m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00597)

Target Name	Collagen alpha-1 (III) chain (COL3A1)
Gene Name	COL3A1
Chromosomal Location	2q32.2
Family	Fibrillar collagen family
Function	Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. Click to Show/Hide
Gene ID	1281
Uniprot ID	CO3A1_HUMAN
HGNC ID	HGNC:2201
KEGG ID	hsa:1281

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

COL3A1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	Caco-2 cell line	Homo sapiens
Treatment: shMETTL3 Caco-2 cells Control: shNTC Caco-2 cells		GSE167075
Regulation		logFC: 2.13E+00 p-value: 6.01E-268
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between COL3A1 and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 3.39E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	METTL3 could down-regulate the expression of Collagen alpha-1 (III) chain (COL3A1) by increasing its m6A methylation, ultimately inhibiting the metastasis of TNBC cells.
Target Regulation	Down regulation
Responsed Disease	Breast cancer		ICD-11: 2C60	Disease Info
In-vitro Model	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
In-vitro Model	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062

Breast cancer [ICD-11: 2C60]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	METTL3 could down-regulate the expression of Collagen alpha-1 (III) chain (COL3A1) by increasing its m6A methylation, ultimately inhibiting the metastasis of TNBC cells.
Responsed Disease	Breast cancer [ICD-11: 2C60]
Target Regulator	Methyltransferase-like 3 (METTL3)		WRITER	Regulator Info
Target Regulation	Down regulation
In-vitro Model	MDA-MB-468	Breast adenocarcinoma	Homo sapiens	CVCL_0419
In-vitro Model	MDA-MB-231	Breast adenocarcinoma	Homo sapiens	CVCL_0062

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

DNA modification

m6A Regulator: YTH domain-containing family protein 1 (YTHDF1)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT02003		Crosstalk Info
Epigenetic Regulator	Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target	Suppressor of cytokine signaling 3 (SOCS3)
Crosstalk relationship	DNA modification → m6A
Disease	Hepatic fibrosis/cirrhosis	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00597)

Collagen alpha-1 (III) chain (COL3A1)

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002441		Click to Show/Hide the Full List
mod site	chr2:189006958-189006959:+		[3]
Sequence	CCCTGCTGGCCCTGCTGGTGCTCCCGGTCCTGCTGGTTCCC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m5C_site_27603

N6-methyladenosine (m6A)

