m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00351)

Target Name	Neurogenic locus notch homolog protein 1 (NOTCH1)
Synonyms	Notch 1; hN1; Translocation-associated notch protein TAN-1; NEXT; NICD; TAN1 Click to Show/Hide
Gene Name	NOTCH1
Chromosomal Location	9q34.3
Family	NOTCH family
Function	Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4(+) and CD8(+) cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Click to Show/Hide
Gene ID	4851
Uniprot ID	NOTC1_HUMAN
HGNC ID	HGNC:7881
KEGG ID	hsa:4851

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

NOTCH1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Fat mass and obesity-associated protein (FTO) [ERASER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by FTO*
Cell Line	253J cell line	Homo sapiens
Treatment: siFTO 253J cells Control: 253J cells		GSE150239
Regulation		logFC: 6.94E-01 p-value: 5.11E-07
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	In bladder cancer, the changes in m6A methylation level mainly appeared at 5' untranslated region (5' UTR) of MALAT1 and Neurogenic locus notch homolog protein 1 (NOTCH1) transcripts, and at 3' UTR of CSNK2A2 and ITGA6 transcripts, responding to the overexpression of FTO. SFPQ could influence the FTO-mediated m6A RNA demethylation, eventually affecting the gene expression.
Target Regulation	Down regulation
Responsed Disease	Bladder cancer		ICD-11: 2C94	Disease Info
Pathway Response	Notch signaling pathway			hsa04330
Cell Process	Cell proliferation
	Cell invasion
	Cell apoptosis
In-vitro Model	HT-1197	Recurrent bladder carcinoma	Homo sapiens	CVCL_1291
	HT-1376	Bladder carcinoma	Homo sapiens	CVCL_1292
In-vivo Model	BALB/cnu/nu mice (4-5 weeks old) were used for the xenograft experiment. The mice were randomly divided into 2 groups (n = 6 for each group) and injected with 5 × 10⁶ HT-1197 cells in control group or FTO plasmid group, respectively.

Methyltransferase-like 14 (METTL14) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL14*
Cell Line	MDA-MB-231	Homo sapiens
Treatment: siMETTL14 MDA-MB-231 cells Control: MDA-MB-231 cells		GSE81164
Regulation		logFC: -8.37E-01 p-value: 6.43E-03
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene			[2]
Response Summary	Mettl14 and m6A modification participate in the RNA stability of Neurogenic locus notch homolog protein 1 (NOTCH1) mRNA. Notch1 plays an essential role in bladder tumorigenesis and bladder TIC self-renewal.
Target Regulation	Down regulation
Responsed Disease	Bladder cancer	ICD-11: 2C94	Disease Info
Cell Process	Cell proliferation
	Self-renewal
	Cell metastasis
In-vitro Model	Primary bladder cancer cells (Obtained from bladder cancer patients)

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	LX2 cell line	Homo sapiens
Treatment: shMETTL3 LX2 cells Control: shLuc LX2 cells		GSE207909
Regulation		logFC: -6.68E-01 p-value: 1.32E-12
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[3]
Response Summary	METTL3-catalyzed m6A modification promotes Neurogenic locus notch homolog protein 1 (NOTCH1) expression and the activation of the Notch signaling pathway. Forced activation of Notch signaling pathway successfully rescues the growth, migration, and invasion capacities of METTL3-depleted ESCC cells.
Target Regulation	Up regulation
Responsed Disease	Esophageal squamous cell carcinoma		ICD-11: 2B70.1	Disease Info
Pathway Response	Notch signaling pathway			hsa04330
Cell Process	Cell migration
	Cell invasion
In-vitro Model	TE-9	Esophageal squamous cell carcinoma	Homo sapiens	CVCL_1767
	KYSE-30	Esophageal squamous cell carcinoma	Homo sapiens	CVCL_1351
In-vivo Model	For induction of ESCC, 4-week-old mice were treated with drinking water containing 50 ug/mL 4NQO (Sigma-Aldrich, USA) for 16 weeks and then given normal drinking water for another 4-5 weeks. Cre was activated by the intraperitoneal injection of tamoxifen (Sigma-Aldrich, USA) at a dose of 9 mg per 40 g body weight every other day for a total of three injections. For tumor measurement, mice were sacrificed, and the esophagus was dissected immediately. The surface areas of tumors were measured as described previously.

YTH domain-containing family protein 2 (YTHDF2) [READER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by YTHDF2*
Cell Line	Testis	Mus musculus
Treatment: YTHDF2 knockout mice testis Control: Mice testis		GSE147574
Regulation		logFC: 1.06E+00 p-value: 8.73E-04
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[4]
Response Summary	YTHDF2 inhibits Notch signaling by downregulating the Neurogenic locus notch homolog protein 1 (NOTCH1), HES1, and HES5 mRNA levels.
Target Regulation	Down regulation
Pathway Response	Notch signaling pathway			hsa04330
Cell Process	Extracellular stress
	Cell apoptosis
In-vitro Model	HeLa	Endocervical adenocarcinoma	Homo sapiens	CVCL_0030
	Jurkat	T acute lymphoblastic leukemia	Homo sapiens	CVCL_0065

