m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00267)

Target Name	Zinc finger protein GLI1 (GLI1)
Synonyms	Glioma-associated oncogene; Oncogene GLI; GLI Click to Show/Hide
Gene Name	GLI1
Chromosomal Location	12q13.3
Family	GLI C2H2-type zinc-finger protein family
Function	Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling. [Isoform 2]: Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH signaling. Promotes cancer cell migration. Click to Show/Hide
Gene ID	2735
Uniprot ID	GLI1_HUMAN
HGNC ID	HGNC:4317
KEGG ID	hsa:2735

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

GLI1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	HUVEC cell line	Homo sapiens
Treatment: shMETTL3 HUVEC cells Control: shScramble HUVEC cells		GSE157544
Regulation		logFC: 7.30E-01 p-value: 2.91E-03
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between GLI1 and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 7.23E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	METTL3 silence decreased the m6A modification and expression of Zinc finger protein GLI1 (GLI1), an important component of hedgehog pathway, which led to cell apoptosis.the m6A methyltransferase METTL3 promotes the growth and motility of prostate cancer cells by regulating hedgehog pathway.
Target Regulation	Up regulation
Responsed Disease	Prostate cancer		ICD-11: 2C82	Disease Info
Pathway Response	Hedgehog signaling pathway			hsa04340
Cell Process	Cell proliferation
	Cell survival
	Cell colony formation
	Cell invasion
In-vitro Model	LNCaP C4-2	Prostate carcinoma	Homo sapiens	CVCL_4782
	LNCaP C4-2B	Prostate carcinoma	Homo sapiens	CVCL_4784
	DU145	Prostate carcinoma	Homo sapiens	CVCL_0105
	LNCaP	Prostate carcinoma	Homo sapiens	CVCL_0395
	PC-3	Prostate carcinoma	Homo sapiens	CVCL_0035
In-vivo Model	Equal number of PC-3 cells was injected subcutaneously into right flank.

Prostate cancer [ICD-11: 2C82]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	METTL3 silence decreased the m6A modification and expression of Zinc finger protein GLI1 (GLI1), an important component of hedgehog pathway, which led to cell apoptosis.the m6A methyltransferase METTL3 promotes the growth and motility of prostate cancer cells by regulating hedgehog pathway.
Responsed Disease	Prostate cancer [ICD-11: 2C82]
Target Regulator	Methyltransferase-like 3 (METTL3)		WRITER	Regulator Info
Target Regulation	Up regulation
Pathway Response	Hedgehog signaling pathway			hsa04340
Cell Process	Cell proliferation
	Cell survival
	Cell colony formation
	Cell invasion
In-vitro Model	LNCaP C4-2	Prostate carcinoma	Homo sapiens	CVCL_4782
	LNCaP C4-2B	Prostate carcinoma	Homo sapiens	CVCL_4784
	DU145	Prostate carcinoma	Homo sapiens	CVCL_0105
	LNCaP	Prostate carcinoma	Homo sapiens	CVCL_0395
	PC-3	Prostate carcinoma	Homo sapiens	CVCL_0035
In-vivo Model	Equal number of PC-3 cells was injected subcutaneously into right flank.

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05889		Crosstalk Info
Epigenetic Regulator	Long intergenic non-protein coding RNA 1093 (LINC01093)
Regulated Target	Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1)
Crosstalk relationship	ncRNA → m6A
Disease	Hepatocellular carcinoma	Disease Info
Crosstalk ID: M6ACROT05893		Crosstalk Info
Epigenetic Regulator	Testis associated oncogenic lncRNA (THORLNC)
Regulated Target	Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1)
Crosstalk relationship	ncRNA → m6A
Disease	Nasopharyngeal carcinoma	Disease Info
Drug	Triptonide	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00267)

Zinc finger protein GLI1 (GLI1)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE005629		Click to Show/Hide the Full List
mod site	chr12:57470840-57470841:+		[4]
Sequence	AGAATGCTGCCATGGATGCTAGAGGGCTACAGGAAGAGCCA
Transcript ID List	ENST00000228682.7; ENST00000543426.5; ENST00000546141.5; ENST00000528467.1
External Link	RMBase: RNA-editing_site_29456

