m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00045)
Target Name hsa-miR-320c
Synonyms
hsa_miR_320c
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Gene Name hsa-miR-320c
miRBase ID
MIMAT0005793
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
hsa-miR-320c can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) [READER]
 Regulator Info 
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary HNRNPC, YTHDF, ZC3H13, YTHDC2, and METTL14 were dysregulated in esophageal cancer tissues. miR-186 interacted with HNRNPC and suppressed the expression of HNRNPC. Four miRNAs (miR-186, hsa-miR-320c, miR-320d, and miR-320b) were used to construct a prognostic signature, which could serve as a prognostic predictor independent from routine clinicopathological features.
Responsed Disease Esophageal cancer ICD-11: 2B70
 Disease Info 
In-vitro Model HEEC cell line (Normal esophageal epithelial cell line)
KYSE-30 Esophageal squamous cell carcinoma Homo sapiens CVCL_1351
TE-1 Esophageal squamous cell carcinoma Homo sapiens CVCL_1759
Esophageal cancer [ICD-11: 2B70]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary HNRNPC, YTHDF, ZC3H13, YTHDC2, and METTL14 were dysregulated in esophageal cancer tissues. miR-186 interacted with HNRNPC and suppressed the expression of HNRNPC. Four miRNAs (miR-186, hsa-miR-320c, miR-320d, and miR-320b) were used to construct a prognostic signature, which could serve as a prognostic predictor independent from routine clinicopathological features.
Responsed Disease Esophageal cancer [ICD-11: 2B70]
Target Regulator Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) READER
 Regulator Info 
In-vitro Model HEEC cell line (Normal esophageal epithelial cell line)
KYSE-30 Esophageal squamous cell carcinoma Homo sapiens CVCL_1351
TE-1 Esophageal squamous cell carcinoma Homo sapiens CVCL_1759
References
Ref 1 Network analysis of miRNA targeting m6A-related genes in patients with esophageal cancer. PeerJ. 2021 Jul 29;9:e11893. doi: 10.7717/peerj.11893. eCollection 2021.