m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00327)

Target Name	Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1)
Synonyms	MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; ERK2; PRKM1; PRKM2 Click to Show/Hide
Gene Name	MAPK1
Chromosomal Location	22q11.22
Family	protein kinase superfamily; CMGC Ser/Thr protein kinase family; MAP kinase subfamily
Function	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis. The substrates include transcription factors (such as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT, PXN, SORBS3 or STMN1), regulators of apoptosis (such as BAD, BTG2, CASP9, DAPK1, IER3, MCL1 or PPARG), regulators of translation (such as EIF4EBP1) and a variety of other signaling-related molecules (like ARHGEF2, DCC, FRS2 or GRB10). Protein kinases (such as RAF1, RPS6KA1/RSK1, RPS6KA3/RSK2, RPS6KA2/RSK3, RPS6KA6/RSK4, SYK, MKNK1/MNK1, MKNK2/MNK2, RPS6KA5/MSK1, RPS6KA4/MSK2, MAPKAPK3 or MAPKAPK5) and phosphatases (such as DUSP1, DUSP4, DUSP6 or DUSP16) are other substrates which enable the propagation the MAPK/ERK signal to additional cytosolic and nuclear targets, thereby extending the specificity of the cascade. Mediates phosphorylation of TPR in response to EGF stimulation. May play a role in the spindle assembly checkpoint. Phosphorylates PML and promotes its interaction with PIN1, leading to PML degradation. Phosphorylates CDK2AP2 (By similarity). ; Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity. Click to Show/Hide
Gene ID	5594
Uniprot ID	MK01_HUMAN
HGNC ID	HGNC:6871
KEGG ID	hsa:5594

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

MAPK1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

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Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) [READER]

Regulator Info

In total 3 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	hnRNPA2B1 promotes colon cancer progression via the MAPK pathway. hnRNPA2B1 is an upstream regulator of the ERK/Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) pathway and inhibition of MAPK signaling blocked the effects of hnRNPA2B1.
Target Regulation	Up regulation
Responsed Disease	Colon cancer		ICD-11: 2B90	Disease Info
Pathway Response	MAPK signaling			hsa04010
Cell Process	Arrest cell cycle at G0/G1 phase
Cell Process	Cell apoptosis
In-vitro Model	HCT 116	Colon carcinoma	Homo sapiens	CVCL_0291
In-vitro Model	SW480	Colon adenocarcinoma	Homo sapiens	CVCL_0546
In-vivo Model	Four-week-old male BALB/c nude mice (purchased from Lingchang company) were randomly divided into three groups, each group has five mice. Each of the mice was injected subcutaneously on the right lateral back with 1 × 10⁶ of each lentivirus infected SW480 cells in which hnRNPA2B1 was knocked out or negative control cells. Mice were killed at day 29, and tumors were then isolated, photographed.
Experiment 2 Reporting the m6A Methylation Regulator of This Target Gene				[2]
Response Summary	In breast cancer, modest stable overexpression of A2B1 in MCF-7 cells (MCF-7-A2B1 cells) resulted in tamoxifen and fulvestrant- resistance whereas knockdown of A2B1 in LCC9 and LY2 cells restored tamoxifen and fulvestrant, endocrine-sensitivity. MCF-7-A2B1 cells have increased ER-alpha and reduced miR-222-3p that targets ER-alpha. MCF-7-A2B1 have activated AKT and Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) that depend on A2B1 expression and are growth inhibited by inhibitors of these pathways.
Target Regulation	Up regulation
Responsed Disease	Breast cancer		ICD-11: 2C60	Disease Info
Responsed Drug	Fulvestrant		Approved	Drug Info
Pathway Response	MAPK signaling pathway			hsa04010
Pathway Response	PI3K-Akt signaling pathway			hsa04151
Cell Process	Cell migration and invasion
In-vitro Model	HCC1806	Breast squamous cell carcinoma	Homo sapiens	CVCL_1258
	MCF-7	Invasive breast carcinoma	Homo sapiens	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062
	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
	T-47D	Invasive breast carcinoma	Homo sapiens	CVCL_0553
Experiment 3 Reporting the m6A Methylation Regulator of This Target Gene				[2]
Response Summary	In breast cancer, modest stable overexpression of A2B1 in MCF-7 cells (MCF-7-A2B1 cells) resulted in tamoxifen and fulvestrant - resistance whereas knockdown of A2B1 in LCC9 and LY2 cells restored tamoxifen and fulvestrant, endocrine-sensitivity. MCF-7-A2B1 cells have increased ER-alpha and reduced miR-222-3p that targets ER-alpha. MCF-7-A2B1 have activated AKT and Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) that depend on A2B1 expression and are growth inhibited by inhibitors of these pathways.
Target Regulation	Up regulation
Responsed Disease	Breast cancer		ICD-11: 2C60	Disease Info
Responsed Drug	Tamoxifen		Approved	Drug Info
Pathway Response	MAPK signaling pathway			hsa04010
Pathway Response	PI3K-Akt signaling pathway			hsa04151
Cell Process	Cell migration and invasion
In-vitro Model	HCC1806	Breast squamous cell carcinoma	Homo sapiens	CVCL_1258
	MCF-7	Invasive breast carcinoma	Homo sapiens	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062
	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
	T-47D	Invasive breast carcinoma	Homo sapiens	CVCL_0553

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) [READER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[5]
Response Summary	N6-methyladenosine (m6A) methylation modification is implicated in the pathogenesis of lung ischemia-reperfusion injury. YTHDF3 or IGF2BP2 knockdown inhibited hypoxia/reoxygenation-activated p38, Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1), AKT, and NF-Kappa-B pathways in BEAS-2B cells, and inhibited p-p65, IL-1-beta and TNF-alpha secretion.
Target Regulation	Up regulation
Responsed Disease	Gangrene or necrosis of lung		ICD-11: CA43	Disease Info
Pathway Response	MAPK signaling pathway			hsa04010
	PI3K-Akt signaling pathway			hsa04151
	Apoptosis			hsa04210
Cell Process	Biological regulation
	Cell apoptosis
In-vitro Model	BEAS-2B	Normal	Homo sapiens	CVCL_0168
In-vivo Model	After being anesthetized with urethane (i.p.), SD rats were endotracheally intubated and ventilated using an animal ventilator under the conditions: respiratory rate of 70 breaths/min, tidal volume of 20 ml/kg, and inspiratory/expiratory ratio of 1:1.

YTH domain-containing family protein 3 (YTHDF3) [READER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[5]
Response Summary	N6-methyladenosine (m6A) methylation modification is implicated in the pathogenesis of lung ischemia-reperfusion injury. YTHDF3 or IGF2BP2 knockdown inhibited hypoxia/reoxygenation-activated p38, Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1), AKT, and NF-Kappa-B pathways in BEAS-2B cells, and inhibited p-p65, IL-1-beta and TNF-alpha secretion.
Target Regulation	Up regulation
Responsed Disease	Gangrene or necrosis of lung		ICD-11: CA43	Disease Info
Pathway Response	MAPK signaling pathway			hsa04010
	PI3K-Akt signaling pathway			hsa04151
	Apoptosis			hsa04210
Cell Process	Biological regulation
	Cell apoptosis
In-vitro Model	BEAS-2B	Normal	Homo sapiens	CVCL_0168
In-vivo Model	After being anesthetized with urethane (i.p.), SD rats were endotracheally intubated and ventilated using an animal ventilator under the conditions: respiratory rate of 70 breaths/min, tidal volume of 20 ml/kg, and inspiratory/expiratory ratio of 1:1.

