRT1720 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for SRT1720. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SRT1720 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [711] | ||
YK-3237 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for YK-3237. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of YK-3237 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [714] | ||
GSK184072 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | NAD-dependent deacetylase sirtuin-1 (SIRT1) is a therapeutic target for GSK184072. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK184072 through regulating the expression of NAD-dependent deacetylase sirtuin-1 (SIRT1). | [705], [716] | ||
Nitric oxide synthase endothelial (NOS3)
Tilarginine acetate [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Tilarginine acetate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tilarginine acetate through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [717] | ||
ACCLAIM [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for ACCLAIM. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ACCLAIM through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [718] | ||
L-NAME [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for L-NAME. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-NAME through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [719] | ||
MTR105 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for MTR105. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MTR105 through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [720] | ||
VAS-203 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for VAS-203. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VAS-203 through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [721] | ||
Autologous cell based gene therapy [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Autologous cell based gene therapy. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Autologous cell based gene therapy through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [722] | ||
(5-Imino-[1,4]thiazepan-3-yl)-methanol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (5-Imino-[1,4]thiazepan-3-yl)-methanol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (5-Imino-[1,4]thiazepan-3-yl)-methanol through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
(5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [724] | ||
(5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [725] | ||
(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [78], [592] | ||
(S)-2-Amino-5-(N-methyl-guanidino)-pentanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (S)-2-Amino-5-(N-methyl-guanidino)-pentanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (S)-2-Amino-5-(N-methyl-guanidino)-pentanoic acid through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [724] | ||
(S)-3-Propyl-[1,4]thiazepan-(5E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (S)-3-Propyl-[1,4]thiazepan-(5E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (S)-3-Propyl-[1,4]thiazepan-(5E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
(S)-6-Amino-2-(2-imino-ethylamino)-hexanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for (S)-6-Amino-2-(2-imino-ethylamino)-hexanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (S)-6-Amino-2-(2-imino-ethylamino)-hexanoic acid through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
1,2,4-Triazole-Carboxamidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 1,2,4-Triazole-Carboxamidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1,2,4-Triazole-Carboxamidine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
1-(2-amino-benzothiazol-5-yl)-2-ethyl-isothiourea [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 1-(2-amino-benzothiazol-5-yl)-2-ethyl-isothiourea. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(2-amino-benzothiazol-5-yl)-2-ethyl-isothiourea through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [726] | ||
1-(2-amino-benzothiazol-6-yl)-2-ethyl-isothiourea [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 1-(2-amino-benzothiazol-6-yl)-2-ethyl-isothiourea. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-(2-amino-benzothiazol-6-yl)-2-ethyl-isothiourea through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [727] | ||
1400W [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 1400W. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1400W through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
2-amino-4-methylpyridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2-amino-4-methylpyridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-amino-4-methylpyridine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [728] | ||
2-Amino-5-(N-nitro-guanidino)-pentanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2-Amino-5-(N-nitro-guanidino)-pentanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Amino-5-(N-nitro-guanidino)-pentanoic acid through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [729] | ||
2-Aminothiazoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2-Aminothiazoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Aminothiazoline through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
2-Methyl-2,4-Pentanediol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2-Methyl-2,4-Pentanediol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Methyl-2,4-Pentanediol through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [729] | ||
2-Methyl-[1,4]thiazepan-(5E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2-Methyl-[1,4]thiazepan-(5E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Methyl-[1,4]thiazepan-(5E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
2-Propanol, Isopropanol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 2-Propanol, Isopropanol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Propanol, Isopropanol through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [78], [592] | ||
3,4-Dimethyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 3,4-Dimethyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3,4-Dimethyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
3-Bromo-1H-indazole-7-carbonitrile [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 3-Bromo-1H-indazole-7-carbonitrile. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Bromo-1H-indazole-7-carbonitrile through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [731] | ||
3-bromo-7-nitro-1H-indazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 3-bromo-7-nitro-1H-indazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-bromo-7-nitro-1H-indazole through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [78], [592] | ||
3-Ethyl-[1,4]thiazepan-(5E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 3-Ethyl-[1,4]thiazepan-(5E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Ethyl-[1,4]thiazepan-(5E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
3-Methyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 3-Methyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Methyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
3-Methyl-[1,4]thiazepan-(5E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 3-Methyl-[1,4]thiazepan-(5E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Methyl-[1,4]thiazepan-(5E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
4,5-Dimethyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4,5-Dimethyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4,5-Dimethyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
4-Ethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Ethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Ethyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [727] | ||
4-Ethyl-5-methyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Ethyl-5-methyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Ethyl-5-methyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
4-Ethyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Ethyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Ethyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Methyl-3,6-dihydro-1H-pyridin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [732] | ||
4-Methyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Methyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Methyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [732] | ||
4-methyl-6-propylpyridin-2-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-methyl-6-propylpyridin-2-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-methyl-6-propylpyridin-2-amine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [731] | ||
4-Methyl-piperidin-(2E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Methyl-piperidin-(2E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Methyl-piperidin-(2E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [724] | ||
4-Methyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 4-Methyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Methyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
5,6-Cyclic-Tetrahydropteridine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 5,6-Cyclic-Tetrahydropteridine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,6-Cyclic-Tetrahydropteridine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
5-Ethyl-3-methyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 5-Ethyl-3-methyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Ethyl-3-methyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
5-Ethyl-4-methyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 5-Ethyl-4-methyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Ethyl-4-methyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
5-Methyl-pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 5-Methyl-pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Methyl-pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
5-Nitroindazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 5-Nitroindazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Nitroindazole through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
6-(2-Fluoropropyl)-4-methylpyridin-2-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 6-(2-Fluoropropyl)-4-methylpyridin-2-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(2-Fluoropropyl)-4-methylpyridin-2-amine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [726] | ||
6-(3-Fluoropropyl)-4-methylpyridin-2-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 6-(3-Fluoropropyl)-4-methylpyridin-2-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-(3-Fluoropropyl)-4-methylpyridin-2-amine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [733] | ||
6-isobutyl-4-methylpyridin-2-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 6-isobutyl-4-methylpyridin-2-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-isobutyl-4-methylpyridin-2-amine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [726] | ||
6-Nitroindazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 6-Nitroindazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Nitroindazole through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
6s-5,6,7,8-Tetrahydrobiopterin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 6s-5,6,7,8-Tetrahydrobiopterin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6s-5,6,7,8-Tetrahydrobiopterin through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
7-(2-Nitro-ethyl)-azepan-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 7-(2-Nitro-ethyl)-azepan-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-(2-Nitro-ethyl)-azepan-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [732] | ||
7-Methyl-[1,4]thiazepan-(5E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 7-Methyl-[1,4]thiazepan-(5E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Methyl-[1,4]thiazepan-(5E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
7-nitro-1H-indazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 7-nitro-1H-indazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-nitro-1H-indazole through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
7-Nitroindazole-2-Carboxamidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for 7-Nitroindazole-2-Carboxamidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Nitroindazole-2-Carboxamidine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [155], [592] | ||
Acetate Ion [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Acetate Ion. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Acetate Ion through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [734] | ||
AP-Cav [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for AP-Cav. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AP-Cav through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [724] | ||
Azepan-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Azepan-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Azepan-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [729] | ||
Cacodylate Ion [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Cacodylate Ion. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cacodylate Ion through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
Ethylisothiourea [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Ethylisothiourea. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ethylisothiourea through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
Heme [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Heme. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Heme through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
Hexahydro-cyclopenta[c]pyrrol-(1Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Hexahydro-cyclopenta[c]pyrrol-(1Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Hexahydro-cyclopenta[c]pyrrol-(1Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
Hydroxydimethylarsine Oxide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Hydroxydimethylarsine Oxide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Hydroxydimethylarsine Oxide through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [78], [592] | ||
L-2-Amino-4-(Guanidinooxy)Butyric Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for L-2-Amino-4-(Guanidinooxy)Butyric Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-2-Amino-4-(Guanidinooxy)Butyric Acid through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
L-Homoarginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for L-Homoarginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Homoarginine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
L-NIO [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for L-NIO. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-NIO through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [155], [592] | ||
N,N-dimethylarginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N,N-dimethylarginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N,N-dimethylarginine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
N-(5-Amino-6-oxo-heptyl)-acetamidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N-(5-Amino-6-oxo-heptyl)-acetamidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(5-Amino-6-oxo-heptyl)-acetamidine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
