m6A-centered Crosstalk Information

Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT02094
 [1]
m6A modification TET1 TET1 METTL3 Methylation : m6A sites Direct Inhibition DNA methylation TET1 STAT3
m6A Modification:
m6A Regulator Methyltransferase-like 3 (METTL3) WRITER
 Regulator Info 
m6A Target Methylcytosine dioxygenase TET1 (TET1)
 Targert Gene 
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type DNA methylation (DNAMeth)
Epigenetic Regulator Methylcytosine dioxygenase TET1 (TET1) ERASER View Details
Regulated Target Signal transducer and activator of transcription 3 (STAT3) View Details
Crosstalk Relationship m6A  →  DNA methylation Inhibition
Crosstalk Mechanism m6A modification directly impacts DNA methylation through modulating the expression level of DNA methyltransferases or demethylases.
Crosstalk Summary Overexpressing METTL3 reversed a loss of m6A in Tet1 mRNA and blocked the CFA-induced increase of Methylcytosine dioxygenase TET1 (TET1) in the spinal cord, resulting in the attenuation of pain behavior, and acted as an upstream regulator of Signal transducer and activator of transcription 3 (STAT3). Furthermore, the decreased level of spinal YT521-B homology domain family protein 2 (YTHDF2), an RNA m6A reader, stabilized upregulation of spinal TET1 because of the reduction of Tet1 mRNA decay by the binding to m6A in Tet1 mRNA in the spinal cord after CFA.
Responsed Disease Inflammatory pain ICD-11: MG30.42
 Disease Info 
In-vivo Model Three strains' mice were used: Shanghai populations of Kunming mice, Tet1fl/fl C57BL/6 mice, and Mettl3fl/fl C57BL/6 mice (Cyagen Biosciences, Guangzhou, China). Pups were kept with their dams after born and weaned at postnatal day 21, then group housed by sex with 4 to 5 mice per cage. The genotype of each mouse was determined by the genomic DNA extracted from tail tip tissue. All mice used in the experiment were 6 8-week-old male mice, maintained at 23 ±3°C with 35% w10% relative humidity, on a 12 hours light/dark cycle (lights on 6:00, lights off 18:00), and libitum accessed to food and water.
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
Signal transducer and activator of transcription 3 (STAT3) 74 Compound(s) Regulating the Target Click to Show/Hide the Full List
 Compound Name Acitretin Approved [2]
Synonyms
Acitretina; Acitretine; Acitretinum; Etretin; Isoacitretin; Isoetretin; Neotigason; Soriatane; TMMP; Acitretina [Spanish]; Acitretine [French]; Acitretinum [Latin]; Retinoid etretin; U0279; Ro 10-1670; Ro 13-7652; Soriatane (TN); Soriatane, Acitretin; Acitretin (USAN/INN); Acitretin [USAN:INN:BAN]; All-trans-Acitretin; Ro 10-1670/000; Ro-10-1670; Ro-13-7652; Ro-10-1670/000; All-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid; (2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid; (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid; (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; 13-cis-Acitretin; 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
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MOA Inhibitor
External Link
CID: 5284513
TTD: D05QDC
DrugBank: DB00459
 Compound Name Napabucasin Phase 3 [3]
Synonyms
83280-65-3; UNII-Z1HHM49K7O; 2-acetylnaphtho[2,3-b]furan-4,9-dione; Z1HHM49K7O; 2-Acetylnaphtho(2,3-b)furan-4,9-dione; 2-Acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione; Napabucasin [USAN:INN]; Napabucasin (BBI608); 2-Acetylfuranonaphthoquinone; CHEMBL64130; Napabucasin (JAN/USAN/INN); SCHEMBL1883845; Napabucasin - BBI 608/ FNQ; 2-Acetylfuro-1,4-naphthoquinone; DPHUWDIXHNQOSY-UHFFFAOYSA-N; MolPort-039-101-321; EX-A1314; ZINC13306865; s7977; AKOS027470201; DB12155; CS-1747; ACN-053294; HY-13919
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MOA Inhibitor
Activity EC50 = 1900 nM
External Link
CID: 10331844
TTD: D01IGZ
DrugBank: DB12155
 Compound Name Golotimod Phase 2 [4]
Synonyms
