m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01229)

Target Name	Alpha-(1,3)-fucosyltransferase 4 (FUT4)
Synonyms	1,3; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; EC 2.4.1.152; ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase Click to Show/Hide
Gene Name	FUT4
Chromosomal Location	11q21
Family	Glycosyltransferase 10 family
Function	Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins (PubMed:29593094, PubMed:1702034, PubMed:1716630). Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins (PubMed:29593094, PubMed:1716630). Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis (By similarity). In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (PubMed:1716630, PubMed:11278338). Click to Show/Hide
Gene ID	2526
Uniprot ID	FUT4_HUMAN
HGNC ID	HGNC:4015
KEGG ID	hsa:2526

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: ELAV-like protein 1 (ELAVL1)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05888		Crosstalk Info
Epigenetic Regulator	HOXB cluster antisense RNA 1 (HOXB-AS1)
Regulated Target	ELAV-like protein 1 (HuR/ELAVL1)
Crosstalk relationship	ncRNA → m6A
Disease	Multiple myeloma	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01229)

Alpha-(1,3)-fucosyltransferase 4 (FUT4)

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE005324		Click to Show/Hide the Full List
mod site	chr11:94545750-94545751:+
Sequence	GCGCTCCCCTGGAAGCGACCCAGGGGAGGCCAAGTTGTCAG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3; ENST00000446230.6
External Link	RMBase: m5C_site_8861

N6-methyladenosine (m6A)

