m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00476)
Target Name High mobility group protein HMG-I/HMG-Y (HMGA1)
Synonyms
HMG-I(Y); High mobility group AT-hook protein 1; High mobility group protein A1; High mobility group protein R; HMGIY
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Gene Name HMGA1
Chromosomal Location 6p21.31
Family HMGA family. {ECO:0000305}.
Function
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
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Gene ID 26574
Uniprot ID
HMGA1_HUMAN
HGNC ID
HGNC:5010
KEGG ID
hsa:3159
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
HMGA1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Regulator
Browse Disease
Methyltransferase-like 3 (METTL3) [WRITER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by METTL3
Cell Line Caco-2 cell line Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
 GSE167075
Regulation
logFC: -8.70E-01
p-value: 2.47E-77
More Results Click to View More RNA-seq Results
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary LINC00460 is a novel oncogene of colorectal cancer through interacting with IGF2BP2 and DHX9 and bind to the m6A modified High mobility group protein HMG-I/HMG-Y (HMGA1) mRNA to enhance the HMGA1 mRNA stability. The N6-methyladenosine (m6A) modification of HMGA1 mRNA by METTL3 enhanced HMGA1 expression in CRC.
Target Regulation Up regulation
Responsed Disease Colorectal cancer ICD-11: 2B91
 Disease Info 
Pathway Response mRNA surveillance pathway hsa03015
Cell Process mRNA stability
Epithelial-mesenchymal transition
In-vitro Model DLD-1 Colon adenocarcinoma Homo sapiens CVCL_0248
FHC Normal Homo sapiens CVCL_3688
HCT 116 Colon carcinoma Homo sapiens CVCL_0291
HEK293T Normal Homo sapiens CVCL_0063
HT29 Colon cancer Mus musculus CVCL_A8EZ
LoVo Colon adenocarcinoma Homo sapiens CVCL_0399
SW480 Colon adenocarcinoma Homo sapiens CVCL_0546
SW620 Colon adenocarcinoma Homo sapiens CVCL_0547
In-vivo Model Groups of HCT116-Luc-shCtrl, HCT116-Luc-shLINC00460, and HCT116-Luc-shLINC00460 + HMGA1 cells (5 × 106) were injected subcutaneously into the flanks of mice correspondingly.
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) [READER]
 Regulator Info 
Representative RIP-seq result supporting the interaction between HMGA1 and the regulator
Cell Line HEK293T Homo sapiens
Regulation logFC: 1.10E+00 GSE90639
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary LINC00460 is a novel oncogene of colorectal cancer through interacting with IGF2BP2 and DHX9 and bind to the m6A modified High mobility group protein HMG-I/HMG-Y (HMGA1) mRNA to enhance the HMGA1 mRNA stability. The N6-methyladenosine (m6A) modification of HMGA1 mRNA by METTL3 enhanced HMGA1 expression in CRC.
Target Regulation Up regulation
Responsed Disease Colorectal cancer ICD-11: 2B91
 Disease Info 
Pathway Response mRNA surveillance pathway hsa03015
Cell Process mRNA stability
Epithelial-mesenchymal transition
In-vitro Model DLD-1 Colon adenocarcinoma Homo sapiens CVCL_0248
FHC Normal Homo sapiens CVCL_3688
HCT 116 Colon carcinoma Homo sapiens CVCL_0291
HEK293T Normal Homo sapiens CVCL_0063
HT29 Colon cancer Mus musculus CVCL_A8EZ
LoVo Colon adenocarcinoma Homo sapiens CVCL_0399
SW480 Colon adenocarcinoma Homo sapiens CVCL_0546
SW620 Colon adenocarcinoma Homo sapiens CVCL_0547
In-vivo Model Groups of HCT116-Luc-shCtrl, HCT116-Luc-shLINC00460, and HCT116-Luc-shLINC00460 + HMGA1 cells (5 × 106) were injected subcutaneously into the flanks of mice correspondingly.
Colorectal cancer [ICD-11: 2B91]
 Disease Info 
In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary LINC00460 is a novel oncogene of colorectal cancer through interacting with IGF2BP2 and DHX9 and bind to the m6A modified High mobility group protein HMG-I/HMG-Y (HMGA1) mRNA to enhance the HMGA1 mRNA stability. The N6-methyladenosine (m6A) modification of HMGA1 mRNA by METTL3 enhanced HMGA1 expression in CRC.
