m6A-centered Drug Response Information
General Information of the Drug (ID: M6ADRUG0154)
| Name |
Etoposide
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| Synonyms |
33419-42-0; VePesid; Toposar; trans-Etoposide; Lastet; (-)-Etoposide; Zuyeyidal; Etoposidum; Etoposido; Vepesid J; Eposin; Etoposidum [INN-Latin]; Etoposide (VP16); VP 16-213; VP 16 (pharmaceutical); Etoposido [INN-Spanish]; Etopophos (phosphate salt); VP-16-213; 4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside; VP 16213; UNII-6PLQ3CP4P3; NK 171; NSC 141540; CCRIS 2392; HSDB 6517; 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside); EINECS 251-509-1; NSC-141540; Eposide; Etopol; Etosid; Vepeside; Demethyl EpipodophyllotoxinEthylidine Glucoside; E0675; Demethyl-epiodophyllotoxin ethylidene glucoside; Epipodophyllotoxin VP-16213; Eposin (TN); Etopophos (TN); VePESID (TN); DEMETHY-EPIPODOPHYLLOTOXIN, ETHYLIDENE GLUCOSIDE; VP-16 (TN); Demethylepipodophyllotoxin-beta-D-ethylideneglucoside; Etoposide (JP15/USP/INN); Etoposide [USAN:INN:BAN:JAN]; Eposin, Vepesid, VP-16, Toposar, Etoposide; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI); Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside; 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethylepipodophyllotoxin ethylidene-beta-D-glucoside; 4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin; 4-Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
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| Structure |
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3D MOL
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| Formula |
C29H32O13
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| InChI |
1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
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| InChIKey |
VJJPUSNTGOMMGY-MRVIYFEKSA-N
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Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
| In total 3 item(s) under this drug | ||
| Crosstalk ID: M6ACROT06038 | ||
| m6A Regulator | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) | |
| m6A Target | RNA component of 7SK nuclear ribonucleoprotein (RN7SK) | |
| Epigenetic Regulator | RNA component of 7SK nuclear ribonucleoprotein (RN7SK) | |
| Regulated Target | Cullin 1 (CUL1) | |
| Crosstalk relationship | m6A → ncRNA | |
| Crosstalk ID: M6ACROT06039 | ||
| m6A Regulator | Methyltransferase-like 3 (METTL3) | |
| m6A Target | RNA component of 7SK nuclear ribonucleoprotein (RN7SK) | |
| Epigenetic Regulator | RNA component of 7SK nuclear ribonucleoprotein (RN7SK) | |
| Regulated Target | Cullin 1 (CUL1) | |
| Crosstalk relationship | m6A → ncRNA | |
| Crosstalk ID: M6ACROT06040 | ||
| m6A Regulator | YTH domain-containing protein 2 (YTHDC2) | |
| m6A Target | RNA component of 7SK nuclear ribonucleoprotein (RN7SK) | |
| Epigenetic Regulator | RNA component of 7SK nuclear ribonucleoprotein (RN7SK) | |
| Regulated Target | Cullin 1 (CUL1) | |
| Crosstalk relationship | m6A → ncRNA | |