m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01442)
Target Name Beta-1,4-glucuronyltransferase 1 (B3GNT6)
Synonyms
EC 2.4.1.-; I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
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Gene Name B3GNT6
Chromosomal Location 11q13.2
Family Glycosyltransferase 49 family
Function
Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1) (PubMed:19587235, PubMed:23359570, PubMed:25279699, PubMed:25279697). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1) (By similarity).
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Gene ID 11041
Uniprot ID
B4GA1_HUMAN
HGNC ID
HGNC:15685
KEGG ID
hsa:11041
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Histone modification
m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03478
 Crosstalk Info 
Epigenetic Regulator Histone acetyltransferase p300 (P300)
Regulated Target Histone H3 lysine 18 lactylation (H3K18la)
Crosstalk relationship Histone modification → m6A
Disease Pancreatic cancer
 Disease Info 
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01442)
Beta-1,4-glucuronyltransferase 1 (B3GNT6)
N1-methyladenosine (m1A)
In total 1 m6A sequence/site(s) in this target gene
mod ID: M1ASITE000022 Click to Show/Hide the Full List
mod site chr11:66345901-66345902:- [2]
Sequence GATATGGGGTGCTGGGATCGATTCCTAGCTTTACCACTAAC
Cell/Tissue List HEK293T
Seq Type List m1A-seq
Transcript ID List rmsk_3571573; ENST00000311181.5
External Link RMBase: m1A_site_204
5-methylcytidine (m5C)
In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE005223 Click to Show/Hide the Full List
mod site chr11:66345526-66345527:- [3]
Sequence TTGAACAGAAGCCTAAAATTCCTGGTTCTCTCAGGGCTTCG
Cell/Tissue List frontalcortex; heart; liver; HeLa; T24
Seq Type List Bisulfite-seq; m5C-RIP-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m5C_site_8067
N6-methyladenosine (m6A)
In total 27 m6A sequence/site(s) in this target gene
mod ID: M6ASITE007250 Click to Show/Hide the Full List
mod site chr11:66345404-66345405:- [4]
Sequence TGGGTATGTGCCTACCGATGACAATGTGTAAATAAATGCGT
Motif Score 2.859755952
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149782
mod ID: M6ASITE007251 Click to Show/Hide the Full List
mod site chr11:66345542-66345543:- [5]
Sequence ATTTAGTTCTTAGCTCTTGAACAGAAGCCTAAAATTCCTGG
Motif Score 2.951386905
Cell/Tissue List HeLa; HEK293T; U2OS; hNPCs; fibroblasts; A549; MM6; Huh7; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149783
mod ID: M6ASITE007252 Click to Show/Hide the Full List
mod site chr11:66345595-66345596:- [5]
Sequence CTGAATACTTAATGAAATGGACTTTTTGGAAAGAAATCAGA
Motif Score 4.065041667
Cell/Tissue List HeLa; HEK293T; U2OS; hNPCs; hESCs; fibroblasts; A549; MM6; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149784
mod ID: M6ASITE007253 Click to Show/Hide the Full List
mod site chr11:66345609-66345610:- [4]
Sequence TGGAGCTAAGAAGTCTGAATACTTAATGAAATGGACTTTTT
Motif Score 2.53247619
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149785
mod ID: M6ASITE007254 Click to Show/Hide the Full List
mod site chr11:66345673-66345674:- [4]
Sequence TATTATTATTGTTATTATTAACAATCTTGGGTGGGTAGTAG
Motif Score 2.168095238
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149786
mod ID: M6ASITE007255 Click to Show/Hide the Full List
mod site chr11:66345734-66345735:- [4]
Sequence AAACATTCTGTAAGCTTCGTACAAATGTGAAGTATTAATAT
Motif Score 2.856142857
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000311181.5; rmsk_3571573
External Link RMBase: m6A_site_149787
mod ID: M6ASITE007256 Click to Show/Hide the Full List
mod site chr11:66345752-66345753:- [5]
Sequence ATGAGATGCTATATGTGAAAACATTCTGTAAGCTTCGTACA
Motif Score 2.20572619
Cell/Tissue List HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq; DART-seq; MAZTER-seq
Transcript ID List ENST00000311181.5; rmsk_3571573
External Link RMBase: m6A_site_149788
mod ID: M6ASITE007257 Click to Show/Hide the Full List
mod site chr11:66345789-66345790:- [5]
Sequence GAGAATACCTACCTCACGGAACTGTTGGGAGGCTCAGATGA
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000311181.5; rmsk_3571573
External Link RMBase: m6A_site_149789
mod ID: M6ASITE007258 Click to Show/Hide the Full List
mod site chr11:66345851-66345852:- [4]
Sequence GGCCTTGAGTAAATCCCGTTACCTCTCTGAGCCTCGGTTAC
Motif Score 2.052208333
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000311181.5; rmsk_3571573
External Link RMBase: m6A_site_149790
mod ID: M6ASITE007259 Click to Show/Hide the Full List
mod site chr11:66345882-66345883:- [4]
Sequence GATTCCTAGCTTTACCACTAACTAGCTGTGTGGCCTTGAGT
Motif Score 2.590089286
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List rmsk_3571573; ENST00000311181.5
External Link RMBase: m6A_site_149791
mod ID: M6ASITE007260 Click to Show/Hide the Full List