In total 89 m6A sequence/site(s) in this target gene
mod ID: M6ASITE048922		Click to Show/Hide the Full List
mod site	chr2:188984946-188984947:+		[4]
Sequence	GAATGTTGTGCAGTTTGCCCACAGCCTCCAACTGCTGTGAG
Motif Score	2.053113095
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000470167.1
External Link	RMBase: m6A_site_503272
mod ID: M6ASITE048923		Click to Show/Hide the Full List
mod site	chr2:188985222-188985223:+		[5]
Sequence	CGCCCTCCTAATGGTCAAGGACCTCAAGGCCCCAAGGGAGA
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503273
mod ID: M6ASITE048924		Click to Show/Hide the Full List
mod site	chr2:188985711-188985712:+		[5]
Sequence	GGTGACCCTGGTATTCCAGGACAACCAGGGTCCCCTGGTTC
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503274
mod ID: M6ASITE048925		Click to Show/Hide the Full List
mod site	chr2:188987114-188987115:+		[5]
Sequence	TCTGGAGTAGCAGTAGGAGGACTCGCAGGCTATCCTGGACC
Motif Score	4.065041667
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503275
mod ID: M6ASITE048926		Click to Show/Hide the Full List
mod site	chr2:188987132-188987133:+		[5]
Sequence	GGACTCGCAGGCTATCCTGGACCAGCTGTACGTACAAATGT
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503276
mod ID: M6ASITE048927		Click to Show/Hide the Full List
mod site	chr2:188988609-188988610:+		[5]
Sequence	GGATCTCCAGGATACCAAGGACCCCCTGGTGAACCTGGGCA
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503277
mod ID: M6ASITE048928		Click to Show/Hide the Full List
mod site	chr2:188988621-188988622:+		[5]
Sequence	TACCAAGGACCCCCTGGTGAACCTGGGCAAGCTGGTCCTTC
Motif Score	2.930744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503278
mod ID: M6ASITE048929		Click to Show/Hide the Full List
mod site	chr2:188989406-188989407:+		[5]
Sequence	TATTTTCAGGGCCCTCCAGGACCTCCTGGTGCTATAGGTCC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503279
mod ID: M6ASITE048930		Click to Show/Hide the Full List
mod site	chr2:188990109-188990110:+		[5]
Sequence	ACCTAGGGAGAATCAGGTAGACCCGGACGACCTGGAGAGCG
Motif Score	2.876744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503280
mod ID: M6ASITE048931		Click to Show/Hide the Full List
mod site	chr2:188990142-188990143:+		[5]
Sequence	GGAGAGCGAGGATTGCCTGGACCTCCAGTGAGTCTTCAGCA
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503281
mod ID: M6ASITE048932		Click to Show/Hide the Full List
mod site	chr2:188990353-188990354:+		[5]
Sequence	GGATTCCCTGGTATGAAAGGACACAGAGTAAGTAGAGTTTC
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503282
mod ID: M6ASITE048933		Click to Show/Hide the Full List
mod site	chr2:188991036-188991037:+		[5]
Sequence	GAAATGGAGAAAAGGGTGAAACAGGTGCTCCTGGATTAAAG
Motif Score	2.20572619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503283
mod ID: M6ASITE048934		Click to Show/Hide the Full List
mod site	chr2:188991524-188991525:+		[5]
Sequence	GGCGAAAATGGAGCTCCTGGACCCATGGTAATTATGTTTCT
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503284
mod ID: M6ASITE048935		Click to Show/Hide the Full List
mod site	chr2:188991706-188991707:+		[5]
Sequence	GGTGAGCGAGGACGGCCAGGACTTCCTGGGGCTGCAGTGAG
Motif Score	4.065041667
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000450867.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503285
mod ID: M6ASITE048936		Click to Show/Hide the Full List
mod site	chr2:188992907-188992908:+		[5]
Sequence	GCCCTCCTGGTCCTCCTGGAACTGCCGGATTCCCTGGATCC
Motif Score	3.373380952
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000450867.1; ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503286
mod ID: M6ASITE048937		Click to Show/Hide the Full List
mod site	chr2:188993371-188993372:+		[5]
Sequence	TACCATTAGGGTGAAGTTGGACCTGCAGGGTCTCCTGGTTC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000450867.1
