m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00340)

Target Name	Transcriptional activator Myb (MYB)
Synonyms	Proto-oncogene c-Myb Click to Show/Hide
Gene Name	MYB
Chromosomal Location	6q23.3
Function	Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. Click to Show/Hide
Gene ID	4602
Uniprot ID	MYB_HUMAN
HGNC ID	HGNC:7545
KEGG ID	hsa:4602

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

MYB can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 14 (METTL14) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL14*
Cell Line	MDA-MB-231	Homo sapiens
Treatment: siMETTL14 MDA-MB-231 cells Control: MDA-MB-231 cells		GSE81164
Regulation		logFC: 9.21E-01 p-value: 4.44E-04
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	METTL14 in normal myelopoiesis and AML pathogenesis, as featured by blocking myeloid differentiation and promoting self-renewal of normal HSPCs and LSCs/LICs. METTL14 exerts its oncogenic role by regulating its mRNA targets (e.g., Transcriptional activator Myb (MYB) and MYC) through m6A modification, while the protein itself is negatively regulated by SPI1.
Target Regulation	Up regulation
Responsed Disease	Acute myeloid leukaemia		ICD-11: 2A60	Disease Info
Cell Process	Cell survival/proliferation
In-vitro Model	HEK293T	Normal	Homo sapiens	CVCL_0063
	HSPC (Human hematopoietic stem cell)
	MNC (Cord blood pluripotent stem cells)
	OP9	Normal	Mus musculus	CVCL_4398
	U-937	Adult acute monocytic leukemia	Homo sapiens	CVCL_0007
In-vivo Model	Lin^- HSPCs were purified from BM of wildtype mice and 0.1×10⁶ cells were seeded in 2 mL OP9 medium onto the OP9 cells with the addition of 10 ng/mL mouse IL-3, 10 ng/mL human IL-6, 10 ng/mL mouse IL-7, 10 ng/mL mouse Flt-3L, and 50 ng/mL mouse stem cell factor (SCF).

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) [READER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[2]
Response Summary	IGF2BP1 decreases leukemia cells' tumorigenicity, promotes myeloid differentiation, increases leukemia cell death, and sensitizes acute myeloid leukemia cells to chemotherapeutic drugs. IGF2BP1 affects proliferation and tumorigenic potential of leukemia cells through critical regulators of self-renewal HOXB4 and Transcriptional activator Myb (MYB) and through regulation of expression of the aldehyde dehydrogenase, ALDH1A1.
Target Regulation	Up regulation
Responsed Disease	Acute myeloid leukaemia		ICD-11: 2A60	Disease Info
In-vitro Model	MOLT-16	T acute lymphoblastic leukemia	Homo sapiens	CVCL_1424
	Reh	B acute lymphoblastic leukemia	Homo sapiens	CVCL_1650
	SKNO-1	Myeloid leukemia with maturation	Homo sapiens	CVCL_2196
	Tanoue	B acute lymphoblastic leukemia	Homo sapiens	CVCL_1852
In-vivo Model	For the engraftment experiments, 1×10³ 1×10⁶ cells were injected into tail veins of non-irradiated 6-10 week-old female mice in 100 uL of DPBS per mouse. No blinding or randomization was applied to mice experiments. Routinely, each in vivo experiment was performed with three technical replicates (three mice per group) and independently repeated two to three times for each cell line.

Acute myeloid leukaemia [ICD-11: 2A60]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[2]
Response Summary	IGF2BP1 decreases leukemia cells' tumorigenicity, promotes myeloid differentiation, increases leukemia cell death, and sensitizes acute myeloid leukemia cells to chemotherapeutic drugs. IGF2BP1 affects proliferation and tumorigenic potential of leukemia cells through critical regulators of self-renewal HOXB4 and Transcriptional activator Myb (MYB) and through regulation of expression of the aldehyde dehydrogenase, ALDH1A1.
Responsed Disease	Acute myeloid leukaemia [ICD-11: 2A60]
Target Regulator	Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)		READER	Regulator Info
Target Regulation	Up regulation
In-vitro Model	MOLT-16	T acute lymphoblastic leukemia	Homo sapiens	CVCL_1424
	Reh	B acute lymphoblastic leukemia	Homo sapiens	CVCL_1650
	SKNO-1	Myeloid leukemia with maturation	Homo sapiens	CVCL_2196
	Tanoue	B acute lymphoblastic leukemia	Homo sapiens	CVCL_1852
In-vivo Model	For the engraftment experiments, 1×10³ 1×10⁶ cells were injected into tail veins of non-irradiated 6-10 week-old female mice in 100 uL of DPBS per mouse. No blinding or randomization was applied to mice experiments. Routinely, each in vivo experiment was performed with three technical replicates (three mice per group) and independently repeated two to three times for each cell line.
Experiment 2 Reporting the m6A-centered Disease Response				[1]
Response Summary	METTL14 in normal myelopoiesis and AML pathogenesis, as featured by blocking myeloid differentiation and promoting self-renewal of normal HSPCs and LSCs/LICs. METTL14 exerts its oncogenic role by regulating its mRNA targets (e.g., Transcriptional activator Myb (MYB) and MYC) through m6A modification, while the protein itself is negatively regulated by SPI1.
Responsed Disease	Acute myeloid leukaemia [ICD-11: 2A60]
Target Regulator	Methyltransferase-like 14 (METTL14)		WRITER	Regulator Info
Target Regulation	Up regulation
Cell Process	Cell survival/proliferation
In-vitro Model	HEK293T	Normal	Homo sapiens	CVCL_0063
	HSPC (Human hematopoietic stem cell)
	MNC (Cord blood pluripotent stem cells)
	OP9	Normal	Mus musculus	CVCL_4398
	U-937	Adult acute monocytic leukemia	Homo sapiens	CVCL_0007
In-vivo Model	Lin^- HSPCs were purified from BM of wildtype mice and 0.1×10⁶ cells were seeded in 2 mL OP9 medium onto the OP9 cells with the addition of 10 ng/mL mouse IL-3, 10 ng/mL human IL-6, 10 ng/mL mouse IL-7, 10 ng/mL mouse Flt-3L, and 50 ng/mL mouse stem cell factor (SCF).

