m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00184)

Target Name	ATPase family AAA domain-containing protein 3A (ATAD3A)
Gene Name	ATAD3A
Chromosomal Location	1p36.33
Family	AAA ATPase family
Function	Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. Involved in mitochondrial-mediated antiviral innate immunity. Click to Show/Hide
Gene ID	55210
Uniprot ID	ATD3A_HUMAN
HGNC ID	HGNC:25567
KEGG ID	hsa:55210

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

ATAD3A can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

RNA-binding motif protein 15 (RBM15) [WRITER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	RBM15-mediated m6A modification of TMBIM6 mRNA enhanced TMBIM6 stability through IGF2BP3-dependent. Laryngeal squamous cell cancer cells were transfected with shRBM15 lentivirus for 48h, and the qRT-PCR data indicated that the mRNA levels of CPNE5, TMBIM6, and ATPase family AAA domain-containing protein 3A (ATAD3A) decreased after RBM15 knockdown.
Target Regulation	Up regulation
Responsed Disease	Laryngeal cancer		ICD-11: 2C23	Disease Info
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	AMC-HN-8	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_5966
	NHBEC (Normal human bronchial epithelial cell)
	Tu 177	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_4913
	Tu 212	Head and neck squamous cell carcinoma	Homo sapiens	CVCL_4915
In-vivo Model	For tumor growth studies, whether in vivo RBM15 knockdown/overexpression experiments or in vivo rescue experiments, each group included six mice. Each mouse was injected with 100 uL of lentivirus-transfected tumor cells.

Laryngeal cancer [ICD-11: 2C23]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	RBM15-mediated m6A modification of TMBIM6 mRNA enhanced TMBIM6 stability through IGF2BP3-dependent. Laryngeal squamous cell cancer cells were transfected with shRBM15 lentivirus for 48h, and the qRT-PCR data indicated that the mRNA levels of CPNE5, TMBIM6, and ATPase family AAA domain-containing protein 3A (ATAD3A) decreased after RBM15 knockdown.
Responsed Disease	Laryngeal cancer [ICD-11: 2C23]
Target Regulator	RNA-binding motif protein 15 (RBM15)		WRITER	Regulator Info
Target Regulation	Up regulation
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	AMC-HN-8	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_5966
	NHBEC (Normal human bronchial epithelial cell)
	Tu 177	Laryngeal squamous cell carcinoma	Homo sapiens	CVCL_4913
	Tu 212	Head and neck squamous cell carcinoma	Homo sapiens	CVCL_4915
In-vivo Model	For tumor growth studies, whether in vivo RBM15 knockdown/overexpression experiments or in vivo rescue experiments, each group included six mice. Each mouse was injected with 100 uL of lentivirus-transfected tumor cells.

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00184)

ATPase family AAA domain-containing protein 3A (ATAD3A)

Adenosine-to-Inosine editing (A-to-I)

In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE005118		Click to Show/Hide the Full List
mod site	chr1:1521854-1521855:+		[2]
Sequence	GATTACAGGCTCACGTCACCACACTCAGCTAATATAGGCCT
Transcript ID List	ENST00000429957.1; ENST00000378756.7; ENST00000536055.5; ENST00000378755.9; ENST00000339113.8
External Link	RMBase: RNA-editing_site_237
mod ID: A2ISITE005119		Click to Show/Hide the Full List
mod site	chr1:1530940-1530941:+		[2]
Sequence	GTGAGAATATCATACACCTGAGGTCAGGAGTTTGAGAGCAG
Transcript ID List	rmsk_3289; ENST00000378755.9; ENST00000536055.5; ENST00000339113.8; ENST00000378756.7
External Link	RMBase: RNA-editing_site_238

N1-methyladenosine (m1A)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M1ASITE000063		Click to Show/Hide the Full List
mod site	chr1:1524381-1524382:+		[3]
Sequence	CAAGCTCTTTGACTGGGCCAATACCAGCCGGCGCGGGTGAG
Cell/Tissue List	HEK293T
Seq Type List	m1A-MAP-seq
Transcript ID List	ENST00000339113.8; ENST00000378755.9; ENST00000536055.5; ENST00000400830.3; ENST00000378756.7
External Link	RMBase: m1A_site_5