External Link	RMBase: m6A_site_503287
mod ID: M6ASITE048938		Click to Show/Hide the Full List
mod site	chr2:188993407-188993408:+		[5]
Sequence	GGTTCAAATGGTGCCCCTGGACAAAGAGGAGAACCTGGACC
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000450867.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503288
mod ID: M6ASITE048939		Click to Show/Hide the Full List
mod site	chr2:188993419-188993420:+		[5]
Sequence	GCCCCTGGACAAAGAGGAGAACCTGGACCTCAGGGACACGC
Motif Score	2.930744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000450867.1; ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503289
mod ID: M6ASITE048940		Click to Show/Hide the Full List
mod site	chr2:188993425-188993426:+		[5]
Sequence	GGACAAAGAGGAGAACCTGGACCTCAGGGACACGCTGGTGC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000450867.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503290
mod ID: M6ASITE048941		Click to Show/Hide the Full List
mod site	chr2:188993434-188993435:+		[5]
Sequence	GGAGAACCTGGACCTCAGGGACACGCTGGTGCTCAAGGTCC
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000450867.1; ENST00000317840.9
External Link	RMBase: m6A_site_503291
mod ID: M6ASITE048942		Click to Show/Hide the Full List
mod site	chr2:188994262-188994263:+		[5]
Sequence	GGCATTCCTGGAGCTCCTGGACTGATGGGAGCCCGGGGTCC
Motif Score	4.065041667
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000450867.1
External Link	RMBase: m6A_site_503292
mod ID: M6ASITE048943		Click to Show/Hide the Full List
mod site	chr2:188994289-188994290:+		[5]
Sequence	GGAGCCCGGGGTCCTCCAGGACCAGCCGGTGCTAATGGTGC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9; ENST00000450867.1
External Link	RMBase: m6A_site_503293
mod ID: M6ASITE048944		Click to Show/Hide the Full List
mod site	chr2:188994316-188994317:+		[5]
Sequence	GGTGCTAATGGTGCTCCTGGACTGCGAGGTGGTGCAGTAAG
Motif Score	4.065041667
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503294
mod ID: M6ASITE048945		Click to Show/Hide the Full List
mod site	chr2:188994578-188994579:+		[5]
Sequence	GGTGCCAAAGGAGAGCCCGGACCACGTGGTGAACGCGTAAG
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503295
mod ID: M6ASITE048946		Click to Show/Hide the Full List
mod site	chr2:188994791-188994792:+		[5]
Sequence	AAGGATGGATCACCTGGAGAACCTGGTGCAAATGGGCTTCC
Motif Score	2.930744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503296
mod ID: M6ASITE048947		Click to Show/Hide the Full List
mod site	chr2:188995065-188995066:+		[6]
Sequence	GGTGCCCCTGGGTTCCGAGGACCTGCTGGACCAAATGGCAT
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503297
mod ID: M6ASITE048948		Click to Show/Hide the Full List
mod site	chr2:188995074-188995075:+		[6]
Sequence	GGGTTCCGAGGACCTGCTGGACCAAATGGCATCCCAGGAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503298
mod ID: M6ASITE048949		Click to Show/Hide the Full List
mod site	chr2:188995750-188995751:+		[6]
Sequence	CCCAGAGGAGCTGCTGGAGAACCTGGCAGAGATGGCGTCCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503299
mod ID: M6ASITE048951		Click to Show/Hide the Full List
mod site	chr2:188996147-188996148:+		[6]
Sequence	ATGCCCGGAAGTCCAGGAGGACCAGGAAGTGATGGGAAACC
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503300
mod ID: M6ASITE048952		Click to Show/Hide the Full List
mod site	chr2:188996165-188996166:+		[6]
Sequence	GGACCAGGAAGTGATGGGAAACCAGGGCCTCCCGTATGTAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503301
mod ID: M6ASITE048953		Click to Show/Hide the Full List
mod site	chr2:188997205-188997206:+		[5]
Sequence	GAACGAGGTGGCCCTGGAGGACCTGGCCCTCAGGTACGTAG
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503302
mod ID: M6ASITE048954		Click to Show/Hide the Full List
mod site	chr2:188997359-188997360:+		[5]
Sequence	CTCCTGGAAAGAATGGTGAAACTGGACCTCAGGGACCCCCA