Responsed Disease Colorectal cancer [ICD-11: 2B91]
Target Regulator Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) READER
 Regulator Info 
Target Regulation Up regulation
Pathway Response mRNA surveillance pathway hsa03015
Cell Process mRNA stability
Epithelial-mesenchymal transition
In-vitro Model DLD-1 Colon adenocarcinoma Homo sapiens CVCL_0248
FHC Normal Homo sapiens CVCL_3688
HCT 116 Colon carcinoma Homo sapiens CVCL_0291
HEK293T Normal Homo sapiens CVCL_0063
HT29 Colon cancer Mus musculus CVCL_A8EZ
LoVo Colon adenocarcinoma Homo sapiens CVCL_0399
SW480 Colon adenocarcinoma Homo sapiens CVCL_0546
SW620 Colon adenocarcinoma Homo sapiens CVCL_0547
In-vivo Model Groups of HCT116-Luc-shCtrl, HCT116-Luc-shLINC00460, and HCT116-Luc-shLINC00460 + HMGA1 cells (5 × 106) were injected subcutaneously into the flanks of mice correspondingly.
Experiment 2 Reporting the m6A-centered Disease Response [1]
Response Summary LINC00460 is a novel oncogene of colorectal cancer through interacting with IGF2BP2 and DHX9 and bind to the m6A modified High mobility group protein HMG-I/HMG-Y (HMGA1) mRNA to enhance the HMGA1 mRNA stability. The N6-methyladenosine (m6A) modification of HMGA1 mRNA by METTL3 enhanced HMGA1 expression in CRC.
Responsed Disease Colorectal cancer [ICD-11: 2B91]
Target Regulator Methyltransferase-like 3 (METTL3) WRITER
 Regulator Info 
Target Regulation Up regulation
Pathway Response mRNA surveillance pathway hsa03015
Cell Process mRNA stability
Epithelial-mesenchymal transition
In-vitro Model DLD-1 Colon adenocarcinoma Homo sapiens CVCL_0248
FHC Normal Homo sapiens CVCL_3688
HCT 116 Colon carcinoma Homo sapiens CVCL_0291
HEK293T Normal Homo sapiens CVCL_0063
HT29 Colon cancer Mus musculus CVCL_A8EZ
LoVo Colon adenocarcinoma Homo sapiens CVCL_0399
SW480 Colon adenocarcinoma Homo sapiens CVCL_0546
SW620 Colon adenocarcinoma Homo sapiens CVCL_0547
In-vivo Model Groups of HCT116-Luc-shCtrl, HCT116-Luc-shLINC00460, and HCT116-Luc-shLINC00460 + HMGA1 cells (5 × 106) were injected subcutaneously into the flanks of mice correspondingly.
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Histone modification
m6A Regulator: Methyltransferase-like 3 (METTL3)
 Regulator Info 
In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03552
 Crosstalk Info 
Epigenetic Regulator Histone acetyltransferase p300 (P300)
Regulated Target Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
 Disease Info 
Crosstalk ID: M6ACROT03597
 Crosstalk Info 
Epigenetic Regulator N-lysine methyltransferase SMYD2 (SMYD2)
Regulated Target Histone H3 lysine 4 trimethylation (H3K4me3)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
 Disease Info 
Non-coding RNA
m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
 Regulator Info 
In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05274
 Crosstalk Info 
Epigenetic Regulator Long intergenic non-protein coding RNA 460 (LINC00460)
Regulated Target Insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2)
Crosstalk relationship ncRNA → m6A
Disease Colorectal cancer
 Disease Info 
Crosstalk ID: M6ACROT05372
 Crosstalk Info 
Epigenetic Regulator Long intergenic non-protein coding RNA 460 (LINC00460)
Regulated Target Insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2)
Crosstalk relationship ncRNA → m6A
Disease Colorectal cancer
 Disease Info 
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00476)
High mobility group protein HMG-I/HMG-Y (HMGA1)
N4-acetylcytidine (ac4C)
In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000104 Click to Show/Hide the Full List
mod site chr6:34244855-34244856:+ [3]
Sequence GGAGGAAGAGGAGGGCATCTCGCAGGAGTCCTCGGAGGAGG
Cell/Tissue List H1
Seq Type List ac4C-seq
Transcript ID List ENST00000401473.7; ENST00000347617.10; ENST00000374116.3; ENST00000478214.1; ENST00000311487.9; ENST00000447654.5
External Link RMBase: ac4C_site_1586