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00340)

Transcriptional activator Myb (MYB)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE001715		Click to Show/Hide the Full List
mod site	chr6:135207624-135207625:+		[3]
Sequence	TTAAAATTAGAAATGCCGAGAAGCTATGTGTTTGACATTTT
Transcript ID List	ENST00000367814.8; ENST00000526565.5; ENST00000528343.5; ENST00000526320.5; ENST00000531634.5; ENST00000341911.10; ENST00000528015.5; ENST00000442647.7; ENST00000533808.5; ENST00000524588.5; ENST00000533624.5; ENST00000525002.5; ENST00000525477.5; ENST00000525369.5; ENST00000525514.5; ENST00000438901.6; ENST00000529586.5; ENST00000533384.5; ENST00000531845.5; ENST00000526889.5; ENST00000531737.5; ENST00000525940.5; ENST00000616088.4; ENST00000463282.6; ENST00000339290.9; ENST00000316528.12; ENST00000528774.5; ENST00000618728.4; ENST00000531519.5; ENST00000533837.5; ENST00000534044.5; ENST00000528140.5; ENST00000526187.5; ENST00000534121.5; ENST00000528345.5; ENST00000529262.5; ENST00000367812.6
External Link	RMBase: RNA-editing_site_118979

N6-methyladenosine (m6A)

In total 43 m6A sequence/site(s) in this target gene
mod ID: M6ASITE077181		Click to Show/Hide the Full List
mod site	chr6:135181385-135181386:+		[4]
Sequence	CCTCCTCTTTCTCCTGAGAAACTTCGCCCCAGCGGTGCGGA
Motif Score	2.627720238
Cell/Tissue List	Jurkat; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000533837.5; ENST00000527615.5; ENST00000442647.7; ENST00000616088.4; ENST00000618728.4; ENST00000316528.12; ENST00000367812.6; ENST00000463282.6; ENST00000341911.10; ENST00000525477.5; ENST00000339290.9; ENST00000367814.8
External Link	RMBase: m6A_site_734752
mod ID: M6ASITE077182		Click to Show/Hide the Full List
mod site	chr6:135181524-135181525:+		[5]
Sequence	CGCCGCGCCATGGCCCGAAGACCCCGGCACAGGTAACGGGG
Motif Score	2.876744048
Cell/Tissue List	CD34; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000339290.9; ENST00000528140.5; ENST00000529262.5; ENST00000526187.5; ENST00000529586.5; ENST00000367812.6; ENST00000525002.5; ENST00000533384.5; ENST00000525940.5; ENST00000442647.7; ENST00000316528.12; ENST00000531634.5; ENST00000524588.5; ENST00000528015.5; ENST00000534044.5; ENST00000528774.5; ENST00000463282.6; ENST00000420123.6; ENST00000525477.5; ENST00000533624.5; ENST00000618728.4; ENST00000367814.8; ENST00000438901.6; ENST00000531519.5; ENST00000531737.5; ENST00000525369.5; ENST00000528345.5; ENST00000527615.5; ENST00000526565.5; ENST00000525514.5; ENST00000526320.5; ENST00000533808.5; ENST00000533837.5; ENST00000528343.5; ENST00000534121.5; ENST00000526889.5; ENST00000341911.10; ENST00000616088.4
External Link	RMBase: m6A_site_734753
mod ID: M6ASITE077183		Click to Show/Hide the Full List
mod site	chr6:135185931-135185932:+		[5]
Sequence	CAGTGACGAGGATGATGAGGACTTTGAGATGTGTGACCATG
Motif Score	4.065041667
Cell/Tissue List	CD34; MT4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000526889.5; ENST00000367812.6; ENST00000525477.5; ENST00000463282.6; ENST00000339290.9; ENST00000524588.5; ENST00000529586.5; ENST00000533384.5; ENST00000529262.5; ENST00000526320.5; ENST00000420123.6; ENST00000618728.4; ENST00000533808.5; ENST00000528774.5; ENST00000531634.5; ENST00000533624.5; ENST00000525002.5; ENST00000525514.5; ENST00000438901.6; ENST00000531737.5; ENST00000528015.5; ENST00000616088.4; ENST00000367814.8; ENST00000533837.5; ENST00000525940.5; ENST00000341911.10; ENST00000525369.5; ENST00000527615.5; ENST00000442647.7; ENST00000316528.12; ENST00000526187.5; ENST00000534044.5; ENST00000531519.5; ENST00000528140.5; ENST00000526565.5; ENST00000531845.5; ENST00000528345.5; ENST00000528343.5; ENST00000534121.5
External Link	RMBase: m6A_site_734754
mod ID: M6ASITE077184		Click to Show/Hide the Full List
mod site	chr6:135185999-135186000:+		[6]
Sequence	GAAAGCGTCACTTGGGGAAAACAAGGTGGACCCGGGAAGAG
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; MT4; MM6; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000525002.5; ENST00000524588.5; ENST00000341911.10; ENST00000526320.5; ENST00000528140.5; ENST00000525514.5; ENST00000420123.6; ENST00000531845.5; ENST00000529262.5; ENST00000533384.5; ENST00000463282.6; ENST00000616088.4; ENST00000618728.4; ENST00000528774.5; ENST00000531519.5; ENST00000525477.5; ENST00000367812.6; ENST00000526187.5; ENST00000534121.5; ENST00000526889.5; ENST00000528345.5; ENST00000525940.5; ENST00000316528.12; ENST00000531737.5; ENST00000533624.5; ENST00000528015.5; ENST00000531634.5; ENST00000527615.5; ENST00000367814.8; ENST00000339290.9; ENST00000533808.5; ENST00000438901.6; ENST00000533837.5; ENST00000526565.5; ENST00000528343.5; ENST00000525369.5; ENST00000442647.7; ENST00000529586.5; ENST00000534044.5
External Link	RMBase: m6A_site_734755
mod ID: M6ASITE077185		Click to Show/Hide the Full List
mod site	chr6:135186008-135186009:+		[6]
Sequence	ACTTGGGGAAAACAAGGTGGACCCGGGAAGAGGTAACTAAT
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; MM6; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000534044.5; ENST00000528343.5; ENST00000528140.5; ENST00000525477.5; ENST00000616088.4; ENST00000438901.6; ENST00000533384.5; ENST00000533837.5; ENST00000528015.5; ENST00000531519.5; ENST00000525514.5; ENST00000529586.5; ENST00000316528.12; ENST00000618728.4; ENST00000529262.5; ENST00000531737.5; ENST00000367812.6; ENST00000534121.5; ENST00000527615.5; ENST00000367814.8; ENST00000525940.5; ENST00000420123.6; ENST00000528345.5; ENST00000533624.5; ENST00000341911.10; ENST00000531634.5; ENST00000526320.5; ENST00000526565.5; ENST00000339290.9; ENST00000463282.6; ENST00000531845.5; ENST00000442647.7; ENST00000525002.5; ENST00000528774.5; ENST00000526889.5; ENST00000524588.5; ENST00000526187.5; ENST00000533808.5; ENST00000525369.5
External Link	RMBase: m6A_site_734756
mod ID: M6ASITE077186		Click to Show/Hide the Full List
mod site	chr6:135187841-135187842:+		[6]
Sequence	TAAATGTCTTAGGATGAAAAACTGAAGAAGCTGGTGGAACA
