m6A-centered Crosstalk Information

Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT05411
 [1]
m6A modification mmu-miR-365-3p mmu-miR-365-3p METTL3 Methylation : m6A sites Direct Enhancement Non-coding RNA pri-miR-365-3p Regulated Target  lncRNA       miRNA   circRNA
m6A Modification:
m6A Regulator Methyltransferase-like 3 (METTL3) WRITER
 Regulator Info 
m6A Target mmu-miR-365-3p
 Targert Gene 
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type Non-coding RNA (ncRNA)
Epigenetic Regulator mmu-miR-365-3p microRNA View Details
Crosstalk Relationship m6A  →  ncRNA Enhancement
Crosstalk Mechanism m6A regulators directly modulate the functionality of ncRNAs through specific targeting ncRNA
Crosstalk Summary METTL3 positively modulated the mmu-miR-365-3p processing in a microprocessor protein DiGeorge critical region 8-dependent manner.METTL3-mediated m6A modification in nociceptive sensitization and provide a novel perspective on m6A modification in the development of Inflammatory pain.
Responsed Disease Chronic pain ICD-11: MG30
 Disease Info 
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
MG30: Chronic pain 293 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name Morphine Approved [2]
Synonyms
Avinza; Kadian; Morphine Sulfate; Depodur; Astramorph Pf; Duramorph Pf; Infumorph; Ms Contin; Oramorph Sr
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CID: 5288826
TTD: D0WE3O
DrugBank: DB00295
 Compound Name Ketoprofen Approved [3]
Synonyms
Actron; Alrheumat; Alrheumum; Alrheumun; Aneol; Capisten; Dexal; Epatec; Fastum; Kefenid; Ketoprofene; Ketoprofeno; Ketoprofenum; Ketopron; Ketoprophene; Lertus; Menamin; Meprofen; Orudis; Orugesic; Oruvail; Oscorel; Profenid; Toprec; Toprek; Benzoylhydratropic Acid; Orudis KT; K 1751; RP 19583; RP19583; RU 4733; Arthril (TN); Fastum (TN); Fastum Gel (TN); Iso-K; Keto (TN); Ketoflam (TN); Ketomex (TN); Ketonal (TN); Ketoprofenas (TN); Ketoprofene (TN); Ketoprofene [INN-French]; Ketoprofeno [INN-Spanish]; Ketoprofenum (TN); Ketoprofenum [INN-Latin]; Ketorin (TN); Ketospray (TN); Lasonil (TN); M-Benzoylhydratropic acid; Oki (TN); Orudis (TN); Oruvail (TN); RP-19583; Racemic-Ketoprofen; Zon (TN); Bi-Profnid (TN); RP, 19,583; Ketoprofen (JP15/USP/INN); Ketoprofen [USAN:INN:BAN:JAN]; Orudis, Oruvail, Ketoflam, Orudis KT, Ketoprofen; Acide (benzoyl-3-phenyl)-2-propionique; Acide (benzoyl-3-phenyl)-2-propionique [French]; L'Acide (benzoyl-3-phenyl)-2-propionique; (+-)-m-Benzoylhydratropic acid; 2-(3-Benzoylphenyl)propanoic acid; 2-(3-Benzoylphenyl)propionic acid; 2-(m-Benzoylphenyl)propionic acid; 2-[3-(benzoyl)phenyl]propanoic acid; 2-[3-(phenylcarbonyl)phenyl]propanoic acid; 2-[3-Benzoylphenyl]propionic acid; 3-Benzoylhydratropic acid
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CID: 3825
TTD: D0W9WF
DrugBank: DB01009
 Compound Name Strontium Chloride Sr-89 Approved [2]
Synonyms
Metastron
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CID: 5388879
TTD: D0R6HN
DrugBank: DB09498
 Compound Name Alpha 1-PI Withdrawn from market [4]
Synonyms
Ifenprodil; 23210-56-2; Vadilex; ifenprodil tartrate; Dilvax; Creocral; 4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol; Ifenprodil [INN:DCF]; RC 61-91; Ifenprodilum [INN-Latin]; UNII-R8OE3P6O5S; EINECS 245-491-4; R8OE3P6O5S; CHEMBL305187; 4-Benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol; 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propanol; 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol; NCGC00024643-03; IFENPRODIL HEMITARTRATE; alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine
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CID: 3689
TTD: D0I0DL
DrugBank: DB08954
 Compound Name Fentanyl Approved [5]
Synonyms
Fentanil; Phentanyl; Fentora; Sublimaze; Fentanila; Fentanest; Duragesic; Fentanylum; Durogesic; Sentonil; 437-38-7; Duragesic-100; IONSYS; Duragesic-25; Duragesic-75; Duragesic-50; Duragesic-12; Fentanyl-25; Fentanyl-75; Fentanyl-12; Fentanyl-50; Fentanylum [INN-Latin]; Fentanila [INN-Spanish]; Fentanyl-100; 1-Phenethyl-4-N-propionylanilinopiperidine; Matrifen; Sublimase; N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide; N-(1-Phenethyl-4-piperidyl)propionanilide; N-Phenethyl-4-(N-propionylanilino)piperidine; Fentanil [DCIT]; Subsys; Fentanyl-37; Fentanyl-62; Fentanyl-87; Abstral; Actiq; Lazanda; Onsolis; Fentanyl Citrate; Fentanyl Citrate Preservative Free; Sublimaze Preservative Free; fentanyl (transmucosal film, pain), Auxilium Pharmaceuticals
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CID: 3345
TTD: D0E1WI
DrugBank: DB00813
 Compound Name Phenylbutazone Approved [6]
Synonyms
Alindor; Alkabutazona; Alqoverin; Anerval; Anpuzone; Antadol; Anuspiramin; Arthrizon; Artizin; Artrizin; Artrizone; Artropan; Azdid; Azobutyl; Azolid; Benzone; Betazed; Bizolin; Bunetzone; Busone; Butacompren; Butacote; Butadion; Butadiona; Butadione; Butadionum; Butagesic; Butalgina; Butalidon; Butaluy; Butaphen; Butapirazol; Butapirazole; Butapyrazole; Butarecbon; Butartril; Butartrina; Butatron; Butazina; Butazolidin; Butazolidine; Butazona; Bute; Butidiona; Butone; Butoz; Butylpyrin; Buvetzone; Buzon;Chembutazone; Cotylbutazone; Digibutina; Diossidone; Diozol; Diphebuzol; Diphenylbutazone; Ecobutazone; Elmedal; Equipalazone; Equiphen; Eributazone; Esteve; Febuzina; Fenartil; Fenibutal; Fenibutasan; Fenibutazona; Fenibutol; Fenilbutazon; Fenilbutazona; Fenilbutazone; Fenilbutina; Fenilbutine; Fenilidina; Fenotone; Fenylbutazon; Flexazone; Intalbut; Intrabutazone; Intrazone; Ipsoflame; Kadol; Lingel; Malgesic; Mephabutazon; Mephabutazone; Merizone; Nadazone; Nadozone; Novophenyl; Phebuzin; Phebuzine; Phenbutazol; Phenbutazone; Phenopyrine; Phenylbutaz; Phenylbutazon; Phenylbutazonum; Phenyzene; Phenyzone; Praecirheumin; Pyrabutol; Pyrazolidin; Rectofasa; Reudo; Reudox; Reumasyl; Reumazin; Reumazol; Reumune; Reumuzol; Reupolar; Robizone; Rubatone; Scanbutazone; Schemergen; Schemergin; Shigrodin; Tazone; Tencodyne; Tetnor; Tevcodyne; Therazone; Ticinil; Todalgil; Uzone; Wescozone; Zolaphen; Zolidinum; Alka