N-(Chlorophenyl)-N'-Hydroxyguanidine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N-(Chlorophenyl)-N'-Hydroxyguanidine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-(Chlorophenyl)-N'-Hydroxyguanidine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [735] | ||
N-omega-allyl-L-arginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N-omega-allyl-L-arginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-omega-allyl-L-arginine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [733] | ||
N-Omega-Hydroxy-L-Arginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N-Omega-Hydroxy-L-Arginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-Omega-Hydroxy-L-Arginine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
N-omega-propargyl-L-arginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N-omega-propargyl-L-arginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-omega-propargyl-L-arginine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [736] | ||
N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
N5-(1-iminobut-3-enyl)-L-ornithine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N5-(1-iminobut-3-enyl)-L-ornithine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N5-(1-iminobut-3-enyl)-L-ornithine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [733] | ||
N5-(1-iminobutyl)-L-ornithine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N5-(1-iminobutyl)-L-ornithine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N5-(1-iminobutyl)-L-ornithine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [733] | ||
N5-(1-iminopropyl)-L-ornithine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for N5-(1-iminopropyl)-L-ornithine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N5-(1-iminopropyl)-L-ornithine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [733] | ||
Nitroarginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Nitroarginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Nitroarginine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
Piperidin-(2E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Piperidin-(2E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Piperidin-(2E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [737] | ||
Pyrrolidin-(2Z)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Pyrrolidin-(2Z)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pyrrolidin-(2Z)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
S-(Dimethylarsenic)Cysteine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for S-(Dimethylarsenic)Cysteine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of S-(Dimethylarsenic)Cysteine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
S-Ethyl-N-Phenyl-Isothiourea [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for S-Ethyl-N-Phenyl-Isothiourea. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of S-Ethyl-N-Phenyl-Isothiourea through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [738] | ||
S-Isopropyl-Isothiourea [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for S-Isopropyl-Isothiourea. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of S-Isopropyl-Isothiourea through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
Se-Ethyl-Isoselenourea [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for Se-Ethyl-Isoselenourea. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Se-Ethyl-Isoselenourea through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [78], [592] | ||
THIOCITRULLINE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for THIOCITRULLINE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of THIOCITRULLINE through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [730] | ||
[1,3]Oxazinan-(2E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for [1,3]Oxazinan-(2E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [1,3]Oxazinan-(2E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [729] | ||
[1,3]Thiazinan-(2E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for [1,3]Thiazinan-(2E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [1,3]Thiazinan-(2E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [78], [592] | ||
[1,4]Oxazepan-(3E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for [1,4]Oxazepan-(3E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [1,4]Oxazepan-(3E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
[1,4]Thiazepan-(3E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for [1,4]Thiazepan-(3E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [1,4]Thiazepan-(3E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [723] | ||
[1,4]Thiazepan-(5E)-ylideneamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for [1,4]Thiazepan-(5E)-ylideneamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [1,4]Thiazepan-(5E)-ylideneamine through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [592], [737] | ||
L-NIL [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nitric oxide synthase endothelial (NOS3) is a therapeutic target for L-NIL. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-NIL through regulating the expression of Nitric oxide synthase endothelial (NOS3). | [148], [592] | ||
Notch-1 receptor (NOTCH1)
LY3039478 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Notch-1 receptor (NOTCH1) is a therapeutic target for LY3039478. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY3039478 through regulating the expression of Notch-1 receptor (NOTCH1). | [739], [740] | ||
OMP-52M51 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Notch-1 receptor (NOTCH1) is a therapeutic target for OMP-52M51. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OMP-52M51 through regulating the expression of Notch-1 receptor (NOTCH1). | [38], [739] | ||
Nuclear factor erythroid 2-related factor 2 (Nrf2)
ABT-RTA-408 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for ABT-RTA-408. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABT-RTA-408 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [438], [741] | ||
CXA10 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for CXA10. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CXA10 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [742] | ||
Omaveloxolone [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for Omaveloxolone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Omaveloxolone through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [743] | ||
OT-551 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for OT-551. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OT-551 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [116], [741] | ||
OT551 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for OT551. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OT551 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [744] | ||
SFX-01 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for SFX-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SFX-01 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [745] | ||
HPP971 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for HPP971. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HPP971 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [746] | ||
CAT4001 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for CAT4001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CAT4001 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [747] | ||
M102 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for M102. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of M102 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [748] | ||
TFM735 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nuclear factor erythroid 2-related factor 2 (Nrf2) is a therapeutic target for TFM735. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TFM735 through regulating the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2). | [741], [743] | ||
Nucleophosmin (NPM1)
IPP-204106 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Nucleophosmin (NPM1) is a therapeutic target for IPP-204106. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IPP-204106 through regulating the expression of Nucleophosmin (NPM1). | [379], [749] | ||
Oxalosuccinate decarboxylase (IDH1)
Ivosidenib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Oxalosuccinate decarboxylase (IDH1) is a therapeutic target for Ivosidenib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ivosidenib through regulating the expression of Oxalosuccinate decarboxylase (IDH1). | [750], [751] | ||
IDH305 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Oxalosuccinate decarboxylase (IDH1) is a therapeutic target for IDH305. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IDH305 through regulating the expression of Oxalosuccinate decarboxylase (IDH1). | [750], [752] | ||
LY3410738 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Oxalosuccinate decarboxylase (IDH1) is a therapeutic target for LY3410738. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY3410738 through regulating the expression of Oxalosuccinate decarboxylase (IDH1). | [750], [753] | ||
Peroxisome proliferator-activated receptor alpha (PPARA)
Bezafibrate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Bezafibrate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bezafibrate through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [755] | ||
Ciprofibrate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Ciprofibrate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ciprofibrate through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [756] | ||
Fenofibrate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Fenofibrate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Fenofibrate through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [757] | ||
Lobeglitazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Lobeglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lobeglitazone through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [758] | ||
Pemafibrate [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Pemafibrate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pemafibrate through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [755] | ||
BMS-298585 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for BMS-298585. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-298585 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [636], [754] | ||
CS-038 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for CS-038. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CS-038 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [759] | ||
GFT-505 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GFT-505. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GFT-505 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [760] | ||
Imiglitazar [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Imiglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Imiglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [761] | ||
Ragaglitazar [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Ragaglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ragaglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [762] | ||
TESAGLITAZAR [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for TESAGLITAZAR. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TESAGLITAZAR through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [763] | ||
ZYH-1 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for ZYH-1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZYH-1 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [764] | ||
GFT14 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GFT14. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GFT14 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [765] | ||
LY-518674 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for LY-518674. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY-518674 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [766] | ||
Naveglitazar [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Naveglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Naveglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [166], [754] | ||
ONO-5129 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for ONO-5129. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ONO-5129 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [767] | ||
ZYH7 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for ZYH7. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZYH7 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [768] | ||
AVE0897 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for AVE0897. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AVE0897 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [769] | ||
CDT-fenofibrate [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for CDT-fenofibrate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CDT-fenofibrate through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [770] | ||
GW-409544 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GW-409544. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-409544 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [771] | ||
Oxeglitazar [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Oxeglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Oxeglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [772] | ||
TPST-1120 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for TPST-1120. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TPST-1120 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [773] | ||
MC-3001 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for MC-3001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MC-3001 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [774] | ||
MC-3002 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for MC-3002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MC-3002 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [775] | ||
PIRINIXIC ACID [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for PIRINIXIC ACID. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PIRINIXIC ACID through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [776] | ||
Romazarit [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Romazarit. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Romazarit through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [166], [754] | ||
(9Z,12E)-12-nitrooctadeca-9,12-dienoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [777] | ||
(E)-12-Nitrooctadec-12-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for (E)-12-Nitrooctadec-12-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-12-Nitrooctadec-12-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [778] | ||
(E)-13-Nitrooctadec-12-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for (E)-13-Nitrooctadec-12-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-13-Nitrooctadec-12-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [778] | ||
(E)-4-(3,5-dimethoxystyryl)phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for (E)-4-(3,5-dimethoxystyryl)phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-4-(3,5-dimethoxystyryl)phenol through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [779] | ||
