m6A Target Genes of This Regulator

General Information of the m6A Regulator (ID: REG00005)
Regulator Name RNA demethylase ALKBH5 (ALKBH5)
Synonyms
Alkylated DNA repair protein alkB homolog 5; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; ABH5; OFOXD1
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Gene Name ALKBH5
Regulator Type ERASER READER WRITER
Regulator Link Click to View Full Information of This Regulator
Full List of Target Gene(s) of This m6A Regulator ( Full Data Download )
Protein coding
Gene with protein product
In total 10958 target gene(s)
1,4-alpha-glucan branching enzyme 1 (GBE1) [1]
HGNC ID HGNC:4180
Ensembl ID ENSG00000114480
Uniprot ID GLGB_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 2.188302867; p-value: 0.010734622
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1) [1]
HGNC ID HGNC:324
Ensembl ID ENSG00000204310
Uniprot ID PLCA_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.610944164; p-value: 0.01955833
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
1-acylglycerol-3-phosphate O-acyltransferase 3 (AGPAT3) [1]
HGNC ID HGNC:326
Ensembl ID ENSG00000160216
Uniprot ID PLCC_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 2.358256798; p-value: 0.000715632
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
1-acylglycerol-3-phosphate O-acyltransferase 4 (AGPAT4) [1]
HGNC ID HGNC:20885
Ensembl ID ENSG00000026652
Uniprot ID PLCD_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.259248681; p-value: 0.004553047
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
1-acylglycerol-3-phosphate O-acyltransferase 5 (AGPAT5) [2]
HGNC ID HGNC:20886
Ensembl ID ENSG00000155189
Uniprot ID PLCE_HUMAN
Method RNA-seq GSE128574
Condition knock down
Evidence logFC: -0.93066375; p-value: 0.002469447
Cell Line THP1 Acute myeloid leukemia Homo sapiens CVCL_0006
15-hydroxyprostaglandin dehydrogenase (HPGD) [3]
HGNC ID HGNC:5154
Ensembl ID ENSG00000164120
Uniprot ID PGDH_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 1.254938958; p-value: 0.00296501
Cell Line Human islet-like organoids Healthy Homo sapiens .
2'-5'-oligoadenylate synthetase 1 (OAS1) [1]
HGNC ID HGNC:8086
Ensembl ID ENSG00000089127
Uniprot ID OAS1_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.007778627; p-value: 0.004802165
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
2'-5'-oligoadenylate synthetase 2 (OAS2) [4]
HGNC ID HGNC:8087
Ensembl ID ENSG00000111335
Uniprot ID OAS2_HUMAN
Method RNA-seq GSE185886
Condition knock down
Evidence logFC: -1.815892165; p-value: 0.000546547
Cell Line Cal27 Tongue squamous cell carcinoma Homo sapiens CVCL_1107
2'-5'-oligoadenylate synthetase 3 (OAS3) [1]
HGNC ID HGNC:8088
Ensembl ID ENSG00000111331
Uniprot ID OAS3_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.737329008; p-value: 0.015676757
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
2'-5'-oligoadenylate synthetase like (OASL) [5]
HGNC ID HGNC:8090
Ensembl ID ENSG00000135114
Uniprot ID OASL_HUMAN
Method RNA-seq GSE154528
Condition knock down
Evidence logFC: 0.907581154; p-value: 0.001657578
Cell Line 143B cell line Osteosarcoma Homo sapiens CVCL_2270
Click to Download All Target Gene of This Genetic Class
Pseudogene
Immunoglobulin pseudogene
In total 3 target gene(s)
Immunoglobulin heavy joining 3P (pseudogene) (IGHJ3P) [7]
HGNC ID HGNC:5537
Ensembl ID ENSG00000237111
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.936790515; p-value: 0.024438776
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy variable 3/OR16-7 (pseudogene) (IGHV3OR16-7) [7]
HGNC ID HGNC:5642
Ensembl ID ENSG00000271620
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.575844497; p-value: 0.000962182
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin lambda variable (I)-70 (pseudogene) (IGLVI-70) [7]
HGNC ID HGNC:5940
Ensembl ID ENSG00000253239
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.065951296; p-value: 0.027162939
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Click to Download All Target Gene of This Genetic Class
Pseudogene
In total 742 target gene(s)
5-hydroxytryptamine receptor 7 pseudogene 1 (HTR7P1) [1]
HGNC ID HGNC:30411
Ensembl ID ENSG00000183935
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.096452702; p-value: 0.002149799
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
AARSD1 pseudogene 1 (AARSD1P1) [7]
HGNC ID HGNC:54994
Ensembl ID ENSG00000234969
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.435648184; p-value: 0.000435523
