m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01536)

Target Name	Macrophage colony-stimulating factor 1 (CSF1)
Synonyms	CSF-1; M-CSF; MCSF; Lanimostim; Proteoglycan macrophage colony-stimulating factor; PG-M-CSF Click to Show/Hide
Gene Name	CSF1
Chromosomal Location	1p13.3
Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. Click to Show/Hide
Gene ID	1435
Uniprot ID	CSF1_HUMAN
HGNC ID	HGNC:2432
KEGG ID	hsa:1435

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

RNA modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT00461		Crosstalk Info
Epigenetic Regulator	Interferon-inducible protein 4 (ADAR1)
Regulated Target	MicroRNA 149 (MIR149)
Crosstalk relationship	A-to-I → m6A
Crosstalk ID: M6ACROT00462		Crosstalk Info
Epigenetic Regulator	Methyltransferase-like protein 1 (METTL1)
Regulated Target	MicroRNA 149 (MIR149)
Crosstalk relationship	m7G → m6A

Histone modification

m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03132		Crosstalk Info
Epigenetic Regulator	Histone acetyltransferase p300 (P300)
Regulated Target	Histone H3 lysine 18 lactylation (H3K18la)
Crosstalk relationship	Histone modification → m6A
Disease	Pancreatic cancer	Disease Info
Crosstalk ID: M6ACROT06041		Crosstalk Info
Epigenetic Regulator	Histone acetyltransferase p300 (P300)
Regulated Target	Histone H3 lysine 18 lactylation (H3K18la)
Crosstalk relationship	Histone modification → m6A
Disease	Pancreatic cancer	Disease Info
Drug	Gemcitabine	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01536)

Macrophage colony-stimulating factor 1 (CSF1)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE009652		Click to Show/Hide the Full List
mod site	chr1:109916680-109916681:+		[2]
Sequence	TATGCACCTCTGTTAGGACTAGAGATCACCTCATGGTCCAA
Transcript ID List	ENST00000526001.1; ENST00000420111.6; ENST00000369801.1; ENST00000525659.5; ENST00000527192.5; ENST00000369802.7; ENST00000488198.5; ENST00000357302.8; ENST00000329608.11
External Link	RMBase: RNA-editing_site_7654

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002925		Click to Show/Hide the Full List
mod site	chr1:109914339-109914340:+		[3]
Sequence	AGGTGTCGGAGTACTGTAGCCACATGATTGGGAGTGGACAC
Cell/Tissue List	frontalcortex; T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000369801.1; ENST00000329608.11; ENST00000357302.8; ENST00000420111.6; ENST00000488198.5; ENST00000525659.5; ENST00000527192.5; ENST00000369802.7
External Link	RMBase: m5C_site_3097

N6-methyladenosine (m6A)

In total 66 m6A sequence/site(s) in this target gene
mod ID: M6ASITE041419		Click to Show/Hide the Full List
mod site	chr1:109910625-109910626:+		[4]
Sequence	TTGGAAGTGCAGCGCAGAAGACAGAGGGTGACTAGGAAGAC
Motif Score	2.897386905
Cell/Tissue List	HeLa; GSC-11; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000527192.5; ENST00000357302.8; ENST00000525659.5
External Link	RMBase: m6A_site_44198
mod ID: M6ASITE041420		Click to Show/Hide the Full List
mod site	chr1:109910920-109910921:+		[4]
Sequence	GCCGCTCTCCGCATCCCAGGACAGCGGTGCGGCCCTCGGCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; CD4T; GSC-11; HEK293T; endometrial; GSCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000357302.8; ENST00000527192.5; ENST00000369802.7; ENST00000420111.6; ENST00000525659.5; ENST00000488198.5; ENST00000329608.11
External Link	RMBase: m6A_site_44199
mod ID: M6ASITE041421		Click to Show/Hide the Full List
mod site	chr1:109911009-109911010:+		[5]
Sequence	GGCCGACGCGCCCGGCCGGGACCCAGCTGCCCGTATGACCG
Motif Score	3.622404762
Cell/Tissue List	GSC-11; HEK293T; GSCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000420111.6; ENST00000525659.5; ENST00000488198.5; ENST00000357302.8; ENST00000369802.7; ENST00000329608.11; ENST00000527192.5; ENST00000369801.1
External Link	RMBase: m6A_site_44200
mod ID: M6ASITE041422		Click to Show/Hide the Full List
mod site	chr1:109915651-109915652:+		[4]
Sequence	AGATTGACAGTCAGATGGAGACCTCGTGCCAAATTACATTT