Esophageal cancer [ICD-11: 2B70]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[3]
Response Summary	METTL3-catalyzed m6A modification promotes Neurogenic locus notch homolog protein 1 (NOTCH1) expression and the activation of the Notch signaling pathway. Forced activation of Notch signaling pathway successfully rescues the growth, migration, and invasion capacities of METTL3-depleted ESCC cells.
Responsed Disease	Esophageal squamous cell carcinoma [ICD-11: 2B70.1]
Target Regulator	Methyltransferase-like 3 (METTL3)		WRITER	Regulator Info
Target Regulation	Up regulation
Pathway Response	Notch signaling pathway			hsa04330
Cell Process	Cell migration
	Cell invasion
In-vitro Model	TE-9	Esophageal squamous cell carcinoma	Homo sapiens	CVCL_1767
	KYSE-30	Esophageal squamous cell carcinoma	Homo sapiens	CVCL_1351
In-vivo Model	For induction of ESCC, 4-week-old mice were treated with drinking water containing 50 ug/mL 4NQO (Sigma-Aldrich, USA) for 16 weeks and then given normal drinking water for another 4-5 weeks. Cre was activated by the intraperitoneal injection of tamoxifen (Sigma-Aldrich, USA) at a dose of 9 mg per 40 g body weight every other day for a total of three injections. For tumor measurement, mice were sacrificed, and the esophagus was dissected immediately. The surface areas of tumors were measured as described previously.

Bladder cancer [ICD-11: 2C94]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	In bladder cancer, the changes in m6A methylation level mainly appeared at 5' untranslated region (5' UTR) of MALAT1 and Neurogenic locus notch homolog protein 1 (NOTCH1) transcripts, and at 3' UTR of CSNK2A2 and ITGA6 transcripts, responding to the overexpression of FTO. SFPQ could influence the FTO-mediated m6A RNA demethylation, eventually affecting the gene expression.
Responsed Disease	Bladder cancer [ICD-11: 2C94]
Target Regulator	Fat mass and obesity-associated protein (FTO)		ERASER	Regulator Info
Target Regulation	Down regulation
Pathway Response	Notch signaling pathway			hsa04330
Cell Process	Cell proliferation
	Cell invasion
	Cell apoptosis
In-vitro Model	HT-1197	Recurrent bladder carcinoma	Homo sapiens	CVCL_1291
	HT-1376	Bladder carcinoma	Homo sapiens	CVCL_1292
In-vivo Model	BALB/cnu/nu mice (4-5 weeks old) were used for the xenograft experiment. The mice were randomly divided into 2 groups (n = 6 for each group) and injected with 5 × 10⁶ HT-1197 cells in control group or FTO plasmid group, respectively.
Experiment 2 Reporting the m6A-centered Disease Response				[2]
Response Summary	Mettl14 and m6A modification participate in the RNA stability of Neurogenic locus notch homolog protein 1 (NOTCH1) mRNA. Notch1 plays an essential role in bladder tumorigenesis and bladder TIC self-renewal.
Responsed Disease	Bladder cancer [ICD-11: 2C94]
Target Regulator	Methyltransferase-like 14 (METTL14)		WRITER	Regulator Info
Target Regulation	Down regulation
Cell Process	Cell proliferation
	Self-renewal
	Cell metastasis
In-vitro Model	Primary bladder cancer cells (Obtained from bladder cancer patients)

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03373		Crosstalk Info
Regulated Target	Histone H3 lysine 18 lactylation (H3K18la)
Crosstalk relationship	Histone modification → m6A
Disease	Esophageal Squamous Cell Carcinoma	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00351)

Neurogenic locus notch homolog protein 1 (NOTCH1)

N4-acetylcytidine (ac4C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000135		Click to Show/Hide the Full List
mod site	chr9:136496762-136496763:-
Sequence	TGCCGAACCAATACAACCCTCTGCGGGGGAGTGTGGCACCA
Cell/Tissue List	DLD1
Seq Type List	acRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: ac4C_site_1806

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE003291		Click to Show/Hide the Full List
mod site	chr9:136520661-136520662:-		[7]
Sequence	CACTGCAGCCTTGACCTCCCAGGCTAAAGCGATCCTTCTGC
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: RNA-editing_site_139062

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004508		Click to Show/Hide the Full List
mod site	chr9:136504994-136504995:-		[8]
Sequence	TGGACTGTGCGGAGCATGTACCCGAGAGGCTGGCGGCCGGC
Cell/Tissue List	lung
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1; ENST00000645828.1
External Link	RMBase: m5C_site_44141

N6-methyladenosine (m6A)