8S-HETE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for 8S-HETE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 8S-HETE through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [764] | ||
AD-5061 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for AD-5061. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AD-5061 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [780] | ||
BMS-687453 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for BMS-687453. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-687453 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [781] | ||
CP-775146 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for CP-775146. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CP-775146 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [148], [754] | ||
DB-900 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for DB-900. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DB-900 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [782] | ||
Deoxy-Bigchap [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Deoxy-Bigchap. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Deoxy-Bigchap through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [783] | ||
DRF 2519 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for DRF 2519. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DRF 2519 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [784] | ||
eicosatetranoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for eicosatetranoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of eicosatetranoic acid through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [785] | ||
Fibrates [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Fibrates. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Fibrates through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [786] | ||
GSK-9578 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GSK-9578. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-9578 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [778] | ||
GW-2331 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GW-2331. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-2331 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [787] | ||
GW7647 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GW7647. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW7647 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [788] | ||
L-165461 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for L-165461. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-165461 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [786] | ||
L-796449 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for L-796449. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-796449 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [755] | ||
LL-6531 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for LL-6531. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LL-6531 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [789] | ||
LY-465608 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for LY-465608. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY-465608 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [790] | ||
N-oleoylethanolamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for N-oleoylethanolamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of N-oleoylethanolamide through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [791] | ||
pristanic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for pristanic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of pristanic acid through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [792] | ||
reglitazar [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for reglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of reglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [793] | ||
TZD18 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for TZD18. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TZD18 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [794] | ||
ZY H2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for ZY H2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZY H2 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [795] | ||
Aleglitazar [Discontinued in Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Aleglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Aleglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [796] | ||
AR-H049020 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for AR-H049020. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AR-H049020 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [792] | ||
AVE-0847 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for AVE-0847. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AVE-0847 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [797] | ||
AVE-8134 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for AVE-8134. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AVE-8134 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [798] | ||
BM-17.0744 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for BM-17.0744. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BM-17.0744 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [166], [754] | ||
BVT-142 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for BVT-142. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BVT-142 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [799] | ||
CS-204 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for CS-204. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CS-204 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [800] | ||
CS-207 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for CS-207. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CS-207 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [801] | ||
DRF 10945 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for DRF 10945. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DRF 10945 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [802] | ||
E-3030 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for E-3030. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of E-3030 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [803] | ||
GSK-677954 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for GSK-677954. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-677954 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [804] | ||
Indeglitazar [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Indeglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Indeglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [31], [754] | ||
KRP-101 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for KRP-101. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KRP-101 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [805] | ||
KRP-105 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for KRP-105. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KRP-105 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [763] | ||
KRP-297 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for KRP-297. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KRP-297 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [792] | ||
LG-101280 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for LG-101280. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LG-101280 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [806] | ||
LY-929 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for LY-929. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY-929 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [807] | ||
MP-136 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for MP-136. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MP-136 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [808] | ||
NS-220 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for NS-220. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NS-220 through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [809] | ||
Reglixane [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Reglixane. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Reglixane through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [810] | ||
Sipoglitazar [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Sipoglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sipoglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [811] | ||
Sodelglitazar [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor alpha (PPARA) is a therapeutic target for Sodelglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sodelglitazar through regulating the expression of Peroxisome proliferator-activated receptor alpha (PPARA). | [754], [812] | ||
Peroxisome proliferator-activated receptor gamma (PPAR-gamma)
Glitazone [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Glitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Glitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [756], [813] | ||
Lobeglitazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Lobeglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Lobeglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [814] | ||
Pioglitazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Pioglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pioglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [390], [813] | ||
Rosiglitazone XR [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Rosiglitazone XR. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rosiglitazone XR through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [815] | ||
Thiazolidinedione [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Thiazolidinedione. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Thiazolidinedione through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [755], [813] | ||
Troglitazone [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Troglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Troglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [814] | ||
Bardoxolone methyl [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Bardoxolone methyl. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bardoxolone methyl through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [816] | ||
BMS-298585 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for BMS-298585. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-298585 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [636], [813] | ||
CS-038 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CS-038. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CS-038 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [759], [813] | ||
DRF-2593 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for DRF-2593. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DRF-2593 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [762], [813] | ||
FARGLITAZAR [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for FARGLITAZAR. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FARGLITAZAR through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [763], [813] | ||
Imiglitazar [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Imiglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Imiglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [761], [813] | ||
MBX-102 [Phase 2/3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for MBX-102. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MBX-102 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [390], [813] | ||
Ragaglitazar [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Ragaglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ragaglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [817] | ||
Rivoglitazone [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Rivoglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rivoglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [760], [813] | ||
TESAGLITAZAR [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for TESAGLITAZAR. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TESAGLITAZAR through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [818] | ||
ZYH-1 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ZYH-1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZYH-1 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [764], [813] | ||
CHS-131 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CHS-131. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHS-131 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [819] | ||
FK-614 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for FK-614. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FK-614 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [820] | ||
GED-0507-34-Levo [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GED-0507-34-Levo. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GED-0507-34-Levo through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [821] | ||
MBX-2044 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for MBX-2044. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MBX-2044 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [822] | ||
Naveglitazar [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Naveglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Naveglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [166], [813] | ||
Netoglitazone [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Netoglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Netoglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [765], [813] | ||
OMS405 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for OMS405. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OMS405 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [823] | ||
ONO-5129 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ONO-5129. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ONO-5129 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [114], [813] | ||
T3D-959 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for T3D-959. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of T3D-959 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [819] | ||
CLX-0921 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CLX-0921. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CLX-0921 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [824] | ||
DSP-8658 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for DSP-8658. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DSP-8658 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [770], [813] | ||
Englitazone sodium [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Englitazone sodium. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Englitazone sodium through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [825] | ||
GW-409544 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GW-409544. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-409544 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [826] | ||