N6-methyladenosine (m6A)

In total 34 m6A sequence/site(s) in this target gene
mod ID: M6ASITE013560		Click to Show/Hide the Full List
mod site	chr12:57464759-57464760:+		[5]
Sequence	TCTGTCGGATGCCAGCCTGGACCTGCAGACGGTTATCCGCA
Motif Score	3.622404762
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000543426.5; ENST00000532291.5; ENST00000528467.1; ENST00000546141.5; ENST00000228682.7; ENST00000528432.1; ENST00000530789.1
External Link	RMBase: m6A_site_195033
mod ID: M6ASITE013561		Click to Show/Hide the Full List
mod site	chr12:57464939-57464940:+		[5]
Sequence	TAAAAGTCTCAAGCCCTCAAACTACCTAACCCTATTTGAAT
Motif Score	2.627720238
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000530789.1; ENST00000528467.1; ENST00000228682.7; ENST00000546141.5; ENST00000543426.5; ENST00000532291.5
External Link	RMBase: m6A_site_195034
mod ID: M6ASITE013562		Click to Show/Hide the Full List
mod site	chr12:57466358-57466359:+		[6]
Sequence	CTGGTGGTTCACATGCGCAGACACACTGGCGAGAAGCCACA
Motif Score	2.897386905
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000546141.5; ENST00000532291.5; ENST00000543426.5; ENST00000528467.1; ENST00000228682.7
External Link	RMBase: m6A_site_195035
mod ID: M6ASITE013563		Click to Show/Hide the Full List
mod site	chr12:57467369-57467370:+		[6]
Sequence	GTCATACTCACGCCTCGAAAACCTGAAGACGCACCTGCGGT
Motif Score	2.185083333
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000528467.1; ENST00000228682.7; ENST00000543426.5; ENST00000546141.5
External Link	RMBase: m6A_site_195036
mod ID: M6ASITE013564		Click to Show/Hide the Full List
mod site	chr12:57468199-57468200:+		[6]
Sequence	CCCATCAGGGAGGAAAGCAGACTGACTGTGCCAGAGGGTGC
Motif Score	3.319380952
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000546141.5; ENST00000528467.1; ENST00000228682.7; ENST00000543426.5
External Link	RMBase: m6A_site_195037
mod ID: M6ASITE013565		Click to Show/Hide the Full List
mod site	chr12:57469506-57469507:+		[7]
Sequence	AGGGAGTGCAGCCAATACAGACAGTGGTGTGGAAATGACTG
Motif Score	2.897386905
Cell/Tissue List	H1A; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000546141.5; ENST00000228682.7; ENST00000543426.5; ENST00000528467.1
External Link	RMBase: m6A_site_195038
mod ID: M6ASITE013566		Click to Show/Hide the Full List
mod site	chr12:57469551-57469552:+		[7]
Sequence	TGCAGGGGGCAGCACTGAAGACCTCTCCAGCTTGGACGAGG
Motif Score	2.876744048
Cell/Tissue List	H1A; H1B; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000528467.1; ENST00000543426.5; ENST00000228682.7; ENST00000546141.5
External Link	RMBase: m6A_site_195039
mod ID: M6ASITE013567		Click to Show/Hide the Full List
mod site	chr12:57469573-57469574:+		[7]
Sequence	CTCTCCAGCTTGGACGAGGGACCTTGCATTGCTGGCACTGG
Motif Score	3.622404762
Cell/Tissue List	H1A; H1B; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000546141.5; ENST00000543426.5; ENST00000228682.7; ENST00000528467.1
External Link	RMBase: m6A_site_195040
mod ID: M6ASITE013568		Click to Show/Hide the Full List
mod site	chr12:57469620-57469621:+		[7]
Sequence	CACTCTTCGCCGCCTTGAGAACCTCAGGCTGGACCAGCTAC
Motif Score	2.930744048
Cell/Tissue List	H1A; H1B; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000528467.1; ENST00000228682.7; ENST00000546141.5; ENST00000543426.5
External Link	RMBase: m6A_site_195041
mod ID: M6ASITE013569		Click to Show/Hide the Full List
mod site	chr12:57469632-57469633:+		[7]