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Acidic nuclear phosphoprotein 32 family member A pseudogene 1 (ANP32AP1) [1]
HGNC ID HGNC:42949
Ensembl ID ENSG00000259516
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.593931008; p-value: 0.001291548
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
ACTB pseudogene 2 (ACTBP2) [7]
HGNC ID HGNC:135
Ensembl ID ENSG00000213763
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.849495967; p-value: 0.000137872
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Actin family pseudogene 1 (ACTP1) [6]
HGNC ID HGNC:51621
Ensembl ID ENSG00000229890
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 0.661903656; p-value: 0.02273574
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Actin gamma 1 pseudogene 16 (ACTG1P16) [6]
HGNC ID HGNC:51496
Ensembl ID ENSG00000260298
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 1.035673282; p-value: 0.002695532
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Actin gamma 1 pseudogene 20 (ACTG1P20) [2]
HGNC ID HGNC:51500
Ensembl ID ENSG00000241547
Method RNA-seq GSE128574
Condition knock down
Evidence logFC: 1.676350759; p-value: 0.003187405
Cell Line THP1 Acute myeloid leukemia Homo sapiens CVCL_0006
Actin gamma 1 pseudogene 24 (ACTG1P24) [6]
HGNC ID HGNC:49661
Ensembl ID ENSG00000226359
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 0.967971671; p-value: 0.015747695
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Activator of HSP90 ATPase homolog 2, pseudogene (AHSA2P) [6]
HGNC ID HGNC:20437
Ensembl ID ENSG00000173209
Uniprot ID AHSA2_HUMAN
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 0.890968637; p-value: 0.009241442
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Adenosylmethionine decarboxylase 1 pseudogene 4 (AMD1P4) [7]
HGNC ID HGNC:51609
Ensembl ID ENSG00000215124
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.712325417; p-value: 0.007002993
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Click to Download All Target Gene of This Genetic Class
T cell receptor pseudogene
In total 3 target gene(s)
T cell receptor alpha variable 33 (pseudogene) (TRAV33) [3]
HGNC ID HGNC:12132
Ensembl ID ENSG00000258812
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -1.143500364; p-value: 0.000170374
Cell Line Human islet-like organoids Healthy Homo sapiens .
T cell receptor gamma variable 5P (pseudogene) (TRGV5P) [7]
HGNC ID HGNC:12291
Ensembl ID ENSG00000228668
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.822732263; p-value: 0.030813021
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
T cell receptor gamma variable 6 (pseudogene) (TRGV6) [7]
HGNC ID HGNC:12292
Ensembl ID ENSG00000226212
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.291192156; p-value: 0.005923864
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Click to Download All Target Gene of This Genetic Class
Long non-coding
Long non-coding RNA
In total 822 target gene(s)
A1BG antisense RNA 1 (A1BG-AS1) [1]
HGNC ID HGNC:37133
Ensembl ID ENSG00000268895
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.622718525; p-value: 0.046815723
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
ACTR3 antisense RNA 1 (ACTR3-AS1) [7]
HGNC ID HGNC:53965
Ensembl ID ENSG00000228857
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.589094369; p-value: 0.004736059
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
ACVR2B antisense RNA 1 (ACVR2B-AS1) [1]
HGNC ID HGNC:44161
Ensembl ID ENSG00000229589
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.959103823; p-value: 0.006653244
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
ADAMTSL4 antisense RNA 1 (ADAMTSL4-AS1) [7]
HGNC ID HGNC:32041
Ensembl ID ENSG00000203804
Uniprot ID A4AS1_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 2.119782114; p-value: 0.000150969
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
ADAMTSL4 antisense RNA 2 (ADAMTSL4-AS2) [7]
HGNC ID HGNC:40895
Ensembl ID ENSG00000237781
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 2.119782114; p-value: 0.000150969
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
ADORA2A antisense RNA 1 (ADORA2A-AS1) [7]
HGNC ID HGNC:37122
Ensembl ID ENSG00000178803
Uniprot ID AAS1_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.667477843; p-value: 0.009722935
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
AKAP1 divergent transcript (AKAP1-DT) [3]
HGNC ID HGNC:55339
Ensembl ID ENSG00000263004
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 0.731895693; p-value: 3.56E-06
Cell Line Human islet-like organoids Healthy Homo sapiens .