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503303
mod ID: M6ASITE048955		Click to Show/Hide the Full List
mod site	chr2:188997364-188997365:+		[5]
Sequence	GGAAAGAATGGTGAAACTGGACCTCAGGGACCCCCAGGGCC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503304
mod ID: M6ASITE048956		Click to Show/Hide the Full List
mod site	chr2:188997373-188997374:+		[5]
Sequence	GGTGAAACTGGACCTCAGGGACCCCCAGGGCCTACTGTAAG
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503305
mod ID: M6ASITE048957		Click to Show/Hide the Full List
mod site	chr2:188997721-188997722:+		[5]
Sequence	GCCTGGTGGTGACAAAGGAGACACAGGACCCCCTGGTCCAC
Motif Score	2.897386905
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503306
mod ID: M6ASITE048958		Click to Show/Hide the Full List
mod site	chr2:188997728-188997729:+		[5]
Sequence	GGTGACAAAGGAGACACAGGACCCCCTGGTCCACAAGGATT
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503307
mod ID: M6ASITE048959		Click to Show/Hide the Full List
mod site	chr2:188998306-188998307:+		[6]
Sequence	CCTCCAGGAGAAAATGGAAAACCTGGGGAACCAGTAAGTTA
Motif Score	2.185083333
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503308
mod ID: M6ASITE048960		Click to Show/Hide the Full List
mod site	chr2:188998315-188998316:+		[6]
Sequence	GAAAATGGAAAACCTGGGGAACCAGTAAGTTACGTTTCATT
Motif Score	2.930744048
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503309
mod ID: M6ASITE048961		Click to Show/Hide the Full List
mod site	chr2:188999313-188999314:+		[6]
Sequence	GGTGCCCCTGGTGAACGTGGACCTCCTGGATTGGCAGGGGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503310
mod ID: M6ASITE048962		Click to Show/Hide the Full List
mod site	chr2:188999340-188999341:+		[6]
Sequence	GGATTGGCAGGGGCCCCAGGACTTAGAGGTGGAGCTGGTCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503311
mod ID: M6ASITE048963		Click to Show/Hide the Full List
mod site	chr2:188999846-188999847:+		[6]
Sequence	GCTTTTATTTGACAGGGTGAACCAGGCGGTCCAGGTGCTGA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503312
mod ID: M6ASITE048964		Click to Show/Hide the Full List
mod site	chr2:189001555-189001556:+		[5]
Sequence	GGTGAAGGTGGTGCCCCCGGACTTCCAGGTATAGCTGGACC
Motif Score	4.065041667
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503313
mod ID: M6ASITE048965		Click to Show/Hide the Full List
mod site	chr2:189001573-189001574:+		[5]
Sequence	GGACTTCCAGGTATAGCTGGACCTCGTGGTAGCCCTGTAAG
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503314
mod ID: M6ASITE048966		Click to Show/Hide the Full List
mod site	chr2:189002312-189002313:+		[5]
Sequence	TTCAGGGTGAGAGAGGTGAAACTGGCCCTCCAGGACCTGCT
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503315
mod ID: M6ASITE048967		Click to Show/Hide the Full List
mod site	chr2:189002326-189002327:+		[5]
Sequence	GGTGAAACTGGCCCTCCAGGACCTGCTGGTTTCCCTGGTGC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503316
mod ID: M6ASITE048968		Click to Show/Hide the Full List
mod site	chr2:189002956-189002957:+		[5]
Sequence	TGTTGTTGTTGCATGTAGGGACAGAATGGTGAACCTGGTGG
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503317
mod ID: M6ASITE048969		Click to Show/Hide the Full List
mod site	chr2:189002968-189002969:+		[5]
Sequence	ATGTAGGGACAGAATGGTGAACCTGGTGGTAAAGGAGAAAG
Motif Score	2.930744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503318
mod ID: M6ASITE048970		Click to Show/Hide the Full List
mod site	chr2:189003037-189003038:+		[5]
Sequence	GGCCCTCCTGGAGTTGCAGGACCCCCTGGAGGTTCTGGACC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503319
mod ID: M6ASITE048971		Click to Show/Hide the Full List
mod site	chr2:189003055-189003056:+		[5]
Sequence	GGACCCCCTGGAGGTTCTGGACCTGCTGTAAGTTCCTTCCT
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503320