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000525659.5; ENST00000488198.5; ENST00000369802.7; ENST00000369801.1; ENST00000420111.6; ENST00000357302.8; ENST00000329608.11; ENST00000527192.5
External Link	RMBase: m6A_site_44201
mod ID: M6ASITE041423		Click to Show/Hide the Full List
mod site	chr1:109915682-109915683:+		[4]
Sequence	AATTACATTTGAGTTTGTAGACCAGGAACAGTTGGTGAGTG
Motif Score	2.876744048
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000488198.5; ENST00000369801.1; ENST00000525659.5; ENST00000369802.7; ENST00000526001.1; ENST00000329608.11; ENST00000357302.8; ENST00000420111.6; ENST00000527192.5
External Link	RMBase: m6A_site_44202
mod ID: M6ASITE041424		Click to Show/Hide the Full List
mod site	chr1:109915689-109915690:+		[4]
Sequence	TTTGAGTTTGTAGACCAGGAACAGTTGGTGAGTGATGGCTT
Motif Score	2.951386905
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000420111.6; ENST00000369802.7; ENST00000357302.8; ENST00000488198.5; ENST00000527192.5; ENST00000526001.1; ENST00000329608.11; ENST00000369801.1; ENST00000525659.5
External Link	RMBase: m6A_site_44203
mod ID: M6ASITE041425		Click to Show/Hide the Full List
mod site	chr1:109917338-109917339:+		[4]
Sequence	GGCATTTCTCCTGGTACAAGACATAATGGAGGACACCATGC
Motif Score	2.897386905
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000488198.5; ENST00000420111.6; ENST00000369802.7; ENST00000329608.11; ENST00000357302.8; ENST00000525659.5; ENST00000526001.1; ENST00000527192.5; ENST00000369801.1
External Link	RMBase: m6A_site_44204
mod ID: M6ASITE041426		Click to Show/Hide the Full List
mod site	chr1:109917350-109917351:+		[4]
Sequence	GGTACAAGACATAATGGAGGACACCATGCGCTTCAGAGATA
Motif Score	3.643047619
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000525659.5; ENST00000420111.6; ENST00000527192.5; ENST00000329608.11; ENST00000369801.1; ENST00000526001.1; ENST00000357302.8; ENST00000369802.7; ENST00000488198.5
External Link	RMBase: m6A_site_44205
mod ID: M6ASITE041427		Click to Show/Hide the Full List
mod site	chr1:109917408-109917409:+		[4]
Sequence	GCCATTGTGCAGCTGCAGGAACTCTCTTTGAGGCTGAAGAG
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000369801.1; ENST00000420111.6; ENST00000488198.5; ENST00000526001.1; ENST00000525659.5; ENST00000329608.11; ENST00000527192.5; ENST00000369802.7; ENST00000357302.8
External Link	RMBase: m6A_site_44206
mod ID: M6ASITE041428		Click to Show/Hide the Full List
mod site	chr1:109921858-109921859:+		[4]
Sequence	CCTTCCAGGCCTGCGTCCGAACTTTCTATGAGACACCTCTC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000525659.5; ENST00000527192.5; ENST00000526001.1; ENST00000420111.6; ENST00000329608.11; ENST00000369801.1; ENST00000488198.5; ENST00000369802.7
External Link	RMBase: m6A_site_44207
mod ID: M6ASITE041429		Click to Show/Hide the Full List
mod site	chr1:109921870-109921871:+		[4]
Sequence	GCGTCCGAACTTTCTATGAGACACCTCTCCAGTTGCTGGAG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000525659.5; ENST00000488198.5; ENST00000369801.1; ENST00000420111.6; ENST00000369802.7; ENST00000526001.1; ENST00000527192.5; ENST00000329608.11
External Link	RMBase: m6A_site_44208
mod ID: M6ASITE041430		Click to Show/Hide the Full List
mod site	chr1:109921915-109921916:+		[4]
Sequence	TCAAGAATGTCTTTAATGAAACAAAGAATCTCCTTGACAAG
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000420111.6; ENST00000488198.5; ENST00000369802.7; ENST00000526001.1; ENST00000369801.1; ENST00000329608.11
External Link	RMBase: m6A_site_44209
mod ID: M6ASITE041431		Click to Show/Hide the Full List
mod site	chr1:109921937-109921938:+		[4]
Sequence	AAAGAATCTCCTTGACAAGGACTGGAATATTTTCAGCAAGA
Motif Score	4.065041667
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000329608.11; ENST00000369801.1; ENST00000488198.5; ENST00000369802.7; ENST00000420111.6; ENST00000526001.1
External Link	RMBase: m6A_site_44210
mod ID: M6ASITE041432		Click to Show/Hide the Full List
