m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00198)

Target Name	Bax inhibitor 1 (TMBIM6)
Synonyms	BI-1; Testis-enhanced gene transcript protein; Transmembrane BAX inhibitor motif-containing protein 6; BI1; TEGT Click to Show/Hide
Gene Name	TMBIM6
Chromosomal Location	12q13.12
Family	BI1 family
Function	Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity). Click to Show/Hide
Gene ID	7009
Uniprot ID	BI1_HUMAN
HGNC ID	HGNC:11723
KEGG ID	hsa:7009

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

TMBIM6 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) [READER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by IGF2BP3*
Cell Line	ES-2 cell line	Homo sapiens
Treatment: siIGF2BP3 ES-2 cells Control: siControl ES-2 cells		GSE109604
Regulation		logFC: -8.65E-01 p-value: 2.88E-02
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	RBM15-mediated m6A modification of Bax inhibitor 1 (TMBIM6) mRNA enhanced TMBIM6 stability through IGF2BP3-dependent. Laryngeal squamous cell cancer cells were transfected with shRBM15 lentivirus for 48h, and the qRT-PCR data indicated that the mRNA levels of CPNE5, TMBIM6, and ATAD3A decreased after RBM15 knockdown.
Target Regulation	Up regulation
Responsed Disease	Laryngeal cancer		ICD-11: 2C23	Disease Info
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	AMC-HN-8	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_5966
	NHBEC (Normal human bronchial epithelial cell)
	Tu 177	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_4913
	Tu 212	Head and neck squamous cell carcinoma	Homo sapiens	CVCL_4915
In-vivo Model	For tumor growth studies, whether in vivo RBM15 knockdown/overexpression experiments or in vivo rescue experiments, each group included six mice. Each mouse was injected with 100 uL of lentivirus-transfected tumor cells.

RNA-binding motif protein 15 (RBM15) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by RBM15*
Cell Line	Human BJ Fibroblast	Homo sapiens
Treatment: siRBM15 BJ fibroblast Control: siControl BJ fibroblast		GSE154148
Regulation		logFC: -3.57E+00 p-value: 2.49E-07
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	RBM15-mediated m6A modification of Bax inhibitor 1 (TMBIM6) mRNA enhanced TMBIM6 stability through IGF2BP3-dependent. Laryngeal squamous cell cancer cells were transfected with shRBM15 lentivirus for 48h, and the qRT-PCR data indicated that the mRNA levels of CPNE5, TMBIM6, and ATAD3A decreased after RBM15 knockdown.
Target Regulation	Up regulation
Responsed Disease	Laryngeal cancer		ICD-11: 2C23	Disease Info
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	AMC-HN-8	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_5966
	NHBEC (Normal human bronchial epithelial cell)
	Tu 177	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_4913
	Tu 212	Head and neck squamous cell carcinoma	Homo sapiens	CVCL_4915
In-vivo Model	For tumor growth studies, whether in vivo RBM15 knockdown/overexpression experiments or in vivo rescue experiments, each group included six mice. Each mouse was injected with 100 uL of lentivirus-transfected tumor cells.

Laryngeal cancer [ICD-11: 2C23]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	RBM15-mediated m6A modification of Bax inhibitor 1 (TMBIM6) mRNA enhanced TMBIM6 stability through IGF2BP3-dependent. Laryngeal squamous cell cancer cells were transfected with shRBM15 lentivirus for 48h, and the qRT-PCR data indicated that the mRNA levels of CPNE5, TMBIM6, and ATAD3A decreased after RBM15 knockdown.
Responsed Disease	Laryngeal cancer [ICD-11: 2C23]
Target Regulator	Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)		READER	Regulator Info
Target Regulation	Up regulation
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	AMC-HN-8	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_5966
	NHBEC (Normal human bronchial epithelial cell)
	Tu 177	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_4913
	Tu 212	Head and neck squamous cell carcinoma	Homo sapiens	CVCL_4915
In-vivo Model	For tumor growth studies, whether in vivo RBM15 knockdown/overexpression experiments or in vivo rescue experiments, each group included six mice. Each mouse was injected with 100 uL of lentivirus-transfected tumor cells.
Experiment 2 Reporting the m6A-centered Disease Response				[1]
Response Summary	RBM15-mediated m6A modification of Bax inhibitor 1 (TMBIM6) mRNA enhanced TMBIM6 stability through IGF2BP3-dependent. Laryngeal squamous cell cancer cells were transfected with shRBM15 lentivirus for 48h, and the qRT-PCR data indicated that the mRNA levels of CPNE5, TMBIM6, and ATAD3A decreased after RBM15 knockdown.
Responsed Disease	Laryngeal cancer [ICD-11: 2C23]
Target Regulator	RNA-binding motif protein 15 (RBM15)		WRITER	Regulator Info
Target Regulation	Up regulation
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	AMC-HN-8	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_5966
	NHBEC (Normal human bronchial epithelial cell)
	Tu 177	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_4913
	Tu 212	Head and neck squamous cell carcinoma	Homo sapiens	CVCL_4915
In-vivo Model	For tumor growth studies, whether in vivo RBM15 knockdown/overexpression experiments or in vivo rescue experiments, each group included six mice. Each mouse was injected with 100 uL of lentivirus-transfected tumor cells.