Colon cancer [ICD-11: 2B90]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	hnRNPA2B1 promotes colon cancer progression via the MAPK pathway. hnRNPA2B1 is an upstream regulator of the ERK/Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) pathway and inhibition of MAPK signaling blocked the effects of hnRNPA2B1.
Responsed Disease	Colon cancer [ICD-11: 2B90]
Target Regulator	Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)		READER	Regulator Info
Target Regulation	Up regulation
Pathway Response	MAPK signaling			hsa04010
Cell Process	Arrest cell cycle at G0/G1 phase
	Cell apoptosis
In-vitro Model	HCT 116	Colon carcinoma	Homo sapiens	CVCL_0291
	SW480	Colon adenocarcinoma	Homo sapiens	CVCL_0546
In-vivo Model	Four-week-old male BALB/c nude mice (purchased from Lingchang company) were randomly divided into three groups, each group has five mice. Each of the mice was injected subcutaneously on the right lateral back with 1 × 10⁶ of each lentivirus infected SW480 cells in which hnRNPA2B1 was knocked out or negative control cells. Mice were killed at day 29, and tumors were then isolated, photographed.

Colorectal cancer [ICD-11: 2B91]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response		[]
Response Summary	WM_Score correlated highly with the regulation of transcription and post-transcriptional events contributing to the development of colorectal cancer. In response to anti-cancer drugs, WM_Score highly negatively correlated (drug sensitive) with drugs which targeted oncogenic related pathways, such as Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1), EGFR, and mTOR signaling pathways, positively correlated (drug resistance) with drugs which targeted in apoptosis and cell cycle. Importantly, the WM_Score was associated with the therapeutic efficacy of PD-L1 blockade, suggesting that the development of potential drugs targeting these "writers" to aid the clinical benefits of immunotherapy.
Responsed Disease	Colorectal cancer [ICD-11: 2B91]
Pathway Response	MAPK signaling pathway	hsa04010
	VEGF signaling pathway	hsa04370
	mTOR signaling pathway	hsa04150
	PD-L1 expression and PD-1 checkpoint pathway in cancer	hsa05235
	Apoptosis	hsa04210
Cell Process	Cell apoptosis

Breast cancer [ICD-11: 2C60]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[2]
Response Summary	In breast cancer, modest stable overexpression of A2B1 in MCF-7 cells (MCF-7-A2B1 cells) resulted in tamoxifen and fulvestrant- resistance whereas knockdown of A2B1 in LCC9 and LY2 cells restored tamoxifen and fulvestrant, endocrine-sensitivity. MCF-7-A2B1 cells have increased ER-alpha and reduced miR-222-3p that targets ER-alpha. MCF-7-A2B1 have activated AKT and Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) that depend on A2B1 expression and are growth inhibited by inhibitors of these pathways.
Responsed Disease	Breast cancer [ICD-11: 2C60]
Target Regulator	Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)		READER	Regulator Info
Target Regulation	Up regulation
Responsed Drug	Fulvestrant		Approved	Drug Info
Pathway Response	MAPK signaling pathway			hsa04010
Pathway Response	PI3K-Akt signaling pathway			hsa04151
Cell Process	Cell migration and invasion
In-vitro Model	HCC1806	Breast squamous cell carcinoma	Homo sapiens	CVCL_1258
	MCF-7	Invasive breast carcinoma	Homo sapiens	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062
	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
	T-47D	Invasive breast carcinoma	Homo sapiens	CVCL_0553
Experiment 2 Reporting the m6A-centered Disease Response				[2]
Response Summary	In breast cancer, modest stable overexpression of A2B1 in MCF-7 cells (MCF-7-A2B1 cells) resulted in tamoxifen and fulvestrant - resistance whereas knockdown of A2B1 in LCC9 and LY2 cells restored tamoxifen and fulvestrant, endocrine-sensitivity. MCF-7-A2B1 cells have increased ER-alpha and reduced miR-222-3p that targets ER-alpha. MCF-7-A2B1 have activated AKT and Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) that depend on A2B1 expression and are growth inhibited by inhibitors of these pathways.
Responsed Disease	Breast cancer [ICD-11: 2C60]
Target Regulator	Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)		READER	Regulator Info
Target Regulation	Up regulation
Responsed Drug	Tamoxifen		Approved	Drug Info
Pathway Response	MAPK signaling pathway			hsa04010
Pathway Response	PI3K-Akt signaling pathway			hsa04151
Cell Process	Cell migration and invasion
In-vitro Model	HCC1806	Breast squamous cell carcinoma	Homo sapiens	CVCL_1258
	MCF-7	Invasive breast carcinoma	Homo sapiens	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062
	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
	T-47D	Invasive breast carcinoma	Homo sapiens	CVCL_0553

Gangrene or necrosis of lung [ICD-11: CA43]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[5]
Response Summary	N6-methyladenosine (m6A) methylation modification is implicated in the pathogenesis of lung ischemia-reperfusion injury. YTHDF3 or IGF2BP2 knockdown inhibited hypoxia/reoxygenation-activated p38, Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1), AKT, and NF-Kappa-B pathways in BEAS-2B cells, and inhibited p-p65, IL-1-beta and TNF-alpha secretion.
Responsed Disease	Gangrene or necrosis of lung [ICD-11: CA43]
Target Regulator	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)		READER	Regulator Info
Target Regulation	Up regulation
Pathway Response	MAPK signaling pathway			hsa04010
	PI3K-Akt signaling pathway			hsa04151
	Apoptosis			hsa04210
Cell Process	Biological regulation
	Cell apoptosis
In-vitro Model	BEAS-2B	Normal	Homo sapiens	CVCL_0168
In-vivo Model	After being anesthetized with urethane (i.p.), SD rats were endotracheally intubated and ventilated using an animal ventilator under the conditions: respiratory rate of 70 breaths/min, tidal volume of 20 ml/kg, and inspiratory/expiratory ratio of 1:1.
Experiment 2 Reporting the m6A-centered Disease Response				[5]
Response Summary	N6-methyladenosine (m6A) methylation modification is implicated in the pathogenesis of lung ischemia-reperfusion injury. YTHDF3 or IGF2BP2 knockdown inhibited hypoxia/reoxygenation-activated p38, Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1), AKT, and NF-Kappa-B pathways in BEAS-2B cells, and inhibited p-p65, IL-1-beta and TNF-alpha secretion.
Responsed Disease	Gangrene or necrosis of lung [ICD-11: CA43]
Target Regulator	YTH domain-containing family protein 3 (YTHDF3)		READER	Regulator Info
Target Regulation	Up regulation
Pathway Response	MAPK signaling pathway			hsa04010
	PI3K-Akt signaling pathway			hsa04151
	Apoptosis			hsa04210
Cell Process	Biological regulation
	Cell apoptosis
In-vitro Model	BEAS-2B	Normal	Homo sapiens	CVCL_0168
In-vivo Model	After being anesthetized with urethane (i.p.), SD rats were endotracheally intubated and ventilated using an animal ventilator under the conditions: respiratory rate of 70 breaths/min, tidal volume of 20 ml/kg, and inspiratory/expiratory ratio of 1:1.

Fulvestrant [Approved]

Drug Info

In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response				[2]
Response Summary	In breast cancer, modest stable overexpression of A2B1 in MCF-7 cells (MCF-7-A2B1 cells) resulted in tamoxifen and fulvestrant- resistance whereas knockdown of A2B1 in LCC9 and LY2 cells restored tamoxifen and fulvestrant, endocrine-sensitivity. MCF-7-A2B1 cells have increased ER-alpha and reduced miR-222-3p that targets ER-alpha. MCF-7-A2B1 have activated AKT and Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) that depend on A2B1 expression and are growth inhibited by inhibitors of these pathways.
Target Regulator	Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)		READER	Regulator Info
Target Regulation	Up regulation
Responsed Disease	Breast cancer		ICD-11: 2C60	Disease Info
Pathway Response	MAPK signaling pathway			hsa04010
Pathway Response	PI3K-Akt signaling pathway			hsa04151
Cell Process	Cell migration and invasion
In-vitro Model	HCC1806	Breast squamous cell carcinoma	Homo sapiens	CVCL_1258
	MCF-7	Invasive breast carcinoma	Homo sapiens	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062
	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
	T-47D	Invasive breast carcinoma	Homo sapiens	CVCL_0553

Tamoxifen [Approved]