229305-39-9; SCV-07; gamma-D-Glu-L-trp; SCV07; gamma-D-Glutamyl-L-tryptophan; SCV 07; UNII-637C487Y09; 637C487Y09; (R)-2-Amino-5-(((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoic acid; Golotimod [USAN:INN]; (2R)-2-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid; (2R)-2-Amino-5-(((1S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoic acid; Golotimod (USAN/INN); GAMMA-D-GLU-TRP-OH; H-D-Glu(L-Trp-OH)-OH; SCHEMBL727944; (gamma-glutamyl-L-tryptophan); CHEMBL2103812; Golotimod (oral); Golotimod (oral), SciClone/Verta; SCV-07 (oral, tuberculosis), SciClone/Verta
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MOA Inhibitor
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CID: 6992140
TTD: D02MRN
DrugBank: DB05475
 Compound Name Atiprimod Phase 1/2 [5]
Synonyms
Atiprimod [INN]; SKF 106615; SKF-106615; N,N-Diethyl-8,8-dipropyl-2-azaspiro(4.5)decane-2-propanamine; 3-(8,8-dipropyl-3-azaspiro[4.5]decan-3-yl)-N,N-diethylpropan-1-amine
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MOA Inhibitor
External Link
CID: 129869
TTD: D0D9LJ
DrugBank: DB05513
 Compound Name OPB-31121 Phase 1/2 [6]
MOA Inhibitor
External Link
TTD: D0E7IM
 Compound Name IMX-110 Phase 1/2 [3]
MOA Inhibitor
External Link
TTD: D0H7DM
 Compound Name GLG-801 Phase 1/2 [3]
MOA Inhibitor
External Link
TTD: D0P7IL
 Compound Name WP-1066 Phase 1/2 [3]
Synonyms
WP1066; 857064-38-1; (S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide; WP 1066; UNII-63V8AIE65T; 63V8AIE65T; AK-99218; C17H14BrN3O; (E)-3-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide; MLS006010178; SCHEMBL1315826; QCR-16; SCHEMBL1315831; GTPL7972; CHEMBL1923234; EX-A760; AOB1497; DTXSID50235007; MolPort-044-723-708; MolPort-023-219-149; ZINC13983221; AKOS016007983; WP1066/WP-1066; CS-2736; DB12679; 2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-((1S)-1-phenylethyl)-, (2E)-; HY-15312
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MOA Inhibitor
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CID: 11210478
TTD: D0IV4C
DrugBank: DB12679
 Compound Name NT219 Phase 1/2 [7]
Synonyms
UNII-K1WT1A1UP5; K1WT1A1UP5; 1198078-60-2; (E)-3-(2-Bromo-3,4-dihydroxyphenyl)-N-(3,4,5-trihydroxybenzyl)prop-2-enethioamide; CHEMBL3679680; SCHEMBL12659248; BDBM101913; NT-219; US8536227, 5; 2-Propenethioamide, 3-(2-bromo-3,4-dihydroxyphenyl)-N-((3,4,5-trihydroxyphenyl)methyl)-; 2-Propenethioamide, 3-(2-bromo-3,4-dihydroxyphenyl)-N-((3,4,5-trihydroxyphenyl)methyl)-, (2E)-
    Click to Show/Hide
MOA Inhibitor
External Link
CID: 135914977
TTD: DUI59O
 Compound Name OPB-51602 Phase 1 [8]
MOA Inhibitor
External Link
TTD: D01FFC
 Compound Name TAK-114 Phase 1 [9]
MOA Modulator
External Link
TTD: D01RCM
 Compound Name WP1220 Phase 1 [10]
Synonyms
mol4239; MOL-4239; PTN9LJL6PY; UNII-PTN9LJL6PY; WP-1220; 2,4-Pentadienamide, 5-(6-bromo-2-pyridinyl)-2-cyano-N-((1S)-1-phenylethyl)-, (2E,4E)-; 1204306-34-2; SCHEMBL862248; SCHEMBL1316581; CHEMBL4594434; (2E,4E)-5-(6-Bromo-2-pyridinyl)-2-cyano-N-((1S)-1-phenylethyl)-2,4-pentadienamide; (2E,4E)-5-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]penta-2,4-dienamide
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MOA Inhibitor
External Link
CID: 44554865
TTD: D3U8YR
 Compound Name DSP-0337 Phase 1 [11]
MOA Inhibitor
External Link
TTD: DLJN17
 Compound Name OPB-111077 Phase 1 [12]
MOA Inhibitor
External Link
TTD: DN81JB
 Compound Name Quinoline carboxamide derivative 2 Patented [13]
Synonyms
PMID26394986-Compound-29
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MOA Inhibitor
External Link
CID: 67206397
TTD: D00FUZ
 Compound Name Peptidomimetic analog 3 Patented [13]
Synonyms
PMID26394986-Compound-5
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MOA Inhibitor
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CID: 24772856
TTD: D02CJU
 Compound Name PMID26394986-Compound-11 Patented [13]
MOA Inhibitor
External Link
CID: 341
TTD: D02ILH
 Compound Name Flavonoid derivative 5 Patented [13]
Synonyms
PMID26394986-Compound-49
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MOA Inhibitor
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TTD: D02KDA
 Compound Name Salicylic acid derivative 6 Patented [13]
Synonyms
PMID26394986-Compound-18
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MOA Inhibitor