Butazolidin; Art rizin; Buta phen; Butyl pyrin; Equi bute; Exrheudon N; Fe nilbutine; Fenilbutazone [DCIT]; Phenyl butazone; Phenylbutazon [German]; Pirarreumol B; A 7514; Bizolin 200; G 13871; P 8386; P1686; P1Z; AZOLID (TN); Apo-Phenylbutazone; Butiwas-Simple; Component of Azolid-A; DA-192; Fenilbutazona [INN-Spanish]; G 13,871; Ia-But; Mepha-Butazon; Neo-zoline; Phenyl-Mobuzon; Phenylbutazonum [INN-Latin]; Robizon-V; Robizone-V; Usaf ge-15; VAC-10; B.T.Z; Phen-Buta-Vet; R-3-ZON; B.t.z.; Bute, Butazolidin, Butatron, Phenylbutazone; Phenylbutazone (JP15/USP/INN); Phenylbutazone [USAN:INN:BAN:JAN]; 1,2-Diphenyl-2,3-dioxo-4-N-butylpyrazoline; 1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine; 1,2-Diphenyl-4-butyl-3,5-dioxopyrazolidine; 1,2-Diphenyl-4-butyl-3,5-pyrazolidinedione; 1,2-diphenyl-3,5-dioxo-4-n-butylpyrazoline; 3,5-Dioxe-4 buty-1, diphenyl-pyrazolidine; 3,5-Dioxo-1,2-diphenyl-4-N-butylpyrazolidine; 3,5-Dioxo-1,2-diphenyl-4-n-butyl-pyrazolidin; 3,5-dioxo-4-butyl-1-diphenyl-pyrazolidine; 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE; 4-Butyl-1,2-diphenyl-3,5-dioxopyrazolidine; 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione; 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione; 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione
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CID: 4781
TTD: D07VHR
DrugBank: DB00812
 Compound Name Samarium Sm-153 Lexidronam Pentasodium Approved [2]
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CID: 9810246
TTD: D04YHR
DrugBank: DB09509
 Compound Name Hydromorphone Approved [7]
Synonyms
Dihydromorphinone; Dimorphone; Idromorfone; Hydromorphon; Dihydromorfinon; Hydromorfona; Laudacon; DiMo; Hydromorphonum; 7,8-Dihydromorphinone; Novolaudon; Hidromorfona; Dilaudid; Dilaudid Oros; Hydromorfona [Spanish]; Dihydromorfinon [Czech]; 466-99-9; Hydromorphonum [INN-Latin]; Hidromorfona [INN-Spanish]; Palladone; 6-Deoxy-7,8-dihydro-6-oxomorphine; Morphinone, dihydro-; Idromorfone [DCIT]; Laudicon; Hydromorphone [INN:BAN]; Dilaudid-hp; 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one; Hydromorphone HCL; Dilaudid (TN); Hydromorphone (INN); Palladone (TN); Palladone SR (TN); Morphinan-6-one, 4,5alpha-epoxy-3-hydroxy-17-methyl-(8CI); (-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one; (-)-Hydromorphone; (5alpha)-3-hydroxy-17-methyl-4,5-epoxymorphinan-6-one; 3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one; 4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone; Hydromorphone prodrug
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CID: 5284570
TTD: D04JHN
DrugBank: DB00327
 Compound Name Ethanol Approved [8]
Synonyms
Aethanol; Aethylalkohol; Alcohol; Alcohols; Algrain; Alkohol; Anhydrol; EOH; EOX; EtOH; Etanol; Etanolo; Ethicap; Ethylalcohol; Ethylol; Hinetoless; Hydroxyethane; Jaysol; Methylcarbinol; QMHAIh; Sekundasprit; Spirit; Spirt; Synasol; Tecsol; Thanol; Absolute alcohol; Absolute ethanol; Aethanol [German]; Alcare Hand Degermer; Alcohol [USP]; Alcohol anhydrous; Alcohol dehydrated; Alcohol etilico; Alcool ethylique; Alcool etilico; Alkohol [German]; Alkoholu etylowego; Anhydrous alcohol; Anhydrous ethanol; Cologne Spirit; Colognespirits; Dehydrated alcohol; Dehydrated ethanol; Denatured alcohol; Denatured ethanol; Desinfektol EL; Distilled spirits; Etanolo [Italian]; Ethanol Absolute; Ethanol Absolute Bp; Ethanol Anhydrous; Ethanol Extra Pure; Ethanol Vapor; Ethanol [JAN]; Ethanol solution; Ethanolum anhydricum; Ethyl alc; Ethyl alcohol; Ethyl alcohol usp; Ethyl hydrate; Ethyl hydroxide; Ethylalcohol [Dutch]; Ethyloxy Group; Etylowy alkohol; Fermentation alcohol; Grain alcohol; HYDROXYETHYL GROUP; Infinity Pure; Jaysol S; Methylated spirit; Molasses alcohol; Oxydimethylene Group; Potato alcohol; Reagent Alcohol; SY Fresh M; Spirits of wine; Spiritus vini; Tecsol C; AHD 2000; Anhydrol PM 4085; CDA 19; E7148_ALDRICH; Esumiru WK 88; Ethanol 200 proof; IMS 99; LTBB002977; SDA 3A; Alcohol (USP); Alcohol, Absolute; Alcohol, Grain; Alcohol, anhydrous; Alcohol, dehydrated; Alcohol, diluted; Alcohol, ethyl; Alcohols, C30; CDA 19-200; Ethanol (9CI); Ethanol, undenatured; Ru-Tuss Expectorant; SDA 40-2; SDM No. 37; ALCOHOL 5% IN D5-W; Alcohols, C1-3; Alcohols, C6-9; (C6-C9)Alkyl alcohol; 1-Hydroxyethane; 100C.NPA
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CID: 702
TTD: D00AMQ
DrugBank: DB00898
 Compound Name Mirogabalin Phase 3 [7]
Synonyms
1138245-13-2; UNII-S7LK2KDM5U; DS-5565; S7LK2KDM5U; Bicyclo[3.2.0]hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, (1R,5S,6S)-; Bicyclo(3.2.0)hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, (1R,5S,6S)-; 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid; ((1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo(3.2.0)hept-3-en-6-yl)acetic acid; Mirogabalin [INN]; Mirogabalin [USAN:INN]; [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid; DS5565; DS 5565; GTPL8303
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CID: 59509752
TTD: D07VFD
DrugBank: DB11825
 Compound Name Dihydrocodeine Phase 4 [9]
Synonyms
Dihydrocodeine bitartrate; DF 118; Dihydrocodeine (oral); S-8115; Dihydrocodeine (oral), Shionogi; (-)-Dihydrocodeine
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CID: 5284543
TTD: D0T6RC
DrugBank: DB01551
 Compound Name GSK2696273 Preregistration [10]
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TTD: D0F4QV
 Compound Name Egalet-002 Phase 3 [7]
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TTD: D0R8FL
 Compound Name Fulranumab Phase 3 [11]
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TTD: D0O1GS
 Compound Name Nabiximols Phase 3 [12]
Synonyms
Sativex; GW-1000; Cannador; Nabiximols [USAN]; GW1000; GW 1000; Tetrahydrocannabinol-cannabidiol combination; Cannabidiol mixture with Tetrahydrocannabinol; delta-9-Tetrahydrocannabinol and cannabidiol; Cannabidiol and delta-9-tetrahydrocarnabinol; GW-1000-02