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00198)

Bax inhibitor 1 (TMBIM6)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE005526		Click to Show/Hide the Full List
mod site	chr12:49759683-49759684:+		[3]
Sequence	GGGCATGGTGGCACATGTATATAATCCCAGCTACTCAGGAG
Transcript ID List	ENST00000549385.5; ENST00000550040.1; rmsk_3785205; ENST00000549471.1; ENST00000552370.5; ENST00000547798.1; ENST00000267115.10; ENST00000423828.5; ENST00000552699.5; ENST00000547013.1; ENST00000395006.8
External Link	RMBase: RNA-editing_site_28271

N1-methyladenosine (m1A)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M1ASITE000025		Click to Show/Hide the Full List
mod site	chr12:49741556-49741557:+		[4]
Sequence	GGAGCGGAAGTGGGCGAGTCAGAGCACATCCGGTGTTAGAA
Cell/Tissue List	HEK293T
Seq Type List	m1A-MAP-seq
Transcript ID List	ENST00000552635.5; ENST00000551154.5; ENST00000549966.5; ENST00000548894.5; ENST00000548809.5; ENST00000547187.5; ENST00000546914.5; ENST00000552699.5; ENST00000546796.5; ENST00000267115.10; ENST00000547832.5
External Link	RMBase: m1A_site_230

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE005509		Click to Show/Hide the Full List
mod site	chr12:49742269-49742270:+		[5]
Sequence	CGCTCTTTTCGGATTGGTTACCTTTGGGCAGGTGAGGTGGC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000546796.5; ENST00000267115.10; ENST00000546914.5; ENST00000548809.5; ENST00000547187.5; ENST00000550951.5; ENST00000548201.5; ENST00000423828.5; ENST00000548894.5; ENST00000552699.5; ENST00000546885.5; ENST00000549385.5; ENST00000549966.5; ENST00000550445.5; ENST00000551154.5; ENST00000547832.5; ENST00000549445.5; ENST00000548713.5; ENST00000552635.5
External Link	RMBase: m5C_site_9992

N6-methyladenosine (m6A)

In total 88 m6A sequence/site(s) in this target gene
mod ID: M6ASITE012234		Click to Show/Hide the Full List
mod site	chr12:49741621-49741622:+		[6]
Sequence	GGTTAGGAAGGTACGTCTGAACCTAGTACTGGGCGAACTGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hESCs; HEK293T; fibroblasts; H1299; MM6; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000267115.10; ENST00000552635.5; ENST00000549966.5; ENST00000546796.5; ENST00000551154.5; ENST00000547187.5; ENST00000548894.5; ENST00000548713.5; ENST00000549385.5; ENST00000547832.5; ENST00000546914.5; ENST00000552699.5; ENST00000550951.5; ENST00000549445.5; ENST00000546885.5; ENST00000548809.5; ENST00000548201.5
External Link	RMBase: m6A_site_187209
mod ID: M6ASITE012236		Click to Show/Hide the Full List
mod site	chr12:49741637-49741638:+		[6]
Sequence	CTGAACCTAGTACTGGGCGAACTGGGAGTGAGAAATGGAAA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hESCs; HEK293T; fibroblasts; H1299; MM6; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000550951.5; ENST00000547832.5; ENST00000546885.5; ENST00000547187.5; ENST00000548713.5; ENST00000549966.5; ENST00000548201.5; ENST00000546914.5; ENST00000551154.5; ENST00000552699.5; ENST00000548809.5; ENST00000552635.5; ENST00000548894.5; ENST00000549445.5; ENST00000549385.5; ENST00000546796.5; ENST00000267115.10
External Link	RMBase: m6A_site_187210
mod ID: M6ASITE012237		Click to Show/Hide the Full List
mod site	chr12:49741710-49741711:+		[6]
Sequence	GCAGTAGCTTCCTTCTGCGGACAGATGGCACCCTGAAGGAA
Motif Score	3.643047619
Cell/Tissue List	HeLa; Huh7; HEK293A-TOA; TIME; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000547187.5; ENST00000546796.5; ENST00000546885.5; ENST00000548201.5; ENST00000549445.5; ENST00000551154.5; ENST00000549385.5; ENST00000548894.5; ENST00000267115.10; ENST00000548713.5; ENST00000547832.5; ENST00000550951.5; ENST00000549966.5; ENST00000552699.5; ENST00000546914.5; ENST00000548809.5; ENST00000552635.5
External Link	RMBase: m6A_site_187211
mod ID: M6ASITE012238		Click to Show/Hide the Full List
mod site	chr12:49741748-49741749:+		[6]
Sequence	GAACGAGGCCCTGCTCGGAGACCAGACTCGGGAAAACAGGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000547187.5; ENST00000552635.5; ENST00000267115.10; ENST00000547832.5; ENST00000548201.5; ENST00000552699.5; ENST00000551154.5; ENST00000546914.5; ENST00000548894.5; ENST00000549385.5; ENST00000548809.5; ENST00000550951.5; ENST00000549445.5; ENST00000546796.5; ENST00000548713.5; ENST00000549966.5; ENST00000546885.5
External Link	RMBase: m6A_site_187212
mod ID: M6ASITE012239		Click to Show/Hide the Full List
mod site	chr12:49741753-49741754:+		[6]
Sequence	AGGCCCTGCTCGGAGACCAGACTCGGGAAAACAGGGTGTGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000547187.5; ENST00000551154.5; ENST00000267115.10; ENST00000549385.5; ENST00000552635.5; ENST00000549966.5; ENST00000548809.5; ENST00000546796.5; ENST00000548201.5; ENST00000550951.5; ENST00000548713.5; ENST00000546914.5; ENST00000549445.5; ENST00000547832.5; ENST00000546885.5; ENST00000552699.5; ENST00000548894.5
External Link	RMBase: m6A_site_187213
mod ID: M6ASITE012240		Click to Show/Hide the Full List
mod site	chr12:49741763-49741764:+		[6]
Sequence	CGGAGACCAGACTCGGGAAAACAGGGTGTGGAGGGAAGCTA
Motif Score	2.20572619
Cell/Tissue List	HeLa; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000548809.5; ENST00000548894.5; ENST00000552635.5; ENST00000552699.5; ENST00000551154.5; ENST00000550951.5; ENST00000549966.5; ENST00000546796.5; ENST00000547832.5; ENST00000546885.5; ENST00000549445.5; ENST00000548201.5; ENST00000546914.5; ENST00000549385.5; ENST00000267115.10; ENST00000547187.5; ENST00000548713.5
External Link	RMBase: m6A_site_187214
mod ID: M6ASITE012241		Click to Show/Hide the Full List
mod site	chr12:49742028-49742029:+		[7]
Sequence	CCGAGGTGAAGGAACGCGAAACTCCACCCATCCGATTGCTG
Motif Score	2.627720238
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000546914.5; ENST00000546885.5; ENST00000549445.5; ENST00000550951.5; ENST00000548201.5; ENST00000547832.5; ENST00000550445.5; ENST00000547187.5; ENST00000548894.5; ENST00000552635.5; ENST00000551154.5; ENST00000548713.5; ENST00000549385.5; ENST00000548809.5; ENST00000549966.5; ENST00000552699.5; ENST00000546796.5; ENST00000267115.10; ENST00000423828.5