5-methylcytidine (m5C)

In total 5 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002567		Click to Show/Hide the Full List
mod site	chr1:1512438-1512439:+		[4]
Sequence	GACCCCACCGGCCTGGAGCGCGCCGCCAAGGCGGCGCGCGA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9
External Link	RMBase: m5C_site_283
mod ID: M5CSITE002576		Click to Show/Hide the Full List
mod site	chr1:1512440-1512441:+		[4]
Sequence	CCCCACCGGCCTGGAGCGCGCCGCCAAGGCGGCGCGCGAGC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000378755.9; ENST00000378756.7
External Link	RMBase: m5C_site_284
mod ID: M5CSITE002615		Click to Show/Hide the Full List
mod site	chr1:1512441-1512442:+		[4]
Sequence	CCCACCGGCCTGGAGCGCGCCGCCAAGGCGGCGCGCGAGCT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9
External Link	RMBase: m5C_site_285
mod ID: M5CSITE002672		Click to Show/Hide the Full List
mod site	chr1:1526604-1526605:+
Sequence	CCTTGGTTCCCACCGAGGGACCTGAGGGGCCCTGGCTCACA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000378756.7; ENST00000339113.8; ENST00000400830.3; ENST00000536055.5; ENST00000378755.9
External Link	RMBase: m5C_site_287
mod ID: M5CSITE002674		Click to Show/Hide the Full List
mod site	chr1:1528803-1528804:+
Sequence	CTCCATGCCAGCCCAGCTTTCCGGGCCTCAGTTTCCCTATG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9; ENST00000536055.5; ENST00000339113.8; ENST00000400830.3
External Link	RMBase: m5C_site_288

N6-methyladenosine (m6A)