mod site	chr1:109921958-109921959:+		[4]
Sequence	CTGGAATATTTTCAGCAAGAACTGCAACAACAGCTTTGCTG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; Huh7; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000329608.11; ENST00000369801.1; ENST00000420111.6; ENST00000488198.5; ENST00000526001.1
External Link	RMBase: m6A_site_44211
mod ID: M6ASITE041433		Click to Show/Hide the Full List
mod site	chr1:109922366-109922367:+		[4]
Sequence	GTGTGGGGGGTTCTGTGGAGACAGCTGACACCCATCTGGGA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; Huh7; HEK293A-TOA; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11; ENST00000369801.1; ENST00000526001.1; ENST00000488198.5; ENST00000369802.7; ENST00000420111.6
External Link	RMBase: m6A_site_44212
mod ID: M6ASITE041434		Click to Show/Hide the Full List
mod site	chr1:109922479-109922480:+		[4]
Sequence	CTTGGGTGTTTCCTCAAGGGACAAGGCTGGATTTGAAGTCT
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000526001.1; ENST00000420111.6; ENST00000488198.5; ENST00000329608.11; ENST00000369801.1; ENST00000369802.7
External Link	RMBase: m6A_site_44213
mod ID: M6ASITE041435		Click to Show/Hide the Full List
mod site	chr1:109922513-109922514:+		[4]
Sequence	GAAGTCTGAGCATCATTGGAACTCCCAGGGCTGGCTCAGCT
Motif Score	3.373380952
Cell/Tissue List	HeLa; Huh7; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000526001.1; ENST00000420111.6; ENST00000329608.11; ENST00000488198.5; ENST00000369802.7; ENST00000369801.1
External Link	RMBase: m6A_site_44214
mod ID: M6ASITE041436		Click to Show/Hide the Full List
mod site	chr1:109923294-109923295:+		[4]
Sequence	GGCTGGCTTGACCTGGGAGGACTCTGAGGGAACTGAGGGCA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; GM12878; LCLs; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000369801.1; ENST00000420111.6; ENST00000329608.11; ENST00000488198.5
External Link	RMBase: m6A_site_44215
mod ID: M6ASITE041437		Click to Show/Hide the Full List
mod site	chr1:109923305-109923306:+		[4]
Sequence	CCTGGGAGGACTCTGAGGGAACTGAGGGCAGCTCCCTCTTG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; GM12878; LCLs; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11; ENST00000369802.7; ENST00000420111.6; ENST00000488198.5; ENST00000369801.1
External Link	RMBase: m6A_site_44216
mod ID: M6ASITE041438		Click to Show/Hide the Full List
mod site	chr1:109923416-109923417:+		[4]
Sequence	AGAGCTTTGAGCCGCCAGAGACCCCAGTTGTCAAGGACAGC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000488198.5; ENST00000369801.1; ENST00000369802.7; ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44217
mod ID: M6ASITE041439		Click to Show/Hide the Full List
mod site	chr1:109923432-109923433:+		[4]
Sequence	AGAGACCCCAGTTGTCAAGGACAGCACCATCGGTGGCTCAC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000369801.1; ENST00000488198.5; ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44218
mod ID: M6ASITE041440		Click to Show/Hide the Full List
mod site	chr1:109923581-109923582:+		[4]
Sequence	AGATTCCCGTACCCCAAGGGACAGAGCTTTCCCCCTCCAGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; H1A; hNPCs; fibroblasts; GM12878; LCLs; MM6; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000420111.6; ENST00000329608.11; ENST00000369802.7; ENST00000488198.5; ENST00000369801.1
External Link	RMBase: m6A_site_44219
mod ID: M6ASITE041441		Click to Show/Hide the Full List
mod site	chr1:109923623-109923624:+		[4]
Sequence	CAGGAGGGGGCAGCATGCAGACAGAGCCCGCCAGACCCAGC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; H1A; hNPCs; fibroblasts; GM12878; LCLs; MM6; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000369801.1; ENST00000420111.6; ENST00000329608.11
External Link	RMBase: m6A_site_44220
mod ID: M6ASITE041442		Click to Show/Hide the Full List
mod site	chr1:109923637-109923638:+		[4]
Sequence	ATGCAGACAGAGCCCGCCAGACCCAGCAACTTCCTCTCAGC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; H1A; hNPCs; fibroblasts; GM12878; LCLs; MM6; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000420111.6; ENST00000369801.1; ENST00000329608.11