External Link	RMBase: m6A_site_187215
mod ID: M6ASITE012242		Click to Show/Hide the Full List
mod site	chr12:49742108-49742109:+		[7]
Sequence	GTGAGCGGCCCGGAGCCAAGACTCGAGGTAGGGCCTGGCGG
Motif Score	3.319380952
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000548201.5; ENST00000549966.5; ENST00000423828.5; ENST00000549445.5; ENST00000547832.5; ENST00000550951.5; ENST00000552699.5; ENST00000548894.5; ENST00000267115.10; ENST00000546885.5; ENST00000548809.5; ENST00000546796.5; ENST00000548713.5; ENST00000549385.5; ENST00000546914.5; ENST00000552635.5; ENST00000551154.5; ENST00000550445.5; ENST00000547187.5
External Link	RMBase: m6A_site_187216
mod ID: M6ASITE012243		Click to Show/Hide the Full List
mod site	chr12:49749654-49749655:+		[8]
Sequence	GTTGGCCAGACTGGTCTCGAACTCCTGACGTCAAAGTGATC
Motif Score	3.373380952
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000547187.5; ENST00000549130.5; ENST00000549445.5; ENST00000548713.5; ENST00000549385.5; ENST00000547832.5; ENST00000552699.5; ENST00000550951.5; ENST00000551154.5; ENST00000548201.5; ENST00000552635.5; ENST00000267115.10; ENST00000550445.5; ENST00000423828.5; ENST00000546914.5; ENST00000546796.5; ENST00000549966.5; ENST00000548809.5; ENST00000548894.5
External Link	RMBase: m6A_site_187217
mod ID: M6ASITE012244		Click to Show/Hide the Full List
mod site	chr12:49750682-49750683:+		[9]
Sequence	CACTGTATCTGTCCTTAAGAACAGAATTAACAAAAGTTCTG
Motif Score	2.951386905
Cell/Tissue List	A549; HepG2; HeLa; fibroblasts; LCLs; MT4; iSLK; MSC; TIME; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000552699.5; ENST00000547832.5; ENST00000423828.5; ENST00000548713.5; ENST00000267115.10; ENST00000549445.5; ENST00000548201.5; ENST00000546796.5; ENST00000552635.5; ENST00000547187.5; ENST00000550445.5; ENST00000549130.5; ENST00000546914.5; ENST00000550951.5; ENST00000548894.5; ENST00000552370.5; ENST00000551154.5; ENST00000549966.5; ENST00000549385.5; ENST00000548809.5
External Link	RMBase: m6A_site_187218
mod ID: M6ASITE012245		Click to Show/Hide the Full List
mod site	chr12:49752470-49752471:+		[9]
Sequence	CTTTATTCTGCAGAGTGGAGACTGCTGCACGGACTCTGGAA
Motif Score	3.319380952
Cell/Tissue List	A549; HepG2; HeLa; fibroblasts; MT4; iSLK; MSC; TIME; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000550445.5; ENST00000548201.5; ENST00000548713.5; ENST00000547832.5; ENST00000552370.5; ENST00000551154.5; ENST00000395006.8; ENST00000267115.10; ENST00000546796.5; ENST00000548894.5; ENST00000552635.5; ENST00000546914.5; ENST00000423828.5; ENST00000548809.5; ENST00000549966.5; ENST00000547187.5; ENST00000549385.5; ENST00000552699.5; ENST00000549445.5; ENST00000550951.5; ENST00000549130.5
External Link	RMBase: m6A_site_187219
mod ID: M6ASITE012247		Click to Show/Hide the Full List
mod site	chr12:49752482-49752483:+		[9]
Sequence	GAGTGGAGACTGCTGCACGGACTCTGGAACCATGAACATAT
Motif Score	4.065041667
Cell/Tissue List	A549; HepG2; HeLa; fibroblasts; MT4; iSLK; MSC; TIME; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000549966.5; ENST00000549385.5; ENST00000267115.10; ENST00000552370.5; ENST00000549130.5; ENST00000550445.5; ENST00000552699.5; ENST00000548713.5; ENST00000548894.5; ENST00000546914.5; ENST00000546796.5; ENST00000550951.5; ENST00000551154.5; ENST00000547832.5; ENST00000548201.5; ENST00000547187.5; ENST00000423828.5; ENST00000395006.8; ENST00000548809.5; ENST00000549445.5; ENST00000552635.5
External Link	RMBase: m6A_site_187220
mod ID: M6ASITE012248		Click to Show/Hide the Full List
mod site	chr12:49752490-49752491:+		[9]
Sequence	ACTGCTGCACGGACTCTGGAACCATGAACATATTTGATCGA
Motif Score	2.930744048
Cell/Tissue List	A549; HepG2; HeLa; fibroblasts; MT4; iSLK; MSC; TIME; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000550951.5; ENST00000395006.8; ENST00000548201.5; ENST00000550445.5; ENST00000549385.5; ENST00000267115.10; ENST00000546796.5; ENST00000552370.5; ENST00000548894.5; ENST00000548809.5; ENST00000552635.5; ENST00000551154.5; ENST00000547187.5; ENST00000547832.5; ENST00000548713.5; ENST00000552699.5; ENST00000549130.5; ENST00000546914.5; ENST00000549966.5; ENST00000549445.5; ENST00000423828.5
External Link	RMBase: m6A_site_187221
mod ID: M6ASITE012249		Click to Show/Hide the Full List
mod site	chr12:49752497-49752498:+		[9]
Sequence	CACGGACTCTGGAACCATGAACATATTTGATCGAAAGATCA
Motif Score	2.951386905
Cell/Tissue List	A549; hESC-HEK293T; HepG2; HeLa; fibroblasts; MT4; iSLK; MSC; TIME; TREX
Seq Type List	MeRIP-seq; MAZTER-seq; m6A-seq
Transcript ID List	ENST00000548201.5; ENST00000552370.5; ENST00000546796.5; ENST00000549966.5; ENST00000549445.5; ENST00000550951.5; ENST00000395006.8; ENST00000549385.5; ENST00000548894.5; ENST00000548809.5; ENST00000423828.5; ENST00000267115.10; ENST00000548713.5; ENST00000551154.5; ENST00000550445.5; ENST00000547187.5; ENST00000546914.5; ENST00000547832.5; ENST00000552635.5; ENST00000552699.5; ENST00000549130.5
External Link	RMBase: m6A_site_187222
mod ID: M6ASITE012250		Click to Show/Hide the Full List
mod site	chr12:49752973-49752974:+		[9]
Sequence	ATTCACATTCTTTTCTTAGAACCCCGTCAACGCAGCAGCAC
Motif Score	2.930744048
Cell/Tissue List	A549; HepG2; MT4; iSLK; MSC; TIME; TREX
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000423828.5; ENST00000552699.5; ENST00000549966.5; ENST00000548201.5; ENST00000551154.5; ENST00000267115.10; ENST00000546796.5; ENST00000547798.1; ENST00000549445.5; ENST00000552370.5; ENST00000546914.5; ENST00000547832.5; ENST00000549130.5; ENST00000550445.5; ENST00000550951.5; ENST00000552635.5; ENST00000549385.5; ENST00000395006.8; ENST00000547187.5
External Link	RMBase: m6A_site_187223
mod ID: M6ASITE012251		Click to Show/Hide the Full List
mod site	chr12:49752982-49752983:+		[10]
