Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT05760
[1]
m6A modification hsa-miR-143-3p hsa-miR-143-3p METTL3 Methylation : m6A sites Direct Enhancement Non-coding RNA miR-143-3p SMAD3  lncRNA       miRNA   circRNA
m6A Modification:
m6A Regulator Methyltransferase-like 3 (METTL3) WRITER
m6A Target hsa-miR-143-3p
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type Non-coding RNA (ncRNA)
Epigenetic Regulator hsa-miR-143-3p microRNA View Details
Regulated Target Mothers against decapentaplegic homolog 3 (SMAD3) View Details
Crosstalk Relationship m6A  →  ncRNA Enhancement
Crosstalk Mechanism m6A regulators directly modulate the functionality of ncRNAs through specific targeting ncRNA
Crosstalk Summary m6A-modified hsa-miR-143-3p in a METTL3 manner inhibits epithelial mesenchymal transition in bronchial epithelial cells and extracellular matrix production in lung fibroblasts by targeting Mothers against decapentaplegic homolog 3 (SMAD3).
Responsed Disease Asthma ICD-11: CA23
In-vitro Model
16HBE14o- Normal Homo sapiens CVCL_0112
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
Mothers against decapentaplegic homolog 3 (SMAD3) 3 Compound(s) Regulating the Target Click to Show/Hide the Full List
 Compound Name SIS-3 Preclinical [2]
Synonyms
SIS3 free base; Smad3 Inhibitor, SIS3; 1009104-85-1; Specific Inhibitor of Smad3; SIS3 (free base); (E)-1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one; 521985-36-4; Smad3 inhibitor SIS3; (E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one; SCHEMBL6479525; SCHEMBL6479530; CHEMBL4303604; CHEBI:87589; 1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one; ZINC34299760; NCGC00387473-03; 6,7-Dimethyl-2-((2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-prop-2-enoyl))-1,2,3,4-tetrahydroisoquinoline; HY-100444; CS-0019029; J3.550.832E; J-000258; Q27159754; (2E)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one; 2-Propen-1-one, 1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
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MOA Inhibitor
External Link
 Compound Name GNF-PF-2272 Investigative [3]
Synonyms
3-Methyltoxoflavin; MLS000528498; SMR000121073; 1,3,6-Trimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione; BAS 00444306; 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione; 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; SR-01000322764; methyltoxoflavin; CPXHNWKHOFNPDO-UHFFFAOYSA-N; 3-methyl toxoflavin; AC1LA2XZ; 32502-62-8; cid_460747; SCHEMBL2180986; CHEMBL601757; BDBM34671; CHEBI:95315; KUC104460N; HMS2304H14; STK397047; KSC-1-228; MCULE-2510138695; NCGC00093522-02; NCGC00093522-01; HY-111117
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MOA Inhibitor
External Link
 Compound Name ELLAGIC ACID Investigative [3]
Synonyms
476-66-4; Benzoaric acid; Lagistase; Eleagic acid; Alizarine Yellow; Elagostasine; 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione; Ellagic acid dihydrate; Llagic acid; Acide ellagique; Acido elagico; Acidum ellagicum; C.I. 55005; Gallogen (VAN); Gallogen (astringent); C.I. 75270; Ellagate; Ellagic acid [INN:DCF]; UNII-19YRN3ZS9P; Acido elagico [INN-Spanish]; CCRIS 774; Gallogen, astringent; Acide ellagique [INN-French]; Acidum ellagicum [INN-Latin]; MLS000069632; C14H6O8; EINECS 207-508-3; NSC407286; NSC 40728
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MOA Inhibitor
External Link
CA23: Asthma 447 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name Tezepelumab Approved [4]
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 Compound Name Procaterol Approved [5]
Synonyms
Meptin; Procaterolo; Procaterolum; Procaterol Monohydrochloride; Procaterolo [DCIT]; Procaterolum [Latin]; Meptin (TN); OPC-2009; Procaterol (INN); Procaterol [INN:BAN]; Procaterolum [INN-Latin]; (R*,S*)-(+-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone; 5-[1-hydroxy-2-(propan-2-ylamino)butyl]quinoline-2,8-diol; 8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone; 8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one
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 Compound Name GW685698X Approved [6]
Synonyms
Allermist; Avamys; Veramyst; Fluticasone furoate; GW 685698X; GW6; GW-685698; GW-685698X; Veramyst (TN); Fluticasone furoate (JAN/USAN/INN); (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl-2-furancarboxylate; 6alpha,9-Difluoro-17-(((fluoromethyl)sulfanyl)carbonyl)-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl furan-2-carboxylate
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 Compound Name Budesonide Approved [7]
Synonyms
Bidien; Budenofalk; Budeson; Budesonido; Budesonidum; Budiair; Cortivent; Entocort; Horacort; Inflammide; Micronyl; Miflonide; Preferid; Pulmaxan; Respules; Rhinocort; Spirocort; UDB; Budecort Inhaler; Budesonide Easyhaler; Budesonide MMX; Entocort EC; GionaEasyhaler; Pulmaxan turbohaler; Pulmicort Flexhaler; Pulmicort Nebuamp; Pulmicort Respules; Pulmicort Topinasal; Pulmicort turbuhaler; Rhinocort Aqua; Rhinocort Turbuhaler; Rhinocort alpha; Unit dosebudesonide; B 7777; S 1320; Budesonido [INN-Spanish]; Budesonidum [INN-Latin]; Entocort (TN); Entocort EC (TN); MAP-0010; Noex (TN); Pulmicort (TN); Rhinocort (TN); S-1320; Budesonide (JAN/USAN/INN); Budesonide [USAN:INN:BAN:JAN]; Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide; Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-,and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione; (11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione; (11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione; (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; (R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde; (RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione; (RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde; (S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione; 11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione; 16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione; 16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione; 16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione; 16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione; 16alpha-,17alpha-butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione
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 Compound Name Mometasone furoate/ formoterol fumarate Approved [8]
Synonyms
Dulera (TN)
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 Compound Name Fluprednisolone Approved [9]
Synonyms
Alphadrol
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External Link
 Compound Name Pirbuterol Approved [10]
Synonyms
Maxair; Pirbuterolum; Pyrbuterol; Pirbuterol acetate salt; CP 24315-1; Maxair (TN); Pirbuterol (INN); Pirbuterol [INN:BAN]; Pirbuterolum [INN-Latin]; CP-24315-1; CP-24,314-1; CP-24,314-14; 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-tert-butylamino ethyl)pyridine, dihydrochloride; 2-tert-Butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)ethanol; 6-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)-3-pyridinol; 6-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)pyridin-3-ol
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External Link
 Compound Name Roflumilast Approved [11]
Synonyms
162401-32-3; DAXAS; Daliresp; 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE; BY217; BYK20869; UNII-0P6C6ZOP5U; BY-217; Roflumilast (Daxas); B9302-107; 0P6C6ZOP5U; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-; CHEMBL193240; CHEBI:47657; BYK-20869; ROF; Libertek; AK110425; 3-Cyclopropylmethoxy-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide; Roflumilast [USAN]; APTA-2217; Roflumilast (JAN/USAN/INN); 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-di-chloropyrid-4-yl)benzamide; Alogliptin/roflumilast
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 Compound Name Infliximab Approved [12]
Synonyms
Remicade (TN)
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 Compound Name Formoterol/budesonide Approved [9]
Synonyms
Formoterol-budesonide mixt; Budesonide-formoterol mixt; 150693-37-1; Budesonide mixture with formoterol; Formoterol / budesonide; Symbicort Inhalation Aerosol; Budesonide/formoterol combination; Budesonide and formoterol fumarate dihydrate; DTXSID80872449; Pregna-1,4-diene-3,20-dione, 16,17-(butylidenebis(oxy))-11,21-dihydroxy-, (11beta,16alpha)-, mixt with (R*,R*)-(+-)-N-(2-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)formamide; Budesonide, Formoterol
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 Compound Name Lodoxamide Approved [9]
Synonyms
Lodoxamide ethyl; Lodoxamide trometamol; Lodoxamide tromethamine; U-42585; U-42585E; U-42718
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 Compound Name Reslizumab Approved [13]
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 Compound Name Repirinast Approved [9]
Synonyms
MY-1250; MY-5116; MY-6116
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 Compound Name Terbutaline Approved [14]
Synonyms
Asthmasian; Brethaire; Brethine; Brican; Bricanyl; Bricar; Bricaril; Bricyn; Terbutalin; Terbutalina; Terbutalino; Terbutalinum; Terbutalina [DCIT]; Terbutaline sulfate; KWD 2019; Asthmasian (TN); Brethaire (TN); Brethine (TN); Bricanyl (TN); KWD-2019; Terbutaline (INN); Terbutaline [INN:BAN]; Terbutalino [INN-Spanish]; Terbutalinum [INN-Latin]; (+-)-5-(2-((1,1-Dimethylethyl)amino)-1-hydroxyethyl)-1,3-benzenediol; (+-)-Terbutaline; 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-(9CI); 5-(2-((1,1-DIMETHYLETHYL)AMINO)-1-HYDROXYETHYL)-1,3-BENZENEDIOL; 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol; 5-{2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl}benzene-1,3-diol
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 Compound Name Ephedrine Approved [15]
Synonyms
Biophedrin; Eciphin; Efedrin; Ephedral; Ephedremal; Ephedrin; Ephedrital; Ephedrol; Ephedrosan; Ephedrotal; Ephedsol; Ephendronal; Ephoxamin; Fedrin; Kratedyn; Lexofedrin; Manadrin; Mandrin; Nasol; Racephedrine; Sanedrine; Vencipon; Zephrol; CPDD 0049; D-Ephedrine; Ephedrine (TN); Ephedrine (USP); Ephedrine [USAN:BAN]; Ephedrine l-form; I-Sedrin; L-Ephedrine; L(-)-Ephedrine; L-(+)-Ephedrine; L-(-)-Ephedrine; (+)-Ephedrin; (1R,2R)-Ephedrine; (1S,2R)-Ephedrine; (L)-EPHEDRINE; 1-EPHEDRINE; 1-Sedrin
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 Compound Name Krypton, Kr-81m Approved [9]
Synonyms
Mpi Krypton 81m Generator
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 Compound Name Ciclesonide Approved [16]
Synonyms
Alvesco; Omnair; Omnaris; Osonase; Osonide; Alvesco HFA; Ciclesonide [INN]; Omnaris HFA; RPR 251526; Alvesco (TN); BTR-15; BTR-15K; BY-9010; BYK-20426; KS-1165; Omnaris (TN); Omniair (TN); TBN-15; B-9207-015; Ciclesonide (JAN/USAN/INN); (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate
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 Compound Name Salbutamol Approved [17]
Synonyms
Aerolin; Airomir; Almotex; Anebron; Asmadil; Asmanil; Asmasal; Asmatol; Asmaven; Asmidon; Asmol; Asthalin; Asthavent; Broncovaleas; Bronter; Bugonol; Bumol; Butamol; Butohaler; Butotal; Butovent; Buventol; Cetsim; Cobutolin; Dilatamol; Ecovent; Farcolin; Gerivent; Grafalin; Libretin; Medolin; Mozal; Novosalmol; Parasma; Pneumolat; Proventil; Respax; Respolin; Rotahaler; Sabutal; Sabutamol; Salamol; Salbetol; Salbron; Salbuhexal; Salbulin; Salbupur; Salbusian; Salbutalan; Salbutamolum; Salbutan; Salbutard; Salbutine; Salbutol; Salbuven; Salbuvent; Sallbupp; Salmaplon; Salomol; Salvent; Saventol; Servitamol; Solbutamol; Spreor; Sultanol; Suprasma; Suxar; Theosal; Tobybron; Vencronyl; Ventamol; Ventilan; Ventiloboi; Ventodisks; Ventoline; Volma; Volmax; Zaperin; Albuterol Sulphate; Albuterol [USAN]; Albuterol hemisulfate; Proventil HFA; Proventil Inhaler; Salbutamol Sulphate; Salbutamol sulfate; Sultanol N; Ventalin inhaler; Ventolin Inhaler; Ventolin Rotacaps; Volare albuterol HFA; AH 3365; S 8260; Aerolin (TN); Albuterol (USP); Alti-Salbutamol; Arubendol-Salbutamol; Asmol Uni-Dose; Asthalin (TN); Broncho-Spray; Buto-Asma; Dl-Albuterol; Dl-Salbutamol; ProAi (TN); Proventil (TN); Racemic-Salbutamol; Salbu-BASF; Salbu-Fatol; Salbutamolum [INN-Latin]; Ventolin (TN); Volare easi-breathe; R,S-Albuterol; Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha-diol; Alpha-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha'-diol; DL-N-tert-Butyl-2-(4-hydroxy-3-hydroxymethylphenyl)-2-hydroxyethylamine; Alpha'-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol; Alpha(sup 1)-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol; (alpha1-((tert-butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha-diol); 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-alpha1,alpha3-diol; 2-(tert-Butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol; 2-t-Butylamino-1-(4-hydroxy-3-hydroxy-3-hydroxymethyl)phenylethanol; 4-Hydroxy-3-hydroxymethyl-alpha-((tert-butylamino)methyl)benzyl alcohol; 4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; 4-{2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
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 Compound Name Tralokinumab Approved [18]
Synonyms
CAT-354; Anti-IL 13 monoclonal antibody, CAT/AstraZeneca; IL-13 antagonist, CAT/AstraZeneca; Interleukin-13 antagonist, CAT/AstraZeneca
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 Compound Name Theobromine Approved [9]
Synonyms
83-67-0; 3,7-Dimethylxanthine; Diurobromine; Teobromin; Theostene; Theosalvose; Santheose; Thesodate; Thesal; 3,7-dimethylpurine-2,6-dione; 3,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione; Theobromin; Xanthine, 3,7-dimethyl-; 3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione; 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-; SC 15090; 2,6-Dihydroxy-3,7-dimethylpurine; Theobromine (natural); UNII-OBD445WZ5P; NSC 5039; 7-Dimethylxanthine; 2,6-Dihydroxy-3,7-dimethyl-purine; BRN 0016464; FEMA No. 3591; CCRIS 2350; HSDB 7332
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 Compound Name Colforsin daropate hci Approved [19]
Synonyms
Adehl (TN); Adele (TN)
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 Compound Name Khellin Approved [9]
Synonyms
82-02-0; Visammin; Methafrone; Amicardine; Coronin; Medekellin; Ammivisnagen; Corafurone; Amikellin; Viscardan; Benecardin; Gynokhellan; Ammipuran; Kelourin; Rykellin; Interkhellin; Interkellin; Visammimix; Khellinorm; Khellanals; Khellamine; Kalangin; Deltoside; Ammispasmin; Visnagalin; Khelangin; Kelincor; Kelicorin; Norkel; Kelamin; Simeskellina; Khelloyd; Khelfren; Visnagen; Vasokellina; Kellosal; Mefurina; Lynamine; Khelisem; Kelicor; Chellin; Amiptan; Kellin; Ammivin; Keloid; Kellina; Eskel; Cardio-khellin; Ammi-khellin; Bi-Kellina
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 Compound Name GW642444 Approved [20]
Synonyms
Fumagillinum; Fumagilline; Fumagilina; Fumidil; Fugillin; UNII-7OW73204U1; Amebacillin; Fugilin; CHEMBL32838; Fumagillin DCH; CHEBI:48635; Fumagillina [DCIT]; 7OW73204U1; Fumagillinum [INN-Latin]; Fumagilline [INN-French]; Fumagilina [INN-Spanish]; DSSTox_RID_79580; DSSTox_CID_20736; DSSTox_GSID_40736; Fumagillin [INN:BAN:DCF]; 2,4,6,8-Decatetraenedioic acid, 4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-1-oxaspiro(2,5)oct-6-yl ester
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 Compound Name Oxitropium bromide Approved [9]
Synonyms
Oxivent (TN)
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 Compound Name Arformoterol Approved [21]
Synonyms
67346-49-0; Brovana; UNII-F91H02EBWT; Arformoterol tartrate; CHEMBL1363; F91H02EBWT; CHEBI:408174; Brovana (TN); Formoterol/fluticasone propionate
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 Compound Name Ximelegatran Terminated [22]
Synonyms
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans-; y-27632; 146986-50-7; Y-27632 dihydrochloride; Y27632; UNII-0X370ROP6H; Y 27632; 0X370ROP6H; CHEBI:75393; 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide; (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE; 4-[(1R)-1-aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide; 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide; (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
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 Compound Name VR506 Approved [9]
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 Compound Name Zileuton Approved [23]
Synonyms
Leutrol; Zileutonum; Ziluton; Zyflo; Abbott brand of zileuton; Zyflo CR; Zyflo Filmtab; A 64077; Abbot 64077; Abbott 64077; A-64077; ABBOTT-64077; ABT-077; CTI-02; ZYFLO (TN); ZYFLO, Zileuton; Zileutonum [INN-Latin]; Zileuton (USP/INN); Zileuton [USAN:INN:BAN]; N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea; N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea; (+-)-1-(1-Benzo(b)thien-2-ylethyl)-1-hydroxyurea; (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea; (+/-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea; 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea; 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea
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 Compound Name Enprofylline Approved [24]
Synonyms
Enprofilina; Enprofyllinum; Nilyph; Oxeze; P 5679; D-4028; Enprofilina [INN-Spanish]; Enprofylline [USAN:INN]; Enprofyllinum [INN-Latin]; Enprofylline (USAN/INN); 3,7-Dihydro-3-propyl-1H-purine-2,6-dione; 3-Propyl-3,7-dihydro-purine-2,6-dione; 3-Propylxanthine; 3-n-Propylxanthine; 3-propyl-3,7-dihydro-1H-purine-2,6-dione; 3-propyl-7H-purine-2,6-dione
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 Compound Name Pranlukast Approved [25]
Synonyms
Azlaire; Azlaire (TN); Pranlukast (INN); N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
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 Compound Name Chymotrypsin Approved [9]
Synonyms
Alpha Chymar; Catarase; Zolyse
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 Compound Name Isoetharine Approved [26]
Synonyms
Bronkosol; Dilabron; Etyprenaline; Etyprenalinum; Isoetarin; Isoetarina; Isoetarine; Isoetarinum; Neoisuprel; Isoetharine Hcl; Win 3406; Bronkometer (TN); Bronkosol (TN); Dey-Lute Isoetharine; Isoetarina [INN-Spanish]; Isoetarine (INN); Isoetarinum [INN-Latin]; Isoetharine (USP); Isoetharine HCl S/F; Isoetharine [USAN:BAN]; 3,4-Dihydroxy-alpha-(1-(isopropylamino)propyl)benzyl alcohol; 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol
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 Compound Name Bambuterol Approved [27]
Synonyms
Bambec; Bambuterolum; Oxeol; Bambuterolum [Latin]; Terbutaline bisdimethylcarbamate; Bambec (TN); Bambuterol (INN); Bambuterol [BAN:INN]; KWD-2183; Oxeol (TN); Terbutaline bis(dimethylcarbamate); [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate; (+-)-5-(2-(tert-Butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate); 5-(2-(tert-butylamino)-1-hydroxyethyl)-3-phenylene bis(dimethylcarbamate); 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate)
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 Compound Name Doxofylline Approved [9]
Synonyms
Ansimar (TN)
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 Compound Name Dupilumab Approved [28]
Synonyms
REGN-668; REGN-668); Anti-IL-4 monoclonal antibody (asthma/atopic dermatitis), sanofi-aventis; Anti-IL-4 receptor antibody (VelocImmune, allergy/immune disorder), Regeneron/sanofi-aventis
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 Compound Name Beclomethasone Approved [29]
Synonyms
Anceron; Beclocort; Beclometason; Beclometasona; Beclometasonum; Becloval; Becodisks; Beconasol; Becotide; Inalone; Viarex; Beclometasondipropionat Mikron; Beclometasone [INN]; Vancenase AQ; B 0385; BMJ 5800; Beclometason (TN); Beclometasona [INN-Spanish]; Beclometasone (INN); Beclometasonum [INN-Latin]; Beconase (TN); Clipper (TN); Propaderm (TN); Vancenase (TN); (11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; (8R,9S,10S,11S,13R,14R,16R,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione; 9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; 9alpha-Chloro-11beta,17alpha,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione; 9alpha-Chloro-16beta-methyl-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione; 9alpha-Chloro-16beta-methylprednisolone
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 Compound Name VR632 Approved [9]
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 Compound Name Bitolterol Approved [9]
Synonyms
Tornalate
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 Compound Name Cinalukast Approved [30]
Synonyms
Cinalukast [USAN:INN]; Ro 24-5913; Cinalukast (USAN/INN); Ro-24-5913; (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid; 3'-((E)-2-(4-Cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid; 4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid; 4-[3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]anilino]-2,2-diethyl-4-oxobutanoic acid
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 Compound Name Cromoglicate Approved [31]
Synonyms
Crolom (TN); Intal (TN); Nasalcrom (TN); Opticrom (TN); Optrex Allergy (TN); Prevalin (TN); Rynacrom (TN)
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 Compound Name Zafirlukast Approved [32]
Synonyms
Accolate; Accoleit; Aeronix; Olmoran; Respix; Zafirst; AstraZeneca brand of zafirlukast; Menarini brand of zafirlukast; Novartis brand of zafirlukast; Zeneca brand of zafirkulast; Accolate (TN); Accoleit (TN); Vanticon (TN); Zafirlukast [USAN:BAN:INN]; Accolate, Accoleit, Vanticon, Zafirlukast; Zafirlukast (JAN/USAN/INN); Cyclopentyl N-[3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methylindol-5-yl]carbamate; Cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate; Cyclopentyl 3-[2-methoxy-4-(2-methylphenylsulfonylcarbamoyl)benzyl]-1-methyl-1H-indol-5-ylcarbamate; Cyclopentyl [3-(2-methoxy-4-{[(2-methylphenyl)sulfonyl]carbamoyl}benzyl)-1-methyl-1H-indol-5-yl]carbamate; Cyclopentyl (1-methyl-3-{[2-(methyloxy)-4-({[(2-methylphenyl)sulfonyl]amino}carbonyl)phenyl]methyl}-1H-indol-5-yl)carbamate; Carbamic acid, (3-((2-methoxy-4-((((2-methylphenyl)sulfonyl)amino)carbonyl)phenyl)methyl)-1-methyl-1H-indol-5-yl)-, cyclopentyl ester; 4-(5-cyclopentyloxy-carbonylamino-1-methyl-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide; 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide; 4-(5-cyclopentyloxycarbonylamino-2-methylindol-3-yl-methyl)-3-methoxy-N-O-tolylsulfonylbenzamide
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 Compound Name Brodalumab Approved [33]
Synonyms
AMG 827
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 Compound Name Fenoterol Approved [34]
Synonyms
Berotec; Berotek; Fenoterolum; Phenoterol; TH 1165A; Berotec (TN); Fenoterolum [INN-Latin]; P-Hydroxyphenylorciprenaline; Th-1165a; Fenoterol (USAN/INN); Fenoterol [USAN:BAN:INN]; P-Hydroxyphenyl-orciprenaline; 1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane; 1-(p-Hydroxyphenyl)-2-((beta-hydroxy-beta-(3',5'-dihydroxyphenyl))ethyl)aminopropane; 3,5-Dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyl alcohol; 5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol; 5-(1-hydroxy-2-{[2-(4-hydroxyphenyl)-1-methylethyl]amino}ethyl)benzene-1,3-diol; 5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-1,3-diol; 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol
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 Compound Name Methacholine Chloride Approved [35]
Synonyms
Methacholine; Acetylmethylcholine; Methacholin; Mecholine; Mecholin; Provocholine; Methacholinum; beta-Methylacetylcholine; 55-92-5; Choline, acetyl-beta-methyl-; Acetyl-beta-methylcholine; BRN 1769932; CHEBI:6804; 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-; AMMONIUM, (2-HYDROXYPROPYL)TRIMETHYL-, ACETATE (ESTER); 2-acetyloxypropyl(trimethyl)azanium; C8H18NO2; AC1Q5XYD; AC1L1COQ; Prestwick2_000759; Prestwick0_000759; Prestwick3_000759; Prestwick1_000759; CHEMBL978; 2-(acetyloxy)-n,n,n-trimethylpropan-1-aminium
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 Compound Name Formoterol Approved [36]
Synonyms
Foradile; Formoterol tartrate; Oxeze Turbuhaler Foradil; MOLI000351; Atimos (TN); Atock (TN); Foradil (TN); Foradile (TN); Formoterol (INN); Modulite (TN); Oxeze (TN); Oxis (TN); Perforomist (TN); Formoterol, ((R*,R*)-(+-)-)-isomer; N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide; N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide; N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide; (+-)-2'-Hydroxy-5'-((RS)-1-hydroxy-2-(((RS)-p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide; 3-formylamino-4-hydroxy-alpha-(N-1-methyl-2-p-methoxyphenethylaminomethyl)benzyl alcohol.hemifumarate
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 Compound Name Aminophylline Approved [37]
Synonyms
Aminocardol; Aminodur; Aminofilina; Aminofillina; Aminophyllin; Ammophyllin; Cardiofilina; Cardiomin; Cardophylin; Cardophyllin; Carena; Cariomin; DOBO; Diaphilline; Diaphyllin; Diaphylline; Diophllin; Diophyllin; Diuxanthine; Ethophylline; Eufilina; Euphyllin; Euphylline; Euphyllinum; Eurphyllin; Euufilin; Euufillin; Genophyllin; Grifomin; Inophylline; Lasodex; Linampheta; Lixaminol; Metaphyllin; Metaphylline; Minaphil; Miofilin; Neophyiline; Norofilina; Peterphyllin; Phylcardin; Phyllindon; Phyllocontin; Phyllotemp; Somophyllin; Stenovasan; Syntophyllin; Theodrox; Theolamine; Theolone; Theomin; Theophyldine; Thephyldine; Truphylline; Vasofilina; A 1755; BY 108; Minomal(TN); Phyllocontin (TN); TH/100; Truphylline (TN)
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 Compound Name Rimiterol Approved [9]
Synonyms
Rimiterol Hydrobromide; EINECS 250-834-6; WG-253; 31842-61-2; R 798; (R*,S*)-4-(Hydroxypiperidin-2-ylmethyl)pyrocatechol hydrobromide; erythro-alpha-(3,4-Dihydroxyphenyl)-2-piperidinemethanol hydrobromide; 4-[(S)-hydroxy-[(2R)-piperidin-2-yl]methyl]benzene-1,2-diol hydrobromide; 2-Piperidinemethanol, alpha-(3,4-dihydroxyphenyl)-, (R*,S*)-, hydrobromide; API0025612; UNII-I29DRR8S3R component QPYZEEKXUYXZBK-PKKHVXKMSA-N; 1,2-Benzenediol, 4-(hydroxy-2-piperidinylmethyl)-, hydrobromide, (R*,S*)- (9CI)
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 Compound Name Mepolizumab Approved [38]
Synonyms
Bosatria; Scoparianoside C; SB 240563; Immunoglobulin G1, anti-(human interleukin 5) (human-mouse monoclonal SB-240563 gamma1-chain), disulfide with human-mouse monoclonal SB-240563 kappa-chain, dimer; (2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxane-2-carboxylic acid
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 Compound Name CNTO-1959 Phase 3 [39]
Synonyms
Guselkumab
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 Compound Name Indacaterol Approved [40]
Synonyms
312753-06-3; QAB149; Arcapta; Onbrez; QAB-149; QAB 149; UNII-8OR09251MQ; 753498-25-8; CHEMBL1095777; CHEBI:68575; 8OR09251MQ; (R)-5-(2-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one; 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one; Indacaterol Maleic Acid Salt; Indacaterol (USAN/INN); Indacaterol [USAN:INN:BAN]; 5-{(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl}-8-hydroxyquinolin-2(1H)-one; 5-(2-(5,6-Diethylindan-2-ylamino)-1-hydroxyethyl)-8-hydroxy-1H-quinolin-2-one; Indacaterol/mometasone
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 Compound Name Levalbuterol Approved [9]
Synonyms
Levosalbutamol; 34391-04-3; (R)-salbutamol; Xopenex; R-Salbutamol; R-Albuterol; (r)-(-)-salbutamol; UNII-EDN2NBH5SS; 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; EDN2NBH5SS; CHEBI:8746; Levosalbutamol (INN); Levosalbutamol [INN]; (R)-albuterol; m-Xylene-alpha,alpha'-diol, alpha(sup 1)-((tert-butylamino)methyl)-4-hydroxy-, (R)-(-)-; (-)-alpha(sup 1)-(((1,1-Dimethylethyl)amino)methyl)-4-hydroxy-1,3-benzenedimethanol
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 Compound Name Metaproterenol Sulfate Approved [41]
Synonyms
Metaproterenol; ORCIPRENALINE; Alupent; 586-06-1; Orciprenalinum; Orciprenalina; Orciprenalinum [INN-Latin]; Orciprenalina [INN-Spanish]; Metaproterenol polistirex; Metaprel; Alotec; Prometa; Orciprenaline [INN]; CCRIS 9017; Orciprenaline (INN); EINECS 209-569-1; CHEMBL776; BRN 2807247; (RS)-1-(3,5-Dihydroxyphenyl)-2-isopropylaminoethanol; CHEBI:6792; 3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol; 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol
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 Compound Name Ritlecitinib Approved [42]
Synonyms
CBRJPFGIXUFMTM-WDEREUQCSA-N; 1792180-81-4; UNII-2OYE00PC25; 2OYE00PC25; PF06651600; 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one; GTPL9559; SCHEMBL16764638; BCP24778; EX-A2613; ZINC526061581; example 5 [WO2015083028]; ACN-040697; compound 11 [PMID: 28139931]; HY-100754; CS-0020243; 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malonate; 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
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 Compound Name Dyphylline Approved [43]
Synonyms
Aristophyllin; Asthmolysin; Astmamasit; Astrophyllin; Circain; Circair; Coronal; Coronarin; Corphyllin; Dihydroxypropyltheophylline; Diprofilina; Diprofillin; Diprofillina; Diprofilline; Diprophyllin; Diprophylline; Diprophyllinum; Dipropylline; Droxine; Dyflex; Glyfyllin; Glyphyllin; Glyphylline; Glyphyllinum; Hidroxiteofillina; Hiphyllin; Hyphylline; Iphyllin; Isophyllen; Liactemin; Lufyllin; Neophyl; Neophyllin; Neophylline; Neostenovasan; Neothylline; Neotilina; Neufil; Neutrafil; Neutrafillina; Neutraphyllin; Neutraphylline; Neutroxantina; Propyphyllin; Protheophylline; Purifilin; Silbephyllin; Silbephylline; Solufilin; Solufyllin; Soluphyllin; Synthophylline; Tefilan; Teofen; Tesfen; Theal; Thefylan; Dihydroxypropyl theophylline; Dihydroxypropyl theopylin; Dilor G; Diprofillina [DCIT]; Dyphylline [USAN]; Neophyllin M; Theal ampules; AFI-Phyllin; COR-theophylline; Dihydroxypropyl theopylin (german); Dilor-400; Diphyllin (VAN); Diprofilina [INN-Spanish]; Diprophyllinum [INN-Latin]; Dyphylline (USP); Lufyllin (TN); Neo-Vasophylline; Diprophylline (JAN/INN); Neothylline, Lufyllin, diprophylline,Dyphylline; (+-)-7-(2,3-Dihydroxypropyl)theophylline; (+-)-diprophylline; (+-)-dyphylline; (1,2-Dihydroxy-3-propyl)thiophyllin; 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine; 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl; 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine; 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 7-(2,3-Dihydroxypropyl)theophylline; 7-(2,3-Dioxypropyl)theophylline; 7-(2,3-dihydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione; 7-(beta,gamma-Dihydroxypropyl)theophylline; 7-(beta.,.gamma.-Dihydroxypropyl)theophylline; 7-DIHYDROXYPROPYLTHEOPHYLLINE; 7-[2,3-Dihydroxypropyl]-theophylline
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 Compound Name Hydriodic acid iodine-125 Approved [9]
Synonyms
Hydriodic acid; Iodine-125
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 Compound Name Benralizumab Approved [44]
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 Compound Name Omalizumab Approved [45]
Synonyms
Xolair; Omalizumab (genetical recombination); Xolair (TN); Omalizumab (USAN/INN); Omalizumab (genetical recombination) (JAN)
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 Compound Name Protokylol Hydrochloride Approved [9]
Synonyms
Ventaire
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 Compound Name Iodinated glycerol Approved [9]
Synonyms
Organidin; Iodopropylidene glycerol; Glycerol, Iodinated; 5634-39-9; C6H11IO3; CCRIS 2378; 2-(1-IODOETHYL)-1,3-DIOXOLANE-4-METHANOL; HSDB 4185; Glycerol, iodinated [USAN:BAN]; NCI-C55469; EINECS 227-079-6; 1,3-Dioxolane-4-methanol, 2-(1-iodoethyl)-; 2-(1-Iodoethyl)-1,3-dioxolan-4-ylmethanol; [2-(1-iodoethyl)-1,3-dioxolan-4-yl]methanol; Iodinated Glycerol B; 1,3-Dioxolane-4-methanol, 2-(iodoethyl)-; Glycyrrhiza; (2-(1-Iodoethyl)-1,3-dioxolan-4-yl)methanol; iodoglycerin; Glycerol, Iondinated; SCHEMBL19693
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 Compound Name VR315 Approved [9]
External Link
 Compound Name Montelukast Approved [46]
Synonyms
Brondilat; Montair; Singular; Apxi toxin; MK 0476; Brondilat (TN); MK-0476; Montelukast (INN); Montelukast [INN:BAN]; Singulair (TN); Sodium 1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropylacetate; {1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid; (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid; 1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid; 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
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 Compound Name RELVARTM or BREOTM ELLIPTATM NDA filed [47]
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 Compound Name A378 IND submitted [48]
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 Compound Name Depemokimab Phase 3 [49]
Synonyms
GSK3511294
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 Compound Name GSK3511294 Phase 3 [50]
Synonyms
depemokimab
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 Compound Name Fevipiprant Phase 3 [51]
Synonyms
872365-14-5; NVP-QAW039; QAW039; UNII-2PEX5N7DQ4; 2PEX5N7DQ4; 2-[2-methyl-1-[[4-methylsulfonyl-2-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid; 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid; 2-Methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridine-3-acetic acid; Fevipiprant [INN]; Fevipiprant [USAN:INN]; QAW 039; Fevipiprant (JAN/USAN/INN); GTPL8995; SCHEMBL1940595; CHEMBL3137332; QAW-039; HMS3743E19; BCP25015; EX-A2495; BDBM50233520; ZINC43101772; AB85348; CS-5956; DB12011; SB16897; (1-(4-((Methane)sulfonyl)-2-trifluoromethylbenzyl)-2-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)acetic acid; 2-(1-((4-Methanesulfonyl-2-(trifluoromethyl)phenyl)methyl(-2-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)acetic acid; AC-31956; AS-74870; HY-16768; DS-022511; FT-0774596; D10631; Q27077292; 1-(4-methanesulfonylbenzyl)-2-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)acetic acid; (2-methyl-1-{[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl}-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid; [1-(4-Methanesulfonyl-2-trifluoromethyl-benzyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid; [2-METHYL-1-[4-(METHYLSULFONYL)-2-(TRIFLUOROMETHYL)BENZYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]ACETIC ACID; 2-(1-{[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid; 2-[2-methyl-1-[[4-methylsulfonyl-2-(trifluoromethyl)phenyl]methyl]pyrrolo[5,4-b]pyridin-3-yl]acetic acid; FSY
