m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00484)
Target Name Cystine/glutamate transporter (SLC7A11)
Synonyms
Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT
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Gene Name SLC7A11
Chromosomal Location 4q28.3
Family amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. {ECO:0000305}.
Function
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. {ECO:0000269|PubMed:15151999}.
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Gene ID 55083
Uniprot ID
XCT_HUMAN
HGNC ID
HGNC:11059
KEGG ID
hsa:23657
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
SLC7A11 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) [READER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by IGF2BP1
Cell Line MV3 cell line Homo sapiens
Treatment: siIGF2BP1 MV3 cells
Control: siControl MV3 cells
 GSE146803
Regulation
logFC: -1.30E+00
p-value: 3.62E-06
More Results Click to View More RNA-seq Results
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary METTL3-mediated Cystine/glutamate transporter (SLC7A11) m6A modification enhances hepatoblastoma ferroptosis resistance. The METTL3/IGF2BP1/m6A modification promotes SLC7A11 mRNA stability and upregulates its expression by inhibiting the deadenylation process.
Target Regulation Up regulation
Responsed Disease Hepatoblastoma ICD-11: 2C12.01
 Disease Info 
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model HuH-6 Hepatoblastoma Homo sapiens CVCL_4381
Hep-G2 Hepatoblastoma Homo sapiens CVCL_0027
HEK293T Normal Homo sapiens CVCL_0063
Methyltransferase-like 14 (METTL14) [WRITER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by METTL14
Cell Line HepG2 cell line Homo sapiens
Treatment: shMETTL14 HepG2 cells
Control: shCtrl HepG2 cells
 GSE121949
Regulation
logFC: -1.11E+00
p-value: 3.96E-11
More Results Click to View More RNA-seq Results
In total 4 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [2]
Response Summary METTL14 induced m6A modification at 5'UTR of Cystine/glutamate transporter (SLC7A11) mRNA, which in turn underwent degradation relied on the YTHDF2-dependent pathway. Identify the HIF-1alpha /METTL14/YTHDF2/SLC7A11 axis as a potential therapeutic target for the HCC interventional embolization treatment.
Target Regulation Down regulation
Responsed Disease Liver cancer ICD-11: 2C12
 Disease Info 
Pathway Response HIF-1 signaling pathway hsa04066
Cell Process RNA stability
In-vitro Model PLC/PRF/5 Adult hepatocellular carcinoma Homo sapiens CVCL_0485
MHCC97-H Adult hepatocellular carcinoma Homo sapiens CVCL_4972
L-02 Endocervical adenocarcinoma Homo sapiens CVCL_6926
Huh-7 Adult hepatocellular carcinoma Homo sapiens CVCL_0336
Hep-G2 Hepatoblastoma Homo sapiens CVCL_0027
HCCLM3 Adult hepatocellular carcinoma Homo sapiens CVCL_6832
BEL-7402 Endocervical adenocarcinoma Homo sapiens CVCL_5492
7721 (Human hepatic malignant cell line)
In-vivo Model For the subcutaneous implantation model, 5 × 105 stable SLC7A11-knockdown HCCLM3 cells or SLC7A11-vector cells were injected subcutaneously into BALB/C nude mice.
Experiment 2 Reporting the m6A Methylation Regulator of This Target Gene [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Responsed Drug Pertuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 3 Reporting the m6A Methylation Regulator of This Target Gene [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Responsed Drug Trastuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 4 Reporting the m6A Methylation Regulator of This Target Gene [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Responsed Drug Tucatinib Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Methyltransferase-like 3 (METTL3) [WRITER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by METTL3
Cell Line MOLM-13 cell line Homo sapiens
Treatment: shMETTL3 MOLM13 cells
Control: MOLM13 cells
 GSE98623
Regulation
logFC: -4.02E+00
p-value: 2.26E-108
More Results Click to View More RNA-seq Results
In total 2 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary METTL3-mediated Cystine/glutamate transporter (SLC7A11) m6A modification enhances hepatoblastoma ferroptosis resistance. The METTL3/IGF2BP1/m6A modification promotes SLC7A11 mRNA stability and upregulates its expression by inhibiting the deadenylation process.
Target Regulation Up regulation
Responsed Disease Hepatoblastoma ICD-11: 2C12.01
 Disease Info 
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model HuH-6 Hepatoblastoma Homo sapiens CVCL_4381
Hep-G2 Hepatoblastoma Homo sapiens CVCL_0027
HEK293T Normal Homo sapiens CVCL_0063
Experiment 2 Reporting the m6A Methylation Regulator of This Target Gene [4]
Response Summary METTL3-mediated m-6A modification could stabilize Cystine/glutamate transporter (SLC7A11) mRNA and promote its translation, thus promoting LUAD cell proliferation and inhibiting cell ferroptosis, a novel form of programmed cell death.
Target Regulation Up regulation
Responsed Disease Lung adenocarcinoma ICD-11: 2C25.0
 Disease Info 
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model SPC-A1 Endocervical adenocarcinoma Homo sapiens CVCL_6955
PC-9 Lung adenocarcinoma Homo sapiens CVCL_B260
NCI-H460 Lung large cell carcinoma Homo sapiens CVCL_0459
NCI-H322 Minimally invasive lung adenocarcinoma Homo sapiens CVCL_1556
NCI-H1975 Lung adenocarcinoma Homo sapiens CVCL_1511
NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
BEAS-2B Normal Homo sapiens CVCL_0168
A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
In-vivo Model For the subcutaneous xenograft model, PC9 cells stably transfected with METTL3 knockdown (shMETTL3) or negative control (shNC) shRNA (5 × 106 cells per mouse, n = 6) were suspended in 200 uL PBS with 50% Matrigel matrix (Corning, USA, 354234) and then injected into one side of the axilla of nude mice.
NF-kappa-B-activating protein (NKAP) [READER]
 Regulator Info 
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [9]
Response Summary This study NKAP knockdown induced cell death in glioblastoma cells. NKAP acted as a new ferroptosis suppressor by binding to m6A and then promoting Cystine/glutamate transporter (SLC7A11) mRNA splicing and maturation.
Target Regulation Up regulation
Responsed Disease Glioblastoma ICD-11: 2A00.00
 Disease Info 
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model U87MG (Astroblastoma cells from human brain)
U251 (Fibroblasts or fibroblast like cells)
In-vivo Model The male BALB/c nude mice were randomized divide into two groups, each group including six 4 weeks old nude mice. Investigators were blinded to the treatment groups during data collection and subsequent data analysis. In the subcutaneous xenograft model, 5 × 105 cells were subcutaneously injected in the right flanks of nude mice. In the orthotopic intracranial mouse model, each mouse was intracranially injected with 1 × 105 luciferase transfected U87MG cells in 10 uL PBS solution.
YTH domain-containing protein 2 (YTHDC2) [READER]
 Regulator Info 
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [14]
Response Summary YTHDC2 destabilized Cystine/glutamate transporter (SLC7A11) mRNA in an m6A-dependent manner because YTHDC2 preferentially bound to m6A-modified SLC7A11 mRNA and thereafter promoted its decay. the promotion of cystine uptake via the suppression of YTHDC2 is critical for LUAD tumorigenesis.
