m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00271)

Target Name	Hepatoma-derived growth factor (HDGF)
Synonyms	HDGF; High mobility group protein 1-like 2; HMG-1L2; HMG1L2 Click to Show/Hide
Gene Name	HDGF
Chromosomal Location	1q23.1
Family	HDGF family
Function	[Isoform 1]: Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. [Isoform 2]: Does not have mitogenic activity for fibroblasts. Does not bind heparin. [Isoform 3]: Has mitogenic activity for fibroblasts. Heparin-binding protein. Click to Show/Hide
Gene ID	3068
Uniprot ID	HDGF_HUMAN
HGNC ID	HGNC:4856
KEGG ID	hsa:3068

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

HDGF can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	LX2 cell line	Homo sapiens
Treatment: shMETTL3 LX2 cells Control: shLuc LX2 cells		GSE207909
Regulation		logFC: -6.20E-01 p-value: 6.85E-14
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between HDGF and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 1.03E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	Elevated METTL3 expression promotes tumour angiogenesis and glycolysis in Gastric cancer. P300-mediated H3K27 acetylation activation in the promoter of METTL3 induced METTL3 transcription, which stimulated m6A modification of Hepatoma-derived growth factor (HDGF) mRNA, and the m6A reader IGF2BP3 then directly recognised and bound to the m6A site on HDGF mRNA and enhanced HDGF mRNA stability.
Target Regulation	Up regulation
Responsed Disease	Gastric cancer		ICD-11: 2B72	Disease Info
Pathway Response	Glycolysis / Gluconeogenesis			hsa00010
Cell Process	Glycolysis
In-vitro Model	HGC-27	Gastric carcinoma	Homo sapiens	CVCL_1279
	NCI-N87	Gastric tubular adenocarcinoma	Homo sapiens	CVCL_1603
	SGC-7901	Gastric carcinoma	Homo sapiens	CVCL_0520
In-vivo Model	Mice 8 weeks after splenic portal vein injection of BGC823 cells with METTL3 overexpression or vector-transfected cells.

Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) [READER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by IGF2BP3*
Cell Line	ES-2 cell line	Homo sapiens
Treatment: siIGF2BP3 ES-2 cells Control: siControl ES-2 cells		GSE109604
Regulation		logFC: -6.81E-01 p-value: 1.47E-02
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	Elevated METTL3 expression promotes tumour angiogenesis and glycolysis in Gastric cancer. P300-mediated H3K27 acetylation activation in the promoter of METTL3 induced METTL3 transcription, which stimulated m6A modification of Hepatoma-derived growth factor (HDGF) mRNA, and the m6A reader IGF2BP3 then directly recognised and bound to the m6A site on HDGF mRNA and enhanced HDGF mRNA stability.
Target Regulation	Up regulation
Responsed Disease	Gastric cancer		ICD-11: 2B72	Disease Info
Pathway Response	Glycolysis / Gluconeogenesis			hsa00010
Cell Process	Glycolysis
In-vitro Model	HGC-27	Gastric carcinoma	Homo sapiens	CVCL_1279
	NCI-N87	Gastric tubular adenocarcinoma	Homo sapiens	CVCL_1603
	SGC-7901	Gastric carcinoma	Homo sapiens	CVCL_0520
In-vivo Model	Mice 8 weeks after splenic portal vein injection of BGC823 cells with METTL3 overexpression or vector-transfected cells.