Sequence	CTTTTCTTAGAACCCCGTCAACGCAGCAGCACCTGAAGAAG
Motif Score	2.147845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000547187.5; ENST00000546796.5; ENST00000552370.5; ENST00000547798.1; ENST00000549130.5; ENST00000551154.5; ENST00000547832.5; ENST00000548201.5; ENST00000423828.5; ENST00000552635.5; ENST00000550951.5; ENST00000267115.10; ENST00000550445.5; ENST00000549966.5; ENST00000546914.5; ENST00000549385.5; ENST00000552699.5; ENST00000549445.5; ENST00000395006.8
External Link	RMBase: m6A_site_187224
mod ID: M6ASITE012252		Click to Show/Hide the Full List
mod site	chr12:49755688-49755689:+		[11]
Sequence	TGATGATTTGGCTGATGGCAACACCTCATAGCCATGAAACT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552699.5; ENST00000552635.5; ENST00000547832.5; ENST00000549385.5; ENST00000423828.5; ENST00000546914.5; ENST00000547187.5; ENST00000395006.8; ENST00000548201.5; ENST00000546796.5; ENST00000267115.10; ENST00000549966.5; ENST00000549445.5; ENST00000547798.1; ENST00000550445.5; ENST00000549130.5; ENST00000553022.1; ENST00000552370.5
External Link	RMBase: m6A_site_187225
mod ID: M6ASITE012253		Click to Show/Hide the Full List
mod site	chr12:49755711-49755712:+		[10]
Sequence	CCTCATAGCCATGAAACTGAACAGAAAAGACTGGGACTTCT
Motif Score	2.951386905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552699.5; ENST00000549966.5; ENST00000267115.10; ENST00000423828.5; ENST00000552370.5; ENST00000547187.5; ENST00000395006.8; ENST00000550445.5; ENST00000548201.5; ENST00000546796.5; ENST00000549445.5; ENST00000549385.5; ENST00000546914.5; ENST00000553022.1; ENST00000547798.1; ENST00000552635.5; ENST00000547832.5; ENST00000549130.5
External Link	RMBase: m6A_site_187226
mod ID: M6ASITE012254		Click to Show/Hide the Full List
mod site	chr12:49755751-49755752:+		[12]
Sequence	TTGCTGGATTTGCATTCCTTACAGGTACGTTAAGGGATTTG
Motif Score	2.07285119
Cell/Tissue List	liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000552370.5; ENST00000552699.5; ENST00000546796.5; ENST00000552635.5; ENST00000549385.5; ENST00000547187.5; ENST00000547832.5; ENST00000553022.1; ENST00000547798.1; ENST00000548201.5; ENST00000550445.5; ENST00000267115.10; ENST00000423828.5; ENST00000549966.5; ENST00000549445.5; ENST00000395006.8; ENST00000546914.5
External Link	RMBase: m6A_site_187227
mod ID: M6ASITE012255		Click to Show/Hide the Full List
mod site	chr12:49759224-49759225:+		[6]
Sequence	CTCTTACATTTGTTAGGCAAACCTGTATGTGGGACTGGTGG
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000552370.5; ENST00000423828.5; ENST00000552699.5; ENST00000267115.10; ENST00000395006.8; ENST00000549385.5; ENST00000547798.1; ENST00000550040.1; ENST00000549471.1; ENST00000547013.1
External Link	RMBase: m6A_site_187228
mod ID: M6ASITE012256		Click to Show/Hide the Full List
mod site	chr12:49759237-49759238:+		[6]
Sequence	TAGGCAAACCTGTATGTGGGACTGGTGGTCATGTGTGGCTT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000549385.5; ENST00000547798.1; ENST00000549471.1; ENST00000547013.1; ENST00000550040.1; ENST00000552370.5; ENST00000267115.10; ENST00000395006.8; ENST00000423828.5; ENST00000552699.5
External Link	RMBase: m6A_site_187229
mod ID: M6ASITE012258		Click to Show/Hide the Full List
mod site	chr12:49759271-49759272:+		[10]
Sequence	GTGGCTTCGTCCTTTTTGATACTCAACTCATTATTGAAAAG
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552699.5; ENST00000395006.8; ENST00000547798.1; ENST00000423828.5; ENST00000550040.1; ENST00000549471.1; ENST00000549385.5; ENST00000552370.5; ENST00000267115.10; ENST00000547013.1
External Link	RMBase: m6A_site_187230
mod ID: M6ASITE012259		Click to Show/Hide the Full List
mod site	chr12:49759276-49759277:+		[10]
Sequence	TTCGTCCTTTTTGATACTCAACTCATTATTGAAAAGGCCGA
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000552699.5; ENST00000552370.5; ENST00000549471.1; ENST00000395006.8; ENST00000549385.5; ENST00000550040.1; ENST00000423828.5; ENST00000547798.1; ENST00000547013.1
External Link	RMBase: m6A_site_187231
mod ID: M6ASITE012260		Click to Show/Hide the Full List
mod site	chr12:49759297-49759298:+		[6]
Sequence	CTCATTATTGAAAAGGCCGAACATGGAGATCAAGATTATAT
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000549471.1; ENST00000552370.5; ENST00000547013.1; ENST00000550040.1; ENST00000552699.5; ENST00000423828.5; ENST00000549385.5; ENST00000267115.10; ENST00000395006.8; ENST00000547798.1
External Link	RMBase: m6A_site_187232
mod ID: M6ASITE012261		Click to Show/Hide the Full List
mod site	chr12:49761734-49761735:+		[10]
Sequence	ATCTCTTCTTAGATTTCATTACTGTCTTCAGAAAACTCATG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000549471.1; ENST00000547798.1; ENST00000552699.5; ENST00000552370.5; ENST00000547013.1; ENST00000267115.10; ENST00000550040.1; ENST00000423828.5; ENST00000395006.8; ENST00000549385.5
External Link	RMBase: m6A_site_187233
mod ID: M6ASITE012262		Click to Show/Hide the Full List
mod site	chr12:49761748-49761749:+		[6]
Sequence	TTCATTACTGTCTTCAGAAAACTCATGATGATCCTGGCCAT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000552699.5; ENST00000395006.8; ENST00000547798.1; ENST00000547013.1; ENST00000549385.5; ENST00000267115.10; ENST00000423828.5; ENST00000549471.1; ENST00000550040.1; ENST00000552370.5
External Link	RMBase: m6A_site_187234
mod ID: M6ASITE012263		Click to Show/Hide the Full List
mod site	chr12:49761807-49761808:+		[6]
Sequence	GCCTACAACCCAAAGATGAGACAATAATGGCTCCTGAGCTT
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000549385.5; ENST00000552370.5; ENST00000549471.1; ENST00000552699.5; ENST00000395006.8; ENST00000550040.1; ENST00000267115.10; ENST00000547798.1; ENST00000423828.5
External Link	RMBase: m6A_site_187235
mod ID: M6ASITE012264		Click to Show/Hide the Full List
mod site	chr12:49761856-49761857:+		[6]
Sequence	TGTATACTTCAGATTTGAAAACTTGCTCACACACTGTGTTA