Target Regulation Down regulation
Responsed Disease Lung adenocarcinoma ICD-11: 2C25.0
 Disease Info 
In-vitro Model PC-9 Lung adenocarcinoma Homo sapiens CVCL_B260
NCI-H441 Lung papillary adenocarcinoma Homo sapiens CVCL_1561
NCI-H292 Lung mucoepidermoid carcinoma Homo sapiens CVCL_0455
NCI-H1975 Lung adenocarcinoma Homo sapiens CVCL_1511
NCI-H1650 Minimally invasive lung adenocarcinoma Homo sapiens CVCL_1483
NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
HEK293T Normal Homo sapiens CVCL_0063
HCC827 Lung adenocarcinoma Homo sapiens CVCL_2063
Calu-1 Lung squamous cell carcinoma Homo sapiens CVCL_0608
BEAS-2B Normal Homo sapiens CVCL_0168
A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
Brain cancer [ICD-11: 2A00]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [9]
Response Summary This study NKAP knockdown induced cell death in glioblastoma cells. NKAP acted as a new ferroptosis suppressor by binding to m6A and then promoting Cystine/glutamate transporter (SLC7A11) mRNA splicing and maturation.
Responsed Disease Glioblastoma [ICD-11: 2A00.00]
Target Regulator NF-kappa-B-activating protein (NKAP) READER
 Regulator Info 
Target Regulation Up regulation
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model U87MG (Astroblastoma cells from human brain)
U251 (Fibroblasts or fibroblast like cells)
In-vivo Model The male BALB/c nude mice were randomized divide into two groups, each group including six 4 weeks old nude mice. Investigators were blinded to the treatment groups during data collection and subsequent data analysis. In the subcutaneous xenograft model, 5 × 105 cells were subcutaneously injected in the right flanks of nude mice. In the orthotopic intracranial mouse model, each mouse was intracranially injected with 1 × 105 luciferase transfected U87MG cells in 10 uL PBS solution.
Liver cancer [ICD-11: 2C12]
 Disease Info 
In total 3 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary METTL3-mediated Cystine/glutamate transporter (SLC7A11) m6A modification enhances hepatoblastoma ferroptosis resistance. The METTL3/IGF2BP1/m6A modification promotes SLC7A11 mRNA stability and upregulates its expression by inhibiting the deadenylation process.
Responsed Disease Hepatoblastoma [ICD-11: 2C12.01]
Target Regulator Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) READER
 Regulator Info 
Target Regulation Up regulation
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model HuH-6 Hepatoblastoma Homo sapiens CVCL_4381
Hep-G2 Hepatoblastoma Homo sapiens CVCL_0027
HEK293T Normal Homo sapiens CVCL_0063
Experiment 2 Reporting the m6A-centered Disease Response [2]
Response Summary METTL14 induced m6A modification at 5'UTR of Cystine/glutamate transporter (SLC7A11) mRNA, which in turn underwent degradation relied on the YTHDF2-dependent pathway. Identify the HIF-1alpha /METTL14/YTHDF2/SLC7A11 axis as a potential therapeutic target for the HCC interventional embolization treatment.
Responsed Disease Liver cancer [ICD-11: 2C12]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Pathway Response HIF-1 signaling pathway hsa04066
Cell Process RNA stability
In-vitro Model PLC/PRF/5 Adult hepatocellular carcinoma Homo sapiens CVCL_0485
MHCC97-H Adult hepatocellular carcinoma Homo sapiens CVCL_4972
L-02 Endocervical adenocarcinoma Homo sapiens CVCL_6926
Huh-7 Adult hepatocellular carcinoma Homo sapiens CVCL_0336
Hep-G2 Hepatoblastoma Homo sapiens CVCL_0027
HCCLM3 Adult hepatocellular carcinoma Homo sapiens CVCL_6832
BEL-7402 Endocervical adenocarcinoma Homo sapiens CVCL_5492
7721 (Human hepatic malignant cell line)
In-vivo Model For the subcutaneous implantation model, 5 × 105 stable SLC7A11-knockdown HCCLM3 cells or SLC7A11-vector cells were injected subcutaneously into BALB/C nude mice.
Experiment 3 Reporting the m6A-centered Disease Response [1]
Response Summary METTL3-mediated Cystine/glutamate transporter (SLC7A11) m6A modification enhances hepatoblastoma ferroptosis resistance. The METTL3/IGF2BP1/m6A modification promotes SLC7A11 mRNA stability and upregulates its expression by inhibiting the deadenylation process.
Responsed Disease Hepatoblastoma [ICD-11: 2C12.01]
Target Regulator Methyltransferase-like 3 (METTL3) WRITER
 Regulator Info 
Target Regulation Up regulation
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model HuH-6 Hepatoblastoma Homo sapiens CVCL_4381
Hep-G2 Hepatoblastoma Homo sapiens CVCL_0027
HEK293T Normal Homo sapiens CVCL_0063
Lung cancer [ICD-11: 2C25]
 Disease Info 
In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [4]
Response Summary METTL3-mediated m-6A modification could stabilize Cystine/glutamate transporter (SLC7A11) mRNA and promote its translation, thus promoting LUAD cell proliferation and inhibiting cell ferroptosis, a novel form of programmed cell death.
Responsed Disease Lung adenocarcinoma [ICD-11: 2C25.0]
Target Regulator Methyltransferase-like 3 (METTL3) WRITER
 Regulator Info 
Target Regulation Up regulation
Pathway Response Ferroptosis hsa04216
Cell Process Ferroptosis
In-vitro Model SPC-A1 Endocervical adenocarcinoma Homo sapiens CVCL_6955
PC-9 Lung adenocarcinoma Homo sapiens CVCL_B260
NCI-H460 Lung large cell carcinoma Homo sapiens CVCL_0459
NCI-H322 Minimally invasive lung adenocarcinoma Homo sapiens CVCL_1556
NCI-H1975 Lung adenocarcinoma Homo sapiens CVCL_1511
NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
BEAS-2B Normal Homo sapiens CVCL_0168
A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
In-vivo Model For the subcutaneous xenograft model, PC9 cells stably transfected with METTL3 knockdown (shMETTL3) or negative control (shNC) shRNA (5 × 106 cells per mouse, n = 6) were suspended in 200 uL PBS with 50% Matrigel matrix (Corning, USA, 354234) and then injected into one side of the axilla of nude mice.
Experiment 2 Reporting the m6A-centered Disease Response [14]
Response Summary YTHDC2 destabilized Cystine/glutamate transporter (SLC7A11) mRNA in an m6A-dependent manner because YTHDC2 preferentially bound to m6A-modified SLC7A11 mRNA and thereafter promoted its decay. the promotion of cystine uptake via the suppression of YTHDC2 is critical for LUAD tumorigenesis.