N1-methyladenosine (m1A)
In total 1 m6A sequence/site(s) in this target gene
mod ID: M1ASITE000107 Click to Show/Hide the Full List
mod site chr6:34246021-34246022:+ [4]
Sequence CATGGCAGGCTGGGTGACCGACTACCCCAGTCCCAGGGAAG
Cell/Tissue List HEK293T
Seq Type List m1A-seq
Transcript ID List ENST00000374116.3; ENST00000347617.10; ENST00000311487.9; ENST00000401473.7; ENST00000447654.5
External Link RMBase: m1A_site_911
5-methylcytidine (m5C)
In total 28 m6A sequence/site(s) in this target gene
mod ID: M5CSITE003890 Click to Show/Hide the Full List
mod site chr6:34236919-34236920:+ [5]
Sequence GCGCTCCTCTAATTGGGACTCCGAGCCGGGGCTATTTCTGG
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000311487.9; ENST00000447654.5
External Link RMBase: m5C_site_37804
mod ID: M5CSITE003891 Click to Show/Hide the Full List
mod site chr6:34236920-34236921:+ [5]
Sequence CGCTCCTCTAATTGGGACTCCGAGCCGGGGCTATTTCTGGC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000311487.9; ENST00000347617.10; ENST00000401473.7
External Link RMBase: m5C_site_37805
mod ID: M5CSITE003892 Click to Show/Hide the Full List
mod site chr6:34236924-34236925:+ [5]
Sequence CCTCTAATTGGGACTCCGAGCCGGGGCTATTTCTGGCGCTG
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000347617.10; ENST00000311487.9; ENST00000401473.7
External Link RMBase: m5C_site_37806
mod ID: M5CSITE003893 Click to Show/Hide the Full List
mod site chr6:34237228-34237229:+
Sequence CATTTGCTACCAGCGGCGGCCGCGGCGGAGCCAGGCCGGTC
Cell/Tissue List muscle
Seq Type List Bisulfite-seq
Transcript ID List ENST00000401473.7; ENST00000478214.1; ENST00000311487.9; ENST00000447654.5; ENST00000347617.10
External Link RMBase: m5C_site_37807
mod ID: M5CSITE003894 Click to Show/Hide the Full List
mod site chr6:34237534-34237535:+
Sequence GAGGACGCCCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTG
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000478214.1; ENST00000447654.5; ENST00000347617.10; ENST00000401473.7; ENST00000311487.9
External Link RMBase: m5C_site_37808
mod ID: M5CSITE003895 Click to Show/Hide the Full List
mod site chr6:34237535-34237536:+
Sequence AGGACGCCCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTGC
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000478214.1; ENST00000347617.10; ENST00000311487.9; ENST00000401473.7
External Link RMBase: m5C_site_37809
mod ID: M5CSITE003897 Click to Show/Hide the Full List
mod site chr6:34237536-34237537:+
Sequence GGACGCCCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTGCG
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000401473.7; ENST00000478214.1; ENST00000447654.5; ENST00000311487.9; ENST00000347617.10
External Link RMBase: m5C_site_37810
mod ID: M5CSITE003898 Click to Show/Hide the Full List
mod site chr6:34237537-34237538:+
Sequence GACGCCCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTGCGG
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000311487.9; ENST00000478214.1; ENST00000401473.7; ENST00000347617.10; ENST00000447654.5
External Link RMBase: m5C_site_37811
mod ID: M5CSITE003899 Click to Show/Hide the Full List
mod site chr6:34237539-34237540:+
Sequence CGCCCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTGCGGGG
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000311487.9; ENST00000478214.1; ENST00000347617.10; ENST00000401473.7
External Link RMBase: m5C_site_37812
mod ID: M5CSITE003900 Click to Show/Hide the Full List
mod site chr6:34237541-34237542:+
Sequence CCCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTGCGGGGGG
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000311487.9; ENST00000478214.1; ENST00000447654.5; ENST00000401473.7
External Link RMBase: m5C_site_37813
mod ID: M5CSITE003901 Click to Show/Hide the Full List
mod site chr6:34237542-34237543:+
Sequence CCGCACCCCTTCCCCCGCGCCGCGGGCGCCCTGCGGGGGGC