Drug Info

In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response				[2]
Response Summary	In breast cancer, modest stable overexpression of A2B1 in MCF-7 cells (MCF-7-A2B1 cells) resulted in tamoxifen and fulvestrant - resistance whereas knockdown of A2B1 in LCC9 and LY2 cells restored tamoxifen and fulvestrant, endocrine-sensitivity. MCF-7-A2B1 cells have increased ER-alpha and reduced miR-222-3p that targets ER-alpha. MCF-7-A2B1 have activated AKT and Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1) that depend on A2B1 expression and are growth inhibited by inhibitors of these pathways.
Target Regulator	Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)		READER	Regulator Info
Target Regulation	Up regulation
Responsed Disease	Breast cancer		ICD-11: 2C60	Disease Info
Pathway Response	MAPK signaling pathway			hsa04010
Pathway Response	PI3K-Akt signaling pathway			hsa04151
Cell Process	Cell migration and invasion
In-vitro Model	HCC1806	Breast squamous cell carcinoma	Homo sapiens	CVCL_1258
	MCF-7	Invasive breast carcinoma	Homo sapiens	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062
	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
	T-47D	Invasive breast carcinoma	Homo sapiens	CVCL_0553

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05144		Crosstalk Info
Epigenetic Regulator	Prostate cancer associated transcript 6 (PCAT6)
Regulated Target	Heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1)
Crosstalk relationship	ncRNA → m6A
Disease	Breast cancer	Disease Info
Drug	Tamoxifen	Drug Info
Crosstalk ID: M6ACROT05146		Crosstalk Info
Epigenetic Regulator	Prostate cancer associated transcript 6 (PCAT6)
Regulated Target	Heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1)
Crosstalk relationship	ncRNA → m6A
Disease	Breast cancer	Disease Info
Drug	Fulvestrant	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00327)

Mitogen-activated protein kinase 1 (MAPK/ERK2/MAPK1)

Adenosine-to-Inosine editing (A-to-I)

In total 28 m6A sequence/site(s) in this target gene
mod ID: A2ISITE011083		Click to Show/Hide the Full List
mod site	chr22:21764059-21764060:-		[8]
Sequence	AGAATTTCTTCAGTCCAGAGAATTCCTCCTGGCAGCCCTGT
Transcript ID List	ENST00000215832.10; ENST00000491588.1
External Link	RMBase: RNA-editing_site_91006
mod ID: A2ISITE011084		Click to Show/Hide the Full List
mod site	chr22:21764143-21764144:-		[8]
Sequence	CAGCCCGTCTTGGCTTATCCACTTTGACTCCTTTGAGCCGT
Transcript ID List	ENST00000491588.1; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91007
mod ID: A2ISITE011085		Click to Show/Hide the Full List
mod site	chr22:21769623-21769624:-		[9]
Sequence	CTCAGCCTCCTGAGTAGCTGAGATTATAGGCGTGCACCACC
Transcript ID List	ENST00000544786.1; ENST00000215832.10; ENST00000398822.7
External Link	RMBase: RNA-editing_site_91008
mod ID: A2ISITE011086		Click to Show/Hide the Full List
mod site	chr22:21770222-21770223:-		[9]
Sequence	CCGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCTGG
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91009
mod ID: A2ISITE011087		Click to Show/Hide the Full List
mod site	chr22:21770496-21770497:-		[9]
Sequence	ACCTCCACCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCC
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: RNA-editing_site_91010
mod ID: A2ISITE011088		Click to Show/Hide the Full List
mod site	chr22:21770869-21770870:-		[9]
Sequence	CAGGAGGCAGAGGTTGCAGTAAGCCGGGATCGTACCACTGC
Transcript ID List	ENST00000398822.7; rmsk_5251866; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91011
mod ID: A2ISITE011089		Click to Show/Hide the Full List
mod site	chr22:21777501-21777502:-		[9]
Sequence	GGATTCCATCCTGGGCAACAAAGTGAGACCCTGTCTCAAAA
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1; rmsk_5251876
External Link	RMBase: RNA-editing_site_91012
mod ID: A2ISITE011090		Click to Show/Hide the Full List
mod site	chr22:21789738-21789739:-		[9]
Sequence	ACCTCTGCCTCCTAGGTTCAAGCAATTCTCCTGCCTCTGCC
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: RNA-editing_site_91013
mod ID: A2ISITE011091		Click to Show/Hide the Full List
mod site	chr22:21790589-21790590:-		[9]
Sequence	GCTACTCAGTAGTGCCAGCTACTCAGGACCTGGCTGAGGTG
Transcript ID List	rmsk_5251919; ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91014
mod ID: A2ISITE011092		Click to Show/Hide the Full List
mod site	chr22:21793343-21793344:-		[9]
Sequence	GACAGGGTTTTAACCATGTTAGCCAGGATGGGCTCAACCTC
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91015
mod ID: A2ISITE011093		Click to Show/Hide the Full List
mod site	chr22:21814507-21814508:-		[9]
Sequence	TAAAATTGTTTTGGTTAATTATATGTTTTGGTAAAAAGCAT
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91016
mod ID: A2ISITE011094		Click to Show/Hide the Full List
mod site	chr22:21824675-21824676:-		[9]
Sequence	AGTTTAGGGCTGTTAGGAATAAAGCTCCTACAGACATCTGT
Transcript ID List	ENST00000544786.1; ENST00000215832.10; ENST00000398822.7
External Link	RMBase: RNA-editing_site_91017
mod ID: A2ISITE011095		Click to Show/Hide the Full List
mod site	chr22:21832823-21832824:-		[9]
Sequence	TTTCAACCTGCCCCCAGATAACAGCCACGCCCACAACACTC
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91018
mod ID: A2ISITE011096		Click to Show/Hide the Full List
mod site	chr22:21832824-21832825:-		[9]
Sequence	TTTTCAACCTGCCCCCAGATAACAGCCACGCCCACAACACT
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91019
mod ID: A2ISITE011097		Click to Show/Hide the Full List
mod site	chr22:21833115-21833116:-		[9]
Sequence	CGTGGGTTAGTGTTGTGGGCATGGCTGCTATCTGGGGGCAG
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91020
mod ID: A2ISITE011098		Click to Show/Hide the Full List
mod site	chr22:21833174-21833175:-		[9]
Sequence	GCGAAGACGGCACAAGTTTGAACATTCGTCCTGGAGATCAT
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91021
mod ID: A2ISITE011099		Click to Show/Hide the Full List
mod site	chr22:21833213-21833214:-		[10]
Sequence	CAAATATACTCTATCACTTAAGTAGGTTTTCGGGAGTGAGC
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91022
mod ID: A2ISITE011100		Click to Show/Hide the Full List
mod site	chr22:21833214-21833215:-		[10]
Sequence	TCAAATATACTCTATCACTTAAGTAGGTTTTCGGGAGTGAG
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91023
mod ID: A2ISITE011101		Click to Show/Hide the Full List
mod site	chr22:21844964-21844965:-		[9]
Sequence	AGACGGGATTTCACCCTGTTAGCTAGGATGGTCTCCATCTG
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: RNA-editing_site_91024
mod ID: A2ISITE011102		Click to Show/Hide the Full List
mod site	chr22:21863404-21863405:-		[11]
Sequence	CCGTGGCGGTGTGCGCCTGTAGTCTCAGCTGCTGGGGAGGC
Transcript ID List	rmsk_5252130; ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91025
mod ID: A2ISITE011103		Click to Show/Hide the Full List
mod site	chr22:21863430-21863431:-		[11]
Sequence	AAAATACAAAAAAAAAAAGTAGCCGGCCGTGGCGGTGTGCG
Transcript ID List	ENST00000215832.10; ENST00000398822.7; rmsk_5252130; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91026
mod ID: A2ISITE011104		Click to Show/Hide the Full List
mod site	chr22:21863460-21863461:-		[11]
Sequence	GGCTAACATGGTGAAACCCTATCTCTACTAAAAATACAAAA
Transcript ID List	rmsk_5252130; ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91027
mod ID: A2ISITE011105		Click to Show/Hide the Full List
mod site	chr22:21863465-21863466:-		[11]
Sequence	ATCCTGGCTAACATGGTGAAACCCTATCTCTACTAAAAATA
Transcript ID List	ENST00000215832.10; rmsk_5252130; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: RNA-editing_site_91028
mod ID: A2ISITE011106		Click to Show/Hide the Full List
mod site	chr22:21863545-21863546:-		[11]
Sequence	AGGCGCGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAG
Transcript ID List	rmsk_5252130; ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91029
mod ID: A2ISITE011107		Click to Show/Hide the Full List
mod site	chr22:21864312-21864313:-		[11]
Sequence	GCGTTTTGCCATGTTGGCCAAGATGGTCTCAAACTCCTGAC
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: RNA-editing_site_91030
mod ID: A2ISITE011108		Click to Show/Hide the Full List
mod site	chr22:21864333-21864334:-		[11]
Sequence	TTTTGTATTTTTGTAGAGACAGCGTTTTGCCATGTTGGCCA
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91031
mod ID: A2ISITE011109		Click to Show/Hide the Full List
mod site	chr22:21864374-21864375:-		[11]
Sequence	TGGGACTACAGGCGCGTGCCACCATGCTCAGCTAATTTTTT
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91032
mod ID: A2ISITE011110		Click to Show/Hide the Full List
mod site	chr22:21866247-21866248:-		[11]
Sequence	CTACAGGCGCGCGACACCACGCCCGGCCCATTTTTGTATTT
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: RNA-editing_site_91033