Responsed Disease Lung adenocarcinoma [ICD-11: 2C25.0]
Target Regulator YTH domain-containing protein 2 (YTHDC2) READER
 Regulator Info 
Target Regulation Down regulation
In-vitro Model PC-9 Lung adenocarcinoma Homo sapiens CVCL_B260
NCI-H441 Lung papillary adenocarcinoma Homo sapiens CVCL_1561
NCI-H292 Lung mucoepidermoid carcinoma Homo sapiens CVCL_0455
NCI-H1975 Lung adenocarcinoma Homo sapiens CVCL_1511
NCI-H1650 Minimally invasive lung adenocarcinoma Homo sapiens CVCL_1483
NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
HEK293T Normal Homo sapiens CVCL_0063
HCC827 Lung adenocarcinoma Homo sapiens CVCL_2063
Calu-1 Lung squamous cell carcinoma Homo sapiens CVCL_0608
BEAS-2B Normal Homo sapiens CVCL_0168
A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
Breast cancer [ICD-11: 2C60]
 Disease Info 
In total 3 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Responsed Disease Breast cancer [ICD-11: 2C60]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Drug Pertuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 2 Reporting the m6A-centered Disease Response [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Responsed Disease Breast cancer [ICD-11: 2C60]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Drug Trastuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 3 Reporting the m6A-centered Disease Response [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Responsed Disease Breast cancer [ICD-11: 2C60]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Drug Tucatinib Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Pertuzumab [Approved]
 Drug Info 
In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Trastuzumab [Approved]
 Drug Info 
In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Tucatinib [Approved]
 Drug Info 
In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response [3]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates GSK-3beta and activates beta-catenin/TCF4-Cystine/glutamate transporter (SLC7A11)/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
DNA modification
m6A Regulator: Methyltransferase-like 14 (METTL14)
 Regulator Info 
In total 9 item(s) under this m6A regulator
Crosstalk ID: M6ACROT02207
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 3B (DNMT3B)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Trastuzumab
 Drug Info 
Crosstalk ID: M6ACROT02212
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 3B (DNMT3B)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Pertuzumab
 Drug Info 
Crosstalk ID: M6ACROT02220
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 3B (DNMT3B)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Tucatinib
 Drug Info 
Crosstalk ID: M6ACROT02231
 Crosstalk Info 
Epigenetic Regulator Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Trastuzumab
 Drug Info 
Crosstalk ID: M6ACROT02236
 Crosstalk Info 
Epigenetic Regulator Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Pertuzumab
 Drug Info 
Crosstalk ID: M6ACROT02244
 Crosstalk Info 
Epigenetic Regulator Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Tucatinib
 Drug Info 
Crosstalk ID: M6ACROT02255
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Trastuzumab
 Drug Info 
Crosstalk ID: M6ACROT02260
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Pertuzumab
 Drug Info 
Crosstalk ID: M6ACROT02268
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Tucatinib
 Drug Info 
Histone modification
m6A Regulator: RNA demethylase ALKBH5 (ALKBH5)
 Regulator Info 
In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03360
 Crosstalk Info 
Epigenetic Regulator Histone deacetylase 2 (HDAC2)
Regulated Target Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
 Disease Info 
Crosstalk ID: M6ACROT03456
 Crosstalk Info 
Epigenetic Regulator Histone deacetylase 1 (HDAC1)
Regulated Target Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
 Disease Info 
Non-coding RNA
m6A Regulator: Methyltransferase-like 3 (METTL3)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05054
 Crosstalk Info 
Epigenetic Regulator MicroRNA 186 (MIR186)
Regulated Target Methyltransferase-like protein 3 (METTL3)
Crosstalk relationship ncRNA → m6A
Disease Hepatoblastoma
 Disease Info 
m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05273
 Crosstalk Info 
Epigenetic Regulator Long intergenic non-protein coding RNA 942 (LINC00942)
Regulated Target Insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3)
Crosstalk relationship ncRNA → m6A
Disease Liver cancer
 Disease Info 
m6A Regulator: Staphylococcal nuclease domain-containing protein 1 (SND1)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05311
 Crosstalk Info 
Epigenetic Regulator Small nucleolar RNA host gene 1 (SNHG1)
Regulated Target Staphylococcal nuclease domain-containing protein 1 (SND1)
Crosstalk relationship ncRNA → m6A
Disease Liver cancer
 Disease Info 
Drug Sorafenib
 Drug Info 
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00484)
Cystine/glutamate transporter (SLC7A11)
Adenosine-to-Inosine editing (A-to-I)
In total 33 m6A sequence/site(s) in this target gene
mod ID: A2ISITE000538 Click to Show/Hide the Full List
mod site chr4:138188216-138188217:- [15]
Sequence TAAAAAAATTAGCTGGGTATAGTGATGGGTGCCTATAATCC
Transcript ID List ENST00000280612.9; ENST00000509248.1; rmsk_1451296
External Link RMBase: RNA-editing_site_106610
mod ID: A2ISITE000539 Click to Show/Hide the Full List
mod site chr4:138192339-138192340:- [16]
Sequence CAACTAGCTCACTCAGGAAAAGAATGTCACAAGGTGACACA
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106611
mod ID: A2ISITE000540 Click to Show/Hide the Full List
mod site chr4:138196696-138196697:- [17]
Sequence ATTGCACTCCCGCCCGGGTGACAAGAGTGAGGCTCTGTCTA
Transcript ID List ENST00000280612.9; ENST00000509248.1; rmsk_1451306
External Link RMBase: RNA-editing_site_106612
mod ID: A2ISITE000541 Click to Show/Hide the Full List
mod site chr4:138196731-138196732:- [17]
Sequence AGGAGGTGAAGGTTGCAGTGAGCCGAGATTGTGCCATTGCA
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106613
mod ID: A2ISITE000542 Click to Show/Hide the Full List
mod site chr4:138196742-138196743:- [17]
Sequence TGCCTGAACCCAGGAGGTGAAGGTTGCAGTGAGCCGAGATT
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106614
mod ID: A2ISITE000543 Click to Show/Hide the Full List
mod site chr4:138196751-138196752:- [17]
Sequence CAGAAGAATTGCCTGAACCCAGGAGGTGAAGGTTGCAGTGA
Transcript ID List ENST00000280612.9; rmsk_1451306; ENST00000509248.1
External Link RMBase: RNA-editing_site_106615
mod ID: A2ISITE000544 Click to Show/Hide the Full List