ALG13 antisense RNA 1 (ALG13-AS1) [7]
HGNC ID HGNC:41277
Ensembl ID ENSG00000229487
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.73163394; p-value: 9.47E-05
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
ALMS1 intronic transcript 1 (ALMS1-IT1) [7]
HGNC ID HGNC:41305
Ensembl ID ENSG00000230002
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 4.68550858; p-value: 0.007754552
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
ALOX12 antisense RNA 1 (ALOX12-AS1) [1]
HGNC ID HGNC:51342
Ensembl ID ENSG00000215067
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.483611146; p-value: 7.13E-19
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Click to Download All Target Gene of This Genetic Class
Short non-coding
Micro RNA
In total 116 target gene(s)
MicroRNA 122 (MIR122) [3]
HGNC ID HGNC:31501
Ensembl ID ENSG00000284440
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -0.631887998; p-value: 0.024431084
Cell Line Human islet-like organoids Healthy Homo sapiens .
MicroRNA 1229 (MIR1229) [3]
HGNC ID HGNC:33924
Ensembl ID ENSG00000221394
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 0.612336502; p-value: 1.71E-06
Cell Line Human islet-like organoids Healthy Homo sapiens .
MicroRNA 124-1 (MIR124-1) [1]
HGNC ID HGNC:31502
Ensembl ID ENSG00000284321
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.708704697; p-value: 0.007631128
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
MicroRNA 1244-3 (MIR1244-3) [3]
HGNC ID HGNC:38390
Ensembl ID ENSG00000283429
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -0.779410201; p-value: 0.004107803
Cell Line Human islet-like organoids Healthy Homo sapiens .
MicroRNA 1282 (MIR1282) [1]
HGNC ID HGNC:35360
Ensembl ID ENSG00000221792
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.710121666; p-value: 0.033667654
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
MicroRNA 1290 (MIR1290) [6]
HGNC ID HGNC:35283
Ensembl ID ENSG00000221662
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: -2.93279709; p-value: 0.004111848
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
MicroRNA 1304 (MIR1304) [3]
HGNC ID HGNC:35302
Ensembl ID ENSG00000284458
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -1.964091534; p-value: 3.50E-05
Cell Line Human islet-like organoids Healthy Homo sapiens .
MicroRNA 142 (MIR142) [1]
HGNC ID HGNC:31529
Ensembl ID ENSG00000284353
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.087620885; p-value: 0.001976567
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
MicroRNA 147b (MIR147B) [3]
HGNC ID HGNC:33655
Ensembl ID ENSG00000284386
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 0.591470128; p-value: 0.013090125
Cell Line Human islet-like organoids Healthy Homo sapiens .
MicroRNA 1827 (MIR1827) [7]
HGNC ID HGNC:35391
Ensembl ID ENSG00000221476
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.712479989; p-value: 0.012283532
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
Click to Download All Target Gene of This Genetic Class
Misc RNA
In total 2 target gene(s)
Ribonuclease P RNA component H1 (RPPH1) [1]
HGNC ID HGNC:19273
Ensembl ID ENSG00000277209
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.684306804; p-value: 0.01797232
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
RNA component of mitochondrial RNA processing endoribonuclease (RMRP) [1]
HGNC ID HGNC:10031
Ensembl ID ENSG00000277027
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.746266849; p-value: 7.64E-06
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Click to Download All Target Gene of This Genetic Class
Ribosomal RNA
In total 4 target gene(s)
RNA, 5.8S ribosomal N1 (RNA5-8SN1) [3]
HGNC ID HGNC:53517
Ensembl ID ENSG00000278189
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 1.147505165; p-value: 5.92E-05
Cell Line Human islet-like organoids Healthy Homo sapiens .
RNA, 5.8S ribosomal N2 (RNA5-8SN2) [3]
HGNC ID HGNC:53521
Ensembl ID ENSG00000278233
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -0.680559181; p-value: 4.31E-05
Cell Line Human islet-like organoids Healthy Homo sapiens .