Gastric cancer [ICD-11: 2B72]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	Elevated METTL3 expression promotes tumour angiogenesis and glycolysis in Gastric cancer. P300-mediated H3K27 acetylation activation in the promoter of METTL3 induced METTL3 transcription, which stimulated m6A modification of Hepatoma-derived growth factor (HDGF) mRNA, and the m6A reader IGF2BP3 then directly recognised and bound to the m6A site on HDGF mRNA and enhanced HDGF mRNA stability.
Responsed Disease	Gastric cancer [ICD-11: 2B72]
Target Regulator	Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)		READER	Regulator Info
Target Regulation	Up regulation
Pathway Response	Glycolysis / Gluconeogenesis			hsa00010
Cell Process	Glycolysis
In-vitro Model	HGC-27	Gastric carcinoma	Homo sapiens	CVCL_1279
	NCI-N87	Gastric tubular adenocarcinoma	Homo sapiens	CVCL_1603
	SGC-7901	Gastric carcinoma	Homo sapiens	CVCL_0520
In-vivo Model	Mice 8 weeks after splenic portal vein injection of BGC823 cells with METTL3 overexpression or vector-transfected cells.
Experiment 2 Reporting the m6A-centered Disease Response				[1]
Response Summary	Elevated METTL3 expression promotes tumour angiogenesis and glycolysis in Gastric cancer. P300-mediated H3K27 acetylation activation in the promoter of METTL3 induced METTL3 transcription, which stimulated m6A modification of Hepatoma-derived growth factor (HDGF) mRNA, and the m6A reader IGF2BP3 then directly recognised and bound to the m6A site on HDGF mRNA and enhanced HDGF mRNA stability.
Responsed Disease	Gastric cancer [ICD-11: 2B72]
Target Regulator	Methyltransferase-like 3 (METTL3)		WRITER	Regulator Info
Target Regulation	Up regulation
Pathway Response	Glycolysis / Gluconeogenesis			hsa00010
Cell Process	Glycolysis
In-vitro Model	HGC-27	Gastric carcinoma	Homo sapiens	CVCL_1279
	NCI-N87	Gastric tubular adenocarcinoma	Homo sapiens	CVCL_1603
	SGC-7901	Gastric carcinoma	Homo sapiens	CVCL_0520
In-vivo Model	Mice 8 weeks after splenic portal vein injection of BGC823 cells with METTL3 overexpression or vector-transfected cells.

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

RNA modification

m6A Regulator: ELAV-like protein 1 (ELAVL1)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT00073		Crosstalk Info
Epigenetic Regulator	Y-box-binding protein 1 (YBX1)
Regulated Target	Hepatoma-derived growth factor (HDGF)
Crosstalk relationship	m5C → m6A
Disease	Bladder cancer	Disease Info
Crosstalk ID: M6ACROT00074		Crosstalk Info
Epigenetic Regulator	RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2)
Regulated Target	Hepatoma-derived growth factor (HDGF)
Crosstalk relationship	m5C → m6A
Disease	Bladder cancer	Disease Info

Histone modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03645		Crosstalk Info
Epigenetic Regulator	Histone-lysine N-methyltransferase EZH2 (EZH2)
Regulated Target	Histone H3 lysine 27 trimethylation (H3K27me3)
Crosstalk relationship	Histone modification → m6A
Disease	Gastric cancer	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00271)

Hepatoma-derived growth factor (HDGF)

2'-O-Methylation (2'-O-Me)

In total 5 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000281		Click to Show/Hide the Full List
mod site	chr1:156743862-156743863:-		[3]
Sequence	CCTAGGACTCTCCTAAACGTCCCAAGGAGGCAGAAAACCCT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000537739.5; ENST00000477306.1; ENST00000465180.5; ENST00000357325.10; ENST00000482651.5; ENST00000471377.5; ENST00000495212.1; ENST00000368206.5; ENST00000368209.9; ENST00000469145.5
External Link	RMBase: Nm_site_399
mod ID: 2OMSITE000283		Click to Show/Hide the Full List
mod site	chr1:156743864-156743865:-		[3]
Sequence	TGCCTAGGACTCTCCTAAACGTCCCAAGGAGGCAGAAAACC
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000357325.10; ENST00000495212.1; ENST00000368206.5; ENST00000482651.5; ENST00000469145.5; ENST00000477306.1; ENST00000537739.5; ENST00000471377.5; ENST00000465180.5; ENST00000368209.9
External Link	RMBase: Nm_site_401
mod ID: 2OMSITE000279		Click to Show/Hide the Full List
mod site	chr1:156742188-156742189:-		[3]
Sequence	CTTGGGCTCTGATGAAAAATTGCTGACTGTAGCTTTGGAAG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000368209.9; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: Nm_site_397
mod ID: 2OMSITE000280		Click to Show/Hide the Full List
mod site	chr1:156742733-156742734:-		[3]
Sequence	CTGAGACCTGAAGGGTTGACTTTACCCATTTGGGTGGGAGT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000465180.5; ENST00000537739.5; ENST00000357325.10; ENST00000368209.9
External Link	RMBase: Nm_site_398
mod ID: 2OMSITE000282		Click to Show/Hide the Full List
mod site	chr1:156743863-156743864:-		[3]
Sequence	GCCTAGGACTCTCCTAAACGTCCCAAGGAGGCAGAAAACCC
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000465180.5; ENST00000357325.10; ENST00000537739.5; ENST00000469145.5; ENST00000471377.5; ENST00000482651.5; ENST00000368206.5; ENST00000495212.1
External Link	RMBase: Nm_site_400