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000447654.5; ENST00000478214.1; ENST00000311487.9; ENST00000401473.7
External Link RMBase: m5C_site_37814
mod ID: M5CSITE003902 Click to Show/Hide the Full List
mod site chr6:34237544-34237545:+
Sequence GCACCCCTTCCCCCGCGCCGCGGGCGCCCTGCGGGGGGCGG
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000401473.7; ENST00000347617.10; ENST00000311487.9; ENST00000478214.1
External Link RMBase: m5C_site_37815
mod ID: M5CSITE003903 Click to Show/Hide the Full List
mod site chr6:34240725-34240726:+ [5]
Sequence GTTTGTCTAAAAGCACTTTTCTGTCTCCCAGCATCCCAGCC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000374116.3; ENST00000401473.7; ENST00000621552.1; ENST00000478214.1; ENST00000447654.5; ENST00000311487.9; MIMAT0027571; ENST00000347617.10
External Link RMBase: m5C_site_37816
mod ID: M5CSITE003904 Click to Show/Hide the Full List
mod site chr6:34241418-34241419:+
Sequence TCCCAGGTGAGAAACGGGTGCCTGCGTGGGCCAGCACCTGT
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000401473.7; ENST00000311487.9; ENST00000447654.5; ENST00000478214.1; ENST00000347617.10; ENST00000374116.3
External Link RMBase: m5C_site_37817
mod ID: M5CSITE003905 Click to Show/Hide the Full List
mod site chr6:34244927-34244928:+ [5]
Sequence ACTGGAGGAGCAGCTTCCTTCTGGGACTGGACAGCTTTGCT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000401473.7; ENST00000347617.10; ENST00000447654.5; ENST00000311487.9; ENST00000478214.1; ENST00000374116.3
External Link RMBase: m5C_site_37818
mod ID: M5CSITE003906 Click to Show/Hide the Full List
mod site chr6:34245099-34245100:+ [5]
Sequence TGAGTGGGGAGCAGTTTTCCCCTGGCCTCAGTTCCCAGCTC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000311487.9; ENST00000347617.10; ENST00000401473.7; ENST00000374116.3; ENST00000478214.1
External Link RMBase: m5C_site_37819
mod ID: M5CSITE003908 Click to Show/Hide the Full List
mod site chr6:34245255-34245256:+ [5]
Sequence GGGCTTTTGGTTTGGGGGCGCCCTCTCTGCTCCTTCACTGT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000311487.9; ENST00000374116.3; ENST00000347617.10; ENST00000401473.7
External Link RMBase: m5C_site_37820
mod ID: M5CSITE003909 Click to Show/Hide the Full List
mod site chr6:34245256-34245257:+ [5]
Sequence GGCTTTTGGTTTGGGGGCGCCCTCTCTGCTCCTTCACTGTT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000374116.3; ENST00000311487.9; ENST00000401473.7; ENST00000347617.10; ENST00000447654.5
External Link RMBase: m5C_site_37821
mod ID: M5CSITE003910 Click to Show/Hide the Full List
mod site chr6:34245257-34245258:+ [5]
Sequence GCTTTTGGTTTGGGGGCGCCCTCTCTGCTCCTTCACTGTTC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000311487.9; ENST00000374116.3; ENST00000447654.5
External Link RMBase: m5C_site_37822
mod ID: M5CSITE003911 Click to Show/Hide the Full List
mod site chr6:34245259-34245260:+ [5]
Sequence TTTTGGTTTGGGGGCGCCCTCTCTGCTCCTTCACTGTTCCC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000311487.9; ENST00000447654.5; ENST00000374116.3; ENST00000401473.7
External Link RMBase: m5C_site_37823
mod ID: M5CSITE003912 Click to Show/Hide the Full List
mod site chr6:34245261-34245262:+ [5]
Sequence TTGGTTTGGGGGCGCCCTCTCTGCTCCTTCACTGTTCCCTC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000447654.5; ENST00000311487.9; ENST00000374116.3
External Link RMBase: m5C_site_37824
mod ID: M5CSITE003913 Click to Show/Hide the Full List
mod site chr6:34245412-34245413:+ [6]
Sequence CAATGGAGGGGGGTGCTGGCCCCCAGGATTCCCCCAGCCAA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000347617.10; ENST00000374116.3; ENST00000401473.7; ENST00000311487.9
External Link RMBase: m5C_site_37825
mod ID: M5CSITE003914 Click to Show/Hide the Full List
mod site chr6:34245413-34245414:+ [6]
Sequence AATGGAGGGGGGTGCTGGCCCCCAGGATTCCCCCAGCCAAA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000374116.3; ENST00000401473.7; ENST00000347617.10; ENST00000311487.9