Activity Ki = 10000 nM
External Link
CID: 72550504
TTD: D03ARS
 Compound Name Gold-complexed thiosaccharide derivative 2 Patented [13]
Synonyms
PMID26394986-Compound-67
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MOA Inhibitor
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CID: 56946870
TTD: D03HEP
 Compound Name Peptidomimetic analog 1 Patented [13]
Synonyms
PMID26394986-Compound-3
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MOA Inhibitor
Activity IC50 = 125 nM
External Link
TTD: D03VMP
 Compound Name Quinoline carboxamide derivative 1 Patented [13]
Synonyms
PMID26394986-Compound-28
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MOA Inhibitor
Activity IC50 = 74000 nM
External Link
CID: 4253236
TTD: D03XAK
 Compound Name Salicylic acid derivative 4 Patented [13]
Synonyms
PMID26394986-Compound-16
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MOA Inhibitor
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CID: 72545583
TTD: D04ANB
 Compound Name PMID26394986-Compound-12 Patented [13]
MOA Inhibitor
External Link
CID: 237973
TTD: D04GVY
 Compound Name PMID26394986-Compound-21 Patented [13]
MOA Inhibitor
Activity IC50 = 15000 nM
External Link
CID: 73672447
TTD: D06RBL
 Compound Name Salicylic acid derivative 5 Patented [13]
Synonyms
PMID26394986-Compound-17
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MOA Inhibitor
Activity Kd = 300 nM
External Link
CID: 72188643
TTD: D08EID
 Compound Name PMID26394986-Compound-20 Patented [13]
MOA Inhibitor
Activity IC50 = 45000 nM
External Link
CID: 76336555
TTD: D08ETA
 Compound Name PMID26394986-Compound-43 Patented [13]
MOA Inhibitor
External Link
CID: 46911017
TTD: D08SEP
 Compound Name PMID26394986-Compound-50 Patented [13]
MOA Inhibitor
External Link
CID: 9881541
TTD: D09BOL
 Compound Name PMID26394986-Compound-44 Patented [13]
MOA Inhibitor
External Link
CID: 65064
TTD: D09CKU
DrugBank: DB12116
 Compound Name PMID26394986-Compound-51 Patented [13]
MOA Inhibitor
External Link
CID: 118707758
TTD: D09SYX
 Compound Name Salicylic acid derivative 3 Patented [13]
Synonyms
PMID26394986-Compound-14a
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MOA Inhibitor
Activity IC50 = 12800 nM
External Link
CID: 73333953
TTD: D09ZCV
 Compound Name Quinoline carboxamide derivative 3 Patented [13]
Synonyms
PMID26394986-Compound-30
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MOA Inhibitor
External Link
CID: 67204713
TTD: D0D8RR
 Compound Name Pyrazole derivative 62 Patented [13]
Synonyms
PMID26394986-Compound-23
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MOA Inhibitor
External Link
CID: 72543768
TTD: D0DC3S
 Compound Name Pyrazole derivative 63 Patented [13]
Synonyms
PMID26394986-Compound-24
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MOA Inhibitor
External Link
CID: 72705159
TTD: D0ET3L
 Compound Name Flavonoid derivative 3 Patented [13]
Synonyms
PMID26394986-Compound-47
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MOA Inhibitor
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CID: 5281612
TTD: D0EV5U
DrugBank: DB11259
 Compound Name Peptide analog 7 Patented [13]
Synonyms
PMID26394986-Compound-1
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MOA Inhibitor
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TTD: D0EW9W
 Compound Name Salicylic acid derivative 1 Patented [13]
Synonyms
PMID26394986-Compound-13a
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MOA Inhibitor
Activity IC50 = 2800 nM
External Link
CID: 68075823
TTD: D0EX9O
 Compound Name Gold-complexed thiosaccharide derivative 1 Patented [13]
Synonyms
PMID26394986-Compound-66
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MOA Inhibitor
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TTD: D0FH4G
 Compound Name Gold-complexed thiosaccharide derivative 3 Patented [13]
Synonyms
PMID26394986-Compound-68
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MOA Inhibitor
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TTD: D0J1US
 Compound Name PMID26394986-Compound-22 Patented [13]
MOA Inhibitor
External Link
CID: 2662
TTD: D0KP0U