5-methylcytidine (m5C)

In total 8 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004198		Click to Show/Hide the Full List
mod site	chr1:156742963-156742964:-		[4]
Sequence	GGGCAGCACAGGAGGGCGGCCTCCTTCTGAGCTCCTGTCCC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m5C_site_4010
mod ID: M5CSITE004199		Click to Show/Hide the Full List
mod site	chr1:156743365-156743366:-		[5]
Sequence	AACTGGCCATGGCCTGCAAACTGGGAACCCCTTTCCCACCC
Cell/Tissue List	HEK293T; HeLa; T24
Seq Type List	Bisulfite-seq; m5C-RIP-seq
Transcript ID List	ENST00000465180.5; ENST00000368209.9; ENST00000477306.1; ENST00000357325.10; ENST00000537739.5; ENST00000482651.5; ENST00000368206.5
External Link	RMBase: m5C_site_4011
mod ID: M5CSITE004200		Click to Show/Hide the Full List
mod site	chr1:156744157-156744158:-		[4]
Sequence	AGGGGACTTGCTGGAGGTAACTGCTGCCTGCCCAGGGCCTG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000368209.9; ENST00000495212.1; ENST00000471377.5; ENST00000465180.5; ENST00000537739.5; ENST00000477306.1; ENST00000482651.5; ENST00000368206.5; ENST00000357325.10; ENST00000469145.5
External Link	RMBase: m5C_site_4012
mod ID: M5CSITE004201		Click to Show/Hide the Full List
mod site	chr1:156745104-156745105:-		[4]
Sequence	CCTCTTCCCTTACGAGGAATCCAAGGAGAAGTTTGGCAAGC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000495212.1; ENST00000537739.5; ENST00000368206.5; ENST00000469145.5; ENST00000471377.5; ENST00000357325.10; ENST00000465180.5; ENST00000368209.9; ENST00000482651.5
External Link	RMBase: m5C_site_4013
mod ID: M5CSITE004202		Click to Show/Hide the Full List
mod site	chr1:156751433-156751434:-		[5]
Sequence	AGCCCGGGGCGCCCGGAGCCCCGCCATGTCGCGATCCAACC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000537739.5; ENST00000357325.10; ENST00000495212.1; ENST00000469145.5; ENST00000465180.5; ENST00000368206.5; ENST00000471377.5; ENST00000368209.9
External Link	RMBase: m5C_site_4014
mod ID: M5CSITE004203		Click to Show/Hide the Full List
mod site	chr1:156751434-156751435:-		[5]
Sequence	GAGCCCGGGGCGCCCGGAGCCCCGCCATGTCGCGATCCAAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000471377.5; ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000495212.1; ENST00000357325.10; ENST00000469145.5; ENST00000368206.5
External Link	RMBase: m5C_site_4015
mod ID: M5CSITE004204		Click to Show/Hide the Full List
mod site	chr1:156751435-156751436:-		[5]
Sequence	GGAGCCCGGGGCGCCCGGAGCCCCGCCATGTCGCGATCCAA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000368206.5; ENST00000471377.5; ENST00000469145.5; ENST00000495212.1; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m5C_site_4016
mod ID: M5CSITE004205		Click to Show/Hide the Full List
mod site	chr1:156751444-156751445:-		[5]
Sequence	GCCCGGCGCGGAGCCCGGGGCGCCCGGAGCCCCGCCATGTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000357325.10; ENST00000465180.5; ENST00000537739.5; ENST00000495212.1; ENST00000368206.5; ENST00000469145.5; ENST00000471377.5; ENST00000368209.9
External Link	RMBase: m5C_site_4017

N6-methyladenosine (m6A)