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; MM6; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000339290.9; ENST00000526565.5; ENST00000528343.5; ENST00000616088.4; ENST00000525514.5; ENST00000316528.12; ENST00000526889.5; ENST00000533384.5; ENST00000525002.5; ENST00000525369.5; ENST00000438901.6; ENST00000525477.5; ENST00000528015.5; ENST00000531634.5; ENST00000533837.5; ENST00000430686.2; ENST00000534044.5; ENST00000525940.5; ENST00000528345.5; ENST00000618728.4; ENST00000367814.8; ENST00000534121.5; ENST00000524588.5; ENST00000442647.7; ENST00000533808.5; ENST00000531519.5; ENST00000528774.5; ENST00000341911.10; ENST00000529262.5; ENST00000367812.6; ENST00000463282.6; ENST00000527615.5; ENST00000420123.6; ENST00000533624.5; ENST00000526320.5; ENST00000529586.5; ENST00000526187.5; ENST00000531845.5; ENST00000531737.5; ENST00000528140.5
External Link	RMBase: m6A_site_734757
mod ID: M6ASITE077187		Click to Show/Hide the Full List
mod site	chr6:135187859-135187860:+		[6]
Sequence	AAACTGAAGAAGCTGGTGGAACAGAATGGAACAGATGACTG
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; MM6; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000526187.5; ENST00000442647.7; ENST00000531737.5; ENST00000525369.5; ENST00000533808.5; ENST00000528015.5; ENST00000339290.9; ENST00000316528.12; ENST00000526889.5; ENST00000533624.5; ENST00000528774.5; ENST00000463282.6; ENST00000438901.6; ENST00000534044.5; ENST00000533837.5; ENST00000533384.5; ENST00000531845.5; ENST00000341911.10; ENST00000367814.8; ENST00000525002.5; ENST00000616088.4; ENST00000367812.6; ENST00000529586.5; ENST00000534121.5; ENST00000420123.6; ENST00000527615.5; ENST00000524588.5; ENST00000430686.2; ENST00000528345.5; ENST00000526565.5; ENST00000525940.5; ENST00000531634.5; ENST00000525477.5; ENST00000531519.5; ENST00000526320.5; ENST00000529262.5; ENST00000528343.5; ENST00000525514.5; ENST00000618728.4; ENST00000528140.5
External Link	RMBase: m6A_site_734758
mod ID: M6ASITE077188		Click to Show/Hide the Full List
mod site	chr6:135187869-135187870:+		[6]
Sequence	AGCTGGTGGAACAGAATGGAACAGATGACTGGAAAGTTATT
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; MM6; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000528015.5; ENST00000533624.5; ENST00000420123.6; ENST00000367812.6; ENST00000531519.5; ENST00000534121.5; ENST00000529262.5; ENST00000316528.12; ENST00000528343.5; ENST00000527615.5; ENST00000528774.5; ENST00000528345.5; ENST00000525514.5; ENST00000526187.5; ENST00000438901.6; ENST00000531737.5; ENST00000533384.5; ENST00000341911.10; ENST00000533837.5; ENST00000525369.5; ENST00000533808.5; ENST00000463282.6; ENST00000534044.5; ENST00000618728.4; ENST00000525477.5; ENST00000531634.5; ENST00000529586.5; ENST00000525940.5; ENST00000430686.2; ENST00000526889.5; ENST00000616088.4; ENST00000526320.5; ENST00000528140.5; ENST00000531845.5; ENST00000526565.5; ENST00000442647.7; ENST00000525002.5; ENST00000339290.9; ENST00000524588.5; ENST00000367814.8
External Link	RMBase: m6A_site_734759
mod ID: M6ASITE077189		Click to Show/Hide the Full List
mod site	chr6:135189796-135189797:+		[6]
Sequence	CTTTATTTGTCTAGAATCGAACAGATGTGCAGTGCCAGCAC
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000525369.5; ENST00000531634.5; ENST00000528774.5; ENST00000533624.5; ENST00000316528.12; ENST00000526565.5; ENST00000367812.6; ENST00000527615.5; ENST00000528343.5; ENST00000534044.5; ENST00000339290.9; ENST00000528015.5; ENST00000534121.5; ENST00000531737.5; ENST00000525940.5; ENST00000618728.4; ENST00000526187.5; ENST00000528140.5; ENST00000430686.2; ENST00000531519.5; ENST00000528345.5; ENST00000526889.5; ENST00000533808.5; ENST00000533384.5; ENST00000463282.6; ENST00000616088.4; ENST00000525002.5; ENST00000524588.5; ENST00000367814.8; ENST00000341911.10; ENST00000529586.5; ENST00000526320.5; ENST00000531845.5; ENST00000529262.5; ENST00000533837.5; ENST00000442647.7; ENST00000420123.6; ENST00000438901.6; ENST00000525477.5; ENST00000525514.5
External Link	RMBase: m6A_site_734760
mod ID: M6ASITE077190		Click to Show/Hide the Full List
mod site	chr6:135189836-135189837:+		[6]
Sequence	CCGATGGCAGAAAGTACTAAACCCTGAGCTCATCAAGGGTC
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000533624.5; ENST00000524588.5; ENST00000341911.10; ENST00000527615.5; ENST00000526320.5; ENST00000616088.4; ENST00000526565.5; ENST00000525514.5; ENST00000430686.2; ENST00000531737.5; ENST00000529586.5; ENST00000526889.5; ENST00000442647.7; ENST00000526187.5; ENST00000534044.5; ENST00000463282.6; ENST00000367814.8; ENST00000316528.12; ENST00000528774.5; ENST00000528015.5; ENST00000525369.5; ENST00000525002.5; ENST00000528345.5; ENST00000531519.5; ENST00000420123.6; ENST00000339290.9; ENST00000533384.5; ENST00000528140.5; ENST00000534121.5; ENST00000533808.5; ENST00000531845.5; ENST00000525477.5; ENST00000438901.6; ENST00000533837.5; ENST00000528343.5; ENST00000618728.4; ENST00000367812.6; ENST00000525940.5; ENST00000531634.5; ENST00000529262.5
External Link	RMBase: m6A_site_734761
mod ID: M6ASITE077191		Click to Show/Hide the Full List
mod site	chr6:135189862-135189863:+		[6]
Sequence	AGCTCATCAAGGGTCCTTGGACCAAAGAAGAAGATCAGAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000528345.5; ENST00000341911.10; ENST00000616088.4; ENST00000528140.5; ENST00000525002.5; ENST00000527615.5; ENST00000531519.5; ENST00000528343.5; ENST00000524588.5; ENST00000534121.5; ENST00000438901.6; ENST00000367814.8; ENST00000420123.6; ENST00000525477.5; ENST00000531845.5; ENST00000526565.5; ENST00000531737.5; ENST00000618728.4; ENST00000526320.5; ENST00000533384.5; ENST00000526889.5; ENST00000442647.7; ENST00000528015.5; ENST00000529586.5; ENST00000526187.5; ENST00000533808.5; ENST00000430686.2; ENST00000533624.5; ENST00000463282.6; ENST00000525940.5; ENST00000533837.5; ENST00000525369.5; ENST00000534044.5; ENST00000367812.6; ENST00000525514.5; ENST00000529262.5; ENST00000528774.5; ENST00000316528.12; ENST00000531634.5; ENST00000339290.9
External Link	RMBase: m6A_site_734762
mod ID: M6ASITE077192		Click to Show/Hide the Full List
mod site	chr6:135190203-135190204:+		[6]
Sequence	TTAAAGGGGAGAATTGGAAAACAATGTAGGGAGAGGTGGCA
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000526187.5; ENST00000526320.5; ENST00000531634.5; ENST00000529262.5; ENST00000533808.5; ENST00000526565.5; ENST00000341911.10; ENST00000525940.5; ENST00000528015.5; ENST00000531737.5; ENST00000531845.5; ENST00000534121.5; ENST00000367812.6; ENST00000525002.5; ENST00000528774.5; ENST00000339290.9; ENST00000420123.6; ENST00000525477.5; ENST00000463282.6; ENST00000525514.5; ENST00000316528.12; ENST00000531519.5; ENST00000533837.5; ENST00000524588.5; ENST00000533624.5; ENST00000438901.6; ENST00000534044.5; ENST00000533384.5; ENST00000528343.5; ENST00000526889.5; ENST00000527615.5; ENST00000528345.5; ENST00000528140.5; ENST00000616088.4; ENST00000367814.8; ENST00000618728.4; ENST00000525369.5; ENST00000529586.5; ENST00000430686.2; ENST00000442647.7
