m6A-centered Disease Response Information

General Information of the Disease (ID: M6ADIS0274)
Name
DOX-induced cardiotoxicity
ICD
ICD-11: BA00
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease
In total 1 item(s) under this disease
Crosstalk ID: M6ACROT05072
 Crosstalk Info 
m6A Regulator Fat mass and obesity-associated protein (FTO)
 Regulator Info 
m6A Target Nuclear factor erythroid 2-related factor 2 (NFE2L2)
 Target Gene 
Epigenetic Regulator Urothelial cancer associated 1 (UCA1)
Regulated Target FTO alpha-ketoglutarate dependent dioxygenase (FTO)
Crosstalk relationship ncRNA → m6A
References
Ref 1 Future pharmacological treatment options for nonexudative and exudative age-related macular degeneration. Expert Opin Emerg Drugs. 2005 Feb;10(1):119-35. doi: 10.1517/14728214.10.1.119.
Ref 2 Pharmacokinetics, Safety, and CCR2/CCR5 Antagonist Activity of Cenicriviroc in Participants With Mild or Moderate Hepatic Impairment. Clin Transl Sci. 2016 Jun;9(3):139-48. doi: 10.1111/cts.12397. Epub 2016 May 12.
Ref 3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1376).