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 Compound Name CBP-201 Phase 3 [52]
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 Compound Name Astegolimab Phase 3 [53]
Synonyms
MSTT1041A; RG6149
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 Compound Name SAR440340 Phase 3 [54]
Synonyms
Itepekimab
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 Compound Name D-5519 Phase 3 [55]
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 Compound Name Setipiprant Phase 3 [56]
Synonyms
ACT-129968
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 Compound Name Lebrikizumab Phase 3 [57]
Synonyms
RG3637
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 Compound Name SAR231893 Phase 3 [58]
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 Compound Name GMI-1070 Phase 3 [59]
Synonyms
GMI-1010; GMI-1011; GMI-1040 series; GMI-1077; Glyosin, GlycoMimetics; Heterobifunctional glycomimetic pan-selectin inhibitors (smallmolecule therapeutic), GlycoMimetics; Selectin inhibitors (asthma/sickle cell anemia/hematological neoplasm), GlycoMimetics
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 Compound Name Pumactant Phase 3 [60]
Synonyms
Zofac; AP-0016; Pumactant, Britannia; Pumactant, airPharma; Pumactant, Britannia/airPharma
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 Compound Name AMG 386 Phase 3 [61]
Synonyms
7440-23-5; Natrium; Sodium-23; Sodio; Sodium metal; Sodio [Spanish]; Sodium (liquid alloy); UNII-9NEZ333N27; HSDB 687; EINECS 231-132-9; UN1428; UNII-23J3BHR95O; Sodium, dry stick; 9NEZ333N27; MFCD00085307; Sodium, 998%, oiled sticks, wrapped in aluminium foil; monosodium; sodium atom; mono sodium; mono-sodium; Sodium, CP; SodiuR4733m hydride, CP; AC1NSENP; ACMC-1BKTZ; Sodium, ACS reagent, dry; 11Na; EC 231-132-9; AC1Q1W6R; SODIUM, LARGE PIECES; Sodium hydride, dry, 95%; NAH 80; HSDB 745; CTK2H7876; CHEBI:26708; Oravescent fentanyl; R3487; PT-15; R4930
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External Link
 Compound Name Vinanterol/fluticasone furoate Phase 3 [62]
Synonyms
Relovair (TN)
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External Link
 Compound Name ISRAPAFANT Phase 3 [63]
Synonyms
Y-24180; Pafnol (Mitsubishi Pharma, JP); Rac-4-(2-Chlorophenyl)-2-[2-(4-isobutylphenyl)ethyl]-6,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
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External Link
 Compound Name Quinotolast Phase 3 [64]
Synonyms
Aslock; Quinotalast; FK-021; FR-71021
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External Link
 Compound Name E004 Phase 3 [65]
External Link
 Compound Name ABT-761 Phase 3 [66]
Synonyms
Atreleuton; Atreleuton [USAN]; ABT 761; A-85761; Atreleuton (USAN/INN); 1-[(2R)-4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea
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External Link
 Compound Name Ciclesonide Approved [67]
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 Compound Name QAW-039 Phase 3 [68]
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 Compound Name SOTB07 Phase 3 [69]
External Link
 Compound Name MDI-P Phase 3 [70]
Synonyms
CHEMBL595840; 60986-80-3; 5-methyl-3,6-diphenylisoxazolo[4,5-c]pyridin-4(5H)-one; 3,6-Diphenyl-5-methylisoxazolo[4,5-c]pyridin-4(5H)-one; 3,6-DIPHENYL-5-METHYLISOXAZOLO(4,5-C)PYRIDIN-4(5H)-ONE; AC1Q3XQS; AC1Q3XQT; AC1N5X7T; MLS002153017; SCHEMBL3663640; GTPL6218; CTK5B2529; cid_4250909; DTXSID10401226; LCNDUGHNYMJGIW-UHFFFAOYSA-N; HMS2206G07; 5-methyl-3,6-diphenyl-isoxazolo[4,5-c]pyridine-4(5H)-one; ZINC394853; HMS3358C19; BDBM50305859; AKOS024323421; MCULE-8467817198; SMR001229079; FT-0714059
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External Link
 Compound Name VR647 Phase 3 [71]
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 Compound Name Fluticasone furoate/ fluticasone propionate Phase 3 [72]
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 Compound Name Bavituximab Phase 2 [73]
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 Compound Name Darbufelone Phase 2/3 [74]
Synonyms
PD-136095
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External Link
 Compound Name CEP1347 Phase 2/3 [75]
Synonyms
AC1L31ZX; SCHEMBL1649555; ZINC103589452; DB05403
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External Link
 Compound Name Aerovant Phase 2a [76]
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 Compound Name Bimosiamose Phase 2a [76]
Synonyms
TBC 1269; TBC-1269
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External Link
 Compound Name AZD1402 Phase 2 [77]
Synonyms
Elarekibep
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External Link
 Compound Name CSJ117 Phase 2 [78]
Synonyms
Ecleralimab
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External Link
 Compound Name AZD8154 Phase 2 [79]
Synonyms
1H-Isoindol-1-one, 2-((1S)-1-cyclopropylethyl)-2,3-dihydro-5-(4-methyl-2-((6-(2-oxo-1-pyrrolidinyl)-2-pyridinyl)amino)-5-thiazolyl)-7-(methylsulfonyl)-; 2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxopyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3H-isoindol-1-one; 2215022-45-8; AKOS040757410; Azd 8154; AZD 8154 [WHO-DD]; AZD8154; AZD-8154; AZD-8154 [WHO-DD]; BDBM50512861; CHEMBL4558527; CS-0371158; EX-A5133; Example 1 [WO2018055040A1]; GTPL11204; HY-115870; J5M3TCK9Y9; MS-30088; SCHEMBL22204109; UNII-J5M3TCK9Y9
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External Link
 Compound Name Amlitelimab Phase 2 [80]
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 Compound Name RG6341 Phase 1 [81]
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 Compound Name GB001 Phase 2 [82]
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 Compound Name SelK2 Phase 2 [83]
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 Compound Name GSK3772847 Phase 2 [84]
External Link
 Compound Name AVTX-002 Phase 2 [85]
Synonyms
quisovalimab
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External Link
 Compound Name RPT193 Phase 2 [86]
Synonyms
(1R,3r)-3-((R)-3-(1-(5-Chloro-4-(((R)-1-(2,4-dichlorophenyl)ethyl)amino)-6-methylpyrimidin-2-yl)azetidin-3-yl)piperidin-1-yl)-1-methylcyclobutane-1-carboxylic acid; 2366152-15-8; 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methylpyrimidin-2-yl]azetidin-3-yl]piperidin-1-yl]-1-methylcyclobutane-1-carboxylic acid; CS-0610200; Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans-; example 37 [WO2019147862A1]; GLXC-26793; GTPL12893; HY-148074; MS-30263; Q0M1LOC2MM; RPT193; RPT193; RPT-193; SCHEMBL21193871; SCHEMBL21207415; Zelnecirnon; Zelnecirnon; zelnecirnon [INN]
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External Link
 Compound Name MTPS9579A Phase 2 [87]
Synonyms
RG6173
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External Link
 Compound Name TD-8236 Phase 2 [88]
External Link
 Compound Name AMG 853 Phase 2 [89]
Synonyms
VIDUPIPRANT; 1169483-24-2; AMG-853; UNII-61OTZ32XNC; 61OTZ32XNC; 2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-cyclopropylphenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetic acid; CHEMBL1951575; AMG 853(AMG853;Vidupiprant); Benzeneacetic acid, 5-chloro-4-[2-[[(2-chloro-4-cyclopropylphenyl)sulfonyl]amino]-4-[[(1,1-dimethylethyl)amino]carbonyl]phenoxy]-2-fluoro-; Vidupiprant [USAN:INN]; AMG853;Vidupiprant; Vidupiprant (USAN/INN); AMG853; SCHEMBL4344221; GTPL10169; DTXSID40151606; BCP28132; ZINC43206238
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External Link
 Compound Name Iralukast Phase 2 [90]
Synonyms
CGP-45715A
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External Link
 Compound Name PL-3994 Phase 2 [91]
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 Compound Name QBX258 Phase 2 [92]
External Link
 Compound Name Revamilast Phase 2 [93]
Synonyms
GRC-4039; PDE 4 inhibitor (inflammation), Glenmark; Phosphodiesterase 4 inhibitor (inflammation), Glenmark; Revamilast (inflammation), Glenmark
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External Link
 Compound Name BI-54903 Phase 2 [94]
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 Compound Name BI-54903 + olodaterol Phase 2 [95]
External Link
 Compound Name CROMOGLYCATE LISETIL HYDROCHLORIDE Phase 2 [96]
Synonyms
Diethyl L-lysylcromoglycate dihydrochloride; KY-556; N-556
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External Link
 Compound Name PF-06700841 Phase 2 [42]
Synonyms
BUWBRTXGQRBBHG-RUXDESIVSA-N; 2140301-96-6; PF-06700841 free base; EX-A2762; 1883299-62-4; ((S)-2,2-difluorocyclopropyl)(3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone
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External Link
 Compound Name ONO-6950 Phase 2 [97]
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 Compound Name GSK679586 Phase 2 [98]
External Link
 Compound Name PIRODOMAST Phase 2 [99]
Synonyms
Sch-37224; 1-(4-Hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridin-3-yl)pyrrolidine; 1-(4-Hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridin-3-yl)pyrrolidinium hydroxide inner salt; 4-Hydroxy-1-phenyl-3-(1-pyrrolidinyl)-1,8-naphthyridin-2(1H)-one
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 Compound Name AP-761 Phase 2 [100]
Synonyms
BI-671800
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 Compound Name OX-914 Phase 2 [101]
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 Compound Name HI-1640V Phase 2 [102]
External Link
 Compound Name PNU-142731A Phase 2 [103]
Synonyms
9-[2-Oxo-2-(pyrrolidin-1-yl)ethyl]-2,4-bis(pyrrolidin-1-yl)-9H-pyrimido[4,5-b]indole hydrochloride
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External Link
 Compound Name Tipelukast Phase 2 [104]
Synonyms
Asthma therapy, MediciNova; KCA-757; MN-001
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External Link
 Compound Name BIO-1211 Phase 2 [105]
Synonyms
BIO 1211; 187735-94-0; UNII-61G4E2353I; CHEMBL88478; 61G4E2353I; BIO1211; GTPL6589; SCHEMBL1223367; MolPort-023-276-985; ZINC3930111; BDBM50074661; AKOS024457866; L-Proline, N-(2-(4-((((2-methylphenyl)amino)carbonyl)amino)phenyl)acetyl)-L-leucyl-L-alpha-aspartyl-L-valyl-; L-Proline, N-((4-((((2-methylphenyl)amino)carbonyl)amino)phenyl)acetyl)-L-leucyl-L-alpha-aspartyl-L-valyl-
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External Link
 Compound Name LM-1507.NA Phase 2 [106]
Synonyms
MEN-91507; (E)-8-[2-[4-[4-(4-Fluorophenyl)butoxy]phenyl]vinyl]-2-(1H-tetrazol-5-yl)-4H-benzopyran-4-one sodium salt
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 Compound Name Altrakincept Phase 2 [107]
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 Compound Name BT-061 Phase 2 [108]
External Link
 Compound Name Pascolizumab Phase 2 [109]
Synonyms
SB-240683; Interleukin-4 antibody, SmithKline Beecham; Anti-IL-4 antibody (humanized), PDL; Anti-IL-4 antibody (humanized), Protein Design Labs
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 Compound Name RNS-60 Phase 2 [110]
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 Compound Name MK-1029 Phase 2 [111]
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 Compound Name ABT-308 Phase 1 [112]
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 Compound Name GW-870086-X Phase 2 [113]
Synonyms
Glucocorticoid agonist (asthma), GlaxoSmithKline; GW-870086-X (inhaled, asthma), GlaxoSmithKline
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External Link
 Compound Name Montelukast/mometasone Phase 2 [114]
Synonyms
MK-0476C
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External Link
 Compound Name JNJ-39758979 Phase 2 [115]
External Link
 Compound Name Oglemilast Phase 2 [116]
Synonyms
GRC-3886; Oglemilast (oral, COPD/asthma), Glenmark
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 Compound Name AZD-3199 Phase 2 [117]
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 Compound Name PF-4191834 Phase 2 [118]
Synonyms
PF-04191834
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External Link
 Compound Name TA-270 Phase 2 [119]
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 Compound Name E-6700 Phase 2 [120]
External Link
 Compound Name IPL-512602 Phase 2 [121]
Synonyms
BLX-LSAID; IPL-576 series; OX-LSAID; Lead LSAID (asthma), Biolipox; Lead LSAID (asthma), Orexo; Lead LSAID (asthma), Inflazyme/Aventis; Lead LSAID (asthma), Inflazyme/sanofi-aventis
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External Link
 Compound Name BAY-X-7195 Phase 2 [122]
Synonyms
UGWPB2QIT9; UNII-UGWPB2QIT9; BAY X-7195; BAY X 7195; AC1O5X0Q; 143538-27-6; SCHEMBL156423; CHEMBL314115; 4-[(Z,4S)-7-hydroxy-7-oxo-1-[4-(4-phenoxybutoxy)phenyl]hept-2-en-4-yl]sulfanylbenzoic acid
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 Compound Name Anti-IL-5 Receptor mab Phase 2 [123]
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 Compound Name TC-6987 Phase 2 [124]
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 Compound Name MEDI-528 Phase 2 [125]
External Link
 Compound Name KB-003 Phase 2 [126]
Synonyms
KB-002; Anti-GM-CSF mAb (autoimmune disease), Ludwig/KaloBios; Anti-GM-CSF mAb (inflammatory disease/rheumatoid arthritis/asthma), KaloBios
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 Compound Name JNJ-40929837 Phase 2 [127]
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 Compound Name AZD-5069 Phase 2 [128]
Synonyms
CXCR2 inhibitor (COPD), Astrazeneca
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 Compound Name TJ-9 Phase 2 [129]
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 Compound Name VALERGEN-BT Phase 2 [130]
Synonyms
Blomia tropicalis allergen immunotherapy (sublingual, asthma), National Biopreparations Center
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External Link
 Compound Name AIM-102 Phase 2 [131]
External Link
 Compound Name Rambazole Phase 2 [132]
Synonyms
Talarozole; 201410-53-9; R-115866; N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzo[d]thiazol-2-amine; R115866; CHEMBL459505; C21H23N5S; Rambazole (TN); Talarozole (USAN/INN); Talarozole [USAN:INN]; R 115866; N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)-2-benzothiazolamine; Talarozole pound> SCHEMBL721201; CHEBI:102167; MolPort-018-666-712; SNFYYXUGUBUECJ-UHFFFAOYSA-N; BCP28256; BCP21218; BDBM50253810; 0328AB; AKOS005067289; DB13083; CS-1343; NCGC00378894-01; HY-14531; AX8224298; D09385; W-5674; MEN13510
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External Link
 Compound Name WY-50295-tromethamine Phase 2 [133]
Synonyms
WY-50295T; Wy-49232
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External Link
 Compound Name RV-568 Phase 2 [134]
External Link
 Compound Name N6022 Phase 2 [135]
Synonyms
1208315-24-5; N-6022; UNII-80LIU5P95D; 80LIU5P95D; CHEMBL1738699; 3-(5-(4-(1H-Imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid; 3-{1-(4-Carbamoyl-2-Methylphenyl)-5-[4-(1h-Imidazol-1-Yl)phenyl]-1h-Pyrrol-2-Yl}propanoic Acid; N 6022; YVPGZQLRPAGKLA-UHFFFAOYSA-N; 3-[1-(4-carbamoyl-2-methylphenyl)-5-[4-(1H-imidazol-1-yl)phenyl]-1H-pyrrol-2-yl]propanoic acid; SCHEMBL244480; EX-A343; MolPort-035-789-691; HMS3653J15; BCP09367; s7589; ZINC66156654; BDBM50354475; 2573AH; AKOS030526322; DB12206
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 Compound Name AZX-100 Phase 2 [136]
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 Compound Name CYT003 Phase 2 [137]
External Link
 Compound Name Ontazolast Phase 2 [138]
Synonyms
UNII-8P8TW6B25I; BIRM-270; 147432-77-7; 8P8TW6B25I; N-[(1S)-2-cyclohexyl-1-pyridin-2-ylethyl]-5-methyl-1,3-benzoxazol-2-amine; Ontazolast [USAN:INN]; AC1Q4WID; Ontazolast (USAN/INN); SCHEMBL75875; AC1L2G78; CHEMBL2104845; 2-(((S)-2-Cyclohexyl-1-(2-pyridyl)ethyl)amino)-5-methylbenzoxazole; n-[(1s)-2-cyclohexyl-1-(2-pyridinyl)ethyl]-5-methyl-2-benzoxazolamine; D02847; 32254-EP2311827A1; 32254-EP2301933A1; 32254-EP2281815A1; 32254-EP2305640A2; 2-Benzoxazolamine, N-(2-cyclohexyl-1-(2-pyridinyl)ethyl)-5-methyl-, (S)-
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 Compound Name ASM-024 Phase 2 [139]
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 Compound Name PRO-98498 Phase 2 [140]
Synonyms
HAE-1; Asthma therapy (subcutaneous), Genentech
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 Compound Name KP-496 Phase 2 [141]
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 Compound Name GSK2269557 Phase 2 [142]
