m6A-centered Crosstalk Information

Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT03533
 [1], [2]
Histone modification H3K4me3 WDR5 ALKBH5 Direct Enhancement m6A modification TP53 TP53 ALKBH5 Demethylation : m6A sites
m6A Modification:
m6A Regulator RNA demethylase ALKBH5 (ALKBH5) ERASER
 Regulator Info 
m6A Target Cellular tumor antigen p53 (TP53/p53)
 Targert Gene 
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type Histone modification (HistMod)
Epigenetic Regulator WD repeat-containing protein 5 (WDR5) WRITER View Details
Regulated Target Histone H3 lysine 4 trimethylation (H3K4me3) View Details
Downstream Gene ALKBH5 View Details
Crosstalk Relationship Histone modification  →  m6A Enhancement
Crosstalk Mechanism histone modification directly impacts m6A modification through modulating the level of m6A regulator
Crosstalk Summary Mechanically, the highly expressed ALKBH5 is induced by HBx-mediated Histone H3 lysine 4 trimethylation (H3K4me3) modification of ALKBH5 gene promoter in a WDR5-dependent manner after HBV infection. The increased ALKBH5 protein catalyzes the m6A demethylation of HBx mRNA, thus stabilizing and favoring a higher HBx expression level. Deletion of METTL16 or ALKBH5 predicted poor OS and DFS of hepatocellular carcinoma (HCC) patients. And this study found significant associations between the genetic alterations and clinicopathological features as well as Cellular tumor antigen p53 (TP53/p53) alteration.
Responsed Disease Liver cancer ICD-11: 2C12
 Disease Info 
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
Cellular tumor antigen p53 (TP53/p53) 27 Compound(s) Regulating the Target Click to Show/Hide the Full List
 Compound Name Contusugene ladenovec Phase 3 [3]
Synonyms
Advexin; Ad5CMV-p53; INGN-004; INGN-201; Ad-p53, Introgen; Gene therapy (p53/adenovirus), University of Texas; Gene therapy (p53/adenoviral), Introgen/Aventis; Gene therapy (p53/adenoviral), Introgen/RPR
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MOA Modulator
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TTD: D04FYL
 Compound Name QPI-1002 Phase 3 [4]
MOA Modulator
External Link
TTD: D0D5ZU
 Compound Name Thymoquinone Phase 2/3 [5]
Synonyms
490-91-5; Thymoquinon; p-Cymene-2,5-dione; 2-Isopropyl-5-methyl-1,4-benzoquinone; 2,5-CYCLOHEXADIENE-1,4-DIONE, 2-METHYL-5-(1-METHYLETHYL)-; 2-Isopropyl-5-methyl-p-benzoquinone; 2-Isopropyl-5-methylbenzoquinone; Polythymoquinone; 5-Isopropyl-2-methyl-1,4-benzoquinone; 2-Isopropyl-5-methylbenzo-1,4-quinone; p-Mentha-3,6-diene-2,5-dione; NSC 2228; 2-Isopropyl-5-methylcyclohexa-2,5-diene-1,4-dione; 2-Methyl-5-isopropyl-p-benzoquinone; 2-methyl-5-propan-2-ylcyclohexa-2,5-diene-1,4-dione; NSC2228; 2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-dione; UNII-O60IE26NUF; 2-Methyl-5-isopropyl-1,4-benzoquinone; O60IE26NUF; 2,5-Cyclohexadiene-1,4-dione, 5-isopropyl-2-methyl-; NSC-2228; 5-Isopropyl-2-methyl-p-benzoquinone; MFCD00001602; 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione; p-Mentha-3,6-diene-2,5-dione (8CI); 5-Isopropyl-2-methyl-2,5-Cyclohexadiene-1,4-dione; CCRIS 7152; EINECS 207-721-1; 2-methyl-5-(methylethyl)cyclohexa-2,5-diene-1,4-dione; BRN 1939047; thymolquinone; Thymoil; AI3-17758; 4hco; p-Mentha-3,5-dione; Spectrum_001237; SpecPlus_000457; Thymoquinone, >=98%; Spectrum2_000700; Spectrum3_001345; Spectrum4_001895; Spectrum5_000550; BSPBio_003129; KBioGR_002455; KBioSS_001717; DivK1c_006553; SCHEMBL542535; SPBio_000859; CHEMBL1672002; DTXSID9060079; KBio1_001497; KBio2_001717; KBio2_004285; KBio2_006853; KBio3_002349; Thymoquinone, analytical