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CID: 44148067
TTD: D0C5CE
 Compound Name Tanezumab Phase 3 [13]
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TTD: D00BVS
 Compound Name CR-845 Phase 2 [7]
Synonyms
Kappa opioid agonist (intravenous, pain), Cara/Ferring; Kappa opioid agonist (oral, pain), Cara/Ferring; Kappa opioid agonist (subcutaneous, pain), Cara/Ferring; CR-845 (iv infusion, pain), Cara/Ferring; CR-845 (oral capsule, pain), Cara/Ferring; CR-845 (subcutaneous, pain), Cara/Ferring; FE-202845 (iv, pain), Cara/Ferring; FE-202845 (oral, pain), Cara/Ferring; FE-202845 (sc, pain), Cara/Ferring
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TTD: D08NJE
 Compound Name LY3556050 Phase 2 [14]
Synonyms
(1R,5S,6R)-N-{2-methyl-1-[(3-methylpyridin-2-yl)oxy]propan-2-yl}-3-azabicyclo[3.1.0]hexane-6-carboxamide; 1638588-92-7; AT36106; BDBM311911; EN300-1700347; LY3556050; SCHEMBL16252692; US10166214, Example 47; Z3071648657
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CID: 86294067
TTD: DXE53Z
 Compound Name A277 Phase 2 [15]
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TTD: DDQH94
 Compound Name LY3526318 Phase 2 [16]
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TTD: D40GBC
 Compound Name V120083 Phase 2 [7]
Synonyms
S120083
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TTD: D0X3JK
 Compound Name XEN-2174 Phase 2 [17]
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TTD: D0U2XU
 Compound Name Dapansutrile Phase 2 [7]
Synonyms
54863-37-5; OLT1177; UNII-2Z03364G96; 2Z03364G96; Dapansutrile [INN]; Dapansutrile [USAN:INN]; Dapansutrile (USAN/INN); 3-Methylsulfonylpropionitrile; 3-methanesulfonylpropanenitrile; 3-methylsulphonyl-propionitrile; SCHEMBL9934796; CHEMBL3989943; LQFRYKBDZNPJSW-UHFFFAOYSA-N; MolPort-008-545-498; ZINC32005410; Propanenitrile, 3-(methylsulfonyl)-; AKOS010140086; D10920; Z2719319073
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CID: 12714644
TTD: D0TH5H
 Compound Name Flupirtine Phase 2 [18]
Synonyms
56995-20-1; Flupirtine [INN:BAN]; Flupirtinum [INN-Latin]; Flupirtino [INN-Spanish]; UNII-MOH3ET196H; C15H17FN4O2; EINECS 260-503-8; MOH3ET196H; JUUFBMODXQKSTD-UHFFFAOYSA-N; ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate; D 9998; flupirtin maleate; ethyl 2-amino-6-(4-fluorobenzylamino)pyridin-3-ylcarbamate; Flupirtinum; Flupirtino; MLS002153180; Carbamic acid, (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)-, ethyl ester; NCGC00015451-03; SMR001230672; Flupirtin; Carbamic acid, [2-ami
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CID: 53276
TTD: D0SD9V
DrugBank: DB06623
 Compound Name ABT-652 Phase 2 [19]
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TTD: D0S5BV
 Compound Name BMS-690514 Phase 2 [20]
Synonyms
BMS 690514; BMS690514
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CID: 11349170
TTD: D0R6UV
DrugBank: DB11665
 Compound Name PF-05089771 Phase 2 [21]
Synonyms
Nav1.7 blockers (pain), Pfizer; SCN9A blockers (pain), Pfizer/Icagen/Birkbeck; Voltage-gated sodium channel 1.7 blockers (pain), Pfizer
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CID: 46840946
TTD: D0O7QA
DrugBank: DB14856
 Compound Name EB-001 Phase 2 [7]
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TTD: D0O1VU
 Compound Name Omnitram Phase 2 [7]
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TTD: D0KZ3Q
 Compound Name NP-2 gene therapy Phase 2 [22]
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TTD: D06ZQL
 Compound Name PF-06372865 Phase 2 [23]
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CID: 76287260
TTD: D06TQR
 Compound Name Resiniferatoxin Phase 1 [7]
Synonyms
Reciniferatoxin; UNII-A5O6P1UL4I; A5O6P1UL4I; 57444-62-9; RTX; [3H]resiniferatoxin; 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)daphnetoxin 20-(3-hydroxy-5-methoxybenzeneacetate); CHEMBL448382; resinferatoxin; Benzeneacetic acid, 4-hydroxy-3-methoxy-, ((2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno(5,4-e)-1,3-benzodioxol-5-yl)methyl ester; Resiniferatoxin(RTX); CHEMBL17976
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CID: 5702546
TTD: D05XJW
DrugBank: DB06515
 Compound Name REL-1015 Phase 2 [7]
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TTD: D03RYJ
 Compound Name Neramexane Phase 2 [24]
Synonyms
Neramexane [INN]; Mrz 2579; MRZ 2-579; 1,3,3,5,5-Pentamethylcyclohexanamine; 1,3,3,5,5-pentamethylcyclohexan-1-amine
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CID: 6433106
TTD: D01KMR
DrugBank: DB04926
 Compound Name COL-195 Phase 1/2 [7]
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TTD: D0XB8Y
 Compound Name REL-1028 Phase 1 [7]
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TTD: D0XD0N
 Compound Name CNTX-0290 Phase 1 [7]
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TTD: D0U0CF
 Compound Name Egalet-004 Phase 1 [7]
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TTD: D0R9WD
 Compound Name TRV734 Phase 1 [7]
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TTD: D0OK6F
 Compound Name CA-011 Phase 1 [7]
Synonyms
2-Amino-4-(p-nitrophenyl)thiazole; 4-(4-Nitrophenyl)-1,3-thiazol-2-amine; 2-Amino-4-(4-nitrophenyl)thiazole; 4-(4-Nitrophenyl)-2-thiazolamine; 2-Thiazolamine, 4-(4-nitrophenyl)-; 4-(4-nitrophenyl)thiazol-2-amine; THIAZOLE, 2-AMINO-4-(p-NITROPHENYL)-; 4-(4-Nitrophenyl)thiazol-2-ylamine; 2-amino-4-(4'-nitrophenyl)-1,3-thiazole; RIKJWJIWXCUKQV-UHFFFAOYSA-N; BRN 0200321; 4-(4-Nitro-phenyl)-thiazol-2-ylamine; AI3-62320; 4-(4-nitrophenyl)-1,3-thiazole-2-ylamine; DSSTox_CID_65; AC1L27WX; Cambridge id 5156331; DSSTox_RID_
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CID: 16420
TTD: D0KK9D
 Compound Name PF-06305591 Phase 1 [25]
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CID: 71666749
TTD: D0K9IF
DrugBank: DB12106
 Compound Name OX-27 Phase 1 [26]
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TTD: D0J9GR
 Compound Name DWJ-208 Phase 1 [27]
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TTD: D0G0ER
