m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01739)

Target Name	Kremen protein 1 (KRM1)
Synonyms	Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose Click to Show/Hide
Gene Name	Krm1
Chromosomal Location	22q12.1
Function	Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation. Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification. Click to Show/Hide
Gene ID	83999
Uniprot ID	KREM1_HUMAN
HGNC ID	HGNC:17550
KEGG ID	hsa:83999

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05206		Crosstalk Info
Epigenetic Regulator	Circ_HIPK3
Regulated Target	Insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2)
Crosstalk relationship	ncRNA → m6A
Disease	Calcific aortic valve disease	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01739)

Kremen protein 1 (KRM1)

Adenosine-to-Inosine editing (A-to-I)

In total 7 m6A sequence/site(s) in this target gene
mod ID: A2ISITE011156		Click to Show/Hide the Full List
mod site	chr22:29118442-29118443:+		[2]
Sequence	AGTTTGGGCTGCTGTAACAAAATACCATAGAGTGGGTGGCT
Transcript ID List	ENST00000327813.9; ENST00000407188.5; ENST00000400335.8
External Link	RMBase: RNA-editing_site_91719
mod ID: A2ISITE011157		Click to Show/Hide the Full List
mod site	chr22:29118443-29118444:+		[2]
Sequence	GTTTGGGCTGCTGTAACAAAATACCATAGAGTGGGTGGCTT
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: RNA-editing_site_91720
mod ID: A2ISITE011158		Click to Show/Hide the Full List
mod site	chr22:29118557-29118558:+		[2]
Sequence	CTGGTGAGGCCTCTCTTCCTAGTTTGCTGAGGGCTACCTTC
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000407188.5
External Link	RMBase: RNA-editing_site_91721
mod ID: A2ISITE011159		Click to Show/Hide the Full List
mod site	chr22:29118619-29118620:+		[2]
Sequence	CTCTGGTCTCTTCCTCATATAAGGGCAGTGATTCCATCATG
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000407188.5
External Link	RMBase: RNA-editing_site_91722
mod ID: A2ISITE011160		Click to Show/Hide the Full List
mod site	chr22:29118620-29118621:+		[2]
Sequence	TCTGGTCTCTTCCTCATATAAGGGCAGTGATTCCATCATGG
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000407188.5
External Link	RMBase: RNA-editing_site_91723
mod ID: A2ISITE011161		Click to Show/Hide the Full List
mod site	chr22:29118656-29118657:+		[2]
Sequence	CATGGGGGCTCAGCCATCATAATCTCATCTAAACCTAATTA
Transcript ID List	ENST00000407188.5; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: RNA-editing_site_91724
mod ID: A2ISITE011162		Click to Show/Hide the Full List
mod site	chr22:29120815-29120816:+		[2]
Sequence	CTCCTGACCTCCAGAACTGAAAGATAATAAATTTATGTTAT
Transcript ID List	ENST00000400335.8; rmsk_5268271; ENST00000327813.9; ENST00000407188.5
External Link	RMBase: RNA-editing_site_91725

5-methylcytidine (m5C)

In total 4 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002888		Click to Show/Hide the Full List
mod site	chr22:29142527-29142528:+
Sequence	CTTCTCTATTTTTGTCCACACACAAATCAGTTTCTCCTGAT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m5C_site_30581
mod ID: M5CSITE002889		Click to Show/Hide the Full List
mod site	chr22:29145752-29145753:+
Sequence	GAGGCCTCTCTGGGCGTGAGCGAGGAAACCAGGCTGCTCTA
Cell/Tissue List	muscle; T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m5C_site_30582
mod ID: M5CSITE002890		Click to Show/Hide the Full List
mod site	chr22:29145802-29145803:+
Sequence	GAGTGGGCTCTGGCTCAAGACTCCAATCGGCCAGAAGCCCA
Cell/Tissue List	frontalcortex; HEK293T; muscle; testis; T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m5C_site_30583
mod ID: M5CSITE002891		Click to Show/Hide the Full List
mod site	chr22:29145966-29145967:+
Sequence	CTCAGGATCTGCCTGCAGCCCAGCCAGGCCATCACCCAGCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m5C_site_30584

N6-methyladenosine (m6A)