External Link RMBase: m5C_site_37826
mod ID: M5CSITE003915 Click to Show/Hide the Full List
mod site chr6:34245414-34245415:+ [6]
Sequence ATGGAGGGGGGTGCTGGCCCCCAGGATTCCCCCAGCCAAAC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000447654.5; ENST00000347617.10; ENST00000401473.7; ENST00000374116.3; ENST00000311487.9
External Link RMBase: m5C_site_37827
mod ID: M5CSITE003916 Click to Show/Hide the Full List
mod site chr6:34245415-34245416:+ [6]
Sequence TGGAGGGGGGTGCTGGCCCCCAGGATTCCCCCAGCCAAACT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000311487.9; ENST00000374116.3; ENST00000347617.10; ENST00000401473.7; ENST00000447654.5
External Link RMBase: m5C_site_37828
mod ID: M5CSITE003917 Click to Show/Hide the Full List
mod site chr6:34245458-34245459:+ [5]
Sequence CTTTGTCACCACGTGGGGCTCACTTTTCATCCTTCCCCAAC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000401473.7; ENST00000374116.3; ENST00000447654.5; ENST00000311487.9; ENST00000347617.10
External Link RMBase: m5C_site_37829
mod ID: M5CSITE003919 Click to Show/Hide the Full List
mod site chr6:34245732-34245733:+ [5]
Sequence CGCCACTCAGCCATTTCCCCCTCCTCAGATGGGGCACCAAT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000401473.7; ENST00000347617.10; ENST00000447654.5; ENST00000311487.9; ENST00000374116.3
External Link RMBase: m5C_site_37830
mod ID: M5CSITE003920 Click to Show/Hide the Full List
mod site chr6:34245961-34245962:+ [5]
Sequence TCCTGTTCTGCCCACGATCCCCTCCCCCAAGATACTCTTTG
Seq Type List Bisulfite-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000311487.9; ENST00000374116.3; ENST00000447654.5
External Link RMBase: m5C_site_37831
N6-methyladenosine (m6A)
In total 35 m6A sequence/site(s) in this target gene
mod ID: M6ASITE074653 Click to Show/Hide the Full List
mod site chr6:34236916-34236917:+ [7]
Sequence GCTGCGCTCCTCTAATTGGGACTCCGAGCCGGGGCTATTTC
Motif Score 4.065041667
Cell/Tissue List HepG2
Seq Type List m6A-seq
Transcript ID List ENST00000447654.5; ENST00000347617.10; ENST00000401473.7; ENST00000311487.9
External Link RMBase: m6A_site_713498
mod ID: M6ASITE074654 Click to Show/Hide the Full List
mod site chr6:34238848-34238849:+ [8]
Sequence GTATGAGAGCTTCCAGGGAGACCCGCCAAGATCTCCAGGCA
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; U2OS; MT4; GSC-11; HEK293T; MM6
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000347617.10; ENST00000374116.3; ENST00000311487.9; ENST00000478214.1; ENST00000401473.7; ENST00000447654.5
External Link RMBase: m6A_site_713499
mod ID: M6ASITE074656 Click to Show/Hide the Full List
mod site chr6:34238897-34238898:+ [8]
Sequence CAGGCTCTCTGGGATTCCGGACTGGCTTCGCCCAACTGGAA
Motif Score 4.065041667
Cell/Tissue List HeLa; MT4; HEK293T
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000374116.3; ENST00000447654.5; ENST00000478214.1; ENST00000311487.9; ENST00000347617.10; ENST00000401473.7
External Link RMBase: m6A_site_713500
mod ID: M6ASITE074657 Click to Show/Hide the Full List
mod site chr6:34238917-34238918:+ [8]
Sequence ACTGGCTTCGCCCAACTGGAACCCCCTCGATGAGGGGGCCC
Motif Score 2.930744048
Cell/Tissue List HeLa; MT4; HEK293T
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000311487.9; ENST00000447654.5; ENST00000478214.1; ENST00000374116.3
External Link RMBase: m6A_site_713501
mod ID: M6ASITE074658 Click to Show/Hide the Full List
mod site chr6:34238945-34238946:+ [8]
Sequence GATGAGGGGGCCCCAGGCAGACCTTATATGAGGTCAGCACT
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; U2OS; MT4; MM6; Huh7; peripheral-blood; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000447654.5; ENST00000347617.10; ENST00000401473.7; ENST00000478214.1; ENST00000374116.3; ENST00000311487.9
External Link RMBase: m6A_site_713502
mod ID: M6ASITE074659 Click to Show/Hide the Full List
mod site chr6:34240894-34240895:+ [8]
Sequence AGCCTCCGGTGAGTCCCGGGACAGCGCTGGTAGGGAGTCAG