standard; CHEBI:113532; 2-Methyl-5-iso-propylbenzoquinone; BDBM166686; ZINC164367; BCP16946; HY-D0803; WLN: L6V DVJ B1 EY1&1; 2,4-dione, 5-isopropyl-2-methyl-; ANW-41600; CCG-40027; s4761; SBB008296; AKOS003368628; MCULE-9899033250; NCGC00178250-01; NCGC00178250-05; 73940-92-8; AK101679; AS-11327; 2-Isopropyl-5-methylbenzo-1,4-quinone #; 2,4-dione, 2-methyl-5-(1-methylethyl)-; CS-0012226; FT-0612708; ST45023960; K-9199; SR-05000002192; Q7799650; SR-05000002192-2; W-202869; BRD-K97566842-001-03-5; 2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-dione (F8); 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 9CI
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MOA Inhibitor
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CID: 10281
TTD: DY4OZ6
 Compound Name SGT-53 Phase 2 [6]
Synonyms
P53 gene stimulator (solid tumor), Synergene Therapeutics
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MOA Stimulator
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TTD: D02EOH
 Compound Name APR-246 Phase 2 [7]
Synonyms
Eprenetapopt
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MOA Stimulator
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CID: 52918385
TTD: D03XTY
DrugBank: DB11684
 Compound Name Ad-p53 Phase 2 [8]
Synonyms
P53 gene therapy, Transgene/Schering-Plough; Ad-p53, Transgene/Schering-Plough
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MOA Modulator
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TTD: D0CO9B
 Compound Name Kevetrin Phase 2 [9]
MOA Stimulator
External Link
CID: 437740
TTD: D0K7DV
DrugBank: DB13010
 Compound Name INGN-225 Phase 2 [10]
Synonyms
Cancer vaccine (p53), Introgen
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External Link
TTD: D0V2SP
 Compound Name ALT-801 Phase 2 [11]
Synonyms
ALT-801 (donor lymphocyte infusion, cancer); ALT-801 (donor lymphocyte infusion, cancer), Altor; STAR IL-2 conjugate (donor lymphocyte infusion, cancer), Altor; STAR-Ck (donor lymphocyte infusion, cancer), Altor; Soluble T-cell Antigen Receptor IL-2 conjugate (donor lymphocyte infusion, cancer), Altor
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MOA Immunomodulator (Immunostimulant)
External Link
TTD: D0V5JH
 Compound Name APG-115 Phase 2 [9]
Synonyms
15Qau0SI9J; UNII-15QAU0SI9J; 1818393-16-6; APG 115 [WHO-DD]; SCHEMBL17189805; Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-1'',2''-dihydro-2''-oxodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-(3H)indol)-5'-yl)carbonyl)amino)-
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MOA Inhibitor
External Link
CID: 91972012
TTD: D04SXL
 Compound Name ISA-P53-01 Phase 1/2 [12]
Synonyms
P53-SLP; P53 vaccine (colorectal/ovarian cancer), ISA Pharmaceuticals; P53 vaccine (Montanide ISA-51 adjuvanted, colorectal/ovarian cancer), ISA Pharmaceuticals
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External Link
TTD: D0KK4N
 Compound Name SAR-405838 Phase 1 [13]
Synonyms
AT-219; MI-147; MI-219; MI-319; MI-43; MI-5; MI-63; MI-772; MI-773; MI-519-64; P53-HDM2 protein interaction inhibitors (cancer); P53-HDM2 protein interaction inhibitors (cancer), Ascenta/Sanofi; P53-HDM2 protein interaction inhibitors (cancer), Ascenta/sanofi-aventis
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MOA Modulator
External Link
CID: 53476877
TTD: D03YSQ
DrugBank: DB12541
 Compound Name Dendritic cell vaccine Phase 1 [14]