External Link	RMBase: m6A_site_44221
mod ID: M6ASITE041443		Click to Show/Hide the Full List
mod site	chr1:109923691-109923692:+		[6]
Sequence	CCTGCATCAGCAAAGGGCCAACAGCCGGCAGATGTAACTGG
Motif Score	2.173910714
Cell/Tissue List	brain; kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000369801.1; ENST00000329608.11; ENST00000369802.7; ENST00000420111.6
External Link	RMBase: m6A_site_44222
mod ID: M6ASITE041444		Click to Show/Hide the Full List
mod site	chr1:109923756-109923757:+		[4]
Sequence	CGTGAGGCCCACTGGCCAGGACTGGAATCACACCCCCCAGA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000369802.7; ENST00000420111.6; ENST00000369801.1; ENST00000329608.11
External Link	RMBase: m6A_site_44223
mod ID: M6ASITE041445		Click to Show/Hide the Full List
mod site	chr1:109923779-109923780:+		[4]
Sequence	GGAATCACACCCCCCAGAAGACAGACCATCCATCTGCCCTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000329608.11; ENST00000420111.6; ENST00000369801.1
External Link	RMBase: m6A_site_44224
mod ID: M6ASITE041446		Click to Show/Hide the Full List
mod site	chr1:109923807-109923808:+		[4]
Sequence	TCCATCTGCCCTGCTCAGAGACCCCCCGGAGCCAGGCTCTC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000420111.6; ENST00000329608.11; ENST00000369801.1; ENST00000369802.7
External Link	RMBase: m6A_site_44225
mod ID: M6ASITE041447		Click to Show/Hide the Full List
mod site	chr1:109923994-109923995:+		[4]
Sequence	CCCGCAGAGCCAGAAGGAGGACCAGCAAGTGAAGGGGCAGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000420111.6; ENST00000369802.7; ENST00000329608.11; ENST00000369801.1
External Link	RMBase: m6A_site_44226
mod ID: M6ASITE041448		Click to Show/Hide the Full List
mod site	chr1:109925167-109925168:+		[4]
Sequence	CCCCTGACTCAGGATGACAGACAGGTGGAACTGCCAGTGTA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; GSC-11; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000329608.11; ENST00000369801.1; ENST00000420111.6
External Link	RMBase: m6A_site_44227
mod ID: M6ASITE041449		Click to Show/Hide the Full List
mod site	chr1:109925176-109925177:+		[4]
Sequence	CAGGATGACAGACAGGTGGAACTGCCAGTGTAGAGGGAATT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; GSC-11; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11; ENST00000369801.1; ENST00000420111.6; ENST00000369802.7
External Link	RMBase: m6A_site_44228
mod ID: M6ASITE041450		Click to Show/Hide the Full List
mod site	chr1:109926079-109926080:+		[4]
Sequence	CAGACCCCTCACCATCCTGGACACACTCGTTTGTCAATGTC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; GSC-11; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11; ENST00000420111.6; ENST00000369802.7
External Link	RMBase: m6A_site_44229
mod ID: M6ASITE041451		Click to Show/Hide the Full List
mod site	chr1:109926128-109926129:+		[4]
Sequence	AATGTGACGCCCAGCCCCGGACACAGTACTCCAGATGTTGT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000369802.7; ENST00000420111.6; ENST00000329608.11
External Link	RMBase: m6A_site_44230
mod ID: M6ASITE041452		Click to Show/Hide the Full List
mod site	chr1:109926177-109926178:+		[4]
Sequence	CTCAGAGAGAGTACAGTGGGACTGTTACCTTCCTTGATATG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000420111.6; ENST00000329608.11; ENST00000369802.7
External Link	RMBase: m6A_site_44231
mod ID: M6ASITE041453		Click to Show/Hide the Full List
mod site	chr1:109928864-109928865:+		[4]
Sequence	CCCACAGCTGGACGCACAGAACAGTCTCTCCGTGGGAGGAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; A549; GM12878; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44232
mod ID: M6ASITE041454		Click to Show/Hide the Full List
mod site	chr1:109928885-109928886:+		[4]
Sequence	CAGTCTCTCCGTGGGAGGAGACATTATGGGGCGTCCACCAC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; GM12878; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000420111.6; ENST00000329608.11