In total 103 m6A sequence/site(s) in this target gene
mod ID: M6ASITE090422		Click to Show/Hide the Full List
mod site	chr9:136494536-136494537:-		[9]
Sequence	AGTGTAGTTTACAGAAAAAGACTTTAAAAGTGATCTACATG
Motif Score	3.319380952
Cell/Tissue List	HeLa; AML
Seq Type List	m6A-seq; miCLIP
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847564
mod ID: M6ASITE090423		Click to Show/Hide the Full List
mod site	chr9:136495016-136495017:-		[9]
Sequence	GCTCCCGTGTTTTGTAGGAGACTTGCCAGAGCCGGGCACAT
Motif Score	3.319380952
Cell/Tissue List	HeLa; H1A; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; iSLK; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847565
mod ID: M6ASITE090424		Click to Show/Hide the Full List
mod site	chr9:136495052-136495053:-		[9]
Sequence	CCTGGGCCCCAGCTCGCGGGACCCGACCCCCCGTGGGCTCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; H1A; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; iSLK; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847566
mod ID: M6ASITE090425		Click to Show/Hide the Full List
mod site	chr9:136495115-136495116:-		[10]
Sequence	GCCCCAGCACCTCAGCCTGCACAGTGTCCCCCAGGTTCCGA
Motif Score	2.830589286
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847567
mod ID: M6ASITE090426		Click to Show/Hide the Full List
mod site	chr9:136495162-136495163:-		[9]
Sequence	CTACCCTTTTCTGGGGAAAGACACTGCCTGGGCTGACCCCG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; H1A; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; TIME; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847568
mod ID: M6ASITE090427		Click to Show/Hide the Full List
mod site	chr9:136495218-136495219:-		[9]
Sequence	GTCAAACATGAGATGTGTGGACTGTGGCACTTGCCTGGGTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; H1A; H1B; CD4T; HEK293A-TOA; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847569
mod ID: M6ASITE090428		Click to Show/Hide the Full List
mod site	chr9:136495233-136495234:-		[9]
Sequence	GTAGGCATCATGCATGTCAAACATGAGATGTGTGGACTGTG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; H1A; H1B; CD4T; HEK293A-TOA; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847570
mod ID: M6ASITE090429		Click to Show/Hide the Full List
mod site	chr9:136495598-136495599:-		[11]
Sequence	CTTTCCCCGACGCCCACCCAACCCCAAGCCAGCCCGGCCGC
Motif Score	2.153267857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847571
mod ID: M6ASITE090430		Click to Show/Hide the Full List
mod site	chr9:136495750-136495751:-		[12]
Sequence	TCTGTGTTTATAAAATATAAACAAAGATTCATGATTTATAA
Motif Score	2.20572619
Cell/Tissue List	HEK293T; hESCs; Huh7
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847572
mod ID: M6ASITE090431		Click to Show/Hide the Full List
mod site	chr9:136495821-136495822:-		[9]
Sequence	CTTTTATCTATTCTGAGAAAACAAGCAAGTTCTGAGAGCCA
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HEK293T; hESC-HEK293T; hESCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847573
mod ID: M6ASITE090432		Click to Show/Hide the Full List
mod site	chr9:136495842-136495843:-		[9]
Sequence	TTATCTGGCCCCAGGTAGAAACTTTTATCTATTCTGAGAAA
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HEK293T; A549; hESCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847574
mod ID: M6ASITE090433		Click to Show/Hide the Full List
mod site	chr9:136495891-136495892:-		[13]
Sequence	TACTTTTATTTTACACAGAAACACTGCCTTTTTATTTATAT
Motif Score	2.20572619
Cell/Tissue List	CD34; HEK293T; HeLa; A549; hESC-HEK293T; hNPCs; hESCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847575
mod ID: M6ASITE090434		Click to Show/Hide the Full List
mod site	chr9:136495971-136495972:-		[13]
Sequence	ACCAGAGGAGCCTTTTTAAAACACATGTTTTTATACAAAAT
Motif Score	2.20572619
Cell/Tissue List	CD34; HEK293T; HeLa; A549; GM12878; peripheral-blood; HEK293A-TOA; MSC; TIME; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847576
mod ID: M6ASITE090435		Click to Show/Hide the Full List
mod site	chr9:136496052-136496053:-		[9]
Sequence	TAAACGGCGCGCCCCACGAGACCCCGGCTTCCTTTCCCAAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HEK293T; MT4; CD4T; peripheral-blood; TIME; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847577
mod ID: M6ASITE090436		Click to Show/Hide the Full List
mod site	chr9:136496232-136496233:-		[10]
Sequence	AACACCCCCAGCCACCAGCTACAGGTGCCTGAGCACCCCTT
Motif Score	2.078666667
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847578
mod ID: M6ASITE090437		Click to Show/Hide the Full List
mod site	chr9:136496254-136496255:-		[9]
Sequence	CAGCTACTCCTCGCCTGTGGACAACACCCCCAGCCACCAGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; HEK293T; hESC-HEK293T; H1A; H1B; hESCs; fibroblasts; A549; GM12878; LCLs; MT4; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847579
mod ID: M6ASITE090438		Click to Show/Hide the Full List
mod site	chr9:136496536-136496537:-		[9]
Sequence	GCAGAACCTGCAGCCAGCAAACATCCAGCAGCAGCAAAGCC
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HepG2; H1B; hNPCs; hESCs; A549; MT4; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847580
mod ID: M6ASITE090439		Click to Show/Hide the Full List
mod site	chr9:136496551-136496552:-		[9]
Sequence	CTTACAGATGCAGCAGCAGAACCTGCAGCCAGCAAACATCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; H1B; hNPCs; hESCs; A549; MT4; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847581
mod ID: M6ASITE090440		Click to Show/Hide the Full List
mod site	chr9:136496568-136496569:-		[11]
Sequence	CAGGTGCAGCCACAAAACTTACAGATGCAGCAGCAGAACCT
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847582
mod ID: M6ASITE090441		Click to Show/Hide the Full List