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 Compound Name THR-18 Phase 2 [143]
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 Compound Name LEO 124249 Phase 2 [42]
Synonyms
delgocitinib; UNII-9L0Q8KK220; JTE-052; 9L0Q8KK220; 1263774-59-9; Delgocitinib [USAN]; Delgocitinib (JAN/USAN); JTE052; JTE-052A; GTPL9619; SCHEMBL12547007; LEO 124249A; HY-109053; CS-0031558; D11046; 1,6-Diazaspiro(3.4)octane-1-propanenitrile, 3-methyl-beta-oxo-6-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-, (3S,4R)-; 3-((3S,4R)-3-methyl-6-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1,6-diazaspiro(3.4)octan-1-yl)-3-oxopropanenitrile
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External Link
 Compound Name GW274150 Phase 2 [144]
Synonyms
GW-274150; UNII-0ZZF1V8G63; 0ZZF1V8G63; CHEMBL114551; SCHEMBL120693; L-Homocysteine, S-(2-((1-iminoethyl)amino)ethyl)-; GTPL9849; ZINC2004483; BDBM50086467; AKOS030526714; DB12237; CS-5419; HY-12119; GW-274150;GW 274150; [2-[(1-iminoethyl) amino]ethyl]-L-homocysteine; (S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-butyric acid; (2S)-2-amino-4-[2-(1-aminoethylideneamino)ethylsulfanyl]butanoic acid
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External Link
 Compound Name Masilukast Phase 2 [145]
Synonyms
D-3523; MCC-847; ZD-3523
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External Link
 Compound Name R411 Phase 2 [146]
External Link
 Compound Name Tepoxalin Phase 2 [147]
Synonyms
103475-41-8; Orf-20485; ORF 20485; Tepoxaline; Tepoxalina; Tepoxalinum [Latin]; Tepoxaline [French]; Tepoxalina [Spanish]; RWJ 20485; Tepoxalin [USAN:INN]; 5-(4-Chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide; UNII-TZ4OX61974; C20H20ClN3O3; 1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-; CHEMBL316040; CHEBI:76277; TZ4OX61974; 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid; RWJ-20485; SIL-4R
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 Compound Name BI-144807 Phase 2 [148]
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 Compound Name GSK2245035 Phase 2 [149]
Synonyms
GSK-2245035
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 Compound Name AMG 157 Phase 2 [150]
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 Compound Name Anti-M1 prime Phase 2 [151]
External Link
 Compound Name ONO-AE1-437 Phase 2 [152]
Synonyms
16-[3-(Methoxymethyl)phenyl]-5-thia-17,18,19,20-tetranorprostaglandin E1
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External Link
 Compound Name VALERGEN-DP Phase 2 [153]
Synonyms
Dermatophagoides pteronyssinus allergen immunotherapy (subcutaneous, asthma), National Biopreparations Center
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External Link
 Compound Name AHCQ Phase 2 [154]
External Link
 Compound Name Anrukinzumab Phase 2 [155]
Synonyms
Ab13-2; IMA-638; PF-05230917; Anti-IL-13 antibody (asthma), Wyeth; Anti-IL-13 antibody (ulcerative colitis), Pfizer
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 Compound Name WIN-901 Phase 2 [156]
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 Compound Name Noberastine Phase 2 [157]
Synonyms
Flamizole; R-64947; R-72075
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 Compound Name TPI ASM8 Phase 2 [158]
External Link
 Compound Name SB-265610 Phase 2 [159]
Synonyms
SB 265610; 211096-49-0; CHEMBL38182; UNII-9P785F0579; N-(2-BROMOPHENYL)-N'-(7-CYANO-1H-BENZOTRIAZOL-4-YL)UREA; 9P785F0579; 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea; sb265610; SCHEMBL1535925; CTK8E9340; DTXSID10175339; MolPort-019-939-274; MolPort-044-561-465; ZINC603064; BCP28242; BDBM50102222; AKOS024457259; NCGC00242491-01; NCGC00242491-02; KB-80496; RT-015648; SB265610, > J-013849; 1-(2-Bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl)-urea; Urea, N-(2-bromophenyl)-N'-(4-cyano-1H-be
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External Link
 Compound Name ZY-15106 Phase 2 [160]
Synonyms
MgNAAGA; NAAGAMg; Rhinaaxia; N-Acetylaspartyl-glutamic acid magnesium salt
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 Compound Name PF-3893787 Phase 2 [161]
Synonyms
PF-03893787; PF-3826719
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External Link
 Compound Name GPD-1116 Phase 2 [162]
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 Compound Name CTP-543 Phase 2 [163]
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 Compound Name MEMP1972A Phase 2 [164]
Synonyms
RG7449
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External Link
 Compound Name LCB-2183 Phase 2 [165]
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 Compound Name Flezelastine Phase 2 [166]
Synonyms
D-18024
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External Link
 Compound Name SR-2640 Phase 2 [167]
Synonyms
SR 2640; SR 2640 Hydrochloride; 105350-26-3; CHEMBL18132; SR2640; Benzoic acid, 2-[[3-(2-quinolinylmethoxy)phenyl]amino]-; QMPB; Benzoic acid, 2-((3-(2-quinolinylmethoxy)phenyl)amino)-; SR-01000076219; Tocris-1804; Lopac-S-7690; AC1L2TN9; Lopac0_001079; 2-(3-(2-Quinolylmethoxy)phenylamino)benzoic acid; MLS002153402; cid_128355; GTPL3329; SCHEMBL9119607; CTK8F0698; CHEBI:104023; HMS3263G20; HMS2236C03; ZINC596951; HMS3373N15; Tox21_501079; BDBM50006798; AKOS030239522; LP01079; CCG-205156; NCGC00015965-02; NCGC00015965-04
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External Link
 Compound Name PEGylated pitrakinra Phase 2 [168]
Synonyms
Aeroderm; Dermalast; AER-003; PEGylated pitrakinra (subcutaneous, eczema/allergy), Aerovance; PEGylated AER-001 (subcutaneous, eczema/allergy), Aerovance; PEGylated IL-4 variant (subcutaneous, eczema/allergy), Aerovance
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External Link
 Compound Name Gallopamil Phase 2 [169]
Synonyms
16662-47-8; methoxyverapamil; 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile; Galopamilo; Galopamilo [INN-Spanish]; Gallopamillum [INN-Latin]; Gallopamil [INN:BAN]; D600; D 600; C28H40N2O5; CHEBI:34772; (+/-)-Methoxyverapamil hydrochloride; 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile; Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4,5-trimethoxy-alpha-(1-methylethyl)-; GSK 796406
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 Compound Name ETX-9101 Phase 2 [170]
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 Compound Name MEDI9929 Phase 2 [150]
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 Compound Name MRx-4DP0004 Phase 1/2 [171]
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 Compound Name Sodium pyruvate Phase 1/2 [172]
Synonyms
113-24-6; Pyruvic acid sodium salt; sodium 2-oxopropanoate; Pyruvic acid, sodium salt; Propanoic acid, 2-oxo-, sodium salt; Sodium alpha-ketopropionate; 2-Oxopropanoic acid sodium salt; UNII-POD38AIF08; POD38AIF08; CHEBI:50144; Natriumpyruvat; alpha-Ketopropionic acid sodium salt; MFCD00002586; Propanoic acid, 2-oxo-, sodium salt (1:1); S-6005; Pyruvic acid, sodium salt, 99+%; Pyruvate Sodium; Natrum pyruvicum; CHEMBL181886; sodiumpyruvate; Guna-flam; Guna-hypertension; EINECS 204-024-4; pyruvic acid na-salt; N-115; Sodium pyruvate (inhaled); Reactive oxygen species antagonist (inhaled), EmphyCorp; Sodium pyruvate (inhaled), EmphyCorp
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 Compound Name GDC-0214 Phase 1 [173]
Synonyms
1831144-46-7; AKOS040759985; BDBM232517; CHEMBL3964801; EX-A6434; GDC0214; GDC-0214; GTPL12318; iJak-381; N-(3-(5-Chloro-2-(difluoromethoxy)phenyl)-1-(2-(4-((2-cyanoethyl)(methyl)amino)piperidin-1-yl)-2-oxoethyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide; N-[3-[5-chloro-2-(difluoromethoxy)phenyl]-1-[2-[4-[2-cyanoethyl(methyl)amino]piperidin-1-yl]-2-oxoethyl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [3-(5-chloro-2-difluoromethoxy-phenyl)-1-(2-{4-[(2-cyano-ethyl)-methyl-amino]-piperidin-1-yl}-2-oxo-ethyl)-1H-pyrazol-4-yl]-amide; RG6151; RG-6151; SCHEMBL17271636; US9346815, 63
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 Compound Name AZD8630 Phase 1 [174]
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 Compound Name AZD4604 Phase 1 [175]
Synonyms
(2R)-N-[3-[5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide; (R)-N-(3-(5-fluoro-2- (2-fluoro-3- (methylsulfonyl)phenyl amino)pyrimidin-4-yl)- 1H-indol-7-yl)-3- methoxy-2-(4- methylpiperazin-1- yl)propanamide; (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide; 1-Piperazineacetamide, N-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1H-indol-7-yl)-alpha-(methoxymethyl)-4-methyl-, (alphaR)-; 2241039-81-4; AKOS040733485; AT39356; AZD4604; AZD-4604; BDBM488779; CHEMBL4447181; CS-0101485; EX-A5343; example 35 [WO2018134213A1]; GTPL11716; HY-126294; JAC34RRR7S; JAK1-IN-7; londamocitinib; MS-30607; SCHEMBL20399395; UNII-JAC34RRR7S; US10961228, Example 35
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 Compound Name ADL 018 Phase 1 [176]
Synonyms
Omalizumab biosimilar
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 Compound Name KN-002 Phase 1 [177]
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 Compound Name GSK2292767 Phase 1 [178]
Synonyms
1254036-66-2; 4M4E8NZ73C; AC-32649; AKOS032945160; BCP24323; BDBM50521218; C24H28N6O5S; CCG-269791; CHEMBL4434674; compound 2 [PMID: 30532965]; compound 3 [PMID: 26301626]; CS-0003832; EX-A994; GSK2292767; GSK-2292767; GTPL10633; HY-15280; Methanesulfonamide, N-(5-(4-(5-(((2R,6S)-2,6-dimethyl-4-morpholinyl)methyl)-2-oxazolyl)-1H-indazol-6-yl)-2-methoxy-3-pyridinyl)-, rel-; Methanesulfonamide, N-[5-[4-[5-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]-2-oxazolyl]-1H-indazol-6-yl]-2-methoxy-3-pyridinyl]-, rel-; MFCD22572737; N-(5-(4-(5-(((2R,6S)-2,6-Dimethylmorpholino)methyl)oxazol-2-yl)-1H-indazol-6-yl)-2-methoxypyridin-3-yl)methanesulfonamide; n-[5-[4-(5-{[(2r,6s)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1h-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide; N-[5-[4-[5-[[(2S,6R)-2,6-Dimethylmorpholin-4-yl]methyl]-1,3-oxazol-2-yl]-1H-indazol-6-yl]-2-methoxypyridin-3-yl]methanesulfonamide; N-{5-[4-(5-{[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-methoxypyridin-3-yl}methanesulfonamide; PI3Kdelta inhibitor GS2292767; Q27464135; rel-N-[5-[4-[5-[[(2R,6S)-2,6-Dimethyl-4-morpholinyl]methyl]-2-oxazolyl]-1H-indazol-6-yl]-2-methoxy-3-pyridinyl]methanesulfonamide; s7938; SCHEMBL173490; UNII-4M4E8NZ73C
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 Compound Name SAR443765 Phase 1 [179]
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 Compound Name AMG 104 Phase 1 [180]
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 Compound Name ARO-RAGE Phase 1 [181]
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 Compound Name UPB-101 Phase 1 [182]
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 Compound Name BI 894416 Phase 1 [183]
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 Compound Name AZD0449 Phase 1 [184]
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 Compound Name CSL311 Phase 1 [185]
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 Compound Name BI 443651 Phase 1 [186]
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 Compound Name ARO-MUC5AC Phase 1 [187]
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 Compound Name RO-5271983 Phase 1 [188]
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 Compound Name AM-211 Phase 1 [189]
Synonyms
UNII-SZB129M7SZ; 1175526-27-8; SZB129M7SZ; CHEMBL2181753; AM211; [1,1'-Biphenyl]-3-acetic acid, 2'-[[ethyl[[(phenylmethyl)amino]carbonyl]amino]methyl]-6-methoxy-4'-(trifluoromethyl)-; SCHEMBL138450; DTXSID80151807; OPXIRFWNLBDKQB-UHFFFAOYSA-N; BDBM50397640; SB17010; HY-13213; CS-0003178; [2'-(3-benzyl-1-ethyl-ureidomethyl)-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid
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 Compound Name SAR-21609 Phase 1 [190]
Synonyms
TLR9 agonist (asthma/viral respiratory tract infection), sanofi-aventis
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 Compound Name SB-436811 Phase 1 [191]
Synonyms
CHEMBL366221; 346729-66-6; Benzamide,3,4-dichloro-N-[(3S)-1-[[4-[3-(dimethylamino)propoxy]phenyl]methyl]-3-pyrrolidinyl]-; SCHEMBL6949936; GTPL2164; ZINC3964101; BDBM50240963; KB-74923; 3,4-Dichloro-N-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-benzamide; (S)-3,4-dichloro-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)benzamide; (S)-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
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 Compound Name OPK-0018 Phase 1 [192]
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 Compound Name MEDI4212 Phase 1 [193]
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 Compound Name IMA-026 Phase 1 [194]
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 Compound Name AI-128 Phase 1 [195]
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 Compound Name PF-06444752 Phase 1 [196]
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 Compound Name Xmab-7195 Phase 1 [197]
Synonyms
IgE inhibitor (asthma/allergy), Xencor
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 Compound Name CNTO-3157 Phase 1 [198]
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 Compound Name CVT-6883 Phase 1 [199]
Synonyms
752222-83-6; GS-6201; UNII-67CKV7X08G; CHEMBL260933; 67CKV7X08G; CVT 6883; GS 6201; 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione; 3-ethyl-1-propyl-8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-1H-purine-2,6(3H,7H)-dione; Kinome_3621; SCHEMBL238694; GTPL5615; CVT6883; AOB4675; MolPort-035-765-814; CTV-6883; ZINC29055563; BDBM50236738; AKOS024458311; API0004749; 3-ethyl-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]pyrazol-4-yl]-7H-purine-2,6-dione
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 Compound Name FP-025 Phase 1 [200]
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 Compound Name BM-212 Phase 1 [201]
Synonyms
BM212; UNII-U9HSU4GZWL; 146204-42-4; U9HSU4GZWL; 1-{[1,5-Bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl}-4-methylpiperazine; 1-[[1,5-bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl]-4-methylpiperazine; BM 212; AC1L9VRH; CHEMBL321077; SCHEMBL1452627; BCP24821; ZINC22445591; AKOS032944899; CS-5953; Piperazine, 1-((1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methyl-; HY-100725
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 Compound Name CI-959 Phase 1 [202]
Synonyms
UNII-1A8130P4IY; CI 959; CI 159; 104795-68-8; 1A8130P4IY; Benzo(b)thiophene-2-carboxamide, 5-methoxy-3-(1-methylethoxy)-N-1H-tetrazol-5-yl-, monosodium salt; DSSTox_RID_82225; DSSTox_CID_27268; DSSTox_GSID_47268; DTXSID8047268; CHEMBL3183386; Tox21_300435; NCGC00254320-01; LS-41129
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 Compound Name AMG 282 Phase 1 [203]
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 Compound Name RX-10001 Phase 1 [204]
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 Compound Name PF-06413367 Phase 1 [205]
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 Compound Name GSK1440115 Phase 1 [206]
Synonyms
UNII-GCT6G5G3C7; GCT6G5G3C7; GSK 1440115; SCHEMBL2957737; 4'-(1-(((6,7-Dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetyl)(methyl)amino)-2-(4-morpholinyl)ethyl)-4-diphenylcarboxylic acid; (1,1'-Biphenyl)-4-carboxylic acid, 4'-((1R)-1-((2-(6,7-dichloro-2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)acetyl)methylamino)-2-(4-morpholinyl)ethyl)-
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 Compound Name Laevo-Bambuterol Phase 1 [207]
Synonyms
R-Bambuterol; R-bambuterol hydrochloride
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 Compound Name INO-4885 Phase 1 [208]
Synonyms
FP-15; INO-1080; Peroxynitrite decomposition catalyst, Inotek; WW-85; Reactive oxygen species inhibitor (contrast induced nephropathy), Inotek
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 Compound Name AZD1419 Phase 1 [209]
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 Compound Name SDZ-MKS-492 Phase 1 [210]
Synonyms
MKS-492
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 Compound Name VALERGEN-DS Phase 2 [211]
Synonyms
Dermatophagoides siboney allergen immunotherapy (subcutaneous, asthma), National Biopreparations Center
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 Compound Name CNT0-3157 Phase 1 [198]
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 Compound Name GSK-2239633 Phase 1 [212]
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 Compound Name GRC-6211 Phase 1 [213]
Synonyms
Oxolinic acid; 14698-29-4; Nidantin; Prodoxol; Prodoxal; Emyrenil; Dioxacin; Gramurin; Oxolinic; Oksaren; Ossian; Uroxol; Utibid; Urotrate; Uritrate; Pietil; Oxoboi; Ultibid; Starner; Acido oxolinico; Uro-alvar; Acide oxolinique; Acidum oxolinicum; Cistopax; Tiurasin; Orthurine; Acido ossolico; 5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid; NSC-110364; Urinox; Acido ossolico [DCIT]; 5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid; 1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid; GRC-6127; TRPV1 antagonists (asthma), Glenmark/Lilly; TRPV1 antagonists (incontinence), Glenmark/Lilly; TRPV1 antagonists (pain), Glenmark/Lilly; Transient receptor potential vanilloid sub-family 1 (pain), Glenmark/ Lilly; Vanilloid receptor VR1 antagonists (incontinence/pain/asthma), Glenmark/Lilly