In total 52 m6A sequence/site(s) in this target gene
mod ID: M6ASITE061011		Click to Show/Hide the Full List
mod site	chr1:156742122-156742123:-		[6]
Sequence	TTCAGTTCTAGGAAAATAAAACCCGTTGATTACTATATTGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000357325.10
External Link	RMBase: m6A_site_59031
mod ID: M6ASITE061022		Click to Show/Hide the Full List
mod site	chr1:156742154-156742155:-		[6]
Sequence	TTGGAAGTTTAGCTCTGAGAACCGTAGATGATTTCAGTTCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59032
mod ID: M6ASITE061033		Click to Show/Hide the Full List
mod site	chr1:156742183-156742184:-		[7]
Sequence	GCTCTGATGAAAAATTGCTGACTGTAGCTTTGGAAGTTTAG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000357325.10; ENST00000537739.5; ENST00000368209.9
External Link	RMBase: m6A_site_59033
mod ID: M6ASITE061044		Click to Show/Hide the Full List
mod site	chr1:156742300-156742301:-		[6]
Sequence	ATTTGTAACCCACTGAGAGGACAGAGAGAAATAAGTGCCCT
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59034
mod ID: M6ASITE061055		Click to Show/Hide the Full List
mod site	chr1:156742362-156742363:-		[7]
Sequence	TCCAGTGTCATTTCTCATCCACATACCCTGACCTGGCCCCC
Motif Score	2.053113095
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000357325.10; ENST00000537739.5; ENST00000368209.9
External Link	RMBase: m6A_site_59035
mod ID: M6ASITE061066		Click to Show/Hide the Full List
mod site	chr1:156742416-156742417:-		[7]
Sequence	CTTCTATTTGGGGCTTGATGACTTTCTTTTTGTAGCTGGGG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000368209.9; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59036
mod ID: M6ASITE061077		Click to Show/Hide the Full List
mod site	chr1:156742535-156742536:-		[7]
Sequence	GTTTTTAATAAAAGAAAATTACAAAAAAAAATTTTAAAGAC
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000465180.5; ENST00000357325.10; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59037
mod ID: M6ASITE061086		Click to Show/Hide the Full List
mod site	chr1:156742571-156742572:-		[7]
Sequence	CCAGACATAAAGGAAAAGACACATTTTTTAGGAAATGTTTT
Motif Score	2.084928571
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537739.5; ENST00000465180.5; ENST00000357325.10; ENST00000368209.9
External Link	RMBase: m6A_site_59038
mod ID: M6ASITE061087		Click to Show/Hide the Full List
mod site	chr1:156742573-156742574:-		[7]
Sequence	ACCCAGACATAAAGGAAAAGACACATTTTTTAGGAAATGTT
Motif Score	2.897386905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000357325.10; ENST00000465180.5
External Link	RMBase: m6A_site_59039
mod ID: M6ASITE061088		Click to Show/Hide the Full List
mod site	chr1:156742587-156742588:-		[7]
Sequence	TAGTCATATATATCACCCAGACATAAAGGAAAAGACACATT
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000465180.5; ENST00000368209.9; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59040
mod ID: M6ASITE061089		Click to Show/Hide the Full List
mod site	chr1:156742630-156742631:-		[7]
Sequence	AGCTGTCCTTTTTCCTCTCCACACAGTGCTCAAGGCCAGCT
Motif Score	2.053113095
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000368209.9; ENST00000465180.5; ENST00000357325.10; ENST00000537739.5
External Link	RMBase: m6A_site_59041
mod ID: M6ASITE061090		Click to Show/Hide the Full List
mod site	chr1:156742677-156742678:-		[8]
Sequence	CCCTTTAGATCTCTGAAGCCACAAATAGGATGCTTGGGAAG
Motif Score	2.053113095
Cell/Tissue List	brain; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000357325.10; ENST00000465180.5; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59042
mod ID: M6ASITE061091		Click to Show/Hide the Full List
mod site	chr1:156742735-156742736:-		[7]
Sequence	ACCTGAGACCTGAAGGGTTGACTTTACCCATTTGGGTGGGA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m6A_site_59043
mod ID: M6ASITE061092		Click to Show/Hide the Full List
mod site	chr1:156742848-156742849:-		[9]
Sequence	TAAATCCTTGATGATTGACAACACCCATTTTTCCTTTTGCC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5; ENST00000465180.5
