m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00888)

Target Name	Cysteine protease ATG4B (ATG4B)
Synonyms	EC 3.4.22.-; AUT-like 1 cysteine endopeptidase; Autophagy-related cysteine endopeptidase 1; Autophagin-1; Autophagy-related protein 4 homolog B; HsAPG4B; hAPG4B Click to Show/Hide
Gene Name	ATG4B
Chromosomal Location	2q37.3
Family	Peptidase C54 family
Function	Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins (PubMed:15169837, PubMed:15187094, PubMed:17347651, PubMed:19322194, PubMed:21177865, PubMed:26378241, PubMed:29232556, PubMed:28821708, PubMed:30443548, PubMed:30661429, PubMed:22302004, PubMed:27527864, PubMed:28633005, PubMed:30076329). Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy (PubMed:33773106, PubMed:33909989). The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine (PubMed:15169837, PubMed:15187094, PubMed:17347651, PubMed:20818167, PubMed:19322194, PubMed:21177865, PubMed:22302004, PubMed:27527864, PubMed:28633005, PubMed:29458288, PubMed:30661429, PubMed:28287329). Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (PubMed:15169837, PubMed:15187094, PubMed:17347651, PubMed:19322194, PubMed:21177865, PubMed:22302004). Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3 (PubMed:31315929, PubMed:33773106). In addition to the protease activity, also mediates delipidation of ATG8 family proteins (PubMed:15187094, PubMed:28633005, PubMed:29458288, PubMed:32686895, PubMed:33909989, PubMed:19322194). Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy (PubMed:15187094, PubMed:29458288, PubMed:32686895, PubMed:33909989, PubMed:19322194). Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, by catalyzing delipidation of ATG8 proteins conjugated to phosphatidylserine (PS) (PubMed:33909989). Compared to other members of the family (ATG4A, ATG4C or ATG4C), constitutes the major protein for proteolytic activation of ATG8 proteins, while it displays weaker delipidation activity than other ATG4 paralogs (PubMed:29458288, PubMed:30661429). Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy (PubMed:33773106). Click to Show/Hide
Gene ID	23192
Uniprot ID	ATG4B_HUMAN
HGNC ID	HGNC:20790
KEGG ID	hsa:23192

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05147		Crosstalk Info
Epigenetic Regulator	Prostate cancer associated transcript 6 (PCAT6)
Regulated Target	Heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1)
Crosstalk relationship	ncRNA → m6A
Disease	Breast cancer	Disease Info
Drug	Olaparib	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00888)

Cysteine protease ATG4B (ATG4B)

N4-acetylcytidine (ac4C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000040		Click to Show/Hide the Full List
mod site	chr2:241637706-241637707:+		[2]
Sequence	CGGGTCAGTCGGCGGCCGGACTGGGAAGATGGACGCAGGTG
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000419606.5; ENST00000475195.5; ENST00000479554.5; ENST00000425239.5; ENST00000400772.6; ENST00000405546.7; ENST00000404914.8; ENST00000493618.5; ENST00000465399.5; ENST00000468018.5; ENST00000483778.5; ENST00000482507.5; ENST00000494465.5; ENST00000402096.5; ENST00000625810.2; ENST00000491867.5
External Link	RMBase: ac4C_site_1176

Adenosine-to-Inosine editing (A-to-I)

In total 3 m6A sequence/site(s) in this target gene
mod ID: A2ISITE010321		Click to Show/Hide the Full List
mod site	chr2:241648022-241648023:+		[3]
Sequence	ACTCGGGAGGATGAGGCAGGAGAATTTCTTGAACCCGGAAG
Transcript ID List	ENST00000468018.5; ENST00000475195.5; ENST00000482507.5; ENST00000415107.5; ENST00000479554.5; ENST00000491867.5; ENST00000402096.5; ENST00000405546.7; ENST00000425239.5; ENST00000400772.6; ENST00000625810.2; ENST00000419606.5; ENST00000494465.5; ENST00000483778.5; ENST00000465399.5; ENST00000430617.6; rmsk_863882; ENST00000493618.5; ENST00000404914.8; ENST00000400771.7
External Link	RMBase: RNA-editing_site_84822
mod ID: A2ISITE010322		Click to Show/Hide the Full List
mod site	chr2:241652312-241652313:+		[4]
Sequence	CTCTTGGCCGCCTTGGATGCAGGTTTGTCCCCAGCCTCCAT
Transcript ID List	ENST00000483778.5; ENST00000402096.5; ENST00000465399.5; ENST00000405546.7; ENST00000344376.9; ENST00000468018.5; ENST00000475195.5; ENST00000400771.7; ENST00000430617.6; ENST00000482507.5; ENST00000419606.5; ENST00000479554.5; ENST00000404914.8; ENST00000493618.5; ENST00000425239.5; ENST00000415107.5; ENST00000400772.6; ENST00000494465.5; ENST00000491867.5
External Link	RMBase: RNA-editing_site_84823
mod ID: A2ISITE010323		Click to Show/Hide the Full List
mod site	chr2:241663889-241663890:+		[3]
Sequence	CACGATCTTGGCTCACTGCAATTTCCGCTGCCCAGGTTCAA
Transcript ID List	ENST00000482507.5; ENST00000494465.5; ENST00000429899.1; ENST00000402096.5; ENST00000404914.8; ENST00000400771.7; ENST00000344376.9; ENST00000405546.7
External Link	RMBase: RNA-editing_site_84824

N1-methyladenosine (m1A)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M1ASITE000075		Click to Show/Hide the Full List
mod site	chr2:241637692-241637693:+		[5]