mod site chr4:138196755-138196756:- [17]
Sequence GAAGCAGAAGAATTGCCTGAACCCAGGAGGTGAAGGTTGCA
Transcript ID List rmsk_1451306; ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106616
mod ID: A2ISITE000545 Click to Show/Hide the Full List
mod site chr4:138196764-138196765:- [17]
Sequence CGGGAGGCTGAAGCAGAAGAATTGCCTGAACCCAGGAGGTG
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106617
mod ID: A2ISITE000546 Click to Show/Hide the Full List
mod site chr4:138196765-138196766:- [17]
Sequence TCGGGAGGCTGAAGCAGAAGAATTGCCTGAACCCAGGAGGT
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106618
mod ID: A2ISITE000547 Click to Show/Hide the Full List
mod site chr4:138196767-138196768:- [17]
Sequence ACTCGGGAGGCTGAAGCAGAAGAATTGCCTGAACCCAGGAG
Transcript ID List ENST00000509248.1; ENST00000280612.9; rmsk_1451306
External Link RMBase: RNA-editing_site_106619
mod ID: A2ISITE000549 Click to Show/Hide the Full List
mod site chr4:138196768-138196769:- [17]
Sequence TACTCGGGAGGCTGAAGCAGAAGAATTGCCTGAACCCAGGA
Transcript ID List rmsk_1451306; ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106620
mod ID: A2ISITE000550 Click to Show/Hide the Full List
mod site chr4:138196770-138196771:- [17]
Sequence GCTACTCGGGAGGCTGAAGCAGAAGAATTGCCTGAACCCAG
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106621
mod ID: A2ISITE000551 Click to Show/Hide the Full List
mod site chr4:138196773-138196774:- [17]
Sequence CCAGCTACTCGGGAGGCTGAAGCAGAAGAATTGCCTGAACC
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106622
mod ID: A2ISITE000552 Click to Show/Hide the Full List
mod site chr4:138196780-138196781:- [17]
Sequence TGTAATCCCAGCTACTCGGGAGGCTGAAGCAGAAGAATTGC
Transcript ID List rmsk_1451306; ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106623
mod ID: A2ISITE000553 Click to Show/Hide the Full List
mod site chr4:138196787-138196788:- [17]
Sequence AGTTGCCTGTAATCCCAGCTACTCGGGAGGCTGAAGCAGAA
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106624
mod ID: A2ISITE000554 Click to Show/Hide the Full List
mod site chr4:138196791-138196792:- [17]
Sequence TGGCAGTTGCCTGTAATCCCAGCTACTCGGGAGGCTGAAGC
Transcript ID List ENST00000280612.9; ENST00000509248.1; rmsk_1451306
External Link RMBase: RNA-editing_site_106625
mod ID: A2ISITE000555 Click to Show/Hide the Full List
mod site chr4:138196796-138196797:- [17]
Sequence TGTGGTGGCAGTTGCCTGTAATCCCAGCTACTCGGGAGGCT
Transcript ID List rmsk_1451306; ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106626
mod ID: A2ISITE000556 Click to Show/Hide the Full List
mod site chr4:138196797-138196798:- [17]
Sequence GTGTGGTGGCAGTTGCCTGTAATCCCAGCTACTCGGGAGGC
Transcript ID List ENST00000280612.9; ENST00000509248.1; rmsk_1451306
External Link RMBase: RNA-editing_site_106627
mod ID: A2ISITE000557 Click to Show/Hide the Full List
mod site chr4:138196807-138196808:- [17]
Sequence AATAAGCTGAGTGTGGTGGCAGTTGCCTGTAATCCCAGCTA
Transcript ID List ENST00000509248.1; rmsk_1451306; ENST00000280612.9
External Link RMBase: RNA-editing_site_106628
mod ID: A2ISITE000558 Click to Show/Hide the Full List
mod site chr4:138196827-138196828:- [17]
Sequence GTCTCTACTAAAAATACAAAAATAAGCTGAGTGTGGTGGCA
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106629
mod ID: A2ISITE000560 Click to Show/Hide the Full List
mod site chr4:138196828-138196829:- [17]
Sequence TGTCTCTACTAAAAATACAAAAATAAGCTGAGTGTGGTGGC
Transcript ID List rmsk_1451306; ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106630
mod ID: A2ISITE000561 Click to Show/Hide the Full List
mod site chr4:138196832-138196833:- [17]
Sequence ACCCTGTCTCTACTAAAAATACAAAAATAAGCTGAGTGTGG
Transcript ID List ENST00000509248.1; ENST00000280612.9; rmsk_1451306
External Link RMBase: RNA-editing_site_106631
mod ID: A2ISITE000562 Click to Show/Hide the Full List
mod site chr4:138196834-138196835:- [17]
Sequence AAACCCTGTCTCTACTAAAAATACAAAAATAAGCTGAGTGT
Transcript ID List ENST00000509248.1; rmsk_1451306; ENST00000280612.9
External Link RMBase: RNA-editing_site_106632
mod ID: A2ISITE000563 Click to Show/Hide the Full List
mod site chr4:138196852-138196853:- [17]
Sequence AGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATA
Transcript ID List ENST00000280612.9; ENST00000509248.1; rmsk_1451306
External Link RMBase: RNA-editing_site_106633
mod ID: A2ISITE000564 Click to Show/Hide the Full List
mod site chr4:138196853-138196854:- [17]
Sequence CAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAAT
Transcript ID List ENST00000280612.9; rmsk_1451306; ENST00000509248.1
External Link RMBase: RNA-editing_site_106634
mod ID: A2ISITE000565 Click to Show/Hide the Full List
mod site chr4:138196860-138196861:- [17]
Sequence TTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTAC
Transcript ID List ENST00000509248.1; ENST00000280612.9; rmsk_1451306
External Link RMBase: RNA-editing_site_106635
mod ID: A2ISITE000566 Click to Show/Hide the Full List
mod site chr4:138196862-138196863:- [17]
Sequence GCTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCT
Transcript ID List ENST00000509248.1; ENST00000280612.9; rmsk_1451306
External Link RMBase: RNA-editing_site_106636
mod ID: A2ISITE000567 Click to Show/Hide the Full List
mod site chr4:138196863-138196864:- [17]
Sequence AGCTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTC
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106637
mod ID: A2ISITE000568 Click to Show/Hide the Full List
mod site chr4:138196872-138196873:- [17]
Sequence GAGGTCAAGAGCTTGAGACCAGCCTGGCCAACATGGTGAAA
Transcript ID List rmsk_1451306; ENST00000509248.1; ENST00000280612.9
External Link RMBase: RNA-editing_site_106638
mod ID: A2ISITE000569 Click to Show/Hide the Full List
mod site chr4:138196877-138196878:- [17]
Sequence CACCAGAGGTCAAGAGCTTGAGACCAGCCTGGCCAACATGG
Transcript ID List ENST00000280612.9; rmsk_1451306; ENST00000509248.1
External Link RMBase: RNA-editing_site_106639
mod ID: A2ISITE000571 Click to Show/Hide the Full List
mod site chr4:138196885-138196886:- [17]
Sequence GGGCGTATCACCAGAGGTCAAGAGCTTGAGACCAGCCTGGC
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106640
mod ID: A2ISITE000572 Click to Show/Hide the Full List
mod site chr4:138196891-138196892:- [17]
Sequence CAAGGTGGGCGTATCACCAGAGGTCAAGAGCTTGAGACCAG
Transcript ID List ENST00000280612.9; ENST00000509248.1; rmsk_1451306
External Link RMBase: RNA-editing_site_106641
mod ID: A2ISITE000573 Click to Show/Hide the Full List
mod site chr4:138196893-138196894:- [17]
Sequence GCCAAGGTGGGCGTATCACCAGAGGTCAAGAGCTTGAGACC
Transcript ID List rmsk_1451306; ENST00000280612.9; ENST00000509248.1
External Link RMBase: RNA-editing_site_106642