In total 36 m6A sequence/site(s) in this target gene
mod ID: M6ASITE010869		Click to Show/Hide the Full List
mod site	chr1:1512221-1512222:+		[5]
Sequence	CCCAGCCGCGCGCGAGTCAGACTCGGGTGGGGGTCCCGGCG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; GSC-11; HEK293A-TOA; MSC; TREX; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9
External Link	RMBase: m6A_site_1778
mod ID: M6ASITE010870		Click to Show/Hide the Full List
mod site	chr1:1512290-1512291:+		[6]
Sequence	GTCGTGGCTCTTCGGCATTAACAAGGGCCCCAAGGGTGAAG
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9
External Link	RMBase: m6A_site_1779
mod ID: M6ASITE010871		Click to Show/Hide the Full List
mod site	chr1:1512368-1512369:+		[5]
Sequence	CGGGGCCGAGGGCGGCGGGGACCGCGGGTTGGGAGACCGGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000378755.9; ENST00000378756.7
External Link	RMBase: m6A_site_1780
mod ID: M6ASITE010872		Click to Show/Hide the Full List
mod site	chr1:1512383-1512384:+		[5]
Sequence	CGGGGACCGCGGGTTGGGAGACCGGCCGGCGCCCAAGGACA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9
External Link	RMBase: m6A_site_1781
mod ID: M6ASITE010873		Click to Show/Hide the Full List
mod site	chr1:1512401-1512402:+		[5]
Sequence	AGACCGGCCGGCGCCCAAGGACAAATGGAGCAACTTCGACC
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T; GSC-11
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000378755.9; ENST00000378756.7
External Link	RMBase: m6A_site_1782
mod ID: M6ASITE010874		Click to Show/Hide the Full List
mod site	chr1:1512585-1512586:+		[5]
Sequence	GCAGCCACTTCCCGGGCGAGACTGCGCCCCCGGAGCACCCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000378755.9; ENST00000536055.5; ENST00000339113.8; ENST00000378756.7
External Link	RMBase: m6A_site_1783
mod ID: M6ASITE010875		Click to Show/Hide the Full List
mod site	chr1:1512640-1512641:+		[5]
Sequence	TCGCGTGCCGGGAGGATCGGACTCTTTCCGTCACCCGTTTG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000339113.8; ENST00000378755.9; ENST00000536055.5; ENST00000378756.7
External Link	RMBase: m6A_site_1784
mod ID: M6ASITE010877		Click to Show/Hide the Full List
mod site	chr1:1517379-1517380:+		[5]
Sequence	AGGCTGAGGAGAGGAGGAAGACCCTGAGCGAGGAGACCCGG
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000439513.1; ENST00000339113.8; ENST00000378756.7; ENST00000378755.9; ENST00000536055.5
External Link	RMBase: m6A_site_1785
mod ID: M6ASITE010888		Click to Show/Hide the Full List
mod site	chr1:1517394-1517395:+		[5]
Sequence	GGAAGACCCTGAGCGAGGAGACCCGGCAGCACCAGGCCGTA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000339113.8; ENST00000536055.5; ENST00000439513.1; ENST00000378755.9; ENST00000378756.7
External Link	RMBase: m6A_site_1786
mod ID: M6ASITE010894		Click to Show/Hide the Full List
mod site	chr1:1517666-1517667:+		[5]
Sequence	GCTCCGCCCAGTCGGCCCAGACTGCAGCTCCCGGCTGAGAT
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9; ENST00000439513.1; ENST00000339113.8; ENST00000536055.5; ENST00000429957.1
External Link	RMBase: m6A_site_1787
mod ID: M6ASITE010895		Click to Show/Hide the Full List
mod site	chr1:1517731-1517732:+		[5]
Sequence	CCAGAGGGCCCAGTATCAAGACAAGCTGGCCCGGCAGCGCT
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000339113.8; ENST00000536055.5; ENST00000429957.1; ENST00000439513.1; ENST00000378755.9; ENST00000378756.7
External Link	RMBase: m6A_site_1788
mod ID: M6ASITE010896		Click to Show/Hide the Full List
mod site	chr1:1517758-1517759:+		[5]
Sequence	GGCCCGGCAGCGCTACGAGGACCAACTGAAGCAGCAGGTGA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000429957.1; ENST00000378756.7; ENST00000378755.9; ENST00000536055.5; ENST00000339113.8; ENST00000439513.1
External Link	RMBase: m6A_site_1789
mod ID: M6ASITE010897		Click to Show/Hide the Full List
mod site	chr1:1520170-1520171:+		[6]
Sequence	GCGGGAGATGGAGCTGCGGCACAAGAATGAGATGCTGCGAG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000536055.5; ENST00000339113.8; ENST00000378755.9; ENST00000429957.1; ENST00000378756.7
External Link	RMBase: m6A_site_1790
mod ID: M6ASITE010898		Click to Show/Hide the Full List
mod site	chr1:1520239-1520240:+		[5]
Sequence	GGCCGAGCGGGAGAATGCAGACATCATCCGCGAGCAGATCC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; U2OS; A549; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000536055.5; ENST00000429957.1; ENST00000378756.7; ENST00000339113.8; ENST00000378755.9
External Link	RMBase: m6A_site_1791