In total 71 m6A sequence/site(s) in this target gene
mod ID: M6ASITE057138		Click to Show/Hide the Full List
mod site	chr22:29094292-29094293:+		[3]
Sequence	ATGGTGCGGATTATAGGGGAACACAGAACTGGACAGCACTA
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000407188.5; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560185
mod ID: M6ASITE057139		Click to Show/Hide the Full List
mod site	chr22:29094299-29094300:+		[3]
Sequence	GGATTATAGGGGAACACAGAACTGGACAGCACTACAAGGCG
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: m6A_site_560186
mod ID: M6ASITE057140		Click to Show/Hide the Full List
mod site	chr22:29094304-29094305:+		[3]
Sequence	ATAGGGGAACACAGAACTGGACAGCACTACAAGGCGGGAAG
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: m6A_site_560187
mod ID: M6ASITE057141		Click to Show/Hide the Full List
mod site	chr22:29094312-29094313:+		[4]
Sequence	ACACAGAACTGGACAGCACTACAAGGCGGGAAGCCATGTCT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000407188.5; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560188
mod ID: M6ASITE057142		Click to Show/Hide the Full List
mod site	chr22:29094346-29094347:+		[3]
Sequence	CATGTCTGTTTTGGAACGAGACTTTCCAGCATCCATACAAC
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000407188.5
External Link	RMBase: m6A_site_560189
mod ID: M6ASITE057143		Click to Show/Hide the Full List
mod site	chr22:29094362-29094363:+		[4]
Sequence	CGAGACTTTCCAGCATCCATACAACACTCTGAAATACCCCA
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000407188.5; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560190
mod ID: M6ASITE057144		Click to Show/Hide the Full List
mod site	chr22:29094407-29094408:+		[4]
Sequence	GGAGGGGGGCCTGGGTGAGCACAACTATTGCAGGTAAGATG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000407188.5
External Link	RMBase: m6A_site_560191
mod ID: M6ASITE057145		Click to Show/Hide the Full List
mod site	chr22:29121377-29121378:+		[4]
Sequence	GCCTGGAAACCTTGGCTGCTACAAGGATCATGGAAACCCAC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000407188.5; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560192
mod ID: M6ASITE057146		Click to Show/Hide the Full List
mod site	chr22:29125302-29125303:+		[4]
Sequence	CTATGCTTGCTTCTGTGGAAACAATCCTGATTACTGGAAGT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000453585.1; ENST00000327813.9; ENST00000474001.1
External Link	RMBase: m6A_site_560193
mod ID: M6ASITE057147		Click to Show/Hide the Full List
mod site	chr22:29125371-29125372:+		[4]
Sequence	CAGCGTCTGCTTCGGGGATCACACCCAACCCTGTGGTGGCG
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000474001.1; ENST00000453585.1; ENST00000327813.9
External Link	RMBase: m6A_site_560194
mod ID: M6ASITE057148		Click to Show/Hide the Full List
mod site	chr22:29137365-29137366:+		[3]
Sequence	CGTGGGCGCCTGCGGTGGGAACTACTCAGCCATGTCTTCTG
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000453585.1; ENST00000474001.1; ENST00000327813.9
External Link	RMBase: m6A_site_560195
mod ID: M6ASITE057149		Click to Show/Hide the Full List
mod site	chr22:29137410-29137411:+		[4]
Sequence	CTATTCCCCTGACTTCCCCGACACCTATGCCACGGGGAGGG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000407188.5; ENST00000453585.1; ENST00000327813.9; ENST00000400335.8; ENST00000474001.1
External Link	RMBase: m6A_site_560196
mod ID: M6ASITE057150		Click to Show/Hide the Full List
mod site	chr22:29137442-29137443:+		[3]
Sequence	CGGGGAGGGTCTGCTACTGGACCATCCGGGTTCCGGGGGCC
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000474001.1; ENST00000453585.1; ENST00000327813.9
External Link	RMBase: m6A_site_560197
mod ID: M6ASITE057151		Click to Show/Hide the Full List
mod site	chr22:29137467-29137468:+		[4]
Sequence	CCGGGTTCCGGGGGCCTCCCACATCCACTTCAGCTTCCCCC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000453585.1; ENST00000400335.8; ENST00000474001.1; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: m6A_site_560198
mod ID: M6ASITE057152		Click to Show/Hide the Full List