RNA, 5.8S ribosomal N3 (RNA5-8SN3) [7]
HGNC ID HGNC:53525
Ensembl ID ENSG00000275215
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.596112912; p-value: 0.00410604
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
RNA, 5S ribosomal 9 (RNA5S9) [6]
HGNC ID HGNC:34370
Ensembl ID ENSG00000201321
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: -0.698009423; p-value: 0.034635838
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Click to Download All Target Gene of This Genetic Class
Small nuclear RNA
In total 19 target gene(s)
RNA, U1 small nuclear 1 (RNU1-1) [6]
HGNC ID HGNC:10120
Ensembl ID ENSG00000206652
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 0.837627582; p-value: 0.00130922
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
RNA, U1 small nuclear 2 (RNU1-2) [6]
HGNC ID HGNC:10123
Ensembl ID ENSG00000207005
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: -2.254738021; p-value: 3.03E-05
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
RNA, U11 small nuclear (RNU11) [1]
HGNC ID HGNC:10108
Ensembl ID ENSG00000274978
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.433561391; p-value: 0.001696046
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
RNA, U12 small nuclear (RNU12) [1]
HGNC ID HGNC:19380
Ensembl ID ENSG00000276027
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.140039707; p-value: 0.002358256
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
RNA, U4 small nuclear 1 (RNU4-1) [1]
HGNC ID HGNC:10192
Ensembl ID ENSG00000200795
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.826840158; p-value: 0.002506378
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
RNA, U4 small nuclear 2 (RNU4-2) [1]
HGNC ID HGNC:10193
Ensembl ID ENSG00000202538
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.183975163; p-value: 0.048973099
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
RNA, U4atac small nuclear (RNU4ATAC) [1]
HGNC ID HGNC:34016
Ensembl ID ENSG00000264229
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.060492033; p-value: 0.001168493
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
RNA, U5A small nuclear 1 (RNU5A-1) [7]
HGNC ID HGNC:10211
Ensembl ID ENSG00000199568
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.8234359; p-value: 0.036299515
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
RNA, U5B small nuclear 1 (RNU5B-1) [7]
HGNC ID HGNC:10212
Ensembl ID ENSG00000200156
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.744826111; p-value: 1.71E-05
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
RNA, U5F small nuclear 1 (RNU5F-1) [1]
HGNC ID HGNC:10216
Ensembl ID ENSG00000199377
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.713986961; p-value: 0.00033613
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Click to Download All Target Gene of This Genetic Class
Small nucleolar RNA
In total 88 target gene(s)
Small Cajal body-specific RNA 1 (SCARNA1) [6]
HGNC ID HGNC:32555
Ensembl ID ENSG00000252947
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 0.696800249; p-value: 0.003325405
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Small Cajal body-specific RNA 10 (SCARNA10) [1]
HGNC ID HGNC:32567
Ensembl ID ENSG00000239002
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.769984789; p-value: 2.90E-06
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Small Cajal body-specific RNA 11 (SCARNA11) [7]
HGNC ID HGNC:32568
Ensembl ID ENSG00000251898
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.114047948; p-value: 0.003997395
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Small Cajal body-specific RNA 12 (SCARNA12) [8]
HGNC ID HGNC:32569
Ensembl ID ENSG00000238795
Method RNA-seq GSE78040
Condition knock down
Evidence logFC: 0.940186688; p-value: 0.013218306
Cell Line HEK293T Healthy Homo sapiens CVCL_0045
Small Cajal body-specific RNA 14 (SCARNA14) [5]
HGNC ID HGNC:32571
Ensembl ID ENSG00000252712
Method RNA-seq GSE154528
Condition knock down
Evidence logFC: 0.919723194; p-value: 0.002746386
Cell Line 143B cell line Osteosarcoma Homo sapiens CVCL_2270
Small Cajal body-specific RNA 16 (SCARNA16) [1]
HGNC ID HGNC:32573
Ensembl ID ENSG00000275143
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.72418188; p-value: 0.001851041
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Small Cajal body-specific RNA 17 (SCARNA17) [1]
HGNC ID HGNC:32574
Ensembl ID ENSG00000251992
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.825083374; p-value: 0.025722896
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Small Cajal body-specific RNA 18 (SCARNA18) [1]
HGNC ID HGNC:32559
Ensembl ID ENSG00000238835
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.844858312; p-value: 0.002101486