 Compound Name JNJ-39439335 Phase 1 [28]
Synonyms
Mavatrep; 956274-94-5; UNII-F197218T99; F197218T99; Mavatrep [USAN:INN]; Mavatrep (USAN); JNJ 39439335; SCHEMBL1796599; SCHEMBL1797450; CHEMBL2364618; Mavatrep(JNJ-39439335); DTXSID90241905; BCP23936; EX-A2266; ZINC43175494; BDBM50086717; AKOS030527038; DB12875; CS-4591; SB17026; trans-2-(2-(2-(2-(4-Trifluoromethylphenyl)vinyl)-1H-benzimidazol-5-yl)phenyl)propan-2-ol; BC600772; HY-16935; B5930; J3.561.747G; D10370
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CID: 17751090
TTD: D0EM4S
DrugBank: DB12875
 Compound Name ABT-110 Phase 1 [29]
Synonyms
Hu-alphaD11; PG-110; Humanized anti-NGF antibody (pain), Lay Line Genomics; Humanized anti-NGF antibody (pain), PanGenetics; Humanized anti-nerve growth factor antibody (pain), Lay Line Genomics; Humanized anti-nerve growth factor antibody (pain), PanGenetics
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TTD: D03APM
 Compound Name Debio 0827 Phase 1 [30]
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CID: 16123252
TTD: D02HUY
 Compound Name GDC0310 Phase 1 [7]
Synonyms
RG6029; FCTMRPTVPHVTTN-UHFFFAOYSA-N; SCHEMBL16770884; BDBM71258; BCP25347; US9694002, 346; 1788066-71-6
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CID: 118120526
TTD: D01FZZ
 Compound Name PF614 Phase 1 [7]
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TTD: D00SBU
 Compound Name ABT-102 Phase 1 [31]
Synonyms
3-(1H-indazol-4-yl)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)urea
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CID: 11256560
TTD: D00CMV
 Compound Name PMID25666693-Compound-68 Patented [32]
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CID: 23628075
TTD: D0ZZ8F
 Compound Name PMID25666693-Compound-152 Patented [32]
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CID: 44548476
TTD: D0ZS3E
 Compound Name PMID25666693-Compound-96 Patented [32]
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TTD: D0ZQ2W
 Compound Name PMID25666693-Compound-105 Patented [32]
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CID: 25027804
TTD: D0ZP2C
 Compound Name PMID25666693-Compound-18 Patented [32]
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CID: 25265637
TTD: D0ZM8H
 Compound Name Six-membered heterocyclic benzamide derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2015143654Example29
    Click to Show/Hide
External Link
TTD: D0ZE6H
 Compound Name PMID25666693-Compound-107 Patented [32]
External Link
CID: 51349201
TTD: D0ZE1M
 Compound Name PMID25666693-Compound-144 Patented [32]
External Link
CID: 67412556
TTD: D0Z5HH
 Compound Name PMID25666693-Compound-160 Patented [32]
External Link
TTD: D0Z4QQ
 Compound Name PMID25666693-Compound-151 Patented [32]
External Link
CID: 68324656
TTD: D0YU9B
 Compound Name PMID25666693-Compound-21 Patented [32]
External Link
TTD: D0YR4E
 Compound Name PMID28270021-Compound-WO2014078408Example26 Patented [33]
External Link
TTD: D0YN0I
 Compound Name PMID25666693-Compound-67 Patented [32]
External Link
CID: 23628014
TTD: D0YM1M
 Compound Name PMID25666693-Compound-64 Patented [32]
External Link
TTD: D0Y9ST
 Compound Name PMID25666693-Compound-100 Patented [32]
External Link
CID: 71480662
TTD: D0Y1SI
 Compound Name Azaindazole amide derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2014016434Example30
    Click to Show/Hide
External Link
TTD: D0Y1NH
 Compound Name PMID28270021-Compound-WO2013009582Example76 Patented [33]
External Link
TTD: D0Y0XJ
 Compound Name PMID25666693-Compound-161 Patented [32]
External Link
TTD: D0XX8R
 Compound Name N-acylpyrrolidine ether derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2016020784Example11
    Click to Show/Hide
External Link
TTD: D0X4LA
 Compound Name PMID25666693-Compound-39 Patented [32]
External Link
CID: 57335613
TTD: D0X1OO
 Compound Name N-acylpiperidine ether derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2015092610Example164
    Click to Show/Hide
External Link
TTD: D0X1LP
 Compound Name PMID25666693-Compound-120 Patented [32]
External Link
CID: 53477386
TTD: D0WX4W
 Compound Name PMID25666693-Compound-132 Patented [32]
External Link
CID: 66908117
TTD: D0WT1W
 Compound Name PMID25666693-Compound-91 Patented [32]
External Link
TTD: D0WJ8R
 Compound Name Imidazo pyridine derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2015200341Example96
    Click to Show/Hide
External Link
TTD: D0WI7N
 Compound Name PMID25666693-Compound-33 Patented [32]
External Link
CID: 71611619
TTD: D0W4AA
 Compound Name PMID28270021-Compound-WO2015042088Example12 Patented [33]
External Link
TTD: D0VD5J
 Compound Name Pyrazolo[1,5-a]pyridine derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2013088257Example240
    Click to Show/Hide
External Link
TTD: D0V9ZJ
 Compound Name PMID25666693-Compound-89 Patented [32]
External Link
TTD: D0V9RM
 Compound Name PMID25666693-Compound-36 Patented [32]
External Link
CID: 71611910
TTD: D0V3PI
 Compound Name Tri-substituted urea derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2013176970Example1
    Click to Show/Hide
External Link
TTD: D0UQ2G
 Compound Name Six-membered heterocyclic benzamide derivative 5 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148344Example152
    Click to Show/Hide
External Link
TTD: D0UN4M
 Compound Name PMID25666693-Compound-83 Patented [32]
External Link
CID: 11720246
TTD: D0UE9K
 Compound Name PMID25666693-Compound-45 Patented [32]
External Link
CID: 70816331
TTD: D0U8YZ
 Compound Name PMID28270021-Compound-WO2015042088Example11 Patented [33]
External Link
TTD: D0U5XI
 Compound Name PMID25666693-Compound-125 Patented [32]
External Link
CID: 53475699
TTD: D0U5ON
 Compound Name PMID25666693-Compound-54 Patented [32]
External Link
CID: 70816505
TTD: D0U5CQ
 Compound Name Pyrido[3,2-d]pyrimidine derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2012125668Example27
    Click to Show/Hide
External Link
TTD: D0U3RD