mod site	chr9:136496572-136496573:-		[9]
Sequence	CCAGCAGGTGCAGCCACAAAACTTACAGATGCAGCAGCAGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HepG2; U2OS; H1B; hNPCs; hESCs; A549; CD8T; MT4; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847583
mod ID: M6ASITE090442		Click to Show/Hide the Full List
mod site	chr9:136496594-136496595:-		[9]
Sequence	CCCAGCCTCACCTGGTGCAGACCCAGCAGGTGCAGCCACAA
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; H1B; hNPCs; hESCs; A549; MT4; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847584
mod ID: M6ASITE090443		Click to Show/Hide the Full List
mod site	chr9:136496776-136496777:-		[9]
Sequence	GCAGAGCGGCATGGTGCCGAACCAATACAACCCTCTGCGGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; A549; HepG2; H1A; H1B; hESCs; GM12878; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847585
mod ID: M6ASITE090444		Click to Show/Hide the Full List
mod site	chr9:136496936-136496937:-		[9]
Sequence	GCGGCCGGCTGGCCTTTGAGACTGGCCCACCTCGTCTCTCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847586
mod ID: M6ASITE090445		Click to Show/Hide the Full List
mod site	chr9:136497136-136497137:-		[9]
Sequence	CGGCATGCTCTCGCCCGTGGACTCCCTGGAGTCACCCCATG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847587
mod ID: M6ASITE090446		Click to Show/Hide the Full List
mod site	chr9:136497163-136497164:-		[9]
Sequence	CGGCAAGGGCTGCCTGCTGGACAGCTCCGGCATGCTCTCGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847588
mod ID: M6ASITE090447		Click to Show/Hide the Full List
mod site	chr9:136497214-136497215:-		[9]
Sequence	TGGAAGCAAGGAGGCCAAGGACCTCAAGGCACGGAGGAAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847589
mod ID: M6ASITE090448		Click to Show/Hide the Full List
mod site	chr9:136497442-136497443:-		[10]
Sequence	TATGGACCGCCTGCCGCGCGACATCGCACAGGAGCGCATGC
Motif Score	2.865571429
Cell/Tissue List	liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847590
mod ID: M6ASITE090449		Click to Show/Hide the Full List
mod site	chr9:136497457-136497458:-		[9]
Sequence	GGACATCACGGATCATATGGACCGCCTGCCGCGCGACATCG
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; A549; GM12878; MT4; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847591
mod ID: M6ASITE090450		Click to Show/Hide the Full List
mod site	chr9:136497475-136497476:-		[9]
Sequence	GGACCACTTTGCCAACCGGGACATCACGGATCATATGGACC
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; HepG2; MT4; peripheral-blood; HEK293A-TOA; iSLK; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847592
mod ID: M6ASITE090451		Click to Show/Hide the Full List
mod site	chr9:136497493-136497494:-		[9]
Sequence	GACCGCCAAGGTGCTGCTGGACCACTTTGCCAACCGGGACA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; MT4; peripheral-blood; iSLK; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847593
mod ID: M6ASITE090452		Click to Show/Hide the Full List
mod site	chr9:136497512-136497513:-		[9]
Sequence	CCCGGGAGGGCAGCTACGAGACCGCCAAGGTGCTGCTGGAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; MT4; peripheral-blood; iSLK; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847594
mod ID: M6ASITE090453		Click to Show/Hide the Full List
mod site	chr9:136497551-136497552:-		[9]
Sequence	CCCTCATCCCCCAGGAGGAGACACCCCTGTTTCTGGCCGCC
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; HepG2; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847595
mod ID: M6ASITE090454		Click to Show/Hide the Full List
mod site	chr9:136498905-136498906:-		[9]
Sequence	GGCTAACAAAGATATGCAGAACAACAGGGTGAGCGCGAGGC
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; HepG2; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847596
mod ID: M6ASITE090455		Click to Show/Hide the Full List
mod site	chr9:136498962-136498963:-		[9]
Sequence	GCACTGGGCCGCCGCCGTGAACAATGTGGATGCCGCAGTTG
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847597
mod ID: M6ASITE090456		Click to Show/Hide the Full List
mod site	chr9:136499155-136499156:-		[9]
Sequence	CGTGGAGGGCATGCTGGAGGACCTCATCAACTCACACGCCG
Motif Score	3.622404762
Cell/Tissue List	HeLa; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847598
mod ID: M6ASITE090457		Click to Show/Hide the Full List
mod site	chr9:136499233-136499234:-		[9]
Sequence	GATCCGGAACCGAGCCACAGACCTGGATGCCCGCATGCATG
Motif Score	2.876744048
Cell/Tissue List	HeLa; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847599
mod ID: M6ASITE090458		Click to Show/Hide the Full List
mod site	chr9:136499245-136499246:-		[9]
Sequence	TGCCCAGATCCTGATCCGGAACCGAGCCACAGACCTGGATG
Motif Score	2.930744048
Cell/Tissue List	HeLa; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847600
mod ID: M6ASITE090459		Click to Show/Hide the Full List
mod site	chr9:136500612-136500613:-		[9]
Sequence	CGCAGATGCCAACATCCAGGACAACATGGGCCGCACCCCGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847601
mod ID: M6ASITE090460		Click to Show/Hide the Full List
mod site	chr9:136500697-136500698:-		[9]
Sequence	AGACAGACCGCACGGGCGAGACCGCCTTGCACCTGGCCGCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847602
mod ID: M6ASITE090461		Click to Show/Hide the Full List
mod site	chr9:136500715-136500716:-		[9]
Sequence	GCGCCAGCCTGCACAACCAGACAGACCGCACGGGCGAGACC
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847603
mod ID: M6ASITE090462		Click to Show/Hide the Full List
mod site	chr9:136501855-136501856:-		[9]
Sequence	AGACAGACCACCGGCAGTGGACTCAGCAGCACCTGGATGCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; Jurkat; CD4T; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847604
mod ID: M6ASITE090463		Click to Show/Hide the Full List