Sequence	GGAGCGACGCCGCTCGGGTCAGTCGGCGGCCGGACTGGGAA
Cell/Tissue List	HEK293T
Seq Type List	m1A-MAP-seq
Transcript ID List	ENST00000483778.5; ENST00000465399.5; ENST00000419606.5; ENST00000625810.2; ENST00000475195.5; ENST00000494465.5; ENST00000404914.8; ENST00000491867.5; ENST00000402096.5; ENST00000400772.6; ENST00000479554.5; ENST00000405546.7
External Link	RMBase: m1A_site_611

5-methylcytidine (m5C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002552		Click to Show/Hide the Full List
mod site	chr2:241666640-241666641:+		[6]
Sequence	GTGAAAGCATGTCTCCCTTTCTAGGAAGGTTGTGCAGGACC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000494465.5; ENST00000400771.7; ENST00000405546.7; ENST00000429899.1; ENST00000344376.9; ENST00000428861.1; ENST00000402096.5; ENST00000482507.5; ENST00000404914.8
External Link	RMBase: m5C_site_28212
mod ID: M5CSITE002553		Click to Show/Hide the Full List
mod site	chr2:241673321-241673322:+
Sequence	TAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCT
Cell/Tissue List	lung
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000404914.8; ENST00000475693.1; ENST00000405546.7
External Link	RMBase: m5C_site_28213

N6-methyladenosine (m6A)

In total 70 m6A sequence/site(s) in this target gene
mod ID: M6ASITE050838		Click to Show/Hide the Full List
mod site	chr2:241637385-241637386:+		[7]
Sequence	AGATGGCTGCTCGGACGGGGACAGAGCTCGCCTCTGCCGCC
Motif Score	3.643047619
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000405546.7
External Link	RMBase: m6A_site_519039
mod ID: M6ASITE050840		Click to Show/Hide the Full List
mod site	chr2:241637472-241637473:+		[7]
Sequence	GGCACACAGTGTCCCGTCGGACAGCAGAACCAGCCGTCGTC
Motif Score	3.643047619
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000405546.7
External Link	RMBase: m6A_site_519040
mod ID: M6ASITE050841		Click to Show/Hide the Full List
mod site	chr2:241637480-241637481:+		[7]
Sequence	GTGTCCCGTCGGACAGCAGAACCAGCCGTCGTCCCACGACA
Motif Score	2.930744048
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000405546.7
External Link	RMBase: m6A_site_519041
mod ID: M6ASITE050842		Click to Show/Hide the Full List
mod site	chr2:241637705-241637706:+		[8]
Sequence	TCGGGTCAGTCGGCGGCCGGACTGGGAAGATGGACGCAGGT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000479554.5; ENST00000404914.8; ENST00000494465.5; ENST00000419606.5; ENST00000493618.5; ENST00000483778.5; ENST00000625810.2; ENST00000405546.7; ENST00000491867.5; ENST00000465399.5; ENST00000482507.5; ENST00000402096.5; ENST00000475195.5; ENST00000468018.5; ENST00000400772.6
External Link	RMBase: m6A_site_519042
mod ID: M6ASITE050843		Click to Show/Hide the Full List
mod site	chr2:241638306-241638307:+		[8]
Sequence	TTCCGTGACGAGAAAGAGAAACAGTGAATTTGTATCATCGG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000425239.5; ENST00000400771.7; ENST00000493618.5; ENST00000405546.7; ENST00000400772.6; ENST00000415107.5; ENST00000402096.5; ENST00000482507.5; ENST00000475195.5; ENST00000468018.5; ENST00000465399.5; ENST00000479554.5; ENST00000494465.5; ENST00000419606.5; ENST00000430617.6; ENST00000625810.2; ENST00000404914.8; ENST00000491867.5; ENST00000483778.5
External Link	RMBase: m6A_site_519043
mod ID: M6ASITE050844		Click to Show/Hide the Full List
mod site	chr2:241651024-241651025:+		[9]
Sequence	AACAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGT
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000494465.5; ENST00000483778.5; ENST00000400772.6; ENST00000415107.5; ENST00000479554.5; ENST00000482507.5; ENST00000425239.5; ENST00000491867.5; ENST00000468018.5; ENST00000402096.5; ENST00000625810.2; ENST00000344376.9; ENST00000405546.7; ENST00000493618.5; ENST00000404914.8; ENST00000430617.6; ENST00000419606.5; ENST00000465399.5; ENST00000400771.7; ENST00000475195.5
External Link	RMBase: m6A_site_519044
mod ID: M6ASITE050845		Click to Show/Hide the Full List
mod site	chr2:241651062-241651063:+		[8]
Sequence	AGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGTTTGGATA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; MM6; CD4T; peripheral-blood; HEK293T; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000491867.5; ENST00000494465.5; ENST00000425239.5; ENST00000465399.5; ENST00000419606.5; ENST00000400771.7; ENST00000402096.5; ENST00000475195.5; ENST00000482507.5; ENST00000404914.8; ENST00000625810.2; ENST00000400772.6; ENST00000479554.5; ENST00000468018.5; ENST00000493618.5; ENST00000483778.5; ENST00000415107.5; ENST00000344376.9; ENST00000430617.6; ENST00000405546.7
External Link	RMBase: m6A_site_519045
mod ID: M6ASITE050846		Click to Show/Hide the Full List
mod site	chr2:241651214-241651215:+		[10]
Sequence	CCATAACTTGTGACTTGCAAACTTAAGGCGTTGTGTGTGTG
Motif Score	2.627720238
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000493618.5; ENST00000402096.5; ENST00000425239.5; ENST00000415107.5; ENST00000475195.5; ENST00000468018.5; ENST00000400772.6; ENST00000404914.8; ENST00000494465.5; ENST00000479554.5; ENST00000491867.5; ENST00000419606.5; ENST00000405546.7; ENST00000465399.5; ENST00000344376.9; ENST00000430617.6; ENST00000625810.2; ENST00000483778.5; ENST00000400771.7; ENST00000482507.5