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000549385.5; ENST00000552699.5; ENST00000552370.5; ENST00000549471.1; ENST00000395006.8; ENST00000267115.10; ENST00000550040.1; ENST00000423828.5; ENST00000547798.1
External Link	RMBase: m6A_site_187236
mod ID: M6ASITE012265		Click to Show/Hide the Full List
mod site	chr12:49762114-49762115:+		[6]
Sequence	GTTGTAAATTTCAGAAGTAGACTAATTTTATCCATTTGTTA
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000267115.10; ENST00000547798.1; ENST00000549385.5; ENST00000549471.1; ENST00000395006.8; ENST00000552699.5; ENST00000552370.5; ENST00000550040.1; ENST00000423828.5
External Link	RMBase: m6A_site_187237
mod ID: M6ASITE012266		Click to Show/Hide the Full List
mod site	chr12:49762900-49762901:+		[10]
Sequence	GAAAGAGAAGAAATGAAGTGACCATCCAGCCTTTCCCAATT
Motif Score	2.839113095
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000549471.1; ENST00000549385.5; ENST00000552699.5; ENST00000267115.10; ENST00000395006.8; ENST00000552370.5; ENST00000547798.1; ENST00000423828.5
External Link	RMBase: m6A_site_187238
mod ID: M6ASITE012267		Click to Show/Hide the Full List
mod site	chr12:49762923-49762924:+		[6]
Sequence	ATCCAGCCTTTCCCAATTAGACTTCCTCTCCTTCCACCCCT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; AML
Seq Type List	m6A-seq; DART-seq; miCLIP
Transcript ID List	ENST00000267115.10; ENST00000549385.5; ENST00000552699.5; ENST00000552370.5; ENST00000395006.8; ENST00000423828.5; ENST00000547798.1; ENST00000549471.1
External Link	RMBase: m6A_site_187239
mod ID: M6ASITE012269		Click to Show/Hide the Full List
mod site	chr12:49762958-49762959:+		[11]
Sequence	ACCCCTCATTTCCTTTTTGCACACATTACAGGTGGTGTGTT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000549385.5; ENST00000549471.1; ENST00000552699.5; ENST00000395006.8; ENST00000267115.10; ENST00000547798.1; ENST00000423828.5
External Link	RMBase: m6A_site_187240
mod ID: M6ASITE012270		Click to Show/Hide the Full List
mod site	chr12:49762965-49762966:+		[10]
Sequence	ATTTCCTTTTTGCACACATTACAGGTGGTGTGTTCTGTGAT
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000395006.8; ENST00000552699.5; ENST00000423828.5; ENST00000549385.5; ENST00000549471.1; ENST00000547798.1; ENST00000267115.10
External Link	RMBase: m6A_site_187241
mod ID: M6ASITE012271		Click to Show/Hide the Full List
mod site	chr12:49763013-49763014:+		[10]
Sequence	AGCATCAGAAAAGCTTTTGTACTTTGTGGTTTCCTCTATTT
Motif Score	3.278136905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000549471.1; ENST00000423828.5; ENST00000549385.5; ENST00000267115.10; ENST00000395006.8; ENST00000552699.5; ENST00000547798.1
External Link	RMBase: m6A_site_187242
mod ID: M6ASITE012272		Click to Show/Hide the Full List
mod site	chr12:49763053-49763054:+		[6]
Sequence	TTGAATTTTTTGATCAAAAAACTGATTAGCAGAATATAGTT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000395006.8; ENST00000423828.5; ENST00000547798.1; ENST00000549471.1; ENST00000267115.10; ENST00000552699.5; ENST00000549385.5
External Link	RMBase: m6A_site_187243
mod ID: M6ASITE012273		Click to Show/Hide the Full List
mod site	chr12:49763148-49763149:+		[10]
Sequence	CATCTGTAGCCTCTTCCTCTACTCAGGCAGTCGACCCGCCA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000549385.5; ENST00000395006.8; ENST00000547798.1; ENST00000552699.5; ENST00000267115.10; ENST00000423828.5
External Link	RMBase: m6A_site_187244
mod ID: M6ASITE012274		Click to Show/Hide the Full List
mod site	chr12:49763161-49763162:+		[10]
Sequence	TTCCTCTACTCAGGCAGTCGACCCGCCACGATGAGAAGTGG
Motif Score	2.844928571
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000267115.10; ENST00000395006.8; ENST00000547798.1; ENST00000552699.5; ENST00000549385.5
External Link	RMBase: m6A_site_187245
mod ID: M6ASITE012275		Click to Show/Hide the Full List
mod site	chr12:49763183-49763184:+		[13]
Sequence	CCGCCACGATGAGAAGTGGGACCAGCAGAGGGCGCCAACTT
Motif Score	3.622404762
Cell/Tissue List	HepG2; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000423828.5; ENST00000547798.1; ENST00000395006.8; ENST00000267115.10; ENST00000549385.5; ENST00000552699.5
External Link	RMBase: m6A_site_187246
mod ID: M6ASITE012276		Click to Show/Hide the Full List
mod site	chr12:49763244-49763245:+		[13]
Sequence	AGGCTTCATTCACCCAGTGGACCTGAACTGTTTGGTAGAGC
Motif Score	3.622404762
Cell/Tissue List	HepG2; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552699.5; ENST00000395006.8; ENST00000549385.5; ENST00000423828.5; ENST00000267115.10; ENST00000547798.1
External Link	RMBase: m6A_site_187247
mod ID: M6ASITE012277		Click to Show/Hide the Full List
mod site	chr12:49763250-49763251:+		[13]
Sequence	CATTCACCCAGTGGACCTGAACTGTTTGGTAGAGCCACCCG
Motif Score	3.373380952
Cell/Tissue List	HepG2; MSC; endometrial; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000395006.8; ENST00000267115.10; ENST00000547798.1; ENST00000423828.5; ENST00000549385.5; ENST00000552699.5
External Link	RMBase: m6A_site_187248
mod ID: M6ASITE012278		Click to Show/Hide the Full List
mod site	chr12:49763318-49763319:+		[13]
Sequence	ATGCGCACAGTTCCTGTGGGACTGGGCCGTGAGTTTTCCAT
Motif Score	4.065041667
Cell/Tissue List	HepG2; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000423828.5; ENST00000547798.1; ENST00000549385.5; ENST00000395006.8; ENST00000552699.5; ENST00000267115.10
External Link	RMBase: m6A_site_187249
mod ID: M6ASITE012280		Click to Show/Hide the Full List
mod site	chr12:49763368-49763369:+		[10]
Sequence	GTTCAGTGGTCCCATTGTTAACTCAGCCTCAAATCTCAACT
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552699.5; ENST00000547798.1; ENST00000267115.10; ENST00000395006.8; ENST00000423828.5; ENST00000549385.5
External Link	RMBase: m6A_site_187250
mod ID: M6ASITE012281		Click to Show/Hide the Full List
mod site	chr12:49763386-49763387:+		[10]
Sequence	TAACTCAGCCTCAAATCTCAACTGTCAGGCCCTACAAAGAA
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000549385.5; ENST00000267115.10; ENST00000423828.5; ENST00000547798.1; ENST00000552699.5; ENST00000395006.8