5-methylcytidine (m5C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002874		Click to Show/Hide the Full List
mod site	chr22:21764910-21764911:-
Sequence	TCAACTTCCTTCTTCATCTGCCTGATTGTGAATTTTCTCAG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000215832.10; ENST00000491588.1
External Link	RMBase: m5C_site_30434
mod ID: M5CSITE002875		Click to Show/Hide the Full List
mod site	chr22:21788313-21788314:-
Sequence	CTAGGAACTATTTGCTTTCTCTTCCACACAAAAATAAGGTG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m5C_site_30435

N6-methyladenosine (m6A)

In total 129 m6A sequence/site(s) in this target gene
mod ID: M6ASITE056653		Click to Show/Hide the Full List
mod site	chr22:21755942-21755943:-		[12]
Sequence	GGCAGGCAATGGCTGATAAGACATGAATTTGTAAGGCGATG
Motif Score	2.897386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556847
mod ID: M6ASITE056654		Click to Show/Hide the Full List
mod site	chr22:21758576-21758577:-		[13]
Sequence	CTAGACCCCGCCATGTCCGGACAATGATATAGAGCGTCTCA
Motif Score	3.643047619
Cell/Tissue List	H1B
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556848
mod ID: M6ASITE056655		Click to Show/Hide the Full List
mod site	chr22:21758592-21758593:-		[13]
Sequence	GGTGTGGGCAGTGGTCCTAGACCCCGCCATGTCCGGACAAT
Motif Score	2.876744048
Cell/Tissue List	H1A; H1B
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556849
mod ID: M6ASITE056657		Click to Show/Hide the Full List
mod site	chr22:21758648-21758649:-		[13]
Sequence	GCTGTGGCACGTGGGCGGAGACTGAGTGGCTGGGCATGTGT
Motif Score	3.319380952
Cell/Tissue List	H1B
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556850
mod ID: M6ASITE056658		Click to Show/Hide the Full List
mod site	chr22:21758680-21758681:-		[13]
Sequence	AGGTGGGATGCAACCACAGGACCAGTGGAGGGGCTGTGGCA
Motif Score	3.622404762
Cell/Tissue List	H1B
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556851
mod ID: M6ASITE056659		Click to Show/Hide the Full List
mod site	chr22:21759781-21759782:-		[12]
Sequence	GCTTTCTTCCTCTGCTTCAGACTGTCAGCTGTAAAGTGGAA
Motif Score	3.319380952
Cell/Tissue List	HEK293T; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000215832.10; rmsk_5251854
External Link	RMBase: m6A_site_556852
mod ID: M6ASITE056660		Click to Show/Hide the Full List
mod site	chr22:21759855-21759856:-		[12]
Sequence	CCCATCCAGCTGGGTTCAGAACTACCCCCTGCTTATAACTG
Motif Score	3.373380952
Cell/Tissue List	HEK293T; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_5251854; ENST00000215832.10
External Link	RMBase: m6A_site_556853
mod ID: M6ASITE056661		Click to Show/Hide the Full List
mod site	chr22:21759876-21759877:-		[12]
Sequence	GGAAAGAGCACAGGCCTTGGACCCATCCAGCTGGGTTCAGA
Motif Score	3.622404762
Cell/Tissue List	HEK293T; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_5251854; ENST00000215832.10
External Link	RMBase: m6A_site_556854
mod ID: M6ASITE056662		Click to Show/Hide the Full List
mod site	chr22:21759933-21759934:-		[12]
Sequence	TGTAATGACTTATTTACAAAACAAAGATACTGGAAAATGTT
Motif Score	2.20572619
Cell/Tissue List	HEK293T; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556855
mod ID: M6ASITE056663		Click to Show/Hide the Full List
mod site	chr22:21759983-21759984:-		[12]
Sequence	ATAAAGATAGGATTTCTTGGACATTTGGTTCTTATCAATAT
Motif Score	3.643047619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556856
mod ID: M6ASITE056664		Click to Show/Hide the Full List
mod site	chr22:21760318-21760319:-		[14]
Sequence	GTCCCTGTATTACCAAAATAACACAGCACCGTGCATGTATA
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556857
mod ID: M6ASITE056665		Click to Show/Hide the Full List
mod site	chr22:21760368-21760369:-		[15]
Sequence	ACTTGTAAAAAAAAAAAACTACAAAAAAATCCTTAGAATCA
Motif Score	2.078666667
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556858
mod ID: M6ASITE056666		Click to Show/Hide the Full List
mod site	chr22:21760371-21760372:-		[15]
Sequence	CTGACTTGTAAAAAAAAAAAACTACAAAAAAATCCTTAGAA
Motif Score	2.627720238
Cell/Tissue List	HEK293T; Huh7
Seq Type List	DART-seq; MeRIP-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556859
mod ID: M6ASITE056668		Click to Show/Hide the Full List
mod site	chr22:21760388-21760389:-		[15]
Sequence	TTGAATGTTTATGGCACCTGACTTGTAAAAAAAAAAAACTA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556860
mod ID: M6ASITE056669		Click to Show/Hide the Full List
mod site	chr22:21760526-21760527:-		[15]
Sequence	ATTGTTACAATTTAACATTAACATTTATTTGTGGTATTTGT
Motif Score	2.168095238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556861
mod ID: M6ASITE056670		Click to Show/Hide the Full List
mod site	chr22:21760532-21760533:-		[15]
Sequence	CATTATATTGTTACAATTTAACATTAACATTTATTTGTGGT
Motif Score	2.168095238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556862
mod ID: M6ASITE056671		Click to Show/Hide the Full List
mod site	chr22:21760540-21760541:-		[15]
Sequence	TGTTTATTCATTATATTGTTACAATTTAACATTAACATTTA
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556863
mod ID: M6ASITE056672		Click to Show/Hide the Full List
mod site	chr22:21760639-21760640:-		[15]
Sequence	TGGTGCCTTCTTGGTATTGTACCCCAAAATTCTGCATAGAT
Motif Score	2.8355
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556864
mod ID: M6ASITE056673		Click to Show/Hide the Full List
mod site	chr22:21760664-21760665:-		[15]
Sequence	CTGCTTTGTATCTGCTTTGTACTGTTGGTGCCTTCTTGGTA
Motif Score	3.278136905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556865
mod ID: M6ASITE056674		Click to Show/Hide the Full List
mod site	chr22:21760685-21760686:-		[15]
Sequence	GCACTCAAGAAAGTTCTGAAACTGCTTTGTATCTGCTTTGT
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556866
mod ID: M6ASITE056675		Click to Show/Hide the Full List
mod site	chr22:21760749-21760750:-		[15]
Sequence	TCCAGGGTTGCACCAGGTTTACCTAAAGCTTGTTGCCTTTT
Motif Score	2.052208333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556867
mod ID: M6ASITE056676		Click to Show/Hide the Full List
mod site	chr22:21760758-21760759:-		[15]
Sequence	AGCAAGTCCTCCAGGGTTGCACCAGGTTTACCTAAAGCTTG
Motif Score	2.809946429
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556868
mod ID: M6ASITE056677		Click to Show/Hide the Full List
mod site	chr22:21760794-21760795:-		[14]
Sequence	CTTGACATGATGGGTCAGAAACAAATGGAAATCCAGAGCAA
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556869
mod ID: M6ASITE056679		Click to Show/Hide the Full List
mod site	chr22:21760810-21760811:-		[15]
Sequence	CTCTTACGTCATCCACCTTGACATGATGGGTCAGAAACAAA
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556870
mod ID: M6ASITE056680		Click to Show/Hide the Full List
mod site	chr22:21760825-21760826:-		[15]
Sequence	GTGAATATGTGGTTTCTCTTACGTCATCCACCTTGACATGA
Motif Score	2.046785714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556871
mod ID: M6ASITE056681		Click to Show/Hide the Full List
mod site	chr22:21760848-21760849:-		[15]
Sequence	GGTGCAGATGAGAAGCTATAACAGTGAATATGTGGTTTCTC
Motif Score	2.168095238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556872
mod ID: M6ASITE056682		Click to Show/Hide the Full List
mod site	chr22:21760876-21760877:-		[15]
Sequence	GCTGGTGTTTGAAACATGATACTCCTGTGGTGCAGATGAGA
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556873
mod ID: M6ASITE056683		Click to Show/Hide the Full List
mod site	chr22:21760883-21760884:-		[15]
Sequence	TTGTTATGCTGGTGTTTGAAACATGATACTCCTGTGGTGCA
Motif Score	2.20572619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556874
mod ID: M6ASITE056684		Click to Show/Hide the Full List
mod site	chr22:21760931-21760932:-		[14]
Sequence	TGAGCAATCCTTTTGCTTATACATTTTTAAAGCATTTGTGC
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556875
mod ID: M6ASITE056685		Click to Show/Hide the Full List
mod site	chr22:21761034-21761035:-		[15]
Sequence	GCTTTGGGTCCTTCCATAATACTTTTATATTTGTAAATCAA
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556876
mod ID: M6ASITE056686		Click to Show/Hide the Full List
