m6A-centered Crosstalk Information

Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT05258
 [1], [2]
Non-coding RNA hsa_Circ_0072309 miR-607  lncRNA       miRNA   circRNA Indirect Enhancement m6A modification FAP FAP FTO Demethylation : m6A sites
m6A Modification:
m6A Regulator Fat mass and obesity-associated protein (FTO) ERASER
 Regulator Info 
m6A Target Prolyl endopeptidase FAP (FAP)
 Targert Gene 
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type Non-coding RNA (ncRNA)
Epigenetic Regulator hsa_circ_0072309 (Circ_LIFR) circRNA View Details
Regulated Target hsa-miR-607 View Details
Crosstalk Relationship ncRNA  →  m6A Enhancement
Crosstalk Mechanism ncRNAs indirectly impacts m6A modification through downstream signaling pathways
Crosstalk Summary Circ_LIFR interacted with hsa-miR-607 via its miRNA response element to upregulate the expression of FTO, an m6A demethylase and downstream target of miR-607, thus promoting tumorigenesis of NSCLC.FTO facilitated NSCLC metastasis by modifying the m6A level of Prolyl endopeptidase FAP (FAP) in a YTHDF2-dependent manner.FTO promoted cell migration and invasion in NSCLC, and the FAK inhibitor defactinib (VS6063) suppressed NSCLC metastasis induced by overexpression of FTO.
Responsed Disease Non-small cell lung cancer ICD-11: 2C25.Y
 Disease Info 
Responsed Drug VS-6063
 Drug Info 
In-vitro Model
 NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
NCI-H1650 Minimally invasive lung adenocarcinoma Homo sapiens CVCL_1483
NCI-H460 Lung large cell carcinoma Homo sapiens CVCL_0459
HCC827 Lung adenocarcinoma Homo sapiens CVCL_2063
PC-9 Lung adenocarcinoma Homo sapiens CVCL_B260
SK-MES-1 Lung squamous cell carcinoma Homo sapiens CVCL_0630
BEAS-2B Normal Homo sapiens CVCL_0168
In-vivo Model The Laboratory Animal Center of Soochow University provided female BALB/c nude mice (5 weeks old). Mice were kept under specific pathogen-free conditions. They were injected intravenously (i.v.) with FTO-overexpressing and control A549 cells (1.8 × 106 cells/mouse) to establish the in vivo model of NSCLC metastasis, and were then gavaged with dimethyl sulfoxide (DMSO) (25 mg/kg, daily) or the FAK inhibitor defactinib (VS6063) (Cat#S7654, Selleck, USA) (25 mg/kg, daily) beginning in the fifth week after injection. The mice were euthanized eight weeks after being inoculated, and their lungs were taken out and preserved in Bouin's solution for macroscopic investigation of metastatic nodules. Hematoxylin and eosin (H&E) staining of lung tissues was used to look for micrometastatic foci.
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
Prolyl endopeptidase FAP (FAP) 12 Compound(s) Regulating the Target Click to Show/Hide the Full List
 Compound Name Talabostat Phase 3 [3]
Synonyms
Talabostat mesylate; Boroproline compounds, DARA BioSciences; Boroproline compounds, Point Therapeutics; PT-100; Val-boro-Pro
    Click to Show/Hide
MOA Inhibitor
Activity IC50 = 66 nM
External Link
CID: 6918572
TTD: D0FQ2U
DrugBank: DB06182
 Compound Name BIBH 1 Phase 2 [4]
External Link
TTD: D0N7LA
 Compound Name Sibrotuzumab Phase 2 [4]
MOA Inhibitor
External Link
TTD: DVX3H0
 Compound Name RG7461 Phase 1 [5]
MOA Antagonist
External Link
TTD: D0V7GS
 Compound Name AMG 506 Phase 1 [6]
MOA Inhibitor
External Link
TTD: DN2F9A
 Compound Name NG-641 Phase 1 [7]
External Link
TTD: D1A8NU
 Compound Name FAP5-DM1 Preclinical [8]
External Link
TTD: DO7HS1
 Compound Name PT630 Preclinical [9]
MOA Inhibitor
External Link
TTD: D7K0GP
 Compound Name MIP-1231 Investigative [10]
Synonyms