mod site	chr9:136501873-136501874:-		[9]
Sequence	TGCCTGACCTGGACGACCAGACAGACCACCGGCAGTGGACT
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; Jurkat; CD4T; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847605
mod ID: M6ASITE090464		Click to Show/Hide the Full List
mod site	chr9:136502014-136502015:-		[9]
Sequence	GGGGGGACGAGGACCTGGAGACCAAGAAGTTCCGGGTGAGT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847606
mod ID: M6ASITE090465		Click to Show/Hide the Full List
mod site	chr9:136502022-136502023:-		[9]
Sequence	GAATGAGTGGGGGGACGAGGACCTGGAGACCAAGAAGTTCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847607
mod ID: M6ASITE090466		Click to Show/Hide the Full List
mod site	chr9:136502286-136502287:-		[9]
Sequence	GCGGGAGCCCCTCGGCGAGGACTCCGTGGGCCTCAAGTGAG
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847608
mod ID: M6ASITE090467		Click to Show/Hide the Full List
mod site	chr9:136502482-136502483:-		[9]
Sequence	CCCCCGTGCCCGCAGGTGAGACCGTGGAGCCGCCCCCGCCG
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7; ENST00000645828.1; ENST00000494783.1
External Link	RMBase: m6A_site_847609
mod ID: M6ASITE090468		Click to Show/Hide the Full List
mod site	chr9:136504690-136504691:-		[9]
Sequence	GCGGCGGCGGAGGGAGCTGGACCCCATGGACGTCCGCGGGT
Motif Score	3.622404762
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000645828.1; ENST00000494783.1; ENST00000277541.7
External Link	RMBase: m6A_site_847610
mod ID: M6ASITE090469		Click to Show/Hide the Full List
mod site	chr9:136505011-136505012:-		[9]
Sequence	GTGCGAGTGGGACGGGCTGGACTGTGCGGAGCATGTACCCG
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; H1A; H1B; hESCs; CD8T; Jurkat; CD4T; peripheral-blood; GSC-11; TIME; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; m6A-CLIP/IP; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000645828.1; ENST00000651671.1
External Link	RMBase: m6A_site_847611
mod ID: M6ASITE090470		Click to Show/Hide the Full List
mod site	chr9:136505077-136505078:-		[9]
Sequence	GTACGACCAGTACTGCAAGGACCACTTCAGCGACGGGCACT
Motif Score	3.622404762
Cell/Tissue List	HeLa; H1B; hESCs; Jurkat; CD4T; peripheral-blood; GSC-11; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000645828.1; ENST00000651671.1
External Link	RMBase: m6A_site_847612
mod ID: M6ASITE090471		Click to Show/Hide the Full List
mod site	chr9:136505429-136505430:-		[9]
Sequence	CTTCAATGACCCCTGGAAGAACTGCACGCAGTCTCTGCAGT
Motif Score	3.373380952
Cell/Tissue List	HeLa; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1; ENST00000645828.1
External Link	RMBase: m6A_site_847613
mod ID: M6ASITE090472		Click to Show/Hide the Full List
mod site	chr9:136505609-136505610:-		[9]
Sequence	GCTCTTGTGCCACATCCTGGACTACAGCTTCGGGGGTGGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847614
mod ID: M6ASITE090473		Click to Show/Hide the Full List
mod site	chr9:136505691-136505692:-		[9]
Sequence	ACCCCTGCTACAACCAGGGGACCTGTGAGCCCACATCCGAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7; ENST00000645828.1
External Link	RMBase: m6A_site_847615
mod ID: M6ASITE090474		Click to Show/Hide the Full List
mod site	chr9:136506768-136506769:-		[9]
Sequence	CGACGCCCGTGGCACCCAGAACTGCGTGCAGCGCGTCAATG
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847616
mod ID: M6ASITE090475		Click to Show/Hide the Full List
mod site	chr9:136506879-136506880:-		[9]
Sequence	TAACAACGGCACCTGCGTGGACCAGGTGGGCGGCTACAGCT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000645828.1; ENST00000651671.1
External Link	RMBase: m6A_site_847617
mod ID: M6ASITE090476		Click to Show/Hide the Full List
mod site	chr9:136507411-136507412:-		[9]
Sequence	GGCCGGCTACCACGGGGTGAACTGCTCTGAGGAGATCGACG
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847618
mod ID: M6ASITE090477		Click to Show/Hide the Full List
mod site	chr9:136507979-136507980:-		[9]
Sequence	GAACGGGGCCACCTGCACGGACTACCTGGGCGGCTACTCCT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1; ENST00000645828.1
External Link	RMBase: m6A_site_847619
mod ID: M6ASITE090478		Click to Show/Hide the Full List
mod site	chr9:136508033-136508034:-		[9]
Sequence	CACAGGCAGCTACTGTGAGGACCTGGTGGACGAGTGCTCAC
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000645828.1; ENST00000651671.1
External Link	RMBase: m6A_site_847620
mod ID: M6ASITE090479		Click to Show/Hide the Full List
mod site	chr9:136508288-136508289:-		[9]
Sequence	GCGAGTGCCCCAGCGGCTGGACCGGCCTTTACTGCGACGTG
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847621
mod ID: M6ASITE090480		Click to Show/Hide the Full List
mod site	chr9:136508327-136508328:-		[9]
Sequence	ACGGCGGCAAATGCTGGCAGACCCACACCCAGTACCGCTGC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000645828.1; ENST00000277541.7
External Link	RMBase: m6A_site_847622
mod ID: M6ASITE090481		Click to Show/Hide the Full List
mod site	chr9:136509756-136509757:-		[9]
Sequence	CAGCGGGATCCACTGTGAGAACAACACGCCTGACTGCACAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1; ENST00000645828.1
External Link	RMBase: m6A_site_847623
mod ID: M6ASITE090482		Click to Show/Hide the Full List
mod site	chr9:136509807-136509808:-		[9]
Sequence	CAACTGCACGGACTGCGTGGACAGCTACACGTGCACCTGCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847624
mod ID: M6ASITE090483		Click to Show/Hide the Full List
mod site	chr9:136509816-136509817:-		[9]
Sequence	CAACGGGGCCAACTGCACGGACTGCGTGGACAGCTACACGT
Motif Score	4.065041667
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000645828.1; ENST00000277541.7
External Link	RMBase: m6A_site_847625
mod ID: M6ASITE090484		Click to Show/Hide the Full List