External Link	RMBase: m6A_site_519046
mod ID: M6ASITE050847		Click to Show/Hide the Full List
mod site	chr2:241651252-241651253:+		[11]
Sequence	GTGTGTTTTTTTTCTTTTAAACAACCTCTAGAAAAGGACGA
Motif Score	2.20572619
Cell/Tissue List	MT4; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000625810.2; ENST00000494465.5; ENST00000400772.6; ENST00000405546.7; ENST00000491867.5; ENST00000344376.9; ENST00000419606.5; ENST00000465399.5; ENST00000483778.5; ENST00000479554.5; ENST00000425239.5; ENST00000402096.5; ENST00000404914.8; ENST00000475195.5; ENST00000493618.5; ENST00000430617.6; ENST00000400771.7; ENST00000415107.5; ENST00000482507.5; ENST00000468018.5
External Link	RMBase: m6A_site_519047
mod ID: M6ASITE050848		Click to Show/Hide the Full List
mod site	chr2:241651297-241651298:+		[11]
Sequence	TTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA
Motif Score	3.319380952
Cell/Tissue List	MT4; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000405546.7; ENST00000493618.5; ENST00000430617.6; ENST00000483778.5; ENST00000402096.5; ENST00000425239.5; ENST00000475195.5; ENST00000625810.2; ENST00000404914.8; ENST00000482507.5; ENST00000400771.7; ENST00000468018.5; ENST00000479554.5; ENST00000415107.5; ENST00000344376.9; ENST00000400772.6; ENST00000419606.5; ENST00000465399.5; ENST00000494465.5; ENST00000491867.5
External Link	RMBase: m6A_site_519048
mod ID: M6ASITE050849		Click to Show/Hide the Full List
mod site	chr2:241651307-241651308:+		[9]
Sequence	TGGCATCTAGACTTTGGTTTACATACAGGAAAAACTTTCCA
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000483778.5; ENST00000465399.5; ENST00000468018.5; ENST00000482507.5; ENST00000344376.9; ENST00000625810.2; ENST00000415107.5; ENST00000419606.5; ENST00000475195.5; ENST00000400772.6; ENST00000493618.5; ENST00000479554.5; ENST00000400771.7; ENST00000404914.8; ENST00000402096.5; ENST00000494465.5; ENST00000425239.5; ENST00000430617.6; ENST00000491867.5; ENST00000405546.7
External Link	RMBase: m6A_site_519049
mod ID: M6ASITE050851		Click to Show/Hide the Full List
mod site	chr2:241651320-241651321:+		[11]
Sequence	TTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGTAAGT
Motif Score	2.627720238
Cell/Tissue List	MT4; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000430617.6; ENST00000404914.8; ENST00000400771.7; ENST00000493618.5; ENST00000468018.5; ENST00000475195.5; ENST00000491867.5; ENST00000479554.5; ENST00000482507.5; ENST00000405546.7; ENST00000402096.5; ENST00000425239.5; ENST00000400772.6; ENST00000494465.5; ENST00000625810.2; ENST00000483778.5; ENST00000344376.9; ENST00000419606.5; ENST00000465399.5; ENST00000415107.5
External Link	RMBase: m6A_site_519050
mod ID: M6ASITE050852		Click to Show/Hide the Full List
mod site	chr2:241651927-241651928:+		[11]
Sequence	GGAGCTGGAAGGAGATGGGGACTGGTTCTCAGCCTTGCCTC
Motif Score	4.065041667
Cell/Tissue List	MT4; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000475195.5; ENST00000483778.5; ENST00000430617.6; ENST00000402096.5; ENST00000468018.5; ENST00000344376.9; ENST00000405546.7; ENST00000415107.5; ENST00000479554.5; ENST00000400771.7; ENST00000482507.5; ENST00000404914.8; ENST00000494465.5; ENST00000465399.5; ENST00000419606.5; ENST00000625810.2; ENST00000425239.5; ENST00000491867.5; ENST00000400772.6; ENST00000493618.5
External Link	RMBase: m6A_site_519051
mod ID: M6ASITE050853		Click to Show/Hide the Full List
mod site	chr2:241651961-241651962:+		[11]
Sequence	TTGCCTCTCACCGGCGGAGAACTGAGGCCGGAGGTGAGGGC
Motif Score	3.373380952
Cell/Tissue List	MT4; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000493618.5; ENST00000405546.7; ENST00000430617.6; ENST00000465399.5; ENST00000483778.5; ENST00000400771.7; ENST00000425239.5; ENST00000344376.9; ENST00000419606.5; ENST00000479554.5; ENST00000402096.5; ENST00000482507.5; ENST00000468018.5; ENST00000404914.8; ENST00000491867.5; ENST00000625810.2; ENST00000475195.5; ENST00000415107.5; ENST00000494465.5; ENST00000400772.6
External Link	RMBase: m6A_site_519052
mod ID: M6ASITE050854		Click to Show/Hide the Full List
mod site	chr2:241653516-241653517:+		[8]
Sequence	TGTCTGCCACGACAGGGGGGACAGGCCCCACCTCGGACACA
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000482507.5; ENST00000415107.5; ENST00000404914.8; ENST00000425239.5; ENST00000400771.7; ENST00000405546.7; ENST00000493618.5; ENST00000429899.1; ENST00000494465.5; ENST00000419606.5; ENST00000402096.5; ENST00000465399.5; ENST00000468018.5; ENST00000344376.9; ENST00000475195.5; ENST00000479554.5; ENST00000400772.6; ENST00000430617.6; ENST00000483778.5
External Link	RMBase: m6A_site_519053
mod ID: M6ASITE050855		Click to Show/Hide the Full List
mod site	chr2:241653532-241653533:+		[8]