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 Compound Name Clinprost Discontinued in Preregistration [214]
Synonyms
Arteon; Isocarbacyclin methyl ester; TEI-9090; TTC-909; Clinprost (liposomal), Taisho; Clinprost (liposomal), Teijin
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 Compound Name Fosfructose Discontinued in Phase 3 [215]
Synonyms
Cordox; Fosfructose trisodium; CPC-111; FDP, Questcor; Fructose-1,6-diphosphate; Fructose-1,6-diphosphate, Questcor
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 Compound Name DG031 Discontinued in Phase 3 [216]
Synonyms
Veliflapon; 128253-31-6; Bay-x-1005; Bay X 1005; DG-031; Bayx-1005; Bay X1005; UNII-JXH6X663L0; Bay-X1005; BAY 1005; DG 031; CHEMBL88712; JXH6X663L0; 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid; Benzeneacetic acid, alpha-cyclopentyl-4-(2-quinolinylmethoxy)-, (R)-; C23H23NO3; BAY-X 1005; (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid; Veliflapon [USAN:INN]; Velifapon; Veliflapon (USAN/INN); AC1L3X6M; MLS006010705; Benzeneacetic acid, a-cyclopentyl-4-(2-quinolinylmethoxy)-,(aR)-; GTPL5148
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 Compound Name Broxaterol Discontinued in Phase 3 [217]
Synonyms
Summair; Z-1170
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 Compound Name Lenercept Discontinued in Phase 3 [218]
Synonyms
Tenefuse; RsTNFR-IgG1; Ro-45-2081; TNF receptor-Ig, Roche; TNFR-IgG1 fusion protein, Roche
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 Compound Name BN 50730 Discontinued in Phase 3 [219]
Synonyms
Rocepafant; UNII-4KGX1STY2N; BN-50730; 4KGX1STY2N; 132579-32-9; BN50730; 132418-36-1; 6-(2-Chlorophenyl)-9-((4-methoxyphenyl)thiocarbamoyl)-1-methyl-7,8,9,10-tetrahydro-4H-pyrido(4',3'-4,5)thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine; 4H-Pyrido(4',3'-4,5)thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-9(8H)-carbothioamide, 6-(2-chlorophenyl)-7,10-dihydro-N-(4-methoxyphenyl)-1-methyl-; Rocepafant [INN]; LAU8080; LAU-8080; LAU 8080; AC1MHWNG; C27H25ClN6OS; SCHEMBL1065775; CHEMBL2105298; ZINC1481916; LS-172840
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 Compound Name Ablukast Discontinued in Phase 3 [220]
Synonyms
Ablukast sodium; RO-23-3544
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 Compound Name FOROPAFANT Discontinued in Phase 3 [221]
Synonyms
SR-27417; 2-[N-[2-(Dimethylamino)ethyl]-N-(3-pyridylmethyl)amino]-4-(2,4,6-triisopropylphenyl)thiazole
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 Compound Name Ataprost Discontinued in Phase 3 [222]
Synonyms
ONO-41483; OP-41483
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 Compound Name Bamaquimast Discontinued in Phase 2 [223]
Synonyms
L-0042; N-Methylcarbamic acid 3-(2-oxo-1-propyl-1,2-dihydroquinoxalin-3-yl)propyl ester;3-[3-(Methylcarbamoyloxy)propyl]-1-propylquinoxalin-2(1H)-one
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 Compound Name GSK159802 Discontinued in Phase 2 [224]
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 Compound Name TIBENELAST Discontinued in Phase 2 [225]
Synonyms
LY-186655 (sodium salt); 5,6-Diethoxybenzothiophene-2-carboxylic acid
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 Compound Name FK-613 Discontinued in Phase 2 [226]
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 Compound Name Pumafentrine Discontinued in Phase 2 [227]
Synonyms
Pumafentrin; BY-343; BYK-33043
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 Compound Name Nolpitantium besilate Discontinued in Phase 2 [228]
Synonyms
SR-140333; SR-140333B
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 Compound Name BUTIXOCORT Discontinued in Phase 2 [229]
Synonyms
JO-1717; 11beta,17-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione 17-butyrate; 17-Butanoyloxy-11beta-hydroxy-21-mercaptopregn-4-ene-3,20-dione
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 Compound Name LY-223982 Discontinued in Phase 2 [230]
Synonyms
CGS-23131; LY-223980; LY-255253; SKF-107324
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 Compound Name GSK256066 Discontinued in Phase 2 [231]
Synonyms
GSK-256066
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 Compound Name SC-45662 Discontinued in Phase 2 [232]
Synonyms
CHEMBL84566; UNII-TPG7IO601I component ADVNUIUADIXWMI-QWHCGFSZSA-N; 2-[[(1S,2R)-2-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylpropyl]oxy]acetic acid
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 Compound Name E-6123 Discontinued in Phase 2 [233]
Synonyms
E 6123; 131614-02-3; BRN 4280434; E- 6123; 4H-Pyrido(4',3':4,5)thieno(3,2-f)(1,2,4)triazolol(4,3-a)(1,4)diazepine, 6-(2-chlorophenyl)-9-(cyclopropylcarbonyl)-7,8,9,10-tetrahydro-1,4-dimethyl-, (S)-; 4H-Pyrido(4',3':4,5)thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine, 7,8,9,10-tetrahydro-6-(2-chlorophenyl)-9-(cyclopropylcarbonyl)-1,4-dimethyl-, (S)-; AC1MHYY4; CHEMBL114014; DTXSID20157146; API0009208; HY-10164; LS-134356
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 Compound Name EPI-2010 Discontinued in Phase 2 [234]
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 Compound Name SRP 299 Discontinued in Phase 2 [235]
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 Compound Name Valategrast Discontinued in Phase 2 [236]
Synonyms
220847-86-9; Valategrast (R411); UNII-06DM4KX7JG; 06DM4KX7JG; Valategrast [INN]; SCHEMBL480224; CHEMBL2107792; ZINC72190226; KB-81423; 2-(Diethylamino)ethyl N-(2-chloro-6-methylbenzoyl)-4-(2,6-dichlorobenzamido)-L-phenylalaninate
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 Compound Name APC-366 Discontinued in Phase 2 [237]
Synonyms
UNII-TGP1HP0WBC; TGP1HP0WBC; APC 366; 178925-65-0; apc366; N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide hydrochloride; APC-366 hydrochloride; AC1L42OQ; SCHEMBL15659721; APC-366-C; APC-366-A; APC-366-R; L-Prolinamide, N2-((1-hydroxy-2-naphthalenyl)carbonyl)-L-arginyl-, monohydrochloride; (2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[(1-hydroxynaphthalene-2-carbonyl)amino]pentanoyl]pyrrolidine-2-carboxamide hydrochloride
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 Compound Name GW-766994 Discontinued in Phase 2 [238]
Synonyms
CCR3 antagonists, GSK; CCR3 antagonists, GlaxoSmithKline; Chemokine receptor 3 antagonist, GlaxoSmithKline; GW-633647; GW-633647X; GW-701877; GW-701897; GW-701897X; GW-782415X; SB-297006; SB-328437
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 Compound Name LTB 019 Discontinued in Phase 2 [239]
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 Compound Name WAY-123641 Discontinued in Phase 2 [240]
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 Compound Name MK-591 Discontinued in Phase 2 [241]
Synonyms
Quiflapon; Quiflapon [INN]; L 686708; MK 0591; MK 591; L-686708; MK-0591; L-686,708; 3-(1-(4-chlorobenzyl-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl))-2,2-dimethyl propanoic acid; 3-(tert-Butylthio)-1-(p-chlorobenzyl)-alpha,alpha-dimethyl-5-(2-quinolylmethoxy)indole-2-propionic acid; 3-(tert-butylthio)-1-(p-chlorobenzyl)-a,a-dimethyl-5-(2-quinolylmethoxy)indole-2-propionic acid; 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid
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 Compound Name AVAC Discontinued in Phase 2 [242]
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 Compound Name CI-949 Discontinued in Phase 2 [243]
Synonyms
CI 949; UNII-EM1J51043X; EM1J51043X; L-Arginine, compd. with 5-methoxy-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H-indole-2-carboxamide (1:1); OHOCQQJBKBVAFF-VWMHFEHESA-N; AC1L4M1L; AC1Q5G9U; 121530-58-3; SCHEMBL17041896; n5-(diaminomethylidene)-l-ornithine- 5-methoxy-1-phenyl-3-(propan-2-yloxy)-n-(2h-tetrazol-5-yl)-1h-indole-2-carboxamide(1:1); LS-21607; 5-Methoxy-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H-indole-2-carboxamide L-arginate salt; (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid
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 Compound Name Imitrodast Discontinued in Phase 2 [244]
Synonyms
Logran; CS-518; RS-5186
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 Compound Name MK-886 Discontinued in Phase 2 [245]
Synonyms
118414-82-7; MK 886; MK886; 3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid; UNII-080626SQ8C; QAOAOVKBIIKRNL-UHFFFAOYSA-N; L-663,536; CHEMBL29097; CHEBI:75390; L 663536; MK-886 (L-663,536); 080626SQ8C; 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid; 1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-Alpha,Alpha-dimethyl-5-(1-methylethyl)- [CAS]; L-663536; SMR000466278
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 Compound Name Picumeterol Discontinued in Phase 2 [246]
Synonyms
Levopicumeterol; Picumeterol fumarate; GX 63411; GR-114297; GR-114297A; GR-114297X; GR-63411
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External Link
 Compound Name Sulukast Discontinued in Phase 2 [247]
Synonyms
LY-170680
    Click to Show/Hide
External Link
 Compound Name AR-D-111421 Discontinued in Phase 2 [248]
External Link
 Compound Name DS-4574 Discontinued in Phase 2 [249]
Synonyms
DS 4574; 118314-35-5; 6-(2-Cyclohexylethyl)-(1,3,4)thiadiazolo(3,2-a)-1,2,3-triazolo(4,5-d)pyrimidin-9(1H)-one; (1,3,4)Thiadiazolo(3,2-a)-1,2,3-triazolo(4,5-d)pyrimidin-9(1H)-one, 6-(2-cyclohexylethyl)-; [1,3,4]Thiadiazolo[3,2-a]-1,2,3-triazolo[4,5-d]pyrimidin-9(3H)-one,6-(2-cyclohexylethyl)-; AC1L4LXR; ACMC-20c9t1; AC1Q6E9S; SCHEMBL156066; CTK4B0638; DTXSID80152096; AKOS030534249; 6-(2-cyclohexylethyl)[1,3,4]thiadiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidin-9(2h)-one; LS-150402
    Click to Show/Hide
External Link
 Compound Name Nafagrel Discontinued in Phase 2 [250]
Synonyms
Nafagrel hydrochloride; DP-1904; SR-96325
    Click to Show/Hide
External Link
 Compound Name AS-35 Discontinued in Phase 2 [251]
Synonyms
AS 35; 108427-72-1; 9-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one; C21H20N6O4; 4H-Pyrido[1,2-a]pyrimidin-4-one,9-[(4-acetyl-3-hydroxy-2-propylphenoxy)methyl]-3-(2H-tetrazol-5-yl)-; 4H-Pyrido(1,2-a)pyrimidin-4-one, 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-; RVRGDCZGEKSIRW-UHFFFAOYSA-N; ACMC-20mbio; as35; AC1L2WU8; SCHEMBL159227; CTK4A6033; DTXSID90148546; CS-7624; LS-134160; HY-101946; L003846
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External Link
 Compound Name RPR-106541 Discontinued in Phase 2 [252]
External Link
 Compound Name AZD-3778 Discontinued in Phase 2 [253]
Synonyms
CHEMBL2158814; SCHEMBL5418656; GTPL7679; AZD3778; QVLZVRFIGXNZMN-UHFFFAOYSA-N; AZD 3778; BDBM50394155; N-[[4-(3,4-Dichlorophenoxy)[1,4'-bipiperidin]-1'-yl]carbonyl]-4-methyl-benzenesulfonamide
    Click to Show/Hide
External Link
 Compound Name V-11294A Discontinued in Phase 2 [254]
Synonyms
Rolipram derivatives, Napp
    Click to Show/Hide
External Link
 Compound Name Corus 1030 Discontinued in Phase 2 [255]
Synonyms
Inhaled Lidocaine
    Click to Show/Hide
External Link
 Compound Name R-343 Discontinued in Phase 2 [256]
Synonyms
R-921303; Syk tyrosine kinase inhibitor (allergic asthma), Rigel/Pfizer
    Click to Show/Hide
External Link
 Compound Name ZD-2138 Discontinued in Phase 2 [257]
Synonyms
Ici D2138; 140841-32-3; UNII-B6G6OX1ZH5; B6G6OX1ZH5; CHEMBL20403; 2(1H)-Quinolinone,6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl-; Ici-D2138; 6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-methylquinolin-2(1H)-one; ZD 2138; ACMC-20mzth; AC1L30RD; zd2138; 6-((3-Fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-methylquinol-2-one; SCHEMBL1083603; CTK4C2357; DTXSID90161477; BDBM50000829; AKOS025404954; ACN-048395
    Click to Show/Hide
External Link
 Compound Name GSK2190914 Discontinued in Phase 2 [258]
External Link
 Compound Name IVL745 Discontinued in Phase 2 [236]
Synonyms
F387KG9Ith; UNII-F387KG9ITH; XRP 1745A; IVL 745; SCHEMBL6136116; DTXSID9043930; NOCAS_43930; IVL-745; 229627-58-1; beta-Alanine, N-((3-methoxy-4-((((2-methylphenyl)amino)carbonyl)amino)phenyl)acetyl)glycyl-N-((3,4-dimethoxyphenyl)methyl)-
    Click to Show/Hide
External Link
 Compound Name Isbufylline Discontinued in Phase 2 [259]
Synonyms
TE/06
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External Link
 Compound Name GSK2190915 Discontinued in Phase 2 [260]
Synonyms
1093403-33-8; sirtuin modulator; SRT 2104; SRT2104 (GSK2245840); SRT2104; SRT-2104; UNII-4521NR0J09; 4521NR0J09; 5-Thiazolecarboxamide, 4-methyl-N-[2-[3-(4-morpholinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-(3-pyridinyl)-; C26H24N6O2S2; 4-Methyl-N-(2-{3-[(morpholin-4-yl)methyl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl)-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide; 4-methyl-n-(2-(3-(morpholinomethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-(pyridin-3-yl)thiazole-5-carboxamide
    Click to Show/Hide
External Link
 Compound Name ACREOZAST Discontinued in Phase 2 [261]
Synonyms
TYB-2285; N,N'-(2-Chloro-5-cyano-1,3-phenylene)bis[2-(acetyloxy)acetamide]; 3,5-Bis(2-acetoxyacetamido)-4-chlorobenzonitrile
    Click to Show/Hide
External Link
 Compound Name FK-011 Discontinued in Phase 2 [262]
External Link
 Compound Name KW-4490 Discontinued in Phase 2 [263]
External Link
 Compound Name Tetrazolast meglumine Discontinued in Phase 2 [264]
Synonyms
Tetrazolast; Tetrazolast meglumine salt monohydrate; MDL-26024; MDL-26024GO
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External Link
 Compound Name Mequitamium iodide Discontinued in Phase 2 [265]
Synonyms
LG-30435
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External Link
 Compound Name Milveterol Discontinued in Phase 2 [266]
Synonyms
UNII-LGY1VQ9622; LGY1VQ9622; 652990-07-3; Milveterol [INN]; SCHEMBL265694; CHEMBL1940832; DTXSID30215640; BMKINZUHKYLSKI-DQEYMECFSA-N; BDBM50419652
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External Link
 Compound Name FK-224 Discontinued in Phase 2 [267]
Synonyms
FR-115224
    Click to Show/Hide
External Link
 Compound Name CGRP Discontinued in Phase 2 [268]
Synonyms
Calcitonin gene related peptide; LAB CGRP; CGRP (inhaled, asthma); CGRP (inhaled, asthma), Akela Pharma; Calcitonin gene-related peptide (inhaled, asthma), LAB International
    Click to Show/Hide
External Link
 Compound Name GSK870086 Discontinued in Phase 2 [269]
External Link
 Compound Name CJ-13610 Discontinued in Phase 2 [270]
Synonyms
CJ 13610; CJ-13,610
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External Link
 Compound Name E-6080 Discontinued in Phase 2 [271]
Synonyms
E 6080; 120164-49-0; E6080; AC1L2UXT; SCHEMBL3053845; DTXSID10152706; 6-Hydroxy-2-(4-sulfamoylbenzylamine)-4,5,7-trimethylbenzothiazole hcl; 6-hydroxy-2-(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazole hydrochloride; Benzenesulfonamide, 4-(((6-hydroxy-4,5,7-trimethyl-2-benzothiazolyl)amino)methyl)-, monohydrochloride; 4-[[(6-hydroxy-4,5,7-trimethyl-1,3-benzothiazol-2-yl)amino]methyl]benzenesulfonamide hydrochloride
    Click to Show/Hide
External Link
 Compound Name CI-1018 Discontinued in Phase 2 [272]
Synonyms
UNII-Y4O6325SYW; Y4O6325SYW; CHEMBL111925; DSSTox_CID_27248; DSSTox_RID_82208; DSSTox_GSID_47248; SCHEMBL185627; CAS-NOCAS_47248; DTXSID0047248; NOCAS_47248; Tox21_300203; BDBM50217550; NCGC00254191-01; NCGC00247925-01; 179024-48-7; PD-168787; (+)-CI-1018; CI-1018, (+)-; UNII-05127JZ9KQ component KYFWUBJMTHVBIF-QFIPXVFZSA-N; 4-Pyridinecarboxamide, N-(3,4,6,7-tetrahydro-9-methyl-4-oxo-1-phenylpyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-, (R)-; 4-Pyridinecarboxamide, N-((3R)-3,4,6,7-tetrahydro-9-methyl-4-oxo-1-phenylpyrrol
    Click to Show/Hide
External Link
 Compound Name SK&F-S-106203 Discontinued in Phase 2 [273]
Synonyms
SK&F-106203; (S)-beta-[(2-Carboxyethyl)thio]-2-(8-phenyloctyl)benzenepropanoic acid; 3(S)-[2-(Carboxyethyl)thio]-3-[2-(8-phenyloctyl)phenyl]propionic acid
    Click to Show/Hide
External Link
 Compound Name AVE-5883 Discontinued in Phase 1/2 [274]
External Link
 Compound Name NCX 950 Discontinued in Phase 1/2 [275]
External Link
 Compound Name Vepalimomab Discontinued in Phase 1/2 [276]
Synonyms
Vapantix; VAP-1 MAb (1), BioTie Therapies
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External Link
 Compound Name RO7040547 Discontinued in Phase 1 [277]
Synonyms
BITS7201A; RG7990
    Click to Show/Hide
External Link
 Compound Name PF-3526299 Discontinued in Phase 1 [278]
External Link
 Compound Name IPLl576092 Discontinued in Phase 1 [279]
Synonyms
IPL 576,092
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External Link
 Compound Name SB-281832 Discontinued in Phase 1 [280]
External Link