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Small Cajal body-specific RNA 2 (SCARNA2) [1]
HGNC ID HGNC:32558
Ensembl ID ENSG00000278249
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.693892393; p-value: 0.007510348
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Small Cajal body-specific RNA 3 (SCARNA3) [1]
HGNC ID HGNC:32577
Ensembl ID ENSG00000252906
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.130109972; p-value: 0.046582885
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Click to Download All Target Gene of This Genetic Class
Transfer RNA
In total 8 target gene(s)
Mitochondrially encoded tRNA-Arg (CGN) (MT-TR) [6]
HGNC ID HGNC:7496
Ensembl ID ENSG00000210174
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: 0.764938781; p-value: 0.019594456
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Mitochondrially encoded tRNA-Cys (UGU/C) (MT-TC) [6]
HGNC ID HGNC:7477
Ensembl ID ENSG00000210140
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: -0.729144658; p-value: 0.04473143
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
Mitochondrially encoded tRNA-Gln (CAA/G) (MT-TQ) [7]
HGNC ID HGNC:7495
Ensembl ID ENSG00000210107
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.653719919; p-value: 0.033290655
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Mitochondrially encoded tRNA-Glu (GAA/G) (MT-TE) [7]
HGNC ID HGNC:7479
Ensembl ID ENSG00000210194
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.795006999; p-value: 0.008373128
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Mitochondrially encoded tRNA-Leu (UUA/G) 1 (MT-TL1) [7]
HGNC ID HGNC:7490
Ensembl ID ENSG00000209082
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.762517069; p-value: 0.018495065
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
Mitochondrially encoded tRNA-Met (AUA/G) (MT-TM) [7]
HGNC ID HGNC:7492
Ensembl ID ENSG00000210112
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.806738568; p-value: 0.038191178
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
Mitochondrially encoded tRNA-Trp (UGA/G) (MT-TW) [7]
HGNC ID HGNC:7501
Ensembl ID ENSG00000210117
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.588692755; p-value: 0.044613849
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Mitochondrially encoded tRNA-Val (GUN) (MT-TV) [7]
HGNC ID HGNC:7500
Ensembl ID ENSG00000210077
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.208344967; p-value: 0.03466601
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Click to Download All Target Gene of This Genetic Class
Vault RNA
In total 1 target gene(s)
Vault RNA 1-1 (VTRNA1-1) [1]
HGNC ID HGNC:12654
Ensembl ID ENSG00000199990
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.126044848; p-value: 0.001555921
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Click to Download All Target Gene of This Genetic Class
Other
Complex locus constituent
In total 9 target gene(s)
Protocadherin alpha 11 (PCDHA11) [6]
HGNC ID HGNC:8665
Ensembl ID ENSG00000249158
Uniprot ID PCDAB_HUMAN
Method RNA-seq GSE182382
Condition knock down
Evidence logFC: -0.711925269; p-value: 0.020852639
Cell Line DKO-1 Colorectal cancer Homo sapiens CVCL_9798
UDP glucuronosyltransferase family 1 member A1 (UGT1A1) [3]
HGNC ID HGNC:12530
Ensembl ID ENSG00000241635
Uniprot ID UD11_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 1.284849545; p-value: 0.000149879
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A10 (UGT1A10) [3]
HGNC ID HGNC:12531
Ensembl ID ENSG00000242515
Uniprot ID UD110_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -0.976523039; p-value: 0.000200679
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A2, pseudogene (UGT1A2P) [3]
HGNC ID HGNC:12534
Ensembl ID ENSG00000228445
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -0.763788838; p-value: 0.036921399
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A4 (UGT1A4) [3]
HGNC ID HGNC:12536
Ensembl ID ENSG00000244474
Uniprot ID UD14_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -1.952532812; p-value: 0.000266016
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A6 (UGT1A6) [3]
HGNC ID HGNC:12538
Ensembl ID ENSG00000167165
Uniprot ID UD16_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -2.081543804; p-value: 0.003509435
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A7 (UGT1A7) [3]
HGNC ID HGNC:12539
Ensembl ID ENSG00000244122
Uniprot ID UD17_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 0.761348338; p-value: 0.008924087
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A8 (UGT1A8) [3]
HGNC ID HGNC:12540
Ensembl ID ENSG00000242366
Uniprot ID UD18_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 2.893732707; p-value: 0.000130276
Cell Line Human islet-like organoids Healthy Homo sapiens .