Oxeglitazar [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Oxeglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Oxeglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [772], [813] | ||
ADD-3878 [Discontinued]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ADD-3878. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ADD-3878 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [166], [813] | ||
MC-3002 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for MC-3002. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MC-3002 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [806], [813] | ||
(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
(9Z,12E)-12-nitrooctadeca-9,12-dienoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-10-Nitrohexadec-9-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-10-Nitrohexadec-9-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-10-Nitrohexadec-9-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-10-nitrooctadec-9-enoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-10-nitrooctadec-9-enoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-10-nitrooctadec-9-enoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-12-Nitrooctadec-12-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-12-Nitrooctadec-12-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-12-Nitrooctadec-12-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-13-Nitrooctadec-12-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-13-Nitrooctadec-12-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-13-Nitrooctadec-12-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-5-Nitrooctadec-5-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-5-Nitrooctadec-5-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-5-Nitrooctadec-5-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-6-Nitrooctadec-5-enoic Acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-6-Nitrooctadec-5-enoic Acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-6-Nitrooctadec-5-enoic Acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [376], [813] | ||
(E)-9-Nitrohexadec-9-enoicAcid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-9-Nitrohexadec-9-enoicAcid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-9-Nitrohexadec-9-enoicAcid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
(E)-9-nitrooctadec-9-enoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for (E)-9-nitrooctadec-9-enoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (E)-9-nitrooctadec-9-enoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
15-deoxy-Delta(12, 14)-prostaglandin J(2) [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for 15-deoxy-Delta(12, 14)-prostaglandin J(2). The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 15-deoxy-Delta(12, 14)-prostaglandin J(2) through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
2-chloro-5-nitro-N-phenylbenzamide [Investigative]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for 2-chloro-5-nitro-N-phenylbenzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-chloro-5-nitro-N-phenylbenzamide through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [778], [813] | ||
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for 2-chloro-5-nitro-N-phenylbenzamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-chloro-5-nitro-N-phenylbenzamide through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [827] | |||
3-(5-methoxy-1H-indol-3-yl)propanoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for 3-(5-methoxy-1H-indol-3-yl)propanoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(5-methoxy-1H-indol-3-yl)propanoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
9-hydroxyoctadecadienoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for 9-hydroxyoctadecadienoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 9-hydroxyoctadecadienoic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [78], [813] | ||
AD-5061 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for AD-5061. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AD-5061 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [828] | ||
BADGE [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for BADGE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BADGE through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [829] | ||
BRL-48482 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for BRL-48482. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BRL-48482 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [830] | ||
CHLOROCYCLINONE A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CHLOROCYCLINONE A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHLOROCYCLINONE A through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [830] | ||
CHLOROCYCLINONE B [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CHLOROCYCLINONE B. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHLOROCYCLINONE B through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
CHLOROCYCLINONE C [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CHLOROCYCLINONE C. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHLOROCYCLINONE C through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [830] | ||
CHLOROCYCLINONE D [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CHLOROCYCLINONE D. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CHLOROCYCLINONE D through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [830] | ||
COOH [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for COOH. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of COOH through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [832] | ||
DB-900 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for DB-900. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DB-900 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [833] | ||
DRF 2519 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for DRF 2519. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DRF 2519 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [834] | ||
GNF-PF-2893 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GNF-PF-2893. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GNF-PF-2893 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [835] | ||
GNF-PF-3037 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GNF-PF-3037. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GNF-PF-3037 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [376], [813] | ||
GW-2331 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GW-2331. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW-2331 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [787], [813] | ||
GW0072 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GW0072. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW0072 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [836] | ||
GW1929 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GW1929. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW1929 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [837] | ||
GW7845 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GW7845. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GW7845 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [781], [813] | ||
ISIS 105987 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ISIS 105987. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 105987 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [838] | ||
ISIS 105989 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ISIS 105989. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 105989 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [839] | ||
ISIS 105990 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ISIS 105990. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 105990 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [838] | ||
ISIS 106008 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ISIS 106008. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 106008 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [838] | ||
L-165461 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-165461. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-165461 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [786], [813] | ||
L-764406 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-764406. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-764406 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [840] | ||
L-783483 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-783483. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-783483 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [841] | ||
L-796449 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-796449. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-796449 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [842] | ||
L-Tryptophan-L-2-aminoadipic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-Tryptophan-L-2-aminoadipic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Tryptophan-L-2-aminoadipic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
L-Tryptophan-L-arginine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-Tryptophan-L-arginine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Tryptophan-L-arginine through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
L-Tryptophan-L-asparagine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-Tryptophan-L-asparagine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Tryptophan-L-asparagine through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
L-Tryptophan-L-aspartic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-Tryptophan-L-aspartic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Tryptophan-L-aspartic acid through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
L-Tryptophan-L-glutamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-Tryptophan-L-glutamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Tryptophan-L-glutamine through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
L-Tryptophan-L-leucine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for L-Tryptophan-L-leucine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of L-Tryptophan-L-leucine through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
LG100754 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for LG100754. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LG100754 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [791], [813] | ||
LY-465608 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for LY-465608. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY-465608 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [779], [813] | ||
nTzDpa [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for nTzDpa. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of nTzDpa through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [843] | ||
PAT5A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for PAT5A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PAT5A through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [844] | ||
PD-068235 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for PD-068235. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-068235 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [831] | ||
Ploglitazone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Ploglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ploglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [786], [813] | ||
reglitazar [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for reglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of reglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [764], [813] | ||
SB-213068 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for SB-213068. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SB-213068 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [842] | ||
T0070907 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for T0070907. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of T0070907 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [844] | ||
tagitinin A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for tagitinin A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of tagitinin A through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [845] | ||
tirotundin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for tirotundin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of tirotundin through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [846] | ||
TZD18 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for TZD18. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TZD18 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [794], [813] | ||
ZY H2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for ZY H2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ZY H2 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [795], [813] | ||
[125I]SB-236636 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for [125I]SB-236636. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [125I]SB-236636 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [847] | ||
[3H]GW2331 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for [3H]GW2331. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of [3H]GW2331 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [848] | ||
AD-5075 [Terminated]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for AD-5075. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AD-5075 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [763], [813] | ||
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for AD-5075. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AD-5075 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [849] | |||
AKP-320 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for AKP-320. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AKP-320 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [782], [813] | ||
AVE-0847 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for AVE-0847. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AVE-0847 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [797], [813] | ||
BVT-142 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for BVT-142. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BVT-142 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [850] | ||
CS-204 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for CS-204. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CS-204 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [851] | ||
DARGLITAZONE [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for DARGLITAZONE. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DARGLITAZONE through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [852] | ||
DS-6930 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for DS-6930. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DS-6930 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [808], [813] | ||
E-3030 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for E-3030. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of E-3030 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [853] | ||
