Regulator ID	target symbol	target name	hgnc_id	ensembl_gene_id	uniprot ID	Entrez_id	type	type_class	cell_line	cell_id	species	cell_disease	ICD_disease	method	PMID	GSE	log2FoldChange	perturbation	direction	pvalue
REG00005	INS-IGF2	INS-IGF2 readthrough	HGNC:33527	ENSG00000129965	INSR2_HUMAN	723961	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	-1.544455259	knock out	down-regulator	1.78E-06
REG00005	NME1-NME2	NME1-NME2 readthrough	HGNC:33531	ENSG00000011052	.	654364	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	1.339204212	knock down	up-regulate	0.007404782
REG00005	TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough	HGNC:33537	ENSG00000248871	.	407977	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-2.967773212	knock down	down-regulator	0.000501599
REG00005	TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough	HGNC:33537	ENSG00000248871	.	407977	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	4.518042341	knock out	up-regulate	7.37E-05
REG00005	TMED7-TICAM2	TMED7-TICAM2 readthrough	HGNC:33945	ENSG00000251201	.	100302736	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	1.830065334	knock down	up-regulate	0.008548846
REG00005	JMJD7-PLA2G4B	JMJD7-PLA2G4B readthrough	HGNC:34449	ENSG00000168970	.	8681	Readthrough	Other	THP1	CVCL_0006	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402251	GSE128574	0.877740559	knock down	up-regulate	4.15E-05
REG00005	PRR5-ARHGAP8	PRR5-ARHGAP8 readthrough	HGNC:34512	ENSG00000248405	.	553158	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.898546736	knock down	down-regulator	0.015747992
REG00005	LY75-CD302	LY75-CD302 readthrough	HGNC:38828	ENSG00000248672	.	100526664	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	0.892782753	knock down	up-regulate	6.40E-05
REG00005	LY75-CD302	LY75-CD302 readthrough	HGNC:38828	ENSG00000248672	.	100526664	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	-1.6819027	knock out	down-regulator	6.78E-07
REG00005	ARPC4-TTLL3	ARPC4-TTLL3 readthrough	HGNC:38830	ENSG00000250151	.	100526693	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	1.672389721	knock down	up-regulate	0.006539046
REG00005	ARPC4-TTLL3	ARPC4-TTLL3 readthrough	HGNC:38830	ENSG00000250151	.	100526693	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-1.560944918	knock down	down-regulator	2.08E-17
REG00005	ARPC4-TTLL3	ARPC4-TTLL3 readthrough	HGNC:38830	ENSG00000250151	.	100526693	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	1.030637395	knock down	up-regulate	2.29E-09
REG00005	MSANTD3-TMEFF1	MSANTD3-TMEFF1 readthrough	HGNC:38838	ENSG00000251349	.	100526694	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	-1.368031301	knock out	down-regulator	0.049033788
REG00005	MSANTD3-TMEFF1	MSANTD3-TMEFF1 readthrough	HGNC:38838	ENSG00000251349	.	100526694	Readthrough	Other	HEK293T	CVCL_0045	Homo sapiens	Healthy	.	RNA-seq	28002401	GSE78040	-0.809286302	knock down	down-regulator	0.034166481
REG00005	RBM14-RBM4	RBM14-RBM4 readthrough	HGNC:38840	ENSG00000248643	.	100526737	Readthrough	Other	CAG cell line	CVCL_D569	Homo sapiens	Multiple myeloma	2A83: Multiple myeloma	RNA-seq	.	GSE180214	-0.928372687	knock down	down-regulator	0.028248275
REG00005	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough	HGNC:38842	ENSG00000283154	IQIP1_HUMAN	100505385	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.790378605	knock down	down-regulator	0.043885465
REG00005	RNF103-CHMP3	RNF103-CHMP3 readthrough	HGNC:38847	ENSG00000249884	.	100526767	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	1.083056018	knock down	up-regulate	0.004453553