MIP-1232; MIP-1233; MIP-1259; MIP-1260; MIP-1271; MIP-1272; Seprase inhibitors (cancer, imaging); Iodine-131-MIP-1232; Seprase inhibitors (cancer, imaging), Molecular Insight; FAP-alpha antagonists (cancer, imaging), Molecular Insight; Fibroblast-activating protein antagonists (cancer, imaging), Molecular Insight
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MOA Antagonist
External Link
TTD: D01HTS
 Compound Name FE-999040 Investigative [10]
Synonyms
FAP inhibitors, Vantia; Fibroblast activation protein inhibitors (sc/oral, cancer/pulmonary fibrosis/IBD), Vantia
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MOA Inhibitor
External Link
TTD: D0A9WW
 Compound Name VA-119930 Investigative [10]
Synonyms
Fibroblast activation protein inhibitors (IBD), Vantia; Seprase inhibitor (IBD), Vantia
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MOA Inhibitor
External Link
TTD: D0M9SD
 Compound Name ARI-3099 Investigative [11]
Synonyms
compound 6 [PMID: 23594271]; compound 226 [PMID: 24997602]; Py(D)AlaboroPro
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MOA Inhibitor
Activity Ki = 9 nM
External Link
CID: 71655266
TTD: D03DNV
2C25: Lung cancer 52 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name Adagrasib Approved [12]
Synonyms
2326521-71-3; MRTX-849; UNII-8EOO6HQF8Y; 8EOO6HQF8Y; 2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile; CHEMBL4594350; SCHEMBL20974691; GTPL10888; Kras G12C inhibitor MRTX849; BCP31538; EX-A3258; MRTX 849; MFCD32263433; s8884; compound 20 [PMID: 32250617]; BS-16211; HY-130149; CS-0105265; 2-Piperazineacetonitrile, 4-(7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2S)-1-methyl-2-pyrrolidinyl)methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2S)-
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External Link
CID: 138611145
TTD: DUQV41
 Compound Name Amivantamab Approved [13]
External Link
TTD: DQ5X1Z
 Compound Name Mobocertinib Approved [14]
Synonyms
1847461-43-1; TAK-788; TAK788; AP32788; UNII-39HBQ4A67L; 39HBQ4A67L; propan-2-yl 2-[4-{[2-(dimethylamino)ethyl](methyl)amino}-2-methoxy-5-(prop-2-enamido)anilino]-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate; Mobocertinib [INN]; Mobocertinib [USAN]; AP-32788; Mobocertinib (TAK788); Mobocertinib(TAK-788); SCHEMBL17373133; GTPL10468; BDBM368374; BCP31045; EX-A3392; US10227342, Example 10; MFCD32669806; NSC825519; s6813; TAK-788;AP32788; WHO 11183; NSC-825519; example 94 [WO2015195228A1]; HY-135815; CS-0114256; TAK-788;TAK 788; AP 32788; 5-Pyrimidinecarboxylic acid, 2-((4-((2-(dimethylamino)ethyl)methylamino)-2-methoxy-5-((1-oxo-2-propen-1-yl)amino)phenyl)amino)-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester; C(C=C)(=O)NC=1C(=CC(=C(C=1)NC1=NC=C(C(=N1)C1=CN(C2=CC=CC=C12)C)C(=O)OC(C)C)OC)N(C)CCN(C)C; Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate; Isopropyl 2-(5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenylamino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate; Propan-2-yl 2-(5-(acryloylamino)-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyanilino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate; propan-2-yl 2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate
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External Link
CID: 118607832
TTD: DI4HA7
 Compound Name Sugemalimab Approved in China [15]
External Link
TTD: DDZ48Y
 Compound Name Sacituzumab govitecan Approved [16]
Synonyms
1491917-83-9; 1535963-91-7; 1796566-95-4; CYSTEINYL CL2A-SN-38; DA64T2C2IO; DTXSID401335985; EX-A4354; F82944; GOVITECAN CYSTEINYL CONJUGATE; hRS 7SN38; hRS7-SN38; IMMU 132; IMMU-132; M9BYU8XDQ6; Sacituzumab govitecan; Sacituzumab govitecan [USAN]; sacituzumab-govitecan; Satralizumab linker; SN-38 CYSTEINYL CONJUGATE; UNII-M9BYU8XDQ6