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2; U2OS; H1A; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000311487.9; ENST00000401473.7; ENST00000374116.3; ENST00000447654.5; ENST00000347617.10; ENST00000478214.1
External Link RMBase: m6A_site_713503
mod ID: M6ASITE074660 Click to Show/Hide the Full List
mod site chr6:34242732-34242733:+ [9]
Sequence AGGAGCCCAGCGAAGTGCCAACACCTAAGAGACCTCGGGGC
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000401473.7; ENST00000447654.5; ENST00000311487.9; ENST00000347617.10; ENST00000478214.1; ENST00000374116.3
External Link RMBase: m6A_site_713504
mod ID: M6ASITE074661 Click to Show/Hide the Full List
mod site chr6:34242743-34242744:+ [8]
Sequence GAAGTGCCAACACCTAAGAGACCTCGGGGCCGACCAAAGGG
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; U2OS; H1A; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000347617.10; ENST00000478214.1; ENST00000401473.7; ENST00000311487.9; ENST00000447654.5; ENST00000374116.3
External Link RMBase: m6A_site_713505
mod ID: M6ASITE074662 Click to Show/Hide the Full List
mod site chr6:34242772-34242773:+ [8]
Sequence CCGACCAAAGGGAAGCAAAAACAAGGGTGCTGCCAAGACCC
Motif Score 2.20572619
Cell/Tissue List HeLa; HepG2; hESC-HEK293T; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List ENST00000447654.5; ENST00000401473.7; ENST00000478214.1; ENST00000374116.3; ENST00000311487.9; ENST00000347617.10
External Link RMBase: m6A_site_713506
mod ID: M6ASITE074663 Click to Show/Hide the Full List
mod site chr6:34242789-34242790:+ [8]
Sequence AAAACAAGGGTGCTGCCAAGACCCGGGTGAGACTTGAGATG
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000447654.5; ENST00000478214.1; ENST00000311487.9; ENST00000401473.7; ENST00000374116.3; ENST00000347617.10
External Link RMBase: m6A_site_713507
mod ID: M6ASITE074664 Click to Show/Hide the Full List
mod site chr6:34243470-34243471:+ [8]
Sequence TTTCTCTAACCCTCTAGAAAACCACCACAACTCCAGGAAGG
Motif Score 2.185083333
Cell/Tissue List HeLa; HepG2; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000447654.5; ENST00000374116.3; ENST00000311487.9; ENST00000478214.1; ENST00000401473.7; ENST00000347617.10
External Link RMBase: m6A_site_713508
mod ID: M6ASITE074665 Click to Show/Hide the Full List
mod site chr6:34243476-34243477:+ [9]
Sequence TAACCCTCTAGAAAACCACCACAACTCCAGGAAGGAAACCA
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000374116.3; ENST00000347617.10; ENST00000311487.9; ENST00000401473.7; ENST00000447654.5; ENST00000478214.1
External Link RMBase: m6A_site_713509
mod ID: M6ASITE074666 Click to Show/Hide the Full List
mod site chr6:34243493-34243494:+ [8]
Sequence ACCACAACTCCAGGAAGGAAACCAAGGGGCAGACCCAAAAA
Motif Score 2.185083333
Cell/Tissue List HeLa; HepG2; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000374116.3; ENST00000478214.1; ENST00000401473.7; ENST00000347617.10; ENST00000311487.9; ENST00000447654.5
External Link RMBase: m6A_site_713510
mod ID: M6ASITE074667 Click to Show/Hide the Full List
mod site chr6:34243505-34243506:+ [8]
Sequence GGAAGGAAACCAAGGGGCAGACCCAAAAAACTGGTAGGTGA
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000374116.3; ENST00000478214.1; ENST00000311487.9; ENST00000447654.5
External Link RMBase: m6A_site_713511
mod ID: M6ASITE074668 Click to Show/Hide the Full List
mod site chr6:34243514-34243515:+ [8]
Sequence CCAAGGGGCAGACCCAAAAAACTGGTAGGTGAAGAAGCAGA
Motif Score 2.627720238
Cell/Tissue List HeLa; HepG2; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000478214.1; ENST00000374116.3; ENST00000447654.5; ENST00000347617.10; ENST00000311487.9; ENST00000401473.7
External Link RMBase: m6A_site_713512
mod ID: M6ASITE074669 Click to Show/Hide the Full List
mod site chr6:34244932-34244933:+ [8]
Sequence AGGAGCAGCTTCCTTCTGGGACTGGACAGCTTTGCTCCGCT
Motif Score 4.065041667