mod site chr11:66345926-66345927:- [5]
Sequence CTGTGGTGTTGAAACACTGGACTTGGATATGGGGTGCTGGG
Motif Score 4.065041667
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000311181.5; rmsk_3571573
External Link RMBase: m6A_site_149792
mod ID: M6ASITE007261 Click to Show/Hide the Full List
mod site chr11:66345931-66345932:- [4]
Sequence GGTAGCTGTGGTGTTGAAACACTGGACTTGGATATGGGGTG
Motif Score 2.506922619
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List rmsk_3571573; ENST00000311181.5
External Link RMBase: m6A_site_149793
mod ID: M6ASITE007262 Click to Show/Hide the Full List
mod site chr11:66345933-66345934:- [5]
Sequence GAGGTAGCTGTGGTGTTGAAACACTGGACTTGGATATGGGG
Motif Score 2.20572619
Cell/Tissue List HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List m6A-seq; MeRIP-seq; DART-seq; MAZTER-seq
Transcript ID List rmsk_3571573; ENST00000311181.5
External Link RMBase: m6A_site_149794
mod ID: M6ASITE007263 Click to Show/Hide the Full List
mod site chr11:66345956-66345957:- [6]
Sequence AAGAAATGTCGCTCCACTTTACAGAGGTAGCTGTGGTGTTG
Motif Score 2.07285119
Cell/Tissue List brain; kidney
Seq Type List m6A-REF-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149795
mod ID: M6ASITE007264 Click to Show/Hide the Full List
mod site chr11:66346057-66346058:- [4]
Sequence AAGTACCCCAACTCTCCCCGACGCTGCTGAGCCCTTCCCTC
Motif Score 2.839505952
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149796
mod ID: M6ASITE007265 Click to Show/Hide the Full List
mod site chr11:66346093-66346094:- [7]
Sequence ATCCTATATCGCCAGTTCAAACAGGAGTTGAAGGCCAAGTA
Motif Score 2.20572619
Cell/Tissue List HepG2; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149797
mod ID: M6ASITE007266 Click to Show/Hide the Full List
mod site chr11:66346577-66346578:- [5]
Sequence CTACGTGGTACCTTGGCAGGACCCCTGGGAGCCATTCTACG
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; A549; iSLK; MSC
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149798
mod ID: M6ASITE007267 Click to Show/Hide the Full List
mod site chr11:66346727-66346728:- [4]
Sequence CCGCATGCCCATGAACAAAAACGAGCTGGTGCAGCTCTACC
Motif Score 2.179660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149799
mod ID: M6ASITE007268 Click to Show/Hide the Full List
mod site chr11:66346733-66346734:- [5]
Sequence AGCCCGCCGCATGCCCATGAACAAAAACGAGCTGGTGCAGC
Motif Score 2.951386905
Cell/Tissue List HeLa; HepG2; HEK293T; brain; A549; hESC-HEK293T; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq; m6A-REF-seq; MAZTER-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149800
mod ID: M6ASITE007269 Click to Show/Hide the Full List
mod site chr11:66346859-66346860:- [5]
Sequence TGCCCTGGTGATCGATGTGGACATGGTGCCCAGCGAGGGGC
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2; HEK293T; A549; hESC-HEK293T; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149801
mod ID: M6ASITE007270 Click to Show/Hide the Full List
mod site chr11:66346985-66346986:- [8]
Sequence GTCCTGCCAGGAGGTCTTTGACAAGCTAGCCAGGGTGGCCC
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149802
mod ID: M6ASITE007271 Click to Show/Hide the Full List
mod site chr11:66347234-66347235:- [5]
Sequence GGCCACGCACGCCAGCGTGGACAACCTGCTGCACCTGTCGG
Motif Score 3.643047619
Cell/Tissue List HeLa; A549; MM6; Jurkat; GSC-11; HEK293T; HEK293A-TOA; iSLK; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149803
mod ID: M6ASITE007272 Click to Show/Hide the Full List
mod site chr11:66347273-66347274:- [5]
Sequence CCTGCTGAAGACCACCATGGACCCCAACGATGTGATCCTGG
Motif Score 3.622404762
Cell/Tissue List HeLa; A549; MM6; Jurkat; GSC-11; HEK293T; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149804
mod ID: M6ASITE007273 Click to Show/Hide the Full List
mod site chr11:66347283-66347284:- [5]
Sequence TCTACAGGGGCCTGCTGAAGACCACCATGGACCCCAACGAT
Motif Score 2.876744048
Cell/Tissue List HeLa; A549; MM6; Jurkat; GSC-11; HEK293T; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149805
mod ID: M6ASITE007274 Click to Show/Hide the Full List
mod site chr11:66347375-66347376:- [5]
Sequence CCCGTCCCCACGGTCCGTGGACCAGGTCAAGGCGCAGCTCC
Motif Score 3.622404762
Cell/Tissue List HeLa; A549; MM6; GSC-11; HEK293T; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149806
mod ID: M6ASITE007275 Click to Show/Hide the Full List
mod site chr11:66347417-66347418:- [5]
Sequence GCACGGGCAGGAGGAGCAAGACCAATATTTTGAGTTCTTTC
Motif Score 2.876744048
Cell/Tissue List HeLa; GSC-11; HEK293T; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149807
mod ID: M6ASITE007276 Click to Show/Hide the Full List
mod site chr11:66347440-66347441:- [5]
Sequence TACCTGTCGCTGCTGTCCGGACTGCACGGGCAGGAGGAGCA
Motif Score 4.065041667
Cell/Tissue List HeLa; Jurkat; GSC-11; HEK293T; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311181.5
External Link RMBase: m6A_site_149808