5-methylcytidine (m5C)
In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE003334 Click to Show/Hide the Full List
mod site chr4:138171131-138171132:- [18]
Sequence ATTAGAACAACCACCTGTTTCACTAATAACTTACCCCTGAT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m5C_site_34338
mod ID: M5CSITE003335 Click to Show/Hide the Full List
mod site chr4:138223279-138223280:- [18]
Sequence TGAGTGTCAGCTGGAGCGCCCGGATCCAGATTTTCTTAACC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m5C_site_34339
N6-methyladenosine (m6A)
In total 108 m6A sequence/site(s) in this target gene
mod ID: M6ASITE067671 Click to Show/Hide the Full List
mod site chr4:138164148-138164149:- [19]
Sequence ACCATTTTTGTACATATTTTACTTGAAAATATTTTAAATGG
Motif Score 2.494845238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651120
mod ID: M6ASITE067672 Click to Show/Hide the Full List
mod site chr4:138164197-138164198:- [19]
Sequence TTATATGTATTATACCTGTCACGCTTCTAGTTGCTTCAACC
Motif Score 2.021232143
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651121
mod ID: M6ASITE067673 Click to Show/Hide the Full List
mod site chr4:138164392-138164393:- [20]
Sequence AGAGTTCTGGTACTGCAATCACAATGCCAGATGGTGTTTAT
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651122
mod ID: M6ASITE067674 Click to Show/Hide the Full List
mod site chr4:138164474-138164475:- [20]
Sequence TTCCTAGCACTGATGCCTGCACAAGCATGTGATATGTGAAA
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651123
mod ID: M6ASITE067675 Click to Show/Hide the Full List
mod site chr4:138164527-138164528:- [21]
Sequence GATATAAATGGTGCAGAGAGACTTTCATCTGTGGATTGCGT
Motif Score 3.319380952
Cell/Tissue List A549
Seq Type List m6A-CLIP/IP
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651124
mod ID: M6ASITE067676 Click to Show/Hide the Full List
mod site chr4:138164657-138164658:- [20]
Sequence GGGGATTGTGTGTATTTTATACAAATTTAATACAATGTCTT
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651125
mod ID: M6ASITE067677 Click to Show/Hide the Full List
mod site chr4:138165021-138165022:- [19]
Sequence AATATTTTTCATATTCTGTGACAAGCATTTATAATTTGCAA
Motif Score 2.859755952
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651126
mod ID: M6ASITE067678 Click to Show/Hide the Full List
mod site chr4:138165191-138165192:- [19]
Sequence TTGTAAGCATATCTGAATTTACTTTATAAAGATGGTTTTAG
Motif Score 2.494845238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651127
mod ID: M6ASITE067679 Click to Show/Hide the Full List
mod site chr4:138165279-138165280:- [19]
Sequence GGATTACATGGTAGTGATGCACTGGTAGAAATGGTTTTTAG
Motif Score 3.252583333
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651128
mod ID: M6ASITE067680 Click to Show/Hide the Full List
mod site chr4:138165294-138165295:- [19]
Sequence GAGCTTGCGTAGAATGGATTACATGGTAGTGATGCACTGGT
Motif Score 2.07285119
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651129
mod ID: M6ASITE067681 Click to Show/Hide the Full List
mod site chr4:138165338-138165339:- [22]
Sequence GGGTCTTCATTTTCTGACAGACAGGATTTGACTCAATATTT
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651130
mod ID: M6ASITE067682 Click to Show/Hide the Full List
mod site chr4:138165365-138165366:- [22]
Sequence TGTACTGAATACTTCGGCAAACTTATTGGGTCTTCATTTTC
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651131
mod ID: M6ASITE067683 Click to Show/Hide the Full List
mod site chr4:138165382-138165383:- [19]
Sequence CAAGACAAATGGCCTCTTGTACTGAATACTTCGGCAAACTT
Motif Score 3.278136905
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651132
mod ID: M6ASITE067684 Click to Show/Hide the Full List
mod site chr4:138165398-138165399:- [22]
Sequence ACATGTCAGAAAAAGGCAAGACAAATGGCCTCTTGTACTGA
Motif Score 2.897386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651133
mod ID: M6ASITE067685 Click to Show/Hide the Full List
mod site chr4:138165418-138165419:- [20]
Sequence CCTGTGATTTTATAGTATGCACATGTCAGAAAAAGGCAAGA
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651134
mod ID: M6ASITE067686 Click to Show/Hide the Full List
mod site chr4:138165478-138165479:- [22]
Sequence TCCCTATGCCAAACAGGTGAACAAACGTAGTTGTTTTTTAC
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651135
mod ID: M6ASITE067687 Click to Show/Hide the Full List
mod site chr4:138165486-138165487:- [22]
Sequence TTGTTTTCTCCCTATGCCAAACAGGTGAACAAACGTAGTTG
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651136
mod ID: M6ASITE067688 Click to Show/Hide the Full List
mod site chr4:138165509-138165510:- [20]
Sequence ATCATTTAATGCTATGAGATACATTGTTTTCTCCCTATGCC
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651137
mod ID: M6ASITE067689 Click to Show/Hide the Full List
mod site chr4:138165576-138165577:- [20]
Sequence CTTTTCACTAGAACTTCTCAACATTTGGGAACTTTGCAAAT
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651138
mod ID: M6ASITE067690 Click to Show/Hide the Full List
mod site chr4:138165635-138165636:- [19]
Sequence TTTGGTTATTTTGAATACAGACATTGGCTCCAAATTTTCAT
Motif Score 2.897386905
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651139
mod ID: M6ASITE067691 Click to Show/Hide the Full List
mod site chr4:138165639-138165640:- [19]
Sequence ATATTTTGGTTATTTTGAATACAGACATTGGCTCCAAATTT
Motif Score 2.110482143
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651140
mod ID: M6ASITE067692 Click to Show/Hide the Full List
mod site chr4:138165708-138165709:- [19]
Sequence CAACACTTTACTCTTTTAGGACAATTCCTAGAATCTATAGT
Motif Score 3.643047619
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651141
mod ID: M6ASITE067693 Click to Show/Hide the Full List
mod site chr4:138165729-138165730:- [20]
Sequence TATTCATGTTCAGAAAGGAAACAACACTTTACTCTTTTAGG
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651142
mod ID: M6ASITE067694 Click to Show/Hide the Full List
mod site chr4:138165785-138165786:- [19]
Sequence CAAATTTCTATAAATTTCCTACTTAAGTCTTAAGAACTGGG
Motif Score 2.500660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651143
mod ID: M6ASITE067695 Click to Show/Hide the Full List
mod site chr4:138165817-138165818:- [19]
Sequence TCCTTATGAATGTTATTACTACTGGTATAAATCAAATTTCT
Motif Score 2.500660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651144
mod ID: M6ASITE067696 Click to Show/Hide the Full List
mod site chr4:138165820-138165821:- [19]
Sequence TTTTCCTTATGAATGTTATTACTACTGGTATAAATCAAATT
Motif Score 2.494845238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651145
mod ID: M6ASITE067697 Click to Show/Hide the Full List
mod site chr4:138165913-138165914:- [20]
Sequence TAAATCACTATGATTATTGCACAAACAACCAGAATTCTCCA
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651146