Edaglitazone [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Edaglitazone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Edaglitazone through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [854] | ||
GSK-677954 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for GSK-677954. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GSK-677954 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [166], [813] | ||
Indeglitazar [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Indeglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Indeglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [855] | ||
KRP-297 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for KRP-297. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KRP-297 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [815] | ||
LY-929 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for LY-929. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY-929 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [856] | ||
Reglixane [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Reglixane. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Reglixane through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [810], [813] | ||
SB-219994 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for SB-219994. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SB-219994 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [813], [835] | ||
Sipoglitazar [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Sipoglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sipoglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [811], [813] | ||
Sodelglitazar [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for Sodelglitazar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Sodelglitazar through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [812], [813] | ||
YM-440 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a therapeutic target for YM-440. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of YM-440 through regulating the expression of Peroxisome proliferator-activated receptor gamma (PPAR-gamma). | [803], [813] | ||
Platelet-derived growth factor receptor beta (PDGFRB)
Becaplermin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Becaplermin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Becaplermin through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [857] | ||
Romiplostim [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Romiplostim. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Romiplostim through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [233], [379] | ||
E-3810 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for E-3810. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of E-3810 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [858] | ||
Famitinib [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Famitinib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Famitinib through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [859] | ||
MK-2461 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for MK-2461. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-2461 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [860] | ||
SNN-0031 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for SNN-0031. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SNN-0031 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [861] | ||
XL-820 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for XL-820. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of XL-820 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [862] | ||
TAK-593 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for TAK-593. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAK-593 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [863] | ||
(1H-indol-2-yl)(5-methoxy-1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (1H-indol-2-yl)(5-methoxy-1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (1H-indol-2-yl)(5-methoxy-1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
(1H-indol-2-yl)(5-phenoxy-1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (1H-indol-2-yl)(5-phenoxy-1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (1H-indol-2-yl)(5-phenoxy-1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
(1H-indol-2-yl)(6-methoxy-1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (1H-indol-2-yl)(6-methoxy-1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (1H-indol-2-yl)(6-methoxy-1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
(2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [865] | ||
(5-fluoro-1H-indol-2-yl)-(1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (5-fluoro-1H-indol-2-yl)-(1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (5-fluoro-1H-indol-2-yl)-(1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
(5-hydroxy-1H-indol-2-yl)(1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (5-hydroxy-1H-indol-2-yl)(1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (5-hydroxy-1H-indol-2-yl)(1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
(benzo[b]furan-2-yl)-(1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for (benzo[b]furan-2-yl)-(1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (benzo[b]furan-2-yl)-(1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
1-Phenyl-1H-benzoimidazol-5-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 1-Phenyl-1H-benzoimidazol-5-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Phenyl-1H-benzoimidazol-5-ol through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [867] | ||
1-Phenyl-1H-benzoimidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 1-Phenyl-1H-benzoimidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 1-Phenyl-1H-benzoimidazole through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [699] | ||
2-(1H-indazol-3-yl)-1H-benzo[d]imidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 2-(1H-indazol-3-yl)-1H-benzo[d]imidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(1H-indazol-3-yl)-1H-benzo[d]imidazole through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [868] | ||
3-((E)-Styryl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-((E)-Styryl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-((E)-Styryl)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
3-(1H-Indol-3-yl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(1H-Indol-3-yl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(1H-Indol-3-yl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(1H-Indol-3-yl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(1H-Indol-3-yl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(1H-Indol-3-yl)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(2-Cyclohexyl-ethyl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(2-Cyclohexyl-ethyl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(2-Cyclohexyl-ethyl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
3-(3,4-Dichloro-phenyl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(3,4-Dichloro-phenyl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(3,4-Dichloro-phenyl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(3,4-Difluoro-phenyl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(3,4-Difluoro-phenyl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(3,4-Difluoro-phenyl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(4-dimethylamino-benzylidenyl)-2-indolinone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(4-dimethylamino-benzylidenyl)-2-indolinone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-dimethylamino-benzylidenyl)-2-indolinone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [871] | ||
3-(4-Fluoro-phenyl)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(4-Fluoro-phenyl)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(4-Fluoro-phenyl)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
3-Benzyloxy-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Benzyloxy-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Benzyloxy-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-Cyclohexylethynyl-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Cyclohexylethynyl-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Cyclohexylethynyl-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-Cyclopent-1-enyl-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Cyclopent-1-enyl-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Cyclopent-1-enyl-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
3-Cyclopentyl-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Cyclopentyl-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Cyclopentyl-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-Pyridin-3-yl-quinoline-6,7-diol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Pyridin-3-yl-quinoline-6,7-diol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Pyridin-3-yl-quinoline-6,7-diol through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-Pyridin-4-yl-quinolin-7-ol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Pyridin-4-yl-quinolin-7-ol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Pyridin-4-yl-quinolin-7-ol through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
3-Pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
3-Pyridin-4-yl-quinoline-5,7-diol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Pyridin-4-yl-quinoline-5,7-diol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Pyridin-4-yl-quinoline-5,7-diol through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
3-Thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 3-Thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-Thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [873] | ||
4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(3-Ethoxy-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3-Ethoxy-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3-Ethoxy-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(5-Methoxy-benzoimidazol-1-yl)-phenylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(5-Methoxy-benzoimidazol-1-yl)-phenylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(5-Methoxy-benzoimidazol-1-yl)-phenylamine through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
4-(6,7-Dimethoxy-quinolin-3-yl)-benzoic acid [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(6,7-Dimethoxy-quinolin-3-yl)-benzoic acid. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(6,7-Dimethoxy-quinolin-3-yl)-benzoic acid through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
4-(6,7-Dimethoxy-quinolin-3-yl)-phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-(6,7-Dimethoxy-quinolin-3-yl)-phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(6,7-Dimethoxy-quinolin-3-yl)-phenol through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
4-Benzoimidazol-1-yl-phenylamine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 4-Benzoimidazol-1-yl-phenylamine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-Benzoimidazol-1-yl-phenylamine through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [871] | ||
5,6,7-Trimethoxy-3-pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 5,6,7-Trimethoxy-3-pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,6,7-Trimethoxy-3-pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
5,7-Dimethoxy-3-pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 5,7-Dimethoxy-3-pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dimethoxy-3-pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
5,7-Dimethoxy-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 5,7-Dimethoxy-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dimethoxy-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
5,7-Dimethyl-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 5,7-Dimethyl-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5,7-Dimethyl-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
5-(6,7-Dimethoxy-quinolin-3-yl)-1H-pyridin-2-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 5-(6,7-Dimethoxy-quinolin-3-yl)-1H-pyridin-2-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-(6,7-Dimethoxy-quinolin-3-yl)-1H-pyridin-2-one through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
5-Methoxy-1-phenyl-1H-benzoimidazole [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 5-Methoxy-1-phenyl-1H-benzoimidazole. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 5-Methoxy-1-phenyl-1H-benzoimidazole through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [871] | ||
6,7-Dichloro-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dichloro-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dichloro-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Difluoro-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Difluoro-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Difluoro-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-((E)-styryl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-((E)-styryl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-((E)-styryl)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-(3-methoxy-phenyl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-(3-methoxy-phenyl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-(3-methoxy-phenyl)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-(4-methoxy-phenyl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-(4-methoxy-phenyl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-(4-methoxy-phenyl)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-(4-nitro-phenyl)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-(4-nitro-phenyl)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-(4-nitro-phenyl)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
6,7-Dimethoxy-3-p-tolyl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-p-tolyl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-p-tolyl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-phenyl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-phenyl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-phenyl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-phenylethynyl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-phenylethynyl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-phenylethynyl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-pyridin-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-pyridin-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-pyridin-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-3-pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
6,7-Dimethoxy-3-thiophen-2-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-3-thiophen-2-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-3-thiophen-2-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
6,7-Dimethoxy-4-m-tolyloxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-4-m-tolyloxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-4-m-tolyloxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
6,7-Dimethoxy-4-phenoxy-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6,7-Dimethoxy-4-phenoxy-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6,7-Dimethoxy-4-phenoxy-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