Synonyms
Dendritic cell vaccine (injectable, head and neck cancer); Dendritic cell vaccine (injectable, head and neck cancer), National Cancer Institute; Mutant p53 peptide pulsed dendritic cell vaccine (injectable, head and neck cancer), National Cancer Institute
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External Link
TTD: D05CPS
 Compound Name ONYX-015 Phase 1 [15]
Synonyms
Dl1520; E1B-deleted adenovirus (cancer), ONYX
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MOA Modulator
External Link
TTD: D0G7YS
 Compound Name COTI-2 Phase 1 [9]
Synonyms
UNII-2BTA1O65BR; 2BTA1O65BR; 1039455-84-9; ZINC114475331; CS-8156; HY-19896; 1-Piperazinecarbothioic acid, 4-(2-pyridinyl)-, 2-(6,7-dihydro-8(5H)-quinolinylidene)hydrazide
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MOA Modulator
External Link
CID: 91810660
TTD: D0G8CU
 Compound Name CGM097 Phase 1 [4]
MOA Modulator
External Link
CID: 53240420
TTD: D0Q7AG
 Compound Name HDM201 Phase 1 [16]
MOA Inhibitor
External Link
CID: 71678098
TTD: D01KTG
 Compound Name INGN-234 Discontinued in Phase 2 [17]
Synonyms
P53 tumor suppressor (topical formulation), Introgen
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MOA Suppressor
External Link
TTD: D05AHK
 Compound Name Pifithrin-alpha Terminated [18]
Synonyms
P53 inhibitor, Univ of Illinois; PFT-alpha; PFT-beta; Pifithrin compounds, Quark; Pifithrin-beta
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MOA Inhibitor
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CID: 9929138
TTD: D02NYK
 Compound Name TAR-1 Terminated [19]
Synonyms
P53 protein modulator (single-chain antibody fragment, cancer), Ramot/Champions
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External Link
TTD: D0LG1K
 Compound Name 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine Investigative [20]
Synonyms
PhiKan 083; [(9-ethyl-9H-carbazol-3-yl)methyl](methyl)amine; EN300-43214; 880813-36-5; AC1NGDXR; PhiKan-083; BAS 13152361; PhiKan-083 Hydrochloride; CHEMBL1235116; SCHEMBL20181195; AC1Q3123; ZINC3888893; STK511393; IMED102848735; AKOS000284549; MCULE-1841863738; DB08363; NCGC00379107-01; NCGC00379107-02; ST072505; [(9-ethylcarbazol-3-yl)methyl]methylamine; HY-108637; CS-0029368; [(9-ethylcarbazol-3-yl)methyl](methyl)amine; 1-(9-ethylcarbazol-3-yl)-N-methylmethanamine
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MOA Inhibitor
External Link
CID: 4722579
TTD: D08PLU
DrugBank: DB08363
 Compound Name NUTLIN-3 Investigative [21]
Synonyms
548472-68-0; 890090-75-2; nutlin-3A; nutlin 3; (+/-)-Nutlin3; CHEMBL211045; Nutlin 3(Random Configuration); MDM2 Antagonist, Nutlin-3, Racemic; 4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-({4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
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MOA Inhibitor
External Link
CID: 216345
TTD: D01QKK
 Compound Name NU-8231 Investigative [22]
Synonyms
SCHEMBL2454464; CHEMBL360944
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MOA Inhibitor
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CID: 11648438
TTD: D0F1SN
 Compound Name OPI-1002 Phase 2 [23]
External Link
TTD: D02CKH
 Compound Name Cenersen Phase 2 [23]
External Link
CID: 56841947
TTD: D0K4VW
 Compound Name AHL Investigative [23]
Synonyms
AHLi-11; SiRNA therapeutics (hearing loss), Quark; P53 gene-silencing siRNA (hearing loss), Quark
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External Link
TTD: D0T8EL
 Compound Name PC14586 Phase 1/2 [23]
