m6A-centered Drug Response Information

General Information of the Drug (ID: M6ADRUG0126)
Name
Perhexiline
Synonyms
Perhexilene; Perhexilina; Perhexilinum; Perhexilline; Perhexilina [INN-Spanish]; Perhexiline (INN); Perhexiline [INN:BAN]; Perhexilinum [INN-Latin]; (+)-2-(2,2-Dicyclohexylethyl)piperidine; (-)-2-(2,2-Dicyclohexylethyl)piperidine; 2-(2,2-Dicyclohexylethyl)piperidine
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Structure
3D MOL
2D MOL
Formula
C19H35N
InChI
1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2
InChIKey
CYXKNKQEMFBLER-UHFFFAOYSA-N
PubChem CID
4746
TTD Drug ID
D00SBN
DrugBank ID
DB01074
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
In total 2 item(s) under this drug
Crosstalk ID: M6ACROT05721
 Crosstalk Info 
m6A Regulator YTH domain-containing protein 1 (YTHDC1)
 Regulator Info 
m6A Target Circ_TET2
 Target Gene 
Epigenetic Regulator Circ_TET2
Regulated Target Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship m6A → ncRNA
Disease Chronic lymphocytic leukemia
 Disease Info 
Crosstalk ID: M6ACROT05724
 Crosstalk Info 
m6A Regulator RNA binding protein X (RBMX)
 Regulator Info 
m6A Target Circ_TET2
 Target Gene 
Epigenetic Regulator Circ_TET2
Regulated Target Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship m6A → ncRNA
Disease Chronic lymphocytic leukemia
 Disease Info 
References
Ref 1 Wilms' tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3Beta sequence associated with remission in one patient is detectable in other vaccinated patients. Cancer Immunol Immunother. 2012 Mar;61(3):313-22. doi: 10.1007/s00262-011-1099-y. Epub 2011 Sep 7.