m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01023)

Target Name	long intergenic non-protein coding RNA 839 (LINC00839)
Gene Name	LINC00839
Chromosomal Location	10q11.21
Gene ID	84856
HGNC ID	HGNC:28269

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Protein virilizer homolog (VIRMA)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05740		Crosstalk Info
Epigenetic Regulator	Long intergenic non-protein coding RNA 839 (LINC00839)
Regulated Target	TATA-box binding protein associated factor 15 (TAF15)
Crosstalk relationship	m6A → ncRNA
Disease	Nasopharyngeal carcinoma	Disease Info

m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05741		Crosstalk Info
Epigenetic Regulator	Long intergenic non-protein coding RNA 839 (LINC00839)
Regulated Target	TATA-box binding protein associated factor 15 (TAF15)
Crosstalk relationship	m6A → ncRNA
Disease	Nasopharyngeal carcinoma	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01023)

long intergenic non-protein coding RNA 839 (LINC00839)

N6-methyladenosine (m6A)

In total 22 m6A sequence/site(s) in this target gene
mod ID: M6ASITE096350		Click to Show/Hide the Full List
mod site	chr10:42475682-42475683:+		[2]
Sequence	GCAGGAGGAGAAGGAAGAGAACTGGGTGCCGCCTGCCTGCA
Motif Score	3.373380952
Cell/Tissue List	HEK293A-TOA; iSLK; TREX; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000429940.6; ENST00000424751.2
External Link	RMBase: m6A_site_98600
mod ID: M6ASITE096351		Click to Show/Hide the Full List
mod site	chr10:42475816-42475817:+		[3]
Sequence	CCGCTGCGCCTCCTCCCAGAACCCAAGAAGCCTGGAACCTG
Motif Score	2.930744048
Cell/Tissue List	GSCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98601
mod ID: M6ASITE096352		Click to Show/Hide the Full List
mod site	chr10:42475832-42475833:+		[3]
Sequence	CAGAACCCAAGAAGCCTGGAACCTGTGGCGTCCAGCCCTGA
Motif Score	2.930744048
Cell/Tissue List	GSCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98602
mod ID: M6ASITE096353		Click to Show/Hide the Full List
mod site	chr10:42475919-42475920:+		[2]
Sequence	ATACCGGCGGCAGAGGAAGGACAGGCAGGAGTCTCGGCCTC
Motif Score	3.643047619
Cell/Tissue List	HEK293A-TOA; GSCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000429940.6; ENST00000424751.2
External Link	RMBase: m6A_site_98603
mod ID: M6ASITE096354		Click to Show/Hide the Full List
mod site	chr10:42492173-42492174:+		[4]
Sequence	ATTTTGGGAAGAACCCAAGGACCCCCCAGTTGCAGCCATGT
Motif Score	3.622404762
Cell/Tissue List	fibroblasts; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3289523; ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98604
mod ID: M6ASITE096355		Click to Show/Hide the Full List
mod site	chr10:42492198-42492199:+		[4]
Sequence	CCAGTTGCAGCCATGTCAAGACTGACAATAAGGAAGACATC
Motif Score	3.319380952
Cell/Tissue List	fibroblasts; Huh7; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000429940.6; ENST00000424751.2; rmsk_3289523
External Link	RMBase: m6A_site_98605
mod ID: M6ASITE096356		Click to Show/Hide the Full List
mod site	chr10:42492214-42492215:+		[4]
Sequence	CAAGACTGACAATAAGGAAGACATCAGTCCCAGCAAGCAAC
Motif Score	2.897386905
Cell/Tissue List	fibroblasts; Huh7; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000429940.6; ENST00000424751.2; rmsk_3289523
External Link	RMBase: m6A_site_98606
mod ID: M6ASITE096357		Click to Show/Hide the Full List
mod site	chr10:42492324-42492325:+		[5]
Sequence	AAGAAAGCGGATGACCAGCTACAATGAGTAATCTAATGGTA
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000424751.2; ENST00000429940.6; rmsk_3289523
External Link	RMBase: m6A_site_98607
mod ID: M6ASITE096358		Click to Show/Hide the Full List
mod site	chr10:42494093-42494094:+		[6]
Sequence	GCTTTTATCGCTTTGCAAAAACAGAAAAGGGGACATGCTGG
Motif Score	2.20572619
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000429940.6; rmsk_3289523; ENST00000424751.2
External Link	RMBase: m6A_site_98608
mod ID: M6ASITE096359		Click to Show/Hide the Full List
mod site	chr10:42494105-42494106:+		[6]
Sequence	TTGCAAAAACAGAAAAGGGGACATGCTGGGAACAGGCCCTA
Motif Score	3.643047619
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000424751.2; ENST00000429940.6; rmsk_3289523
External Link	RMBase: m6A_site_98609
mod ID: M6ASITE096360		Click to Show/Hide the Full List
mod site	chr10:42494116-42494117:+		[6]
Sequence	GAAAAGGGGACATGCTGGGAACAGGCCCTAAGCCTGTCATA
