General Information of the m6A Target Gene (ID: M6ATAR00018)
Target Name mmu-miR-365-3p
Gene Name mmu-miR-365-3p
miRBase ID
MIMAT0000711
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
mmu-miR-365-3p can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Regulator
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Methyltransferase-like 3 (METTL3) [WRITER]
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary METTL3 positively modulated the mmu-miR-365-3p processing in a microprocessor protein DiGeorge critical region 8-dependent manner.METTL3-mediated m6A modification in nociceptive sensitization and provide a novel perspective on m6A modification in the development of Inflammatory pain.
Target Regulation Up regulation
Responsed Disease Chronic pain ICD-11: MG30
Pathway Response MicroRNAs in cancer hsa05206
Cell Process RNA stability
Chronic pain [ICD-11: MG30]
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary METTL3 positively modulated the mmu-miR-365-3p processing in a microprocessor protein DiGeorge critical region 8-dependent manner.METTL3-mediated m6A modification in nociceptive sensitization and provide a novel perspective on m6A modification in the development of Inflammatory pain.
Responsed Disease Chronic pain [ICD-11: MG30]
Target Regulator Methyltransferase-like 3 (METTL3) WRITER
Target Regulation Up regulation
Pathway Response MicroRNAs in cancer hsa05206
Cell Process RNA stability
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: Methyltransferase-like 3 (METTL3)
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05411
Epigenetic Regulator mmu-miR-365-3p
Crosstalk relationship m6A → ncRNA
Disease Chronic pain
References
Ref 1 METTL3 regulates inflammatory pain by modulating m(6)A-dependent pri-miR-365-3p processing. FASEB J. 2020 Jan;34(1):122-132. doi: 10.1096/fj.201901555R. Epub 2019 Nov 19.