m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01383)

Target Name	Histone deacetylase 9 (HDAC9)
Synonyms	HD9; EC 3.5.1.98; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; MEF2-interacting transcription repressor MITR Click to Show/Hide
Gene Name	HDAC9
Chromosomal Location	7p21.1
Family	Histone deacetylase family, HD type 2 subfamily
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. Click to Show/Hide
Gene ID	9734
Uniprot ID	HDAC9_HUMAN
HGNC ID	HGNC:14065
KEGG ID	hsa:9734

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03187		Crosstalk Info
Epigenetic Regulator	Histone deacetylase 9 (HDAC9)
Regulated Target	Histone H4 lysine 12 acetylation (H4K12ac)
Crosstalk relationship	m6A → Histone modification
Disease	Acute laryngitis or tracheitis	Disease Info

m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03188		Crosstalk Info
Epigenetic Regulator	Histone deacetylase 9 (HDAC9)
Regulated Target	Histone H4 lysine 12 acetylation (H4K12ac)
Crosstalk relationship	m6A → Histone modification
Disease	Acute laryngitis or tracheitis	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01383)

Histone deacetylase 9 (HDAC9)

Adenosine-to-Inosine editing (A-to-I)

In total 12 m6A sequence/site(s) in this target gene
mod ID: A2ISITE001885		Click to Show/Hide the Full List
mod site	chr7:18296708-18296709:+		[2]
Sequence	ATAAAACAAACTCAATGGCTATTTGAGAAATGCAGACACAT
Transcript ID List	ENST00000433709.6; ENST00000461159.6; ENST00000417496.6; ENST00000413509.6; ENST00000425071.5; ENST00000474742.1; ENST00000411993.1
External Link	RMBase: RNA-editing_site_121219
mod ID: A2ISITE001886		Click to Show/Hide the Full List
mod site	chr7:18297500-18297501:+		[2]
Sequence	CCAATCCATCCTACAGGCATAGACATTTAAAAACTCAAATT
Transcript ID List	ENST00000433709.6; ENST00000425071.5; ENST00000417496.6; ENST00000413509.6; ENST00000411993.1; ENST00000461159.6; ENST00000474742.1
External Link	RMBase: RNA-editing_site_121220
mod ID: A2ISITE001887		Click to Show/Hide the Full List
mod site	chr7:18297525-18297526:+		[2]
Sequence	TTTAAAAACTCAAATTTCATACCTTGTTTGGGGATACATAA
Transcript ID List	ENST00000461159.6; ENST00000411993.1; ENST00000413509.6; ENST00000425071.5; ENST00000417496.6; ENST00000474742.1; ENST00000433709.6
External Link	RMBase: RNA-editing_site_121221
mod ID: A2ISITE001888		Click to Show/Hide the Full List
mod site	chr7:18435645-18435646:+		[2]
Sequence	TGCAGGTTTGTTATGTAGGTAAATTGCATGTCTTGGGGGTT
Transcript ID List	ENST00000413509.6; ENST00000461159.6; ENST00000417496.6; ENST00000474742.1; ENST00000433709.6
External Link	RMBase: RNA-editing_site_121222
mod ID: A2ISITE001889		Click to Show/Hide the Full List
mod site	chr7:18547433-18547434:+		[3]
Sequence	TTTAGTGGAGACGGGGTTTCACCATGTTAGCCAGGACAGTC
Transcript ID List	ENST00000446646.1; ENST00000441542.6; ENST00000401921.5; ENST00000476135.5; ENST00000456174.6; ENST00000405010.7; ENST00000430454.5; ENST00000413509.6; ENST00000622668.4; ENST00000428307.6; ENST00000461159.6; ENST00000406451.8; ENST00000406072.5; ENST00000433709.6; ENST00000413380.5; ENST00000524023.1; ENST00000523867.5; ENST00000432645.6; ENST00000441986.5; ENST00000417496.6
External Link	RMBase: RNA-editing_site_121223
mod ID: A2ISITE001890		Click to Show/Hide the Full List
mod site	chr7:18547441-18547442:+		[3]
Sequence	AGACGGGGTTTCACCATGTTAGCCAGGACAGTCTTGATCTC