External Link	RMBase: m6A_site_187251
mod ID: M6ASITE012282		Click to Show/Hide the Full List
mod site	chr12:49763399-49763400:+		[11]
Sequence	AATCTCAACTGTCAGGCCCTACAAAGAAAATGGAGAGCCTC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000267115.10; ENST00000423828.5; ENST00000547798.1; ENST00000552699.5; ENST00000549385.5; ENST00000395006.8
External Link	RMBase: m6A_site_187252
mod ID: M6ASITE012283		Click to Show/Hide the Full List
mod site	chr12:49763469-49763470:+		[11]
Sequence	TGCCCATGCTGGTCTGGCAAACACACCTTTCTGCTTTGCCT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000267115.10; ENST00000552699.5; ENST00000547798.1; ENST00000549385.5; ENST00000395006.8; ENST00000423828.5
External Link	RMBase: m6A_site_187253
mod ID: M6ASITE012284		Click to Show/Hide the Full List
mod site	chr12:49763492-49763493:+		[11]
Sequence	CACCTTTCTGCTTTGCCTTCACAAAAGTAATGTGTTCCCTT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552699.5; ENST00000547798.1; ENST00000549385.5; ENST00000423828.5; ENST00000395006.8; ENST00000267115.10
External Link	RMBase: m6A_site_187254
mod ID: M6ASITE012285		Click to Show/Hide the Full List
mod site	chr12:49763578-49763579:+		[11]
Sequence	ATGGGTGGGAAGACTTCAGCACAAAGGAAAGACTAATTCTT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000423828.5; ENST00000395006.8; ENST00000552699.5; ENST00000267115.10; ENST00000549385.5; ENST00000547798.1
External Link	RMBase: m6A_site_187255
mod ID: M6ASITE012286		Click to Show/Hide the Full List
mod site	chr12:49763589-49763590:+		[10]
Sequence	GACTTCAGCACAAAGGAAAGACTAATTCTTGTCAGGCATTT
Motif Score	3.319380952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000395006.8; ENST00000549385.5; ENST00000267115.10; ENST00000423828.5; ENST00000552699.5; ENST00000547798.1
External Link	RMBase: m6A_site_187256
mod ID: M6ASITE012287		Click to Show/Hide the Full List
mod site	chr12:49763639-49763640:+		[10]
Sequence	CTGATTATGTGTATCAAGGTACAGCATCGTAGGGTTCCCCT
Motif Score	2.856142857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000549385.5; ENST00000547798.1; ENST00000267115.10; ENST00000552699.5; ENST00000395006.8
External Link	RMBase: m6A_site_187257
mod ID: M6ASITE012288		Click to Show/Hide the Full List
mod site	chr12:49763662-49763663:+		[10]
Sequence	GCATCGTAGGGTTCCCCTAAACTTGCCCTGTTTTTGTTTTT
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000549385.5; ENST00000552699.5; ENST00000395006.8; ENST00000423828.5; ENST00000547798.1; ENST00000267115.10
External Link	RMBase: m6A_site_187258
mod ID: M6ASITE012289		Click to Show/Hide the Full List
mod site	chr12:49763701-49763702:+		[10]
Sequence	TTTTAGTTTGTTATCCCCTTACTGAGCGGCCTCTACTAGGT
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000395006.8; ENST00000547798.1; ENST00000267115.10; ENST00000552699.5; ENST00000549385.5
External Link	RMBase: m6A_site_187259
mod ID: M6ASITE012291		Click to Show/Hide the Full List
mod site	chr12:49763715-49763716:+		[10]
Sequence	CCCCTTACTGAGCGGCCTCTACTAGGTGGCTGTGATTAAAT
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000395006.8; ENST00000549385.5; ENST00000547798.1; ENST00000267115.10; ENST00000423828.5; ENST00000552699.5
External Link	RMBase: m6A_site_187260
mod ID: M6ASITE012292		Click to Show/Hide the Full List
mod site	chr12:49763803-49763804:+		[14]
Sequence	ATTGTAACCAATCCTGCCAGACCTGTTTGGGGCAGTGGGGA
Motif Score	2.876744048
Cell/Tissue List	MT4; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000547798.1; ENST00000552699.5; ENST00000395006.8; ENST00000267115.10; ENST00000549385.5; ENST00000423828.5
External Link	RMBase: m6A_site_187261
mod ID: M6ASITE012293		Click to Show/Hide the Full List
mod site	chr12:49763828-49763829:+		[14]
Sequence	TTTGGGGCAGTGGGGAGCAAACCTAGATAAGGACCTGTTTG
Motif Score	2.185083333
Cell/Tissue List	MT4; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000395006.8; ENST00000267115.10; ENST00000423828.5; ENST00000549385.5; ENST00000547798.1; ENST00000552699.5
External Link	RMBase: m6A_site_187262
mod ID: M6ASITE012294		Click to Show/Hide the Full List
mod site	chr12:49763840-49763841:+		[14]
Sequence	GGGAGCAAACCTAGATAAGGACCTGTTTGGGGCAGCAGGGA
Motif Score	3.622404762
Cell/Tissue List	MT4; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000549385.5; ENST00000395006.8; ENST00000547798.1; ENST00000267115.10; ENST00000552699.5; ENST00000423828.5
External Link	RMBase: m6A_site_187263
mod ID: M6ASITE012295		Click to Show/Hide the Full List
mod site	chr12:49763876-49763877:+		[11]
Sequence	AGGGAGCAAAATCTCCTTTAACAACCAAGCAGTTCCTCATT
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000267115.10; ENST00000547798.1; ENST00000552699.5; ENST00000395006.8; ENST00000549385.5; ENST00000423828.5
External Link	RMBase: m6A_site_187264
mod ID: M6ASITE012296		Click to Show/Hide the Full List
mod site	chr12:49763898-49763899:+		[10]
Sequence	AACCAAGCAGTTCCTCATTCACATCAACAGAGCGAGGCTGT
Motif Score	2.047297619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000395006.8; ENST00000547798.1; ENST00000549385.5; ENST00000552699.5; ENST00000423828.5
External Link	RMBase: m6A_site_187265
mod ID: M6ASITE012297		Click to Show/Hide the Full List
mod site	chr12:49763904-49763905:+		[10]
Sequence	GCAGTTCCTCATTCACATCAACAGAGCGAGGCTGTGATAAC
Motif Score	2.173910714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000547798.1; ENST00000395006.8; ENST00000549385.5; ENST00000267115.10; ENST00000552699.5; ENST00000423828.5
External Link	RMBase: m6A_site_187266
mod ID: M6ASITE012298		Click to Show/Hide the Full List
mod site	chr12:49763923-49763924:+		[10]
Sequence	AACAGAGCGAGGCTGTGATAACTTAGGAGGCAGCAATCCTA
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000547798.1; ENST00000552699.5; ENST00000267115.10; ENST00000395006.8; ENST00000423828.5; ENST00000549385.5
External Link	RMBase: m6A_site_187267
mod ID: M6ASITE012299		Click to Show/Hide the Full List