mod ID: M6ASITE048972		Click to Show/Hide the Full List
mod site	chr2:189003460-189003461:+		[5]
Sequence	GAACGTGGCAGTCCTGGTGGACCTGTAAGTATTGATCCTCT
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000467886.1; ENST00000317840.9
External Link	RMBase: m6A_site_503321
mod ID: M6ASITE048973		Click to Show/Hide the Full List
mod site	chr2:189003858-189003859:+		[5]
Sequence	ATGTATGTATAGGATGAGAAACTTACACATTGCTACTTATT
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000467886.1
External Link	RMBase: m6A_site_503322
mod ID: M6ASITE048974		Click to Show/Hide the Full List
mod site	chr2:189003992-189003993:+		[5]
Sequence	TATTTGTAGGGTAACCCAGGACCCCCAGGTCCCAGCGGTTC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503323
mod ID: M6ASITE048975		Click to Show/Hide the Full List
mod site	chr2:189004082-189004083:+		[6]
Sequence	GGCAGCCCTGGAGTGTCTGGACCAAAAGGTGATGCTGGCCA
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503324
mod ID: M6ASITE048976		Click to Show/Hide the Full List
mod site	chr2:189004312-189004313:+		[6]
Sequence	GGAGCACGGGGTCTTGCAGGACCACCAGGCATGCCAGGTCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503325
mod ID: M6ASITE048977		Click to Show/Hide the Full List
mod site	chr2:189005363-189005364:+		[6]
Sequence	ATACAGGGTGAAAGTGGGAAACCAGGAGCTAACGGTCTCAG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503326
mod ID: M6ASITE048978		Click to Show/Hide the Full List
mod site	chr2:189005405-189005406:+		[6]
Sequence	GGAGAACGTGGTCCCCCTGGACCCCAGGGTCTTCCTGGTCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503327
mod ID: M6ASITE048979		Click to Show/Hide the Full List
mod site	chr2:189005433-189005434:+		[4]
Sequence	GTCTTCCTGGTCTGGCTGGTACAGCTGGTGAACCTGGAAGA
Motif Score	2.856142857
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503328
mod ID: M6ASITE048980		Click to Show/Hide the Full List
mod site	chr2:189005444-189005445:+		[5]
Sequence	CTGGCTGGTACAGCTGGTGAACCTGGAAGAGATGTGAGTAG
Motif Score	2.930744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503329
mod ID: M6ASITE048981		Click to Show/Hide the Full List
mod site	chr2:189006209-189006210:+		[5]
Sequence	CTCATTTTTTAATCAGGGAAACCCTGGATCAGATGGTCTTC
Motif Score	2.185083333
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503330
mod ID: M6ASITE048982		Click to Show/Hide the Full List
mod site	chr2:189007532-189007533:+		[5]
Sequence	CACGTGGTGACAAAGGTGAAACAGGTGAACGTGGAGCTGCT
Motif Score	2.20572619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503331
mod ID: M6ASITE048983		Click to Show/Hide the Full List
mod site	chr2:189007564-189007565:+		[5]
Sequence	GGAGCTGCTGGCATCAAAGGACATCGAGGATTCCCTGGTAA
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503332
mod ID: M6ASITE048984		Click to Show/Hide the Full List
mod site	chr2:189007922-189007923:+		[5]
Sequence	GGTGCAATCGGCAGTCCAGGACCTGCAGGCCCCAGAGTAAG
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503333
mod ID: M6ASITE048985		Click to Show/Hide the Full List
mod site	chr2:189008036-189008037:+		[6]
Sequence	GTCATGATACTTTCTTAGGGACCTGTTGGACCCAGTGGACC
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503334
mod ID: M6ASITE048986		Click to Show/Hide the Full List
mod site	chr2:189008045-189008046:+		[6]
Sequence	CTTTCTTAGGGACCTGTTGGACCCAGTGGACCTCCTGGCAA
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503335
mod ID: M6ASITE048987		Click to Show/Hide the Full List
mod site	chr2:189008054-189008055:+		[6]
Sequence	GGACCTGTTGGACCCAGTGGACCTCCTGGCAAAGATGGAAC
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7
External Link	RMBase: m6A_site_503336
mod ID: M6ASITE048988		Click to Show/Hide the Full List
mod site	chr2:189008073-189008074:+		[6]
Sequence	GACCTCCTGGCAAAGATGGAACCAGTGGACATCCAGGTCCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503337