REG00005	RNF103-CHMP3	RNF103-CHMP3 readthrough	HGNC:38847	ENSG00000249884	.	100526767	Readthrough	Other	HEK293T	CVCL_0045	Homo sapiens	Healthy	.	RNA-seq	28002401	GSE78040	0.791520264	knock down	up-regulate	0.01842673
REG00005	NEDD8-MDP1	NEDD8-MDP1 readthrough	HGNC:39551	ENSG00000255526	.	100528064	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	0.678821274	knock down	up-regulate	0.001882157
REG00005	FXYD6-FXYD2	FXYD6-FXYD2 readthrough	HGNC:39978	ENSG00000255245	.	100533181	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	1.062147133	knock out	up-regulate	2.16E-07
REG00005	GPR75-ASB3	GPR75-ASB3 readthrough	HGNC:40043	ENSG00000270898	.	100302652	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	-0.728480154	knock down	down-regulator	0.049480431
REG00005	STX16-NPEPL1	STX16-NPEPL1 readthrough (NMD candidate)	HGNC:41993	ENSG00000254995	.	100534593	Readthrough	Other	DKO-1	CVCL_9798	Homo sapiens	Colorectal cancer	2B91: Colorectal cancer	RNA-seq	34934837	GSE182382	0.620142253	knock down	up-regulate	0.026055404
REG00005	MSH5-SAPCD1	MSH5-SAPCD1 readthrough (NMD candidate)	HGNC:41994	ENSG00000255152	.	100532732	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	0.59061883	knock down	up-regulate	0.014676363
REG00005	CHKB-CPT1B	CHKB-CPT1B readthrough (NMD candidate)	HGNC:41998	ENSG00000254413	.	386593	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.743002833	knock down	down-regulator	0.013417003
REG00005	ARMCX5-GPRASP2	ARMCX5-GPRASP2 readthrough	HGNC:42000	ENSG00000271147	.	100528062	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.7047356	knock down	down-regulator	0.006107494
REG00005	BLOC1S5-TXNDC5	BLOC1S5-TXNDC5 readthrough (NMD candidate)	HGNC:42001	ENSG00000259040	.	100526836	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	0.984195713	knock down	up-regulate	2.34E-26
REG00005	PMF1-BGLAP	PMF1-BGLAP readthrough	HGNC:42953	ENSG00000260238	.	100527963	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.653589722	knock down	down-regulator	0.009205955
REG00005	POC1B-GALNT4	POC1B-GALNT4 readthrough	HGNC:42957	ENSG00000259075	.	100528030	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	0.698184232	knock down	up-regulate	0.028525192
REG00005	TVP23C-CDRT4	TVP23C-CDRT4 readthrough	HGNC:42961	ENSG00000259024	.	100533496	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-1.56294376	knock down	down-regulator	0.001414028
REG00005	ZNF559-ZNF177	ZNF559-ZNF177 readthrough	HGNC:42964	ENSG00000270011	.	100529215	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	-1.576726742	knock down	down-regulator	0.018362171
REG00005	ISY1-RAB43	ISY1-RAB43 readthrough	HGNC:42969	ENSG00000261796	.	100534599	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-1.061993214	knock down	down-regulator	0.000683507
REG00005	ZHX1-C8orf76	ZHX1-C8orf76 readthrough	HGNC:42975	ENSG00000259305	ZHX1R_HUMAN	100533106	Readthrough	Other	THP1	CVCL_0006	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402251	GSE128574	5.134493322	knock down	up-regulate	0.003441204
REG00005	BIVM-ERCC5	BIVM-ERCC5 readthrough	HGNC:43690	ENSG00000270181	.	100533467	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.854030924	knock down	down-regulator	2.91E-12
REG00005	BIVM-ERCC5	BIVM-ERCC5 readthrough	HGNC:43690	ENSG00000270181	.	100533467	Readthrough	Other	HEK293T	CVCL_0045	Homo sapiens	Healthy	.	RNA-seq	28002401	GSE78040	-0.854030924	knock down	down-regulator	2.91E-12
REG00005	PTGES3L-AARSD1	PTGES3L-AARSD1 readthrough	HGNC:43946	ENSG00000108825	AASD1_HUMAN	100885850	Readthrough	Other	THP1	CVCL_0006	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402251	GSE128574	-1.265560501	knock down	down-regulator	0.000810947