External Link
TTD: D53CGK
WD repeat-containing protein 5 (WDR5) 1 Compound(s) Regulating the Target Click to Show/Hide the Full List
 Compound Name OICR-9429 Investigative [24]
Synonyms
1801787-56-3; OICR9429; CHEMBL3798846; N-(4-(4-Methylpiperazin-1-Yl)-3'-(Morpholinomethyl)-[1,1'-Biphenyl]-3-Yl)-6-Oxo-4-(Trifluoromethyl)-1,6-Dihydropyridine-3-Carboxamide; N-[2-(4-methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide; GTPL8231; OICR 9429; MolPort-039-101-294; EX-A2417; BCP18185; BDBM50164794; s7833; AKOS025147341; ZINC231558892; SB19642; CS-5776; NCGC00371263-02; AK468854; HY-16993; J3.618.049H
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MOA Antagonist
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CID: 91623360
TTD: D0XI3W
2C12: Liver cancer 49 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name 90Y-loaded resin microspheres Approved [25]
External Link
TTD: DGWE36
 Compound Name Thymalfasin Phase 2 [26]
Synonyms
Zadaxin; 62304-98-7; Thymosin alpha1; Thymosin alpha 1; Thymosin alpha1 (ox); Thymosin alpha1 (human); Thymalfasin [USAN:INN]; UNII-W0B22ISQ1C; Thymosin-alpha-1; 69440-99-9; Thymosin alpha1 (cattle); C129H215N33O55; W0B22ISQ1C; Zadaxin (TN); Thymalfasin alfa 1
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CID: 16130571
TTD: D0I5KX
 Compound Name Ferumoxides Approved [27]
Synonyms
AMI-25; 119683-68-0; Feridex; Feridex IV; Superparamagnetic iron oxide; UNII-G6N3J05W84; Ferumoxides [USAN:USP:BAN]; CCRIS 6722; HSDB 8072; AC1O5DID; G6N3J05W84; iron(2+); iron(3+); Iron oxide crystal is inverse spinel (X-ray data); Fe(II) and Fe(III) are present (Mossbauer Spectroscopy; Physical form is a colloidal particle of nonstoichiometric
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CID: 6432052
TTD: D08QAC
DrugBank: DB06215
 Compound Name DTI-015 Approved [28]
Synonyms
Carmustine; 154-93-8; 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Carmustin; Nitrumon; Carmubris; Gliadel; BiCNU; Bi CNU; Carmustinum; Bischlorethylnitrosurea; Bischlorethylnitrosourea; Carmustina; Becenun; Becenum; Bischloroethyl nitrosourea; N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA; Bis(2-chloroethyl)nitrosourea; Urea, N,N'-bis(2-chloroethyl)-N-nitroso-; Gliadel Wafer; FDA 0345; Bischloroethylnitrosourea; SRI 1720; 1,3-Bis(2-chloroethyl)nitrosourea; BiCNU (TN); Carmustinum [INN-Latin]; Carmustina [INN-Spanish]; DTI 015; NCI-C04773; SK; Injectable carmustine, Direct Therapeutics
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External Link
CID: 2578
TTD: D01OXI
DrugBank: DB00262
 Compound Name Nofazinlimab Phase 3 [29]
Synonyms
CS1003; EQ176
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External Link
TTD: DX9GT7
 Compound Name PV-10 Phase 3 [9]
Synonyms
632-69-9; Rose bengal sodium; Rose bengal disodium salt; R105 sodium; Rose-bengal (131 I) natrium; Food Red No 105, sodium salt; EINECS 211-183-3; Food Red Color No 105, sodium salt; Sel disodique de rose bengale iodee (131 I); Rose bengale (131 I) sodique [INN-French]; Rosa bengala sodica (131 I) [INN-Spanish]; Roseum bengalense (131 I) natricum [INN-Latin]; 2,4,5,7-Tetraido(m,p,o',m')tetrachlorofluorescein, disodium salt; Fluorescein, 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-, disodium salt; Disodium
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External Link
CID: 69438
TTD: D0L2VT
 Compound Name Brivanib Phase 3 [30]
Synonyms