mod site	chr22:29137503-29137504:+		[3]
Sequence	CCCCCTATTTGACATCAGGGACTCGGCGGACATGGTGGAGC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000474001.1; ENST00000453585.1; ENST00000400335.8; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: m6A_site_560199
mod ID: M6ASITE057153		Click to Show/Hide the Full List
mod site	chr22:29137512-29137513:+		[3]
Sequence	TGACATCAGGGACTCGGCGGACATGGTGGAGCTTCTGGATG
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000453585.1; ENST00000327813.9; ENST00000407188.5; ENST00000400335.8; ENST00000474001.1
External Link	RMBase: m6A_site_560200
mod ID: M6ASITE057154		Click to Show/Hide the Full List
mod site	chr22:29137536-29137537:+		[4]
Sequence	GGTGGAGCTTCTGGATGGCTACACCCACCGTGTCCTAGCCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000453585.1; ENST00000327813.9; ENST00000407188.5; ENST00000474001.1; ENST00000400335.8
External Link	RMBase: m6A_site_560201
mod ID: M6ASITE057155		Click to Show/Hide the Full List
mod site	chr22:29137605-29137606:+		[3]
Sequence	GTCCTTCAACGTCTCTCTGGACTTCGTCATCTTGTATTTCT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000474001.1; ENST00000327813.9; ENST00000453585.1; ENST00000407188.5; ENST00000400335.8
External Link	RMBase: m6A_site_560202
mod ID: M6ASITE057156		Click to Show/Hide the Full List
mod site	chr22:29138772-29138773:+		[3]
Sequence	GCCCCAGCCACCCACCTCAGACTGTCCCAGGTAGCAATTCC
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: m6A_site_560203
mod ID: M6ASITE057157		Click to Show/Hide the Full List
mod site	chr22:29141969-29141970:+		[3]
Sequence	TCGTGTTCCTGCTTCAGGGGACCTTAGGGATTGTCATCAAC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400335.8; ENST00000407188.5; ENST00000327813.9
External Link	RMBase: m6A_site_560204
mod ID: M6ASITE057158		Click to Show/Hide the Full List
mod site	chr22:29141995-29141996:+		[3]
Sequence	GGGATTGTCATCAACCAGGGACTTCGGGGGAAATCTGGAGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000407188.5; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560205
mod ID: M6ASITE057159		Click to Show/Hide the Full List
mod site	chr22:29142060-29142061:+		[3]
Sequence	ATTTCCATCTTTAAGAAGAAACTCAAGGGTCAGAGTCAACA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8; ENST00000407188.5
External Link	RMBase: m6A_site_560206
mod ID: M6ASITE057160		Click to Show/Hide the Full List
mod site	chr22:29142107-29142108:+		[5]
Sequence	CCGCAATCCCCTTGTGAGTGACTAAAAACCCCACTGTGCCT
Motif Score	3.28175
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9; ENST00000407188.5
External Link	RMBase: m6A_site_560207
mod ID: M6ASITE057161		Click to Show/Hide the Full List
mod site	chr22:29142114-29142115:+		[3]
Sequence	CCCCTTGTGAGTGACTAAAAACCCCACTGTGCCTAGGACTT
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; GM12878; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560208
mod ID: M6ASITE057162		Click to Show/Hide the Full List
mod site	chr22:29142131-29142132:+		[3]
Sequence	AAAACCCCACTGTGCCTAGGACTTGAGGTCCCTCTTTGAGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; GM12878; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560209
mod ID: M6ASITE057163		Click to Show/Hide the Full List
mod site	chr22:29142193-29142194:+		[6]
Sequence	TCTCCTGTGGTTCTTCTCTGACAGACTCTTCCCCTCCTCTC
Motif Score	2.859755952
Cell/Tissue List	kidney; HEK293T
Seq Type List	m6A-REF-seq; DART-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560210
mod ID: M6ASITE057164		Click to Show/Hide the Full List
mod site	chr22:29142197-29142198:+		[3]
Sequence	CTGTGGTTCTTCTCTGACAGACTCTTCCCCTCCTCTCCCTC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; GM12878; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560211
mod ID: M6ASITE057165		Click to Show/Hide the Full List
mod site	chr22:29142239-29142240:+		[3]
Sequence	GCCTCGGCCTCTTCGGGGAAACCCTCCTCCTACAGACTAGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; GM12878; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560212