mod site	chr22:21761076-21761077:-		[15]
Sequence	TATGGTAACAGTATGTTAATACACACATACATACGCACACA
Motif Score	2.110482143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556877
mod ID: M6ASITE056687		Click to Show/Hide the Full List
mod site	chr22:21761089-21761090:-		[15]
Sequence	AACTTTTATATAGTATGGTAACAGTATGTTAATACACACAT
Motif Score	2.168095238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556878
mod ID: M6ASITE056688		Click to Show/Hide the Full List
mod site	chr22:21761108-21761109:-		[15]
Sequence	ATATGGTTTTTAAATTGGTAACTTTTATATAGTATGGTAAC
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556879
mod ID: M6ASITE056690		Click to Show/Hide the Full List
mod site	chr22:21761158-21761159:-		[15]
Sequence	ATTTCAGCCATTCAGAGGAAACTGTTTTCTCTTTATTTGCT
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556880
mod ID: M6ASITE056691		Click to Show/Hide the Full List
mod site	chr22:21761192-21761193:-		[14]
Sequence	CAAAAGTAAACTACCCAACCACATGCCACGTAATATTTCAG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556881
mod ID: M6ASITE056692		Click to Show/Hide the Full List
mod site	chr22:21761248-21761249:-		[14]
Sequence	ACCAGTAGCTTTGAGAAGCTACATGTAGCTCACCAGTGGTT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556882
mod ID: M6ASITE056693		Click to Show/Hide the Full List
mod site	chr22:21761290-21761291:-		[16]
Sequence	CATTCCTTCTGCTCTTGGGCACAGGCAGTGGGTGTAGAGGT
Motif Score	2.830589286
Cell/Tissue List	brain; kidney; liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556883
mod ID: M6ASITE056694		Click to Show/Hide the Full List
mod site	chr22:21761380-21761381:-		[17]
Sequence	AAGCTAGCAGAGATACGCAGACATTGTGGCATCTGGGTAGA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556884
mod ID: M6ASITE056695		Click to Show/Hide the Full List
mod site	chr22:21761386-21761387:-		[15]
Sequence	TCCTCAAAGCTAGCAGAGATACGCAGACATTGTGGCATCTG
Motif Score	2.084416667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556885
mod ID: M6ASITE056696		Click to Show/Hide the Full List
mod site	chr22:21761413-21761414:-		[15]
Sequence	ATCATGAGGACTCTGTCCTGACACAGGTCCTCAAAGCTAGC
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556886
mod ID: M6ASITE056697		Click to Show/Hide the Full List
mod site	chr22:21761424-21761425:-		[17]
Sequence	TGAAAGAACTAATCATGAGGACTCTGTCCTGACACAGGTCC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556887
mod ID: M6ASITE056698		Click to Show/Hide the Full List
mod site	chr22:21761437-21761438:-		[17]
Sequence	AGTGGGATGGAATTGAAAGAACTAATCATGAGGACTCTGTC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556888
mod ID: M6ASITE056699		Click to Show/Hide the Full List
mod site	chr22:21761464-21761465:-		[17]
Sequence	TAGTATAAAAGAAATACTGAACAAGCCAGTGGGATGGAATT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; peripheral-blood
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556889
mod ID: M6ASITE056701		Click to Show/Hide the Full List
mod site	chr22:21761469-21761470:-		[15]
Sequence	TCATTTAGTATAAAAGAAATACTGAACAAGCCAGTGGGATG
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556890
mod ID: M6ASITE056702		Click to Show/Hide the Full List
mod site	chr22:21761503-21761504:-		[17]
Sequence	AGCAAAAAATTCCTGCTGAAACATTCCAGTCCTTTCATTTA
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T; peripheral-blood
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556891
mod ID: M6ASITE056703		Click to Show/Hide the Full List
mod site	chr22:21761553-21761554:-		[17]
Sequence	ATGTTCAAATAAGCTTTCAGACTAATAGCTTTTTTGGTGTC
Motif Score	3.319380952
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556892
mod ID: M6ASITE056704		Click to Show/Hide the Full List
mod site	chr22:21761593-21761594:-		[17]
Sequence	ATTCATATTAGTGACACGGAACAGCACCTCCACTATTTGTA
Motif Score	2.951386905
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556893
mod ID: M6ASITE056705		Click to Show/Hide the Full List
mod site	chr22:21761647-21761648:-		[15]
Sequence	GCATCATTTTGGCTCTTCTTACATTTGTAAAAATGTACAGA
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556894
mod ID: M6ASITE056706		Click to Show/Hide the Full List
mod site	chr22:21761742-21761743:-		[14]
Sequence	CTTTTTATTAATCATGCCAAACATAATGTAACTGGGCAGAG
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T; peripheral-blood
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556895
mod ID: M6ASITE056707		Click to Show/Hide the Full List
mod site	chr22:21761806-21761807:-		[18]
Sequence	TGGAGTCAGATTGGCATGAAACCACTAACTTCATTCTAGAA
Motif Score	2.185083333
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556896
mod ID: M6ASITE056708		Click to Show/Hide the Full List
mod site	chr22:21761872-21761873:-		[14]
Sequence	AACCATATCCTTGGCTACTAACATCTGGAGACTGTGAGCTC
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556897
mod ID: M6ASITE056709		Click to Show/Hide the Full List
mod site	chr22:21761932-21761933:-		[15]
Sequence	TTCTTTTTAAATGGAAAGTTACTATTATAAGGTTAATTTGG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556898
mod ID: M6ASITE056710		Click to Show/Hide the Full List
mod site	chr22:21761960-21761961:-		[15]
Sequence	AAAGCATTGACAGTTTTATTACTCTTGTTTCTTTTTAAATG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556899
mod ID: M6ASITE056712		Click to Show/Hide the Full List
mod site	chr22:21761971-21761972:-		[15]
Sequence	TCATTTATAAAAAAGCATTGACAGTTTTATTACTCTTGTTT
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556900
mod ID: M6ASITE056713		Click to Show/Hide the Full List
mod site	chr22:21762009-21762010:-		[15]
Sequence	AATGTGACTGTTACCGGATAACACTGATTAGTCAGTTTTCA
Motif Score	2.168095238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556901
mod ID: M6ASITE056714		Click to Show/Hide the Full List
mod site	chr22:21762017-21762018:-		[15]
Sequence	GACACAGAAATGTGACTGTTACCGGATAACACTGATTAGTC
Motif Score	2.052208333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556902
mod ID: M6ASITE056715		Click to Show/Hide the Full List
mod site	chr22:21762052-21762053:-		[14]
Sequence	GAGCTGCCGTCTGAAGGTCCACACAGCATTGACGGGACACA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556903
mod ID: M6ASITE056716		Click to Show/Hide the Full List
mod site	chr22:21762120-21762121:-		[14]
Sequence	CATCCTCGGAAAACAGACCCACATCTCTATTCTTGCCCTGA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556904
mod ID: M6ASITE056717		Click to Show/Hide the Full List
mod site	chr22:21762128-21762129:-		[15]
Sequence	AGCTGGCTCATCCTCGGAAAACAGACCCACATCTCTATTCT
Motif Score	2.20572619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556905
mod ID: M6ASITE056718		Click to Show/Hide the Full List
mod site	chr22:21762179-21762180:-		[15]
Sequence	CCACCCAGCCCAGGGTGCTCACGCTCACCACTCCTGTGGCT
Motif Score	2.021232143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556906
mod ID: M6ASITE056719		Click to Show/Hide the Full List
mod site	chr22:21762216-21762217:-		[16]
Sequence	GAGTTGGGAAGGGCCGCCCCACAGTACGCAGTCCTCACCAC
Motif Score	2.053113095
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556907
mod ID: M6ASITE056720		Click to Show/Hide the Full List
mod site	chr22:21762315-21762316:-		[14]
Sequence	ACCCTAACAAAGAAGCCCCGACATCTCAGGTTGGATTCCCT
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556908
mod ID: M6ASITE056721		Click to Show/Hide the Full List
mod site	chr22:21762364-21762365:-		[14]
Sequence	GCTGTCATGTTCCTTTATTCACAATCTTAGGTCTCAAATAT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556909
mod ID: M6ASITE056723		Click to Show/Hide the Full List
mod site	chr22:21762450-21762451:-		[14]
Sequence	CTGGCCCAGCACTTGGATTTACATAAGATGAGTTAGAAAGG
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556910
mod ID: M6ASITE056724		Click to Show/Hide the Full List
mod site	chr22:21762487-21762488:-		[15]
Sequence	CAGAAATGCTCACAGGCCTCACTTTGCCGCCCAGGCACTGG
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556911
mod ID: M6ASITE056725		Click to Show/Hide the Full List
mod site	chr22:21762534-21762535:-		[16]