 Compound Name PMID25666693-Compound-38 Patented [32]
External Link
CID: 87087836
TTD: D0TZ2W
 Compound Name Five membered heterocyclic benzamide derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148350Example36
    Click to Show/Hide
External Link
TTD: D0T4CF
 Compound Name PMID28270021-Compound-WO2010077680 109 Patented [33]
External Link
TTD: D0T0HM
 Compound Name PMID25666693-Compound-16 Patented [32]
External Link
CID: 46191563
TTD: D0SD4G
 Compound Name Pyrrolo[2,3-d]pyrimidine derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2012137089cE-245677
    Click to Show/Hide
External Link
TTD: D0S0II
 Compound Name Pyrido[3,2-d]pyrimidine derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2012125668Example12
    Click to Show/Hide
External Link
TTD: D0RR8O
 Compound Name Pyrazolo[4,3-c]pyridine derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2014053965Example3
    Click to Show/Hide
External Link
TTD: D0RK6W
 Compound Name PMID25666693-Compound-139 Patented [32]
External Link
TTD: D0RC7L
 Compound Name PMID25666693-Compound-32 Patented [32]
External Link
TTD: D0R9RP
 Compound Name PMID25666693-Compound-14 Patented [32]
External Link
CID: 60202428
TTD: D0R8GA
 Compound Name PMID25666693-Compound-106 Patented [32]
External Link
CID: 51349065
TTD: D0R2VB
 Compound Name PMID25666693-Compound-122 Patented [32]
External Link
CID: 53476470
TTD: D0R2QV
 Compound Name PMID28270021-Compound-WO2014129431Example8-1 Patented [33]
External Link
TTD: D0QT8L
 Compound Name PMID25666693-Compound-81 Patented [32]
External Link
CID: 11706654
TTD: D0QP4N
 Compound Name PMID28270021-Compound-WO2010077680 201 Patented [33]
External Link
TTD: D0PY0G
 Compound Name PMID25666693-Compound-112 Patented [32]
External Link
CID: 70652314
TTD: D0PT0U
 Compound Name PMID25666693-Compound-129 Patented [32]
External Link
TTD: D0PJ8O
 Compound Name PMID25666693-Compound-43 Patented [32]
External Link
TTD: D0P9KJ
 Compound Name Pyrrolo[2,3-b]pyridine derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2008063888P-0171
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External Link
TTD: D0P8SR
 Compound Name PMID25666693-Compound-49 Patented [32]
External Link
CID: 71238636
TTD: D0P5SB
 Compound Name PMID25666693-Compound-57 Patented [32]
External Link
CID: 71537379
TTD: D0P0MR
 Compound Name PMID25666693-Compound-8 Patented [32]
External Link
CID: 66549082
TTD: D0ON4M
 Compound Name PMID25666693-Compound-75 Patented [32]
External Link
CID: 11598064
TTD: D0OC6A
 Compound Name PMID25666693-Compound-53 Patented [32]
External Link
CID: 70816499
TTD: D0OA1P
 Compound Name PMID25666693-Compound-63 Patented [32]
External Link
CID: 71534837
TTD: D0O9GI
 Compound Name Pyrazolo[4,3-h]quinazoline-3-carboxamide derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2010106028Milciclib (PHA-848125)
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External Link
TTD: D0O8SX
 Compound Name PMID25666693-Compound-6 Patented [32]
External Link
CID: 66549275
TTD: D0O7IQ
 Compound Name PMID25666693-Compound-92 Patented [32]
External Link
TTD: D0O6VU
 Compound Name PMID25666693-Compound-136 Patented [32]
External Link
CID: 58387639
TTD: D0O3TG
 Compound Name PMID25666693-Compound-86 Patented [32]
External Link
CID: 56949431
TTD: D0O0UG
 Compound Name Bicyclic heteroaryl benzamide derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148354Example41
    Click to Show/Hide
External Link
TTD: D0O0GZ
 Compound Name PMID25666693-Compound-157 Patented [32]
External Link
CID: 52949700
TTD: D0NV2M
 Compound Name PMID25666693-Compound-19 Patented [32]
External Link
CID: 25263543
TTD: D0NM3D
 Compound Name PMID25666693-Compound-142 Patented [32]
External Link
CID: 58387658
TTD: D0NH2M
 Compound Name PMID25666693-Compound-35 Patented [32]
External Link
TTD: D0NB5M
 Compound Name PMID25666693-Compound-7 Patented [32]
External Link
CID: 66551085
TTD: D0N9FJ
 Compound Name Bicyclic heteroaryl benzamide derivative 7 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148373Example36
    Click to Show/Hide
External Link
TTD: D0N6NG
 Compound Name PMID25666693-Compound-24 Patented [32]
External Link
TTD: D0N2UQ
 Compound Name PMID25666693-Compound-156 Patented [32]
External Link
CID: 24783142
TTD: D0N0TF
 Compound Name PMID25666693-Compound-146 Patented [32]
External Link
CID: 59730981
TTD: D0N0QN
 Compound Name Triazolo[4,3-b]pyridazine derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2012125667Example24
    Click to Show/Hide
External Link
TTD: D0MZ7K
 Compound Name PMID25666693-Compound-109 Patented [32]
External Link
CID: 11187857
TTD: D0MY3K
 Compound Name PMID25666693-Compound-47 Patented [32]
External Link
CID: 88995251
TTD: D0MU3S
 Compound Name PMID28270021-Compound-WO2015042088Example4 Patented [33]
External Link
TTD: D0M8VS
 Compound Name PMID25666693-Compound-29 Patented [32]
External Link
CID: 71599906
TTD: D0M4WY
 Compound Name PMID28270021-Compound-WO2016054807Example112 Patented [33]
External Link
TTD: D0LK8E
 Compound Name PMID25666693-Compound-162 Patented [32]
External Link
TTD: D0LA0Q
 Compound Name PMID25666693-Compound-137 Patented [32]
External Link
TTD: D0KM0W
 Compound Name PMID25666693-Compound-98 Patented [32]
External Link
CID: 71480662
TTD: D0KF3A
 Compound Name Bicyclic heteroaryl benzamide derivative 5 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148373Example104
    Click to Show/Hide
External Link
TTD: D0KC8X
 Compound Name PMID25666693-Compound-1 Patented [32]
External Link
CID: 68313317
TTD: D0KB2Z
 Compound Name PMID28270021-Compound-WO2010077680 495 Patented [33]
External Link
TTD: D0K6IM
 Compound Name PMID25666693-Compound-46 Patented [32]
External Link
TTD: D0K4SZ
 Compound Name PMID25666693-Compound-148 Patented [32]
External Link
CID: 59731038
TTD: D0K3KM
 Compound Name PMID25666693-Compound-155 Patented [32]
External Link
CID: 24782891
TTD: D0K3KE
 Compound Name PMID25666693-Compound-141 Patented [32]
External Link
CID: 53402973
TTD: D0K0ZI
 Compound Name PMID25666693-Compound-62 Patented [32]