mod ID: M6ASITE057166		Click to Show/Hide the Full List
mod site	chr22:29142254-29142255:+		[3]
Sequence	GGGAAACCCTCCTCCTACAGACTAGGAAGAGGCACCCTGCT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; GM12878; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400335.8; ENST00000479755.1; ENST00000327813.9
External Link	RMBase: m6A_site_560213
mod ID: M6ASITE057167		Click to Show/Hide the Full List
mod site	chr22:29142319-29142320:+		[7]
Sequence	CCTCCTGCTTCATCGATTGCACTTAGGAGAGAGACTCAAAG
Motif Score	3.252583333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560214
mod ID: M6ASITE057168		Click to Show/Hide the Full List
mod site	chr22:29142332-29142333:+		[3]
Sequence	CGATTGCACTTAGGAGAGAGACTCAAAGCCCTGGGGCCCGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; GM12878; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560215
mod ID: M6ASITE057169		Click to Show/Hide the Full List
mod site	chr22:29142400-29142401:+		[3]
Sequence	CTAGCAGTGGGGGTGTCAGGACAGTGAGGCTGAGATGACAG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; kidney; A549; U2OS; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-REF-seq
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560216
mod ID: M6ASITE057170		Click to Show/Hide the Full List
mod site	chr22:29142562-29142563:+		[8]
Sequence	CCTGATCTTTATGTCTTGGAACAGGGCCAGACAGGGAGAAC
Motif Score	2.951386905
Cell/Tissue List	HEK293T; HEK293A-TOA
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560217
mod ID: M6ASITE057171		Click to Show/Hide the Full List
mod site	chr22:29142572-29142573:+		[8]
Sequence	ATGTCTTGGAACAGGGCCAGACAGGGAGAACTCTCAGGTAC
Motif Score	2.897386905
Cell/Tissue List	HEK293T; HEK293A-TOA
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000479755.1; ENST00000327813.9
External Link	RMBase: m6A_site_560218
mod ID: M6ASITE057172		Click to Show/Hide the Full List
mod site	chr22:29142581-29142582:+		[8]
Sequence	AACAGGGCCAGACAGGGAGAACTCTCAGGTACTCTTGGGAG
Motif Score	3.373380952
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560219
mod ID: M6ASITE057173		Click to Show/Hide the Full List
mod site	chr22:29142612-29142613:+		[7]
Sequence	CTCTTGGGAGTTGGTCCCATACAAGTGCGGACTCCTGGACA
Motif Score	2.110482143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560220
mod ID: M6ASITE057174		Click to Show/Hide the Full List
mod site	chr22:29142622-29142623:+		[8]
Sequence	TTGGTCCCATACAAGTGCGGACTCCTGGACATTAGCGAGGT
Motif Score	4.065041667
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560221
mod ID: M6ASITE057175		Click to Show/Hide the Full List
mod site	chr22:29142630-29142631:+		[8]
Sequence	ATACAAGTGCGGACTCCTGGACATTAGCGAGGTGTAAAGAG
Motif Score	3.643047619
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560222
mod ID: M6ASITE057176		Click to Show/Hide the Full List
mod site	chr22:29142696-29142697:+		[8]
Sequence	CTTTGCTCTCCAGATGCTGGACTAGGGTGGGCCTCCTTCAG
Motif Score	4.065041667
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560223
mod ID: M6ASITE057177		Click to Show/Hide the Full List
mod site	chr22:29142950-29142951:+		[3]
Sequence	CCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTG
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; rmsk_5268323; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560224
mod ID: M6ASITE057178		Click to Show/Hide the Full List
mod site	chr22:29142973-29142974:+		[3]
Sequence	AGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATA
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1; rmsk_5268323
External Link	RMBase: m6A_site_560225
mod ID: M6ASITE057179		Click to Show/Hide the Full List
mod site	chr22:29143038-29143039:+		[7]
Sequence	AGGCGCCTGTAATCCCAGCTACTCAGAAGGCTGAGACAGAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1; rmsk_5268323
External Link	RMBase: m6A_site_560226
mod ID: M6ASITE057180		Click to Show/Hide the Full List
mod site	chr22:29143754-29143755:+		[3]
