General Information of the Drug (ID: M6ADRUG0169)
Name
CP028
Synonyms
cp028, 347397-83-5, 1-(2-Ethylphenyl)-5-((5-(4-fluorophenyl)furan-2-yl)methylene) pyrimidine-2,4,6 (1H,3H,5H)-trione, 1-(2-ethylphenyl)-5-{(E)-1-[5-(4-fluorophenyl)-2-furyl]methylidene}-2,4,6(1H,3H,5H)-pyrimidinetrione, MFCD02624148, STK855704, AKOS001644857, AKOS005632311, (5E)-1-(2-ethylphenyl)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione, DA-62480, HY-136951, CS-0135545, (5E)-3-(2-ethylphenyl)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}-6-hydroxypyrimidine-2,4(3H,5H)-dione
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Structure
3D MOL
Formula
C23H17FN2O4
InChI
InChI=1S/C23H17FN2O4/c1-2-14-5-3-4-6-19(14)26-22(28)18(21(27)25-23(26)29)13-17-11-12-20(30-17)15-7-9-16(24)10-8-15/h3-13H,2H2,1H3,(H,25,27,29)/b18-13+
InChIKey
KKBJKSJVJPXCRA-QGOAFFKASA-N
PubChem CID
1926482
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
In total 2 item(s) under this drug
Crosstalk ID: M6ACROT05719
m6A Regulator YTH domain-containing protein 1 (YTHDC1)
m6A Target Circ_TET2
Epigenetic Regulator Circ_TET2
Regulated Target Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship m6A → ncRNA
Disease Chronic lymphocytic leukemia
Crosstalk ID: M6ACROT05722
m6A Regulator RNA binding protein X (RBMX)
m6A Target Circ_TET2
Epigenetic Regulator Circ_TET2
Regulated Target Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship m6A → ncRNA
Disease Chronic lymphocytic leukemia
References
Ref 1 Wilms' tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3Beta sequence associated with remission in one patient is detectable in other vaccinated patients. Cancer Immunol Immunother. 2012 Mar;61(3):313-22. doi: 10.1007/s00262-011-1099-y. Epub 2011 Sep 7.