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External Link
CID: 91668186
TTD: D8LAE2
 Compound Name Atezolizumab Approved [17]
External Link
TTD: D0YM2K
 Compound Name Tepotinib Approved [18]
Synonyms
1100598-32-0; EMD 1214063; UNII-1IJV77EI07; Tepotinib (EMD 1214063); EMD1214063; 1IJV77EI07; MSC-2156119J; Benzonitrile, 3-[1,6-dihydro-1-[[3-[5-[(1-methyl-4-piperidinyl)methoxy]-2-pyrimidinyl]phenyl]methyl]-6-oxo-3-pyridazinyl]-; C29H28N6O2; Tepotinib [INN]; Benzonitrile, 3-[1,6-Dihydro-1-[[3-[5-[(1-Methyl-4-Piperidinyl)Methoxy]-2-PyriMidinyl]Phenyl]Methyl]-6-Oxo-3-Pyridazinyl]; Benzonitrile, 3-(1,6-dihydro-1-((3-(5-((1-methyl-4-piperidinyl)methoxy)-2-pyrimidinyl)phenyl)methyl)-6-oxo
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External Link
CID: 25171648
TTD: D0R8QG
DrugBank: DB15133
 Compound Name Sotorasib Approved [19]
Synonyms
AMG-510; AMG510; AMG-510 racemate; 2252403-56-6; AMG 510; Kras G12C inhibitor 9; 2296729-00-3; UNII-2B2VM6UC8G; 2B2VM6UC8G; CHEMBL4535757; 2296729-00-3 (racemate); 4-((S)-4-Acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one; 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one; Sotorasib [INN]; 6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-((2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl)pyrido(2,3-d)pyrimidin-2-one; AMG510 racemate; Sotorasib [USAN]; AMG-510(racemate); Kras mutant-targeting AMG 510; SCHEMBL20560375; GTPL10678; AMG 510 pound>>AMG-510; AMY16918; BCP30452; BCP33368; EX-A3538; BDBM50514402; NSC818433; s8830; WHO 11370; DB15569; NSC-818433; BS-16684; HY-114277; CS-0081316; compound (R)-38 [PMID: 31820981]; (1m)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-(propan-2-yl)pyridin-3-yl)-4-((2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl)pyrido(2,3-d)pyrimidin-2(1H)-one; (1S)-4-((S)-4-Acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one; 2296729-66-1; Pyrido(2,3-d)pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-(1-methylethyl)-3-pyridinyl)-4-((2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl)-
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External Link
CID: 137278711
TTD: D0R7LD
DrugBank: DB15569
 Compound Name Entrectinib Approved [20]
Synonyms
1108743-60-7; RXDX-101; UNII-L5ORF0AN1I; Entrectinib (RXDX-101); L5ORF0AN1I; Benzamide, N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrahydro-2H-pyran-4-yl)amino]-; Benzamide, N-(5-((3,5-difluorophenyl)methyl)-1H-indazol-3-yl)-4-(4-methyl-1-piperazinyl)-2-((tetrahydro-2H-pyran-4-yl)amino)-; Entrectinib [USAN:INN]; YMX; Kinome_2659; Entrectinib(rxdx-101); Entrectinib (USAN/INN); SCHEMBL3512601; GTPL8290; CHEMBL1983268; KS-00000TSK
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External Link
CID: 25141092
TTD: D0O0LS
DrugBank: DB11986
 Compound Name Repotrectinib Approved [21]
Synonyms
FIKPXCOQUIZNHB-RRKGBCIJSA-N; SCHEMBL20438940; TPX 0005; BCP19778
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External Link
CID: 135565923
TTD: D05NFR
 Compound Name MYL-1402O Phase 3 [22]
Synonyms
bevacizumab biosimilar
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External Link
TTD: DYH3Q6
 Compound Name AB154 Phase 3 [23]
Synonyms
Domvanalimab
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External Link
TTD: DT1FS0
 Compound Name Datopotamab deruxtecan Phase 3 [24]
External Link
TTD: DP41HV
 Compound Name CS1001 Phase 3 [25]
External Link
TTD: D3MP1S
 Compound Name JDQ443 Phase 3 [26]
Synonyms