Sequence	CTGTCTCAAAAAAAAAAAAAACACTCCAAGGGCCATCCGTG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8; rmsk_5268324
External Link	RMBase: m6A_site_560227
mod ID: M6ASITE057181		Click to Show/Hide the Full List
mod site	chr22:29143796-29143797:+		[9]
Sequence	TCTCTGCCCCTCCTGTGGGGACCAAGTGGGGTTAGGAATGG
Motif Score	3.622404762
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560228
mod ID: M6ASITE057182		Click to Show/Hide the Full List
mod site	chr22:29144241-29144242:+		[3]
Sequence	CTCCTACTGAGGTTCTGGAAACACCTCTGCACCTGCCGCCC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560229
mod ID: M6ASITE057183		Click to Show/Hide the Full List
mod site	chr22:29144410-29144411:+		[3]
Sequence	CACAGGCAGGCAGGGGCAGGACTGCCACCCCAGGCCCCGTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; MM6; Jurkat; peripheral-blood; GSC-11; HEK293T; iSLK; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560230
mod ID: M6ASITE057184		Click to Show/Hide the Full List
mod site	chr22:29144539-29144540:+		[3]
Sequence	GAGGCCTGTCACACAGGAGGACCGCTGGAAACATACCAACA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560231
mod ID: M6ASITE057185		Click to Show/Hide the Full List
mod site	chr22:29144549-29144550:+		[3]
Sequence	ACACAGGAGGACCGCTGGAAACATACCAACACGTGCAGTCT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560232
mod ID: M6ASITE057186		Click to Show/Hide the Full List
mod site	chr22:29145088-29145089:+
Sequence	CTGCCGCAGCCTGGCTATGGACTCAGTTAGAACCAGGTAGA
Motif Score	4.065041667
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560233
mod ID: M6ASITE057187		Click to Show/Hide the Full List
mod site	chr22:29145099-29145100:+		[3]
Sequence	TGGCTATGGACTCAGTTAGAACCAGGTAGAAAGTCAGCGAC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560234
mod ID: M6ASITE057188		Click to Show/Hide the Full List
mod site	chr22:29145150-29145151:+		[3]
Sequence	AGGCCACTGCGGCTAGGTAAACACCTGAGAAAGAAACTGCT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560235
mod ID: M6ASITE057189		Click to Show/Hide the Full List
mod site	chr22:29145165-29145166:+		[3]
Sequence	GGTAAACACCTGAGAAAGAAACTGCTCCAGAAGAGATGACG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560236
mod ID: M6ASITE057190		Click to Show/Hide the Full List
mod site	chr22:29145221-29145222:+		[3]
Sequence	ATGGAGGAGGTGGCACTTGAACTTTTAGGAAACTCCTTAGA
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000479755.1; ENST00000327813.9; ENST00000400335.8
External Link	RMBase: m6A_site_560237
mod ID: M6ASITE057191		Click to Show/Hide the Full List
mod site	chr22:29145232-29145233:+		[3]
Sequence	GGCACTTGAACTTTTAGGAAACTCCTTAGATGAGATAAAGT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560238
mod ID: M6ASITE057192		Click to Show/Hide the Full List
mod site	chr22:29145302-29145303:+		[3]
Sequence	CCCTGGGAAAGTCAGTCAGAACCCATGGCAGAAGACTGCAG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560239
mod ID: M6ASITE057193		Click to Show/Hide the Full List
mod site	chr22:29145316-29145317:+		[3]
Sequence	GTCAGAACCCATGGCAGAAGACTGCAGGAGAGGCAGGGGAG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; Huh7; Jurkat; peripheral-blood; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560240
mod ID: M6ASITE057194		Click to Show/Hide the Full List
mod site	chr22:29145348-29145349:+		[3]
Sequence	GCAGGGGAGGGGCTTCGGGGACCACTGTGGACAGAGCTCTG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; Jurkat; peripheral-blood; GSC-11; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560241
mod ID: M6ASITE057195		Click to Show/Hide the Full List
mod site	chr22:29145358-29145359:+		[3]
Sequence	GGCTTCGGGGACCACTGTGGACAGAGCTCTGAAAGCACCCT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; Jurkat; peripheral-blood; GSC-11; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560242
mod ID: M6ASITE057196		Click to Show/Hide the Full List
mod site	chr22:29145624-29145625:+		[7]
Sequence	AGAAGGCAGGCGGGAGGCACACGGTGCCCTGTTCTTCCCCG
Motif Score	2.058863095
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560243