mod ID: M6ASITE048989		Click to Show/Hide the Full List
mod site	chr2:189008081-189008082:+		[6]
Sequence	GGCAAAGATGGAACCAGTGGACATCCAGGTCCCATTGGACC
Motif Score	3.643047619
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503338
mod ID: M6ASITE048990		Click to Show/Hide the Full List
mod site	chr2:189008099-189008100:+		[6]
Sequence	GGACATCCAGGTCCCATTGGACCACCAGGGCCTCGAGGTAA
Motif Score	3.622404762
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503339
mod ID: M6ASITE048991		Click to Show/Hide the Full List
mod site	chr2:189008402-189008403:+		[5]
Sequence	CTGCCCAATTAACCAAATAAACCCTGTCCACATTGCTATCC
Motif Score	2.185083333
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000487010.1
External Link	RMBase: m6A_site_503340
mod ID: M6ASITE048992		Click to Show/Hide the Full List
mod site	chr2:189008961-189008962:+		[5]
Sequence	GGGCAACCAGGCCCTCCTGGACCTCCTGGTGCCCCTGGTCC
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000487010.1
External Link	RMBase: m6A_site_503341
mod ID: M6ASITE048993		Click to Show/Hide the Full List
mod site	chr2:189009066-189009067:+		[5]
Sequence	GCCCCGTATTATGGAGATGAACCAATGGATTTCAAAATCAA
Motif Score	2.930744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: m6A_site_503342
mod ID: M6ASITE048994		Click to Show/Hide the Full List
mod site	chr2:189009126-189009127:+		[5]
Sequence	TCACTCAAGTCTGTTAATGGACAAATAGAAAGCCTCATTAG
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000487010.1; ENST00000317840.9
External Link	RMBase: m6A_site_503343
mod ID: M6ASITE048995		Click to Show/Hide the Full List
mod site	chr2:189009167-189009168:+		[5]
Sequence	TCCTGATGGTTCTCGTAAAAACCCCGCTAGAAACTGCAGAG
Motif Score	2.185083333
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9; ENST00000487010.1
External Link	RMBase: m6A_site_503344
mod ID: M6ASITE048996		Click to Show/Hide the Full List
mod site	chr2:189009179-189009180:+		[5]
Sequence	TCGTAAAAACCCCGCTAGAAACTGCAGAGACCTGAAATTCT
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: m6A_site_503345
mod ID: M6ASITE048997		Click to Show/Hide the Full List
mod site	chr2:189009188-189009189:+		[5]
Sequence	CCCCGCTAGAAACTGCAGAGACCTGAAATTCTGCCATCCTG
Motif Score	2.876744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000487010.1; ENST00000317840.9
External Link	RMBase: m6A_site_503346
mod ID: M6ASITE048998		Click to Show/Hide the Full List
mod site	chr2:189009210-189009211:+		[5]
Sequence	CTGAAATTCTGCCATCCTGAACTCAAGAGTGGTATGTTTGG
Motif Score	3.373380952
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000487010.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503347
mod ID: M6ASITE048999		Click to Show/Hide the Full List
mod site	chr2:189010245-189010246:+		[5]
Sequence	AGGTATTCTGTAATATGGAAACTGGGGAAACATGCATAAGT
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: m6A_site_503348
mod ID: M6ASITE049000		Click to Show/Hide the Full List
mod site	chr2:189010254-189010255:+		[5]
Sequence	GTAATATGGAAACTGGGGAAACATGCATAAGTGCCAATCCT
Motif Score	2.20572619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000487010.1
External Link	RMBase: m6A_site_503349
mod ID: M6ASITE049001		Click to Show/Hide the Full List
mod site	chr2:189010292-189010293:+		[5]
Sequence	CCTTTGAATGTTCCACGGAAACACTGGTGGACAGATTCTAG
Motif Score	2.20572619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000487010.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503350
mod ID: M6ASITE049002		Click to Show/Hide the Full List
mod site	chr2:189010302-189010303:+		[5]
Sequence	TTCCACGGAAACACTGGTGGACAGATTCTAGTGCTGAGAAG
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9; ENST00000487010.1
External Link	RMBase: m6A_site_503351
mod ID: M6ASITE049003		Click to Show/Hide the Full List