UDP glucuronosyltransferase family 1 member A9 (UGT1A9) [3]
HGNC ID HGNC:12541
Ensembl ID ENSG00000241119
Uniprot ID UD19_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -3.174999091; p-value: 1.65E-06
Cell Line Human islet-like organoids Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Endogenous retrovirus
In total 1 target gene(s)
Endogenous retrovirus group K13 member 1 (ERVK13-1) [1]
HGNC ID HGNC:27548
Ensembl ID ENSG00000260565
Uniprot ID ENK13_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.146871775; p-value: 1.98E-05
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Click to Download All Target Gene of This Genetic Class
Immunoglobulin gene
In total 19 target gene(s)
Immunoglobulin heavy constant alpha 1 (IGHA1) [7]
HGNC ID HGNC:5478
Ensembl ID ENSG00000211895
Uniprot ID IGHA1_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.720656294; p-value: 0.040280795
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy constant alpha 2 (A2m marker) (IGHA2) [7]
HGNC ID HGNC:5479
Ensembl ID ENSG00000211890
Uniprot ID IGHA2_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.137306052; p-value: 0.045036289
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
Immunoglobulin heavy constant epsilon (IGHE) [7]
HGNC ID HGNC:5522
Ensembl ID ENSG00000211891
Uniprot ID IGHE_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.893106424; p-value: 0.011261064
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy constant gamma 1 (G1m marker) (IGHG1) [7]
HGNC ID HGNC:5525
Ensembl ID ENSG00000211896
Uniprot ID IGHG1_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -5.180816477; p-value: 0.048900564
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy constant gamma 2 (G2m marker) (IGHG2) [7]
HGNC ID HGNC:5526
Ensembl ID ENSG00000211893
Uniprot ID IGHG2_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.091469394; p-value: 0.046842388
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy constant gamma 3 (G3m marker) (IGHG3) [7]
HGNC ID HGNC:5527
Ensembl ID ENSG00000211897
Uniprot ID IGHG3_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.378763874; p-value: 0.001589115
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy constant gamma 4 (G4m marker) (IGHG4) [7]
HGNC ID HGNC:5528
Ensembl ID ENSG00000211892
Uniprot ID IGHG4_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -2.73039105; p-value: 0.015302918
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin heavy joining 6 (IGHJ6) [7]
HGNC ID HGNC:5540
Ensembl ID ENSG00000211900
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.818794097; p-value: 0.007706945
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin kappa constant (IGKC) [7]
HGNC ID HGNC:5716
Ensembl ID ENSG00000211592
Uniprot ID IGKC_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.397753599; p-value: 0.013713079
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Immunoglobulin kappa variable 1/OR2-108 (non-functional) (IGKV1OR2-108) [2]
HGNC ID HGNC:5767
Ensembl ID ENSG00000231292
Method RNA-seq GSE128574
Condition knock down
Evidence logFC: -1.034472579; p-value: 0.035506578
Cell Line THP1 Acute myeloid leukemia Homo sapiens CVCL_0006
Click to Download All Target Gene of This Genetic Class
Protocadherin
In total 5 target gene(s)
Protocadherin beta 5 (PCDHB5) [2]
HGNC ID HGNC:8690
Ensembl ID ENSG00000113209
Uniprot ID PCDB5_HUMAN
Method RNA-seq GSE128574
Condition knock down
Evidence logFC: -1.322258409; p-value: 0.000850231
Cell Line THP1 Acute myeloid leukemia Homo sapiens CVCL_0006
Protocadherin beta 6 (PCDHB6) [7]
HGNC ID HGNC:8691
Ensembl ID ENSG00000113211
Uniprot ID PCDB6_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.011196203; p-value: 0.000247277
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Protocadherin gamma subfamily A, 11 (PCDHGA11) [1]
HGNC ID HGNC:8698
Ensembl ID ENSG00000253873
Uniprot ID PCDGB_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.005182847; p-value: 0.001583188
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Protocadherin gamma subfamily C, 3 (PCDHGC3) [1]
HGNC ID HGNC:8716
Ensembl ID ENSG00000240184
Uniprot ID PCDGK_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.798551613; p-value: 0.009040726
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Protocadherin gamma subfamily C, 5 (PCDHGC5) [1]
HGNC ID HGNC:8718
Ensembl ID ENSG00000240764