6-Methoxy-3-pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6-Methoxy-3-pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Methoxy-3-pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
6-Methoxy-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 6-Methoxy-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 6-Methoxy-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
7-Chloro-3-pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 7-Chloro-3-pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Chloro-3-pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [869] | ||
7-Fluoro-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 7-Fluoro-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Fluoro-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
7-Methoxy-3-pyridin-4-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 7-Methoxy-3-pyridin-4-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Methoxy-3-pyridin-4-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
7-Methoxy-3-thiophen-3-yl-quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 7-Methoxy-3-thiophen-3-yl-quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Methoxy-3-thiophen-3-yl-quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
7-Thiophen-3-yl-[1,3]dioxolo[4,5-g]quinoline [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for 7-Thiophen-3-yl-[1,3]dioxolo[4,5-g]quinoline. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 7-Thiophen-3-yl-[1,3]dioxolo[4,5-g]quinoline through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
AGL 2043 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for AGL 2043. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AGL 2043 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [749] | ||
Benzyl-(6,7-dimethoxy-quinolin-3-yl)-amine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Benzyl-(6,7-dimethoxy-quinolin-3-yl)-amine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Benzyl-(6,7-dimethoxy-quinolin-3-yl)-amine through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
Bis(5-acetoxybenzo[b]furan-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis(5-acetoxybenzo[b]furan-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(5-acetoxybenzo[b]furan-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
Bis(5-aminobenzo[b]furan-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis(5-aminobenzo[b]furan-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(5-aminobenzo[b]furan-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
Bis(5-hydroxybenzo[b]furan-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis(5-hydroxybenzo[b]furan-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(5-hydroxybenzo[b]furan-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [874] | ||
Bis(5-methoxybenzo[b]furan-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis(5-methoxybenzo[b]furan-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(5-methoxybenzo[b]furan-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [871] | ||
Bis(6-hydroxybenzo[b]furan-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis(6-hydroxybenzo[b]furan-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(6-hydroxybenzo[b]furan-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
Bis(benzo[b]furan-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis(benzo[b]furan-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis(benzo[b]furan-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
Bis-(5-hydroxy-1H-indol-2-yl)-methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Bis-(5-hydroxy-1H-indol-2-yl)-methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bis-(5-hydroxy-1H-indol-2-yl)-methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [875] | ||
BMS 536924 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for BMS 536924. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS 536924 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [865] | ||
CP-673451 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for CP-673451. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CP-673451 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [876] | ||
Di(1H-indol-2-yl)methanone [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Di(1H-indol-2-yl)methanone. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Di(1H-indol-2-yl)methanone through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [877] | ||
GTP-14564 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for GTP-14564. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GTP-14564 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [878] | ||
HKI-9924129 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for HKI-9924129. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HKI-9924129 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [879] | ||
JNJ-10198409 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for JNJ-10198409. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of JNJ-10198409 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [858] | ||
Ki-11502 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Ki-11502. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ki-11502 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
Ki-20227 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Ki-20227. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ki-20227 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [880] | ||
PD-0166326 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PD-0166326. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0166326 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
PD-0173952 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PD-0173952. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0173952 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
PD-0173955 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PD-0173955. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0173955 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [864] | ||
PD-0173956 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PD-0173956. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0173956 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
PD-0173958 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PD-0173958. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0173958 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
PD-0179483 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PD-0179483. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-0179483 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
PDGF receptor tyrosine kinase inhibitor III [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for PDGF receptor tyrosine kinase inhibitor III. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PDGF receptor tyrosine kinase inhibitor III through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [882] | ||
Ro-4396686 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for Ro-4396686. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro-4396686 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
RPR-101511 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for RPR-101511. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RPR-101511 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
RPR-108514A [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for RPR-108514A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RPR-108514A through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [870] | ||
SU-11652 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for SU-11652. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SU-11652 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [872] | ||
TG-100435 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for TG-100435. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TG-100435 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [881] | ||
XB-387 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for XB-387. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of XB-387 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [883] | ||
AG1295 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for AG1295. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AG1295 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [884] | ||
CDP-860 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for CDP-860. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CDP-860 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [885] | ||
CEP-2563 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for CEP-2563. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CEP-2563 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [699] | ||
RG-13022 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for RG-13022. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RG-13022 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [866] | ||
SRI-62-834 [Discontinued in Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Platelet-derived growth factor receptor beta (PDGFRB) is a therapeutic target for SRI-62-834. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SRI-62-834 through regulating the expression of Platelet-derived growth factor receptor beta (PDGFRB). | [379], [886] | ||
Programmed cell death 1 ligand 1 (PD-L1)
Atezolizumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Atezolizumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Atezolizumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [887] | ||
Avelumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Avelumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Avelumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [233], [373] | ||
Bavencio [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Bavencio. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bavencio through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [888] | ||
Durvalumab [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Durvalumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Durvalumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [889] | ||
RG-7446 [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for RG-7446. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RG-7446 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [890] | ||
CS1001 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CS1001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CS1001 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [891] | ||
KN046 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for KN046. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KN046 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [892] | ||
MEDI4736 [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MEDI4736. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MEDI4736 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [893] | ||
MPDL-3280A [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MPDL-3280A. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MPDL-3280A through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [894] | ||
BGB-A333 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for BGB-A333. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BGB-A333 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [895] | ||
Bintrafusp alfa [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Bintrafusp alfa. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Bintrafusp alfa through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [896] | ||
CX-072 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CX-072. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CX-072 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [897] | ||
GS-4224 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for GS-4224. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GS-4224 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [898] | ||
INCB86550 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for INCB86550. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INCB86550 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [899] | ||
KN035 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for KN035. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KN035 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [900] | ||
M7824 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for M7824. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of M7824 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [118], [373] | ||
NM21-1480 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for NM21-1480. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NM21-1480 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [889] | ||
Pidilizumab [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Pidilizumab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Pidilizumab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [38], [373] | ||
ALPN-202 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for ALPN-202. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ALPN-202 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [901] | ||
Anti-PD-L1 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Anti-PD-L1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Anti-PD-L1 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [902] | ||
Anti-PD-L1 CSR T cells [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Anti-PD-L1 CSR T cells. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Anti-PD-L1 CSR T cells through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [38], [373] | ||
BMS-986189 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for BMS-986189. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS-986189 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [889] | ||
CA-170 [Phase 1]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CA-170. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CA-170 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [118], [373] | ||
Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CA-170. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CA-170 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [903] | |||
Cosibelimab [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for Cosibelimab. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Cosibelimab through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [904] | ||
FAZ053 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for FAZ053. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FAZ053 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [889] | ||
FS118 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for FS118. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of FS118 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [905] | ||
GEN1046 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for GEN1046. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GEN1046 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [906] | ||
IBI318 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for IBI318. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IBI318 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [907] | ||
INBRX-105 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for INBRX-105. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INBRX-105 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [908] | ||