Sequence	GGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEK293T; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000344376.9; ENST00000465399.5; ENST00000405546.7; ENST00000400772.6; ENST00000468018.5; ENST00000430617.6; ENST00000479554.5; ENST00000402096.5; ENST00000475195.5; ENST00000425239.5; ENST00000482507.5; ENST00000404914.8; ENST00000483778.5; ENST00000400771.7; ENST00000494465.5; ENST00000493618.5; ENST00000429899.1; ENST00000419606.5
External Link	RMBase: m6A_site_519054
mod ID: M6ASITE050856		Click to Show/Hide the Full List
mod site	chr2:241653563-241653564:+		[8]
Sequence	GGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000483778.5; ENST00000468018.5; ENST00000465399.5; ENST00000494465.5; ENST00000479554.5; ENST00000493618.5; ENST00000402096.5; ENST00000404914.8; ENST00000429899.1; ENST00000425239.5; ENST00000419606.5; ENST00000405546.7; ENST00000430617.6; ENST00000400771.7; ENST00000344376.9; ENST00000482507.5; ENST00000400772.6; ENST00000475195.5
External Link	RMBase: m6A_site_519055
mod ID: M6ASITE050857		Click to Show/Hide the Full List
mod site	chr2:241654556-241654557:+		[12]
Sequence	TTCCAATAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCA
Motif Score	3.643047619
Cell/Tissue List	HepG2; hESC-HEK293T; peripheral-blood; endometrial; NB4; MM6
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000419606.5; ENST00000425239.5; ENST00000405546.7; ENST00000344376.9; ENST00000468018.5; ENST00000402096.5; ENST00000430617.6; ENST00000475195.5; ENST00000483778.5; ENST00000404914.8; ENST00000482507.5; ENST00000400772.6; ENST00000400771.7; ENST00000465399.5; ENST00000494465.5; ENST00000479554.5; ENST00000429899.1; ENST00000493618.5
External Link	RMBase: m6A_site_519056
mod ID: M6ASITE050858		Click to Show/Hide the Full List
mod site	chr2:241654578-241654579:+		[13]
Sequence	ACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCA
Motif Score	2.897386905
Cell/Tissue List	HepG2; peripheral-blood; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000468018.5; ENST00000479554.5; ENST00000425239.5; ENST00000400771.7; ENST00000482507.5; ENST00000493618.5; ENST00000429899.1; ENST00000402096.5; ENST00000475195.5; ENST00000430617.6; ENST00000494465.5; ENST00000465399.5; ENST00000419606.5; ENST00000404914.8; ENST00000483778.5; ENST00000344376.9; ENST00000400772.6; ENST00000405546.7
External Link	RMBase: m6A_site_519057
mod ID: M6ASITE050859		Click to Show/Hide the Full List
mod site	chr2:241654620-241654621:+		[13]
Sequence	CGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACC
Motif Score	3.643047619
Cell/Tissue List	HepG2; peripheral-blood; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000482507.5; ENST00000404914.8; ENST00000493618.5; ENST00000400771.7; ENST00000402096.5; ENST00000483778.5; ENST00000405546.7; ENST00000425239.5; ENST00000344376.9; ENST00000400772.6; ENST00000419606.5; ENST00000475195.5; ENST00000479554.5; ENST00000468018.5; ENST00000429899.1; ENST00000465399.5; ENST00000494465.5; ENST00000430617.6
External Link	RMBase: m6A_site_519058
mod ID: M6ASITE050860		Click to Show/Hide the Full List
mod site	chr2:241654761-241654762:+		[14]
Sequence	TGTGGAGCAGGAGGCTGTAAACCTGTAAACACTGACCTCTG
Motif Score	2.185083333
Cell/Tissue List	GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000482507.5; ENST00000400771.7; ENST00000493618.5; ENST00000404914.8; ENST00000483778.5; ENST00000419606.5; ENST00000430617.6; ENST00000494465.5; ENST00000400772.6; ENST00000465399.5; ENST00000475195.5; ENST00000468018.5; ENST00000425239.5; ENST00000405546.7; ENST00000402096.5; ENST00000429899.1; ENST00000344376.9
External Link	RMBase: m6A_site_519059
mod ID: M6ASITE050862		Click to Show/Hide the Full List
mod site	chr2:241654769-241654770:+		[14]
Sequence	AGGAGGCTGTAAACCTGTAAACACTGACCTCTGACCATCTG
Motif Score	2.20572619
Cell/Tissue List	GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000405546.7; ENST00000419606.5; ENST00000344376.9; ENST00000400772.6; ENST00000404914.8; ENST00000494465.5; ENST00000468018.5; ENST00000425239.5; ENST00000482507.5; ENST00000475195.5; ENST00000430617.6; ENST00000465399.5; ENST00000483778.5; ENST00000493618.5; ENST00000402096.5; ENST00000400771.7; ENST00000429899.1
External Link	RMBase: m6A_site_519060
mod ID: M6ASITE050863		Click to Show/Hide the Full List
mod site	chr2:241654851-241654852:+		[15]
Sequence	CCCGTCCCACCCAGGCCCAGACCCTGGGCCTTGCCCTTCCT
Motif Score	2.876744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000465399.5; ENST00000468018.5; ENST00000402096.5; ENST00000493618.5; ENST00000400772.6; ENST00000404914.8; ENST00000430617.6; ENST00000344376.9; ENST00000494465.5; ENST00000483778.5; ENST00000405546.7; ENST00000429899.1; ENST00000400771.7; ENST00000425239.5; ENST00000419606.5; ENST00000475195.5; ENST00000482507.5
External Link	RMBase: m6A_site_519061
mod ID: M6ASITE050864		Click to Show/Hide the Full List
mod site	chr2:241655321-241655322:+		[9]
Sequence	AGGCCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000425239.5; ENST00000465399.5; ENST00000344376.9; ENST00000483778.5; ENST00000402096.5; ENST00000468018.5; ENST00000494465.5; ENST00000430617.6; ENST00000400771.7; ENST00000404914.8; ENST00000405546.7; ENST00000482507.5; ENST00000493618.5; ENST00000400772.6; ENST00000429899.1