mod ID: M6ASITE067698 Click to Show/Hide the Full List
mod site chr4:138166086-138166087:- [20]
Sequence TTTCTCCTTCATTCCAAAGTACAAACATACTTTGAAGAATG
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651147
mod ID: M6ASITE067699 Click to Show/Hide the Full List
mod site chr4:138166194-138166195:- [20]
Sequence CTTGGAAGCACAGTCATATCACACTGGGAGGCAATGCAATG
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651148
mod ID: M6ASITE067700 Click to Show/Hide the Full List
mod site chr4:138166239-138166240:- [19]
Sequence TTTAGACATCAAATTTTCCTACTAACTAACTTTATTAGATG
Motif Score 2.500660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651149
mod ID: M6ASITE067701 Click to Show/Hide the Full List
mod site chr4:138166254-138166255:- [22]
Sequence ATGTGTATTATAAAATTTAGACATCAAATTTTCCTACTAAC
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651150
mod ID: M6ASITE067702 Click to Show/Hide the Full List
mod site chr4:138166498-138166499:- [19]
Sequence TTAATGTATTGGTTAGGAGAACTGCTTGCTAAGTCCTTATT
Motif Score 3.373380952
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651151
mod ID: M6ASITE067703 Click to Show/Hide the Full List
mod site chr4:138166582-138166583:- [20]
Sequence CCAACTTTGTTCCAGAGTGAACATGCTTTTTTTCCTCAACA
Motif Score 2.951386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651152
mod ID: M6ASITE067704 Click to Show/Hide the Full List
mod site chr4:138166638-138166639:- [22]
Sequence GTTAACAATTCTCTCACAAAACTGTAGAGCATTAGGCATCT
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651153
mod ID: M6ASITE067705 Click to Show/Hide the Full List
mod site chr4:138166643-138166644:- [20]
Sequence TTACAGTTAACAATTCTCTCACAAAACTGTAGAGCATTAGG
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651154
mod ID: M6ASITE067706 Click to Show/Hide the Full List
mod site chr4:138166766-138166767:- [20]
Sequence GTTACTATTGGCCTTAAAATACACAGAGGACGGTTACAGTG
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651155
mod ID: M6ASITE067707 Click to Show/Hide the Full List
mod site chr4:138166858-138166859:- [19]
Sequence AACAATGAATTTATATAATTACCTAGATTTTCTTAGTGTGA
Motif Score 2.052208333
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651156
mod ID: M6ASITE067708 Click to Show/Hide the Full List
mod site chr4:138166888-138166889:- [20]
Sequence GTGAGATAACTGTCCTTTCTACAACCTCATAACAATGAATT
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651157
mod ID: M6ASITE067709 Click to Show/Hide the Full List
mod site chr4:138166926-138166927:- [19]
Sequence CATAGTCTCACAGGAAATTCACCAATTTTCCATATGTCGTG
Motif Score 2.026654762
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651158
mod ID: M6ASITE067710 Click to Show/Hide the Full List
mod site chr4:138167472-138167473:- [19]
Sequence CCTTAGTTTATTAGTACTGTACTTCAAAAAGATTTTTAAAT
Motif Score 3.278136905
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651159
mod ID: M6ASITE067711 Click to Show/Hide the Full List
mod site chr4:138167612-138167613:- [19]
Sequence TGATAGCCTCTGTTTACATTACTTGTATATGGGCAAAATAA
Motif Score 2.494845238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651160
mod ID: M6ASITE067712 Click to Show/Hide the Full List
mod site chr4:138167617-138167618:- [20]
Sequence CACCTTGATAGCCTCTGTTTACATTACTTGTATATGGGCAA
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651161
mod ID: M6ASITE067713 Click to Show/Hide the Full List
mod site chr4:138167687-138167688:- [20]
Sequence TTAAAATATGGCATTGTATAACAACTGGGAAGAAGCTCATA
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651162
mod ID: M6ASITE067714 Click to Show/Hide the Full List
mod site chr4:138168125-138168126:- [19]
Sequence GCAAAGTTGTGTACACTTCTACCCCCACAAAATCTGCATTG
Motif Score 2.05802381
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List rmsk_1451273; ENST00000280612.9
External Link RMBase: m6A_site_651163
mod ID: M6ASITE067715 Click to Show/Hide the Full List
mod site chr4:138168133-138168134:- [20]
Sequence GAAGACCAGCAAAGTTGTGTACACTTCTACCCCCACAAAAT
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List rmsk_1451273; ENST00000280612.9
External Link RMBase: m6A_site_651164
mod ID: M6ASITE067716 Click to Show/Hide the Full List
mod site chr4:138168217-138168218:- [20]
Sequence CTTCAGTGCCTCTCACTTAGACATGTTCCATTCGAGGTCCT
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List rmsk_1451273; ENST00000280612.9
External Link RMBase: m6A_site_651165
mod ID: M6ASITE067717 Click to Show/Hide the Full List
mod site chr4:138168345-138168346:- [22]
Sequence GGAAATGAAAGATAGTATGGACTGAAGGTAACAATATTTTA
Motif Score 4.065041667
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651166
mod ID: M6ASITE067718 Click to Show/Hide the Full List
mod site chr4:138168384-138168385:- [22]
Sequence AAGGTATGAAAAGATAAAAAACCGAAGGCCAGAGAATCAGG
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651167
mod ID: M6ASITE067719 Click to Show/Hide the Full List
mod site chr4:138168520-138168521:- [22]
Sequence CATAACAGAATTCCTCATGAACTGTAATCAGTCTACAGGAA
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651168
mod ID: M6ASITE067720 Click to Show/Hide the Full List
mod site chr4:138168574-138168575:- [19]
Sequence GTTTCCCCAATTACAATTTGACATATCAATAGAGGGTTAAC
Motif Score 2.859755952
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651169
mod ID: M6ASITE067721 Click to Show/Hide the Full List
mod site chr4:138168582-138168583:- [20]
Sequence GTAAAATTGTTTCCCCAATTACAATTTGACATATCAATAGA
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651170
mod ID: M6ASITE067722 Click to Show/Hide the Full List
mod site chr4:138168665-138168666:- [19]
Sequence GGTTACGTTAGCAATGCATGACGGTTTCTCCAACACTAAGA
Motif Score 2.833690476
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651171
mod ID: M6ASITE067723 Click to Show/Hide the Full List
mod site chr4:138168709-138168710:- [20]
Sequence GTAGCTCCTCAGCCCTGTGGACACAAAATTTGGACAGCTTA
Motif Score 3.643047619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651172
mod ID: M6ASITE067724 Click to Show/Hide the Full List
mod site chr4:138168750-138168751:- [20]
Sequence ATGGCTGACTTCGGTTCCCAACATGCGTATGCATTTAGACT
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651173
mod ID: M6ASITE067725 Click to Show/Hide the Full List
mod site chr4:138169254-138169255:- [20]
Sequence ATTCTCAAAAACTCTCCTGAACACTTATTTATATATATGTT
Motif Score 2.951386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651174
mod ID: M6ASITE067726 Click to Show/Hide the Full List
mod site chr4:138169341-138169342:- [20]
Sequence TTAGGACTCATCATGAGAAGACACAGTTCCTTTAATCAGGA
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651175
mod ID: M6ASITE067727 Click to Show/Hide the Full List