mod site	chr9:136509867-136509868:-		[9]
Sequence	GGGCACTTTCTGTGAGGAGGACATCAACGAGTGTGCCAGTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847626
mod ID: M6ASITE090485		Click to Show/Hide the Full List
mod site	chr9:136510676-136510677:-		[9]
Sequence	ACAGTGGGCGCAACTGCGAGACCGACATCGACGACTGCCGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD4T; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000645828.1; ENST00000646957.1; ENST00000651671.1
External Link	RMBase: m6A_site_847627
mod ID: M6ASITE090486		Click to Show/Hide the Full List
mod site	chr9:136510735-136510736:-		[9]
Sequence	GCACGGCGCATCCTGCCAGAACACCCACGGCGGCTACCGCT
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD4T; peripheral-blood; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000646957.1; ENST00000645828.1; ENST00000277541.7
External Link	RMBase: m6A_site_847628
mod ID: M6ASITE090487		Click to Show/Hide the Full List
mod site	chr9:136510799-136510800:-		[9]
Sequence	CCTCCTGCCCCGCAGGGCAGACCTGTGAGGTCGACATCAAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD4T; peripheral-blood; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000646957.1; ENST00000277541.7; ENST00000645828.1
External Link	RMBase: m6A_site_847629
mod ID: M6ASITE090488		Click to Show/Hide the Full List
mod site	chr9:136511192-136511193:-		[9]
Sequence	GGAGTGCAGGCAATCCGAGGACTATGAGAGCTTCTCCTGTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000645828.1; ENST00000646957.1; ENST00000277541.7
External Link	RMBase: m6A_site_847630
mod ID: M6ASITE090489		Click to Show/Hide the Full List
mod site	chr9:136513049-136513050:-		[14]
Sequence	TATTGACGACGTTGCCGGGTACAAGTGCAACTGCCTGCTGC
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1; ENST00000646957.1; ENST00000645828.1
External Link	RMBase: m6A_site_847631
mod ID: M6ASITE090490		Click to Show/Hide the Full List
mod site	chr9:136513082-136513083:-		[9]
Sequence	TGCGTCCAACCCATGTCTGAACCAGGGCACGTGTATTGACG
Motif Score	2.930744048
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7; ENST00000645828.1; ENST00000646957.1
External Link	RMBase: m6A_site_847632
mod ID: M6ASITE090491		Click to Show/Hide the Full List
mod site	chr9:136513115-136513116:-		[14]
Sequence	AGGTCCCAACTGCCAGACCAACATCAACGAGTGTGCGTCCA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000645828.1; rmsk_2902491; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847633
mod ID: M6ASITE090492		Click to Show/Hide the Full List
mod site	chr9:136513119-136513120:-		[9]
Sequence	CTCCAGGTCCCAACTGCCAGACCAACATCAACGAGTGTGCG
Motif Score	2.876744048
Cell/Tissue List	HeLa; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000645828.1; ENST00000277541.7; ENST00000651671.1; rmsk_2902491
External Link	RMBase: m6A_site_847634
mod ID: M6ASITE090493		Click to Show/Hide the Full List
mod site	chr9:136513435-136513436:-		[9]
Sequence	CAACGGCGGCACCTGCAAAGACATGACCAGTGGCTACGTGT
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T; CD4T; peripheral-blood; endometrial
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7; ENST00000645828.1
External Link	RMBase: m6A_site_847635
mod ID: M6ASITE090494		Click to Show/Hide the Full List
mod site	chr9:136513483-136513484:-		[14]
Sequence	GACCAACTGTGACATCAACAACAATGAGTGTGAATCCAACC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000645828.1; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847636
mod ID: M6ASITE090495		Click to Show/Hide the Full List
mod site	chr9:136513502-136513503:-		[9]
Sequence	GTGACCCTGGGTGGAGTGGGACCAACTGTGACATCAACAAC
Motif Score	3.622404762
Cell/Tissue List	HeLa; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000645828.1; ENST00000277541.7
External Link	RMBase: m6A_site_847637
mod ID: M6ASITE090496		Click to Show/Hide the Full List
mod site	chr9:136514521-136514522:-		[9]
Sequence	CGTCCACGGGGCCTGCCGGGACAGCCTCAACGGGTATGCGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847638
mod ID: M6ASITE090497		Click to Show/Hide the Full List
mod site	chr9:136515333-136515334:-		[9]
Sequence	CGACTCGGGCACCTGTCTGGACAAGATCGATGGCTACGAGT
Motif Score	3.643047619
Cell/Tissue List	HeLa; MT4; peripheral-blood; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847639
mod ID: M6ASITE090498		Click to Show/Hide the Full List
mod site	chr9:136515488-136515489:-		[9]
Sequence	TCTGCTTCTGCCTGAAGGGGACCACAGGTGGCCGGCCAGGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847640
mod ID: M6ASITE090499		Click to Show/Hide the Full List
mod site	chr9:136515526-136515527:-		[9]
Sequence	CCACGGGGGCACCTGCCAGGACCGCGACAACGCCTACCTCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847641
mod ID: M6ASITE090500		Click to Show/Hide the Full List
mod site	chr9:136515581-136515582:-		[9]
Sequence	ACACGGGCCACCACTGCGAGACCAACATCAACGAGTGCTCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847642
mod ID: M6ASITE090501		Click to Show/Hide the Full List
mod site	chr9:136515688-136515689:-		[9]
Sequence	GGGGACGCACTGCGAGGTGGACATCGATGAGTGCGACCCCG
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847643
mod ID: M6ASITE090502		Click to Show/Hide the Full List
mod site	chr9:136516011-136516012:-		[9]
Sequence	GGTGCCAAGTGCCTGGACGGACCCAACACTTACACCTGTGT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847644
mod ID: M6ASITE090503		Click to Show/Hide the Full List
mod site	chr9:136517306-136517307:-		[9]
Sequence	GCACAATGGCCGCTGCCTGGACAAGATCAATGAGTTCCAGT
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847645
mod ID: M6ASITE090504		Click to Show/Hide the Full List
mod site	chr9:136517786-136517787:-		[9]
Sequence	GAACGACGCCACCTGCCTGGACCAGATTGGGGAGTTCCAGT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847646