External Link	RMBase: m6A_site_59044
mod ID: M6ASITE061093		Click to Show/Hide the Full List
mod site	chr1:156742851-156742852:-		[9]
Sequence	CCATAAATCCTTGATGATTGACAACACCCATTTTTCCTTTT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000368209.9; ENST00000465180.5; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59045
mod ID: M6ASITE061094		Click to Show/Hide the Full List
mod site	chr1:156742897-156742898:-		[10]
Sequence	CTAGATTCAGGGAAAGTGGGACAGCTTGTAGGGGAGGGGCT
Motif Score	3.643047619
Cell/Tissue List	HepG2; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000465180.5; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59046
mod ID: M6ASITE061095		Click to Show/Hide the Full List
mod site	chr1:156742937-156742938:-		[9]
Sequence	CTGAGCTCCTGTCCCCTGCTACACCTATTATCCCAGCTGCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000357325.10; ENST00000465180.5
External Link	RMBase: m6A_site_59047
mod ID: M6ASITE061096		Click to Show/Hide the Full List
mod site	chr1:156743084-156743085:-		[6]
Sequence	CACTCTCCTAGGCATTCTGGACCTCTGGGTTGGGATCAGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; H1A; H1B; MT4; A549; peripheral-blood; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000465180.5; ENST00000357325.10; ENST00000537739.5; ENST00000368209.9
External Link	RMBase: m6A_site_59048
mod ID: M6ASITE061097		Click to Show/Hide the Full List
mod site	chr1:156743116-156743117:-		[8]
Sequence	ACAACTGCTCCCACCTCCTGACACCCTTCTCCCACTCTCCT
Motif Score	2.859755952
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000465180.5; ENST00000357325.10
External Link	RMBase: m6A_site_59049
mod ID: M6ASITE061098		Click to Show/Hide the Full List
mod site	chr1:156743136-156743137:-		[6]
Sequence	GGCTTCTGCTGGGGCCTGGGACAACTGCTCCCACCTCCTGA
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T; HepG2; MT4; peripheral-blood; endometrial; NB4; MM6
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5; ENST00000465180.5
External Link	RMBase: m6A_site_59050
mod ID: M6ASITE061099		Click to Show/Hide the Full List
mod site	chr1:156743321-156743322:-		[7]
Sequence	CCTGCTCTCCTCTTCTACTCACTTTTCCCACTCCAAGCCCA
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000482651.5; ENST00000357325.10; ENST00000477306.1; ENST00000465180.5
External Link	RMBase: m6A_site_59051
mod ID: M6ASITE061100		Click to Show/Hide the Full List
mod site	chr1:156743359-156743360:-		[6]
Sequence	CCATGGCCTGCAAACTGGGAACCCCTTTCCCACCCCAACCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000368206.5; ENST00000482651.5; ENST00000357325.10; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m6A_site_59052
mod ID: M6ASITE061101		Click to Show/Hide the Full List
mod site	chr1:156743366-156743367:-		[6]
Sequence	AAACTGGCCATGGCCTGCAAACTGGGAACCCCTTTCCCACC
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000357325.10; ENST00000477306.1; ENST00000368206.5; ENST00000482651.5
External Link	RMBase: m6A_site_59053
mod ID: M6ASITE061102		Click to Show/Hide the Full List
mod site	chr1:156743384-156743385:-		[6]
Sequence	GTCTGGGTGCTACTGGGGAAACTGGCCATGGCCTGCAAACT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000477306.1; ENST00000357325.10; ENST00000482651.5; ENST00000537739.5; ENST00000465180.5; ENST00000368206.5
External Link	RMBase: m6A_site_59054
mod ID: M6ASITE061103		Click to Show/Hide the Full List
mod site	chr1:156743393-156743394:-		[7]
Sequence	CCTGCTGCTGTCTGGGTGCTACTGGGGAAACTGGCCATGGC
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000477306.1; ENST00000368206.5; ENST00000537739.5; ENST00000465180.5; ENST00000482651.5
External Link	RMBase: m6A_site_59055
mod ID: M6ASITE061104		Click to Show/Hide the Full List
mod site	chr1:156743528-156743529:-		[6]
Sequence	AGGGTGGGCTCTCCTAGGAGACCGGCACTGGCTGGGGCAAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000482651.5; ENST00000368206.5; ENST00000477306.1; ENST00000357325.10
External Link	RMBase: m6A_site_59056