Transcript ID List	ENST00000406072.5; ENST00000428307.6; ENST00000524023.1; ENST00000413509.6; ENST00000523867.5; ENST00000441542.6; ENST00000430454.5; ENST00000441986.5; ENST00000432645.6; ENST00000401921.5; ENST00000405010.7; ENST00000461159.6; ENST00000476135.5; ENST00000413380.5; ENST00000406451.8; ENST00000456174.6; ENST00000433709.6; ENST00000446646.1; ENST00000622668.4; ENST00000417496.6
External Link	RMBase: RNA-editing_site_121224
mod ID: A2ISITE001891		Click to Show/Hide the Full List
mod site	chr7:18547450-18547451:+		[3]
Sequence	TTCACCATGTTAGCCAGGACAGTCTTGATCTCCTGACCTTG
Transcript ID List	ENST00000446646.1; ENST00000406451.8; ENST00000405010.7; ENST00000441986.5; ENST00000430454.5; ENST00000406072.5; ENST00000524023.1; ENST00000401921.5; ENST00000417496.6; ENST00000432645.6; ENST00000461159.6; ENST00000428307.6; ENST00000523867.5; ENST00000441542.6; ENST00000476135.5; ENST00000433709.6; ENST00000622668.4; ENST00000456174.6; ENST00000413509.6; ENST00000413380.5
External Link	RMBase: RNA-editing_site_121225
mod ID: A2ISITE001892		Click to Show/Hide the Full List
mod site	chr7:18547508-18547509:+		[3]
Sequence	CCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCC
Transcript ID List	ENST00000413380.5; ENST00000432645.6; ENST00000441986.5; ENST00000401921.5; ENST00000523867.5; ENST00000441542.6; ENST00000622668.4; ENST00000406451.8; ENST00000524023.1; ENST00000406072.5; ENST00000476135.5; ENST00000456174.6; ENST00000433709.6; ENST00000417496.6; ENST00000405010.7; ENST00000430454.5; ENST00000428307.6; ENST00000461159.6; ENST00000446646.1; ENST00000413509.6
External Link	RMBase: RNA-editing_site_121226
mod ID: A2ISITE001893		Click to Show/Hide the Full List
mod site	chr7:18824129-18824130:+		[2]
Sequence	AGAAGAGGTGGAGACACCAGAGCCCGCTTTGTGAGTGCTCA
Transcript ID List	ENST00000523867.5; ENST00000406451.8; ENST00000490851.5; ENST00000401921.5; ENST00000461159.6; ENST00000441542.6; ENST00000432645.6
External Link	RMBase: RNA-editing_site_121227
mod ID: A2ISITE001894		Click to Show/Hide the Full List
mod site	chr7:18824156-18824157:+		[2]
Sequence	TTTGTGAGTGCTCAGATGAAAGGCACTTGAGGGTGGCAGAG
Transcript ID List	ENST00000441542.6; ENST00000406451.8; ENST00000461159.6; ENST00000401921.5; ENST00000523867.5; ENST00000490851.5; ENST00000432645.6
External Link	RMBase: RNA-editing_site_121228
mod ID: A2ISITE001895		Click to Show/Hide the Full List
mod site	chr7:18824180-18824181:+		[2]
Sequence	ACTTGAGGGTGGCAGAGGGAAGACGGCTGTCTGCAAGCCGC
Transcript ID List	ENST00000432645.6; ENST00000523867.5; ENST00000441542.6; rmsk_2174843; ENST00000401921.5; ENST00000461159.6; ENST00000406451.8; ENST00000490851.5
External Link	RMBase: RNA-editing_site_121229
mod ID: A2ISITE001897		Click to Show/Hide the Full List
mod site	chr7:18824195-18824196:+		[2]
Sequence	AGGGAAGACGGCTGTCTGCAAGCCGCAAAGAGAGCTCTCAC
Transcript ID List	ENST00000523867.5; ENST00000441542.6; ENST00000432645.6; ENST00000401921.5; ENST00000490851.5; ENST00000461159.6; ENST00000406451.8; rmsk_2174843
External Link	RMBase: RNA-editing_site_121230

2'-O-Methylation (2'-O-Me)

In total 1 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000432		Click to Show/Hide the Full List
mod site	chr7:18702043-18702044:+		[4]
Sequence	AACTTCAGCTACTAACAGCAGTTGAACACTTTCTGCTAAGT
Cell/Tissue List	HEK293
Seq Type List	RiboMeth-seq
Transcript ID List	ENST00000441542.6; ENST00000406451.8; ENST00000401921.5; ENST00000461159.6; ENST00000432645.6; ENST00000523867.5
External Link	RMBase: Nm_site_6050

N6-methyladenosine (m6A)

In total 37 m6A sequence/site(s) in this target gene