mod site	chr2:189010325-189010326:+		[5]
Sequence	GATTCTAGTGCTGAGAAGAAACACGTTTGGTTTGGAGAGTC
Motif Score	2.20572619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000487010.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503352
mod ID: M6ASITE049004		Click to Show/Hide the Full List
mod site	chr2:189010667-189010668:+		[5]
Sequence	TTTAGCTACGGCAATCCTGAACTTCCTGAAGATGTCCTTGA
Motif Score	3.373380952
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000487010.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503353
mod ID: M6ASITE049005		Click to Show/Hide the Full List
mod site	chr2:189010735-189010736:+		[5]
Sequence	CTCCAGCCGAGCTTCCCAGAACATCACATATCACTGCAAAA
Motif Score	2.951386905
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: m6A_site_503354
mod ID: M6ASITE049006		Click to Show/Hide the Full List
mod site	chr2:189011629-189011630:+		[5]
Sequence	TTTTGTCCTTTTTTACAGAAACACACTGGGGAATGGAGCAA
Motif Score	2.20572619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: m6A_site_503355
mod ID: M6ASITE049007		Click to Show/Hide the Full List
mod site	chr2:189011651-189011652:+		[4]
Sequence	ACACTGGGGAATGGAGCAAAACAGTCTTTGAATATCGAACA
Motif Score	2.20572619
Cell/Tissue List	liver; endometrial
Seq Type List	m6A-REF-seq; m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9; ENST00000487010.1
External Link	RMBase: m6A_site_503356
mod ID: M6ASITE049008		Click to Show/Hide the Full List
mod site	chr2:189011669-189011670:+		[5]
Sequence	AAACAGTCTTTGAATATCGAACACGCAAGGCTGTGAGACTA
Motif Score	2.951386905
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: m6A_site_503357
mod ID: M6ASITE049009		Click to Show/Hide the Full List
mod site	chr2:189011686-189011687:+		[5]
Sequence	CGAACACGCAAGGCTGTGAGACTACCTATTGTAGATATTGC
Motif Score	3.319380952
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000304636.7; ENST00000317840.9; ENST00000487010.1
External Link	RMBase: m6A_site_503358
mod ID: M6ASITE049010		Click to Show/Hide the Full List
mod site	chr2:189011774-189011775:+		[5]
Sequence	GCCCTGTTTGCTTTTTATAAACCAAACTCTATCTGAAATCC
Motif Score	2.185083333
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000487010.1; ENST00000304636.7; ENST00000317840.9
External Link	RMBase: m6A_site_503359
mod ID: M6ASITE049011		Click to Show/Hide the Full List
mod site	chr2:189011779-189011780:+		[5]
Sequence	GTTTGCTTTTTATAAACCAAACTCTATCTGAAATCCCAACA
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000317840.9; ENST00000304636.7; ENST00000487010.1
External Link	RMBase: m6A_site_503360

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000147		Click to Show/Hide the Full List
mod site	chr2:189010127-189010128:+		[7]
Sequence	GGTAAACAAACAAAATCACTTTATTACTGGATTTTATAACC
Transcript ID List	ENST00000317840.9; ENST00000487010.1; ENST00000304636.7
External Link	RMBase: Pseudo_site_2770

Ref 1	Reduced Expression of METTL3 Promotes Metastasis of Triple-Negative Breast Cancer by m6A Methylation-Mediated COL3A1 Up-Regulation. Front Oncol. 2020 Jul 14;10:1126. doi: 10.3389/fonc.2020.01126. eCollection 2020.
Ref 2	[Non-surgical treatment of osteoarthritis of large joints - new aspects]. Wien Med Wochenschr. 2009;159(3-4):76-86. doi: 10.1007/s10354-008-0603-2.
Ref 3	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 4	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 5	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 6	RNA m(6)A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. Nat Commun. 2019 May 6;10(1):2065. doi: 10.1038/s41467-019-09865-9.
Ref 7	Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells. Nature. 2014 Nov 6;515(7525):143-6. doi: 10.1038/nature13802. Epub 2014 Sep 5.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map