mod ID: M6ASITE061105		Click to Show/Hide the Full List
mod site	chr1:156743608-156743609:-		[6]
Sequence	TGGCAGCTGGACTAGGGGGGACCGGCCACTCTCGGAGAAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; U2OS; HEK293T; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000477306.1; ENST00000465180.5; ENST00000482651.5; ENST00000368206.5; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59057
mod ID: M6ASITE061106		Click to Show/Hide the Full List
mod site	chr1:156743618-156743619:-		[6]
Sequence	CCTGACCCCTTGGCAGCTGGACTAGGGGGGACCGGCCACTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; U2OS; HEK293T; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000368206.5; ENST00000537739.5; ENST00000357325.10; ENST00000465180.5; ENST00000482651.5
External Link	RMBase: m6A_site_59058
mod ID: M6ASITE061107		Click to Show/Hide the Full List
mod site	chr1:156743846-156743847:-		[6]
Sequence	ACGTCCCAAGGAGGCAGAAAACCCTGAAGGAGAGGAGAAGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000357325.10; ENST00000465180.5; ENST00000469145.5; ENST00000368206.5; ENST00000482651.5; ENST00000471377.5; ENST00000495212.1; ENST00000537739.5
External Link	RMBase: m6A_site_59059
mod ID: M6ASITE061108		Click to Show/Hide the Full List
mod site	chr1:156744172-156744173:-		[6]
Sequence	GTTGAAGAGGAGAGCAGGGGACTTGCTGGAGGTAACTGCTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000471377.5; ENST00000482651.5; ENST00000469145.5; ENST00000465180.5; ENST00000537739.5; ENST00000477306.1; ENST00000357325.10; ENST00000495212.1; ENST00000368206.5
External Link	RMBase: m6A_site_59060
mod ID: M6ASITE061109		Click to Show/Hide the Full List
mod site	chr1:156744250-156744251:-		[7]
Sequence	GAATGCAGAGGGCAGCAGCGACGAGGAAGGGAAGCTGGTCA
Motif Score	2.839505952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000471377.5; ENST00000368206.5; ENST00000368209.9; ENST00000357325.10; ENST00000537739.5; ENST00000495212.1; ENST00000465180.5; ENST00000482651.5; ENST00000477306.1; ENST00000469145.5
External Link	RMBase: m6A_site_59061
mod ID: M6ASITE061110		Click to Show/Hide the Full List
mod site	chr1:156744312-156744313:-		[6]
Sequence	AGCTGTGTGGAAGAGCCTGAACCAGAGCCCGAAGCTGCAGA
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; U2OS; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000469145.5; ENST00000482651.5; ENST00000357325.10; ENST00000465180.5; ENST00000537739.5; ENST00000495212.1; ENST00000368206.5; ENST00000471377.5
External Link	RMBase: m6A_site_59062
mod ID: M6ASITE061111		Click to Show/Hide the Full List
mod site	chr1:156745038-156745039:-		[6]
Sequence	GGGGCTGTGGGAGATCGAGAACAACCCTACTGTCAAGGCTT
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; HepG2; hESC-HEK293T; U2OS; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000465180.5; ENST00000368209.9; ENST00000482651.5; ENST00000469145.5; ENST00000537739.5; ENST00000471377.5; ENST00000495212.1; ENST00000368206.5; ENST00000357325.10
External Link	RMBase: m6A_site_59063
mod ID: M6ASITE061112		Click to Show/Hide the Full List
mod site	chr1:156745080-156745081:-		[8]
Sequence	GGAGAAGTTTGGCAAGCCCAACAAGAGGAAAGGGTTCAGCG
Motif Score	2.173910714
Cell/Tissue List	brain; kidney; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000368209.9; ENST00000482651.5; ENST00000368206.5; ENST00000495212.1; ENST00000357325.10; ENST00000465180.5; ENST00000469145.5; ENST00000537739.5; ENST00000471377.5
External Link	RMBase: m6A_site_59064
mod ID: M6ASITE061113		Click to Show/Hide the Full List
mod site	chr1:156745125-156745126:-		[6]
Sequence	GGCATTCCTGGGCCCCAAAGACCTCTTCCCTTACGAGGAAT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; U2OS; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000465180.5; ENST00000537739.5; ENST00000357325.10; ENST00000368206.5; ENST00000482651.5; ENST00000368209.9; ENST00000471377.5; ENST00000495212.1; ENST00000469145.5
External Link	RMBase: m6A_site_59065
mod ID: M6ASITE061114		Click to Show/Hide the Full List