Uniprot ID PCDGM_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -1.079986209; p-value: 0.002368009
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Click to Download All Target Gene of This Genetic Class
Readthrough
In total 44 target gene(s)
ARMCX5-GPRASP2 readthrough (ARMCX5-GPRASP2) [1]
HGNC ID HGNC:42000
Ensembl ID ENSG00000271147
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.7047356; p-value: 0.006107494
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
ARPC4-TTLL3 readthrough (ARPC4-TTLL3) [1]
HGNC ID HGNC:38830
Ensembl ID ENSG00000250151
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 1.672389721; p-value: 0.006539046
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
ATF7-NPFF readthrough (ATF7-NPFF) [4]
HGNC ID HGNC:55073
Ensembl ID ENSG00000267281
Method RNA-seq GSE185886
Condition knock down
Evidence logFC: -0.942053341; p-value: 0.027408493
Cell Line Cal27 Tongue squamous cell carcinoma Homo sapiens CVCL_1107
BIVM-ERCC5 readthrough (BIVM-ERCC5) [1]
HGNC ID HGNC:43690
Ensembl ID ENSG00000270181
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.854030924; p-value: 2.91E-12
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
BLOC1S5-TXNDC5 readthrough (NMD candidate) (BLOC1S5-TXNDC5) [1]
HGNC ID HGNC:42001
Ensembl ID ENSG00000259040
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.984195713; p-value: 2.34E-26
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
BOLA2-SMG1P6 readthrough (BOLA2-SMG1P6) [1]
HGNC ID HGNC:53563
Ensembl ID ENSG00000261740
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.592425943; p-value: 0.044933024
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
BORCS7-ASMT readthrough (NMD candidate) (BORCS7-ASMT) [8]
HGNC ID HGNC:49183
Ensembl ID ENSG00000270316
Method RNA-seq GSE78040
Condition knock down
Evidence logFC: -0.663259289; p-value: 0.023832953
Cell Line HEK293T Healthy Homo sapiens CVCL_0045
C1QTNF3-AMACR readthrough (NMD candidate) (C1QTNF3-AMACR) [1]
HGNC ID HGNC:49198
Ensembl ID ENSG00000273294
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.62255753; p-value: 0.001031128
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
C8orf44-SGK3 readthrough (C8orf44-SGK3) [1]
HGNC ID HGNC:48354
Ensembl ID ENSG00000288602
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.835578911; p-value: 3.01E-07
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
CCL15-CCL14 readthrough (NMD candidate) (CCL15-CCL14) [3]
HGNC ID HGNC:44436
Ensembl ID ENSG00000275688
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: 3.046391414; p-value: 0.004191652
Cell Line Human islet-like organoids Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
T cell receptor gene
In total 8 target gene(s)
T cell receptor alpha variable 18 (TRAV18) [7]
HGNC ID HGNC:12114
Ensembl ID ENSG00000211798
Uniprot ID TVA18_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.720359789; p-value: 0.043443527
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
T cell receptor beta constant 1 (TRBC1) [7]
HGNC ID HGNC:12156
Ensembl ID ENSG00000211751
Uniprot ID TRBC1_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.339916454; p-value: 0.004099616
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
T cell receptor beta constant 2 (TRBC2) [7]
HGNC ID HGNC:12157
Ensembl ID ENSG00000211772
Uniprot ID TRBC2_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.626095879; p-value: 0.04229514
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
T cell receptor beta joining 2-4 (TRBJ2-4) [7]
HGNC ID HGNC:12172
Ensembl ID ENSG00000211768
Uniprot ID TJB24_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -1.076573173; p-value: 0.008492948
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
T cell receptor beta variable 10-3 (TRBV10-3) [7]
HGNC ID HGNC:12179
Ensembl ID ENSG00000275791
Uniprot ID TVBJ3_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.648901737; p-value: 0.017395347
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
T cell receptor beta variable 2 (TRBV2) [7]
HGNC ID HGNC:12195
Ensembl ID ENSG00000226660
Uniprot ID TVB2_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: -0.688770772; p-value: 0.027651785
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
T cell receptor beta variable 6-6 (TRBV6-6) [7]
HGNC ID HGNC:12231
Ensembl ID ENSG00000211724