mod ID: M6ASITE078836		Click to Show/Hide the Full List
mod site	chr7:18325548-18325549:+		[5]
Sequence	GTTGCCCAGGCTGGTATCAAACTCCAGTGATCAAGTGGTCC
Motif Score	2.627720238
Cell/Tissue List	Jurkat; peripheral-blood; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000461159.6; ENST00000411993.1; ENST00000417496.6; ENST00000433709.6; ENST00000425071.5; ENST00000413509.6; ENST00000474742.1
External Link	RMBase: m6A_site_749422
mod ID: M6ASITE078837		Click to Show/Hide the Full List
mod site	chr7:18325588-18325589:+		[5]
Sequence	CTCCTACCTCAGCCTCCCAAACAGGTGGGATTACAGACACA
Motif Score	2.20572619
Cell/Tissue List	Jurkat; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000461159.6; ENST00000425071.5; ENST00000411993.1; ENST00000433709.6; ENST00000474742.1; ENST00000417496.6; ENST00000413509.6
External Link	RMBase: m6A_site_749423
mod ID: M6ASITE078838		Click to Show/Hide the Full List
mod site	chr7:18495735-18495736:+		[6]
Sequence	GCCAACTTGAGCTGAGAGAGACTGAGAAAGGGGGAAGAGAG
Motif Score	3.319380952
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000413380.5; ENST00000417496.6; ENST00000430454.5; ENST00000461159.6; ENST00000474742.1; ENST00000433709.6; ENST00000413509.6
External Link	RMBase: m6A_site_749424
mod ID: M6ASITE078839		Click to Show/Hide the Full List
mod site	chr7:18495762-18495763:+		[6]
Sequence	AAGGGGGAAGAGAGGCACAGACACAGATAGGAGAAGGGCAC
Motif Score	2.897386905
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000417496.6; ENST00000476135.5; ENST00000433709.6; ENST00000622668.4; ENST00000413509.6; ENST00000461409.1; ENST00000405010.7; ENST00000428307.6; ENST00000474742.1; ENST00000461159.6; ENST00000406451.8; ENST00000430454.5; ENST00000413380.5
External Link	RMBase: m6A_site_749425
mod ID: M6ASITE078840		Click to Show/Hide the Full List
mod site	chr7:18495803-18495804:+		[6]
Sequence	CGGCTGGAGCCACTTGCAGGACTGAGGGTTTTTGCAACAAA
Motif Score	4.065041667
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000406451.8; ENST00000461409.1; ENST00000476135.5; ENST00000417496.6; ENST00000433709.6; ENST00000430454.5; ENST00000405010.7; ENST00000413509.6; ENST00000413380.5; ENST00000461159.6; ENST00000622668.4; ENST00000474742.1; ENST00000428307.6
External Link	RMBase: m6A_site_749426
mod ID: M6ASITE078841		Click to Show/Hide the Full List
mod site	chr7:18495824-18495825:+		[6]
Sequence	CTGAGGGTTTTTGCAACAAAACCCTAGCAGCCTGAAGAACT
Motif Score	2.185083333
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000461409.1; ENST00000622668.4; ENST00000417496.6; ENST00000476135.5; ENST00000406451.8; ENST00000433709.6; ENST00000428307.6; ENST00000461159.6; ENST00000405010.7; ENST00000413380.5; ENST00000413509.6; ENST00000430454.5; ENST00000474742.1
External Link	RMBase: m6A_site_749427
mod ID: M6ASITE078842		Click to Show/Hide the Full List
mod site	chr7:18495842-18495843:+		[6]
Sequence	AAACCCTAGCAGCCTGAAGAACTCTAAGCCAGGTTTAATTG
Motif Score	3.373380952
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000461159.6; ENST00000430454.5; ENST00000461409.1; ENST00000433709.6; ENST00000413509.6; ENST00000413380.5; ENST00000428307.6; ENST00000417496.6; ENST00000474742.1; ENST00000406451.8; ENST00000622668.4; ENST00000476135.5; ENST00000405010.7
External Link	RMBase: m6A_site_749428
mod ID: M6ASITE078843		Click to Show/Hide the Full List
mod site	chr7:18509335-18509336:+		[7]
Sequence	ATCAATGGGTAGGTGGGAGAACCAGGGGAAGACTGTCAGCT
Motif Score	2.930744048
Cell/Tissue List	fibroblasts