 Compound Name SDZ-PCO-400 Discontinued in Phase 1 [281]
Synonyms
PCO-400
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External Link
 Compound Name F-11105 Discontinued in Phase 1 [282]
External Link
 Compound Name SMART anti-E/P selectin Discontinued in Phase 1 [283]
Synonyms
HuEP5C7; Bispecific anti-E/P selectin, PDL; SMART anti-E/P selectin, PDL; SMART anti-E/P selectin, Protein Design Labs; Anti-E/P selectin (humanized), PDL
    Click to Show/Hide
External Link
 Compound Name NIP-520 Discontinued in Phase 1 [284]
Synonyms
NIP-502
    Click to Show/Hide
External Link
 Compound Name ABT-080 Discontinued in Phase 1 [285]
Synonyms
VML-530; 4,4-Bis[4-(quinolin-2-ylmethoxy)phenyl]pentanoic acid sodium salt
    Click to Show/Hide
External Link
 Compound Name YM-976 Discontinued in Phase 1 [286]
Synonyms
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
    Click to Show/Hide
External Link
 Compound Name RG-7152 Discontinued in Phase 1 [287]
Synonyms
5-[3-[3-(2-Quinolinylmethoxy)phenoxy]propyl]-1H-tetrazole
    Click to Show/Hide
External Link
 Compound Name HSR-6071 Discontinued in Phase 1 [288]
Synonyms
PTPC; 6-(1-Pyrrolidinyl)-N-(1H-tetrazol-5-yl)pyrazine-2-carboxamide
    Click to Show/Hide
External Link
 Compound Name AZD-1744 Discontinued in Phase 1 [289]
Synonyms
Dual CCR3/H-1 receptor antagonist (chronic obstructive pulmonary disease (COPD)), AstraZeneca
    Click to Show/Hide
External Link
 Compound Name AMG 317 Discontinued in Phase 1 [290]
External Link
 Compound Name PF-05212372 Discontinued in Phase 1 [291]
Synonyms
PLA-950; Asthma therapy (inhaled, asthma), Pfizer; Asthma therapy (inhaled, asthma), Wyeth
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External Link
 Compound Name GR-63799X Discontinued in Phase 1 [292]
Synonyms
(-)-[1(R)-[1alpha(Z),2beta(R*),3alpha]-7-[3-Hydroxy-2-(2-hydroxy-3-phenoxypropoxy)-5-oxocyclopentyl]-4-heptenoic acid 4-(benzoylamino)phenyl ester; (Z)-4,5-Didehydro-13-oxa-16-phenoxy-13,14-dihydro-17,18,19,20-tetranor-PGE1 4-(benzoylamino)phenyl ester; 119906-28-4
    Click to Show/Hide
External Link
 Compound Name RWJ-56423 Discontinued in Phase 1 [293]
Synonyms
CHEMBL256892; CHEMBL124571; (2S,4R)-1-ACETYL-N-[(1S)-4-[(AMINOIMINOMETHYL)AMINO]-1-(2-BENZOTHIAZOLYLCARBONYL)BUTYL]-4-HYDROXY-2-PYRROLIDINECARBOXAMIDE; (2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide; AC1NR9Y0; SCHEMBL4314345; GTPL9333; VXDAVYUFYPFGDX-SNPRPXQTSA-N; BDBM50228764; BDBM50131977; DB02812; (2S)-6; (4R)-1-acetyl-N-[(1S)-1-(1,3-benzothiazol-2-ylcarbonyl)-4-carbamimidamidobutyl]-4-hydroxy-L-prolinamide
    Click to Show/Hide
External Link
 Compound Name ABN-912 Discontinued in Phase 1 [294]
Synonyms
Anti-CD46 mAb, Novartis; Anti-MCP1 monoclonal antibody, Novartis
    Click to Show/Hide
External Link
 Compound Name CGP-13774 Discontinued in Phase 1 [295]
External Link
 Compound Name NZ-107 Discontinued in Phase 1 [296]
Synonyms
4-Bromo-5-(3-ethoxy-4-methoxybenzylamino)pyridazin-3(2H)-one
    Click to Show/Hide
External Link
 Compound Name TR-14531 Discontinued in Phase 1 [297]
Synonyms
IDDB25065
    Click to Show/Hide
External Link
 Compound Name RG-7185 Discontinued in Phase 1 [298]
Synonyms
CRTH2 antagonist (asthma), Roche
    Click to Show/Hide
External Link
 Compound Name BM-113 Discontinued in Phase 1 [299]
Synonyms
1-[2-(Benzhydryloxy)ethyl]piperidine-4-acetic acid ethyl ester
    Click to Show/Hide
External Link
 Compound Name GW-250495 Discontinued in Phase 1 [300]
Synonyms
GR-250495; GR-250495X; GW-250495X
    Click to Show/Hide
External Link
 Compound Name SMP-028 Discontinued in Phase 1 [301]
External Link
 Compound Name YM-355179 Preclinical [302]
Synonyms
GTPL793; SCHEMBL3808393
    Click to Show/Hide
External Link
 Compound Name AZD-1678 Preclinical [303]
Synonyms
CCR4 antagonist (asthma), AstraZeneca
    Click to Show/Hide
External Link
 Compound Name LAS-101057 Preclinical [304]
Synonyms
LAS-38096; Adenosine A2b receptor antagonists (inflammation), Almirall
    Click to Show/Hide
External Link
 Compound Name YM-344031 Preclinical [76]
External Link
 Compound Name IMO-2134 Preclinical [305]
External Link
 Compound Name FPL-55712 Terminated [306]
Synonyms
40786-08-1; 7-((3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxyl))-4-oxo-8-propyl-4H-chromene-2-carboxy late, sodium salt; CHEMBL267976; 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]- 4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid sodium salt; 4H-1-Benzopyran-2-carboxylic acid, 7-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy)-4-oxo-8-propyl-, monosodium salt; fpl55712; SCHEMBL1890293; AOB5208; ZDEVPOBNLIVGFA-UHFFFAOYSA-M; MFCD00068619; LS-186693; FT-0639668; FPL-55712, &gt
    Click to Show/Hide
External Link
 Compound Name LY-255283 Terminated [307]
Synonyms
GTPL3351; MolPort-009-018-745; HMS3649C08; ZINC27644044; SR-01000946596; SR-01000946596-1
    Click to Show/Hide
External Link
 Compound Name A-78773 Terminated [308]
Synonyms
141579-67-1; A 78773; CHEMBL59598; N-Hydroxy-N-(4-(5-(4-fluorophenoxy)-2-furyl)-3-butyn-2-yl)urea; N-(3-(5-(4-Fluorophenoxy)-2-furanyl)-1-methyl-2-propynyl)-N-hydroxyurea; 1-{4-[5-(4-fluorophenoxy)furan-2-yl]but-3-yn-2-yl}-1-hydroxyurea; 1-[4-[5-(4-fluorophenoxy)furan-2-yl]but-3-yn-2-yl]-1-hydroxyurea; Urea,N-[3-[5-(4-fluorophenoxy)-2-furanyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-; CCRIS 8531
    Click to Show/Hide
External Link
 Compound Name SKF-96231 Terminated [309]
External Link
 Compound Name BAY-44-3428 Terminated [310]
Synonyms
APC-1167
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External Link
 Compound Name KA-398 Terminated [311]
Synonyms
Scopinast; Scopinast, Wilmar Schwabe
    Click to Show/Hide
External Link
 Compound Name Fenspiride hydrochloride Terminated [312]
Synonyms
KSP-193
    Click to Show/Hide
External Link
 Compound Name SM 11044 Terminated [313]
Synonyms
142784-65-4; SM-11044; DTXSID90162181; AC1L3144; 3-(3,4-Dihydroxyphenyl)-N-(3-(4-fluorophenyl)propyl)serine pyrrolidine amide hydrobromide; Pyrrolidine, 1-(3-(3,4-dihydroxyphenyl)-2-((3-(4-fluorophenyl)propyl)amino)-3-hydroxy-1-oxopropyl)-, monohydrobromide, (R-(R*,S*))-; (2S,3R)-3-(3,4-dihydroxyphenyl)-2-[3-(4-fluorophenyl)propylamino]-3-hydroxy-1-pyrrolidin-1-ylpropan-1-one hydrobromide
    Click to Show/Hide
External Link
 Compound Name BI-L-357 Terminated [314]
Synonyms
BI-L-226
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External Link
 Compound Name FR-113680 Terminated [315]
Synonyms
FR 113680; 126088-92-4; Ac-Thr-trp(cho)-phe-N-mebzl; AC1L2Y4S; DTXSID70155076; fr113680; N(alpha)-(N(alpha)-(N(alpha)-Acetylthreonyl)-N(1)-formyltryptophyl)-N-methyl-N-(phenylmethyl)phenylalaninamide; L-Phenylalaninamide, N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-
    Click to Show/Hide
External Link
 Compound Name MEN-11149 Terminated [316]
External Link
 Compound Name KF-17625 Terminated [317]
Synonyms
KF17625; KF 17625; BRN 4874703; CHEMBL95509; 139339-02-9; 5-Phenyl-1H-imidazo(4,5-c)(1,8)naphthyridin-4(5H)-one; 1,5-Dihydro-5-phenyl-4H-imidazo(4,5-c)(1,8)naphthyridin-4-one; 4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 1,5-dihydro-5-phenyl-; AC1L2QF6; SCHEMBL2457079; DTXSID10161015; NDDBRRFHXNPOLY-UHFFFAOYSA-N; BDBM50230286; ZINC13731342; LS-80025; LS-80024; 5-phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4-one; 5-Phenyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one; 5-Phenyl-3H-Imidazo[4,5-c][1,8]Naphthyridin-4(5H) -One
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External Link
 Compound Name Tomelukast Terminated [318]
Synonyms
LY-171883
    Click to Show/Hide
External Link
 Compound Name MX2/120 Terminated [319]
Synonyms
155006-67-0; BRN 7252641; 7-(2,2-Dimethylpropyl)-1-methylxanthine; 1H-Purine-2,6-dione, 3,7-dihydro-7-(2,2-dimethylpropyl)-1-methyl-; 3,7-Dihydro-7-(2,2-dimethylpropyl)-1-methyl-1H-purine-2,6-dione; AC1MINF6; SCHEMBL3843737; 7-(2,2-dimethylpropyl)-1-methyl-3H-purine-2,6-dione; CTK4C8491; DTXSID90165793; 1-Methyl-7-(2,2-dimethylpropyl)xanthine; LS-126951
    Click to Show/Hide
External Link
 Compound Name UR-8308 Terminated [320]
External Link
 Compound Name UR-8328 Terminated [321]
External Link
 Compound Name OT-4003 Terminated [322]
Synonyms
IDDB10966
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External Link
 Compound Name Org-9935 Terminated [323]
Synonyms
Org-935
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External Link
 Compound Name MOL-218 Terminated [324]
Synonyms
MOL-254; MOL-268; MOL-294; NFkB inhibitors, Molecumetics
    Click to Show/Hide
External Link
 Compound Name LY-210073 Terminated [325]
Synonyms
LY210073; 148291-65-0; CHEMBL49210; LY 210073; SCHEMBL9148299; AC1O515S; BDBM50045092; HY-U00263; AKOS030562935; CS-7479; L005236; 5-(2-carboxyethyl)-6-[(E)-6-(4-methoxyphenyl)hex-5-enoxy]-9-oxoxanthene-2-carboxylic acid; 7-Carboxy-3-[[(E)-6-(4-methoxyphenyl)-5-hexenyl]oxy]-9-oxo-9H-xanthene-4-propanoic acid; (E)-7-Carboxy-3-((6-(4-methoxyphenyl)-5-hexenyl)oxy)-9-oxo-9H-xanthene-4-propanoic acid; 7-Carboxy-3-((6-(methoxyphenyl)-5(E)-hexenyl)oxy)-9-oxo-9H-xanthene-4-propanoic acid
    Click to Show/Hide
External Link
 Compound Name SC-53228 Terminated [326]
Synonyms
SC 53228; CHEMBL419948; 153633-01-3; AC1L4BTY; SCHEMBL1447495; DTXSID40165384; BDBM50037390; 3-[(2S)-7-[3-[2-(cyclopropylmethyl)-3-methoxy-4-(methylcarbamoyl)phenoxy]propoxy]-8-propyl-3,4-dihydro-2H-chromen-2-yl]propanoic acid; 3-{(S)-7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcarbamoyl-phenoxy)-propoxy]-8-propyl-chroman-2-yl}-propionic acid; 2H-1-Benzopyran-2-propanoic acid, 7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-, (S)-
    Click to Show/Hide
External Link
 Compound Name BAY-17-1998 Terminated [327]
Synonyms
BAY-35-8535
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External Link
 Compound Name A-79175 Terminated [328]
Synonyms
CHEMBL90552; UNII-25B75ID70W; 25B75ID70W; AC1L43J2; ZINC5333; SCHEMBL6438420; BDBM50369068; 141579-87-5; 1-[(2R)-4-[5-(4-fluorophenoxy)furan-2-yl]but-3-yn-2-yl]-1-hydroxyurea
    Click to Show/Hide
External Link
 Compound Name FK-355 Terminated [329]
Synonyms
NK1 antagonists, Fujisawa
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External Link
 Compound Name ICI-198615 Terminated [330]
Synonyms
Cyclopentyl N-[1-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]indazol-6-yl]carbamate; Ici 198615; 104448-53-5; CHEMBL22033; Ici-198,615; ZM 198615; ZM-198,615; cyclopentyl N-[1-({4-[(benzenesulfonyl)carbamoyl]-2-methoxyphenyl}methyl)-1H-indazol-6-yl]carbamate; [3H]ICI198615; [3H]-ICI198615; [3H]ICI-198615; [3H]ICI-198,615; AC1L3GQZ; (1-((2-Methoxy-4-(((phenylsulfonyl)amino)carbonyl)phenyl)methyl)-1H-indazol-6-yl)carbamic acid cyclopentyl ester; GTPL3414; GTPL3358; SCHEMBL9806720; DTXSID80146490; BDBM50009075; PDSP1_000520; PDSP2_000518; ICI198615
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External Link
 Compound Name SDZ-ISQ-844 Terminated [331]
Synonyms
143526-87-8; Sdz isq 844; SDZ ISQ-844; SCHEMBL7298437; AC1L317P; CTK4C3695; 3-Isoquinolinemethanol,1-(3,5-dimethoxyphenyl)-3,4-dihydro-6,7-dimethoxy-, (3S)-; AKOS030566039; 6,7-Dimethoxy-1-(3,4-dimethoxyphenyl)-3-hydroxymethyl-3,4-dihydroisoquinoline; (S)-1-(3,5-Dimethoxyphenyl)-3,4-dihydro-6,7-dimethoxy-3-isoquinolinemethanol; 3-Isoquinolinemethanol, 1-(3,5-dimethoxyphenyl)-3,4-dihydro-6,7-dimethoxy-, (S)-
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 Compound Name ON-579 Terminated [332]
Synonyms
141286-14-8; ON 579; 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethylsulfanyl]-2,6-difluorophenoxy]acetic acid; Acetic acid,2-[4-[[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]thio]-2,6-difluorophenoxy]-; ACMC-20cvej; AC1Q6UCK; AC1L4U4O; {4-[(2-{[(4-chlorophenyl)sulfonyl]amino}ethyl)sulfanyl]-2,6-difluorophenoxy}acetic acid; CHEMBL312763; SCHEMBL2925987; CTK4C2555; DTXSID70161657; AKOS030574939; 4-(2-(4-Chlorophenylsulfonylamino)-ethylthio)-2,6-difluorophenoxyacetic acid; KB-227077
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 Compound Name L-648051 Terminated [333]
Synonyms
4-Apsob; L 648051; UNII-0LGZ40MB45; 0LGZ40MB45; 91541-18-3; 4-((3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl)-gamma-oxobenzenebutanoic acid; 4-(4-{[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl]sulfonyl}phenyl)-4-oxobutanoic acid; Benzenebutanoic acid, 4-((3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl)-gamma-oxo-; AC1Q5VP2; AC1L3TT7; SCHEMBL157166; CHEMBL282253; CTK8D5118; DTXSID50238619; ZAKKEARLDPTRLX-UHFFFAOYSA-N; AKOS030530731; LS-186850; LS-187510
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 Compound Name ZD-7944 Terminated [334]
Synonyms
CHEMBL339767; ZD7944; SCHEMBL7501969; BDBM50409575; (R)-3-((S)-1-(3,4-dichlorophenyl)-3-(4-(2-((S)-methylsulfinyl)phenyl)piperidin-1-yl)propyl)-2-ethylisoindolin-1-one
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 Compound Name AZD-2098 Terminated [335]
External Link
 Compound Name BW B70C Terminated [336]
Synonyms
BWB70C; BW-B 70C; 134470-38-5; BW-B70C; CHEMBL86676; CHEBI:75307; (E)-N-(3-(3-(4-Fluorophenoxy)phenyl)-1-(R,S)-methylprop-2-enyl)-N-hydroxyurea; 70C; N-[3-[3-4(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea; N-(3-(3-(4-Fluorophenoxy)phenyl)-1-methyl-2-propenyl)-N-hydroxyurea; Urea, N-(3-(3-(4-fluorophenoxy)phenyl)-1-methyl-2-propenyl)-N-hydroxy-; C17H17FN2O3; SR-01000075717; (e)-N-{3-[3-(4-fluorophenoxy)phenyl]-1-(r,s)-methylprop-2-enyl}-N-hydroxyurea; Lopac0_000202; BSPBio_001512; SCHEMBL2681955
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 Compound Name CP-0597 Terminated [337]
External Link
 Compound Name Selenotifen Terminated [338]
Synonyms
BN-52256
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External Link
 Compound Name 443C81 Terminated [339]
Synonyms
BW 443C; BW-443C81
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External Link
 Compound Name ZT-386 Terminated [340]
External Link
 Compound Name EFIPLADIB Terminated [341]
Synonyms
381683-94-9; UNII-S97YUG2A91; S97YUG2A91; CHEMBL272342; PLA-902; Efipladib [USAN:INN]; Efipladib (USAN); 4-(3-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophenyl)methylsulfonamido)ethyl)-1H-indol-3-yl)propyl)benzoic acid; SCHEMBL1500831; HIZOPJQOPKRKFM-UHFFFAOYSA-N; ZINC85536943; BDBM50226792; D06674; 4-{3-[1-benzhydryl-5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1H-indol-3-yl]propyl}benzoic acid
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External Link
 Compound Name ZM-230487 Terminated [342]
Synonyms
ZM 230487; 155944-23-3; CHEMBL459236; Ici 230487; ICI-230487; AC1L31ZC; 1-Ethyl-6-((3-fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)phenoxy)methyl)-2-quinolone; SCHEMBL6008852; CTK4C8893; DTXSID70165998; zm230487; ZINC1484223; BDBM50250926; 1-Ethyl-6-((3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy)methyl)-2(1H)-quinolinone; KB-276139; 1-ethyl-6-[[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]methyl]quinolin-2-one
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External Link
 Compound Name LY-290154 Terminated [343]
External Link
 Compound Name BU-4601A Terminated [344]
Synonyms
BU-4601B; BU-4601C
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External Link
 Compound Name R zileuton Terminated [345]
External Link
 Compound Name UR-8225 Terminated [346]
Synonyms
UR 8225; 149455-36-7; 5,6-Dihydro-6,6-dimethyl-5-oxo-8-(2-oxo-1(2H)-pyridinyl)-2-naphthalenecarbonitrile; 1,2-Dihydro-4-(1,2-dihydro-2-oxo-1-pyridyl)-2,2-dimethyl-1-oxonaphthalene-6-carbonitrile; 2-Naphthalenecarbonitrile, 5,6-dihydro-6,6-dimethyl-5-oxo-8-(2-oxo-1(2H)-pyridinyl)-; 2-Naphthalenecarbonitrile,5,6-dihydro-6,6-dimethyl-5-oxo-8-(2-oxo-1(2H)-pyridinyl)-; ACMC-20n5pl; AC1L560X; SCHEMBL6369766; CHEMBL303682; CTK4C6217; DTXSID60164273; LS-94452
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 Compound Name AVE0675 Terminated [347]
External Link
 Compound Name L-670596 Terminated [348]
Synonyms
121083-05-4; L-670,596; L 670596; 2-(6,8-Difluoro-9-(4-(methylsulfonyl)benzyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid; (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID; AC1L2VGU; SCHEMBL3044967; CHEBI:91930; CTK8F0755; MolPort-003-983-606; HMS3268M18; BCP28232; BN0288; AKOS022180202; RT-013483; FT-0757831; SR-01000597550; L002392; C-35484; SR-01000597550-1; J-004444; BRD-A85472596-001-01-4
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External Link
 Compound Name MCI-826 Terminated [349]
Synonyms
(E)-2,2-Diethyl-3'-[2-[2-(4-isopropyl)thiazolyl]ethenyl]succinanilic acid; (E)-2,2-Diethyl-N-[3-[2-(4-isopropylthiazol-2-yl)vinyl]phenyl]succinamic acid
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External Link
 Compound Name MDL-43291 Terminated [350]
Synonyms