Uniprot ID TVB66_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.705779185; p-value: 0.0030281
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
T cell receptor delta diversity 3 (TRDD3) [7]
HGNC ID HGNC:12256
Ensembl ID ENSG00000228985
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 1.004869565; p-value: 0.038588892
Cell Line CAG cell line Multiple myeloma Homo sapiens CVCL_D569
Click to Download All Target Gene of This Genetic Class
Unknown
In total 10 target gene(s)
Adhesion G protein-coupled receptor F2 (ADGRF2) [4]
HGNC ID HGNC:18991
Ensembl ID ENSG00000164393
Uniprot ID AGRF2_HUMAN
Method RNA-seq GSE185886
Condition knock down
Evidence logFC: -0.635976813; p-value: 0.001039008
Cell Line Cal27 Tongue squamous cell carcinoma Homo sapiens CVCL_1107
Chromosome 1 putative open reading frame 220 (C1orf220) [8]
HGNC ID HGNC:33805
Ensembl ID ENSG00000213057
Uniprot ID CA220_HUMAN
Method RNA-seq GSE78040
Condition knock down
Evidence logFC: -1.751952229; p-value: 0.017346907
Cell Line HEK293T Healthy Homo sapiens CVCL_0045
Chromosome 19 putative open reading frame 48 (C19orf48) [1]
HGNC ID HGNC:29667
Ensembl ID ENSG00000167747
Uniprot ID CS048_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.97743731; p-value: 0.006955313
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Chromosome 22 putative open reading frame 46 (C22orf46) [5]
HGNC ID HGNC:26294
Ensembl ID ENSG00000184208
Uniprot ID CV046_HUMAN
Method RNA-seq GSE154528
Condition knock down
Evidence logFC: 0.760241302; p-value: 0.01401234
Cell Line 143B cell line Osteosarcoma Homo sapiens CVCL_2270
Chromosome 5 putative open reading frame 67 (C5orf67) [3]
HGNC ID HGNC:51252
Ensembl ID ENSG00000225940
Uniprot ID CE067_HUMAN
Method RNA-seq GSE163945
Condition knock out
Evidence logFC: -1.640541048; p-value: 0.026114307
Cell Line Human islet-like organoids Healthy Homo sapiens .
Chromosome 8 putative open reading frame 44 (C8orf44) [1]
HGNC ID HGNC:25646
Ensembl ID ENSG00000288596
Uniprot ID CH044_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.670039322; p-value: 0.034822851
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Long intergenic non-protein coding RNA 672 (LINC00672) [1]
HGNC ID HGNC:44353
Ensembl ID ENSG00000263874
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.713346599; p-value: 0.000272221
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Nuclear factor, erythroid 4 (NFE4) [1]
HGNC ID HGNC:29902
Ensembl ID ENSG00000230257
Uniprot ID NFE4_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: 0.627539229; p-value: 0.00505338
Cell Line NOMO1 Acute myeloid leukemia Homo sapiens CVCL_1609
Orofacial cleft 1 candidate 1 (OFCC1) [7]
HGNC ID HGNC:21017
Ensembl ID ENSG00000181355
Uniprot ID OFCC1_HUMAN
Method RNA-seq GSE180214
Condition knock down
Evidence logFC: 0.846898509; p-value: 0.009761111
Cell Line RPMI-8226 cell line Multiple myeloma Homo sapiens CVCL_0014
Proapoptotic nucleolar protein 1 (PANO1) [1]
HGNC ID HGNC:51237
Ensembl ID ENSG00000288675
Uniprot ID PANO1_HUMAN
Method RNA-seq GSE144968
Condition knock down
Evidence logFC: -0.81937722; p-value: 0.019280391
Cell Line MOLM13 Acute myeloid leukemia Homo sapiens CVCL_2119
Click to Download All Target Gene of This Genetic Class
References
Ref 1 RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020 Jul 2;27(1):64-80.e9. doi: 10.1016/j.stem.2020.04.009. Epub 2020 May 12.
Ref 2 Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell. 2020 Jul 2;27(1):81-97.e8. doi: 10.1016/j.stem.2020.04.001. Epub 2020 May 12.
Ref 3 N(6)-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis. Nat Commun. 2022 Jul 18;13(1):4148.
Ref 4 The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKEpsilon/TBK1/IRF3 pathway in head and neck squamous cell carcinoma. Mol Cancer. 2022 Apr 9;21(1):97. doi: 10.1186/s12943-022-01572-2.
Ref 5 M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression. Cancer Res. 2022 May 16;82(10):1872-1889. doi: 10.1158/0008-5472.CAN-21-2106.
Ref 6 Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m(6)A consensus sequences. Heliyon. 2021 Dec 2;7(12):e08519.
Ref 7 RNA demethylase ALKBH5 promotes tumorigenesis in multiple myeloma [RNA-seq]
Ref 8 Reversible methylation of m(6)A(m) in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541(7637):371-375.
Ref 9 Effect of depletion of ALKBH5 on gene expression of HaCAT human keratinocyte cell line