DrugBank: DB00482
 Compound Name Pyrazole derivative 65 Patented [13]
Synonyms
PMID26394986-Compound-26
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MOA Inhibitor
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CID: 72705348
TTD: D0M5AR
 Compound Name Pyrazole derivative 64 Patented [13]
Synonyms
PMID26394986-Compound-25
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MOA Inhibitor
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CID: 72705347
TTD: D0M8OV
 Compound Name PMID26394986-Compound-42 Patented [13]
MOA Inhibitor
External Link
CID: 9799188
TTD: D0MA8T
 Compound Name Peptidomimetic analog 2 Patented [13]
Synonyms
PMID26394986-Compound-4
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MOA Inhibitor
Activity IC50 = 17 nM
External Link
TTD: D0QR1I
 Compound Name Pyrazole derivative 66 Patented [13]
Synonyms
PMID26394986-Compound-27
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MOA Inhibitor
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TTD: D0S0UL
 Compound Name PMID26394986-Compound-52 Patented [13]
MOA Inhibitor
External Link
TTD: D0T1GB
 Compound Name Salicylic acid derivative 2 Patented [13]
Synonyms
PMID26394986-Compound-14
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MOA Inhibitor
Activity IC50 = 19000 nM
External Link
CID: 53388144
TTD: D0U7LL
 Compound Name Salicylic acid derivative 7 Patented [13]
Synonyms
PMID26394986-Compound-19
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MOA Inhibitor
Activity Ki = 10000 nM
External Link
CID: 72545832
TTD: D0V3PA
 Compound Name PMID26394986-Compound-53 Patented [13]
MOA Inhibitor
External Link
CID: 25226944
TTD: D0V7HS
 Compound Name Flavonoid derivative 1 Patented [13]
Synonyms
PMID26394986-Compound-45
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MOA Inhibitor
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CID: 5280445
TTD: D0V7NH
DrugBank: DB15584
 Compound Name PMID26394986-Compound-54 Patented [13]
MOA Inhibitor
External Link
CID: 25226945
TTD: D0WW1Z
 Compound Name Peptidomimetic analog 4 Patented [13]
Synonyms
PMID26394986-Compound-6
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MOA Inhibitor
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TTD: D0X6QQ
 Compound Name PMID26394986-Compound-13 Patented [13]
MOA Inhibitor
Activity IC50 = 35000 nM
External Link
CID: 24767791
TTD: D0Y0OQ
 Compound Name Tri-substituted purine derivative 1 Patented [13]
Synonyms
PMID26394986-Compound-9
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MOA Inhibitor
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CID: 71770709
TTD: D0Y2PO
 Compound Name Flavonoid derivative 4 Patented [13]
Synonyms
PMID26394986-Compound-48
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MOA Inhibitor
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CID: 5280343
TTD: D0Y3DN
DrugBank: DB04216
 Compound Name Flavonoid derivative 2 Patented [13]
Synonyms
PMID26394986-Compound-46
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MOA Inhibitor
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TTD: D0Z8BD
 Compound Name PMID26394986-Compound-Figure16 Patented [13]
MOA Inhibitor
Activity IC50 < 150 nM
External Link
TTD: D0ZQ8T
 Compound Name PMID26394986-Compound-Figure17 Patented [13]
MOA Inhibitor
External Link
TTD: D0ZS8Q
 Compound Name Oxazole derivative 1 Patented [13]
Synonyms
PMID26394986-Compound-8
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MOA Inhibitor
Activity IC50 = 79000 nM
External Link
CID: 24768190
TTD: D0EZ6V
 Compound Name Curcumin analog 2 Patented [13]
Synonyms
PMID26394986-Compound-33
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MOA Inhibitor
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CID: 68019246
TTD: D0IC8O
 Compound Name Curcumin analog 1 Patented [13]
Synonyms
PMID26394986-Compound-32
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MOA Inhibitor
Activity Kd = 172 nM
External Link
CID: 11487078
TTD: D0WD1Z
 Compound Name Peptidomimetic analog 5 Patented [13]
Synonyms
PMID26394986-Compound-7
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MOA Inhibitor