mod site	chr12:49763981-49763982:+		[10]
Sequence	TTTAGTCTGTCTCCAACTGGACACCAGTAGGTAGTGTCAAG
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T; MT4
Seq Type List	DART-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000423828.5; ENST00000549385.5; ENST00000552699.5; ENST00000267115.10; ENST00000547798.1; ENST00000395006.8
External Link	RMBase: m6A_site_187268
mod ID: M6ASITE012300		Click to Show/Hide the Full List
mod site	chr12:49764037-49764038:+		[10]
Sequence	AGTAGATAAATGTTCATTTTACTGATGCACTTTAGTTTTTG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000549385.5; ENST00000267115.10; ENST00000547798.1; ENST00000552699.5; ENST00000395006.8
External Link	RMBase: m6A_site_187269
mod ID: M6ASITE012302		Click to Show/Hide the Full List
mod site	chr12:49764045-49764046:+		[10]
Sequence	AATGTTCATTTTACTGATGCACTTTAGTTTTTGGTCTGTTA
Motif Score	3.252583333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000395006.8; ENST00000267115.10; ENST00000423828.5; ENST00000547798.1; ENST00000552699.5; ENST00000549385.5
External Link	RMBase: m6A_site_187270
mod ID: M6ASITE012303		Click to Show/Hide the Full List
mod site	chr12:49764110-49764111:+		[10]
Sequence	TTTTAGGCGGGAGTTAGGCGACCAAACCAGTGAGAGCCCCA
Motif Score	2.844928571
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000547798.1; ENST00000267115.10; ENST00000549385.5; ENST00000423828.5; ENST00000552699.5; ENST00000395006.8
External Link	RMBase: m6A_site_187271
mod ID: M6ASITE012304		Click to Show/Hide the Full List
mod site	chr12:49764165-49764166:+		[12]
Sequence	GTGGCTTCAAGTGTGGGTGGACAGTCCTAATGGGGATCTCC
Motif Score	3.643047619
Cell/Tissue List	brain; HEK293T
Seq Type List	m6A-REF-seq; DART-seq
Transcript ID List	ENST00000267115.10; ENST00000549385.5; ENST00000423828.5; ENST00000547798.1; ENST00000395006.8; ENST00000552699.5
External Link	RMBase: m6A_site_187272
mod ID: M6ASITE012305		Click to Show/Hide the Full List
mod site	chr12:49764211-49764212:+		[10]
Sequence	CTTCCTGTGGGCTGCCACAGACAGCTACCCCCAGAAGGGTC
Motif Score	2.897386905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000547798.1; ENST00000552699.5; ENST00000549385.5; ENST00000423828.5; ENST00000395006.8
External Link	RMBase: m6A_site_187273
mod ID: M6ASITE012306		Click to Show/Hide the Full List
mod site	chr12:49764266-49764267:+		[12]
Sequence	TTGTGGCTCTGAGCTGCTCTACAGAGCTTCAGTGTGAGAGG
Motif Score	2.078666667
Cell/Tissue List	HEK293; HEK293T
Seq Type List	m6A-REF-seq; DART-seq
Transcript ID List	ENST00000552699.5; ENST00000549385.5; ENST00000267115.10; ENST00000395006.8; ENST00000423828.5; ENST00000547798.1
External Link	RMBase: m6A_site_187274
mod ID: M6ASITE012307		Click to Show/Hide the Full List
mod site	chr12:49764309-49764310:+		[10]
Sequence	CGAGCCATTGAAAGCTCATTACCAGTAGGACATAATTTTTG
Motif Score	2.052208333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552699.5; ENST00000549385.5; ENST00000547798.1; ENST00000423828.5; ENST00000395006.8; ENST00000267115.10
External Link	RMBase: m6A_site_187275
mod ID: M6ASITE012308		Click to Show/Hide the Full List
mod site	chr12:49764318-49764319:+		[10]
Sequence	GAAAGCTCATTACCAGTAGGACATAATTTTTGGCTCTCCCT
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000552699.5; ENST00000395006.8; ENST00000267115.10; ENST00000423828.5; ENST00000547798.1; ENST00000549385.5
External Link	RMBase: m6A_site_187276
mod ID: M6ASITE012309		Click to Show/Hide the Full List
mod site	chr12:49764343-49764344:+		[10]
Sequence	ATTTTTGGCTCTCCCTATTCACAACCAGTGCACAGTTTGAC
Motif Score	2.047297619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000552699.5; ENST00000549385.5; ENST00000395006.8; ENST00000547798.1; ENST00000267115.10
External Link	RMBase: m6A_site_187277
mod ID: M6ASITE012310		Click to Show/Hide the Full List
mod site	chr12:49764362-49764363:+		[10]
Sequence	CACAACCAGTGCACAGTTTGACACAGTGGCCTCAGGTTCAC
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000547798.1; ENST00000549385.5; ENST00000395006.8; ENST00000552699.5; ENST00000423828.5
External Link	RMBase: m6A_site_187278
mod ID: M6ASITE012311		Click to Show/Hide the Full List
mod site	chr12:49764409-49764410:+		[10]
Sequence	CCATGTCACTGTGCTATCCTACGAAATCATTTGTTTCTAAG
Motif Score	2.05260119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000552699.5; ENST00000547798.1; ENST00000549385.5; ENST00000423828.5; ENST00000395006.8
External Link	RMBase: m6A_site_187279
mod ID: M6ASITE012313		Click to Show/Hide the Full List
mod site	chr12:49764450-49764451:+		[10]
Sequence	TTGTGTTTATTCCTGGAGTGACATGCCACCCCGAATGGCTC
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000395006.8; ENST00000552699.5; ENST00000547798.1; ENST00000423828.5; ENST00000549385.5; ENST00000267115.10
External Link	RMBase: m6A_site_187280
mod ID: M6ASITE012314		Click to Show/Hide the Full List
mod site	chr12:49764471-49764472:+		[10]
Sequence	CATGCCACCCCGAATGGCTCACTTTCACTGAGGATGCTGTC
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000395006.8; ENST00000552699.5; ENST00000547798.1; ENST00000549385.5; ENST00000423828.5; ENST00000267115.10
External Link	RMBase: m6A_site_187281
mod ID: M6ASITE012315		Click to Show/Hide the Full List
mod site	chr12:49764530-49764531:+		[6]
Sequence	CTCCAGCCTCTGGCTTGAGAACTTACTAAAGGCACTTCCTT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000549385.5; ENST00000547798.1; ENST00000267115.10; ENST00000395006.8; ENST00000423828.5; ENST00000552699.5
External Link	RMBase: m6A_site_187282
mod ID: M6ASITE012316		Click to Show/Hide the Full List
mod site	chr12:49764534-49764535:+		[10]
Sequence	AGCCTCTGGCTTGAGAACTTACTAAAGGCACTTCCTTCCTG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000395006.8; ENST00000547798.1; ENST00000552699.5; ENST00000267115.10; ENST00000423828.5; ENST00000549385.5
External Link	RMBase: m6A_site_187283
mod ID: M6ASITE012317		Click to Show/Hide the Full List
mod site	chr12:49764559-49764560:+		[6]