External Link	RMBase: m6A_site_734763
mod ID: M6ASITE077193		Click to Show/Hide the Full List
mod site	chr6:135190252-135190253:+		[6]
Sequence	TGAATCCAGAAGTTAAGAAAACCTCCTGGACAGAAGAGGAA
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000463282.6; ENST00000526889.5; ENST00000534121.5; ENST00000438901.6; ENST00000528345.5; ENST00000341911.10; ENST00000618728.4; ENST00000533624.5; ENST00000442647.7; ENST00000528140.5; ENST00000529586.5; ENST00000526565.5; ENST00000528343.5; ENST00000534044.5; ENST00000420123.6; ENST00000430686.2; ENST00000533837.5; ENST00000339290.9; ENST00000531845.5; ENST00000528015.5; ENST00000524588.5; ENST00000525477.5; ENST00000525369.5; ENST00000316528.12; ENST00000533384.5; ENST00000533808.5; ENST00000528774.5; ENST00000529262.5; ENST00000531634.5; ENST00000616088.4; ENST00000527615.5; ENST00000531519.5; ENST00000526320.5; ENST00000367814.8; ENST00000526187.5; ENST00000525002.5; ENST00000531737.5; ENST00000525514.5; ENST00000525940.5; ENST00000367812.6
External Link	RMBase: m6A_site_734764
mod ID: M6ASITE077194		Click to Show/Hide the Full List
mod site	chr6:135190261-135190262:+		[6]
Sequence	AAGTTAAGAAAACCTCCTGGACAGAAGAGGAAGACAGAATT
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000430686.2; ENST00000531737.5; ENST00000524588.5; ENST00000438901.6; ENST00000528345.5; ENST00000529262.5; ENST00000367812.6; ENST00000533808.5; ENST00000341911.10; ENST00000528343.5; ENST00000525514.5; ENST00000533384.5; ENST00000463282.6; ENST00000529586.5; ENST00000534121.5; ENST00000339290.9; ENST00000442647.7; ENST00000533624.5; ENST00000525477.5; ENST00000531845.5; ENST00000420123.6; ENST00000316528.12; ENST00000616088.4; ENST00000525369.5; ENST00000526187.5; ENST00000618728.4; ENST00000531519.5; ENST00000531634.5; ENST00000527615.5; ENST00000526320.5; ENST00000534044.5; ENST00000528140.5; ENST00000526565.5; ENST00000367814.8; ENST00000525002.5; ENST00000526889.5; ENST00000533837.5; ENST00000528015.5; ENST00000528774.5; ENST00000525940.5
External Link	RMBase: m6A_site_734765
mod ID: M6ASITE077195		Click to Show/Hide the Full List
mod site	chr6:135190274-135190275:+		[6]
Sequence	CTCCTGGACAGAAGAGGAAGACAGAATTATTTACCAGGCAC
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000367812.6; ENST00000525514.5; ENST00000533384.5; ENST00000525477.5; ENST00000525369.5; ENST00000534044.5; ENST00000528774.5; ENST00000616088.4; ENST00000438901.6; ENST00000526565.5; ENST00000531845.5; ENST00000618728.4; ENST00000524588.5; ENST00000534121.5; ENST00000316528.12; ENST00000533837.5; ENST00000533808.5; ENST00000529586.5; ENST00000526889.5; ENST00000430686.2; ENST00000463282.6; ENST00000526187.5; ENST00000525940.5; ENST00000529262.5; ENST00000526320.5; ENST00000341911.10; ENST00000527615.5; ENST00000339290.9; ENST00000528343.5; ENST00000525002.5; ENST00000367814.8; ENST00000528345.5; ENST00000531519.5; ENST00000528015.5; ENST00000531737.5; ENST00000533624.5; ENST00000420123.6; ENST00000528140.5; ENST00000442647.7; ENST00000531634.5
External Link	RMBase: m6A_site_734766
mod ID: M6ASITE077196		Click to Show/Hide the Full List
mod site	chr6:135190302-135190303:+		[6]
Sequence	ATTTACCAGGCACACAAGAGACTGGGGAACAGATGGGCAGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000533837.5; ENST00000367814.8; ENST00000531737.5; ENST00000534121.5; ENST00000531634.5; ENST00000430686.2; ENST00000529262.5; ENST00000524588.5; ENST00000526565.5; ENST00000525514.5; ENST00000528774.5; ENST00000528343.5; ENST00000525940.5; ENST00000533384.5; ENST00000525477.5; ENST00000442647.7; ENST00000529586.5; ENST00000616088.4; ENST00000525369.5; ENST00000534044.5; ENST00000528140.5; ENST00000531845.5; ENST00000526889.5; ENST00000526320.5; ENST00000526187.5; ENST00000528345.5; ENST00000420123.6; ENST00000525002.5; ENST00000339290.9; ENST00000618728.4; ENST00000367812.6; ENST00000531519.5; ENST00000527615.5; ENST00000533808.5; ENST00000438901.6; ENST00000316528.12; ENST00000463282.6; ENST00000533624.5; ENST00000341911.10; ENST00000528015.5
External Link	RMBase: m6A_site_734767
mod ID: M6ASITE077197		Click to Show/Hide the Full List
mod site	chr6:135190310-135190311:+		[6]
Sequence	GGCACACAAGAGACTGGGGAACAGATGGGCAGAAATCGCAA
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000533624.5; ENST00000525002.5; ENST00000525940.5; ENST00000528343.5; ENST00000526320.5; ENST00000420123.6; ENST00000618728.4; ENST00000524588.5; ENST00000442647.7; ENST00000527615.5; ENST00000341911.10; ENST00000531845.5; ENST00000438901.6; ENST00000531737.5; ENST00000463282.6; ENST00000525514.5; ENST00000525369.5; ENST00000534121.5; ENST00000531519.5; ENST00000367812.6; ENST00000529262.5; ENST00000526889.5; ENST00000367814.8; ENST00000534044.5; ENST00000533837.5; ENST00000616088.4; ENST00000339290.9; ENST00000430686.2; ENST00000316528.12; ENST00000529586.5; ENST00000528774.5; ENST00000526187.5; ENST00000525477.5; ENST00000533808.5; ENST00000533384.5; ENST00000531634.5; ENST00000526565.5; ENST00000528140.5; ENST00000528345.5; ENST00000528015.5
External Link	RMBase: m6A_site_734768
mod ID: M6ASITE077198		Click to Show/Hide the Full List
mod site	chr6:135194357-135194358:+		[5]
Sequence	CTTACTTTGTAATTTCAGAGACACTATAATGATGAAGACCC
Motif Score	2.897386905
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000525514.5; ENST00000525940.5; ENST00000531737.5; ENST00000526889.5; ENST00000616088.4; ENST00000526320.5; ENST00000533837.5; ENST00000533624.5; ENST00000420123.6; ENST00000442647.7; ENST00000531845.5; ENST00000438901.6; ENST00000430686.2; ENST00000529262.5; ENST00000526565.5; ENST00000533384.5; ENST00000528774.5; ENST00000529586.5; ENST00000527615.5; ENST00000367814.8; ENST00000528343.5; ENST00000534121.5; ENST00000533808.5; ENST00000528015.5; ENST00000534044.5; ENST00000525477.5; ENST00000339290.9; ENST00000526187.5; ENST00000528345.5; ENST00000618728.4; ENST00000316528.12; ENST00000531634.5; ENST00000367812.6; ENST00000463282.6; ENST00000341911.10; ENST00000525369.5; ENST00000525002.5; ENST00000524588.5; ENST00000528140.5; ENST00000531519.5