Seq Type List	m6A-seq
Transcript ID List	ENST00000432645.6; ENST00000417496.6; ENST00000461159.6; ENST00000456174.6; ENST00000476135.5; ENST00000430454.5; ENST00000523867.5; ENST00000524023.1; ENST00000406451.8; ENST00000441542.6; ENST00000428307.6; ENST00000446646.1; ENST00000622668.4; ENST00000406072.5; ENST00000433709.6; ENST00000413509.6; ENST00000405010.7; ENST00000413380.5; ENST00000471887.1; ENST00000401921.5; ENST00000441986.5
External Link	RMBase: m6A_site_749429
mod ID: M6ASITE078844		Click to Show/Hide the Full List
mod site	chr7:18509346-18509347:+		[7]
Sequence	GGTGGGAGAACCAGGGGAAGACTGTCAGCTACGATTTTCTC
Motif Score	3.319380952
Cell/Tissue List	fibroblasts
Seq Type List	m6A-seq
Transcript ID List	ENST00000401921.5; ENST00000406072.5; ENST00000430454.5; ENST00000446646.1; ENST00000476135.5; ENST00000441542.6; ENST00000622668.4; ENST00000432645.6; ENST00000441986.5; ENST00000406451.8; ENST00000456174.6; ENST00000417496.6; ENST00000471887.1; ENST00000433709.6; ENST00000413380.5; ENST00000524023.1; ENST00000428307.6; ENST00000405010.7; ENST00000413509.6; ENST00000523867.5; ENST00000461159.6
External Link	RMBase: m6A_site_749430
mod ID: M6ASITE078845		Click to Show/Hide the Full List
mod site	chr7:18509380-18509381:+		[7]
Sequence	TTTTCTCTAGCCTCAAGAAGACTGAGACCGAGCCAAACTCC
Motif Score	3.319380952
Cell/Tissue List	fibroblasts
Seq Type List	m6A-seq
Transcript ID List	ENST00000433709.6; ENST00000413509.6; ENST00000441986.5; ENST00000405010.7; ENST00000471887.1; ENST00000401921.5; ENST00000523867.5; ENST00000406072.5; ENST00000441542.6; ENST00000428307.6; ENST00000622668.4; ENST00000476135.5; ENST00000413380.5; ENST00000524023.1; ENST00000456174.6; ENST00000417496.6; ENST00000430454.5; ENST00000432645.6; ENST00000461159.6; ENST00000446646.1; ENST00000406451.8
External Link	RMBase: m6A_site_749431
mod ID: M6ASITE078846		Click to Show/Hide the Full List
mod site	chr7:18509386-18509387:+		[7]
Sequence	CTAGCCTCAAGAAGACTGAGACCGAGCCAAACTCCTGGCCA
Motif Score	2.876744048
Cell/Tissue List	fibroblasts
Seq Type List	m6A-seq
Transcript ID List	ENST00000471887.1; ENST00000456174.6; ENST00000523867.5; ENST00000430454.5; ENST00000622668.4; ENST00000441542.6; ENST00000432645.6; ENST00000524023.1; ENST00000406451.8; ENST00000413380.5; ENST00000433709.6; ENST00000413509.6; ENST00000441986.5; ENST00000405010.7; ENST00000428307.6; ENST00000406072.5; ENST00000476135.5; ENST00000401921.5; ENST00000446646.1; ENST00000417496.6; ENST00000461159.6
External Link	RMBase: m6A_site_749432
mod ID: M6ASITE078847		Click to Show/Hide the Full List
mod site	chr7:18509396-18509397:+		[7]
Sequence	GAAGACTGAGACCGAGCCAAACTCCTGGCCAACGTGCTTTG
Motif Score	2.627720238
Cell/Tissue List	fibroblasts
Seq Type List	m6A-seq
Transcript ID List	ENST00000523867.5; ENST00000428307.6; ENST00000441542.6; ENST00000401921.5; ENST00000405010.7; ENST00000432645.6; ENST00000430454.5; ENST00000406072.5; ENST00000471887.1; ENST00000456174.6; ENST00000461159.6; ENST00000476135.5; ENST00000433709.6; ENST00000406451.8; ENST00000524023.1; ENST00000413380.5; ENST00000441986.5; ENST00000413509.6; ENST00000417496.6; ENST00000622668.4; ENST00000446646.1
External Link	RMBase: m6A_site_749433
mod ID: M6ASITE078848		Click to Show/Hide the Full List
mod site	chr7:18585331-18585332:+		[8]
Sequence	GGAGCCCATCTCACCTTTAGACCTAAGGACAGACCTCAGGA
Motif Score	2.876744048