External Link
CID: 71506872
TTD: D0JX4I
 Compound Name PMID25666693-Compound-147 Patented [32]
External Link
CID: 59731029
TTD: D0JT8B
 Compound Name PMID25666693-Compound-22 Patented [32]
External Link
TTD: D0JK2N
 Compound Name PMID25666693-Compound-31 Patented [32]
External Link
TTD: D0JC8L
 Compound Name PMID25666693-Compound-59 Patented [32]
External Link
CID: 71539690
TTD: D0J9CS
 Compound Name PMID28270021-Compound-WO2010077680 103 Patented [33]
External Link
TTD: D0J4CA
 Compound Name PMID25666693-Compound-52 Patented [32]
External Link
CID: 70816169
TTD: D0IU1H
 Compound Name PMID25666693-Compound-94 Patented [32]
External Link
TTD: D0IT4N
 Compound Name PMID25666693-Compound-27 Patented [32]
External Link
CID: 71599827
TTD: D0IR7H
 Compound Name PMID25666693-Compound-9 Patented [32]
External Link
CID: 66549271
TTD: D0IP5E
 Compound Name PMID25666693-Compound-48 Patented [32]
External Link
TTD: D0IN5E
 Compound Name PMID25666693-Compound-102 Patented [32]
External Link
TTD: D0IK1S
 Compound Name Bicyclic heteroaryl benzamide derivative 4 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148354Example99
    Click to Show/Hide
External Link
TTD: D0I9FU
 Compound Name PMID25666693-Compound-159 Patented [32]
External Link
TTD: D0I3ZW
 Compound Name PMID28270021-Compound-WO2013161919Example85-117 Patented [33]
External Link
TTD: D0I2OO
 Compound Name PMID25666693-Compound-20 Patented [32]
External Link
TTD: D0HS1D
 Compound Name Bicyclic heteroaryl benzamide derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148354Example21(R or S)
    Click to Show/Hide
External Link
TTD: D0HF1A
 Compound Name PMID25666693-Compound-11 Patented [32]
External Link
CID: 66549650
TTD: D0HE7X
 Compound Name PMID25666693-Compound-72 Patented [32]
External Link
CID: 11582721
TTD: D0H6CX
 Compound Name PMID25666693-Compound-80 Patented [32]
External Link
CID: 11656215
TTD: D0H4TR
 Compound Name Six-membered heterocyclic benzamide derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2015143654Example41
    Click to Show/Hide
External Link
TTD: D0H3ZG
 Compound Name PMID25666693-Compound-4 Patented [32]
External Link
CID: 66551282
TTD: D0GZ4G
 Compound Name PMID25666693-Compound-66 Patented [32]
External Link
CID: 23627957
TTD: D0GV5G
 Compound Name PMID25666693-Compound-143 Patented [32]
External Link
TTD: D0G6IQ
 Compound Name PMID25666693-Compound-55 Patented [32]
External Link
CID: 56836246
TTD: D0G3UV
 Compound Name PMID28270021-Compound-WO2010077680 481 Patented [33]
External Link
TTD: D0FL8A
 Compound Name Bicyclic heteroaryl benzamide derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148354Example33(R or S)
    Click to Show/Hide
External Link
TTD: D0F8BF
 Compound Name PMID25666693-Compound-65 Patented [32]
External Link
CID: 71238361
TTD: D0F5NQ
 Compound Name PMID25666693-Compound-15 Patented [32]
External Link
CID: 25263680
TTD: D0F4YX
 Compound Name PMID25666693-Compound-30 Patented [32]
External Link
CID: 71598766
TTD: D0F4DI
 Compound Name PMID25666693-Compound-101 Patented [32]
External Link
CID: 71609207
TTD: D0F3HP
 Compound Name PMID28270021-Compound-WO2010077680 803 Patented [33]
External Link
TTD: D0F2BF
 Compound Name PMID25666693-Compound-26 Patented [32]
External Link
CID: 71599484
TTD: D0EV3G
 Compound Name PMID25666693-Compound-118 Patented [32]
External Link
CID: 53386424
TTD: D0EH2T
 Compound Name Six-membered heterocyclic benzamide derivative 4 Patented [33]
Synonyms
PMID28270021-Compound-WO2015143654Example62
    Click to Show/Hide
External Link
TTD: D0EC4Z
 Compound Name PMID25666693-Compound-82 Patented [32]
External Link
TTD: D0EC3Z
 Compound Name PMID25666693-Compound-69 Patented [32]
External Link
CID: 23628077
TTD: D0E8UP
 Compound Name PMID25666693-Compound-110 Patented [32]
External Link
TTD: D0E0SA
 Compound Name Bicyclic heteroaryl benzamide derivative 8 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148373Example41(S)
    Click to Show/Hide
External Link
TTD: D0DY5R
 Compound Name PMID25666693-Compound-124 Patented [32]
External Link
CID: 53476472
TTD: D0DT7M
 Compound Name Pyrrolo[3,2-c]pyridine derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2014053968Example5
    Click to Show/Hide
External Link
TTD: D0DQ5G
 Compound Name Pyrazolo[1,5-a]pyridine derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2013088256Example59
    Click to Show/Hide
External Link
TTD: D0DN3Q
 Compound Name PMID25666693-Compound-130 Patented [32]
External Link
TTD: D0DI1R
 Compound Name PMID25666693-Compound-42 Patented [32]
External Link
CID: 70816270
TTD: D0DE5K
 Compound Name PMID25666693-Compound-78 Patented [32]
External Link
TTD: D0DE5I
 Compound Name PMID25666693-Compound-74 Patented [32]
External Link
CID: 11676921
TTD: D0DC4O
 Compound Name PMID25666693-Compound-108 Patented [32]
External Link
CID: 51349341
TTD: D0D4NX
 Compound Name PMID25666693-Compound-115 Patented [32]
External Link
CID: 88875843
TTD: D0D2CF
 Compound Name Five membered heterocyclic benzamide derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148350Example81
    Click to Show/Hide
External Link
TTD: D0CY3U
 Compound Name PMID25666693-Compound-76 Patented [32]
External Link
CID: 11532887
TTD: D0CX4C
 Compound Name PMID25666693-Compound-138 Patented [32]
External Link
TTD: D0CR0H
 Compound Name Tri-substituted urea derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2013176970Example2
    Click to Show/Hide
External Link
TTD: D0CG8N
 Compound Name PMID25666693-Compound-87 Patented [32]
External Link
CID: 56961050
TTD: D0C9FN
 Compound Name PMID25666693-Compound-12 Patented [32]
External Link
CID: 66549652
TTD: D0C8ZZ
 Compound Name PMID25666693-Compound-114 Patented [32]
External Link
CID: 89556774
TTD: D0C5NT
 Compound Name N-(phenylpyrazolyl)benzamide derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2013132376Example157
    Click to Show/Hide
External Link
TTD: D0C3RK
 Compound Name PMID25666693-Compound-10 Patented [32]