External Link	RMBase: m6A_site_734769
mod ID: M6ASITE077199		Click to Show/Hide the Full List
mod site	chr6:135194374-135194375:+		[6]
Sequence	GAGACACTATAATGATGAAGACCCTGAGAAGGAAAAGCGAA
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000528343.5; ENST00000526889.5; ENST00000463282.6; ENST00000531519.5; ENST00000533808.5; ENST00000339290.9; ENST00000527615.5; ENST00000526187.5; ENST00000316528.12; ENST00000616088.4; ENST00000528345.5; ENST00000534044.5; ENST00000525369.5; ENST00000341911.10; ENST00000442647.7; ENST00000529262.5; ENST00000533384.5; ENST00000525514.5; ENST00000525940.5; ENST00000367812.6; ENST00000528774.5; ENST00000525002.5; ENST00000528015.5; ENST00000531634.5; ENST00000531845.5; ENST00000524588.5; ENST00000526565.5; ENST00000526320.5; ENST00000420123.6; ENST00000367814.8; ENST00000525477.5; ENST00000618728.4; ENST00000531737.5; ENST00000534121.5; ENST00000438901.6; ENST00000528140.5; ENST00000533624.5; ENST00000430686.2; ENST00000533837.5; ENST00000529586.5
External Link	RMBase: m6A_site_734770
mod ID: M6ASITE077200		Click to Show/Hide the Full List
mod site	chr6:135194444-135194445:+		[6]
Sequence	ACCGAGAATGAGCTAAAAGGACAGCAGGTGCTACCAGTAAG
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; hESC-HEK293T; AML
Seq Type List	m6A-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000616088.4; ENST00000526565.5; ENST00000420123.6; ENST00000526889.5; ENST00000533808.5; ENST00000531519.5; ENST00000524588.5; ENST00000367814.8; ENST00000526320.5; ENST00000618728.4; ENST00000527615.5; ENST00000529262.5; ENST00000531845.5; ENST00000534044.5; ENST00000534121.5; ENST00000367812.6; ENST00000525940.5; ENST00000531737.5; ENST00000339290.9; ENST00000533837.5; ENST00000316528.12; ENST00000533384.5; ENST00000533624.5; ENST00000528140.5; ENST00000438901.6; ENST00000341911.10; ENST00000528343.5; ENST00000526187.5; ENST00000525369.5; ENST00000430686.2; ENST00000528345.5; ENST00000463282.6; ENST00000528015.5; ENST00000525514.5; ENST00000442647.7; ENST00000531634.5; ENST00000525477.5; ENST00000529586.5; ENST00000525002.5; ENST00000528774.5
External Link	RMBase: m6A_site_734771
mod ID: M6ASITE077201		Click to Show/Hide the Full List
mod site	chr6:135194465-135194466:+		[6]
Sequence	CAGCAGGTGCTACCAGTAAGACTGTCATCATGTGCTTGAAT
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000533837.5; ENST00000430686.2; ENST00000526187.5; ENST00000528140.5; ENST00000533624.5; ENST00000526320.5; ENST00000442647.7; ENST00000525002.5; ENST00000367814.8; ENST00000531737.5; ENST00000528343.5; ENST00000367812.6; ENST00000341911.10; ENST00000616088.4; ENST00000524588.5; ENST00000618728.4; ENST00000528345.5; ENST00000316528.12; ENST00000531519.5; ENST00000463282.6; ENST00000529262.5; ENST00000531845.5; ENST00000533384.5; ENST00000526565.5; ENST00000525369.5; ENST00000527615.5; ENST00000534121.5; ENST00000528015.5; ENST00000529586.5; ENST00000526889.5; ENST00000531634.5; ENST00000528774.5; ENST00000438901.6; ENST00000534044.5; ENST00000420123.6; ENST00000525477.5; ENST00000339290.9; ENST00000525514.5; ENST00000533808.5; ENST00000525940.5
External Link	RMBase: m6A_site_734772
mod ID: M6ASITE077202		Click to Show/Hide the Full List
mod site	chr6:135195809-135195810:+		[6]
Sequence	ACCATTGCCGACCACACCAGACCTCATGGAGACAGTGCACC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000528343.5; ENST00000367814.8; ENST00000526320.5; ENST00000525002.5; ENST00000528345.5; ENST00000533624.5; ENST00000529586.5; ENST00000534044.5; ENST00000528015.5; ENST00000533384.5; ENST00000442647.7; ENST00000533837.5; ENST00000531845.5; ENST00000528774.5; ENST00000531634.5; ENST00000534736.1; ENST00000526565.5; ENST00000526889.5; ENST00000367812.6; ENST00000316528.12; ENST00000528140.5; ENST00000524588.5; ENST00000341911.10; ENST00000527615.5; ENST00000529262.5; ENST00000534121.5; ENST00000531519.5; ENST00000526187.5; ENST00000618728.4; ENST00000339290.9; ENST00000438901.6; ENST00000525369.5; ENST00000463282.6; ENST00000616088.4; ENST00000525940.5; ENST00000533808.5; ENST00000525477.5; ENST00000525514.5; ENST00000531737.5
External Link	RMBase: m6A_site_734773
mod ID: M6ASITE077203		Click to Show/Hide the Full List
mod site	chr6:135195820-135195821:+		[6]
Sequence	CCACACCAGACCTCATGGAGACAGTGCACCTGTTTCCTGTT
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000533808.5; ENST00000525514.5; ENST00000463282.6; ENST00000529586.5; ENST00000528140.5; ENST00000442647.7; ENST00000529262.5; ENST00000526320.5; ENST00000525369.5; ENST00000528343.5; ENST00000316528.12; ENST00000531845.5; ENST00000527615.5; ENST00000533837.5; ENST00000534736.1; ENST00000531519.5; ENST00000367814.8; ENST00000525940.5; ENST00000526889.5; ENST00000341911.10; ENST00000528345.5; ENST00000616088.4; ENST00000528774.5; ENST00000438901.6; ENST00000534121.5; ENST00000533384.5; ENST00000526187.5; ENST00000531737.5; ENST00000533624.5; ENST00000618728.4; ENST00000525477.5; ENST00000531634.5; ENST00000526565.5; ENST00000528015.5; ENST00000524588.5; ENST00000367812.6; ENST00000339290.9; ENST00000525002.5; ENST00000534044.5
External Link	RMBase: m6A_site_734774
mod ID: M6ASITE077204		Click to Show/Hide the Full List
mod site	chr6:135195848-135195849:+		[6]
Sequence	CCTGTTTCCTGTTTGGGAGAACACCACTCCACTCCATCTCT
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000524588.5; ENST00000534121.5; ENST00000528343.5; ENST00000616088.4; ENST00000531634.5; ENST00000534044.5; ENST00000339290.9; ENST00000341911.10; ENST00000526889.5; ENST00000438901.6; ENST00000531737.5; ENST00000534736.1; ENST00000529586.5; ENST00000442647.7; ENST00000528140.5; ENST00000527615.5; ENST00000618728.4; ENST00000463282.6; ENST00000316528.12; ENST00000533624.5; ENST00000367812.6; ENST00000531519.5; ENST00000526187.5; ENST00000525477.5; ENST00000525514.5; ENST00000529262.5; ENST00000528015.5; ENST00000533837.5; ENST00000533384.5; ENST00000526320.5; ENST00000525002.5; ENST00000525369.5; ENST00000528345.5; ENST00000528774.5; ENST00000525940.5; ENST00000526565.5; ENST00000367814.8; ENST00000533808.5; ENST00000531845.5
External Link	RMBase: m6A_site_734775
mod ID: M6ASITE077205		Click to Show/Hide the Full List
mod site	chr6:135197077-135197078:+		[7]
Sequence	AGCAAAGAGAGGGCAATGGGACTAAACCTGCAGGAGAACCT