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000446646.1; ENST00000413509.6; ENST00000622668.4; ENST00000456174.6; ENST00000413380.5; ENST00000523867.5; ENST00000417496.6; ENST00000441542.6; ENST00000476135.5; ENST00000461159.6; ENST00000406451.8; ENST00000406072.5; ENST00000401921.5; ENST00000441986.5; ENST00000428307.6; ENST00000524023.1; ENST00000432645.6; ENST00000405010.7; ENST00000430454.5
External Link	RMBase: m6A_site_749434
mod ID: M6ASITE078849		Click to Show/Hide the Full List
mod site	chr7:18585339-18585340:+		[8]
Sequence	TCTCACCTTTAGACCTAAGGACAGACCTCAGGATGATGATG
Motif Score	3.643047619
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000406451.8; ENST00000428307.6; ENST00000417496.6; ENST00000441542.6; ENST00000523867.5; ENST00000413380.5; ENST00000622668.4; ENST00000441986.5; ENST00000476135.5; ENST00000406072.5; ENST00000401921.5; ENST00000413509.6; ENST00000456174.6; ENST00000405010.7; ENST00000430454.5; ENST00000461159.6; ENST00000446646.1; ENST00000524023.1; ENST00000432645.6
External Link	RMBase: m6A_site_749435
mod ID: M6ASITE078850		Click to Show/Hide the Full List
mod site	chr7:18585370-18585371:+		[8]
Sequence	GATGATGATGCCCGTGGTGGACCCTGTTGTCCGTGAGAAGC
Motif Score	3.622404762
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000432645.6; ENST00000430454.5; ENST00000476135.5; ENST00000441986.5; ENST00000428307.6; ENST00000413509.6; ENST00000413380.5; ENST00000456174.6; ENST00000441542.6; ENST00000405010.7; ENST00000406072.5; ENST00000406451.8; ENST00000417496.6; ENST00000622668.4; ENST00000524023.1; ENST00000401921.5; ENST00000446646.1; ENST00000461159.6; ENST00000523867.5
External Link	RMBase: m6A_site_749436
mod ID: M6ASITE078851		Click to Show/Hide the Full List
mod site	chr7:18585467-18585468:+		[9]
Sequence	CTGATAGCAGAGTTTCAGAAACAGCATGAGAACTTGACACG
Motif Score	2.20572619
Cell/Tissue List	NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000405010.7; ENST00000456174.6; ENST00000524023.1; ENST00000430454.5; ENST00000622668.4; ENST00000523867.5; ENST00000476135.5; ENST00000446646.1; ENST00000413380.5; ENST00000413509.6; ENST00000428307.6; ENST00000461159.6; ENST00000441542.6; ENST00000432645.6; ENST00000406072.5; ENST00000417496.6; ENST00000401921.5; ENST00000441986.5; ENST00000406451.8
External Link	RMBase: m6A_site_749437
mod ID: M6ASITE078852		Click to Show/Hide the Full List
mod site	chr7:18585478-18585479:+		[9]
Sequence	GTTTCAGAAACAGCATGAGAACTTGACACGGCAGCACCAGG
Motif Score	3.373380952
Cell/Tissue List	NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000523867.5; ENST00000405010.7; ENST00000428307.6; ENST00000406451.8; ENST00000413509.6; ENST00000441986.5; ENST00000446646.1; ENST00000417496.6; ENST00000461159.6; ENST00000524023.1; ENST00000456174.6; ENST00000476135.5; ENST00000406072.5; ENST00000430454.5; ENST00000432645.6; ENST00000622668.4; ENST00000401921.5; ENST00000413380.5; ENST00000441542.6
External Link	RMBase: m6A_site_749438
mod ID: M6ASITE078853		Click to Show/Hide the Full List
mod site	chr7:18590373-18590374:+		[10]
Sequence	GCCATAAAACAGCAACAAGAACTCCTAGAAAAGGAGCAGAA
Motif Score	3.373380952
Cell/Tissue List	Huh7; endometrial; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000461159.6; ENST00000406072.5; ENST00000417496.6; ENST00000406451.8; ENST00000523867.5; ENST00000430454.5; ENST00000446646.1; ENST00000405010.7; ENST00000456174.6; ENST00000524023.1; ENST00000432645.6; ENST00000441986.5; ENST00000622668.4; ENST00000401921.5; ENST00000441542.6; ENST00000413509.6; ENST00000413380.5; ENST00000428307.6