Cell/Tissue List HeLa; HepG2; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000347617.10; ENST00000311487.9; ENST00000374116.3; ENST00000447654.5; ENST00000401473.7; ENST00000478214.1
External Link RMBase: m6A_site_713513
mod ID: M6ASITE074670 Click to Show/Hide the Full List
mod site chr6:34244937-34244938:+ [8]
Sequence CAGCTTCCTTCTGGGACTGGACAGCTTTGCTCCGCTCCCAC
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2; HEK293T; U2OS; H1A; LCLs; MT4; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; DART-seq; MeRIP-seq
Transcript ID List ENST00000347617.10; ENST00000311487.9; ENST00000447654.5; ENST00000374116.3; ENST00000401473.7; ENST00000478214.1
External Link RMBase: m6A_site_713514
mod ID: M6ASITE074671 Click to Show/Hide the Full List
mod site chr6:34245038-34245039:+ [9]
Sequence CCACCTGTGCCCTCACCACCACACTACACAGCACACCAGCC
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000401473.7; ENST00000347617.10; ENST00000311487.9; ENST00000374116.3; ENST00000447654.5; ENST00000478214.1
External Link RMBase: m6A_site_713515
mod ID: M6ASITE074672 Click to Show/Hide the Full List
mod site chr6:34245050-34245051:+ [9]
Sequence TCACCACCACACTACACAGCACACCAGCCGCTGCAGGGCTC
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000447654.5; ENST00000478214.1; ENST00000374116.3; ENST00000347617.10; ENST00000311487.9; ENST00000401473.7
External Link RMBase: m6A_site_713516
mod ID: M6ASITE074673 Click to Show/Hide the Full List
mod site chr6:34245139-34245140:+ [10]
Sequence CCCCCCGCCCACCCACGCATACACACATGCCCTCCTGGACA
Motif Score 2.110482143
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000374116.3; ENST00000311487.9; ENST00000347617.10; ENST00000447654.5; ENST00000401473.7; ENST00000478214.1
External Link RMBase: m6A_site_713517
mod ID: M6ASITE074674 Click to Show/Hide the Full List
mod site chr6:34245157-34245158:+ [8]
Sequence ATACACACATGCCCTCCTGGACAAGGCTAACATCCCACTTA
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2
Seq Type List m6A-seq
Transcript ID List ENST00000374116.3; ENST00000447654.5; ENST00000311487.9; ENST00000347617.10; ENST00000401473.7
External Link RMBase: m6A_site_713518
mod ID: M6ASITE074675 Click to Show/Hide the Full List
mod site chr6:34245166-34245167:+ [9]
Sequence TGCCCTCCTGGACAAGGCTAACATCCCACTTAGCCGCACCC
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000311487.9; ENST00000401473.7; ENST00000447654.5; ENST00000347617.10; ENST00000374116.3
External Link RMBase: m6A_site_713519
mod ID: M6ASITE074676 Click to Show/Hide the Full List
mod site chr6:34245223-34245224:+ [8]
Sequence CCACTCCCTTGGTGGTGGGGACATTGCTCTCTGGGCTTTTG
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2
Seq Type List m6A-seq
Transcript ID List ENST00000401473.7; ENST00000311487.9; ENST00000347617.10; ENST00000447654.5; ENST00000374116.3
External Link RMBase: m6A_site_713520
mod ID: M6ASITE074677 Click to Show/Hide the Full List
mod site chr6:34245433-34245434:+ [8]
Sequence CCCAGGATTCCCCCAGCCAAACTGTCTTTGTCACCACGTGG
Motif Score 2.627720238
Cell/Tissue List HeLa; HepG2; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000401473.7; ENST00000311487.9; ENST00000447654.5; ENST00000374116.3; ENST00000347617.10
External Link RMBase: m6A_site_713521
mod ID: M6ASITE074678 Click to Show/Hide the Full List
mod site chr6:34245504-34245505:+ [8]
Sequence TAGTCCCCGTACTAGGTTGGACAGCCCCCTTCGGTTACAGG
Motif Score 3.643047619
Cell/Tissue List HeLa; hESC-HEK293T; HepG2; Huh7; AML
Seq Type List m6A-seq; MAZTER-seq; MeRIP-seq; miCLIP
Transcript ID List ENST00000311487.9; ENST00000401473.7; ENST00000374116.3; ENST00000347617.10; ENST00000447654.5
External Link RMBase: m6A_site_713522
mod ID: M6ASITE074679 Click to Show/Hide the Full List
mod site chr6:34245601-34245602:+ [9]
Sequence CCTCCGCCTGGGATCTGAGTACATATTGTGGTGATGGAGAT
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000311487.9; ENST00000401473.7; ENST00000347617.10; ENST00000374116.3; ENST00000447654.5