In total 40 m6A sequence/site(s) in this target gene
mod ID: M6ASITE008089		Click to Show/Hide the Full List
mod site	chr11:94544021-94544022:+		[2]
Sequence	CTGTACCTTCCCAGGGATGAACCGGGCCTTCCCTCTGGAAG
Motif Score	2.930744048
Cell/Tissue List	CD34; MM6; peripheral-blood; HEK293T; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3
External Link	RMBase: m6A_site_159704
mod ID: M6ASITE008090		Click to Show/Hide the Full List
mod site	chr11:94544099-94544100:+		[2]
Sequence	GTGGGCGCGCGCAGAGGGAAACCGGATCAGTTGAGAGAGAA
Motif Score	2.185083333
Cell/Tissue List	CD34; MM6; peripheral-blood; HEK293T; iSLK; MSC; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3
External Link	RMBase: m6A_site_159705
mod ID: M6ASITE008091		Click to Show/Hide the Full List
mod site	chr11:94544373-94544374:+		[3]
Sequence	CGCGGCCTTTGCATTCTGGGACCGCCCCCTTCCATTCCCGG
Motif Score	3.622404762
Cell/Tissue List	HEK293T; MSC; iSLK; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159706
mod ID: M6ASITE008092		Click to Show/Hide the Full List
mod site	chr11:94544586-94544587:+		[4]
Sequence	GAGGCCGGGGGCTGCCATGGACCGTCTGTGTGCTGGCGGCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; MM6; HEK293T; HEK293A-TOA; iSLK; MSC; TIME; NB4; AML
Seq Type List	MeRIP-seq; m6A-seq; miCLIP
Transcript ID List	ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159707
mod ID: M6ASITE008093		Click to Show/Hide the Full List
mod site	chr11:94544938-94544939:+		[5]
Sequence	GGTGGATCTGCGCGTGTTGGACTACGAGGAGGCAGCGGCGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; H1B; hESCs; MM6; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159708
mod ID: M6ASITE008094		Click to Show/Hide the Full List
mod site	chr11:94545019-94545020:+		[5]
Sequence	CCAGCGCTGGGTTTGGATGAACTTCGAGTCGCCCTCGCACT
Motif Score	3.373380952
Cell/Tissue List	HeLa; CD34; HEK293T; A549; U2OS; H1A; H1B; hESCs; GM12878; MM6; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159709
mod ID: M6ASITE008095		Click to Show/Hide the Full List
mod site	chr11:94545100-94545101:+		[5]
Sequence	GACGCTCTCCTACCGGGCGGACTCGGACGTCTTTGTGCCTT
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HEK293T; A549; U2OS; H1A; H1B; hESCs; GM12878; H1299; MM6; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000543336.5; ENST00000358752.3
External Link	RMBase: m6A_site_159710
mod ID: M6ASITE008096		Click to Show/Hide the Full List
mod site	chr11:94545191-94545192:+		[5]
Sequence	GCCCCGCCACTGTCCAGGAAACAGGGGCTGGTGGCATGGGT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; GM12878; H1299; MM6; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159711
mod ID: M6ASITE008097		Click to Show/Hide the Full List
mod site	chr11:94545376-94545377:+		[5]
Sequence	GTTCTACCTGGCTTTCGAGAACTCGCAGCACCTGGATTATA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; H1A; H1B; GM12878; MM6; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159713
mod ID: M6ASITE008098		Click to Show/Hide the Full List
mod site	chr11:94545460-94545461:+		[5]
Sequence	GCCGGTGGTGCTGGGCCCAGACCGTGCCAACTACGAGCGCT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; A549; GM12878; MM6; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159714
mod ID: M6ASITE008099		Click to Show/Hide the Full List
mod site	chr11:94545544-94545545:+		[6]
Sequence	TGCCTCCTCCCTGGCCTCGTACCTGCTTTTCCTCGACCGCA
Motif Score	2.8355
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159715
mod ID: M6ASITE008100		Click to Show/Hide the Full List
mod site	chr11:94545679-94545680:+		[5]
Sequence	GGCTGTACAGAGGGCTGGGGACCGGCCCAAGAGCATACGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; H1A; H1B; hESCs; GM12878; MM6; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159718
mod ID: M6ASITE008101		Click to Show/Hide the Full List
mod site	chr11:94545700-94545701:+		[5]
Sequence	CCGGCCCAAGAGCATACGGAACTTGGCCAGCTGGTTCGAGC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; H1A; H1B; hESCs; GM12878; MM6; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159719
mod ID: M6ASITE008102		Click to Show/Hide the Full List
mod site	chr11:94545831-94545832:+		[5]
Sequence	CATGGGAGTAAGTTCTTCAAACACCCATTTTTGCTCTATGG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; A549; H1B; GM12878; MM6; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159722
mod ID: M6ASITE008103		Click to Show/Hide the Full List
mod site	chr11:94545859-94545860:+		[7]
Sequence	TTTTGCTCTATGGGAAAAAAACGATTTACCAATTAATATTA
Motif Score	2.179660714
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159723
