m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01613)
Target Name LINE-1 retrotransposable element ORF1 protein (LINE1)
Synonyms
L1ORF1p; LINE1 retrotransposable element 1; LRE1
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Gene Name LINE1
Chromosomal Location 22q12.1
Function
Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.
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Gene ID 151626
Uniprot ID
LORF1_HUMAN
HGNC ID
HGNC:6686
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Histone modification
m6A Regulator: YTH domain-containing protein 1 (YTHDC1)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03094
 Crosstalk Info 
Epigenetic Regulator Histone-lysine N-methyltransferase SETDB1 (SETDB1)
Regulated Target Histone H3 lysine 9 trimethylation (H3K9me3)
Crosstalk relationship m6A → Histone modification
References
Ref 1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1636).