RNA-seq Results | M6AREG

Results indicating the target gene (PTEN ) expression regulated by m6A regulator (METTL14 )

2C12: Liver cancer

In total 1 results
Result 1 indicating the PTEN expression regulated by METTL14
Cell Line	HepG2 cell line		CVCL_0027
Condition	Hepatocellular carcinoma		Homo sapiens
Treatment: shMETTL14 HepG2 cells Control: shCtrl HepG2 cells			GSE121949
Regulation			logFC: -9.93E-01 p-value: 1.46E-04

Healthy

In total 2 results
Result 1 indicating the PTEN expression regulated by METTL14
Cell Line	BMDM
Condition	Healthy		Mus musculus
Treatment: METTL14 knockout mice BMDM Control: Wild type mice BMDM			GSE153512
Regulation			logFC: 1.05E+00 p-value: 7.22E-27
Result 2 indicating the PTEN expression regulated by METTL14
Cell Line	mouse embryonic stem cells
Condition	Healthy		Mus musculus
Treatment: METTL14-/- ESCs Control: Wild type ESCs			GSE145309
Regulation			logFC: 8.26E-01 p-value: 8.07E-27

Cite M6AREG

S. P. Liu, L. Chen, Y. T. Zhang, Y. Zhou, Y. He, Z. Chen, S. S. Qi, J. Y. Zhu, X. D. Chen, H. Zhang, Y. C. Luo, Y. Q. Qiu, L. Tao*, F. Zhu*. M6AREG: m6A-centered regulation of disease development and drug response. Nucleic Acids Research. 2022 Sep 22;gkac801. PMID: 36134713

Correspondence

Prof. Feng ZHU

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China

Prof. Shuiping Liu

School of Pharmacy, Hangzhou Normal University, Hangzhou, China

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