m6A-centered Drug Response Information
General Information of the Drug (ID: M6ADRUG0174)
| Name |
Chidamide
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| Synonyms |
743420-02-2, 1883690-47-8, 462284YV3M, UNII-462284YV3M, Benzamide, N-(2-amino-5-fluorophenyl)-4-(((1-oxo-3-(3-pyridinyl)-2-propen-1-yl)amino)methyl)-, N-(2-Amino-5-fluorophenyl)-4-(((1-oxo-3-(3-pyridinyl)-2-propen-1-yl)amino)methyl)benzamide, N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide, Chidamide, HDAC-IN-7, N-(2-amino-5-fluorophenyl)-4-[[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]methyl]benzamide, CHEMBL4087968, (E)-N-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide, N-(2-Amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide, De-4-fluoro 5-Fluoro Chidamide, N-(2-Amino-4-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]benzamide; Isochidamide; (E)-N-(2-Amino-4-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide, MFCD18382123, Tucidinostat(Chidamide), SCHEMBL8057949, WXHHICFWKXDFOW-BJMVGYQFSA-N, DTXSID801348099, GLXC-05969, EX-A2209, Chidamide; CS055; HBI-8000, BDBM50242817, HBI-8000;CS-055, s8567, AKOS027339700, CCG-208658, CS-3554, NCGC00263598-10, AS-47017, BP-40079, HY-13592, F11457, BRD-K28537285-001-01-8, Q27075960, N-(2-Amino-5-fluorophenyl)-4-{[(2E)-3-(3-pyridinyl)-2-propenamido]methyl}benzamide
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| Structure |
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3D MOL
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| Formula |
C22H19FN4O2
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| InChI |
InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)/b10-5+
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| InChIKey |
WXHHICFWKXDFOW-BJMVGYQFSA-N
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| PubChem CID | |||||
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Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
| In total 5 item(s) under this drug | ||
| Crosstalk ID: M6ACROT02275 | ||
| m6A Regulator | Wilms tumor 1-associating protein (WTAP) | |
| m6A Target | GNAS antisense RNA 1 (GNAS-AS1) | |
| Regulated Target | hsa-miR-550-1 | |
| Crosstalk relationship | DNA modification → m6A | |
| Disease | Acute myeloid leukaemia | |
| Crosstalk ID: M6ACROT05668 | ||
| m6A Regulator | Wilms tumor 1-associating protein (WTAP) | |
| m6A Target | GNAS antisense RNA 1 (GNAS-AS1) | |
| Epigenetic Regulator | GNAS antisense RNA 1 (GNAS-AS1) | |
| Regulated Target | hsa-miR-34a-5p | |
| Crosstalk relationship | m6A → ncRNA | |
| Disease | Acute myeloid leukaemia | |
| Crosstalk ID: M6ACROT05833 | ||
| m6A Regulator | Methyltransferase-like 3 (METTL3) | |
| m6A Target | SREBF2 antisense RNA 1 (SREBF2-AS1) | |
| Epigenetic Regulator | SREBF2 antisense RNA 1 (SREBF2-AS1) | |
| Regulated Target | FMR1 autosomal homolog 1 (FXR1) | |
| Crosstalk relationship | m6A → ncRNA | |
| Disease | Acute myeloid leukaemia | |
| Crosstalk ID: M6ACROT05834 | ||
| m6A Regulator | Methyltransferase-like 14 (METTL14) | |
| m6A Target | SREBF2 antisense RNA 1 (SREBF2-AS1) | |
| Epigenetic Regulator | SREBF2 antisense RNA 1 (SREBF2-AS1) | |
| Regulated Target | FMR1 autosomal homolog 1 (FXR1) | |
| Crosstalk relationship | m6A → ncRNA | |
| Disease | Acute myeloid leukaemia | |
| Crosstalk ID: M6ACROT05928 | ||
| m6A Regulator | Wilms tumor 1-associating protein (WTAP) | |
| m6A Target | GNAS antisense RNA 1 (GNAS-AS1) | |
| Epigenetic Regulator | hsa-miR-34a-5p | |
| Regulated Target | Insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2) | |
| Crosstalk relationship | m6A → ncRNA | |
| Disease | Acute myeloid leukaemia | |