mod ID: M6ASITE010899		Click to Show/Hide the Full List
mod site	chr1:1520286-1520287:+		[5]
Sequence	AGGCGGCCGAGCACCGTCAGACCGTCTTGGAGTCCATCAGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; U2OS; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000378755.9; ENST00000536055.5; ENST00000339113.8; ENST00000429957.1; ENST00000378756.7
External Link	RMBase: m6A_site_1792
mod ID: M6ASITE010900		Click to Show/Hide the Full List
mod site	chr1:1520594-1520595:+		[5]
Sequence	ATTCCGTGCCTTTGTGACAGACTGGGACAAAGTGACAGCCA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000429957.1; ENST00000339113.8; ENST00000378756.7; ENST00000536055.5; ENST00000378755.9
External Link	RMBase: m6A_site_1793
mod ID: M6ASITE010946		Click to Show/Hide the Full List
mod site	chr1:1520600-1520601:+		[5]
Sequence	TGCCTTTGTGACAGACTGGGACAAAGTGACAGCCACGGTAA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000536055.5; ENST00000339113.8; ENST00000378756.7; ENST00000378755.9; ENST00000429957.1
External Link	RMBase: m6A_site_1794
mod ID: M6ASITE010947		Click to Show/Hide the Full List
mod site	chr1:1523884-1523885:+		[5]
Sequence	CATCGCCATAGCAACAAGGAACACCAAGAAGAACCGCAGCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; MT4; MM6; peripheral-blood; HEK293T; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000378756.7; ENST00000536055.5; ENST00000339113.8; ENST00000378755.9
External Link	RMBase: m6A_site_1795
mod ID: M6ASITE010948		Click to Show/Hide the Full List
mod site	chr1:1523896-1523897:+		[5]
Sequence	AACAAGGAACACCAAGAAGAACCGCAGCCTGTACAGGAACA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MT4; MM6; peripheral-blood; HEK293T; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000536055.5; ENST00000378755.9; ENST00000378756.7; ENST00000339113.8
External Link	RMBase: m6A_site_1796
mod ID: M6ASITE010993		Click to Show/Hide the Full List
mod site	chr1:1523914-1523915:+		[5]
Sequence	GAACCGCAGCCTGTACAGGAACATCCTGATGTACGGGCCAC
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; MT4; MM6; peripheral-blood; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000339113.8; ENST00000378755.9; ENST00000536055.5; ENST00000378756.7
External Link	RMBase: m6A_site_1797
mod ID: M6ASITE011094		Click to Show/Hide the Full List
mod site	chr1:1524274-1524275:+		[5]
Sequence	CTCACTCTTCCTGTCCAGAAACTCGCCCTGCACTCAGGCAT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000339113.8; ENST00000536055.5; ENST00000378755.9; ENST00000378756.7; ENST00000400830.3
External Link	RMBase: m6A_site_1798
mod ID: M6ASITE011137		Click to Show/Hide the Full List
mod site	chr1:1524297-1524298:+		[5]
Sequence	CGCCCTGCACTCAGGCATGGACTACGCCATCATGACAGGCG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000400830.3; ENST00000378756.7; ENST00000339113.8; ENST00000536055.5; ENST00000378755.9
External Link	RMBase: m6A_site_1799
mod ID: M6ASITE011231		Click to Show/Hide the Full List
mod site	chr1:1524360-1524361:+		[6]
Sequence	GGAAGGCGTGACCGCCATGCACAAGCTCTTTGACTGGGCCA
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000339113.8; ENST00000536055.5; ENST00000378755.9; ENST00000378756.7; ENST00000400830.3
External Link	RMBase: m6A_site_1800
mod ID: M6ASITE011252		Click to Show/Hide the Full List
mod site	chr1:1526476-1526477:+		[5]
Sequence	GCAGGAGAAGATAAGCGAGGACCTCAGGGCCACACTGAACG
Motif Score	3.622404762
Cell/Tissue List	HeLa; MT4; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9; ENST00000536055.5; ENST00000400830.3; ENST00000339113.8
External Link	RMBase: m6A_site_1801
mod ID: M6ASITE011295		Click to Show/Hide the Full List
mod site	chr1:1526487-1526488:+		[6]
Sequence	TAAGCGAGGACCTCAGGGCCACACTGAACGCCTTCCTGTAC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000400830.3; ENST00000378755.9; ENST00000339113.8; ENST00000378756.7; ENST00000536055.5
External Link	RMBase: m6A_site_1802
mod ID: M6ASITE011306		Click to Show/Hide the Full List
mod site	chr1:1526527-1526528:+		[6]
Sequence	CCGCACGGGCCAGCACAGCAACAAGTGAGGGAGCCCCTCGG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000378756.7; ENST00000378755.9; ENST00000339113.8; ENST00000400830.3; ENST00000536055.5
External Link	RMBase: m6A_site_1803
mod ID: M6ASITE011317		Click to Show/Hide the Full List
mod site	chr1:1527825-1527826:+		[6]
Sequence	CCTGGTGAGAATGTATTTTGACAAGTATGTTCTTAAGCCGG