Motif Score	4.065041667
Cell/Tissue List	MM6; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000367814.8; ENST00000525477.5; ENST00000526565.5; ENST00000528345.5; ENST00000525369.5; ENST00000367812.6; ENST00000616088.4; ENST00000442647.7; ENST00000526187.5; ENST00000534044.5; ENST00000528774.5; ENST00000525002.5; ENST00000528140.5; ENST00000527615.5; ENST00000531519.5; ENST00000316528.12; ENST00000341911.10; ENST00000529262.5; ENST00000463282.6; ENST00000528015.5; ENST00000524588.5; ENST00000529586.5; ENST00000618728.4; ENST00000533808.5; ENST00000525940.5; ENST00000525514.5; ENST00000339290.9; ENST00000533384.5; ENST00000534736.1; ENST00000531845.5; ENST00000531634.5; ENST00000533837.5; ENST00000438901.6; ENST00000531737.5; ENST00000526320.5; ENST00000526889.5; ENST00000528343.5; ENST00000533624.5; ENST00000534121.5
External Link	RMBase: m6A_site_734776
mod ID: M6ASITE077206		Click to Show/Hide the Full List
mod site	chr6:135197082-135197083:+		[7]
Sequence	AGAGAGGGCAATGGGACTAAACCTGCAGGAGAACCTAGCCC
Motif Score	2.185083333
Cell/Tissue List	MM6; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000528140.5; ENST00000367812.6; ENST00000531519.5; ENST00000533624.5; ENST00000529262.5; ENST00000526565.5; ENST00000533837.5; ENST00000528343.5; ENST00000618728.4; ENST00000534736.1; ENST00000531737.5; ENST00000463282.6; ENST00000533808.5; ENST00000525369.5; ENST00000534044.5; ENST00000531845.5; ENST00000525477.5; ENST00000525940.5; ENST00000531634.5; ENST00000528774.5; ENST00000339290.9; ENST00000316528.12; ENST00000529586.5; ENST00000524588.5; ENST00000528015.5; ENST00000616088.4; ENST00000525002.5; ENST00000527615.5; ENST00000528345.5; ENST00000442647.7; ENST00000534121.5; ENST00000341911.10; ENST00000367814.8; ENST00000526187.5; ENST00000438901.6; ENST00000526889.5; ENST00000526320.5; ENST00000525514.5; ENST00000533384.5
External Link	RMBase: m6A_site_734777
mod ID: M6ASITE077207		Click to Show/Hide the Full List
mod site	chr6:135197094-135197095:+		[7]
Sequence	GGGACTAAACCTGCAGGAGAACCTAGCCCAAGGGTGAACAA
Motif Score	2.930744048
Cell/Tissue List	MM6; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000525940.5; ENST00000528343.5; ENST00000525369.5; ENST00000531519.5; ENST00000527615.5; ENST00000526187.5; ENST00000533624.5; ENST00000534121.5; ENST00000525514.5; ENST00000529262.5; ENST00000616088.4; ENST00000528015.5; ENST00000524588.5; ENST00000534736.1; ENST00000529586.5; ENST00000618728.4; ENST00000528140.5; ENST00000442647.7; ENST00000367812.6; ENST00000531737.5; ENST00000526320.5; ENST00000339290.9; ENST00000438901.6; ENST00000533384.5; ENST00000528774.5; ENST00000531845.5; ENST00000525477.5; ENST00000534044.5; ENST00000341911.10; ENST00000526889.5; ENST00000526565.5; ENST00000463282.6; ENST00000533808.5; ENST00000367814.8; ENST00000533837.5; ENST00000528345.5; ENST00000531634.5; ENST00000525002.5; ENST00000316528.12
External Link	RMBase: m6A_site_734778
mod ID: M6ASITE077208		Click to Show/Hide the Full List
mod site	chr6:135197111-135197112:+		[7]
Sequence	AGAACCTAGCCCAAGGGTGAACAAACGTATGTTGAGTGAGA
Motif Score	2.951386905
Cell/Tissue List	MM6; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000528343.5; ENST00000531634.5; ENST00000528774.5; ENST00000525369.5; ENST00000531845.5; ENST00000534044.5; ENST00000526187.5; ENST00000533384.5; ENST00000531519.5; ENST00000316528.12; ENST00000531737.5; ENST00000339290.9; ENST00000341911.10; ENST00000533837.5; ENST00000529586.5; ENST00000529262.5; ENST00000525002.5; ENST00000525477.5; ENST00000528015.5; ENST00000526889.5; ENST00000442647.7; ENST00000525940.5; ENST00000534736.1; ENST00000527615.5; ENST00000526320.5; ENST00000533624.5; ENST00000528345.5; ENST00000526565.5; ENST00000367812.6; ENST00000367814.8; ENST00000533808.5; ENST00000616088.4; ENST00000524588.5; ENST00000528140.5; ENST00000618728.4; ENST00000438901.6; ENST00000463282.6; ENST00000534121.5; ENST00000525514.5
External Link	RMBase: m6A_site_734779
mod ID: M6ASITE077209		Click to Show/Hide the Full List
mod site	chr6:135197237-135197238:+		[8]
Sequence	CAGCCCCTTAGCCACTGGAGACTGTAGCTCCTTCATATTTG
Motif Score	3.319380952
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000528015.5; ENST00000524588.5; ENST00000526889.5; ENST00000525002.5; ENST00000534044.5; ENST00000533837.5; ENST00000533384.5; ENST00000531737.5; ENST00000526187.5; ENST00000463282.6; ENST00000527615.5; ENST00000528345.5; ENST00000341911.10; ENST00000442647.7; ENST00000525369.5; ENST00000531845.5; ENST00000528343.5; ENST00000534121.5; ENST00000529262.5; ENST00000618728.4; ENST00000525514.5; ENST00000367814.8; ENST00000525940.5; ENST00000367812.6; ENST00000616088.4; ENST00000531634.5; ENST00000531519.5; ENST00000529586.5; ENST00000533808.5; ENST00000339290.9; ENST00000528774.5; ENST00000534736.1; ENST00000533624.5; ENST00000526320.5; ENST00000525477.5; ENST00000528140.5; ENST00000316528.12; ENST00000526565.5; ENST00000438901.6
External Link	RMBase: m6A_site_734780
mod ID: M6ASITE077210		Click to Show/Hide the Full List
mod site	chr6:135198914-135198915:+		[5]
Sequence	TCTCCATATTTAGTTCTTAAACACTTCCAGTAACCATGAAA
Motif Score	2.20572619
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000526565.5; ENST00000531845.5; ENST00000531634.5; ENST00000529586.5; ENST00000367812.6; ENST00000526187.5; ENST00000528345.5; ENST00000316528.12; ENST00000534121.5; ENST00000525514.5; ENST00000528140.5; ENST00000438901.6; ENST00000463282.6; ENST00000533624.5; ENST00000531519.5; ENST00000524588.5; ENST00000442647.7; ENST00000528015.5; ENST00000534044.5; ENST00000339290.9; ENST00000533837.5; ENST00000533808.5; ENST00000616088.4; ENST00000341911.10; ENST00000525002.5; ENST00000525477.5; ENST00000526320.5; ENST00000367814.8; ENST00000525369.5; ENST00000533384.5; ENST00000531737.5; ENST00000618728.4; ENST00000528343.5; ENST00000527615.5; ENST00000526889.5; ENST00000525940.5; ENST00000529262.5; ENST00000528774.5
External Link	RMBase: m6A_site_734781
mod ID: M6ASITE077211		Click to Show/Hide the Full List
mod site	chr6:135198935-135198936:+		[5]
Sequence	CACTTCCAGTAACCATGAAAACTCAGACTTGGAAATGCCTT
Motif Score	2.627720238