External Link	RMBase: m6A_site_749439
mod ID: M6ASITE078854		Click to Show/Hide the Full List
mod site	chr7:18590394-18590395:+		[10]
Sequence	CTCCTAGAAAAGGAGCAGAAACTGGAGCAGCAGAGGCAAGA
Motif Score	2.627720238
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000417496.6; ENST00000428307.6; ENST00000432645.6; ENST00000413380.5; ENST00000401921.5; ENST00000406451.8; ENST00000441986.5; ENST00000405010.7; ENST00000441542.6; ENST00000523867.5; ENST00000622668.4; ENST00000461159.6; ENST00000456174.6; ENST00000413509.6; ENST00000524023.1; ENST00000406072.5; ENST00000446646.1
External Link	RMBase: m6A_site_749440
mod ID: M6ASITE078855		Click to Show/Hide the Full List
mod site	chr7:18590415-18590416:+		[10]
Sequence	CTGGAGCAGCAGAGGCAAGAACAGGAAGTAGAGAGGCATCG
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000432645.6; ENST00000456174.6; ENST00000441986.5; ENST00000461159.6; ENST00000441542.6; ENST00000622668.4; ENST00000446646.1; ENST00000428307.6; ENST00000413509.6; ENST00000401921.5; ENST00000406072.5; ENST00000405010.7; ENST00000524023.1; ENST00000413380.5; ENST00000523867.5; ENST00000406451.8; ENST00000417496.6
External Link	RMBase: m6A_site_749441
mod ID: M6ASITE078856		Click to Show/Hide the Full List
mod site	chr7:18590442-18590443:+		[10]
Sequence	GTAGAGAGGCATCGCAGAGAACAGCAGCTTCCTCCTCTCAG
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000428307.6; ENST00000406072.5; ENST00000524023.1; ENST00000405010.7; ENST00000413509.6; ENST00000461159.6; ENST00000523867.5; ENST00000622668.4; ENST00000417496.6; ENST00000441542.6; ENST00000432645.6; ENST00000441986.5; ENST00000406451.8; ENST00000401921.5; ENST00000446646.1; ENST00000456174.6; ENST00000413380.5
External Link	RMBase: m6A_site_749442
mod ID: M6ASITE078857		Click to Show/Hide the Full List
mod site	chr7:18648678-18648679:+		[11]
Sequence	CCAGCAGCAGATCCACATGAACAAAGTAAGCCTCCAAGCCA
Motif Score	2.951386905
Cell/Tissue List	endometrial; HEC-1-A; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000456174.6; ENST00000523867.5; ENST00000432645.6; ENST00000622668.4; ENST00000417496.6; ENST00000401921.5; ENST00000406451.8; ENST00000441542.6; ENST00000428307.6; ENST00000461159.6; ENST00000405010.7; ENST00000406072.5; ENST00000524023.1
External Link	RMBase: m6A_site_749443
mod ID: M6ASITE078858		Click to Show/Hide the Full List
mod site	chr7:18666232-18666233:+		[8]
Sequence	CTGCTTTCGAAATCTATTGAACAACTGAAGCAACCAGGCAG
Motif Score	2.951386905
Cell/Tissue List	peripheral-blood; endometrial; HEC-1-A; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000417496.6; ENST00000461159.6; ENST00000432645.6; ENST00000401921.5; ENST00000622668.4; ENST00000441542.6; ENST00000524023.1; ENST00000523867.5; ENST00000405010.7; ENST00000406451.8; ENST00000428307.6; ENST00000406072.5; ENST00000456174.6
External Link	RMBase: m6A_site_749444
mod ID: M6ASITE078859		Click to Show/Hide the Full List
mod site	chr7:18666288-18666289:+		[12]
Sequence	AGAGGAAGAGCTTCAGGGGGACCAGGCGATGCAGGAAGACA
Motif Score	3.622404762
Cell/Tissue List	U2OS; fibroblasts; Jurkat; peripheral-blood; GSC-11; iSLK; endometrial; HEC-1-A; MM6
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000406451.8; ENST00000417496.6; ENST00000405010.7; ENST00000406072.5; ENST00000524023.1; ENST00000432645.6; ENST00000401921.5; ENST00000456174.6; ENST00000523867.5; ENST00000428307.6; ENST00000441542.6; ENST00000622668.4; ENST00000461159.6