External Link
CID: 66551086
TTD: D0C1MZ
 Compound Name PMID28270021-Compound-WO2016054807Example80 Patented [33]
External Link
TTD: D0BO1H
 Compound Name PMID25666693-Compound-77 Patented [32]
External Link
CID: 11562798
TTD: D0B4NI
 Compound Name PMID25666693-Compound-51 Patented [32]
External Link
CID: 57335038
TTD: D0B0WJ
 Compound Name 3-amino-5-benzyl-substituted indazole derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2010106028Entrectinib (RXDX-101)
    Click to Show/Hide
External Link
TTD: D0AU4G
 Compound Name PMID25666693-Compound-153 Patented [32]
External Link
CID: 88937082
TTD: D0AQ3U
 Compound Name Pyrrolo[2,3-d]pyrimidine derivative 4 Patented [33]
Synonyms
PMID28270021-Compound-WO2012137089PF-06278121 (Example 9)
    Click to Show/Hide
External Link
TTD: D0AG2A
 Compound Name PMID25666693-Compound-113 Patented [32]
External Link
CID: 70652315
TTD: D0A8LU
 Compound Name PMID25666693-Compound-25 Patented [32]
External Link
CID: 71599909
TTD: D0A3XC
 Compound Name PMID25666693-Compound-34 Patented [32]
External Link
CID: 71611907
TTD: D0A0YI
 Compound Name PMID25666693-Compound-40 Patented [32]
External Link
CID: 66644325
TTD: D09ZWU
 Compound Name PMID25666693-Compound-128 Patented [32]
External Link
CID: 24758063
TTD: D09SMA
 Compound Name PMID25666693-Compound-79 Patented [32]
External Link
CID: 11677423
TTD: D09QXC
 Compound Name PMID25666693-Compound-84 Patented [32]
External Link
CID: 11613881
TTD: D08ZBB
 Compound Name PMID25666693-Compound-111 Patented [32]
External Link
TTD: D08YAL
 Compound Name PMID25666693-Compound-135 Patented [32]
External Link
CID: 58387673
TTD: D08UEC
 Compound Name PMID25666693-Compound-13 Patented [32]
External Link
CID: 66549649
TTD: D08ICT
 Compound Name PMID28270021-Compound-WO2016054807Example71 Patented [33]
External Link
TTD: D08CZY
 Compound Name PMID25666693-Compound-123 Patented [32]
External Link
CID: 53476471
TTD: D08CLA
 Compound Name N-acylpyrrolidine ether derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2016020784Example12
    Click to Show/Hide
External Link
TTD: D08BIH
 Compound Name PMID25666693-Compound-134 Patented [32]
External Link
CID: 11674039
TTD: D07XZR
 Compound Name PMID25666693-Compound-119 Patented [32]
External Link
CID: 53477385
TTD: D07XVL
 Compound Name Six-membered heterocyclic benzamide derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2015143654Example60
    Click to Show/Hide
External Link
TTD: D07VFQ
 Compound Name PMID25666693-Compound-131 Patented [32]
External Link
CID: 25094155
TTD: D07RYM
 Compound Name PMID25666693-Compound-127 Patented [32]
External Link
CID: 24759759
TTD: D07MNI
 Compound Name PMID28270021-Compound-WO2010077680 811 Patented [33]
External Link
TTD: D07KVL
 Compound Name PMID25666693-Compound-17 Patented [32]
External Link
TTD: D07JNJ
 Compound Name PMID25666693-Compound-117 Patented [32]
External Link
TTD: D07FWF
 Compound Name PMID25666693-Compound-50 Patented [32]
External Link
CID: 71237925
TTD: D07FIY
 Compound Name PMID25666693-Compound-56 Patented [32]
External Link
CID: 71238385
TTD: D07EGF
 Compound Name PMID25666693-Compound-41 Patented [32]
External Link
CID: 66644203
TTD: D07EAV
 Compound Name Bicyclic heteroaryl benzamide derivative 6 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148373Example111
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External Link
TTD: D07CPL
 Compound Name PMID25666693-Compound-85 Patented [32]
External Link
CID: 11671115
TTD: D07BZW
 Compound Name Bicyclic heteroaryl benzamide derivative 9 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148373Example42(R)
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External Link
TTD: D07AJO
 Compound Name PMID27998201-Compound-12 Patented [34]
External Link
TTD: D06XCD
 Compound Name PMID25666693-Compound-3 Patented [32]
External Link
CID: 66549466
TTD: D06VYF
 Compound Name PMID25666693-Compound-37 Patented [32]
External Link
CID: 49802515
TTD: D06JHW
 Compound Name Pyrrolo[2,3-b]pyridine derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2008063888P-0180
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External Link
TTD: D06GOT
 Compound Name PMID25666693-Compound-90 Patented [32]
External Link
TTD: D05ZWR
 Compound Name PMID25666693-Compound-28 Patented [32]
External Link
CID: 71580510
TTD: D05SWL
 Compound Name PMID25666693-Compound-116 Patented [32]
External Link
CID: 88875796
TTD: D05SMP
 Compound Name PMID25666693-Compound-99 Patented [32]
External Link
CID: 71498842
TTD: D05RBF
 Compound Name Six-membered heterocyclic benzamide derivative 7 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148344Example96
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External Link
TTD: D05MRY
 Compound Name PMID28270021-Compound-WO2014078408Example1 Patented [33]
External Link
TTD: D05AQT
 Compound Name PMID25666693-Compound-154 Patented [32]
External Link
CID: 88937150
TTD: D04TIU
 Compound Name N-acylpiperidine ether derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2015092610Example114
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External Link
TTD: D04RXX
 Compound Name Six-membered heterocyclic benzamide derivative 6 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148344Example59
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External Link
TTD: D04JCD
 Compound Name PMID25666693-Compound-93 Patented [32]
External Link
TTD: D04HCS
 Compound Name N-acylpiperidine ether derivative 6 Patented [33]
Synonyms
PMID28270021-Compound-WO2015092610Example9
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External Link
TTD: D04GCC
 Compound Name PMID25666693-Compound-44 Patented [32]
External Link
CID: 70816274
TTD: D04FRL
 Compound Name Five membered heterocyclic benzamide derivative 2 Patented [33]
Synonyms
PMID28270021-Compound-WO2015148350Example76
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External Link
TTD: D04BRW
 Compound Name PMID25666693-Compound-97 Patented [32]
External Link
TTD: D03ZOZ