mod site	chr1:156745250-156745251:-		[11]
Sequence	GTCGGGAGGGCCCCGGGAGGACTACTCTGGGGAAGGTGAGG
Motif Score	4.065041667
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000482651.5; ENST00000537739.5; ENST00000495212.1; ENST00000368206.5; ENST00000465180.5; ENST00000357325.10; ENST00000368209.9; ENST00000469145.5; ENST00000471377.5
External Link	RMBase: m6A_site_59066
mod ID: M6ASITE061115		Click to Show/Hide the Full List
mod site	chr1:156745306-156745307:-		[12]
Sequence	ACCAAGTCTTTTTTTTCGGGACCCACGAGACGTGAGTGGAG
Motif Score	3.622404762
Cell/Tissue List	MT4; A549; MM6; Huh7
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000368206.5; ENST00000471377.5; ENST00000469145.5; ENST00000357325.10; ENST00000368209.9; ENST00000495212.1; ENST00000482651.5; ENST00000537739.5; ENST00000465180.5
External Link	RMBase: m6A_site_59067
mod ID: M6ASITE061116		Click to Show/Hide the Full List
mod site	chr1:156745332-156745333:-		[9]
Sequence	TGCCGTGAAATCAACAGCCAACAAATACCAAGTCTTTTTTT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000495212.1; ENST00000465180.5; ENST00000482651.5; ENST00000537739.5; ENST00000357325.10; ENST00000471377.5; ENST00000368206.5; ENST00000469145.5; ENST00000368209.9
External Link	RMBase: m6A_site_59068
mod ID: M6ASITE061117		Click to Show/Hide the Full List
mod site	chr1:156747458-156747459:-		[10]
Sequence	CCCAGGCGTCCTGGCTGAGGACCGACTCCTCTGTCCCTGCT
Motif Score	3.622404762
Cell/Tissue List	HepG2; U2OS; MT4; A549; MM6; Huh7; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000465180.5; ENST00000471377.5; ENST00000482651.5; ENST00000368206.5; ENST00000495212.1; ENST00000469145.5; ENST00000537739.5
External Link	RMBase: m6A_site_59069
mod ID: M6ASITE061118		Click to Show/Hide the Full List
mod site	chr1:156751355-156751356:-		[7]
Sequence	CAAGATGAAGGGCTACCCACACTGGCCGGCCCGGGTGAGCA
Motif Score	2.506922619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000471377.5; ENST00000357325.10; ENST00000495212.1; ENST00000368206.5; ENST00000368209.9; ENST00000537739.5; ENST00000469145.5; ENST00000465180.5
External Link	RMBase: m6A_site_59070
mod ID: M6ASITE061119		Click to Show/Hide the Full List
mod site	chr1:156751357-156751358:-		[9]
Sequence	GCCAAGATGAAGGGCTACCCACACTGGCCGGCCCGGGTGAG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000465180.5; ENST00000357325.10; ENST00000469145.5; ENST00000471377.5; ENST00000495212.1; ENST00000368206.5; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59071
mod ID: M6ASITE061120		Click to Show/Hide the Full List
mod site	chr1:156751388-156751389:-		[13]
Sequence	GAAGGAGTACAAATGCGGGGACCTGGTGTTCGCCAAGATGA
Motif Score	3.622404762
Cell/Tissue List	A549; HepG2; U2OS; MT4; MM6; Huh7; NB4
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000537739.5; ENST00000469145.5; ENST00000368209.9; ENST00000368206.5; ENST00000357325.10; ENST00000471377.5; ENST00000465180.5; ENST00000495212.1
External Link	RMBase: m6A_site_59072
mod ID: M6ASITE061121		Click to Show/Hide the Full List
mod site	chr1:156751400-156751401:-		[9]
Sequence	ATCCAACCGGCAGAAGGAGTACAAATGCGGGGACCTGGTGT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000495212.1; ENST00000471377.5; ENST00000357325.10; ENST00000368206.5; ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000469145.5
External Link	RMBase: m6A_site_59073
mod ID: M6ASITE061122		Click to Show/Hide the Full List
mod site	chr1:156751484-156751485:-		[6]
Sequence	CGCCACCGCCGCACGCGCAAACTTGGGCTCGCGCTTCCCGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HepG2; A549; U2OS; MM6; Jurkat; GSC-11; HEK293T; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000469145.5; ENST00000465180.5; ENST00000537739.5; ENST00000471377.5; ENST00000368206.5; ENST00000368209.9; ENST00000495212.1
External Link	RMBase: m6A_site_59074
mod ID: M6ASITE061123		Click to Show/Hide the Full List
mod site	chr1:156751662-156751663:-		[14]
Sequence	TTGAATTTCAAACACAAACAACTGCACGAGCGCGCACCCAC