mod site chr4:138169697-138169698:- [20]
Sequence ACTAGGCTCATAGAATTTAAACAAGCAAATTTTCCTGAGCT
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651176
mod ID: M6ASITE067728 Click to Show/Hide the Full List
mod site chr4:138169717-138169718:- [22]
Sequence TATTTTTTTTTTCCCCATAGACTAGGCTCATAGAATTTAAA
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651177
mod ID: M6ASITE067729 Click to Show/Hide the Full List
mod site chr4:138169788-138169789:- [20]
Sequence TAAATATTGTTCATTTGTCCACATCTCTCCCTATGATATGT
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651178
mod ID: M6ASITE067730 Click to Show/Hide the Full List
mod site chr4:138169941-138169942:- [20]
Sequence TTTCAATTTTGCTCTTGAAAACATTTAATATATATCCAAGA
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651179
mod ID: M6ASITE067731 Click to Show/Hide the Full List
mod site chr4:138170033-138170034:- [20]
Sequence ATTAAAATTATTAAAGGCAAACATAGAATTCATAAAAAATT
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651180
mod ID: M6ASITE067732 Click to Show/Hide the Full List
mod site chr4:138170508-138170509:- [22]
Sequence AGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATA
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List rmsk_1451278; ENST00000280612.9
External Link RMBase: m6A_site_651181
mod ID: M6ASITE067733 Click to Show/Hide the Full List
mod site chr4:138170531-138170532:- [22]
Sequence CCTGAGGTCGGGAGTTCTAGACCAGCCTGACCAACATGGAG
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9; rmsk_1451278
External Link RMBase: m6A_site_651182
mod ID: M6ASITE067734 Click to Show/Hide the Full List
mod site chr4:138170595-138170596:- [20]
Sequence TGAGCCGGGCATGGTGGCTTACATCTGTAATCCCAGCACTT
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List rmsk_1451278; ENST00000280612.9
External Link RMBase: m6A_site_651183
mod ID: M6ASITE067735 Click to Show/Hide the Full List
mod site chr4:138170704-138170705:- [22]
Sequence TCATTCAACTTGCAAAAGAGACAACTGATAAGAAGAAAATT
Motif Score 2.897386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651184
mod ID: M6ASITE067736 Click to Show/Hide the Full List
mod site chr4:138170736-138170737:- [20]
Sequence AGGCTTTGTCAGTAATTTCCACACCTTAATTATCATTCAAC
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651185
mod ID: M6ASITE067737 Click to Show/Hide the Full List
mod site chr4:138170794-138170795:- [20]
Sequence TGTCGCTGTAAATAAGATTTACAACTGATGTTTCTAGAAAA
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651186
mod ID: M6ASITE067738 Click to Show/Hide the Full List
mod site chr4:138170835-138170836:- [20]
Sequence TTAGGAAAAGGCATATATTAACATAAAAATTGCAAAAGAAA
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651187
mod ID: M6ASITE067739 Click to Show/Hide the Full List
mod site chr4:138170949-138170950:- [20]
Sequence TTAAATTTATGGCTATTTTTACACGATGATGAATTTTGACA
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651188
mod ID: M6ASITE067740 Click to Show/Hide the Full List
mod site chr4:138170998-138170999:- [20]
Sequence CCATATCTGTAATCATATCTACATGCAATGTTAGTAATTCT
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651189
mod ID: M6ASITE067741 Click to Show/Hide the Full List
mod site chr4:138171098-138171099:- [22]
Sequence CCCCTGATGAGTCTATCTAAACATATGCATTTTAAGCCTTC
Motif Score 2.20572619
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651190
mod ID: M6ASITE067742 Click to Show/Hide the Full List
mod site chr4:138171145-138171146:- [22]
Sequence GGTATTAAATCCTCATTAGAACAACCACCTGTTTCACTAAT
Motif Score 2.951386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651191
mod ID: M6ASITE067743 Click to Show/Hide the Full List
mod site chr4:138171325-138171326:- [22]
Sequence TAGGGGCTACTGTTTATGAGACACATCCAGGAGTTATGTTT
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651192
mod ID: M6ASITE067744 Click to Show/Hide the Full List
mod site chr4:138171337-138171338:- [19]
Sequence AAGAAGAGTTTCTAGGGGCTACTGTTTATGAGACACATCCA
Motif Score 2.500660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651193
mod ID: M6ASITE067745 Click to Show/Hide the Full List
mod site chr4:138171389-138171390:- [22]
Sequence TTATACCCAGAGCACTTTGAACAAAGGTCAGTGGGGATTGT
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651194
mod ID: M6ASITE067746 Click to Show/Hide the Full List
mod site chr4:138171428-138171429:- [22]
Sequence GATACCAATTTAGATAACAAACACTCATGCTTTAATGGATT
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651195
mod ID: M6ASITE067747 Click to Show/Hide the Full List
mod site chr4:138171572-138171573:- [20]
Sequence GGTTTTGTAAAGATGGTTTTACACACTATAGATGTCTATAC
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651196
mod ID: M6ASITE067750 Click to Show/Hide the Full List
mod site chr4:138171615-138171616:- [22]
Sequence AAAGAACCTTCAAATTGAAGACTGAGATTTTTCTGTATATA
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651199
mod ID: M6ASITE067752 Click to Show/Hide the Full List
mod site chr4:138171630-138171631:- [22]
Sequence ATATGTTAGCACGGCAAAGAACCTTCAAATTGAAGACTGAG
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651200
mod ID: M6ASITE067753 Click to Show/Hide the Full List
mod site chr4:138171679-138171680:- [22]
Sequence GGGTTAGGAGAAAAGACTAGACAATTACTATGTGGTCATTC
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651201
mod ID: M6ASITE067754 Click to Show/Hide the Full List
mod site chr4:138171684-138171685:- [22]
Sequence TATTGGGGTTAGGAGAAAAGACTAGACAATTACTATGTGGT
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651202
mod ID: M6ASITE067755 Click to Show/Hide the Full List
mod site chr4:138171805-138171806:- [23]
Sequence ATATATTTTAGCATATTCGAACTAATTTCTAAGAAATTTAG
Motif Score 3.373380952
Cell/Tissue List A549; HEK293T; Huh7; TIME
Seq Type List MeRIP-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651203
mod ID: M6ASITE067756 Click to Show/Hide the Full List
mod site chr4:138171851-138171852:- [22]
Sequence AATTACAACTTTGGTGATAAACAAAAGGAGTCAGTTATTTT
Motif Score 2.20572619
Cell/Tissue List HeLa; HEK293T; A549; Huh7; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651204
mod ID: M6ASITE067757 Click to Show/Hide the Full List
mod site chr4:138171867-138171868:- [20]
Sequence TTCTGAAAGTCTAGAGAATTACAACTTTGGTGATAAACAAA
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651205
mod ID: M6ASITE067758 Click to Show/Hide the Full List
mod site chr4:138171914-138171915:- [22]
Sequence GGCAATCTGCCCAAGGGGAGACACAAAATAGGGATTTTTAC
Motif Score 2.897386905
Cell/Tissue List HeLa; HEK293T; A549; hESC-HEK293T; hESCs; fibroblasts; MM6; Huh7; MSC; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq; DART-seq; MAZTER-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651206
