m6A-centered Drug Response Information
General Information of the Drug (ID: M6ADRUG0252)
| Name |
Decitabine
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| Synonyms |
AzadC; Dacogen; Dezocitidine; NCGC_5ADOC; Dacogen (TN); E-7373; Decitabine (USAN/INN); Dacogen, 5-aza-2'-deoxycytidine,NSC 127716, Dacogen, DAC, Decitabine; 2'-Deoxy-5-azacytidine; 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one; 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one; 4-Amino-1-(2-deoxy-beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one; 5-AZAdC; 5-Aza-2′-Deoxycytidine; 5-Aza-2'-deoxycytidine; 5-Azadeoxycytidine; 5-Deoxy-2′-azacytidine; 5-aza-2-deoxycytidine; 5-aza-CdR; 5-aza-dC; 5A2dc
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| Structure |
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3D MOL
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| Formula |
C8H12N4O4
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| InChI |
InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1
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| InChIKey |
XAUDJQYHKZQPEU-KVQBGUIXSA-N
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Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
| In total 4 item(s) under this drug | ||
| Crosstalk ID: M6ACROT02106 | ||
| m6A Regulator | Methyltransferase-like 3 (METTL3) | |
| m6A Target | Cysteine methyltransferase DNMT3A (DNMT3A) | |
| Epigenetic Regulator | Cysteine methyltransferase DNMT3A (DNMT3A) | |
| Crosstalk relationship | m6A → DNA modification | |
| Disease | Gastric cancer | |
| Crosstalk ID: M6ACROT02107 | ||
| m6A Regulator | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) | |
| m6A Target | Cysteine methyltransferase DNMT3A (DNMT3A) | |
| Epigenetic Regulator | Cysteine methyltransferase DNMT3A (DNMT3A) | |
| Crosstalk relationship | m6A → DNA modification | |
| Disease | Gastric cancer | |
| Crosstalk ID: M6ACROT05961 | ||
| m6A Regulator | Methyltransferase-like 3 (METTL3) | |
| m6A Target | Cysteine methyltransferase DNMT3A (DNMT3A) | |
| Epigenetic Regulator | Long intergenic non-protein coding RNA 942 (LINC00942) | |
| Regulated Target | Methyltransferase-like protein 3 (METTL3) | |
| Crosstalk relationship | ncRNA → m6A | |
| Disease | Gastric cancer | |
| Crosstalk ID: M6ACROT05962 | ||
| m6A Regulator | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) | |
| m6A Target | Cysteine methyltransferase DNMT3A (DNMT3A) | |
| Epigenetic Regulator | Long intergenic non-protein coding RNA 942 (LINC00942) | |
| Regulated Target | Methyltransferase-like protein 3 (METTL3) | |
| Crosstalk relationship | ncRNA → m6A | |
| Disease | Gastric cancer | |