Motif Score	2.595904762
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000465180.5; ENST00000368206.5; ENST00000357325.10; ENST00000471377.5; ENST00000368209.9
External Link	RMBase: m6A_site_59075
mod ID: M6ASITE061124		Click to Show/Hide the Full List
mod site	chr1:156751665-156751666:-		[6]
Sequence	CAATTGAATTTCAAACACAAACAACTGCACGAGCGCGCACC
Motif Score	2.20572619
Cell/Tissue List	HeLa; A549; hESC-HEK293T; HepG2; U2OS; H1A; H1B; hESCs; fibroblasts; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000368206.5; ENST00000465180.5; ENST00000368209.9; ENST00000357325.10; ENST00000471377.5
External Link	RMBase: m6A_site_59076
mod ID: M6ASITE061125		Click to Show/Hide the Full List
mod site	chr1:156751671-156751672:-		[6]
Sequence	AGGGAGCAATTGAATTTCAAACACAAACAACTGCACGAGCG
Motif Score	2.20572619
Cell/Tissue List	HeLa; A549; hESC-HEK293T; HepG2; U2OS; H1A; H1B; hESCs; fibroblasts; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000368206.5; ENST00000357325.10; ENST00000471377.5; ENST00000465180.5; ENST00000368209.9
External Link	RMBase: m6A_site_59077
mod ID: M6ASITE061126		Click to Show/Hide the Full List
mod site	chr1:156752080-156752081:-		[6]
Sequence	GGAGCAGAGGGCAGGCGGAAACCGTGTACAGACGTCCACAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; A549; HepG2; U2OS; H1A; H1B; hESCs; HEK293T; fibroblasts; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000368206.5; ENST00000471377.5; ENST00000465180.5
External Link	RMBase: m6A_site_59078
mod ID: M6ASITE061127		Click to Show/Hide the Full List
mod site	chr1:156752136-156752137:-		[6]
Sequence	CGCCTAGCACGCTGCCAAGAACCGCGGGTGCCCAGTAAATA
Motif Score	2.930744048
Cell/Tissue List	HeLa; A549; H1B; H1A; H1299; peripheral-blood; GSC-11; HEK293A-TOA; MSC; iSLK; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_276152; ENST00000471377.5; ENST00000465180.5; ENST00000368206.5; ENST00000368209.9
External Link	RMBase: m6A_site_59079
mod ID: M6ASITE061128		Click to Show/Hide the Full List
mod site	chr1:156752202-156752203:-		[6]
Sequence	CACGGCGAGGTCCAGAGAGGACCCCAGTGCGCGGAGCGGCA
Motif Score	3.622404762
Cell/Tissue List	HeLa; Huh7; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000471377.5; ENST00000368209.9; ENST00000368206.5; ENST00000465180.5
External Link	RMBase: m6A_site_59080
mod ID: M6ASITE061129		Click to Show/Hide the Full List
mod site	chr1:156752303-156752304:-		[6]
Sequence	GGCCATCTCCTGGCTACCAAACTCAAGCGTTTCCTCCTTAG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000368206.5; ENST00000465180.5
External Link	RMBase: m6A_site_59081
mod ID: M6ASITE061130		Click to Show/Hide the Full List
mod site	chr1:156752388-156752389:-		[6]
Sequence	GTCCAAGTCTCCTTGGCAAGACAGTAGCTTAGAGAAACGAG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000368206.5; ENST00000465180.5
External Link	RMBase: m6A_site_59082

Ref 1	METTL3-mediated m(6)A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance. Gut. 2020 Jul;69(7):1193-1205. doi: 10.1136/gutjnl-2019-319639. Epub 2019 Oct 3.
Ref 2	FDA Approved Drug Products from FDA Official Website. 2004. Application Number: (ANDA) 125085.
Ref 3	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.
Ref 4	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 5	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 6	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 7	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 8	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 9	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 10	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 11	The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016 May 5;62(3):335-345. doi: 10.1016/j.molcel.2016.03.021. Epub 2016 Apr 21.
Ref 12	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 13	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 14	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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