External Link	RMBase: m6A_site_44233
mod ID: M6ASITE041455		Click to Show/Hide the Full List
mod site	chr1:109928970-109928971:+		[4]
Sequence	CAGAGCTCCTGCCTGCCAGGACTGGACCAGAGCAGCCAGGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44234
mod ID: M6ASITE041456		Click to Show/Hide the Full List
mod site	chr1:109928975-109928976:+		[4]
Sequence	CTCCTGCCTGCCAGGACTGGACCAGAGCAGCCAGGCTGGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44235
mod ID: M6ASITE041457		Click to Show/Hide the Full List
mod site	chr1:109929009-109929010:+		[7]
Sequence	GCTGGGGCCCCTCTGTCTCAACCCGCAGACCCTTGACTGAA
Motif Score	2.153267857
Cell/Tissue List	CD8T; A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44236
mod ID: M6ASITE041458		Click to Show/Hide the Full List
mod site	chr1:109929017-109929018:+		[4]
Sequence	CCCTCTGTCTCAACCCGCAGACCCTTGACTGAATGAGAGAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44237
mod ID: M6ASITE041459		Click to Show/Hide the Full List
mod site	chr1:109929024-109929025:+		[7]
Sequence	TCTCAACCCGCAGACCCTTGACTGAATGAGAGAGGCCAGAG
Motif Score	3.28175
Cell/Tissue List	CD8T; A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000329608.11; ENST00000420111.6
External Link	RMBase: m6A_site_44238
mod ID: M6ASITE041460		Click to Show/Hide the Full List
mod site	chr1:109929127-109929128:+		[4]
Sequence	GCTGGTGAGCCCGGCTCAGGACCCTCTTCCCTCAGGGGCTG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44239
mod ID: M6ASITE041461		Click to Show/Hide the Full List
mod site	chr1:109929178-109929179:+		[4]
Sequence	TCACTCCCTTCCATGCCGGAACCCAGGCCAGGGACCCACCG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; CD8T; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44240
mod ID: M6ASITE041462		Click to Show/Hide the Full List
mod site	chr1:109929191-109929192:+		[4]
Sequence	TGCCGGAACCCAGGCCAGGGACCCACCGGCCTGTGGTTTGT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44241
mod ID: M6ASITE041463		Click to Show/Hide the Full List
mod site	chr1:109929227-109929228:+		[7]
Sequence	TTTGTGGGAAAGCAGGGTGGACGCTGAGGAGTGAAAGAACC
Motif Score	3.616982143
Cell/Tissue List	CD8T; A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44242
mod ID: M6ASITE041464		Click to Show/Hide the Full List
mod site	chr1:109929245-109929246:+		[4]
Sequence	GGACGCTGAGGAGTGAAAGAACCCTGCACCCAGAGGGCCTG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44243
mod ID: M6ASITE041465		Click to Show/Hide the Full List
mod site	chr1:109929292-109929293:+		[4]
Sequence	GCCAAGGTATCCCAGCCTGGACAGGCATGGACCTGTCTCCA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44244
mod ID: M6ASITE041466		Click to Show/Hide the Full List
mod site	chr1:109929302-109929303:+		[4]
Sequence	CCCAGCCTGGACAGGCATGGACCTGTCTCCAGAGAGAGGAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44245
mod ID: M6ASITE041467		Click to Show/Hide the Full List
mod site	chr1:109929343-109929344:+		[4]
Sequence	CCTGAAGTTCGTGGGGCGGGACAGCGTCGGCCTGATTTCCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44246
mod ID: M6ASITE041468		Click to Show/Hide the Full List
mod site	chr1:109929386-109929387:+		[7]
Sequence	AAAGGTGTGCAGCCTGAGAGACGGGAAGAGGAGGCCTCTGG
Motif Score	2.871321429
Cell/Tissue List	CD8T
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44247
mod ID: M6ASITE041469		Click to Show/Hide the Full List
mod site	chr1:109929407-109929408:+		[4]
Sequence	CGGGAAGAGGAGGCCTCTGGACCTGCTGGTCTGCACTGACA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44248
mod ID: M6ASITE041470		Click to Show/Hide the Full List
mod site	chr1:109929512-109929513:+		[4]
Sequence	AGGCCAGCCCTGCCCTCAGGACCTGCCTGACCTGCCAGTGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44249
mod ID: M6ASITE041471		Click to Show/Hide the Full List
mod site	chr1:109929648-109929649:+		[4]
Sequence	AGGAAGCCATTGCACTGTGAACACTGTACCTGCCTGCTGAA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hESCs; fibroblasts; GM12878; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44250