Sequence	CCTTGAGAACCTCAGGCTGGACCAGCTACATCAACTCCGGC
Motif Score	3.622404762
Cell/Tissue List	H1A; H1B; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000228682.7; ENST00000543426.5; ENST00000546141.5; ENST00000528467.1
External Link	RMBase: m6A_site_195042
mod ID: M6ASITE013570		Click to Show/Hide the Full List
mod site	chr12:57469661-57469662:+		[7]
Sequence	ATCAACTCCGGCCAATAGGGACCCGGGGTCTCAAACTGCCC
Motif Score	3.622404762
Cell/Tissue List	H1A; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000543426.5; ENST00000546141.5; ENST00000528467.1; ENST00000228682.7
External Link	RMBase: m6A_site_195043
mod ID: M6ASITE013571		Click to Show/Hide the Full List
mod site	chr12:57469675-57469676:+		[6]
Sequence	ATAGGGACCCGGGGTCTCAAACTGCCCAGCTTGTCCCACAC
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000546141.5; ENST00000528467.1; ENST00000543426.5; ENST00000228682.7
External Link	RMBase: m6A_site_195044
mod ID: M6ASITE013572		Click to Show/Hide the Full List
mod site	chr12:57470758-57470759:+		[8]
Sequence	CCCACTGTGGCAGGGGGAGGACAGAACTTTGATCCTTACCT
Motif Score	3.643047619
Cell/Tissue List	A549; U2OS; H1B; hESCs; GSC-11; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000543426.5; ENST00000546141.5; ENST00000528467.1; ENST00000228682.7
External Link	RMBase: m6A_site_195045
mod ID: M6ASITE013573		Click to Show/Hide the Full List
mod site	chr12:57470763-57470764:+		[8]
Sequence	TGTGGCAGGGGGAGGACAGAACTTTGATCCTTACCTCCCAA
Motif Score	3.373380952
Cell/Tissue List	A549; U2OS; H1B; hESCs; GSC-11; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000228682.7; ENST00000546141.5; ENST00000528467.1; ENST00000543426.5
External Link	RMBase: m6A_site_195046
mod ID: M6ASITE013574		Click to Show/Hide the Full List
mod site	chr12:57470870-57470871:+		[9]
Sequence	AGGAAGAGCCAGAAGTTGGGACCTCCATGGTGGGCAGTGGT
Motif Score	3.622404762
Cell/Tissue List	HeLa; A549; U2OS; H1A; H1B; hESCs; peripheral-blood; GSC-11; HEK293A-TOA; MSC; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543426.5; ENST00000228682.7; ENST00000546141.5; ENST00000528467.1
External Link	RMBase: m6A_site_195047
mod ID: M6ASITE013575		Click to Show/Hide the Full List
mod site	chr12:57470895-57470896:+		[9]
Sequence	CATGGTGGGCAGTGGTCTGAACCCCTATATGGACTTCCCAC
Motif Score	2.930744048
Cell/Tissue List	HeLa; A549; U2OS; H1A; H1B; hESCs; peripheral-blood; GSC-11; HEK293A-TOA; MSC; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000228682.7; ENST00000546141.5; ENST00000543426.5; ENST00000528467.1
External Link	RMBase: m6A_site_195048
mod ID: M6ASITE013576		Click to Show/Hide the Full List
mod site	chr12:57470907-57470908:+		[9]
Sequence	TGGTCTGAACCCCTATATGGACTTCCCACCTACTGATACTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; U2OS; H1A; H1B; hESCs; peripheral-blood; GSC-11; HEK293A-TOA; MSC; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000228682.7; ENST00000546141.5; ENST00000543426.5; ENST00000528467.1
External Link	RMBase: m6A_site_195049
mod ID: M6ASITE013577		Click to Show/Hide the Full List
mod site	chr12:57470941-57470942:+		[9]
Sequence	GATACTCTGGGATATGGGGGACCTGAAGGGGCAGCAGCTGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; H1A; H1B; hESCs; peripheral-blood; GSC-11; HEK293A-TOA; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000528467.1; ENST00000546141.5; ENST00000228682.7; ENST00000543426.5
External Link	RMBase: m6A_site_195050
mod ID: M6ASITE013578		Click to Show/Hide the Full List