Activity IC50 = 310000 nM
External Link
CID: 9870708
TTD: D0XQ3F
 Compound Name Platinum IV complexe 1 Patented [13]
Synonyms
PMID26394986-Compound-69
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MOA Inhibitor
Activity IC50 = 1400 nM
External Link
TTD: D01BVU
 Compound Name PMID26394986-Compound-10 Patented [13]
MOA Inhibitor
Activity IC50 = 86000 nM
External Link
CID: 252682
TTD: D0TU0X
 Compound Name GNF-PF-1399 Investigative [14]
Synonyms
GNF-PF-2708; GNF-PF-4643
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MOA Inhibitor
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CID: 107464
TTD: D06PZK
 Compound Name ISIS-STAT3 Phase 1/2 [15]
External Link
TTD: D0B4MK
 Compound Name C188-9 Phase 1 [15]
Synonyms
QDCJDYWGYVPBDO-UHFFFAOYSA-N; UNII-KZ3DLD11RQ; KZ3DLD11RQ; AC1LQFBK; MLS006011646; SCHEMBL16394007; CHEMBL3392776; MolPort-000-644-242; N-(1B; ZINC1154831; AKOS001673470; MCULE-7568979350; NCGC00262829-02; SMR004703404; EU-0081697; AB00117290-01; C-188-9; N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)naphthalen-1-yl]-4-methoxybenzenesulfonamide; N-[4-hydroxy-3-(2-hydroxy-1-naphthyl)-1-naphthyl]-4-methoxy-1-benzenesulfonamide; Benzenesulfonamide, N-(1',2-dihydroxy(1,2'-binaphthalen)-4'-yl)-4-methoxy-; 432001-19-9
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CID: 1324494
TTD: D09CLC
 Compound Name ISIS 113187 Investigative [15]
External Link
TTD: D03MRO
 Compound Name ISIS 113176 Investigative [15]
External Link
TTD: D07XRC
 Compound Name ISIS 113209 Investigative [15]
External Link
TTD: D09YBP
 Compound Name ISIS 113210 Investigative [15]
External Link
TTD: D0E3ZU
 Compound Name ISIS 17148 Investigative [15]
External Link
TTD: D0O3DZ
 Compound Name ISIS 17152 Investigative [15]
External Link
TTD: D0W2FY
MG30: Chronic pain 293 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name Morphine Approved [16]
Synonyms
Avinza; Kadian; Morphine Sulfate; Depodur; Astramorph Pf; Duramorph Pf; Infumorph; Ms Contin; Oramorph Sr
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External Link
CID: 5288826
TTD: D0WE3O
DrugBank: DB00295
 Compound Name Ketoprofen Approved [17]
Synonyms
Actron; Alrheumat; Alrheumum; Alrheumun; Aneol; Capisten; Dexal; Epatec; Fastum; Kefenid; Ketoprofene; Ketoprofeno; Ketoprofenum; Ketopron; Ketoprophene; Lertus; Menamin; Meprofen; Orudis; Orugesic; Oruvail; Oscorel; Profenid; Toprec; Toprek; Benzoylhydratropic Acid; Orudis KT; K 1751; RP 19583; RP19583; RU 4733; Arthril (TN); Fastum (TN); Fastum Gel (TN); Iso-K; Keto (TN); Ketoflam (TN); Ketomex (TN); Ketonal (TN); Ketoprofenas (TN); Ketoprofene (TN); Ketoprofene [INN-French]; Ketoprofeno [INN-Spanish]; Ketoprofenum (TN); Ketoprofenum [INN-Latin]; Ketorin (TN); Ketospray (TN); Lasonil (TN); M-Benzoylhydratropic acid; Oki (TN); Orudis (TN); Oruvail (TN); RP-19583; Racemic-Ketoprofen; Zon (TN); Bi-Profnid (TN); RP, 19,583; Ketoprofen (JP15/USP/INN); Ketoprofen [USAN:INN:BAN:JAN]; Orudis, Oruvail, Ketoflam, Orudis KT, Ketoprofen; Acide (benzoyl-3-phenyl)-2-propionique; Acide (benzoyl-3-phenyl)-2-propionique [French]; L'Acide (benzoyl-3-phenyl)-2-propionique; (+-)-m-Benzoylhydratropic acid; 2-(3-Benzoylphenyl)propanoic acid; 2-(3-Benzoylphenyl)propionic acid; 2-(m-Benzoylphenyl)propionic acid; 2-[3-(benzoyl)phenyl]propanoic acid; 2-[3-(phenylcarbonyl)phenyl]propanoic acid; 2-[3-Benzoylphenyl]propionic acid; 3-Benzoylhydratropic acid
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CID: 3825
TTD: D0W9WF
DrugBank: DB01009
 Compound Name Strontium Chloride Sr-89 Approved [16]
Synonyms
Metastron
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External Link
CID: 5388879
TTD: D0R6HN
DrugBank: DB09498
 Compound Name Alpha 1-PI Withdrawn from market [18]
Synonyms
Ifenprodil; 23210-56-2; Vadilex; ifenprodil tartrate; Dilvax; Creocral; 4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol; Ifenprodil [INN:DCF]; RC 61-91; Ifenprodilum [INN-Latin]; UNII-R8OE3P6O5S; EINECS 245-491-4; R8OE3P6O5S; CHEMBL305187; 4-Benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol; 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propanol; 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol; NCGC00024643-03; IFENPRODIL HEMITARTRATE; alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine
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CID: 3689
TTD: D0I0DL
DrugBank: DB08954
 Compound Name Fentanyl Approved [19]
Synonyms
Fentanil; Phentanyl; Fentora; Sublimaze; Fentanila; Fentanest; Duragesic; Fentanylum; Durogesic; Sentonil; 437-38-7; Duragesic-100; IONSYS; Duragesic-25; Duragesic-75; Duragesic-50; Duragesic-12; Fentanyl-25; Fentanyl-75; Fentanyl-12; Fentanyl-50; Fentanylum [INN-Latin]; Fentanila [INN-Spanish]; Fentanyl-100; 1-Phenethyl-4-N-propionylanilinopiperidine; Matrifen; Sublimase; N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide; N-(1-Phenethyl-4-piperidyl)propionanilide; N-Phenethyl-4-(N-propionylanilino)piperidine; Fentanil [DCIT]; Subsys; Fentanyl-37; Fentanyl-62; Fentanyl-87; Abstral; Actiq; Lazanda; Onsolis; Fentanyl Citrate; Fentanyl Citrate Preservative Free; Sublimaze Preservative Free; fentanyl (transmucosal film, pain), Auxilium Pharmaceuticals
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CID: 3345
TTD: D0E1WI
DrugBank: DB00813
 Compound Name Phenylbutazone Approved [20]
Synonyms
Alindor; Alkabutazona; Alqoverin; Anerval; Anpuzone; Antadol; Anuspiramin; Arthrizon; Artizin; Artrizin; Artrizone; Artropan; Azdid; Azobutyl; Azolid; Benzone; Betazed; Bizolin; Bunetzone; Busone; Butacompren; Butacote; Butadion; Butadiona; Butadione; Butadionum; Butagesic; Butalgina; Butalidon; Butaluy; Butaphen; Butapirazol; Butapirazole; Butapyrazole; Butarecbon; Butartril; Butartrina; Butatron; Butazina; Butazolidin; Butazolidine; Butazona; Bute; Butidiona; Butone; Butoz; Butylpyrin; Buvetzone; Buzon;Chembutazone; Cotylbutazone; Digibutina; Diossidone; Diozol; Diphebuzol; Diphenylbutazone; Ecobutazone; Elmedal; Equipalazone; Equiphen; Eributazone; Esteve; Febuzina; Fenartil; Fenibutal; Fenibutasan; Fenibutazona; Fenibutol; Fenilbutazon; Fenilbutazona; Fenilbutazone; Fenilbutina; Fenilbutine; Fenilidina; Fenotone; Fenylbutazon; Flexazone; Intalbut; Intrabutazone; Intrazone; Ipsoflame; Kadol; Lingel; Malgesic; Mephabutazon; Mephabutazone; Merizone; Nadazone; Nadozone; Novophenyl; Phebuzin; Phebuzine; Phenbutazol; Phenbutazone; Phenopyrine; Phenylbutaz; Phenylbutazon; Phenylbutazonum; Phenyzene; Phenyzone; Praecirheumin; Pyrabutol; Pyrazolidin; Rectofasa; Reudo; Reudox; Reumasyl; Reumazin; Reumazol; Reumune; Reumuzol; Reupolar; Robizone; Rubatone; Scanbutazone; Schemergen; Schemergin; Shigrodin; Tazone; Tencodyne; Tetnor; Tevcodyne; Therazone; Ticinil; Todalgil; Uzone; Wescozone; Zolaphen; Zolidinum; Alka Butazolidin; Art rizin; Buta phen; Butyl pyrin; Equi bute; Exrheudon N; Fe nilbutine; Fenilbutazone [DCIT]; Phenyl butazone; Phenylbutazon [German]; Pirarreumol B; A 7514; Bizolin 200; G 13871; P 8386; P1686; P1Z; AZOLID (TN); Apo-Phenylbutazone; Butiwas-Simple; Component of Azolid-A; DA-192; Fenilbutazona [INN-Spanish]; G 13,871; Ia-But; Mepha-Butazon; Neo-zoline; Phenyl-Mobuzon; Phenylbutazonum [INN-Latin]; Robizon-V; Robizone-V; Usaf ge-15; VAC-10; B.T.Z; Phen-Buta-Vet; R-3-ZON; B.t.z.; Bute, Butazolidin, Butatron, Phenylbutazone; Phenylbutazone (JP15/USP/INN); Phenylbutazone [USAN:INN:BAN:JAN]; 1,2-Diphenyl-2,3-dioxo-4-N-butylpyrazoline; 1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine; 1,2-Diphenyl-4-butyl-3,5-dioxopyrazolidine; 1,2-Diphenyl-4-butyl-3,5-pyrazolidinedione; 1,2-diphenyl-3,5-dioxo-4-n-butylpyrazoline; 3,5-Dioxe-4 buty-1, diphenyl-pyrazolidine; 3,5-Dioxo-1,2-diphenyl-4-N-butylpyrazolidine; 3,5-Dioxo-1,2-diphenyl-4-n-butyl-pyrazolidin; 3,5-dioxo-4-butyl-1-diphenyl-pyrazolidine; 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE; 4-Butyl-1,2-diphenyl-3,5-dioxopyrazolidine; 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione; 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione; 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione
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CID: 4781
TTD: D07VHR
DrugBank: DB00812