Mdl 43291; Mdl 43,291; AC1MI0EN; ((Octahydro-2-oxo-7-tetradecylidene-2H-1-benzopyran-8-yl)thio)acetic acid; (4aalpha,7Z,8beta,8abeta)-((Octahydro-2-oxo-7-tetradecylidene-2H-1-benzopyran-8-yl)thio)acetic acid; Acetic acid, ((octahydro-2-oxo-7-tetradecylidene-2H-1-benzopyran-8-yl)thio)-, (4aalpha,7Z,8beta,8abeta)-; 2-[[(2Z,4aS,8S,8aS)-2-(2-oxotetradecan-7-ylidene)-3,4,4a,5,6,7,8,8a-octahydrochromen-8-yl]sulfanyl]acetic acid
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External Link
 Compound Name XR-12890 Terminated [351]
Synonyms
MRP1 inhibitor, Xenova; Multidrug resisitance protein inhibitor, Xenova
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External Link
 Compound Name CGS-13080 Terminated [352]
Synonyms
PIRMAGREL; Pirmagrelum [Latin]; Pirmgrel; Pirmagrel [USAN:INN]; UNII-9J5H2VA91V; CGS 13080; 85691-74-3; CHEMBL48092; 9J5H2VA91V; Imidazo(1,5-a)pyridine-5-hexanoic acid; Pirmagrelum; Imidazo[1,5-a]pyridine-5-hexanoic acid; Pirmagrel (USAN/INN); AC1L1IZ7; SCHEMBL636018; DTXSID80234982; LIFOFTJHFFTNRV-UHFFFAOYSA-N; ZINC2021333; BDBM50025953; imidazol(1,5-a)pyridine-5-hexanoic acid; LS-177888; 6-imidazo[1,5-a]pyridin-5-ylhexanoic acid; 5-(5-carboxypentyl)imidazo[1,5-a]pyridine; 5-(5-carboxypentyl)-imidazo[1,5-a]pyridine
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 Compound Name RG-14893 Terminated [353]
Synonyms
RG 14893; 141835-49-6; CHEMBL328712; 2-Naphthalenecarboxylicacid, 4-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-; ACMC-20n0x5; AC1L30VP; SCHEMBL1894401; rg14893; CTK0H7370; DTXSID30161835; BDBM50001609; 4-(2-(Methyl(2-phenylethyl)amino)-2-oxoethyl)-8-(phenylmethoxy)-2-naphthalenecarboxylic acid; 4-(2-(Methyl(2-phenethyl)amino)-2-oxoethyl)-8-(phenylmethoxy)-2-naphthalenecarboxylic acid; L006851; 8-Benzyloxy-4-[(methyl-phenethyl-carbamoyl)-methyl]-naphthalene-2-carboxylic acid
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External Link
 Compound Name Epocarbazolin-A Terminated [354]
Synonyms
Epocarbazolin-B
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External Link
 Compound Name NS-1619 Terminated [355]
Synonyms
153587-01-0; NS 1619; 1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one; NS1619; CHEMBL384903; 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one; CHEBI:34879; 1-(2'-Hydroxy-5'-trifluoromethylphenyl)-5-trifluoromethyl-2(3H)-benzimidazolone; 1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2h-benzimidazol-2-one; 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one
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 Compound Name U-78517F Terminated [356]
Synonyms
Troloxamine; U-78517; U-78517G; U-78518F; U-83836E
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External Link
 Compound Name GCC-AP0341 Terminated [357]
Synonyms
AP-0341
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External Link
 Compound Name RP-58802B Terminated [358]
Synonyms
Imoxiterol; 88578-07-8; Imoxiterolum; Imoxiterol [INN]; Imoxiterolum [Latin]; AC1L23PZ; SCHEMBL249468; CHEMBL2104918; RP 58802B; CS-6651; 2-(3-(1-Benzimidazolyl)-1-methylpropylamino)-1-(4-hydroxy-3-methoxyphenyl)ethanol; RP-58802; HY-101585; L007875; alpha-(((3-(1-Benzimidazolyl)-1-methylpropyl)amino)methyl)vanillyl alcohol
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 Compound Name WIN-64821 Terminated [359]
Synonyms
Q-20547A
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External Link
 Compound Name Sulotroban Terminated [360]
Synonyms
BM-13177; SKF-95587
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External Link
 Compound Name Ro 20-1724 Terminated [361]
Synonyms
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 29925-17-5; 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one; ro-20-1724; Ro 201724; CHEMBL18701; 4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one; 2-Imidazolidinone, 4-((3-butoxy-4-methoxyphenyl)methyl)-; RO-201724; 2-Imidazolidinone, 4-((3-butoxy-4-methoxyphenyl)methyl)-, (+-)-; 4-(3-butoxy-4-methoxy-benzyl)imidazolidin-2-one; 34185-37-0; 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone; SR-01000075647; keratan sulfate I; Keratan sulphate I; Naphthoquinone analogs
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 Compound Name ZD-7717 Terminated [362]
Synonyms
ICI D7717
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External Link
 Compound Name Isomazole Terminated [363]
Synonyms
Isosulmazole; Isomazole fumarate; Isomazole hydrochloride; EMD-41064; EMD-47200; EMD-50250; EMD-52750; LY-175326
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 Compound Name PLR-8 Terminated [364]
Synonyms
PLR-2224
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External Link
 Compound Name LF-801 Terminated [365]
External Link
 Compound Name L-745337 Terminated [366]
Synonyms
Thioflosulide; CHEMBL287919; 158205-05-1; L 745337; L 745,337; L-745,337; SCHEMBL2464202; ZINC1887701; BDBM50029603; CS-6783; N-(6-((2,4-Difluorophenyl)thio)-2,3-dihydro-1-oxo-1H-inden-5-yl)methanesulfonamide; HY-19217; L745,337
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 Compound Name CV 6209 Terminated [367]
Synonyms
CHEMBL274420; CV6209; GTPL1852; AC1L32P4; SCHEMBL8538219; CHEMBL1180101; PDSP1_000728; PDSP1_000727; PDSP2_000718; PDSP2_000717; BDBM50005232; 2-(2-Acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacosan-1-yl)-1-ethylpyridinium; 2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-propoxycarbonyl)-amino]-methyl}-1-ethyl-pyridinium; [2-methoxy-3-(octadecylcarbamoyloxy)propyl] N-acetyl-N-[(1-ethylpyridin-1-ium-2-yl)methyl]carbamate
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External Link
 Compound Name VZ-564 Terminated [368]
Synonyms
VZ 564; 147495-99-6; 1-hydroxy-1-[(6-methoxy-3,4-dihydronaphthalen-2-yl)methyl]urea; Urea,N-[(3,4-dihydro-6-methoxy-2-naphthalenyl)methyl]-N-hydroxy-; VZ564; ACMC-20cs2n; AC1Q5JDP; AC1L4U8C; SCHEMBL9448945; CTK4C5429; N-Hydroxy-N-(6-methoxy-3,4-dihydro-2-naphthylmethyl)urea; DTXSID80163728; Urea, 1-hydroxy-1-(6-methoxy-3,4-dihydro-2-naphthylmethyl)-
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 Compound Name MEN-10627 Terminated [369]
Synonyms
MEN10627; 157351-81-0; AC1NSKCE; GTPL3901; cyc(2beta-5beta)(Met-Asp-Trp-Phe-Dap-Leu); (1R,4S,7S,10R,13R,16S)-13-(1H-indol-3-ylmethyl)-4-(2-methylpropyl)-7-(2-methylsulfanylethyl)-16-(phenylmethyl)-3,6,9,12,15,18,20-heptazabicyclo[8.8.4]docosane-2,5,8,11,14,17,21-heptone
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 Compound Name RP-66153 Terminated [370]
Synonyms
RP 66153; CHEMBL108415; 142422-79-5; AC1L30YM; SCHEMBL4355829; DTXSID80162034; 2,2-Dimethyl-7-(3-(3-phenylpropyl)-2-thienyl)heptanoic acid; BDBM50001162; 2-Thiopheneheptanoic acid, alpha,alpha-dimethyl-3-(3-phenylpropyl); 2,2-dimethyl-7-[3-(3-phenylpropyl)thiophen-2-yl]heptanoic acid; 2,2-Dimethyl-7-[3-(3-phenyl-propyl)-thiophen-2-yl]-heptanoic acid
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 Compound Name KC-11404 Terminated [371]
External Link
 Compound Name TAK-225 Terminated [372]
Synonyms
2,2-Diethyl-3-(7-methyl[1,2,4]triazolo[1,5-b]pyridazin-6-yloxy)propanesulfonamide
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 Compound Name NPC-17731 Terminated [373]
Synonyms
Bradykinin antagonists, Scios; NPC-16731; NPC-17761; NPC-18521; NPC-18688; NPC-18884
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 Compound Name Midaglizole Terminated [374]
Synonyms
Midaglizole hydrochloride; DG 5218; DG-5128; Pyridine, 2-[2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl]-, monohydrochloride
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 Compound Name BABIM Terminated [375]
Synonyms
Bis(5-amidino-2-benzimidazolyl)methane; 74733-75-8; CHEMBL99951; 1H-Benzimidazole-5-carboximidamide, 2,2'-methylenebis-; 1xug; 1c1v; AC1L1DKB; SCHEMBL65730; AC1Q1U90; CTK5E0415; BDBM16127; DTXSID60225717; AIDS007118; ZINC3871731; AKOS028112598; Bis(5-amidino-1H-benzimidazole-2-yl)methane; 1H-Benzimidazole-6-carboximidamide,2,2'-methylenebis-; 2,2 -methanediylbis(1H-benzimidazole-6-carboximidamide); 2-[(5-carbamimidoyl-1H-benzimidazol-2-yl)methyl]-1H-benzimidazole-5-carboxamidine
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 Compound Name KF-15570 Terminated [376]
Synonyms
KF 15570; BRN 4872911; 4H-Imidazo(4,5-c)quinolin-4-one, 1,5-dihydro-5-butyl-1-methyl-; 133305-92-7; 5-Butyl-1-methyl-1,5-dihydro-1H-imidazo(4,5-c)quinolin-4(5H)-one; AC1MIPZT; SCHEMBL9215327; CHEMBL434802; DTXSID80158053; CVLGNWUGFVTZRC-UHFFFAOYSA-N; ZINC1548061; LS-80514; 5-butyl-1-methylimidazo[4,5-c]quinolin-4-one; 5-butyl-1-methyl-1h-imidazo[4,5-c]quinolin-4(5h)-one; 5-n-Butyl-1-methyl-1H,5H-imidazo[4,5-c]quinolin-4-one
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 Compound Name GW-3600 Terminated [377]
Synonyms
Phosphodiesterase 4 inhibitor, Glaxo
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 Compound Name KC-11425 Terminated [378]
External Link
 Compound Name LM-1376 Terminated [379]
External Link
 Compound Name Sch-45752 Terminated [380]
Synonyms
Cephalochromin; MLS000876993; CHEMBL463175; NSC627953; NSC201419; 25908-26-3; SMR000440611; cefalochromin; 5,6,8-trihydroxy-2-methyl-9-(5,6,8-trihydroxy-2-methyl-4-oxo-2,3-dihydrobenzo[g]chromen-9-yl)-2,3-dihydrobenzo[g]chromen-4-one; Sch 45752; AC1Q6DTF; AC1L4N2K; SCHEMBL1111561; MEGxm0_000312; cid_160115; ACon0_000585; ACon1_000126; MolPort-001-739-590; HMS2270H11; BDBM50269745; NSC-201419; NSC-627953; MCULE-6609850631; NCGC00180856-01; SR-01000758207; SR-01000758207-2
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External Link
 Compound Name EP-012637 Terminated [381]
Synonyms
Ciclosporin analogs, Enanta; Cyclosporin A analogs, Enanta; Cyclosporine analogs, Enanta; EP-1269; EP-314; EP-861; Immunosuppressant program, Enanta
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 Compound Name IDR-1002 Investigative [382]
External Link
 Compound Name Vagonixen Investigative [383]
External Link
 Compound Name RS-1748 Investigative [384]
External Link
 Compound Name BFPT-12603 Investigative [383]
Synonyms
BFPT-2603
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External Link
 Compound Name LPCN-1056 Investigative [383]
Synonyms
LPCN-1052
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External Link
 Compound Name AEOL-11207 Investigative [383]
Synonyms
AEOL-11203; AEOL-11216; Catalytic antioxidants, Aeolus; Catalytic antioxidants, Incara
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External Link
 Compound Name GATA-3-specific DNAzyme Investigative [383]
Synonyms
GATA-3-specific DNAzyme (asthma); GATA-3-specific DNAzyme (asthma), Philipps-Universitat Marburg/sterna biologicals; Gd21 GATA-3-specific DNAzyme (asthma), Philipps-Universitat Marburg/sterna biologicals
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External Link
 Compound Name BW-858C Investigative [385]
External Link
 Compound Name PXS-4159 Investigative [386]
Synonyms
Membrane copper amine oxidase modulators (asthma), Pharmaxis; SSAO/VAP-1 inhibitors (asthma), Pharmaxis
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 Compound Name IW-1221 Investigative [387]
Synonyms
CRTH2 inhibitor (asthma), Ironwood
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 Compound Name N-6060 Investigative [388]
Synonyms
N-6338; N-6371; N-6446; N-6463; N-6501; N-6537; N-6603; S-nitrosoglutathione reductase inhibitors, N30
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 Compound Name SP-003 Investigative [383]
Synonyms
SP-003, PhytoPharmacon; Euphorbia hirta-derived anti-inflammatory (oral, asthma), PhytoPharmacon
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External Link
 Compound Name NPT-CLN Investigative [383]
Synonyms
Calcineurin inhibitors (asthma), Biotica; NPT-CLN series (inhaled, asthma); NPT-CLN series (inhaled, asthma), Biotica
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External Link
 Compound Name Sulochrin Investigative [383]
Synonyms
519-57-3; UNII-8NA53C271Z; CHEBI:16159; 8NA53C271Z; Methyl 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoate; Benzoic acid, 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-, methyl ester; Sulochrin_120096; AC1Q5ZJI; AC1L4NQS; MLS000863634; SCHEMBL233392; CHEMBL61133; MEGxm0_000192; CTK1H2445; ACon0_000926; ACon1_000208; DTXSID80199860; MolPort-001-739-420; YJRLSCDUYLRBIZ-UHFFFAOYSA-N; HMS2268H19; ZINC895263; MFCD07370145; ACM519573; Sulochrin, > AKOS030615357; MCULE-7066877679
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 Compound Name LMS-611 Investigative [383]
Synonyms
LMS-611 (inhalant), Lamellar Biomedical; LMS-611 (oral), Lamellar Biomedical
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 Compound Name AG-NCA805 Investigative [383]
External Link
 Compound Name ER-23006 Investigative [389]
External Link
 Compound Name Anti-TSLP mab Investigative [383]
Synonyms
Anti-TSLP mAb (asthma)
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External Link
 Compound Name APX-E Investigative [383]
Synonyms
AXP-A0; AXP-D; CCR3 antagonists (asthma); CCR3 antagonists (asthma), Axikin
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External Link
 Compound Name L-873724 Investigative [390]
Synonyms
UNII-29250PP3ON; 603139-12-4; CHEMBL437501; 29250PP3ON; (2S)-N-(cyanomethyl)-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]Pentanamide; (2S)-N-(cyanomethyl)-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide; VYFDSJLOCIGIKP-SFTDATJTSA-N; GTPL7860; SCHEMBL2157182; BDBM19489; (+)-L-873724; ZINC34802820; CS-6814; HY-50887; Pentanamide, N-(cyanomethyl)-4-methyl-2-(((1S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)(1,1'-biphenyl)-4-yl)eth
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External Link
 Compound Name MAR--99 Investigative [391]
Synonyms
BRN 5609020
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External Link
 Compound Name DW-403 Investigative [383]
External Link
 Compound Name UR-60427 Investigative [392]
Synonyms
Histamine H4 inverse agonist (asthma), Palau Pharma
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External Link
 Compound Name HMPL-342 Investigative [383]
Synonyms
HM-A42; I-kappa beta kinase inhibitor (asthma/COPD/autoimmune diseases), Hutchison Medipharma
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External Link
 Compound Name OT-121 Investigative [383]
Synonyms
OT-121 (inhaled dry powder, asthma); OT-121 (inhaled dry powder, asthma), Oriel Therapeutics; OT-121 (inhaled dry powder, asthma),Sandoz
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External Link
 Compound Name VALERGENT-BT Investigative [393]
Synonyms
VALERGEN-BT (subcutaneous); Blomia tropicalis allergen immunotherapy (sc, asthma), National Biopreparations Center
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External Link
 Compound Name AIM-101 Investigative [383]
Synonyms
AIM-101 (Neutropel, asthma/COPD), AIM Therapeutics
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External Link
 Compound Name CH-3697 Investigative [394]
External Link
 Compound Name MER-2101 Investigative [383]
Synonyms
Epitope-driven vaccine + MAS-1 adjuvant (asthma), Mercia
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External Link
 Compound Name BCP-1081 Investigative [383]
Synonyms
Non-steroidal anti-inflammatory agent (asthma), BioCure Pharma; Non-steroidal anti-inflammatory agent (asthma), InflammoGen
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External Link
 Compound Name DS-AH-14 Investigative [395]
External Link
 Compound Name ASOBAMAST Investigative [396]
Synonyms
Asobamast < Rec INN; Z-1819; N-[4-(3-Methylisoxazol-5-yl)thiazol-2-yl]oxamic acid 2-ethoxyethyl ester
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External Link
 Compound Name FHT-CT4 Investigative [383]
Synonyms
CTLA4-PTD fusion protein (inflammation), Forhumantech
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External Link
 Compound Name HD-101 Investigative [383]
Synonyms
Antibody (asthma/autoimmune disease), Dreampharma
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External Link
 Compound Name Recombinant anti-IgE Fabs Investigative [383]
Synonyms
Recombinant anti-IgE Fabs (asthma/immunological diseases); Anti-immunoglobulin E antibodies (asthma/immunological disease), Glycobia; Recombinant anti-IgE Fabs (asthma/immunological diseases), Glycobia; Recombinant anti-immunoglobulin E antigen binding fragments (asthma/immunological diseases), Glycobia
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External Link
 Compound Name VBP Investigative [383]
Synonyms
VBP series (muscular dystrophy/asthma); VBP series (muscular dystrophy/asthma), Validus Biopharma; Non-hormonal steroids (spinal muscular atrophy/amyotropic lateral sclerosis/Duchenne dystrophy/asthma), Validus Biopharma
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External Link
 Compound Name GSK-172981 Investigative [397]
Synonyms
GSK-256471; SB-218795; SB-235375; SB-244487; SB-400238; SB-414240; SK-797230; NK-2 antagonists, GSK; NK-3 antagonists, GlaxoSmithKline; NK-3 antagonists, SB
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External Link
 Compound Name ATL-844 Investigative [398]
Synonyms