(S)-JDQ-443; 1-(6-((4S)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl)-2-azaspiro[3.3]heptan-2-yl)prop-2-en-1-one; 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-inda zol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]- 2-Propen-1-one; 1-[6-[(4R)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]-2-propen-1-one; 1-[6-[4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methylindazol-5-yl)pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one; 1-{6-[(4M)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5- methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2- azaspiro[3.3]heptan-2-yl}prop-2-en-1-one; 1-{6-[(4M)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl}prop-2-en-1-one; 2653994-08-0; 2653994-10-4; 2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]-; AKOS040757949; AT36708; BDBM50579985; CHEMBL5077861; compound 5 [PMID: 35404998]; CS-0226220; CS-0311034; EX-A5693; example 1a [WO2021120890A1]; GLXC-25533; GTPL11715; HY-139612A; JDQ 443; JDQ 443 [WHO-DD]; JDQ443; JDQ-443; MS-29737; NSC846146; NSC-846146; NVP-JDQ443; NVP-JDQ-443; Opnurasib; opnurasib [INN]; -PROPEN-1-ONE, 1-(6-((4R)-4-(5-CHLORO-6-METHYL-1H-INDAZOL-4-YL)-5-METHYL-3-(1-METHYL-1H-INDAZOL-5-YL)-1H-PYRAZOL-1-YL)-2-AZASPIRO(3.3)HEPT-2-YL)-; Q3W0H3V1LQ; SCHEMBL23533580
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CID: 156501355
TTD: D37IQM
 Compound Name TRS003 Phase 3 [27]
External Link
TTD: D2KVG4
 Compound Name Tusamitamab ravtansine Phase 3 [28]
Synonyms
SAR408701
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External Link
TTD: D2D6NJ
 Compound Name RG6058 Phase 3 [29]
Synonyms
Tiragolumab
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TTD: D0L4VD
 Compound Name GSK4069889 Phase 2 [30]
Synonyms
TSR-022
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External Link
TTD: DZW53X
 Compound Name APL-101 Phase 2 [31]
Synonyms
Bozitinib; PLB-1001; 1440964-89-5; Vebreltinib; Vebreltinib [USAN]; UNII-2WZP8A9VFN; 2WZP8A9VFN; Bozitinib (PLB-1001); SCHEMBL15594471; BDBM107096; CBI-3103; s6762; WHO 11677; HY-125017; CS-0088607; US9695175, 44; 1,2,4-Triazolo(4,3-b)pyridazine, 6-(1-cyclopropyl-1H-pyrazol-4-yl)-3-(difluoro(6- fluoro-2-methyl-2H-indazol-5-yl)methyl)-; 6-(1-Cyclopropyl-1H-pyrazol-4-yl)-3-(difluoro(6-fluoro-2-methyl-2H-indazol-5- yl)methyl)-1,2,4-triazolo(4,3-b)pyridazine
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External Link
CID: 72202701
TTD: DV3Y7F
 Compound Name SGN-LIV1A Phase 2 [32]
Synonyms
Ladiratuzumab Vedotin
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TTD: DS6B1L
 Compound Name BNT116 Phase 2 [33]
External Link
TTD: DR39GZ
 Compound Name AZD7789 Phase 2 [34]
External Link
TTD: DNI7E3
 Compound Name L-DOS47 Phase 1/2 [35]
External Link
TTD: DN3Z5D
 Compound Name NC318 Phase 2 [36]
External Link
TTD: D9UZ5Q
 Compound Name Vorolanib Phase 2 [37]
Synonyms
UNII-YP8G3I74EL; YP8G3I74EL; 1013920-15-4; (S,Z)-N-(1-(Dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide; Vorolanib [INN]; SCHEMBL2439528; CHEMBL4297587; N-((3S)-1-(dimethylcarbamoyl)pyrrolidin-3-yl)-5-((Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide; s6843; DB15247; HY-109019; CS-0030517; Q27294638; 1H-Pyrrole-3-carboxamide, N-((3S)-1-((dimethylamino)carbonyl)-3-pyrrolidinyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-
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CID: 59215954
TTD: D8AG3S
DrugBank: DB15247
 Compound Name Xofigo Phase 2 [38]
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TTD: D6B7FP
 Compound Name Bintrafusp alfa Phase 2 [39]
External Link
TTD: D5J3BL
 Compound Name Voyager-V1 Phase 2 [40]
Synonyms
VSV-IFNBeta-NIS
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TTD: D4AGB6
 Compound Name AB-106 Phase 2 [41]
Synonyms