mod ID: M6ASITE041472		Click to Show/Hide the Full List
mod site	chr1:109929668-109929669:+		[4]
Sequence	ACACTGTACCTGCCTGCTGAACAGCCTGCCCCCGTCCATCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hESCs; fibroblasts; GM12878; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44251
mod ID: M6ASITE041473		Click to Show/Hide the Full List
mod site	chr1:109929838-109929839:+		[4]
Sequence	GAGTGGAGTGGGGTGGGAGAACCTCCTGGGCCGCCAGCCAG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44252
mod ID: M6ASITE041474		Click to Show/Hide the Full List
mod site	chr1:109929931-109929932:+		[4]
Sequence	ACATTCCCAAGAGGGAAGGGACTAGTGGGAGAGAGCAAGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hESCs; fibroblasts; LCLs; Huh7; Jurkat; CD4T; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44253
mod ID: M6ASITE041475		Click to Show/Hide the Full List
mod site	chr1:109929966-109929967:+		[4]
Sequence	CAAGGGAGGGGAGGGCACAGACAGAGAGGCTACAGGGCGAG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hNPCs; hESCs; fibroblasts; LCLs; Huh7; Jurkat; CD4T; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44254
mod ID: M6ASITE041476		Click to Show/Hide the Full List
mod site	chr1:109930056-109930057:+		[4]
Sequence	GGGAGGGTCTGCACTCCCAAACCCCAGCGCAGTGTCCTTTC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; A549; U2OS; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44255
mod ID: M6ASITE041477		Click to Show/Hide the Full List
mod site	chr1:109930093-109930094:+		[4]
Sequence	TTTCCCTGCTGCCGACAGGAACCTGGGGCTGAACAGGTTAT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; Huh7; HEK293A-TOA; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44256
mod ID: M6ASITE041478		Click to Show/Hide the Full List
mod site	chr1:109930105-109930106:+		[4]
Sequence	CGACAGGAACCTGGGGCTGAACAGGTTATCCCTGTCAGGAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; Huh7; HEK293A-TOA; iSLK; MSC; TIME; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44257
mod ID: M6ASITE041479		Click to Show/Hide the Full List
mod site	chr1:109930132-109930133:+		[4]
Sequence	ATCCCTGTCAGGAGCCCTGGACTGGGCTGCATCTCAGCCCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; Huh7; HEK293A-TOA; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44258
mod ID: M6ASITE041480		Click to Show/Hide the Full List
mod site	chr1:109930460-109930461:+		[4]
Sequence	CCTTTGTCCTCCGCTAAGAGACCCTGCCCTACCTGGCCGCT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44259
mod ID: M6ASITE041481		Click to Show/Hide the Full List
mod site	chr1:109930576-109930577:+		[8]
Sequence	AGCTTAGGGAAGGGCAGTGAACTTGCATATGGGGCTTAGCC
Motif Score	3.373380952
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44260
mod ID: M6ASITE041482		Click to Show/Hide the Full List
mod site	chr1:109930631-109930632:+		[9]
Sequence	TCTATATTTGATGCTAGAAAACACATATTTTTAAATGGAAG
Motif Score	2.20572619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44261
mod ID: M6ASITE041483		Click to Show/Hide the Full List
mod site	chr1:109930823-109930824:+		[4]
Sequence	CCCAGGCTACCTGCTCAGGAACCCCTTCTGTTCTCTGAGAA
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44262
mod ID: M6ASITE041484		Click to Show/Hide the Full List
mod site	chr1:109930855-109930856:+		[4]
Sequence	CTCTGAGAAGTCAAGAGAGGACATTGGCTCACGCACTGTGA
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000329608.11
External Link	RMBase: m6A_site_44263

Ref 1	WO patent application no. 2014,1441,21, Classification and actionability indices for lung cancer.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 Apr 10;31(4):591-606.e6. doi: 10.1016/j.ccell.2017.02.013. Epub 2017 Mar 23.
Ref 6	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 7	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 8	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 9	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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