Motif Score	2.951386905
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	rmsk_3289524; ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98610
mod ID: M6ASITE096361		Click to Show/Hide the Full List
mod site	chr10:42494138-42494139:+		[6]
Sequence	AGGCCCTAAGCCTGTCATAAACAGGCCTTAAACTGACCATG
Motif Score	2.20572619
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000424751.2; ENST00000429940.6; rmsk_3289524
External Link	RMBase: m6A_site_98611
mod ID: M6ASITE096362		Click to Show/Hide the Full List
mod site	chr10:42494149-42494150:+		[6]
Sequence	CTGTCATAAACAGGCCTTAAACTGACCATGAACAGGATTTC
Motif Score	2.627720238
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	rmsk_3289524; ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98612
mod ID: M6ASITE096363		Click to Show/Hide the Full List
mod site	chr10:42494160-42494161:+		[6]
Sequence	AGGCCTTAAACTGACCATGAACAGGATTTCTGCACGAATGT
Motif Score	2.951386905
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000429940.6; rmsk_3289524; ENST00000424751.2
External Link	RMBase: m6A_site_98613
mod ID: M6ASITE096364		Click to Show/Hide the Full List
mod site	chr10:42494247-42494248:+		[6]
Sequence	TTACTGGAGCAGGGTAGGGAACACCTGGCCCACCCGGAGCG
Motif Score	2.951386905
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000424751.2; rmsk_3289524; ENST00000429940.6
External Link	RMBase: m6A_site_98614
mod ID: M6ASITE096365		Click to Show/Hide the Full List
mod site	chr10:42494272-42494273:+		[6]
Sequence	TGGCCCACCCGGAGCGGAAAACTGCTCAAACCACAAACAAC
Motif Score	2.627720238
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000429940.6; ENST00000424751.2; rmsk_3289524
External Link	RMBase: m6A_site_98615
mod ID: M6ASITE096366		Click to Show/Hide the Full List
mod site	chr10:42494281-42494282:+		[6]
Sequence	CGGAGCGGAAAACTGCTCAAACCACAAACAACAGCATGAGT
Motif Score	2.185083333
Cell/Tissue List	HEK293T; U2OS; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	rmsk_3289524; ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98616
mod ID: M6ASITE096367		Click to Show/Hide the Full List
mod site	chr10:42494288-42494289:+		[4]
Sequence	GAAAACTGCTCAAACCACAAACAACAGCATGAGTGGCCTGA
Motif Score	2.20572619
Cell/Tissue List	HEK293T; fibroblasts; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000424751.2; rmsk_3289524; ENST00000429940.6
External Link	RMBase: m6A_site_98617
mod ID: M6ASITE096368		Click to Show/Hide the Full List
mod site	chr10:42494349-42494350:+		[2]
Sequence	CTGCAGATAATCGGCCAGAGACTGTTTCTCTACTCCTCTCT
Motif Score	3.319380952
Cell/Tissue List	HEK293T; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000429940.6; ENST00000424751.2; rmsk_3289524
External Link	RMBase: m6A_site_98618
mod ID: M6ASITE096369		Click to Show/Hide the Full List
mod site	chr10:42494425-42494426:+		[7]
Sequence	CTAATCTGTAACCTATAGAAACAATGCTTATCACTGGCTTG
Motif Score	2.20572619
Cell/Tissue List	H1299; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3289524; ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98619
mod ID: M6ASITE096370		Click to Show/Hide the Full List
mod site	chr10:42494456-42494457:+		[8]
Sequence	CACTGGCTTGCTGTCAATAAACATGTGGGTCAAACTCTGTT
Motif Score	2.20572619
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_3289524; ENST00000424751.2; ENST00000429940.6
External Link	RMBase: m6A_site_98620
mod ID: M6ASITE096371		Click to Show/Hide the Full List
mod site	chr10:42494469-42494470:+		[8]
Sequence	TCAATAAACATGTGGGTCAAACTCTGTTTGTGGCTCTCAGC
Motif Score	2.627720238
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000424751.2; ENST00000429940.6; rmsk_3289524
External Link	RMBase: m6A_site_98621

Ref 1	Clinical pipeline report, company report or official report of AbbVie.
Ref 2	The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003.
Ref 3	m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 Mar 14;18(11):2622-2634. doi: 10.1016/j.celrep.2017.02.059.
Ref 4	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 5	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 6	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 7	The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016 May 5;62(3):335-345. doi: 10.1016/j.molcel.2016.03.021. Epub 2016 Apr 21.
Ref 8	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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