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000378755.9; ENST00000378756.7; ENST00000400830.3; ENST00000339113.8; ENST00000536055.5
External Link	RMBase: m6A_site_1804
mod ID: M6ASITE011327		Click to Show/Hide the Full List
mod site	chr1:1533974-1533975:+		[5]
Sequence	CCTGACCGAGGCCATGATGGACACCCGCGTGCAAGATGCTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; MM6; peripheral-blood; HEC-1-A; NB4
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000536055.5; ENST00000378755.9; ENST00000378756.7; ENST00000339113.8
External Link	RMBase: m6A_site_1805
mod ID: M6ASITE011338		Click to Show/Hide the Full List
mod site	chr1:1534112-1534113:+		[5]
Sequence	CTCACGGAGCCTGGCCGCGGACCCCTCCCACCCCTGCCTTG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; MM6; peripheral-blood; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000536055.5; ENST00000339113.8; ENST00000378755.9; ENST00000378756.7
External Link	RMBase: m6A_site_1806
mod ID: M6ASITE011349		Click to Show/Hide the Full List
mod site	chr1:1534144-1534145:+		[6]
Sequence	CCTGCCTTGCCGGCCCCTGCACATTTAGGATATGCTCCTGG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000536055.5; ENST00000378756.7; ENST00000339113.8; ENST00000378755.9
External Link	RMBase: m6A_site_1807
mod ID: M6ASITE011360		Click to Show/Hide the Full List
mod site	chr1:1534171-1534172:+		[5]
Sequence	GGATATGCTCCTGGGTGGGGACTGGGCTGTGCCCAGGGCCT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; MM6; peripheral-blood; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000378755.9; ENST00000378756.7; ENST00000536055.5; ENST00000339113.8
External Link	RMBase: m6A_site_1808
mod ID: M6ASITE011368		Click to Show/Hide the Full List
mod site	chr1:1534300-1534301:+		[5]
Sequence	CCTCCTTCCTGCCCCTCGAGACACTCTTGGGAGATGCATTT
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T; TREX
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000339113.8; ENST00000536055.5; ENST00000378756.7; ENST00000378755.9
External Link	RMBase: m6A_site_1809
mod ID: M6ASITE011369		Click to Show/Hide the Full List
mod site	chr1:1534356-1534357:+		[7]
Sequence	GGGGGAGGGTGAGGCTTTGCACCCCAGCCCCTGCCCAGGCC
Motif Score	2.809946429
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000536055.5; ENST00000378755.9; ENST00000339113.8; ENST00000378756.7
External Link	RMBase: m6A_site_1810
mod ID: M6ASITE011370		Click to Show/Hide the Full List
mod site	chr1:1534490-1534491:+		[5]
Sequence	GGGGCGCCTGCCAGGGCCAGACCCAGGTGGGGCAGCCTGAA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; MM6; peripheral-blood; HEK293T; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000339113.8; ENST00000378755.9; ENST00000536055.5; ENST00000378756.7
External Link	RMBase: m6A_site_1811
mod ID: M6ASITE011371		Click to Show/Hide the Full List
mod site	chr1:1534510-1534511:+		[5]
Sequence	ACCCAGGTGGGGCAGCCTGAACCCTGCTTCCCCCTGTGGCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MM6; peripheral-blood; HEK293T; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000378756.7; ENST00000339113.8; ENST00000536055.5; ENST00000378755.9
External Link	RMBase: m6A_site_1812
mod ID: M6ASITE011372		Click to Show/Hide the Full List
mod site	chr1:1534585-1534586:+		[5]
Sequence	GAGAGAGGAGGGAGGAGGGAACCTGGCGGGGGTGTCTGAGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MM6; peripheral-blood; HEK293T; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000339113.8; ENST00000378755.9; ENST00000536055.5; ENST00000378756.7
External Link	RMBase: m6A_site_1813

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000075		Click to Show/Hide the Full List
mod site	chr1:1520575-1520576:+		[8]
Sequence	GCACCTTGTTTGGGGAAGGATTCCGTGCCTTTGTGACAGAC
Transcript ID List	ENST00000429957.1; ENST00000536055.5; ENST00000339113.8; ENST00000378755.9; ENST00000378756.7
External Link	RMBase: Pseudo_site_18

Ref 1	RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent. J Exp Clin Cancer Res. 2021 Feb 26;40(1):80. doi: 10.1186/s13046-021-01871-4.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Base-Resolution Mapping Reveals Distinct m(1)A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts. Mol Cell. 2017 Dec 7;68(5):993-1005.e9. doi: 10.1016/j.molcel.2017.10.019. Epub 2017 Nov 5.
Ref 4	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 7	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 8	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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