mod ID: M6ASITE008104		Click to Show/Hide the Full List
mod site	chr11:94546143-94546144:+		[5]
Sequence	CCCGATTCACGTTTTTCTGGACCAAGGTGAAGCAAATTTGT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543336.5; ENST00000446230.6; ENST00000358752.3
External Link	RMBase: m6A_site_159724
mod ID: M6ASITE008105		Click to Show/Hide the Full List
mod site	chr11:94546201-94546202:+		[5]
Sequence	TGTTGGTGGAGAGTGGAAGGACTGTGGCTGCAGGTGGGACT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159725
mod ID: M6ASITE008106		Click to Show/Hide the Full List
mod site	chr11:94546219-94546220:+		[5]
Sequence	GGACTGTGGCTGCAGGTGGGACTTTGTTGTTTGGATTCCTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000446230.6; ENST00000543336.5; ENST00000358752.3
External Link	RMBase: m6A_site_159726
mod ID: M6ASITE008107		Click to Show/Hide the Full List
mod site	chr11:94546292-94546293:+		[8]
Sequence	CAGTCCAAGAGGGGCCGCTGACTTCTTTCACAAGTACTATC
Motif Score	3.28175
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000543336.5; ENST00000446230.6; ENST00000358752.3
External Link	RMBase: m6A_site_159729
mod ID: M6ASITE008108		Click to Show/Hide the Full List
mod site	chr11:94546365-94546366:+		[5]
Sequence	CTGGATTGTCCTTGGAGGAAACTTAAGATGAATACATGCGT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; H1A; H1B; hESCs; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159731
mod ID: M6ASITE008109		Click to Show/Hide the Full List
mod site	chr11:94546480-94546481:+		[4]
Sequence	GGAGTTCAGTATTTAATGAAACCCTATGGAGAATTTATCCC
Motif Score	2.185083333
Cell/Tissue List	HEK293T; HeLa; A549; GM12878; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000446230.6; ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159732
mod ID: M6ASITE008110		Click to Show/Hide the Full List
mod site	chr11:94546504-94546505:+		[9]
Sequence	TATGGAGAATTTATCCCTTTACAATGTGAATAGTCATCTCC
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159733
mod ID: M6ASITE008111		Click to Show/Hide the Full List
mod site	chr11:94546637-94546638:+
Sequence	TTTTTCCCTCTTCCCAGAAAACCAGTCTGTGTTTACAGACA
Motif Score	2.185083333
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3; ENST00000446230.6
External Link	RMBase: m6A_site_159734
mod ID: M6ASITE008112		Click to Show/Hide the Full List
mod site	chr11:94546655-94546656:+
Sequence	AAACCAGTCTGTGTTTACAGACAGAAGAGAAGGAAGCCATA
Motif Score	2.897386905
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000446230.6; ENST00000543336.5; ENST00000358752.3
External Link	RMBase: m6A_site_159735
mod ID: M6ASITE008113		Click to Show/Hide the Full List
mod site	chr11:94546717-94546718:+		[10]
Sequence	TTATTTCATGTCTTTACTGGACCTGAAATTTAAACTGCAAT
Motif Score	3.622404762
Cell/Tissue List	HEK293T; iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159736
mod ID: M6ASITE008114		Click to Show/Hide the Full List
mod site	chr11:94546730-94546731:+		[10]
Sequence	TTACTGGACCTGAAATTTAAACTGCAATGCCAGTCCTGCAG
Motif Score	2.627720238
Cell/Tissue List	HEK293T; iSLK; AML
Seq Type List	MeRIP-seq; miCLIP
Transcript ID List	ENST00000543336.5; ENST00000358752.3; ENST00000446230.6
External Link	RMBase: m6A_site_159737
mod ID: M6ASITE008115		Click to Show/Hide the Full List
mod site	chr11:94546776-94546777:+		[10]
Sequence	CTGGCATTACCCTCTGCAGAACAGTGAAAGGTATTGCACTA
Motif Score	2.951386905
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159738
mod ID: M6ASITE008116		Click to Show/Hide the Full List
mod site	chr11:94547015-94547016:+		[9]
Sequence	CAGTGGTATAGCATATCCTCACATTTCTAGTGCCCTTGAGA
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3; ENST00000446230.6
External Link	RMBase: m6A_site_159739
mod ID: M6ASITE008117		Click to Show/Hide the Full List
mod site	chr11:94547059-94547060:+		[9]
Sequence	TGCTATGGAACCAATCTTGAACATACATGCATTGACTTGAC
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543336.5; ENST00000446230.6; ENST00000358752.3
External Link	RMBase: m6A_site_159740
mod ID: M6ASITE008118		Click to Show/Hide the Full List
mod site	chr11:94549241-94549242:+		[11]
Sequence	GTGTTGAGAGGATAGATTAGACACTTGAAGTACTCAGGATA
Motif Score	2.897386905
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000358752.3; ENST00000543336.5; rmsk_3628605; ENST00000446230.6
External Link	RMBase: m6A_site_159741
mod ID: M6ASITE008119		Click to Show/Hide the Full List
mod site	chr11:94549358-94549359:+		[5]
Sequence	AGGTCCAGGCCCACTGAAGGACTTGCATAACATTACAATAG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; MM6; HEK293A-TOA; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543336.5; ENST00000446230.6; ENST00000358752.3