mod ID: M6ASITE090505		Click to Show/Hide the Full List
mod site	chr9:136517816-136517817:-		[9]
Sequence	CGTCAACGAGTGCGTCTCGAACCCGTGCCAGAACGACGCCA
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847647
mod ID: M6ASITE090506		Click to Show/Hide the Full List
mod site	chr9:136518685-136518686:-		[9]
Sequence	TGGTGAGGACTGCAGCGAGAACATTGATGACTGTGCCAGCG
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T; peripheral-blood
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847648
mod ID: M6ASITE090507		Click to Show/Hide the Full List
mod site	chr9:136518697-136518698:-		[9]
Sequence	CAACGGCTGGACTGGTGAGGACTGCAGCGAGAACATTGATG
Motif Score	4.065041667
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847649
mod ID: M6ASITE090508		Click to Show/Hide the Full List
mod site	chr9:136518707-136518708:-		[9]
Sequence	GCGTGTGTGTCAACGGCTGGACTGGTGAGGACTGCAGCGAG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847650
mod ID: M6ASITE090509		Click to Show/Hide the Full List
mod site	chr9:136518733-136518734:-		[14]
Sequence	CCACAACACCCACGGTGGCTACAACTGCGTGTGTGTCAACG
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847651
mod ID: M6ASITE090510		Click to Show/Hide the Full List
mod site	chr9:136518751-136518752:-		[14]
Sequence	CCAGAACGGCGGGACCTGCCACAACACCCACGGTGGCTACA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847652
mod ID: M6ASITE090511		Click to Show/Hide the Full List
mod site	chr9:136518758-136518759:-		[9]
Sequence	ATGCCTGCCAGAACGGCGGGACCTGCCACAACACCCACGGT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847653
mod ID: M6ASITE090512		Click to Show/Hide the Full List
mod site	chr9:136519445-136519446:-		[9]
Sequence	GCCGCTGCCCGCCAGAGTGGACAGGCGCGTATACGGGTCGC
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847654
mod ID: M6ASITE090513		Click to Show/Hide the Full List
mod site	chr9:136519477-136519478:-		[9]
Sequence	TGCCTGTGTGGACGGCGTGAACACCTACAACTGCCGCTGCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847655
mod ID: M6ASITE090514		Click to Show/Hide the Full List
mod site	chr9:136519516-136519517:-		[9]
Sequence	TATCGACGATTGTCCAGGAAACAACTGCAAGAACGGGGGTG
Motif Score	2.20572619
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847656
mod ID: M6ASITE090515		Click to Show/Hide the Full List
mod site	chr9:136519549-136519550:-		[9]
Sequence	GGCAGGCTTCACCGGCCAGAACTGTGAGGAAAATATCGACG
Motif Score	3.373380952
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847657
mod ID: M6ASITE090516		Click to Show/Hide the Full List
mod site	chr9:136522706-136522707:-		[9]
Sequence	CGGGATGGCGAGTTCCCCAGACTGCGTGTGGTGTCGGGGGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; MT4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000491649.1; ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847658
mod ID: M6ASITE090517		Click to Show/Hide the Full List
mod site	chr9:136523811-136523812:-		[9]
Sequence	CCTCTGCCTGACACCCCTGGACAATGCCTGCCTCACCAACC
Motif Score	3.643047619
Cell/Tissue List	HeLa; peripheral-blood; GSC-11; iSLK; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000491649.1; ENST00000651671.1
External Link	RMBase: m6A_site_847659
mod ID: M6ASITE090518		Click to Show/Hide the Full List
mod site	chr9:136523868-136523869:-		[9]
Sequence	GGACCGCAGAGGCGTGGCAGACTATGCCTGCAGCTGTGCCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; peripheral-blood; GSC-11; iSLK; MSC; TIME; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000491649.1; ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847660
mod ID: M6ASITE090519		Click to Show/Hide the Full List
mod site	chr9:136523886-136523887:-		[9]
Sequence	CGGGACATGCCACGTGGTGGACCGCAGAGGCGTGGCAGACT
Motif Score	3.622404762
Cell/Tissue List	HeLa; peripheral-blood; GSC-11; iSLK; TIME; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000491649.1; ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847661
mod ID: M6ASITE090520		Click to Show/Hide the Full List
mod site	chr9:136523902-136523903:-		[9]
Sequence	CCCCCTGCAAGAACGCCGGGACATGCCACGTGGTGGACCGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; peripheral-blood; GSC-11; iSLK; TIME; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000277541.7; ENST00000651671.1
External Link	RMBase: m6A_site_847662
mod ID: M6ASITE090521		Click to Show/Hide the Full List
mod site	chr9:136523943-136523944:-		[9]
Sequence	CGTGGGCCCGCGATGCCAGGACCCCAACCCGTGCCTCAGCA
Motif Score	3.622404762
Cell/Tissue List	HeLa; MT4; CD4T; peripheral-blood; GSC-11; iSLK; TIME; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847663
mod ID: M6ASITE090522		Click to Show/Hide the Full List
mod site	chr9:136544075-136544076:-		[9]
Sequence	GATGCTCCCAGCCCGGTGAGACCTGCCTGAATGGCGGGAAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; A549; MT4; GSC-11; iSLK; TIME; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1; ENST00000277541.7
External Link	RMBase: m6A_site_847666
mod ID: M6ASITE090523		Click to Show/Hide the Full List
mod site	chr9:136545871-136545872:-		[15]
Sequence	CCGTCCGCCGCCGCCCCGGGACCGTACGCCGCGCGTGTGCG
Motif Score	3.622404762
Cell/Tissue List	Jurkat; GSC-11; HEK293T; HEK293A-TOA; iSLK; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1
External Link	RMBase: m6A_site_847667
mod ID: M6ASITE090524		Click to Show/Hide the Full List
mod site	chr9:136545892-136545893:-		[15]
Sequence	GCCGGGGAAGAGAGGGCGGGACCGTCCGCCGCCGCCCCGGG
Motif Score	3.622404762
Cell/Tissue List	Jurkat; GSC-11; HEK293T; HEK293A-TOA; iSLK; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651671.1
External Link	RMBase: m6A_site_847668

