m6A-centered Disease Response Information

General Information of the Disease (ID: M6ADIS0349)
Name
BackgroundAllergic rhinitis
ICD
ICD-11: CA08
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease
In total 2 item(s) under this disease
Crosstalk ID: M6ACROT05739
 Crosstalk Info 
m6A Regulator Methyltransferase-like 3 (METTL3)
 Regulator Info 
m6A Target Circ_MIRLET7BHG
 Target Gene 
Epigenetic Regulator Circ_MIRLET7BHG
Regulated Target Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1)
Crosstalk relationship m6A → ncRNA
Crosstalk ID: M6ACROT05919
 Crosstalk Info 
m6A Regulator Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
 Regulator Info 
m6A Target Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
 Target Gene 
Epigenetic Regulator Circ_MIRLET7BHG
Regulated Target Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1)
Crosstalk relationship ncRNA → m6A
References
Ref 1 The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3279-86. doi: 10.1158/1535-7163.MCT-07-0564. Epub 2007 Dec 7.
Ref 2 The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer. Mol Cancer Ther. 2015 Feb;14(2):384-94. doi: 10.1158/1535-7163.MCT-14-0428. Epub 2014 Dec 10.