mod ID: M6ASITE057197		Click to Show/Hide the Full List
mod site	chr22:29145724-29145725:+		[8]
Sequence	GCCCTGTCCCCCACGTCAGGACAGGCTTGAGGCCTCTCTGG
Motif Score	3.643047619
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560244
mod ID: M6ASITE057198		Click to Show/Hide the Full List
mod site	chr22:29145759-29145760:+		[3]
Sequence	CTCTGGGCGTGAGCGAGGAAACCAGGCTGCTCTAACTTCTG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560245
mod ID: M6ASITE057199		Click to Show/Hide the Full List
mod site	chr22:29145801-29145802:+		[3]
Sequence	AGAGTGGGCTCTGGCTCAAGACTCCAATCGGCCAGAAGCCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560246
mod ID: M6ASITE057200		Click to Show/Hide the Full List
mod site	chr22:29146359-29146360:+		[3]
Sequence	GCTTCACCCTCTGCCTGCAGACCCCTGGTGGGCACATCTCA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000400335.8; ENST00000479755.1
External Link	RMBase: m6A_site_560247
mod ID: M6ASITE057201		Click to Show/Hide the Full List
mod site	chr22:29146474-29146475:+		[3]
Sequence	CAGAAAGGAAGGGTCTTTAGACACAAAGACTGGAGGCCCTT
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: m6A_site_560248
mod ID: M6ASITE057202		Click to Show/Hide the Full List
mod site	chr22:29146482-29146483:+		[3]
Sequence	AAGGGTCTTTAGACACAAAGACTGGAGGCCCTTCCCCGCCC
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560249
mod ID: M6ASITE057203		Click to Show/Hide the Full List
mod site	chr22:29146541-29146542:+		[3]
Sequence	TGGGTCTCATGCACGTCAAGACCTTCCCACATCCAAACTCA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000479755.1; ENST00000400335.8; ENST00000327813.9
External Link	RMBase: m6A_site_560250
mod ID: M6ASITE057204		Click to Show/Hide the Full List
mod site	chr22:29146557-29146558:+		[3]
Sequence	CAAGACCTTCCCACATCCAAACTCAGCTTCCAGCAGGGATT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000400335.8; ENST00000479755.1; ENST00000327813.9
External Link	RMBase: m6A_site_560251
mod ID: M6ASITE057205		Click to Show/Hide the Full List
mod site	chr22:29146581-29146582:+		[7]
Sequence	AGCTTCCAGCAGGGATTTTGACTTTGGATGACAAGGCTTTA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000400335.8; ENST00000327813.9; ENST00000479755.1
External Link	RMBase: m6A_site_560252
mod ID: M6ASITE057206		Click to Show/Hide the Full List
mod site	chr22:29146681-29146682:+		[7]
Sequence	AAAATATAAGATGAAGTGTGACGCACTGTATACAATTTAAT
Motif Score	2.833690476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000400335.8; ENST00000479755.1; ENST00000327813.9
External Link	RMBase: m6A_site_560253
mod ID: M6ASITE057207		Click to Show/Hide the Full List
mod site	chr22:29167540-29167541:+		[10]
Sequence	ACACAGCAAGCAACCACAAAACCAGAGCGGAAGGAGGGACT
Motif Score	2.185083333
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000327813.9
External Link	RMBase: m6A_site_560254
mod ID: M6ASITE057208		Click to Show/Hide the Full List
mod site	chr22:29167558-29167559:+		[10]
Sequence	AAACCAGAGCGGAAGGAGGGACTTCCCACCGGCATCCGGCC
Motif Score	4.065041667
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000327813.9
External Link	RMBase: m6A_site_560255

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000179		Click to Show/Hide the Full List
mod site	chr22:29142644-29142645:+		[11]
Sequence	TCCTGGACATTAGCGAGGTGTAAAGAGGGCAGTGTCTGTGC
Transcript ID List	ENST00000327813.9; ENST00000479755.1; ENST00000400335.8
External Link	RMBase: Pseudo_site_3425

Ref 1	Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity. Nat Commun. 2020 Jun 1;11(1):2739. doi: 10.1038/s41467-020-16602-0.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 6	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 7	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 8	The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003.
Ref 9	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 10	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 11	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map