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000528345.5; ENST00000618728.4; ENST00000525514.5; ENST00000616088.4; ENST00000531845.5; ENST00000526889.5; ENST00000526565.5; ENST00000525002.5; ENST00000438901.6; ENST00000533808.5; ENST00000525477.5; ENST00000531737.5; ENST00000526320.5; ENST00000524588.5; ENST00000528140.5; ENST00000527615.5; ENST00000528343.5; ENST00000339290.9; ENST00000525369.5; ENST00000534121.5; ENST00000316528.12; ENST00000525940.5; ENST00000528015.5; ENST00000463282.6; ENST00000367812.6; ENST00000529586.5; ENST00000533837.5; ENST00000533384.5; ENST00000526187.5; ENST00000533624.5; ENST00000367814.8; ENST00000534044.5; ENST00000529262.5; ENST00000531519.5; ENST00000442647.7; ENST00000341911.10; ENST00000528774.5; ENST00000531634.5
External Link	RMBase: m6A_site_734782
mod ID: M6ASITE077212		Click to Show/Hide the Full List
mod site	chr6:135198941-135198942:+		[5]
Sequence	CAGTAACCATGAAAACTCAGACTTGGAAATGCCTTCTTTAA
Motif Score	3.319380952
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000367814.8; ENST00000533624.5; ENST00000531519.5; ENST00000526320.5; ENST00000528140.5; ENST00000525514.5; ENST00000339290.9; ENST00000341911.10; ENST00000367812.6; ENST00000438901.6; ENST00000529586.5; ENST00000524588.5; ENST00000528774.5; ENST00000531737.5; ENST00000527615.5; ENST00000618728.4; ENST00000531634.5; ENST00000531845.5; ENST00000525477.5; ENST00000528345.5; ENST00000526187.5; ENST00000533837.5; ENST00000525369.5; ENST00000526565.5; ENST00000316528.12; ENST00000534044.5; ENST00000442647.7; ENST00000533808.5; ENST00000525940.5; ENST00000525002.5; ENST00000528343.5; ENST00000533384.5; ENST00000534121.5; ENST00000529262.5; ENST00000528015.5; ENST00000616088.4; ENST00000463282.6; ENST00000526889.5
External Link	RMBase: m6A_site_734783
mod ID: M6ASITE077213		Click to Show/Hide the Full List
mod site	chr6:135199016-135199017:+		[5]
Sequence	TACAACACCATTTCATAGAGACCAGACTGTGAAAACTCAAA
Motif Score	2.876744048
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000529586.5; ENST00000525369.5; ENST00000528343.5; ENST00000339290.9; ENST00000463282.6; ENST00000533624.5; ENST00000316528.12; ENST00000528140.5; ENST00000525514.5; ENST00000341911.10; ENST00000525002.5; ENST00000528345.5; ENST00000526889.5; ENST00000526565.5; ENST00000531519.5; ENST00000525940.5; ENST00000534044.5; ENST00000526320.5; ENST00000367814.8; ENST00000531634.5; ENST00000528774.5; ENST00000533837.5; ENST00000528015.5; ENST00000525477.5; ENST00000616088.4; ENST00000438901.6; ENST00000526187.5; ENST00000527615.5; ENST00000367812.6; ENST00000531845.5; ENST00000531737.5; ENST00000534121.5; ENST00000529262.5; ENST00000533384.5; ENST00000524588.5; ENST00000442647.7; ENST00000618728.4; ENST00000533808.5
External Link	RMBase: m6A_site_734784
mod ID: M6ASITE077214		Click to Show/Hide the Full List
mod site	chr6:135199021-135199022:+		[5]
Sequence	CACCATTTCATAGAGACCAGACTGTGAAAACTCAAAAGGAA
Motif Score	3.319380952
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000463282.6; ENST00000528140.5; ENST00000533837.5; ENST00000525514.5; ENST00000526320.5; ENST00000533384.5; ENST00000339290.9; ENST00000531519.5; ENST00000531845.5; ENST00000525940.5; ENST00000531737.5; ENST00000316528.12; ENST00000525002.5; ENST00000526889.5; ENST00000442647.7; ENST00000525369.5; ENST00000438901.6; ENST00000618728.4; ENST00000526565.5; ENST00000367812.6; ENST00000341911.10; ENST00000367814.8; ENST00000534121.5; ENST00000527615.5; ENST00000531634.5; ENST00000528774.5; ENST00000533808.5; ENST00000533624.5; ENST00000528343.5; ENST00000524588.5; ENST00000528015.5; ENST00000526187.5; ENST00000529262.5; ENST00000616088.4; ENST00000534044.5; ENST00000525477.5; ENST00000528345.5; ENST00000529586.5
External Link	RMBase: m6A_site_734785
mod ID: M6ASITE077215		Click to Show/Hide the Full List
mod site	chr6:135199030-135199031:+		[5]
Sequence	ATAGAGACCAGACTGTGAAAACTCAAAAGGAAAATACTGTG
Motif Score	2.627720238
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000528015.5; ENST00000616088.4; ENST00000528345.5; ENST00000534044.5; ENST00000525477.5; ENST00000533624.5; ENST00000531845.5; ENST00000533837.5; ENST00000525002.5; ENST00000341911.10; ENST00000529586.5; ENST00000618728.4; ENST00000526187.5; ENST00000367814.8; ENST00000531737.5; ENST00000528774.5; ENST00000526320.5; ENST00000526565.5; ENST00000525514.5; ENST00000533808.5; ENST00000529262.5; ENST00000367812.6; ENST00000534121.5; ENST00000316528.12; ENST00000528343.5; ENST00000525940.5; ENST00000525369.5; ENST00000527615.5; ENST00000442647.7; ENST00000339290.9; ENST00000526889.5; ENST00000524588.5; ENST00000531634.5; ENST00000533384.5; ENST00000528140.5; ENST00000531519.5; ENST00000463282.6; ENST00000438901.6
External Link	RMBase: m6A_site_734786
mod ID: M6ASITE077216		Click to Show/Hide the Full List
mod site	chr6:135201666-135201667:+		[1]
Sequence	TCCAACTGATAAATCAGGAAACTTCTTCTGCTCACACCACT
Motif Score	2.627720238
Cell/Tissue List	NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000533624.5; ENST00000618728.4; ENST00000528345.5; ENST00000528015.5; ENST00000442647.7; ENST00000528774.5; ENST00000526565.5; ENST00000525940.5; ENST00000438901.6; ENST00000316528.12; ENST00000529262.5; ENST00000533384.5; ENST00000533808.5; ENST00000463282.6; ENST00000531634.5; ENST00000341911.10; ENST00000533837.5; ENST00000616088.4; ENST00000534044.5; ENST00000526320.5; ENST00000531519.5; ENST00000524588.5; ENST00000525477.5; ENST00000525002.5; ENST00000531737.5; ENST00000525514.5; ENST00000526889.5; ENST00000529586.5; ENST00000525369.5; ENST00000534121.5; ENST00000526187.5; ENST00000367814.8; ENST00000527615.5; ENST00000528140.5; ENST00000367812.6; ENST00000528343.5; ENST00000531845.5; ENST00000339290.9
External Link	RMBase: m6A_site_734787
mod ID: M6ASITE077217		Click to Show/Hide the Full List
mod site	chr6:135201696-135201697:+		[5]
Sequence	CTCACACCACTGGGAAGGGGACAGTCTGAATACCCAACTGT
Motif Score	3.643047619
Cell/Tissue List	CD34; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000531845.5; ENST00000533837.5; ENST00000463282.6; ENST00000529262.5; ENST00000528140.5; ENST00000534121.5; ENST00000529586.5; ENST00000367814.8; ENST00000525477.5; ENST00000527615.5; ENST00000616088.4; ENST00000316528.12; ENST00000531519.5; ENST00000438901.6; ENST00000525514.5; ENST00000533808.5; ENST00000526565.5; ENST00000533624.5; ENST00000341911.10; ENST00000525940.5; ENST00000528345.5; ENST00000531737.5; ENST00000525002.5; ENST00000524588.5; ENST00000525369.5; ENST00000528343.5; ENST00000533384.5; ENST00000534044.5; ENST00000526320.5; ENST00000442647.7; ENST00000528774.5; ENST00000526889.5; ENST00000367812.6; ENST00000526187.5; ENST00000528015.5; ENST00000618728.4; ENST00000339290.9; ENST00000531634.5