mod site	chr12:57471074-57471075:+		[8]
Sequence	ATCCTGACCCCACCCAAGAAACATGGGGTGAGTTCCCTTCC
Motif Score	2.20572619
Cell/Tissue List	HEK293T; A549; U2OS; H1A; H1B; hESCs; GSC-11; TREX; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000228682.7; ENST00000528467.1; ENST00000546141.5; ENST00000543426.5
External Link	RMBase: m6A_site_195051
mod ID: M6ASITE013579		Click to Show/Hide the Full List
mod site	chr12:57471134-57471135:+		[8]
Sequence	GCCCCAAGGCTCTAGGTGGAACCTACAGCCAGTGTCCTCGA
Motif Score	2.930744048
Cell/Tissue List	A549; HEK293T; U2OS; H1A; H1B; hESCs; Huh7; GSC-11; HEK293A-TOA; TREX; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000543426.5; ENST00000528467.1; ENST00000228682.7; ENST00000546141.5
External Link	RMBase: m6A_site_195052
mod ID: M6ASITE013580		Click to Show/Hide the Full List
mod site	chr12:57471160-57471161:+		[8]
Sequence	AGCCAGTGTCCTCGACTTGAACATTATGGACAAGTGCAAGT
Motif Score	2.951386905
Cell/Tissue List	A549; HEK293T; U2OS; H1A; H1B; hESCs; GM12878; Huh7; GSC-11; HEK293A-TOA; MSC; TREX; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000228682.7; ENST00000528467.1; ENST00000546141.5; ENST00000543426.5
External Link	RMBase: m6A_site_195053
mod ID: M6ASITE013581		Click to Show/Hide the Full List
mod site	chr12:57471169-57471170:+		[8]
Sequence	CCTCGACTTGAACATTATGGACAAGTGCAAGTCAAGCCAGA
Motif Score	3.643047619
Cell/Tissue List	A549; HEK293T; U2OS; H1A; H1B; hESCs; GM12878; Huh7; GSC-11; HEK293A-TOA; MSC; TREX; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000528467.1; ENST00000543426.5; ENST00000546141.5; ENST00000228682.7
External Link	RMBase: m6A_site_195054
mod ID: M6ASITE013582		Click to Show/Hide the Full List
mod site	chr12:57471190-57471191:+		[8]
Sequence	CAAGTGCAAGTCAAGCCAGAACAGGGGTGCCCAGTGGGGTC
Motif Score	2.951386905
Cell/Tissue List	A549; HEK293T; U2OS; H1A; H1B; hESCs; GM12878; Huh7; GSC-11; HEK293A-TOA; MSC; TREX; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000528467.1; ENST00000546141.5; ENST00000543426.5; ENST00000228682.7
External Link	RMBase: m6A_site_195055
mod ID: M6ASITE013583		Click to Show/Hide the Full List
mod site	chr12:57471223-57471224:+		[8]
Sequence	GTGGGGTCTGACTCCACAGGACTGGCACCCTGCCTCAATGC
Motif Score	4.065041667
Cell/Tissue List	A549; HEK293T; U2OS; H1A; H1B; hESCs; GM12878; Huh7; GSC-11; HEK293A-TOA; MSC; TREX; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000528467.1; ENST00000546141.5; ENST00000228682.7; ENST00000543426.5
External Link	RMBase: m6A_site_195056
mod ID: M6ASITE013584		Click to Show/Hide the Full List
mod site	chr12:57471367-57471368:+		[8]
Sequence	CCTGATTATCTTCCTTCAGAACCCAGGCCTTGCCTGGACTT
Motif Score	2.930744048
Cell/Tissue List	A549; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000546141.5; ENST00000228682.7; ENST00000543426.5; ENST00000528467.1
External Link	RMBase: m6A_site_195057
mod ID: M6ASITE013585		Click to Show/Hide the Full List
mod site	chr12:57471384-57471385:+		[8]
Sequence	AGAACCCAGGCCTTGCCTGGACTTTGATTCCCCCACCCATT
Motif Score	4.065041667
Cell/Tissue List	A549; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000543426.5; ENST00000546141.5; ENST00000528467.1; ENST00000228682.7
External Link	RMBase: m6A_site_195058
mod ID: M6ASITE013586		Click to Show/Hide the Full List
mod site	chr12:57471586-57471587:+		[5]
Sequence	GCTCCAGTGAACACATATGGACCTGGCTTTGGACCCAACTT
Motif Score	3.622404762