External Link RMBase: m6A_site_713523
mod ID: M6ASITE074680 Click to Show/Hide the Full List
mod site chr6:34245702-34245703:+ [10]
Sequence GGGGCTGCTCCCCTAACCCTACTTTGCTTCCGCCACTCAGC
Motif Score 2.500660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000311487.9; ENST00000347617.10; ENST00000374116.3; ENST00000447654.5; ENST00000401473.7
External Link RMBase: m6A_site_713524
mod ID: M6ASITE074681 Click to Show/Hide the Full List
mod site chr6:34245754-34245755:+ [9]
Sequence CCTCAGATGGGGCACCAATAACAAGGAGCTCACCCTGCCCG
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000447654.5; ENST00000311487.9; ENST00000374116.3; ENST00000347617.10; ENST00000401473.7
External Link RMBase: m6A_site_713525
mod ID: M6ASITE074682 Click to Show/Hide the Full List
mod site chr6:34245838-34245839:+ [9]
Sequence GTTCCATTTTTCCTCTGTTCACAAACTACCTCTGGACAGTT
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000374116.3; ENST00000401473.7; ENST00000311487.9; ENST00000347617.10; ENST00000447654.5
External Link RMBase: m6A_site_713526
mod ID: M6ASITE074683 Click to Show/Hide the Full List
mod site chr6:34245842-34245843:+ [11]
Sequence CATTTTTCCTCTGTTCACAAACTACCTCTGGACAGTTGTGT
Motif Score 2.627720238
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000401473.7; ENST00000347617.10; ENST00000447654.5; ENST00000374116.3; ENST00000311487.9
External Link RMBase: m6A_site_713527
mod ID: M6ASITE074684 Click to Show/Hide the Full List
mod site chr6:34245853-34245854:+ [8]
Sequence TGTTCACAAACTACCTCTGGACAGTTGTGTTGTTTTTTGTT
Motif Score 3.643047619
Cell/Tissue List HeLa; hESC-HEK293T; Huh7; AML
Seq Type List m6A-seq; MAZTER-seq; MeRIP-seq; miCLIP
Transcript ID List ENST00000311487.9; ENST00000347617.10; ENST00000401473.7; ENST00000447654.5; ENST00000374116.3
External Link RMBase: m6A_site_713528
mod ID: M6ASITE074685 Click to Show/Hide the Full List
mod site chr6:34245891-34245892:+ [10]
Sequence GTTCAATGTTCCATTCTTCGACATCCGTCATTGCTGCTGCT
Motif Score 2.865571429
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000347617.10; ENST00000401473.7; ENST00000374116.3; ENST00000447654.5; ENST00000311487.9
External Link RMBase: m6A_site_713529
mod ID: M6ASITE074686 Click to Show/Hide the Full List
mod site chr6:34245974-34245975:+ [10]
Sequence ACGATCCCCTCCCCCAAGATACTCTTTGTGGGGAAGAGGGG
Motif Score 2.53247619
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000374116.3; ENST00000311487.9; ENST00000401473.7; ENST00000447654.5; ENST00000347617.10
External Link RMBase: m6A_site_713530
mod ID: M6ASITE074687 Click to Show/Hide the Full List
mod site chr6:34246021-34246022:+ [10]
Sequence CATGGCAGGCTGGGTGACCGACTACCCCAGTCCCAGGGAAG
Motif Score 3.287565476
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000401473.7; ENST00000374116.3; ENST00000311487.9; ENST00000347617.10; ENST00000447654.5
External Link RMBase: m6A_site_713531
mod ID: M6ASITE074688 Click to Show/Hide the Full List
mod site chr6:34246201-34246202:+ [10]
Sequence CTGGTTTCCTATTTGCAGTTACTTGAATAAAAAAAATATCC
Motif Score 2.494845238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000401473.7; ENST00000447654.5; ENST00000347617.10; ENST00000311487.9; ENST00000374116.3
External Link RMBase: m6A_site_713532
Pseudouridine (Pseudo)
In total 2 m6A sequence/site(s) in this target gene
mod ID: PSESITE000233 Click to Show/Hide the Full List
mod site chr6:34245631-34245632:+ [12]
Sequence GTGATGGAGATGCAGTCACTTATTGTCCAGGTGAGGCCCAA
Transcript ID List ENST00000311487.9; ENST00000374116.3; ENST00000347617.10; ENST00000447654.5; ENST00000401473.7
External Link RMBase: Pseudo_site_4234
mod ID: PSESITE000234 Click to Show/Hide the Full List
mod site chr6:34246158-34246159:+ [12]
Sequence GGGGAGGGGTAGCCATGATTTGTCCCAGCCTGGGGCTCCCT
Transcript ID List ENST00000401473.7; ENST00000347617.10; ENST00000447654.5; ENST00000311487.9; ENST00000374116.3
External Link RMBase: Pseudo_site_4235