External Link	RMBase: m6A_site_159742
mod ID: M6ASITE008120		Click to Show/Hide the Full List
mod site	chr11:94549389-94549390:+		[5]
Sequence	ATTACAATAGCAGTGGCAGAACCAGCCATGCTTCTGCAAAT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; A549; GM12878; MM6; HEK293A-TOA; iSLK; MSC; TIME; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000446230.6; rmsk_3628607; ENST00000543336.5; ENST00000358752.3
External Link	RMBase: m6A_site_159743
mod ID: M6ASITE008121		Click to Show/Hide the Full List
mod site	chr11:94549439-94549440:+		[5]
Sequence	TTTGAGCCTCTGTCACCTGAACTGCAAAATGAGTGGGTTAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; GM12878; MM6; HEK293A-TOA; iSLK; MSC; TIME; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	rmsk_3628607; ENST00000358752.3; ENST00000446230.6; ENST00000543336.5
External Link	RMBase: m6A_site_159744
mod ID: M6ASITE008122		Click to Show/Hide the Full List
mod site	chr11:94549460-94549461:+		[5]
Sequence	CTGCAAAATGAGTGGGTTAGACAAAATCATCTGTTGGGACC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; A549; GM12878; MM6; HEK293A-TOA; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3; rmsk_3628607; ENST00000446230.6
External Link	RMBase: m6A_site_159745
mod ID: M6ASITE008123		Click to Show/Hide the Full List
mod site	chr11:94549478-94549479:+		[5]
Sequence	AGACAAAATCATCTGTTGGGACCTCCTAGTTCCACGTGCTA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; A549; GM12878; MM6; HEK293A-TOA; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3628607; ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159746
mod ID: M6ASITE008124		Click to Show/Hide the Full List
mod site	chr11:94549510-94549511:+		[8]
Sequence	CACGTGCTATCATTCTACTAACTGGCACCCTAAGGTTGAAA
Motif Score	2.590089286
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000358752.3; ENST00000543336.5; ENST00000446230.6
External Link	RMBase: m6A_site_159747
mod ID: M6ASITE008125		Click to Show/Hide the Full List
mod site	chr11:94549572-94549573:+		[5]
Sequence	TGGCTTCCTTACAGTCTGGAACTGACAATATGCAGGAGCAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; MM6; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000446230.6; ENST00000358752.3; ENST00000543336.5
External Link	RMBase: m6A_site_159748
mod ID: M6ASITE008126		Click to Show/Hide the Full List
mod site	chr11:94549576-94549577:+		[9]
Sequence	TTCCTTACAGTCTGGAACTGACAATATGCAGGAGCAGTAAA
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T; AML
Seq Type List	MAZTER-seq; miCLIP
Transcript ID List	ENST00000543336.5; ENST00000358752.3; ENST00000446230.6
External Link	RMBase: m6A_site_159749
mod ID: M6ASITE008127		Click to Show/Hide the Full List
mod site	chr11:94549596-94549597:+		[10]
Sequence	ACAATATGCAGGAGCAGTAAACTGGCAGAAAACCAGGAATC
Motif Score	2.627720238
Cell/Tissue List	HEK293T; MM6; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000543336.5; ENST00000446230.6; ENST00000358752.3
External Link	RMBase: m6A_site_159750
mod ID: M6ASITE008128		Click to Show/Hide the Full List
mod site	chr11:94549607-94549608:+		[10]
Sequence	GAGCAGTAAACTGGCAGAAAACCAGGAATCAGAGAAAGAAA
Motif Score	2.185083333
Cell/Tissue List	HEK293T; MM6; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000543336.5; ENST00000358752.3; ENST00000446230.6
External Link	RMBase: m6A_site_159751

2'-O-Methylation (2'-O-Me)

In total 1 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000022		Click to Show/Hide the Full List
mod site	chr11:94548856-94548857:+		[12]
Sequence	TAACAGAAGACGGTCTGACTTGCTTTCAGTATTCACAAGTT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000543336.5; ENST00000446230.6; ENST00000358752.3
External Link	RMBase: Nm_site_1120

Ref 1	Prediction of Transporter-Mediated Drug-Drug Interactions for Baricitinib. Clin Transl Sci. 2017 Nov;10(6):509-519. doi: 10.1111/cts.12486. Epub 2017 Jul 27.
Ref 2	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 3	Dynamics of Human and Viral RNA Methylation during Zika Virus Infection. Cell Host Microbe. 2016 Nov 9;20(5):666-673. doi: 10.1016/j.chom.2016.10.002. Epub 2016 Oct 20.
Ref 4	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 7	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 8	The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.
Ref 9	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 10	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 11	The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003.
Ref 12	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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