KD033 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for KD033. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of KD033 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [909] | ||
LY3300054 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for LY3300054. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY3300054 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [38], [373] | ||
LY3415244 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for LY3415244. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY3415244 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [910] | ||
MCLA-145 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MCLA-145. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MCLA-145 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [911] | ||
MSB2311 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for MSB2311. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MSB2311 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [889] | ||
PD-L1 t-haNK [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for PD-L1 t-haNK. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PD-L1 t-haNK through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [912] | ||
RG6084 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for RG6084. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RG6084 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [118], [373] | ||
TAK-252 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for TAK-252. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAK-252 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [913] | ||
CA-327 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Programmed cell death 1 ligand 1 (PD-L1) is a therapeutic target for CA-327. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CA-327 through regulating the expression of Programmed cell death 1 ligand 1 (PD-L1). | [373], [889] | ||
Proto-oncogene c-Myc (MYC)
AVI-5126 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Proto-oncogene c-Myc (MYC) is a therapeutic target for AVI-5126. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AVI-5126 through regulating the expression of Proto-oncogene c-Myc (MYC). | [373], [914] | ||
Resten-NG [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Proto-oncogene c-Myc (MYC) is a therapeutic target for Resten-NG. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Resten-NG through regulating the expression of Proto-oncogene c-Myc (MYC). | [373], [915] | ||
TWS-119 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Proto-oncogene c-Myc (MYC) is a therapeutic target for TWS-119. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TWS-119 through regulating the expression of Proto-oncogene c-Myc (MYC). | [119], [373] | ||
Pyruvate dehydrogenase kinase 1 (PDHK1)
Dichloroacetate [Phase 4]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Pyruvate dehydrogenase kinase 1 (PDHK1) is a therapeutic target for Dichloroacetate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Dichloroacetate through regulating the expression of Pyruvate dehydrogenase kinase 1 (PDHK1). | [916], [917] | ||
Pyruvate kinase M2 (PKM)
CAP-232 [Phase 2a]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Pyruvate kinase M2 (PKM) is a therapeutic target for CAP-232. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CAP-232 through regulating the expression of Pyruvate kinase M2 (PKM). | [485], [918] | ||
TP-1454 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Pyruvate kinase M2 (PKM) is a therapeutic target for TP-1454. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TP-1454 through regulating the expression of Pyruvate kinase M2 (PKM). | [166], [918] | ||
Retinoic acid receptor alpha (RARA)
Tamibarotene [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for Tamibarotene. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Tamibarotene through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [920] | ||
IRX-5183 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for IRX-5183. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IRX-5183 through regulating the expression of Retinoic acid receptor alpha (RARA). | [38], [919] | ||
SY-1425 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for SY-1425. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SY-1425 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [921] | ||
AGN193109 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for AGN193109. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AGN193109 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [922] | ||
AGN193836 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for AGN193836. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AGN193836 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [923] | ||
BMS614 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for BMS614. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS614 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [924] | ||
BMS753 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for BMS753. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BMS753 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [925] | ||
CD666 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for CD666. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CD666 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [926] | ||
Ro 40-6055 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for Ro 40-6055. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro 40-6055 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [927] | ||
Ro 41-5253 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for Ro 41-5253. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro 41-5253 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [928] | ||
Ro-40-0655 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for Ro-40-0655. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ro-40-0655 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [929] | ||
LG100268 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Retinoic acid receptor alpha (RARA) is a therapeutic target for LG100268. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LG100268 through regulating the expression of Retinoic acid receptor alpha (RARA). | [919], [930] | ||
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)
Gallopamil [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) is a therapeutic target for Gallopamil. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Gallopamil through regulating the expression of Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2). | [931], [932] | ||
Mydicar [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) is a therapeutic target for Mydicar. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Mydicar through regulating the expression of Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2). | [931], [933] | ||
Sequestosome-1 p62 (SQSTM1)
IMX-942 [Preclinical]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Sequestosome-1 p62 (SQSTM1) is a therapeutic target for IMX-942. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IMX-942 through regulating the expression of Sequestosome-1 p62 (SQSTM1). | [934], [935] | ||
Serine/threonine-protein kinase mTOR (mTOR)
Glasdegib [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Glasdegib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Glasdegib through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [937] | ||
Novolimus [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Novolimus. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Novolimus through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [522], [936] | ||
Temsirolimus [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Temsirolimus. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Temsirolimus through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [938] | ||
Zotarolimus [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Zotarolimus. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Zotarolimus through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
Ridaforolimus [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Ridaforolimus. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ridaforolimus through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [939] | ||
ABI-009 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for ABI-009. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ABI-009 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [940] | ||
AZD-2014 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for AZD-2014. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD-2014 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
BEZ235 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for BEZ235. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BEZ235 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [38], [936] | ||
BGT226 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for BGT226. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BGT226 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
CC-223 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for CC-223. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CC-223 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [941] | ||
INK128 [Phase 2]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for INK128. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INK128 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [942] | ||
Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for INK128. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INK128 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [962] | |||
LY3023414 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for LY3023414. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LY3023414 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [943] | ||
ME-344 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for ME-344. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ME-344 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [944] | ||
MM-141 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for MM-141. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MM-141 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [38], [936] | ||
OSI-027 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for OSI-027. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OSI-027 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [945] | ||
PF-04691502 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PF-04691502. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-04691502 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [946] | ||
PF-05212384 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PF-05212384. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-05212384 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [947] | ||
PQR309 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PQR309. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PQR309 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [948] | ||
Salirasib [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Salirasib. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Salirasib through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
SAR245409 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for SAR245409. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SAR245409 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [949] | ||
SF1126 [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for SF1126. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SF1126 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [38], [936] | ||
BI 860585 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for BI 860585. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of BI 860585 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [950] | ||
DS-3078 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for DS-3078. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DS-3078 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [951] | ||
DS-7423 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for DS-7423. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DS-7423 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [952] | ||
GDC-0349 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for GDC-0349. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GDC-0349 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
LAM-001 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for LAM-001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LAM-001 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [953] | ||
PWT-33597 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PWT-33597. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PWT-33597 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [954] | ||
VS-5584 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for VS-5584. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of VS-5584 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [955] | ||
(4-(6-morpholino-9H-purin-2-yl)phenyl)methanol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for (4-(6-morpholino-9H-purin-2-yl)phenyl)methanol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of (4-(6-morpholino-9H-purin-2-yl)phenyl)methanol through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [957] | ||
2-(6-morpholino-9H-purin-2-yl)phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 2-(6-morpholino-9H-purin-2-yl)phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-(6-morpholino-9H-purin-2-yl)phenol through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
2-chloro-N-(6-cyanopyridin-3-yl)propanamide [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 2-chloro-N-(6-cyanopyridin-3-yl)propanamide. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-chloro-N-(6-cyanopyridin-3-yl)propanamide through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [958] | ||
2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [959] | ||
3-(6-morpholino-9H-purin-2-yl)phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 3-(6-morpholino-9H-purin-2-yl)phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 3-(6-morpholino-9H-purin-2-yl)phenol through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
4-(2-(1H-indol-6-yl)-9H-purin-6-yl)morpholine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 4-(2-(1H-indol-6-yl)-9H-purin-6-yl)morpholine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2-(1H-indol-6-yl)-9H-purin-6-yl)morpholine through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
4-(2-(thiophen-2-yl)-9H-purin-6-yl)morpholine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 4-(2-(thiophen-2-yl)-9H-purin-6-yl)morpholine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2-(thiophen-2-yl)-9H-purin-6-yl)morpholine through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [960] | ||
4-(2-(thiophen-3-yl)-9H-purin-6-yl)morpholine [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 4-(2-(thiophen-3-yl)-9H-purin-6-yl)morpholine. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(2-(thiophen-3-yl)-9H-purin-6-yl)morpholine through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