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000543426.5; ENST00000528467.1; ENST00000546141.5; ENST00000228682.7
External Link	RMBase: m6A_site_195059
mod ID: M6ASITE013587		Click to Show/Hide the Full List
mod site	chr12:57471598-57471599:+		[5]
Sequence	ACATATGGACCTGGCTTTGGACCCAACTTGCCCAATCACAA
Motif Score	3.622404762
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000228682.7; ENST00000528467.1; ENST00000543426.5; ENST00000546141.5
External Link	RMBase: m6A_site_195060
mod ID: M6ASITE013588		Click to Show/Hide the Full List
mod site	chr12:57471762-57471763:+		[9]
Sequence	TCTCAAAGTGGGAGGCACAAACCCCAGCTGTGGTCATCCTG
Motif Score	2.185083333
Cell/Tissue List	HeLa; U2OS; A549
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543426.5; ENST00000546141.5; ENST00000528467.1; ENST00000228682.7
External Link	RMBase: m6A_site_195061
mod ID: M6ASITE013589		Click to Show/Hide the Full List
mod site	chr12:57471832-57471833:+		[9]
Sequence	TTGTACCCTCCTCCCGAAGGACAGGTATGTAACCCCCTGGA
Motif Score	3.643047619
Cell/Tissue List	HeLa; A549; U2OS; H1A; H1B; hESCs; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000546141.5; ENST00000528467.1; ENST00000228682.7; ENST00000543426.5
External Link	RMBase: m6A_site_195062
mod ID: M6ASITE013590		Click to Show/Hide the Full List
mod site	chr12:57471852-57471853:+		[9]
Sequence	ACAGGTATGTAACCCCCTGGACTCTCTTGATCTTGACAACA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; H1A; H1B; hESCs; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000546141.5; ENST00000228682.7; ENST00000543426.5; ENST00000528467.1
External Link	RMBase: m6A_site_195063
mod ID: M6ASITE013591		Click to Show/Hide the Full List
mod site	chr12:57471882-57471883:+		[9]
Sequence	TCTTGACAACACTCAGCTGGACTTTGTGGCTATTCTGGATG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; A549; H1A; H1B; hESCs; GSC-11; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000228682.7; ENST00000543426.5; ENST00000528467.1; ENST00000546141.5
External Link	RMBase: m6A_site_195064
mod ID: M6ASITE013592		Click to Show/Hide the Full List
mod site	chr12:57471955-57471956:+		[8]
Sequence	GATCAGCGGGGCAGCTCTGGACATACCCCACCTCCCTCTGG
Motif Score	3.643047619
Cell/Tissue List	HEK293T; A549; H1A; H1B; GSC-11; TREX; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000228682.7; ENST00000543426.5; ENST00000528467.1; ENST00000546141.5
External Link	RMBase: m6A_site_195065
mod ID: M6ASITE013593		Click to Show/Hide the Full List
mod site	chr12:57472034-57472035:+		[8]
Sequence	TGAGATCCCTACCTGGGGAAACAGAATTCCTCAACTCTAGT
Motif Score	2.20572619
Cell/Tissue List	A549; H1B; GSC-11
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000543426.5; ENST00000228682.7; ENST00000528467.1; ENST00000546141.5
External Link	RMBase: m6A_site_195066

Ref 1	RNA m(6)A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway. Onco Targets Ther. 2019 Nov 5;12:9143-9152. doi: 10.2147/OTT.S226796. eCollection 2019.
Ref 2	Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism. Clin Pharmacol Ther. 2005 Aug;78(2):191-201. doi: 10.1016/j.clpt.2005.04.012.
Ref 3	Several major antiepileptic drugs are substrates for human P-glycoprotein. Neuropharmacology. 2008 Dec;55(8):1364-75. doi: 10.1016/j.neuropharm.2008.08.032. Epub 2008 Sep 11.
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m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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