m6A-centered Disease Response Information

General Information of the Disease (ID: M6ADIS0340)

Name	Diabetic foot ulcers
ICD	ICD-11: BD54

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease

In total 1 item(s) under this disease
Crosstalk ID: M6ACROT05097		Crosstalk Info
m6A Regulator	RNA demethylase ALKBH5 (ALKBH5)	Regulator Info
m6A Target	Transcription factor SOX-2 (SOX2)	Target Gene
Epigenetic Regulator	MicroRNA 155 (MIR155)
Regulated Target	Hypoxia-inducible factor 1-alpha (HIF-1-Alpha/HIF1A)
Crosstalk relationship	ncRNA → m6A

References

Ref 1	Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations. J Immunother Cancer. 2019 May 29;7(1):142. doi: 10.1186/s40425-019-0614-0.