4-(6-morpholino-9H-purin-2-yl)phenol [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for 4-(6-morpholino-9H-purin-2-yl)phenol. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of 4-(6-morpholino-9H-purin-2-yl)phenol through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
AP-21967 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for AP-21967. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AP-21967 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [957] | ||
AR-mTOR-26 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for AR-mTOR-26. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AR-mTOR-26 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
C-16-(S)-3-methylindolerapamycin [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for C-16-(S)-3-methylindolerapamycin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C-16-(S)-3-methylindolerapamycin through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [956] | ||
CU-906 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for CU-906. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of CU-906 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
EC-0565 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for EC-0565. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of EC-0565 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
EC-0845 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for EC-0845. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of EC-0845 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
EM-101 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for EM-101. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of EM-101 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [961] | ||
Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [959] | ||
HM-5016699 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for HM-5016699. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of HM-5016699 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
OXA-01 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for OXA-01. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OXA-01 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
P-2281 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for P-2281. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of P-2281 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
P-6915 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for P-6915. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of P-6915 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
PF-03772304 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PF-03772304. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-03772304 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
PF-05094037 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PF-05094037. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-05094037 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [963] | ||
PP-242 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PP-242. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PP-242 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [964] | ||
PP121 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for PP121. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PP121 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [965] | ||
Rapamycin complexed with immunophilin FKBP12 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Rapamycin complexed with immunophilin FKBP12. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Rapamycin complexed with immunophilin FKBP12 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [959] | ||
SB-2280 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for SB-2280. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SB-2280 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
SX-MTR1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for SX-MTR1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SX-MTR1 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
torin 1 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for torin 1. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of torin 1 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [965] | ||
Torin2 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for Torin2. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Torin2 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [966] | ||
X-387 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for X-387. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of X-387 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [381], [936] | ||
AZD8055 [Discontinued in Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for AZD8055. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of AZD8055 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [967] | ||
SCR-44001 [Terminated]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for SCR-44001. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SCR-44001 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [936], [968] | ||
TAFA-93 [Discontinued in Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine/threonine-protein kinase mTOR (mTOR) is a therapeutic target for TAFA-93. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAFA-93 through regulating the expression of Serine/threonine-protein kinase mTOR (mTOR). | [405], [936] | ||
Signal transducer and activator of transcription 3 (STAT3)
Acitretin [Approved]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for Acitretin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Acitretin through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [969] | ||
Napabucasin [Phase 3]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for Napabucasin. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Napabucasin through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [970] | ||
Atiprimod [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for Atiprimod. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Atiprimod through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [971] | ||
GLG-801 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for GLG-801. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GLG-801 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [933] | ||
Golotimod [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for Golotimod. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Golotimod through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [38], [608] | ||
IMX-110 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for IMX-110. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of IMX-110 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [38], [608] | ||
ISIS-STAT3 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS-STAT3. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS-STAT3 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [972] | ||
NT219 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for NT219. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of NT219 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [973] | ||
OPB-31121 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for OPB-31121. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OPB-31121 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [38], [608] | ||
WP-1066 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for WP-1066. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of WP-1066 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [38], [608] | ||
C188-9 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for C188-9. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of C188-9 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [974] | ||
DSP-0337 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for DSP-0337. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of DSP-0337 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [28], [608] | ||
OPB-111077 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for OPB-111077. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OPB-111077 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [975] | ||
OPB-51602 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for OPB-51602. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of OPB-51602 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [976] | ||
TAK-114 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for TAK-114. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of TAK-114 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [977] | ||
WP1220 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for WP1220. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of WP1220 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [978] | ||
GNF-PF-1399 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for GNF-PF-1399. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of GNF-PF-1399 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [979] | ||
ISIS 113176 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS 113176. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113176 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [972] | ||
ISIS 113187 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS 113187. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113187 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [972] | ||
ISIS 113209 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS 113209. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113209 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [972] | ||
ISIS 113210 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS 113210. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 113210 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [38], [608] | ||
ISIS 17148 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS 17148. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 17148 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [972] | ||
ISIS 17152 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Signal transducer and activator of transcription 3 (STAT3) is a therapeutic target for ISIS 17152. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 17152 through regulating the expression of Signal transducer and activator of transcription 3 (STAT3). | [608], [972] | ||
SRSF protein kinase 2 (SRPK2)
URMC-099 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | SRSF protein kinase 2 (SRPK2) is a therapeutic target for URMC-099. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of URMC-099 through regulating the expression of SRSF protein kinase 2 (SRPK2). | [531], [980] | ||
Superoxide dismutase Mn (SOD Mn)
Imisopasem manganese [Phase 2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Superoxide dismutase Mn (SOD Mn) is a therapeutic target for Imisopasem manganese. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Imisopasem manganese through regulating the expression of Superoxide dismutase Mn (SOD Mn). | [22], [981] | ||
Tyrosine-protein kinase Mer (MERTK)
MK-2461 [Phase 1/2]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for MK-2461. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MK-2461 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [982] | ||
ONO-7475 [Phase 1/2]
In total 2 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for ONO-7475. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ONO-7475 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [374] | ||
Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for ONO-7475. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ONO-7475 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [984] | |||
INCB81776 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for INCB81776. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of INCB81776 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [863] | ||
MRX-2843 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for MRX-2843. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of MRX-2843 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [983] | ||
PF-07265807 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for PF-07265807. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of PF-07265807 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [985] | ||
RXDX-106 [Phase 1]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for RXDX-106. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of RXDX-106 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [986] | ||
G749 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for G749. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of G749 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [987] | ||
LDC1267 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for LDC1267. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of LDC1267 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [988] | ||
UNC2025 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for UNC2025. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of UNC2025 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [38], [149] | ||
UNC569 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Tyrosine-protein kinase Mer (MERTK) is a therapeutic target for UNC569. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of UNC569 through regulating the expression of Tyrosine-protein kinase Mer (MERTK). | [149], [989] | ||
VCAM-1 messenger RNA (VCAM1 mRNA)
ISIS 3792 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 3792. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 3792 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
ISIS 3801 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 3801. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 3801 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
ISIS 3804 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 3804. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 3804 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [991] | ||
ISIS 3805 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 3805. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 3805 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
ISIS 5874 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 5874. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 5874 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
ISIS 5875 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 5875. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 5875 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
ISIS 5876 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 5876. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 5876 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
ISIS 5884 [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for ISIS 5884. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of ISIS 5884 through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [990] | ||
SYMBIOPOLYOL [Investigative]
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | VCAM-1 messenger RNA (VCAM1 mRNA) is a therapeutic target for SYMBIOPOLYOL. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of SYMBIOPOLYOL through regulating the expression of VCAM-1 messenger RNA (VCAM1 mRNA). | [592], [992] | ||
References