Sequence	GGATCAGCGTGTCTGAATGGACAGTCAGGTTCAGGTTGTGC
Motif Score	3.643047619
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556912
mod ID: M6ASITE056726		Click to Show/Hide the Full List
mod site	chr22:21762588-21762589:-		[14]
Sequence	AATGTACATCTTCTATCTTCACATTCATGTTAAGATTCAGT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556913
mod ID: M6ASITE056727		Click to Show/Hide the Full List
mod site	chr22:21762603-21762604:-		[15]
Sequence	TAATTCATGAAAATAAATGTACATCTTCTATCTTCACATTC
Motif Score	2.856142857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556914
mod ID: M6ASITE056728		Click to Show/Hide the Full List
mod site	chr22:21762638-21762639:-		[17]
Sequence	AAGACTGCCTGCTAATATGAACAGAAATGCATTTGTAATTC
Motif Score	2.951386905
Cell/Tissue List	HeLa; brain
Seq Type List	m6A-seq; m6A-REF-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556915
mod ID: M6ASITE056729		Click to Show/Hide the Full List
mod site	chr22:21762655-21762656:-		[17]
Sequence	GGAGAATGGGTTATATAAAGACTGCCTGCTAATATGAACAG
Motif Score	3.319380952
Cell/Tissue List	HeLa; A549
Seq Type List	m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556916
mod ID: M6ASITE056730		Click to Show/Hide the Full List
mod site	chr22:21762683-21762684:-		[14]
Sequence	TTTTTCTTGTTTGATTTTTGACAGCAATGGAGAATGGGTTA
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556917
mod ID: M6ASITE056731		Click to Show/Hide the Full List
mod site	chr22:21762776-21762777:-		[15]
Sequence	TTACCTCTGAGTTGTGTTCCACGGAAAATGCTATCCAGCAG
Motif Score	2.027047619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556918
mod ID: M6ASITE056732		Click to Show/Hide the Full List
mod site	chr22:21762805-21762806:-		[17]
Sequence	TGCCTACGATTGAAATGAAAACTCTATTGTTACCTCTGAGT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556919
mod ID: M6ASITE056734		Click to Show/Hide the Full List
mod site	chr22:21762828-21762829:-		[14]
Sequence	GAGATGACTGTCCAAGTGCCACATGCCTACGATTGAAATGA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556920
mod ID: M6ASITE056735		Click to Show/Hide the Full List
mod site	chr22:21762863-21762864:-		[16]
Sequence	TGTACCCTCGCATGACTGTTACAGCTTTCTGTGCAGAGATG
Motif Score	2.07285119
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556921
mod ID: M6ASITE056736		Click to Show/Hide the Full List
mod site	chr22:21762869-21762870:-		[19]
Sequence	AATTACTGTACCCTCGCATGACTGTTACAGCTTTCTGTGCA
Motif Score	3.28175
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556922
mod ID: M6ASITE056737		Click to Show/Hide the Full List
mod site	chr22:21762981-21762982:-		[15]
Sequence	ATTTGTTCCTGCCACTGTGTACTGTGGAGTTGACTCGGTGT
Motif Score	3.278136905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556923
mod ID: M6ASITE056738		Click to Show/Hide the Full List
mod site	chr22:21763069-21763070:-		[17]
Sequence	TTCTGATACTGCTGAGTCAGACTGTCAGAAAAAGCTAGCAC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; HepG2; A549; iSLK
Seq Type List	m6A-seq; DART-seq; MeRIP-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556924
mod ID: M6ASITE056739		Click to Show/Hide the Full List
mod site	chr22:21763126-21763127:-		[15]
Sequence	AAAGCCTCCAGGAGCTCATGACGTGAAGCACTGTTCTGTCC
Motif Score	2.833690476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556925
mod ID: M6ASITE056740		Click to Show/Hide the Full List
mod site	chr22:21763158-21763159:-		[14]
Sequence	ATTTTTCAACCTACAGTATAACAATTTGTAATAAAGCCTCC
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556926
mod ID: M6ASITE056741		Click to Show/Hide the Full List
mod site	chr22:21763166-21763167:-		[16]
Sequence	TCAAGTTCATTTTTCAACCTACAGTATAACAATTTGTAATA
Motif Score	2.078666667
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556927
mod ID: M6ASITE056742		Click to Show/Hide the Full List
mod site	chr22:21763202-21763203:-		[16]
Sequence	ATACAATTCTTTTTCCTTCTACAGCATGTCAGCATCTCAAG
Motif Score	2.078666667
Cell/Tissue List	kidney; HEK293T
Seq Type List	m6A-REF-seq; DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556928
mod ID: M6ASITE056743		Click to Show/Hide the Full List
mod site	chr22:21763247-21763248:-		[14]
Sequence	TGAGGATTTAGCAGAGAGGAACACTGCGTCTTTAAATGAGA
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556929
mod ID: M6ASITE056745		Click to Show/Hide the Full List
mod site	chr22:21763335-21763336:-		[16]
Sequence	ATGTCCCAGGGTGGAACTCCACATGCTGGTGCATATACGCC
Motif Score	2.053113095
Cell/Tissue List	brain; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556930
mod ID: M6ASITE056746		Click to Show/Hide the Full List
mod site	chr22:21763394-21763395:-		[14]
Sequence	CGACATTTGGTGAGAGAAGTACAAAGGTTGCAGTGCTGAGC
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556931
mod ID: M6ASITE056747		Click to Show/Hide the Full List
mod site	chr22:21763445-21763446:-		[14]
Sequence	ACTTAATGTTTGTAAGACTTACAAAAAAAGATTTAAAGTGG
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556932
mod ID: M6ASITE056748		Click to Show/Hide the Full List
mod site	chr22:21763493-21763494:-		[14]
Sequence	TTGTACCATATAGAGGTGTAACACTTGTCAAGAAGCGTTAT
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556933
mod ID: M6ASITE056749		Click to Show/Hide the Full List
mod site	chr22:21763515-21763516:-		[15]
Sequence	ACTCTGTAGTTACTGTGGTCACTTGTACCATATAGAGGTGT
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556934
mod ID: M6ASITE056750		Click to Show/Hide the Full List
mod site	chr22:21763524-21763525:-		[15]
Sequence	AGCAGTGTCACTCTGTAGTTACTGTGGTCACTTGTACCATA
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556935
mod ID: M6ASITE056751		Click to Show/Hide the Full List
mod site	chr22:21763624-21763625:-		[15]
Sequence	TCATATCATGGTAGTCACTAACATATATAAGGTATGTGCTA
Motif Score	2.168095238
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556936
mod ID: M6ASITE056752		Click to Show/Hide the Full List
mod site	chr22:21763654-21763655:-		[15]
Sequence	TCCTTGGGGAGCACTTGTCCACGTCTTTTCTCATATCATGG
Motif Score	2.027047619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556937
mod ID: M6ASITE056753		Click to Show/Hide the Full List
mod site	chr22:21763772-21763773:-		[15]
Sequence	AGTGACAGCCCCTTATTTGCACTTCACCTTTTGACCATAAC
Motif Score	3.252583333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556938
mod ID: M6ASITE056754		Click to Show/Hide the Full List
mod site	chr22:21763893-21763894:-		[15]
Sequence	TTCTACATGATGCCCTGCTGACCATGCAGCCGCACCAGAGA
Motif Score	2.839113095
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000215832.10
External Link	RMBase: m6A_site_556939
mod ID: M6ASITE056756		Click to Show/Hide the Full List
mod site	chr22:21764137-21764138:-		[15]
Sequence	GTCTTGGCTTATCCACTTTGACTCCTTTGAGCCGTTTGGAG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000491588.1; ENST00000215832.10
External Link	RMBase: m6A_site_556940
mod ID: M6ASITE056757		Click to Show/Hide the Full List
mod site	chr22:21764208-21764209:-		[17]
Sequence	AGAGGACTGGACGTGCTCAGACATCGGTGTTCTTCTTCCCA
Motif Score	2.897386905
Cell/Tissue List	HeLa; Jurkat
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10; ENST00000491588.1
External Link	RMBase: m6A_site_556941
mod ID: M6ASITE056758		Click to Show/Hide the Full List
mod site	chr22:21764223-21764224:-		[17]
Sequence	ATAGGACAAGGGCTCAGAGGACTGGACGTGCTCAGACATCG
Motif Score	4.065041667
Cell/Tissue List	HeLa; Jurkat
Seq Type List	m6A-seq
Transcript ID List	ENST00000491588.1; ENST00000215832.10
External Link	RMBase: m6A_site_556942
mod ID: M6ASITE056759		Click to Show/Hide the Full List
mod site	chr22:21764238-21764239:-		[16]
Sequence	TCTGTTTGTGTTTCTATAGGACAAGGGCTCAGAGGACTGGA
Motif Score	3.643047619
Cell/Tissue List	brain; kidney; liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10; ENST00000491588.1
External Link	RMBase: m6A_site_556943
mod ID: M6ASITE056760		Click to Show/Hide the Full List
mod site	chr22:21769213-21769214:-		[16]
Sequence	TGCTAGATTCCAGCCAGGATACAGATCTTAAATTTGTCAGG
Motif Score	2.110482143