External Link	RMBase: m6A_site_519062
mod ID: M6ASITE050865		Click to Show/Hide the Full List
mod site	chr2:241659148-241659149:+		[9]
Sequence	GTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000482507.5; ENST00000425239.5; ENST00000468018.5; ENST00000494465.5; ENST00000429899.1; ENST00000483778.5; ENST00000344376.9; ENST00000430617.6; ENST00000493618.5; ENST00000404914.8; ENST00000405546.7; ENST00000402096.5; ENST00000400771.7
External Link	RMBase: m6A_site_519063
mod ID: M6ASITE050866		Click to Show/Hide the Full List
mod site	chr2:241659163-241659164:+		[9]
Sequence	GGTCCACATTGCAATGGACAACACTGTTGTGATGGAGGAAA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000405546.7; ENST00000494465.5; ENST00000425239.5; ENST00000430617.6; ENST00000429899.1; ENST00000404914.8; ENST00000468018.5; ENST00000344376.9; ENST00000483778.5; ENST00000493618.5; ENST00000482507.5; ENST00000402096.5; ENST00000400771.7
External Link	RMBase: m6A_site_519064
mod ID: M6ASITE050867		Click to Show/Hide the Full List
mod site	chr2:241659643-241659644:+		[8]
Sequence	TCTGCTGCAACCCTGAAGGAACCTGGGCGTGGCAACATTTA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000494465.5; ENST00000400771.7; ENST00000429899.1; ENST00000404914.8; ENST00000482507.5; ENST00000402096.5; ENST00000344376.9; ENST00000483778.5; ENST00000405546.7
External Link	RMBase: m6A_site_519065
mod ID: M6ASITE050868		Click to Show/Hide the Full List
mod site	chr2:241659678-241659679:+		[8]
Sequence	CATTTACATCTAGGAGGAAAACTGTGGCTCAGTTTTAACAA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000494465.5; ENST00000429899.1; ENST00000482507.5; ENST00000483778.5; ENST00000402096.5; ENST00000344376.9; ENST00000405546.7; ENST00000404914.8; ENST00000400771.7
External Link	RMBase: m6A_site_519066
mod ID: M6ASITE050869		Click to Show/Hide the Full List
mod site	chr2:241659761-241659762:+
Sequence	ATGATGTAGCCAAGCTGAGAACTCTTAAAAATGCCTCATTG
Motif Score	3.373380952
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000344376.9; ENST00000404914.8; ENST00000402096.5; ENST00000400771.7; ENST00000429899.1; ENST00000482507.5; ENST00000483778.5; ENST00000494465.5; ENST00000405546.7
External Link	RMBase: m6A_site_519067
mod ID: M6ASITE050870		Click to Show/Hide the Full List
mod site	chr2:241666658-241666659:+		[8]
Sequence	TTCTAGGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000404914.8; ENST00000429899.1; ENST00000344376.9; ENST00000482507.5; ENST00000494465.5; ENST00000402096.5; ENST00000400771.7; ENST00000428861.1; ENST00000405546.7
External Link	RMBase: m6A_site_519068
mod ID: M6ASITE050871		Click to Show/Hide the Full List
mod site	chr2:241666746-241666747:+		[16]
Sequence	TGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGAC
Motif Score	2.173910714
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000428861.1; ENST00000402096.5; ENST00000405546.7; ENST00000482507.5; ENST00000404914.8; ENST00000344376.9; ENST00000400771.7; ENST00000494465.5; ENST00000429899.1
External Link	RMBase: m6A_site_519069
mod ID: M6ASITE050873		Click to Show/Hide the Full List
mod site	chr2:241666765-241666766:+		[8]
Sequence	AACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000405546.7; ENST00000494465.5; ENST00000482507.5; ENST00000400771.7; ENST00000404914.8; ENST00000429899.1; ENST00000344376.9; ENST00000428861.1; ENST00000402096.5
External Link	RMBase: m6A_site_519070
mod ID: M6ASITE050874		Click to Show/Hide the Full List
mod site	chr2:241666806-241666807:+		[8]
Sequence	CCTGCGCCTGGGGCTCACGGACATCAACGAGGCCTACGTGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; peripheral-blood
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000428861.1; ENST00000494465.5; ENST00000405546.7; ENST00000404914.8; ENST00000344376.9; ENST00000402096.5; ENST00000400771.7; ENST00000482507.5
External Link	RMBase: m6A_site_519071
mod ID: M6ASITE050875		Click to Show/Hide the Full List
mod site	chr2:241668566-241668567:+		[16]
Sequence	GCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGG
Motif Score	2.053113095
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000404914.8; ENST00000428861.1; ENST00000475693.1; ENST00000405546.7; ENST00000494465.5; ENST00000460211.5; ENST00000402096.5; ENST00000482507.5; ENST00000479941.1; ENST00000344376.9
External Link	RMBase: m6A_site_519072
mod ID: M6ASITE050876		Click to Show/Hide the Full List
mod site	chr2:241668840-241668841:+		[17]
Sequence	TGAAGGGTATAAGAGCCGGAACTGTGTCCTTGCACCCTCAC
Motif Score	3.373380952
Cell/Tissue List	Jurkat
Seq Type List	m6A-seq
Transcript ID List	ENST00000428861.1; ENST00000479941.1; ENST00000460211.5; ENST00000405546.7; ENST00000344376.9; ENST00000494465.5; ENST00000475693.1; ENST00000402096.5; ENST00000482507.5; ENST00000404914.8
External Link	RMBase: m6A_site_519073
mod ID: M6ASITE050877		Click to Show/Hide the Full List
mod site	chr2:241671367-241671368:+		[9]