Sequence	AGGCACTTCCTTCCTGTTAAACCCCTGTTAACTCTCCATAA
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000267115.10; ENST00000423828.5; ENST00000395006.8; ENST00000549385.5; ENST00000552699.5; ENST00000547798.1
External Link	RMBase: m6A_site_187284
mod ID: M6ASITE012318		Click to Show/Hide the Full List
mod site	chr12:49764618-49764619:+		[11]
Sequence	AGGCCTAAGATTTTGAGTTAACATCTCTTGAAGCCAAACTC
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000549385.5; ENST00000267115.10; ENST00000552699.5; ENST00000423828.5; ENST00000395006.8; ENST00000547798.1
External Link	RMBase: m6A_site_187285
mod ID: M6ASITE012319		Click to Show/Hide the Full List
mod site	chr12:49764635-49764636:+		[6]
Sequence	TTAACATCTCTTGAAGCCAAACTCCACCTTCTGTGCTTTTT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000549385.5; ENST00000395006.8; ENST00000423828.5; ENST00000547798.1; ENST00000552699.5; ENST00000267115.10
External Link	RMBase: m6A_site_187286
mod ID: M6ASITE012320		Click to Show/Hide the Full List
mod site	chr12:49764685-49764686:+		[6]
Sequence	AATGGAGTTTTTCTTTAGAAACAGTGCCAAGAATGACAAGA
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000423828.5; ENST00000267115.10; ENST00000547798.1; ENST00000395006.8; ENST00000552699.5; ENST00000549385.5
External Link	RMBase: m6A_site_187287
mod ID: M6ASITE012321		Click to Show/Hide the Full List
mod site	chr12:49764700-49764701:+		[10]
Sequence	TAGAAACAGTGCCAAGAATGACAAGATATTAAAAAAAAAAA
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552699.5; ENST00000423828.5; rmsk_3785211; ENST00000395006.8; ENST00000547798.1; ENST00000549385.5; ENST00000267115.10
External Link	RMBase: m6A_site_187288
mod ID: M6ASITE012322		Click to Show/Hide the Full List
mod site	chr12:49764739-49764740:+		[6]
Sequence	AAAGAAAGAAAAAAAAAAAAACACCTACTTTTAAAGAAAAT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000267115.10; ENST00000395006.8; rmsk_3785211; ENST00000423828.5
External Link	RMBase: m6A_site_187289
mod ID: M6ASITE012324		Click to Show/Hide the Full List
mod site	chr12:49764745-49764746:+		[10]
Sequence	AGAAAAAAAAAAAAACACCTACTTTTAAAGAAAATACCTAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000423828.5
External Link	RMBase: m6A_site_187290
mod ID: M6ASITE012325		Click to Show/Hide the Full List
mod site	chr12:49764760-49764761:+		[10]
Sequence	CACCTACTTTTAAAGAAAATACCTAACAGATTTTTAATATA
Motif Score	2.089839286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000423828.5
External Link	RMBase: m6A_site_187291
mod ID: M6ASITE012326		Click to Show/Hide the Full List
mod site	chr12:49764765-49764766:+		[10]
Sequence	ACTTTTAAAGAAAATACCTAACAGATTTTTAATATAGTTAT
Motif Score	2.168095238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000267115.10
External Link	RMBase: m6A_site_187292
mod ID: M6ASITE012327		Click to Show/Hide the Full List
mod site	chr12:49764790-49764791:+		[10]
Sequence	TTTTTAATATAGTTATCTCTACCACTTTCTTTTCTAGTTTC
Motif Score	2.05802381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000267115.10
External Link	RMBase: m6A_site_187293
mod ID: M6ASITE012328		Click to Show/Hide the Full List
mod site	chr12:49764838-49764839:+		[10]
Sequence	TCAGCTCAGGCTGCATTCTAACTCATACTGTGAAGACAAAG
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000267115.10; ENST00000423828.5
External Link	RMBase: m6A_site_187294
mod ID: M6ASITE012329		Click to Show/Hide the Full List
mod site	chr12:49764844-49764845:+		[10]
Sequence	CAGGCTGCATTCTAACTCATACTGTGAAGACAAAGGTGTTT
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000423828.5; ENST00000267115.10
External Link	RMBase: m6A_site_187295
mod ID: M6ASITE012330		Click to Show/Hide the Full List
mod site	chr12:49764853-49764854:+		[10]
Sequence	TTCTAACTCATACTGTGAAGACAAAGGTGTTTTTGATTCAG
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000423828.5; ENST00000267115.10
External Link	RMBase: m6A_site_187296

2'-O-Methylation (2'-O-Me)

In total 2 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000045		Click to Show/Hide the Full List
mod site	chr12:49764265-49764266:+		[15]
Sequence	GTTGTGGCTCTGAGCTGCTCTACAGAGCTTCAGTGTGAGAG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000547798.1; ENST00000267115.10; ENST00000552699.5; ENST00000549385.5; ENST00000395006.8; ENST00000423828.5
External Link	RMBase: Nm_site_1328
mod ID: 2OMSITE000046		Click to Show/Hide the Full List
mod site	chr12:49764533-49764534:+		[15]
Sequence	CAGCCTCTGGCTTGAGAACTTACTAAAGGCACTTCCTTCCT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000552699.5; ENST00000395006.8; ENST00000549385.5; ENST00000423828.5; ENST00000267115.10; ENST00000547798.1
External Link	RMBase: Nm_site_1329

Ref 1	RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent. J Exp Clin Cancer Res. 2021 Feb 26;40(1):80. doi: 10.1186/s13046-021-01871-4.
Ref 2	Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitro. Br J Clin Pharmacol. 2004 Sep;58(3):277-87. doi: 10.1111/j.1365-2125.2004.02156.x.
Ref 3	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 4	Base-Resolution Mapping Reveals Distinct m(1)A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts. Mol Cell. 2017 Dec 7;68(5):993-1005.e9. doi: 10.1016/j.molcel.2017.10.019. Epub 2017 Nov 5.
Ref 5	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 6	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 7	R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
Ref 8	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 9	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 10	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 11	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 12	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 13	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 14	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 15	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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