Cell/Tissue List	kidney; liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000491588.1; ENST00000544786.1
External Link	RMBase: m6A_site_556944
mod ID: M6ASITE056761		Click to Show/Hide the Full List
mod site	chr22:21769235-21769236:-		[17]
Sequence	AAGAACTAATTTTTGAAGAGACTGCTAGATTCCAGCCAGGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; Jurkat
Seq Type List	m6A-seq
Transcript ID List	ENST00000491588.1; ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: m6A_site_556945
mod ID: M6ASITE056762		Click to Show/Hide the Full List
mod site	chr22:21769251-21769252:-		[17]
Sequence	CCTAAGGAAAAGCTCAAAGAACTAATTTTTGAAGAGACTGC
Motif Score	3.373380952
Cell/Tissue List	HeLa; Jurkat
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000491588.1; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m6A_site_556946
mod ID: M6ASITE056763		Click to Show/Hide the Full List
mod site	chr22:21769291-21769292:-		[16]
Sequence	CGAAGCACCATTCAAGTTCGACATGGAATTGGATGACTTGC
Motif Score	2.865571429
Cell/Tissue List	brain; kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000491588.1; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556947
mod ID: M6ASITE056764		Click to Show/Hide the Full List
mod site	chr22:21772923-21772924:-		[17]
Sequence	CACAAGAGGATTGAAGTAGAACAGGCTCTGGCCCACCCATA
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: m6A_site_556948
mod ID: M6ASITE056765		Click to Show/Hide the Full List
mod site	chr22:21772966-21772967:-		[17]
Sequence	TATAGCTCTGGACTTATTGGACAAAATGTTGACATTCAACC
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m6A_site_556949
mod ID: M6ASITE056767		Click to Show/Hide the Full List
mod site	chr22:21772975-21772976:-		[17]
Sequence	CTTTCTCTTTATAGCTCTGGACTTATTGGACAAAATGTTGA
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556950
mod ID: M6ASITE056768		Click to Show/Hide the Full List
mod site	chr22:21788285-21788286:-		[17]
Sequence	CAAAAATAAGGTGCCATGGAACAGGCTGTTCCCAAATGCTG
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: m6A_site_556951
mod ID: M6ASITE056769		Click to Show/Hide the Full List
mod site	chr22:21788308-21788309:-		[14]
Sequence	AACTATTTGCTTTCTCTTCCACACAAAAATAAGGTGCCATG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: m6A_site_556952
mod ID: M6ASITE056770		Click to Show/Hide the Full List
mod site	chr22:21788327-21788328:-		[17]
Sequence	AATAAATTTAAAAGCTAGGAACTATTTGCTTTCTCTTCCAC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m6A_site_556953
mod ID: M6ASITE056771		Click to Show/Hide the Full List
mod site	chr22:21788360-21788361:-		[17]
Sequence	TGGATCCCCATCACAAGAAGACCTGAATTGTATAATAAATT
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000544786.1; ENST00000215832.10; ENST00000398822.7
External Link	RMBase: m6A_site_556954
mod ID: M6ASITE056772		Click to Show/Hide the Full List
mod site	chr22:21788368-21788369:-		[14]
Sequence	GGTATTCTTGGATCCCCATCACAAGAAGACCTGAATTGTAT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m6A_site_556955
mod ID: M6ASITE056773		Click to Show/Hide the Full List
mod site	chr22:21788701-21788702:-		[14]
Sequence	TTATCTTGACCAGCTGAACCACATTTTGGGTAAGGTTCCCG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: m6A_site_556956
mod ID: M6ASITE056774		Click to Show/Hide the Full List
mod site	chr22:21788704-21788705:-		[17]
Sequence	GCATTATCTTGACCAGCTGAACCACATTTTGGGTAAGGTTC
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: m6A_site_556957
mod ID: M6ASITE056775		Click to Show/Hide the Full List
mod site	chr22:21788803-21788804:-		[14]
Sequence	TCTCTTTCTCCTGCAGGGCTACACCAAGTCCATTGATATTT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m6A_site_556958
mod ID: M6ASITE056776		Click to Show/Hide the Full List
mod site	chr22:21799081-21799082:-		[14]
Sequence	TGCAGATCCAGACCATGATCACACAGGGTTCCTGACAGAAT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: m6A_site_556959
mod ID: M6ASITE056778		Click to Show/Hide the Full List
mod site	chr22:21799090-21799091:-		[17]
Sequence	GGCCCGTGTTGCAGATCCAGACCATGATCACACAGGGTTCC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: m6A_site_556960
mod ID: M6ASITE056779		Click to Show/Hide the Full List
mod site	chr22:21805868-21805869:-		[14]
Sequence	GCCTTCCAACCTGCTGCTCAACACCACCTGTGATCTCAAGG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544786.1; ENST00000398822.7; ENST00000215832.10
External Link	RMBase: m6A_site_556961
mod ID: M6ASITE056780		Click to Show/Hide the Full List
mod site	chr22:21805984-21805985:-		[14]
Sequence	TACAAGCTCTTGAAGACACAACACCTCAGCAATGACCATAT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556962
mod ID: M6ASITE056781		Click to Show/Hide the Full List
mod site	chr22:21805989-21805990:-		[17]
Sequence	ATCTTTACAAGCTCTTGAAGACACAACACCTCAGCAATGAC
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556963
mod ID: M6ASITE056782		Click to Show/Hide the Full List
mod site	chr22:21806013-21806014:-		[17]
Sequence	TAGTACAGGACCTCATGGAAACAGATCTTTACAAGCTCTTG
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10; ENST00000544786.1; ENST00000398822.7
External Link	RMBase: m6A_site_556964
mod ID: M6ASITE056783		Click to Show/Hide the Full List
mod site	chr22:21806024-21806025:-		[17]
Sequence	AAACAGATATATAGTACAGGACCTCATGGAAACAGATCTTT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556965
mod ID: M6ASITE056784		Click to Show/Hide the Full List
mod site	chr22:21807702-21807703:-		[14]
Sequence	GAACATCATTGGAATCAATGACATTATTCGAGCACCAACCA
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544786.1; ENST00000215832.10; ENST00000398822.7
External Link	RMBase: m6A_site_556966
mod ID: M6ASITE056785		Click to Show/Hide the Full List
mod site	chr22:21807720-21807721:-		[17]
Sequence	ACTGCGCTTCAGACATGAGAACATCATTGGAATCAATGACA
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10; ENST00000544786.1
External Link	RMBase: m6A_site_556967
mod ID: M6ASITE056786		Click to Show/Hide the Full List
mod site	chr22:21807728-21807729:-		[17]
Sequence	AAAATCTTACTGCGCTTCAGACATGAGAACATCATTGGAAT
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556968
mod ID: M6ASITE056787		Click to Show/Hide the Full List
mod site	chr22:21807763-21807764:-		[17]
Sequence	ACCAGACCTACTGCCAGAGAACCCTGAGGGAGATAAAAATC
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000215832.10; ENST00000398822.7; ENST00000544786.1
External Link	RMBase: m6A_site_556969
mod ID: M6ASITE056789		Click to Show/Hide the Full List
mod site	chr22:21807778-21807779:-		[17]
Sequence	TCAGCCCCTTTGAGCACCAGACCTACTGCCAGAGAACCCTG
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556970
mod ID: M6ASITE056790		Click to Show/Hide the Full List
mod site	chr22:21807825-21807826:-		[14]
Sequence	CTCTGCTTATGATAATGTCAACAAAGTTCGAGTAGCTATCA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544786.1; ENST00000215832.10; ENST00000398822.7
External Link	RMBase: m6A_site_556971
mod ID: M6ASITE056791		Click to Show/Hide the Full List
mod site	chr22:21867351-21867352:-		[14]
Sequence	GCGCTACACCAACCTCTCGTACATCGGCGAGGGCGCCTACG
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000544786.1; ENST00000215832.10
External Link	RMBase: m6A_site_556972
mod ID: M6ASITE056792		Click to Show/Hide the Full List
mod site	chr22:21867366-21867367:-		[14]
Sequence	GTTCGACGTGGGGCCGCGCTACACCAACCTCTCGTACATCG
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544786.1; ENST00000215832.10; ENST00000398822.7
External Link	RMBase: m6A_site_556973
mod ID: M6ASITE056793		Click to Show/Hide the Full List
mod site	chr22:21867441-21867442:-		[14]
Sequence	CGGCGGCGGCCCGGCAGCCAACATGGCGGCGGCGGCGGCGG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000215832.10; ENST00000398822.7
External Link	RMBase: m6A_site_556974
mod ID: M6ASITE056794		Click to Show/Hide the Full List
mod site	chr22:21867510-21867511:-		[14]
Sequence	CAGTCCCTGCGGGAGGGGCGACAAGAGCTGAGCGGCGGCCG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000398822.7; ENST00000215832.10
External Link	RMBase: m6A_site_556975