Sequence	CTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000494132.1; ENST00000404914.8; ENST00000494465.5; ENST00000405546.7; ENST00000475693.1; ENST00000482507.5; ENST00000344376.9; ENST00000402096.5; ENST00000460211.5
External Link	RMBase: m6A_site_519074
mod ID: M6ASITE050878		Click to Show/Hide the Full List
mod site	chr2:241671546-241671547:+		[8]
Sequence	GGCAGTGGTTCGCCTGTGAGACCAGGTATGGAGTGGAGCGT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000460211.5; ENST00000482507.5; ENST00000494465.5; ENST00000494132.1; ENST00000405546.7; ENST00000402096.5; ENST00000344376.9; ENST00000475693.1; ENST00000404914.8
External Link	RMBase: m6A_site_519075
mod ID: M6ASITE050879		Click to Show/Hide the Full List
mod site	chr2:241671600-241671601:+		[8]
Sequence	CTTGCGCCCAGCAGCCCAGGACCCACCTCGTCTTCCCCACC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000344376.9; ENST00000482507.5; ENST00000402096.5; ENST00000494465.5; ENST00000475693.1; ENST00000404914.8; ENST00000494132.1; ENST00000405546.7
External Link	RMBase: m6A_site_519076
mod ID: M6ASITE050880		Click to Show/Hide the Full List
mod site	chr2:241671688-241671689:+		[8]
Sequence	TCCTCAGGGGTCTGGAGCAGACAGAACATGCAGGCTCTGTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; MM6; Jurkat; CD4T; peripheral-blood; HEK293T; HEK293A-TOA; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000482507.5; ENST00000494465.5; ENST00000494132.1; ENST00000344376.9; ENST00000475693.1; ENST00000402096.5; ENST00000405546.7; ENST00000404914.8
External Link	RMBase: m6A_site_519077
mod ID: M6ASITE050881		Click to Show/Hide the Full List
mod site	chr2:241671693-241671694:+		[8]
Sequence	AGGGGTCTGGAGCAGACAGAACATGCAGGCTCTGTGGTGAC
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; MM6; Jurkat; CD4T; peripheral-blood; HEK293T; HEK293A-TOA; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000494465.5; ENST00000402096.5; ENST00000405546.7; ENST00000482507.5; ENST00000404914.8; ENST00000475693.1; ENST00000494132.1; ENST00000344376.9
External Link	RMBase: m6A_site_519078
mod ID: M6ASITE050882		Click to Show/Hide the Full List
mod site	chr2:241671731-241671732:+		[8]
Sequence	GACGCAGTCCTGGGTGGGGGACTGGTTCACTTGGGCACCAC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; MM6; Jurkat; CD4T; peripheral-blood; HEK293T; HEK293A-TOA; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000404914.8; ENST00000475693.1; ENST00000405546.7; ENST00000494132.1; ENST00000402096.5; ENST00000494465.5; ENST00000344376.9; ENST00000482507.5
External Link	RMBase: m6A_site_519079
mod ID: M6ASITE050884		Click to Show/Hide the Full List
mod site	chr2:241671770-241671771:+		[8]
Sequence	ACTGGCCATGGGTGGCGTAGACCCCTCGGACCATGGCCAGC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; MM6; Jurkat; CD4T; peripheral-blood; HEK293T; HEK293A-TOA; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000475693.1; ENST00000482507.5; ENST00000494465.5; ENST00000404914.8; ENST00000494132.1; ENST00000405546.7; ENST00000402096.5; ENST00000344376.9
External Link	RMBase: m6A_site_519080
mod ID: M6ASITE050885		Click to Show/Hide the Full List
mod site	chr2:241671779-241671780:+		[8]
Sequence	GGGTGGCGTAGACCCCTCGGACCATGGCCAGCGTGCCGCAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; MM6; Jurkat; CD4T; peripheral-blood; HEK293T; HEK293A-TOA; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000404914.8; ENST00000344376.9; ENST00000494132.1; ENST00000494465.5; ENST00000402096.5; ENST00000475693.1; ENST00000482507.5; ENST00000405546.7
External Link	RMBase: m6A_site_519081
mod ID: M6ASITE050886		Click to Show/Hide the Full List
mod site	chr2:241671874-241671875:+		[8]
Sequence	TCTCTGTCTCCCTGTGGGAAACTCTACAAACAAGGCAATGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; MM6; Jurkat; CD4T; HEK293A-TOA; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000494132.1; ENST00000404914.8; ENST00000405546.7; ENST00000344376.9; ENST00000494465.5; ENST00000475693.1; ENST00000482507.5; ENST00000402096.5
External Link	RMBase: m6A_site_519082
mod ID: M6ASITE050887		Click to Show/Hide the Full List
mod site	chr2:241671883-241671884:+		[8]
Sequence	CCCTGTGGGAAACTCTACAAACAAGGCAATGGCAATGGAAC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; MM6; Jurkat; CD4T; HEK293A-TOA; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475693.1; ENST00000494465.5; ENST00000482507.5; ENST00000494132.1; ENST00000402096.5; ENST00000404914.8; ENST00000344376.9; ENST00000405546.7
External Link	RMBase: m6A_site_519083
mod ID: M6ASITE050888		Click to Show/Hide the Full List
mod site	chr2:241671902-241671903:+		[8]
Sequence	AACAAGGCAATGGCAATGGAACCACTCCTGATGACCACGAG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; MM6; Jurkat; CD4T; HEK293A-TOA; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405546.7; ENST00000475693.1; ENST00000402096.5; ENST00000494132.1; ENST00000482507.5; ENST00000404914.8; ENST00000494465.5; ENST00000344376.9
External Link	RMBase: m6A_site_519084
mod ID: M6ASITE050889		Click to Show/Hide the Full List