REG00005	RTEL1-TNFRSF6B	RTEL1-TNFRSF6B readthrough (NMD candidate)	HGNC:44095	ENSG00000026036	.	100533107	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	0.65592586	knock down	up-regulate	0.022745444
REG00005	CCL15-CCL14	CCL15-CCL14 readthrough (NMD candidate)	HGNC:44436	ENSG00000275688	.	348249	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	3.046391414	knock out	up-regulate	0.004191652
REG00005	SLX1A-SULT1A3	SLX1A-SULT1A3 readthrough (NMD candidate)	HGNC:44437	ENSG00000213599	.	100526830	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	0.914768783	knock down	up-regulate	0.002068098
REG00005	RPL17-C18orf32	RPL17-C18orf32 readthrough	HGNC:44661	ENSG00000215472	.	100526842	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.742858938	knock down	down-regulator	0.013385991
REG00005	NPHP3-ACAD11	NPHP3-ACAD11 readthrough (NMD candidate)	HGNC:48351	ENSG00000274810	.	100532724	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.774030817	knock down	down-regulator	0.013154655
REG00005	SLX1B-SULT1A4	SLX1B-SULT1A4 readthrough (NMD candidate)	HGNC:48353	ENSG00000260280	.	100526831	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	0.798101964	knock down	up-regulate	0.000936619
REG00005	C8orf44-SGK3	C8orf44-SGK3 readthrough	HGNC:48354	ENSG00000288602	.	100533105	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.835578911	knock down	down-regulator	3.01E-07
REG00005	MROH7-TTC4	MROH7-TTC4 readthrough (NMD candidate)	HGNC:49180	ENSG00000271723	.	100527960	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	0.814674965	knock down	up-regulate	0.004306418
REG00005	RPS10-NUDT3	RPS10-NUDT3 readthrough	HGNC:49181	ENSG00000270800	.	100529239	Readthrough	Other	HEK293T	CVCL_0045	Homo sapiens	Healthy	.	RNA-seq	28002401	GSE78040	-1.606575189	knock down	down-regulator	0.011149318
REG00005	BORCS7-ASMT	BORCS7-ASMT readthrough (NMD candidate)	HGNC:49183	ENSG00000270316	.	100528007	Readthrough	Other	HEK293T	CVCL_0045	Homo sapiens	Healthy	.	RNA-seq	28002401	GSE78040	-0.663259289	knock down	down-regulator	0.023832953
REG00005	EEF1E1-BLOC1S5	EEF1E1-BLOC1S5 readthrough (NMD candidate)	HGNC:49187	ENSG00000265818	.	100526837	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.86628834	knock down	down-regulator	0.001792159
REG00005	TM4SF19-DYNLT2B	TM4SF19-DYNLT2B readthrough (NMD candidate)	HGNC:49190	ENSG00000273331	.	100534611	Readthrough	Other	Human islet-like organoids	.	Homo sapiens	Healthy	.	RNA-seq	35851388	GSE163945	0.716183352	knock out	up-regulate	0.009662692
REG00005	C1QTNF3-AMACR	C1QTNF3-AMACR readthrough (NMD candidate)	HGNC:49198	ENSG00000273294	.	100534612	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.62255753	knock down	down-regulator	0.001031128
REG00005	C1QTNF3-AMACR	C1QTNF3-AMACR readthrough (NMD candidate)	HGNC:49198	ENSG00000273294	.	100534612	Readthrough	Other	NOMO1	CVCL_1609	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.920253395	knock down	down-regulator	0.001858912
REG00005	GIMAP1-GIMAP5	GIMAP1-GIMAP5 readthrough	HGNC:51257	ENSG00000281887	.	100527949	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.680952082	knock down	down-regulator	0.000788744
REG00005	BOLA2-SMG1P6	BOLA2-SMG1P6 readthrough	HGNC:53563	ENSG00000261740	.	107282092	Readthrough	Other	MOLM13	CVCL_2119	Homo sapiens	Acute myeloid leukemia	2A60: Acute myeloid leukaemia	RNA-seq	32402250	GSE144968	-0.592425943	knock down	down-regulator	0.044933024
REG00005	ATF7-NPFF	ATF7-NPFF readthrough	HGNC:55073	ENSG00000267281	.	114108587	Readthrough	Other	Cal27	CVCL_1107	Homo sapiens	Tongue squamous cell carcinoma	2B62: Tongue cancer	RNA-seq	35395767	GSE185886	-0.942053341	knock down	down-regulator	0.027408493