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000177		Click to Show/Hide the Full List
mod site	chr22:21762149-21762150:-		[20]
Sequence	CTCCTGTGGCTGAGGAAGGATAGCTGGCTCATCCTCGGAAA
Transcript ID List	ENST00000215832.10
External Link	RMBase: Pseudo_site_3409

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Ref 2	HNRNPA2B1 regulates tamoxifen- and fulvestrant-sensitivity and hallmarks of endocrine resistance in breast cancer cells. Cancer Lett. 2021 Oct 10;518:152-168. doi: 10.1016/j.canlet.2021.07.015. Epub 2021 Jul 14.
Ref 3	Effects of the ABCG2 and ABCB1 drug transporter polymorphisms on the pharmacokinetics of bicalutamide in humans. Clin Chim Acta. 2015 Jan 1;438:7-11. doi: 10.1016/j.cca.2014.08.006. Epub 2014 Aug 11.
Ref 4	In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein. Epilepsia. 2011 Oct;52(10):1894-904.
Ref 5	N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 3 or insulin like growth factor 2 mRNA binding protein 2 knockdown protects human bronchial epithelial cells from hypoxia/reoxygenation injury by inactivating p38 MAPK, AKT, ERK1/2, and NF-KappaB pathways. Bioengineered. 2022 May;13(5):11973-11986. doi: 10.1080/21655979.2021.1999550.
Ref 6	2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4. doi: 10.1038/nrd3657.
Ref 7	The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3279-86. doi: 10.1158/1535-7163.MCT-07-0564. Epub 2007 Dec 7.
Ref 8	Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science. 2009 May 29;324(5931):1210-3. doi: 10.1126/science.1170995.
Ref 9	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 10	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 11	Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res. 2004 Sep;14(9):1719-25. doi: 10.1101/gr.2855504.
Ref 12	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 13	m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 2014 Dec 4;15(6):707-19. doi: 10.1016/j.stem.2014.09.019. Epub 2014 Oct 16.
Ref 14	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 15	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 16	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 17	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 18	R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
Ref 19	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 20	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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