Ref 1	The tumor-suppressive effects of alpha-ketoglutarate-dependent dioxygenase FTO via N6-methyladenosine RNA methylation on bladder cancer patients. Bioengineered. 2021 Dec;12(1):5323-5333. doi: 10.1080/21655979.2021.1964893.
Ref 2	Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N(6)-methyladenosine of Notch1. Mol Cancer. 2019 Nov 25;18(1):168. doi: 10.1186/s12943-019-1084-1.
Ref 3	METTL3-mediated m(6)A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway. Mol Ther Nucleic Acids. 2021 Jul 21;26:333-346. doi: 10.1016/j.omtn.2021.07.007. eCollection 2021 Dec 3.
Ref 4	YTHDF2 Suppresses Notch Signaling through Post-transcriptional Regulation on Notch1. Int J Biol Sci. 2021 Aug 28;17(14):3776-3785. doi: 10.7150/ijbs.61573. eCollection 2021.
Ref 5	Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1793-7. doi: 10.1016/j.bmcl.2005.02.039.
Ref 6	ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram. Int J Legal Med. 2013 May;127(3):579-86. doi: 10.1007/s00414-013-0849-0. Epub 2013 Mar 21.
Ref 7	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 8	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 9	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 10	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 11	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 12	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 13	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 14	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 15	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Elife. 2016 Jul 2;5:e15528. doi: 10.7554/eLife.15528.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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