External Link	RMBase: m6A_site_749445
mod ID: M6ASITE078860		Click to Show/Hide the Full List
mod site	chr7:18666306-18666307:+		[12]
Sequence	GGACCAGGCGATGCAGGAAGACAGAGCGCCCTCTAGTGGCA
Motif Score	2.897386905
Cell/Tissue List	U2OS; H1A; H1B; fibroblasts; LCLs; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; TREX; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000622668.4; ENST00000406072.5; ENST00000417496.6; ENST00000456174.6; ENST00000432645.6; ENST00000405010.7; ENST00000441542.6; ENST00000524023.1; ENST00000406451.8; ENST00000461159.6; ENST00000428307.6; ENST00000523867.5; ENST00000401921.5
External Link	RMBase: m6A_site_749446
mod ID: M6ASITE078861		Click to Show/Hide the Full List
mod site	chr7:18666373-18666374:+		[13]
Sequence	TGTGTGGATGACACACTGGGACAAGTTGGGGCTGTGAAGGT
Motif Score	3.643047619
Cell/Tissue List	A549; U2OS; H1A; H1B; hESCs; fibroblasts; LCLs; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000461159.6; ENST00000622668.4; ENST00000524023.1; ENST00000401921.5; ENST00000405010.7; ENST00000523867.5; ENST00000432645.6; ENST00000441542.6; ENST00000428307.6; ENST00000417496.6; ENST00000406072.5; ENST00000406451.8; ENST00000456174.6
External Link	RMBase: m6A_site_749447
mod ID: M6ASITE078862		Click to Show/Hide the Full List
mod site	chr7:18666403-18666404:+		[13]
Sequence	GCTGTGAAGGTCAAGGAGGAACCAGTGGACAGTGATGAAGA
Motif Score	2.930744048
Cell/Tissue List	A549; U2OS; H1B; H1A; hESCs; fibroblasts; LCLs; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000524023.1; ENST00000428307.6; ENST00000456174.6; ENST00000406451.8; ENST00000441542.6; ENST00000401921.5; ENST00000432645.6; ENST00000622668.4; ENST00000461159.6; ENST00000405010.7; ENST00000417496.6; ENST00000523867.5; ENST00000406072.5
External Link	RMBase: m6A_site_749448
mod ID: M6ASITE078863		Click to Show/Hide the Full List
mod site	chr7:18666411-18666412:+		[13]
Sequence	GGTCAAGGAGGAACCAGTGGACAGTGATGAAGATGCTCAGA
Motif Score	3.643047619
Cell/Tissue List	A549; U2OS; H1B; H1A; hESCs; fibroblasts; LCLs; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000428307.6; ENST00000456174.6; ENST00000622668.4; ENST00000461159.6; ENST00000441542.6; ENST00000432645.6; ENST00000523867.5; ENST00000406072.5; ENST00000401921.5; ENST00000405010.7; ENST00000417496.6; ENST00000524023.1; ENST00000406451.8
External Link	RMBase: m6A_site_749449
mod ID: M6ASITE078864		Click to Show/Hide the Full List
mod site	chr7:18666527-18666528:+		[12]
Sequence	TAATTAAAGTCATTATCTGAACATGAAATGCATTGCAGGTT
Motif Score	2.951386905
Cell/Tissue List	U2OS; fibroblasts; LCLs; H1299; Huh7; MSC; TREX; iSLK; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000523867.5; ENST00000401921.5; ENST00000406451.8; ENST00000622668.4; ENST00000417496.6; ENST00000441542.6; ENST00000406072.5; ENST00000461159.6; ENST00000456174.6; ENST00000524023.1; ENST00000428307.6; ENST00000432645.6; ENST00000405010.7
External Link	RMBase: m6A_site_749450
mod ID: M6ASITE078865		Click to Show/Hide the Full List
mod site	chr7:18996133-18996134:+		[6]
Sequence	CCCCACCCCAGTACCCTCAGACATGTCTTGTCTGCTGCCTG
Motif Score	2.897386905
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000496026.1; ENST00000401921.5; ENST00000406451.8; ENST00000490851.5
External Link	RMBase: m6A_site_749451
mod ID: M6ASITE078866		Click to Show/Hide the Full List
mod site	chr7:18996174-18996175:+		[6]
Sequence	GGTGGCACAGATTCAATGGAACATAAACACTGGGCACAAAA
Motif Score	2.951386905