External Link	RMBase: m6A_site_734788
mod ID: M6ASITE077218		Click to Show/Hide the Full List
mod site	chr6:135201725-135201726:+		[5]
Sequence	ATACCCAACTGTTCACGCAGACCTCGCCTGTGGCAGATGCA
Motif Score	2.876744048
Cell/Tissue List	CD34; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000533624.5; ENST00000528774.5; ENST00000367814.8; ENST00000525514.5; ENST00000528140.5; ENST00000438901.6; ENST00000533837.5; ENST00000367812.6; ENST00000341911.10; ENST00000525940.5; ENST00000531519.5; ENST00000616088.4; ENST00000524588.5; ENST00000531634.5; ENST00000531737.5; ENST00000463282.6; ENST00000533808.5; ENST00000529262.5; ENST00000534121.5; ENST00000527615.5; ENST00000531845.5; ENST00000526320.5; ENST00000339290.9; ENST00000618728.4; ENST00000526565.5; ENST00000528015.5; ENST00000525477.5; ENST00000533384.5; ENST00000525002.5; ENST00000534044.5; ENST00000316528.12; ENST00000525369.5; ENST00000528343.5; ENST00000442647.7; ENST00000528345.5; ENST00000526187.5; ENST00000529586.5; ENST00000526889.5
External Link	RMBase: m6A_site_734789
mod ID: M6ASITE077219		Click to Show/Hide the Full List
mod site	chr6:135203265-135203266:+		[5]
Sequence	ACCAGCATCAGAAGATGAAGACAATGTTCTCAAAGCATTTA
Motif Score	2.897386905
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000316528.12; ENST00000367812.6; ENST00000341911.10; ENST00000533837.5; ENST00000463282.6; ENST00000616088.4; ENST00000533808.5; ENST00000529586.5; ENST00000533384.5; ENST00000531845.5; ENST00000525940.5; ENST00000529262.5; ENST00000442647.7; ENST00000525002.5; ENST00000367814.8; ENST00000525369.5; ENST00000529297.1; ENST00000531519.5; ENST00000526187.5; ENST00000524588.5; ENST00000533624.5; ENST00000618728.4; ENST00000526320.5; ENST00000528140.5; ENST00000525514.5; ENST00000528774.5; ENST00000438901.6; ENST00000528345.5; ENST00000534044.5; ENST00000525477.5; ENST00000339290.9; ENST00000527615.5; ENST00000531634.5; ENST00000526889.5; ENST00000534121.5; ENST00000528343.5; ENST00000526565.5; ENST00000531737.5; ENST00000528015.5
External Link	RMBase: m6A_site_734790
mod ID: M6ASITE077220		Click to Show/Hide the Full List
mod site	chr6:135203298-135203299:+		[5]
Sequence	AGCATTTACAGTACCTAAAAACAGGTCCCTGGCGAGCCCCT
Motif Score	2.20572619
Cell/Tissue List	CD34; hESC-HEK293T; AML
Seq Type List	m6A-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000529297.1; ENST00000531845.5; ENST00000531737.5; ENST00000534044.5; ENST00000531519.5; ENST00000533808.5; ENST00000528140.5; ENST00000616088.4; ENST00000525940.5; ENST00000442647.7; ENST00000525369.5; ENST00000528774.5; ENST00000438901.6; ENST00000533384.5; ENST00000529586.5; ENST00000533837.5; ENST00000528015.5; ENST00000341911.10; ENST00000367812.6; ENST00000529262.5; ENST00000526187.5; ENST00000533624.5; ENST00000316528.12; ENST00000527615.5; ENST00000526320.5; ENST00000525002.5; ENST00000525477.5; ENST00000463282.6; ENST00000525514.5; ENST00000526889.5; ENST00000534121.5; ENST00000339290.9; ENST00000531634.5; ENST00000526565.5; ENST00000618728.4; ENST00000367814.8; ENST00000528343.5; ENST00000524588.5; ENST00000528345.5
External Link	RMBase: m6A_site_734791
mod ID: M6ASITE077221		Click to Show/Hide the Full List
mod site	chr6:135218025-135218026:+		[9]
Sequence	TTTCAGAACACTTCAAGTTGACTTGGGATATATCATTCCTC
Motif Score	3.28175
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000533837.5; ENST00000339290.9; ENST00000341911.10; ENST00000438901.6; ENST00000531519.5; ENST00000442647.7; ENST00000367814.8; ENST00000618728.4; ENST00000367812.6; ENST00000316528.12; ENST00000533808.5; ENST00000525369.5; ENST00000526889.5; ENST00000531845.5; ENST00000525477.5; ENST00000463282.6; ENST00000526320.5; ENST00000616088.4; ENST00000529586.5; ENST00000525514.5
External Link	RMBase: m6A_site_734792
mod ID: M6ASITE077222		Click to Show/Hide the Full List
mod site	chr6:135218054-135218055:+		[9]
Sequence	ATATCATTCCTCAACATGAAACTTTTCATGAATGGGAGAAG
Motif Score	2.627720238
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000618728.4; ENST00000367814.8; ENST00000525514.5; ENST00000442647.7; ENST00000367812.6; ENST00000616088.4; ENST00000316528.12; ENST00000463282.6; ENST00000525477.5; ENST00000531845.5; ENST00000438901.6; ENST00000533808.5; ENST00000341911.10; ENST00000526889.5; ENST00000525369.5; ENST00000529586.5; ENST00000533837.5; ENST00000339290.9; ENST00000531519.5; ENST00000526320.5
External Link	RMBase: m6A_site_734793
mod ID: M6ASITE077223		Click to Show/Hide the Full List
mod site	chr6:135219004-135219005:+		[5]
Sequence	TCTAAGTGTATGGTCTCAGAACTGTTGCATGGATCCTGTGT
Motif Score	3.373380952
Cell/Tissue List	CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000367814.8; ENST00000463282.6; ENST00000525369.5; ENST00000339290.9; ENST00000525514.5; ENST00000533837.5; ENST00000525477.5; ENST00000341911.10; ENST00000616088.4; ENST00000531519.5; ENST00000442647.7; ENST00000526889.5; ENST00000529586.5; ENST00000533808.5; ENST00000316528.12; ENST00000526320.5; ENST00000367812.6; ENST00000438901.6; ENST00000531845.5; ENST00000618728.4
External Link	RMBase: m6A_site_734794

Ref 1	METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification. Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 10.1016/j.stem.2017.11.016. Epub 2017 Dec 28.
Ref 2	RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1. Leukemia. 2020 May;34(5):1354-1363. doi: 10.1038/s41375-019-0656-9. Epub 2019 Nov 25.
Ref 3	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 4	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Elife. 2016 Jul 2;5:e15528. doi: 10.7554/eLife.15528.
Ref 5	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 6	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 7	FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase. Cancer Cell. 2017 Jan 9;31(1):127-141. doi: 10.1016/j.ccell.2016.11.017. Epub 2016 Dec 22.
Ref 8	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 9	The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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