649735-46-6; BMS-540215; Brivanib (BMS-540215); BMS 540215; UNII-DDU33B674I; Brivanib [USAN]; BMS540215; DDU33B674I; CHEMBL377300; (2R)-1-[4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]propanol; Brivanib (USAN); (2R)-1-[4-[(4-FLUORO-2-METHYL-1H-INDOL-5-YL)OXY]-5-METHYL-PYRROLO[2,1-F][1,2,4]TRIAZIN-6-YL]OXYPROPAN-2-OL; (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
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External Link
CID: 11234052
TTD: D0HS5V
DrugBank: DB11958
 Compound Name JX-594 Phase 3 [31]
Synonyms
Pexastimogene devacirepvec
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External Link
TTD: D0HB0V
 Compound Name ABH001 Phase 3 [32]
External Link
TTD: D05LPP
 Compound Name MTC-DOX Phase 2/3 [33]
Synonyms
MTC-doxorubicin
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External Link
TTD: D0W9AI
 Compound Name KD018 Phase 2 [34]
External Link
TTD: D0NB9T
 Compound Name Doxorubicin-eluting beads Phase 2 [35]
Synonyms
DC Bead (TN)
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External Link
TTD: D0M5CD
 Compound Name 32-P BioSilicon Phase 2 [36]
Synonyms
BrachySil
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External Link
TTD: D0M1YS
 Compound Name Cixutumumab Phase 2 [37]
Synonyms
LY3012217
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External Link
TTD: D0E5DP
 Compound Name [131I]-Metuximab Phase 2 [38]
External Link
TTD: D0E5BW
 Compound Name Darinaparsin Phase 2 [39]
Synonyms
ZIO-101
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External Link
CID: 11683005
TTD: D03ZME
DrugBank: DB06179
 Compound Name Tigatuzumab Phase 2 [40]
External Link
TTD: D03LTO
 Compound Name CMC-001 Phase 2 [41]
Synonyms
Manganese-based MRI contrast agent (liver tumor imaging), CMC Contrast
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External Link
TTD: D00WMJ
 Compound Name OBP-301 Phase 1/2 [42]
External Link
TTD: D0D8ZK
 Compound Name MBO7133 Phase 1/2 [43]
External Link
TTD: D0C3MW
 Compound Name INCB62079 Phase 1/2 [9]
External Link
TTD: D0BE8H
 Compound Name NV-1020 Phase 1/2 [44]
External Link
TTD: D0B6EA
 Compound Name DCVax-Liver Phase 1/2 [45]
Synonyms
Dendritic cell-based immunotherapy (liver cancer), Northwest Biotherapeutics
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External Link
TTD: D00ESH
 Compound Name SRF388 Phase 1 [46]
External Link
TTD: DLY89F
 Compound Name ET140202 Phase 1 [47]
External Link
TTD: D4K2OF
 Compound Name ADP-A2AFP Phase 1 [48]
External Link
TTD: D31ORV
 Compound Name SM04755 Phase 1 [49]
External Link
TTD: D0P5XM
 Compound Name Anti-CEA CAR-T therapy Phase 1 [9]
External Link
TTD: D0OP1L
 Compound Name PI-166 Phase 1 [50]
External Link
TTD: D0J2YR
 Compound Name CRS-100 Phase 1 [51]
External Link
TTD: D0B4DL
 Compound Name Autologous ET1402L1-CART cells Phase 1 [52]
External Link
TTD: D09TGO
 Compound Name Anti-CD133-CAR vector-transduced T cells Phase 1 [53]
External Link
TTD: D09HRH
 Compound Name MRX34 Phase 1 [54]
External Link
TTD: D08SJY
 Compound Name ALN-VSP Phase 1 [55]
External Link
TTD: D08JMI
 Compound Name EPCAM-targeted CAR-T cells Clinical trial [56]
External Link
TTD: D0T8DD
 Compound Name ADI Discontinued in Phase 3 [57]
Synonyms
Arginine deiminase
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External Link
CID: 46906074
TTD: D0O4EV
 Compound Name GN-1140 Discontinued in Phase 2 [58]
External Link
TTD: D0V4CL
 Compound Name OGT-719 Discontinued in Phase 2 [59]
Synonyms
OGS-719
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External Link
CID: 9838997
TTD: D0C2CH