 Compound Name Samarium Sm-153 Lexidronam Pentasodium Approved [16]
External Link
CID: 9810246
TTD: D04YHR
DrugBank: DB09509
 Compound Name Hydromorphone Approved [21]
Synonyms
Dihydromorphinone; Dimorphone; Idromorfone; Hydromorphon; Dihydromorfinon; Hydromorfona; Laudacon; DiMo; Hydromorphonum; 7,8-Dihydromorphinone; Novolaudon; Hidromorfona; Dilaudid; Dilaudid Oros; Hydromorfona [Spanish]; Dihydromorfinon [Czech]; 466-99-9; Hydromorphonum [INN-Latin]; Hidromorfona [INN-Spanish]; Palladone; 6-Deoxy-7,8-dihydro-6-oxomorphine; Morphinone, dihydro-; Idromorfone [DCIT]; Laudicon; Hydromorphone [INN:BAN]; Dilaudid-hp; 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one; Hydromorphone HCL; Dilaudid (TN); Hydromorphone (INN); Palladone (TN); Palladone SR (TN); Morphinan-6-one, 4,5alpha-epoxy-3-hydroxy-17-methyl-(8CI); (-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one; (-)-Hydromorphone; (5alpha)-3-hydroxy-17-methyl-4,5-epoxymorphinan-6-one; 3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one; 4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone; Hydromorphone prodrug
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CID: 5284570
TTD: D04JHN
DrugBank: DB00327
 Compound Name Ethanol Approved [22]
Synonyms
Aethanol; Aethylalkohol; Alcohol; Alcohols; Algrain; Alkohol; Anhydrol; EOH; EOX; EtOH; Etanol; Etanolo; Ethicap; Ethylalcohol; Ethylol; Hinetoless; Hydroxyethane; Jaysol; Methylcarbinol; QMHAIh; Sekundasprit; Spirit; Spirt; Synasol; Tecsol; Thanol; Absolute alcohol; Absolute ethanol; Aethanol [German]; Alcare Hand Degermer; Alcohol [USP]; Alcohol anhydrous; Alcohol dehydrated; Alcohol etilico; Alcool ethylique; Alcool etilico; Alkohol [German]; Alkoholu etylowego; Anhydrous alcohol; Anhydrous ethanol; Cologne Spirit; Colognespirits; Dehydrated alcohol; Dehydrated ethanol; Denatured alcohol; Denatured ethanol; Desinfektol EL; Distilled spirits; Etanolo [Italian]; Ethanol Absolute; Ethanol Absolute Bp; Ethanol Anhydrous; Ethanol Extra Pure; Ethanol Vapor; Ethanol [JAN]; Ethanol solution; Ethanolum anhydricum; Ethyl alc; Ethyl alcohol; Ethyl alcohol usp; Ethyl hydrate; Ethyl hydroxide; Ethylalcohol [Dutch]; Ethyloxy Group; Etylowy alkohol; Fermentation alcohol; Grain alcohol; HYDROXYETHYL GROUP; Infinity Pure; Jaysol S; Methylated spirit; Molasses alcohol; Oxydimethylene Group; Potato alcohol; Reagent Alcohol; SY Fresh M; Spirits of wine; Spiritus vini; Tecsol C; AHD 2000; Anhydrol PM 4085; CDA 19; E7148_ALDRICH; Esumiru WK 88; Ethanol 200 proof; IMS 99; LTBB002977; SDA 3A; Alcohol (USP); Alcohol, Absolute; Alcohol, Grain; Alcohol, anhydrous; Alcohol, dehydrated; Alcohol, diluted; Alcohol, ethyl; Alcohols, C30; CDA 19-200; Ethanol (9CI); Ethanol, undenatured; Ru-Tuss Expectorant; SDA 40-2; SDM No. 37; ALCOHOL 5% IN D5-W; Alcohols, C1-3; Alcohols, C6-9; (C6-C9)Alkyl alcohol; 1-Hydroxyethane; 100C.NPA
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CID: 702
TTD: D00AMQ
DrugBank: DB00898
 Compound Name Mirogabalin Phase 3 [21]
Synonyms
1138245-13-2; UNII-S7LK2KDM5U; DS-5565; S7LK2KDM5U; Bicyclo[3.2.0]hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, (1R,5S,6S)-; Bicyclo(3.2.0)hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, (1R,5S,6S)-; 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid; ((1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo(3.2.0)hept-3-en-6-yl)acetic acid; Mirogabalin [INN]; Mirogabalin [USAN:INN]; [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid; DS5565; DS 5565; GTPL8303
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CID: 59509752
TTD: D07VFD
DrugBank: DB11825
 Compound Name Dihydrocodeine Phase 4 [23]
Synonyms
Dihydrocodeine bitartrate; DF 118; Dihydrocodeine (oral); S-8115; Dihydrocodeine (oral), Shionogi; (-)-Dihydrocodeine
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CID: 5284543
TTD: D0T6RC
DrugBank: DB01551
 Compound Name GSK2696273 Preregistration [24]
External Link
TTD: D0F4QV
 Compound Name Egalet-002 Phase 3 [21]
External Link
TTD: D0R8FL
 Compound Name Fulranumab Phase 3 [25]
External Link
TTD: D0O1GS
 Compound Name Nabiximols Phase 3 [26]
Synonyms