mod site	chr2:241671936-241671937:+		[8]
Sequence	CCACGAGGGTCAGACGCGGGACAGAGGCCCCTCAGGCCTGA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; MM6; Jurkat; HEK293A-TOA; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405546.7; ENST00000344376.9; ENST00000404914.8; ENST00000494465.5; ENST00000475693.1; ENST00000402096.5; ENST00000482507.5
External Link	RMBase: m6A_site_519085
mod ID: M6ASITE050890		Click to Show/Hide the Full List
mod site	chr2:241672049-241672050:+		[8]
Sequence	CAGGTCTGCACAACCCCCGGACCTGTTCACACCCGCATGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475693.1; ENST00000404914.8; ENST00000344376.9; ENST00000402096.5; ENST00000405546.7; ENST00000482507.5; ENST00000494465.5
External Link	RMBase: m6A_site_519086
mod ID: M6ASITE050891		Click to Show/Hide the Full List
mod site	chr2:241672071-241672072:+
Sequence	CTGTTCACACCCGCATGGGGACAGCTGTCTGTGGGCTGCAG
Motif Score	3.643047619
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000494465.5; ENST00000475693.1; ENST00000404914.8; ENST00000402096.5; ENST00000405546.7; ENST00000344376.9; ENST00000482507.5
External Link	RMBase: m6A_site_519087
mod ID: M6ASITE050892		Click to Show/Hide the Full List
mod site	chr2:241672241-241672242:+		[8]
Sequence	CTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; GM12878; MM6; Huh7; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000494465.5; ENST00000404914.8; ENST00000344376.9; ENST00000405546.7; ENST00000482507.5; ENST00000475693.1; ENST00000402096.5
External Link	RMBase: m6A_site_519088
mod ID: M6ASITE050893		Click to Show/Hide the Full List
mod site	chr2:241672403-241672404:+		[8]
Sequence	GCCACCCGCTGTGCTCGTGGACTGAGGCTGCGCTGCCCGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000402096.5; ENST00000344376.9; ENST00000404914.8; ENST00000405546.7; ENST00000475693.1; ENST00000482507.5; ENST00000494465.5
External Link	RMBase: m6A_site_519089
mod ID: M6ASITE050895		Click to Show/Hide the Full List
mod site	chr2:241672431-241672432:+		[18]
Sequence	TGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCC
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475693.1; ENST00000482507.5; ENST00000344376.9; ENST00000402096.5; ENST00000404914.8; ENST00000405546.7; ENST00000494465.5
External Link	RMBase: m6A_site_519090
mod ID: M6ASITE050896		Click to Show/Hide the Full List
mod site	chr2:241672446-241672447:+		[8]
Sequence	GCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000344376.9; ENST00000494465.5; ENST00000402096.5; ENST00000405546.7; ENST00000475693.1; ENST00000482507.5; ENST00000404914.8
External Link	RMBase: m6A_site_519091
mod ID: M6ASITE050897		Click to Show/Hide the Full List
mod site	chr2:241672528-241672529:+		[9]
Sequence	GCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000494465.5; ENST00000482507.5; ENST00000344376.9; ENST00000475693.1; ENST00000405546.7; ENST00000404914.8; ENST00000402096.5
External Link	RMBase: m6A_site_519092
mod ID: M6ASITE050898		Click to Show/Hide the Full List
mod site	chr2:241672630-241672631:+		[8]
Sequence	GTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; H1A; H1B; GM12878; LCLs; MM6; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000404914.8; ENST00000482507.5; ENST00000405546.7; ENST00000475693.1
External Link	RMBase: m6A_site_519093
mod ID: M6ASITE050899		Click to Show/Hide the Full List
mod site	chr2:241672636-241672637:+		[8]
Sequence	TTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; GM12878; LCLs; MM6; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475693.1; ENST00000404914.8; ENST00000405546.7
External Link	RMBase: m6A_site_519094
mod ID: M6ASITE050900		Click to Show/Hide the Full List
mod site	chr2:241672677-241672678:+		[8]
Sequence	CTGAGTCAGAGTCTCAGAAGACCTGTGCAGGCTGGCGTGAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; GM12878; LCLs; MM6; Jurkat; CD4T; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000404914.8; ENST00000405546.7; ENST00000475693.1
External Link	RMBase: m6A_site_519095
mod ID: M6ASITE050901		Click to Show/Hide the Full List
mod site	chr2:241672734-241672735:+		[8]
Sequence	CTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405546.7; ENST00000475693.1; ENST00000404914.8
External Link	RMBase: m6A_site_519096
mod ID: M6ASITE050902		Click to Show/Hide the Full List
mod site	chr2:241672893-241672894:+		[8]
Sequence	AGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405546.7; ENST00000475693.1; ENST00000404914.8
External Link	RMBase: m6A_site_519097
mod ID: M6ASITE050903		Click to Show/Hide the Full List
mod site	chr2:241672915-241672916:+		[8]
Sequence	CTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; GM12878; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000404914.8; ENST00000405546.7; ENST00000475693.1
External Link	RMBase: m6A_site_519098
mod ID: M6ASITE050904		Click to Show/Hide the Full List
mod site	chr2:241673189-241673190:+		[12]
Sequence	TTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTGT
Motif Score	2.185083333
Cell/Tissue List	HepG2; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000405546.7; ENST00000475693.1; ENST00000404914.8
External Link	RMBase: m6A_site_519099
mod ID: M6ASITE050906		Click to Show/Hide the Full List
mod site	chr2:241673221-241673222:+		[13]
Sequence	TTGTGGTGTGTGGTGGGCAGACACCACAGGGTGGCATCACC
Motif Score	2.897386905
Cell/Tissue List	HepG2; HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000404914.8; ENST00000475693.1; ENST00000405546.7
External Link	RMBase: m6A_site_519100
mod ID: M6ASITE050907		Click to Show/Hide the Full List
mod site	chr2:241673258-241673259:+		[8]
Sequence	CACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000405546.7; ENST00000475693.1; ENST00000404914.8
External Link	RMBase: m6A_site_519101
mod ID: M6ASITE050908		Click to Show/Hide the Full List
mod site	chr2:241673392-241673393:+		[8]
Sequence	TGCCCCACTAGGAAATGTAAACAGGAGGGCTTGGGGAGCGT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000404914.8; ENST00000475693.1; ENST00000405546.7
External Link	RMBase: m6A_site_519102
mod ID: M6ASITE050909		Click to Show/Hide the Full List
mod site	chr2:241673453-241673454:+		[8]
Sequence	GCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA; TREX; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000404914.8; ENST00000475693.1; ENST00000405546.7
External Link	RMBase: m6A_site_519103
mod ID: M6ASITE050910		Click to Show/Hide the Full List
mod site	chr2:241673518-241673519:+		[8]
Sequence	TCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; H1B; A549; MM6; Jurkat; HEK293A-TOA; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000404914.8; ENST00000405546.7; ENST00000475693.1
External Link	RMBase: m6A_site_519104
mod ID: M6ASITE050911		Click to Show/Hide the Full List
mod site	chr2:241673554-241673555:+		[8]
Sequence	GGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCCCAAGCA
Motif Score	3.643047619
Cell/Tissue List	HeLa; H1B; H1A; A549; MM6; Jurkat; HEK293A-TOA; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000404914.8; ENST00000475693.1; ENST00000405546.7
External Link	RMBase: m6A_site_519105
mod ID: M6ASITE050912		Click to Show/Hide the Full List
mod site	chr2:241673581-241673582:+		[8]
Sequence	CAGCCCCCCAAGCATTGAAGACATAGTGTATTTCCTCGTAT
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T; H1B; MM6; Jurkat; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000475693.1; ENST00000404914.8; ENST00000405546.7
External Link	RMBase: m6A_site_519106
mod ID: M6ASITE050913		Click to Show/Hide the Full List
mod site	chr2:241673728-241673729:+		[8]
Sequence	CTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000404914.8; ENST00000405546.7; ENST00000475693.1
External Link	RMBase: m6A_site_519107
mod ID: M6ASITE050914		Click to Show/Hide the Full List
mod site	chr2:241673852-241673853:+		[9]
Sequence	ATAATAAGTTTCAGTAGAAAACAAACCTTGTGTCTATTTTT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000405546.7; ENST00000404914.8
External Link	RMBase: m6A_site_519108

N7-methylguanosine (m7G)

In total 1 m6A sequence/site(s) in this target gene
mod ID: m7GSITE000078		Click to Show/Hide the Full List
mod site	chr2:241672262-241672263:+		[19]
Sequence	CTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGT
Cell/Tissue List	A549; HeLa; HepG2
Seq Type List	BoRed-seq&m7G-RIP-seq; m7G-seq
Transcript ID List	ENST00000405546.7; ENST00000475693.1; ENST00000482507.5; ENST00000404914.8; ENST00000402096.5; ENST00000344376.9; ENST00000494465.5
External Link	RMBase: m7G_site_557

Ref 1	Clinical pipeline report, company report or official report of Progenics Pharmaceuticals Serometrix.
Ref 2	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 3	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 4	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 5	Base-Resolution Mapping Reveals Distinct m(1)A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts. Mol Cell. 2017 Dec 7;68(5):993-1005.e9. doi: 10.1016/j.molcel.2017.10.019. Epub 2017 Nov 5.
Ref 6	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 7	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 8	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 9	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 10	R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
Ref 11	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 12	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 13	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 14	m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 Apr 10;31(4):591-606.e6. doi: 10.1016/j.ccell.2017.02.013. Epub 2017 Mar 23.
Ref 15	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 16	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 17	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Elife. 2016 Jul 2;5:e15528. doi: 10.7554/eLife.15528.
Ref 18	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 19	METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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