 Compound Name AFP-Scan Discontinued in Phase 2 [60]
External Link
TTD: D08CCC
 Compound Name SR1078 Preclinical [61]
Synonyms
1246525-60-9; SR 1078; SR-1078; N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide; CHEMBL3094387; N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-4-(trifluoromethyl)benzamide; N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide; SCHEMBL4880524; C17H10F9NO2; DTXSID30591895; BCP09203; EX-A2215; 4063AH; BDBM50444350; s5775; ZINC98052696; AKOS024458390; CS-1045; NCGC00379222-02; AK547149; AS-55921; HY-14422; W-5797; SR-03000001078; SR-03000001078-1; SR-03000001078-2
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External Link
CID: 17980288
TTD: D9D6QN
 Compound Name Occlusin Preclinical [62]
Synonyms
Occlusin 50 Injection; Occlusin 500 injection
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TTD: D00INM
 Compound Name HRC-201 Terminated [63]
Synonyms
Hemoglobin-imaging conjugate (HepSelect), Hemosol
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External Link
TTD: D09ZCH
 Compound Name 1,2,3,4,5,6-hexabromocyclohexane Investigative [64]
Synonyms
1837-91-8; Benzene hexabromide; Cyclohexane, 1,2,3,4,5,6-hexabromo-; Hexabromocyclohexane; JAK2 Inhibitor II; ACMC-1BQJT; SCHEMBL459442; trans-alpha-Benzene hexabromide; CHEMBL444236; DTXSID4052687; CHEBI:93940; NSC7908; HMS3268H22; HMS3413C10; HMS3677C10; NSC-7908; ZINC1586309; ANW-23174; MFCD00059127; s5902; Cyclohexane,2,3,4,5,6-hexabromo-; AKOS015836040; 1,2,3,4,5,6-Hexabromo-cyclohexane; 1,2,3,4,5,6-Hexabromocyclohexane #; NCGC00092358-01; NCGC00092358-02; 1,2,3,4,5,6-hexakis(bromanyl)cyclohexane; A4510; FT-0633875; JAK2 Inhibitor II - CAS 1837-91-8; 1,2,3,4,5,6-Hexabromocyclohexane;NSC7908; A812818; 1,2,3,4,5,6-Hexabrom-cyclohexan (I(2)-Form); J-011778; 1,2,3,4,5,6-Hexabromocyclohexane, >=98% (HPLC); BRD-K06817181-001-01-5; Q27165694
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CID: 74603
TTD: DLW69V
 Compound Name STP-322 Investigative [65]
Synonyms
Multi-targeted siRNA therapeutic cocktail (nanoparticle, liver tumor), Sirnaomics
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External Link
TTD: D0R8KF
 Compound Name AMB-8LK Investigative [65]
Synonyms
Cancer therapy (monoclonal antibody), MAT Biopharma; Y90 anti-ferritin monoclonal antibody (cancer), MAT Biopharma; Yttrium-90 anti-ferritin mAb (cancer), MAT Biopharma; Yttrium-90 anti-ferritin mAb (Hodgkin's disease/pancreatic/liver cancer), MAT Biopharma; 90Y-AMB8LK mAb (cancer), MAT Biopharma; 90Y-AMB8LK monoclonal antibody (cancer), MAT Biopharma; 90Y-labelled anti-ferritin monoclonal antibody (cancer), MAT Biopharma
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TTD: D0P2MD
 Compound Name MiR-34a mimics Investigative [65]
Synonyms
MiR-34a mimics (liver cancer)
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External Link
TTD: D0M9TD
 Compound Name P53 fusion protein Investigative [65]
Synonyms
P53 fusion protein (pancreatic/liver cancer)
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External Link
TTD: D06WLG
 Compound Name OP-05 Investigative [65]
Synonyms
OP-05 program (prodrug, liver tumor); OP-05 program (prodrug, liver tumor), Onco-Pharmakon
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TTD: D02OIP
 Compound Name GR-DD1 Investigative [65]
Synonyms
Cytotoxin (hepatic metastasis), ERYtech
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TTD: D00QFV
References
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