DS6051b; GTPL11198; AB106
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CID: 154699459
TTD: D2KV8B
 Compound Name RO-5126766 Phase 2 [42]
Synonyms
VS-6766; CH-5126766; Dual Raf/MEK protein kinase inhibitor (cancer), Roche
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CID: 16719221
TTD: D0M6BD
DrugBank: DB15254
 Compound Name TC-210 Phase 1/2 [43]
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TTD: DX6O9V
 Compound Name EMB-01 Phase 1/2 [44]
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TTD: DWQ6J1
 Compound Name NM21-1480 Phase 1/2 [45]
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TTD: DUVH60
 Compound Name MRx0518 Phase 1/2 [46]
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TTD: DP4J2K
 Compound Name DZD9008 Phase 1/2 [47]
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TTD: DM8Y2N
 Compound Name BGB-A425 Phase 1/2 [48]
External Link
TTD: D7UIZ1
 Compound Name Rilvegostomig Phase 1/2 [49]
Synonyms
AZD2936
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TTD: D4RMC9
 Compound Name IK-007 Phase 1/2 [50]
Synonyms
grapiprant
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TTD: D1KES8
 Compound Name IBI318 Phase 1 [51]
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TTD: DX30BA
 Compound Name GEN-011 Phase 1 [52]
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TTD: DR1YQ7
 Compound Name ENV-105 Phase 1 [53]
Synonyms
Carotuximab
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TTD: DQ8K3R
 Compound Name AMG 160 Phase 1 [54]
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TTD: DOY4E6
 Compound Name ADP-A2M10 Phase 1 [55]
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TTD: DM38KC
 Compound Name MEDI5752 Phase 1 [56]
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TTD: D7L1MP
 Compound Name PF-07104091 Phase 1 [57]
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TTD: D5TH2B
 Compound Name PF-06936308 Phase 1 [58]
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TTD: D2LUK7
 Compound Name GEM3PSCA Phase 1 [59]
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TTD: D1L7DE
 Compound Name PF-07257876 Phase 1 [60]
External Link
TTD: D1A7OP
 Compound Name Cosibelimab Phase 1 [61]
Synonyms
CK-301/TG-1501
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TTD: D17URP
 Compound Name Gemcitabine Approved [62]
External Link
CID: 60750
TTD: D0AJ3K
DrugBank: DB00441
 Compound Name SMI-4a Investigative [63]
Synonyms
438190-29-5; SMI 4a; TCS PIM-1 4a; (Z)-SMI-4a; (Z)-5-(3-(trifluoromethyl)benzylidene)thiazolidine-2,4-dione; (5Z)-5-[3-(trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione; CHEMBL183906; (5Z)-5-[[3-(TRIFLUOROMETHYL)PHENYL]METHYLENE]-2,4-THIAZOLIDINEDIONE; (5Z)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione; 327033-36-3; C11H6F3NO2S; (Z)-5-(3-(Trifluoromethyl)benzylidene)-thiazolidine-2,4-dione; (5Z)-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione; Pim inhibitor 4a; 3vc4; SMI-4q; TCS PIM-1-4a; 5-(3-(Trifluoromethyl)benzylidene)thiazolidine-2,4-dione; 5-[3-(Trifluoromethyl)benzylidene]thiazolidine-2,4-dione; cc-717; thiazolidine-2,4-dione, 4a; SCHEMBL2541382; SCHEMBL2541388; BDBM26626; AOB6260; EX-A111; SYN1113; BDBM138364; HMS3229J21; 2720AH; HY-16576A; MFCD01152003; s8005; ZINC12576047; AKOS001314163; SMI-4a, >=98% (HPLC); CCG-265027; NCGC00345836-02; NCGC00345836-14; AC-32861; HY-15474; AB0165836; EC-000.2291; J3.561.866J; A11945; W-5256; US8877795, 12; Q27451064; 5-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
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CID: 1361334
TTD: DAJ3D2
References
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