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000490851.5; ENST00000496026.1; ENST00000406451.8; ENST00000401921.5
External Link	RMBase: m6A_site_749452
mod ID: M6ASITE078867		Click to Show/Hide the Full List
mod site	chr7:18996180-18996181:+		[7]
Sequence	ACAGATTCAATGGAACATAAACACTGGGCACAAAATTCTGA
Motif Score	2.20572619
Cell/Tissue List	fibroblasts; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000406451.8; ENST00000490851.5; ENST00000496026.1; ENST00000401921.5
External Link	RMBase: m6A_site_749453
mod ID: M6ASITE078868		Click to Show/Hide the Full List
mod site	chr7:18996201-18996202:+		[7]
Sequence	CACTGGGCACAAAATTCTGAACAGCAGCTTCACTTGTTCTT
Motif Score	2.951386905
Cell/Tissue List	fibroblasts; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000490851.5; ENST00000406451.8; ENST00000496026.1
External Link	RMBase: m6A_site_749454
mod ID: M6ASITE078869		Click to Show/Hide the Full List
mod site	chr7:18996229-18996230:+		[7]
Sequence	TTCACTTGTTCTTTGGATGGACTTGAAAGGGCATTAAAGAT
Motif Score	4.065041667
Cell/Tissue List	fibroblasts; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000406451.8; ENST00000496026.1; ENST00000490851.5
External Link	RMBase: m6A_site_749455
mod ID: M6ASITE078870		Click to Show/Hide the Full List
mod site	chr7:18996289-18996290:+		[7]
Sequence	TGATTCTAGAGTTACAGTAAACCACGATTGGAAGAAACTGC
Motif Score	2.185083333
Cell/Tissue List	fibroblasts; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000490851.5; ENST00000406451.8; ENST00000496026.1
External Link	RMBase: m6A_site_749456
mod ID: M6ASITE078871		Click to Show/Hide the Full List
mod site	chr7:18996305-18996306:+		[6]
Sequence	GTAAACCACGATTGGAAGAAACTGCTTCCAGCATGCTTTTA
Motif Score	2.627720238
Cell/Tissue List	iSLK; TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000496026.1; ENST00000490851.5; ENST00000406451.8
External Link	RMBase: m6A_site_749457
mod ID: M6ASITE078872		Click to Show/Hide the Full List
mod site	chr7:18996350-18996351:+		[6]
Sequence	GCTGGGTGACCCACTCCTAGACACCAAGTTTGAACTAGAAA
Motif Score	2.897386905
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000406451.8; ENST00000490851.5
External Link	RMBase: m6A_site_749458

Ref 1	Clinical pipeline report, company report or official report of Neuronova.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Systematic identification of abundant A-to-I editing sites in the human transcriptome. Nat Biotechnol. 2004 Aug;22(8):1001-5. doi: 10.1038/nbt996. Epub 2004 Jul 18.
Ref 4	High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq. Nucleic Acids Res. 2017 Mar 17;45(5):2341-2353. doi: 10.1093/nar/gkw1321.
Ref 5	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Elife. 2016 Jul 2;5:e15528. doi: 10.7554/eLife.15528.
Ref 6	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 7	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 8	R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
Ref 9	METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification. Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 10.1016/j.stem.2017.11.016. Epub 2017 Dec 28.
Ref 10	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 11	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 12	RNA-methylation-dependent RNA processing controls the speed of the circadian clock. Cell. 2013 Nov 7;155(4):793-806. doi: 10.1016/j.cell.2013.10.026.
Ref 13	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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