 Compound Name PMID25666693-Compound-71 Patented [32]
External Link
CID: 23628017
TTD: D03YFL
 Compound Name PMID25666693-Compound-145 Patented [32]
External Link
CID: 67412506
TTD: D03VXP
 Compound Name PMID25666693-Compound-88 Patented [32]
External Link
TTD: D03SHM
 Compound Name PMID25666693-Compound-61 Patented [32]
External Link
TTD: D03QAW
 Compound Name PMID25666693-Compound-73 Patented [32]
External Link
CID: 11532940
TTD: D03FSF
 Compound Name PMID25666693-Compound-70 Patented [32]
External Link
CID: 58416270
TTD: D03EEA
 Compound Name N-acylpiperidine ether derivative 5 Patented [33]
Synonyms
PMID28270021-Compound-WO2015092610Example3
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External Link
TTD: D03BAY
 Compound Name PMID28270021-Compound-WO2013009582Example16 Patented [33]
External Link
TTD: D02ZQN
 Compound Name PMID25666693-Compound-23 Patented [32]
External Link
TTD: D02QJE
 Compound Name N-acylpiperidine ether derivative 7 Patented [33]
Synonyms
PMID28270021-Compound-WO2016009296Example15
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External Link
TTD: D02OLJ
 Compound Name PMID25666693-Compound-5 Patented [32]
External Link
TTD: D02OAH
 Compound Name PMID25666693-Compound-140 Patented [32]
External Link
CID: 23585453
TTD: D02JQB
 Compound Name Pyrrolo[2,3-b]pyridine derivative 3 Patented [33]
Synonyms
PMID28270021-Compound-WO2010129570P-2061
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External Link
TTD: D02IBX
 Compound Name PMID28270021-Compound-WO2014152663 701 Patented [33]
External Link
TTD: D02ETU
 Compound Name PMID25666693-Compound-126 Patented [32]
External Link
CID: 53475700
TTD: D02EKO
 Compound Name PMID25666693-Compound-104 Patented [32]
External Link
CID: 25104368
TTD: D01RUK
 Compound Name PMID25666693-Compound-58 Patented [32]
External Link
TTD: D01PLJ
 Compound Name PMID25666693-Compound-103 Patented [32]
External Link
TTD: D01LGQ
 Compound Name PMID25666693-Compound-158 Patented [32]
External Link
CID: 16742146
TTD: D01HED
 Compound Name PMID25666693-Compound-133 Patented [32]
External Link
CID: 25094231
TTD: D01GEK
 Compound Name PMID25666693-Compound-150 Patented [32]
External Link
CID: 68324561
TTD: D01DNH
 Compound Name PMID25666693-Compound-2 Patented [32]
External Link
CID: 66549276
TTD: D00YXA
 Compound Name N-acylpiperidine ether derivative 1 Patented [33]
Synonyms
PMID28270021-Compound-WO2015092610Example113
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External Link
TTD: D00XXZ
 Compound Name PMID25666693-Compound-60 Patented [32]
External Link
TTD: D00QEZ
 Compound Name PMID25666693-Compound-149 Patented [32]
External Link
TTD: D00OLY
 Compound Name PMID25666693-Compound-95 Patented [32]
External Link
TTD: D00ODY
 Compound Name PMID28270021-Compound-WO2016054807Example1 Patented [33]
External Link
TTD: D00MGO
 Compound Name PMID25666693-Compound-121 Patented [32]
External Link
CID: 53477387
TTD: D00KTN
 Compound Name N-acylpiperidine ether derivative 4 Patented [33]
Synonyms
PMID28270021-Compound-WO2015092610Example2
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External Link
TTD: D00FJH
 Compound Name PMID28270021-Compound-WO2016054807Example82 Patented [33]
External Link
TTD: D00EUL
 Compound Name Propiram fumarate Discontinued in Phase 3 [35]
Synonyms
Algeril; Diramax; Dirame; Diramine; Diratab; Propiram; FBA-4503
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External Link
CID: 6433584
TTD: D08LIF
 Compound Name AMG-517 Discontinued in Phase 1 [36]
Synonyms
AMG 517; BD-0082
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External Link
CID: 16007367
TTD: D0L5XI
 Compound Name BL-1827 Discontinued in Phase 1 [37]
External Link
TTD: D06MXY
 Compound Name SequestOx Application submitted [7]
Synonyms
Oxycodone / naltrexone; Naltrexone / oxycodone; Troxyca Er; Oxycodone hydrochloride / naltrexone hydrochloride; Naltrexone hydrochloride / oxycodone hydrochloride; Naltrexone hydrochloride and oxycodone hydrochloride; ALO-02; Naltrexone hydrochloride mixture with oxycodone hydrochloride; 850636-71-4; Oxycodone hydrochloride and naltrexone hydrochloride
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External Link
CID: 90479726
TTD: D0FU5Y
 Compound Name Remoxy ER Application submitted [7]
External Link
TTD: D0B7VH
 Compound Name Oxycodone hydrochloride Application submitted [7]
Synonyms
oxycodone ER
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External Link
CID: 5462350
TTD: D07WPQ
 Compound Name DBO-17 Terminated [38]
External Link
CID: 10042211
TTD: D0XH1H
 Compound Name DBO-11 Terminated [39]
Synonyms
166374-49-8; Naxifylline (USAN/INN)
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External Link
CID: 23724971
TTD: D0PE1A
 Compound Name ACEA-1328 Terminated [40]
External Link
CID: 9816093
TTD: D0O4JH
 Compound Name RO-25-6981 Terminated [41]
Synonyms
Ro 25-6981; CHEMBL305195; ro25-6981; 169274-78-6; 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol; 4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl)phenol; QEM; Tocris-1594; AC1O7H0A; Lopac0_001082; ZINC7042; SCHEMBL6159263; CHEBI:92897; HMS3268G13; EX-A1825; PDSP2_000361; BDBM50080029; CS-2011; CCG-205159; NCGC00025226-01; NCGC00025226-03; NCGC00025226-02; HY-13993; (AR,BS)-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL MALEATE; BRD-K51541829-001-01-3
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External Link
CID: 6604887
TTD: D0K0DB
 Compound Name THA-901 Investigative [42]
Synonyms
TH-901
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External Link
TTD: D06MEC
 Compound Name SP-SAP Investigative [43]
Synonyms
NK1-saporin conjugate, Advanced Targeting Systems; Neurokinin NK1-saporin conjugate, ATS; SP-SAP, APT; SP-SAP, Advanced Pain Therapeutics; SP-SAP, Advanced Targeting Systems; Substance P-saporin conjugate, ATS; Substance P-saporin conjugate, Advanced Targeting Systems
    Click to Show/Hide
External Link
TTD: D04LHG
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