mod ID: M6ASITE067759 Click to Show/Hide the Full List
mod site chr4:138171946-138171947:- [22]
Sequence GATAAGTTATGAACTAATGGACTTGAGATCTTGGCAATCTG
Motif Score 4.065041667
Cell/Tissue List HeLa; HEK293T; A549; HepG2; hESCs; fibroblasts; MM6; Huh7; MSC; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651207
mod ID: M6ASITE067760 Click to Show/Hide the Full List
mod site chr4:138171954-138171955:- [22]
Sequence CAGAAGAAGATAAGTTATGAACTAATGGACTTGAGATCTTG
Motif Score 3.373380952
Cell/Tissue List HeLa; HEK293T; A549; HepG2; hESCs; fibroblasts; MM6; Huh7; MSC; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651208
mod ID: M6ASITE067761 Click to Show/Hide the Full List
mod site chr4:138171997-138171998:- [20]
Sequence GAGAAAATAACCAGAACATTACAAATAATACTGGAAGTTGT
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651209
mod ID: M6ASITE067762 Click to Show/Hide the Full List
mod site chr4:138172002-138172003:- [22]
Sequence TTGTAGAGAAAATAACCAGAACATTACAAATAATACTGGAA
Motif Score 2.951386905
Cell/Tissue List HeLa; HEK293T; hESCs; fibroblasts; A549; Huh7; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651210
mod ID: M6ASITE067763 Click to Show/Hide the Full List
mod site chr4:138179241-138179242:- [22]
Sequence TTTATTATATGGGACAAGAAACCCAGGTGGTTTAGAATAAT
Motif Score 2.185083333
Cell/Tissue List HeLa; HEK293T; A549
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651211
mod ID: M6ASITE067764 Click to Show/Hide the Full List
mod site chr4:138179248-138179249:- [22]
Sequence TTATCTCTTTATTATATGGGACAAGAAACCCAGGTGGTTTA
Motif Score 3.643047619
Cell/Tissue List HeLa; HEK293T; A549
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651212
mod ID: M6ASITE067765 Click to Show/Hide the Full List
mod site chr4:138179323-138179324:- [22]
Sequence TGCCCTTTCCCTCTATTCGGACCCATTTAGTACAGGGATTG
Motif Score 3.622404762
Cell/Tissue List HeLa; A549
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651213
mod ID: M6ASITE067766 Click to Show/Hide the Full List
mod site chr4:138179360-138179361:- [20]
Sequence TCCCAGCTTTGTTTTCCTTCACATGCCTCTTCATGGTTGCC
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651214
mod ID: M6ASITE067767 Click to Show/Hide the Full List
mod site chr4:138180671-138180672:- [20]
Sequence TGGGCTGATTTATCTTCGATACAAATGCCCAGATATGCATC
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000509248.1; ENST00000280612.9
External Link RMBase: m6A_site_651215
mod ID: M6ASITE067768 Click to Show/Hide the Full List
mod site chr4:138180755-138180756:- [22]
Sequence GATAATGCTCTTCTCTGGAGACCTCGACAGTCTTTTGAATT
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651216
mod ID: M6ASITE067769 Click to Show/Hide the Full List
mod site chr4:138185185-138185186:- [20]
Sequence TCACCATTGGCTATGTGCTGACAAATGTGGCCTACTTTACG
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651217
mod ID: M6ASITE067770 Click to Show/Hide the Full List
mod site chr4:138214593-138214594:- [22]
Sequence TGTTACTGAAGAAGTAGAAAACCCTGAAAAGTAAGTAGCCA
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651218
mod ID: M6ASITE067771 Click to Show/Hide the Full List
mod site chr4:138219352-138219353:- [22]
Sequence AATTACAGGTCAAACGCAGAACTTTAAAGACGCCTTTTCAG
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9; ENST00000509248.1
External Link RMBase: m6A_site_651219
mod ID: M6ASITE067772 Click to Show/Hide the Full List
mod site chr4:138232300-138232301:- [22]
Sequence ATTCAATGTGAAATCCCTGAACTTGCGATCAAGCTCATTAC
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651220
mod ID: M6ASITE067773 Click to Show/Hide the Full List
mod site chr4:138232330-138232331:- [22]
Sequence TTTGGACGCTACATTCTGGAACCATTTTTTATTCAATGTGA
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651221
mod ID: M6ASITE067774 Click to Show/Hide the Full List
mod site chr4:138236338-138236339:- [22]
Sequence TTTGTACGAGTCTGGGTGGAACTCCTCATAATACGGTAAGA
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651222
mod ID: M6ASITE067775 Click to Show/Hide the Full List
mod site chr4:138236424-138236425:- [22]
Sequence TGTCTTATGCTGAATTGGGAACAACTATAAAGAAATCTGGA
Motif Score 2.951386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651223
mod ID: M6ASITE067776 Click to Show/Hide the Full List
mod site chr4:138241854-138241855:- [22]
Sequence TCCTAAGGGCGTGCTCCAGAACACGGGCAGCGTGGGCATGT
Motif Score 2.951386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651224
mod ID: M6ASITE067777 Click to Show/Hide the Full List
mod site chr4:138241983-138241984:- [20]
Sequence GAGGCTGCCTTCCCTGGGCAACAAGGAGCCACCTGGGCAGG
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651225
mod ID: M6ASITE067778 Click to Show/Hide the Full List
mod site chr4:138242132-138242133:- [22]
Sequence TCGATCAGTAACACCAAGAGACACCAAAGTTGAAAGTTTTG
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; HEK293T; A549; MM6; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651226
mod ID: M6ASITE067779 Click to Show/Hide the Full List
mod site chr4:138242155-138242156:- [22]
Sequence CAGTCTGAAAGCAGAGGAAGACATCGATCAGTAACACCAAG
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; HEK293T; A549; GM12878; MM6; iSLK; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651227
mod ID: M6ASITE067780 Click to Show/Hide the Full List
mod site chr4:138242176-138242177:- [22]
Sequence ACACTATAGCGCTGAGAGAGACAGTCTGAAAGCAGAGGAAG
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; HEK293T; A549; hESC-HEK293T; GM12878; MM6; iSLK; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651228
mod ID: M6ASITE067781 Click to Show/Hide the Full List
mod site chr4:138242196-138242197:- [22]
Sequence CTTTGAGTTTTCACCTGTGAACACTATAGCGCTGAGAGAGA
Motif Score 2.951386905
Cell/Tissue List HeLa; HepG2; HEK293T; A549; GM12878; MM6; iSLK; TIME; HEC-1-A
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000280612.9
External Link RMBase: m6A_site_651229
Pseudouridine (Pseudo)
In total 3 m6A sequence/site(s) in this target gene
mod ID: PSESITE000204 Click to Show/Hide the Full List
mod site chr4:138166302-138166303:- [24]
Sequence GCATGTTAAAGCTGTATAATTTGTTGGGTTGTGAGTGGTCT
Transcript ID List ENST00000280612.9
External Link RMBase: Pseudo_site_3796
mod ID: PSESITE000205 Click to Show/Hide the Full List
mod site chr4:138166893-138166894:- [24]
Sequence ATGTCGTGAGATAACTGTCCTTTCTACAACCTCATAACAAT
Transcript ID List ENST00000280612.9
External Link RMBase: Pseudo_site_3797
mod ID: PSESITE000206 Click to Show/Hide the Full List
mod site chr4:138171134-138171135:- [24]
Sequence CTCATTAGAACAACCACCTGTTTCACTAATAACTTACCCCT
Transcript ID List ENST00000280612.9
External Link RMBase: Pseudo_site_3798