N-(4-Cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide; MRS 1754; 264622-58-4; MRS-1754; MRS1754; CHEMBL273807; N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide; [3H]MRS1754; [3H]-MRS1754; NCGC00015689-01; Lopac-M-6316; Lopac0_000729; GTPL453; GTPL449; MLS002153324; SCHEMBL1222380; AC1O7G54; CTK8E7916; CHEBI:93269; AOB5542; DTXSID80424967; MolPort-023-276-567; HMS3373J21; HMS3268F13; HMS2230A06; ZINC4475274; BDBM50086170; AKOS027427086; AKOS024457276; EX-3306; ATL-618; ATL-GW-22; ATL-GW-8; A2B adenosine receptor antagonists, Adenosine/Ortho-McNeil; A2B adenosine receptor antagonists (oral, asthma/diabetes), Adenosine Therapeutics; A2B adenosine receptor antagonists (oral, asthma/diabetes), Clinical Data
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External Link
 Compound Name TA-106 Investigative [399]
Synonyms
FAb antibody fragment (inflammation), Taligen Therapeutics; Anti-factor B FAb (inflammation), Alexion
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External Link
 Compound Name HL-028 Investigative [383]
External Link
 Compound Name PRS-060 Investigative [400]
Synonyms
IL-4 alpha receptor inhibitor (Anticalin, asthma), Pieris; IL-4R alpha inhibitor (Anticalin, asthma), Pieris
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External Link
 Compound Name KI-0905 Investigative [383]
External Link
 Compound Name RV-1088 Investigative [383]
External Link
 Compound Name CWF-0710 Investigative [383]
External Link
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Ref 83 ClinicalTrials.gov (NCT04540042) A Two Part, Randomised, Double-blind, Placebo-controlled, Phase 2 Parallel Group Study to Evaluate the Safety and Efficacy of Intravenously-Administered SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and to Evaluate the Safety and Efficacy of Intravenously-Administered SelK2 in Subjects With Chronic Obstructive Pulmonary Disease (Part 2). U.S.National Institutes of Health.
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Ref 87 ClinicalTrials.gov (NCT04092582) A Phase IIa, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MTPS9579A in Patients With Asthma Requiring Inhaled Corticosteroids and a Second Controller. U.S.National Institutes of Health.
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Ref 97 ClinicalTrials.gov (NCT01551147) A Placebo and Active Controlled Study of ONO-6950 Following Allergen Challenge in Patients With Asthma. U.S. National Institutes of Health.
Ref 98 ClinicalTrials.gov (NCT00843193) Efficacy and Safety Study of GSK679586 in Patients With Severe Asthma. U.S. National Institutes of Health.
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Ref 101 ClinicalTrials.gov (NCT00758446) Efficacy and Safety Study of BLX-028914 in Subjects With Allergic Rhinitis. U.S. National Institutes of Health.
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Ref 214 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003132)
Ref 215 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005137)
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Ref 217 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000105)
Ref 218 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004745)
Ref 219 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001346)
Ref 220 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002358)
Ref 221 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1856).
Ref 222 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002073)
Ref 223 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006975)
Ref 224 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021784)
Ref 225 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000078)
Ref 226 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003074)
Ref 227 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013080)
Ref 228 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2107).
Ref 229 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002075)
Ref 230 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3415).
Ref 231 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024245)
Ref 232 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001362)
Ref 233 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001351)
Ref 234 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009338)
Ref 235 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015332)
Ref 236 Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.Nat Rev Drug Discov. 2016 Aug;15(8):533-50.
Ref 237 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003595)
Ref 238 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3530).
Ref 239 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015581)
Ref 240 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003918)
Ref 241 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001712)
Ref 242 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014452)
Ref 243 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000104)
Ref 244 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000225)
Ref 245 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2655).
Ref 246 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002942)
Ref 247 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3327).
Ref 248 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013264)
Ref 249 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000587)
Ref 250 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000433)
Ref 251 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001439)
Ref 252 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007341)
Ref 253 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7679).
Ref 254 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012597)
Ref 255 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017745)
Ref 256 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027577)
Ref 257 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001835)
Ref 258 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026047)
Ref 259 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000109)
Ref 260 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027280)
Ref 261 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002325)
Ref 262 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010718)
Ref 263 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017153)
Ref 264 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001730)
Ref 265 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000086)
Ref 266 Emerging drugs in chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2009 Mar;14(1):181-94.
Ref 267 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2103).
Ref 268 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022730)
Ref 269 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024246)
Ref 270 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5169).
Ref 271 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001952)
Ref 272 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010034)
Ref 273 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000042)
Ref 274 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021516)
Ref 275 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012159)
Ref 276 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016990)
Ref 277 ClinicalTrials.gov (NCT02748642) A Study to Investigate the Safety, Pharmacokinetics, and Immunogenicity of BITS7201A in Healthy Volunteers and Participants With Mild Atopic Asthma. U.S. National Institutes of Health.
Ref 278 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027922)
Ref 279 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015217)
Ref 280 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016500)
Ref 281 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001697)
Ref 282 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010557)
Ref 283 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008129)
Ref 284 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012535)
Ref 285 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009466)
Ref 286 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5292).
Ref 287 Induction of peroxisomal enzymes by a tetrazole-substituted 2-quinolinylmethoxy leukotriene D4 antagonist. Fundam Appl Toxicol. 1994 Aug;23(2):298-303.
Ref 288 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000116)
Ref 289 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025772)
Ref 290 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017312)
Ref 291 ClinicalTrials.gov (NCT01415102) A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.. U.S. NationalInstitutes of Health.
Ref 292 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1937).
Ref 293 Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone. J Med Chem. 2003 Aug 28;46(18):3865-76.
Ref 294 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020409)
Ref 295 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004654)
Ref 296 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000068)
Ref 297 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012564)
Ref 298 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033115)
Ref 299 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013013)
Ref 300 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010129)
Ref 301 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024745)
Ref 302 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 793).
Ref 303 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030818)
Ref 304 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5617).
Ref 305 Clinical pipeline report, company report or official report of Idera Pharmaceuticals (2011).
Ref 306 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000089)
Ref 307 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3351).
Ref 308 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003598)
Ref 309 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003084)
Ref 310 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010843)
Ref 311 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007218)
Ref 312 Fenspiride in patients with acute bronchitis. Pol Merkur Lekarski. 2005 Jul;19(109):32-6.
Ref 313 The iodocyanopindolol and SM-11044 binding protein belongs to the TM9SF multispanning membrane protein superfamily. Gene. 2001 Aug 8;273(2):227-37.
Ref 314 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002162)
Ref 315 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001352)
Ref 316 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009948)
Ref 317 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002336)
Ref 318 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000075)
Ref 319 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005445)
Ref 320 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005294)
Ref 321 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005293)
Ref 322 Discovery of OT4003, a novel, potent, and orally active cys-LT1 receptor antagonist. Bioorg Med Chem. 1997 Feb;5(2):415-27.
Ref 323 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010891)
Ref 324 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009549)
Ref 325 Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.
Ref 326 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006478)
Ref 327 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007862)
Ref 328 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004773)
Ref 329 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014508)
Ref 330 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3358).
Ref 331 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005292)
Ref 332 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003601)
Ref 333 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000103)
Ref 334 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007349)
Ref 335 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020384)
Ref 336 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002163)
Ref 337 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008984)
Ref 338 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001341)
Ref 339 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000227)
Ref 340 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004057)
Ref 341 Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib. J Med Chem. 2008 Jun 26;51(12):3388-413.
Ref 342 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005134)
Ref 343 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007201)
Ref 344 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005261)
Ref 345 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026867)
Ref 346 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002580)
Ref 347 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027402)
Ref 348 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000341)
Ref 349 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001711)
Ref 350 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000087)
Ref 351 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013041)
Ref 352 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000262)
Ref 353 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001715)
Ref 354 Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. J Antibiot (Tokyo). 1993 Jan;46(1):25-33.
Ref 355 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4272).
Ref 356 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002333)
Ref 357 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008073)
Ref 358 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001694)
Ref 359 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005879)
Ref 360 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000039)
Ref 361 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5258).
Ref 362 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007338)
Ref 363 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000373)
Ref 364 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022513)
Ref 365 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012974)
Ref 366 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005419)
Ref 367 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1852).
Ref 368 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004801)
Ref 369 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3901).
Ref 370 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003980)
Ref 371 Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application in asthma. J Med Chem. 1995 Feb 17;38(4):669-85.
Ref 372 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007361)
Ref 373 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 657).
Ref 374 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000085)
Ref 375 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010022)
Ref 376 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002335)
Ref 377 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006447)
Ref 378 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005461)
Ref 379 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006199)
Ref 380 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002639)
Ref 381 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017492)
Ref 382 Disrupting Tryptophan in the Central Hydrophobic Region Selectively Mitigates Immunomodulatory Activities of the Innate Defence Regulator Peptide IDR-1002. J Med Chem. 2021 May 27;64(10):6696-6705.
Ref 383 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
Ref 384 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 61).
Ref 385 Effect of BW B70C, a novel inhibitor of arachidonic acid 5-lipoxygenase, on allergen-induced bronchoconstriction and late-phase lung eosinophil accumulation in sensitised guinea-pigs. Agents Actions.1993 Jan;38(1-2):8-18.
Ref 386 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).
Ref 387 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).
Ref 388 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2613).
Ref 389 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 29).
Ref 390 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7860).
Ref 391 Effect of 1,6-dihydro-2[2-(2-methylpropoxy)anilino]-6-oxo-5-pyrimidineca rboxyli c acid on ethanol-induced microvascular injury in rats. Arzneimittelforschung. 1996 Aug;46(8):779-83.
Ref 392 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 265).
Ref 393 CA patent application no. 747325, Albumin fusion proteins.
Ref 394 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1300).
Ref 395 US patent application no. 5,446,057, Substituted tetrahydropyridine and piperidine carboxylic acids as muscarinic antagonists.
Ref 396 Regulation of leukotriene biosynthesis. Cancer Metastasis Rev. 1994 Dec;13(3-4):257-67.
Ref 397 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5774).
Ref 398 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 449).
Ref 399 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2339).
Ref 400 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1697).