Sativex; GW-1000; Cannador; Nabiximols [USAN]; GW1000; GW 1000; Tetrahydrocannabinol-cannabidiol combination; Cannabidiol mixture with Tetrahydrocannabinol; delta-9-Tetrahydrocannabinol and cannabidiol; Cannabidiol and delta-9-tetrahydrocarnabinol; GW-1000-02
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External Link
CID: 44148067
TTD: D0C5CE
 Compound Name Tanezumab Phase 3 [27]
External Link
TTD: D00BVS
 Compound Name CR-845 Phase 2 [21]
Synonyms
Kappa opioid agonist (intravenous, pain), Cara/Ferring; Kappa opioid agonist (oral, pain), Cara/Ferring; Kappa opioid agonist (subcutaneous, pain), Cara/Ferring; CR-845 (iv infusion, pain), Cara/Ferring; CR-845 (oral capsule, pain), Cara/Ferring; CR-845 (subcutaneous, pain), Cara/Ferring; FE-202845 (iv, pain), Cara/Ferring; FE-202845 (oral, pain), Cara/Ferring; FE-202845 (sc, pain), Cara/Ferring
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External Link
TTD: D08NJE
 Compound Name LY3556050 Phase 2 [28]
Synonyms
(1R,5S,6R)-N-{2-methyl-1-[(3-methylpyridin-2-yl)oxy]propan-2-yl}-3-azabicyclo[3.1.0]hexane-6-carboxamide; 1638588-92-7; AT36106; BDBM311911; EN300-1700347; LY3556050; SCHEMBL16252692; US10166214, Example 47; Z3071648657
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CID: 86294067
TTD: DXE53Z
 Compound Name A277 Phase 2 [29]
External Link
TTD: DDQH94
 Compound Name LY3526318 Phase 2 [30]
External Link
TTD: D40GBC
 Compound Name V120083 Phase 2 [21]
Synonyms
S120083
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TTD: D0X3JK
 Compound Name XEN-2174 Phase 2 [31]
External Link
TTD: D0U2XU
 Compound Name Dapansutrile Phase 2 [21]
Synonyms
54863-37-5; OLT1177; UNII-2Z03364G96; 2Z03364G96; Dapansutrile [INN]; Dapansutrile [USAN:INN]; Dapansutrile (USAN/INN); 3-Methylsulfonylpropionitrile; 3-methanesulfonylpropanenitrile; 3-methylsulphonyl-propionitrile; SCHEMBL9934796; CHEMBL3989943; LQFRYKBDZNPJSW-UHFFFAOYSA-N; MolPort-008-545-498; ZINC32005410; Propanenitrile, 3-(methylsulfonyl)-; AKOS010140086; D10920; Z2719319073
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CID: 12714644
TTD: D0TH5H
 Compound Name Flupirtine Phase 2 [32]
Synonyms
56995-20-1; Flupirtine [INN:BAN]; Flupirtinum [INN-Latin]; Flupirtino [INN-Spanish]; UNII-MOH3ET196H; C15H17FN4O2; EINECS 260-503-8; MOH3ET196H; JUUFBMODXQKSTD-UHFFFAOYSA-N; ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate; D 9998; flupirtin maleate; ethyl 2-amino-6-(4-fluorobenzylamino)pyridin-3-ylcarbamate; Flupirtinum; Flupirtino; MLS002153180; Carbamic acid, (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)-, ethyl ester; NCGC00015451-03; SMR001230672; Flupirtin; Carbamic acid, [2-ami
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CID: 53276
TTD: D0SD9V
DrugBank: DB06623
 Compound Name ABT-652 Phase 2 [33]
External Link
TTD: D0S5BV
 Compound Name BMS-690514 Phase 2 [34]
Synonyms
BMS 690514; BMS690514
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CID: 11349170
TTD: D0R6UV
DrugBank: DB11665
 Compound Name PF-05089771 Phase 2 [35]
Synonyms
Nav1.7 blockers (pain), Pfizer; SCN9A blockers (pain), Pfizer/Icagen/Birkbeck; Voltage-gated sodium channel 1.7 blockers (pain), Pfizer
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External Link
CID: 46840946
TTD: D0O7QA
DrugBank: DB14856
 Compound Name EB-001 Phase 2 [21]
External Link
TTD: D0O1VU
 Compound Name Omnitram Phase 2 [21]
External Link
TTD: D0KZ3Q
 Compound Name NP-2 gene therapy Phase 2 [36]
External Link
TTD: D06ZQL
 Compound Name PF-06372865 Phase 2 [37]
External Link
CID: 76287260
TTD: D06TQR
 Compound Name Resiniferatoxin Phase 1 [21]
Synonyms
Reciniferatoxin; UNII-A5O6P1UL4I; A5O6P1UL4I; 57444-62-9; RTX; [3H]resiniferatoxin; 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)daphnetoxin 20-(3-hydroxy-5-methoxybenzeneacetate); CHEMBL448382; resinferatoxin; Benzeneacetic acid, 4-hydroxy-3-methoxy-, ((2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno(5,4-e)-1,3-benzodioxol-5-yl)methyl ester; Resiniferatoxin(RTX); CHEMBL17976
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CID: 5702546
TTD: D05XJW
DrugBank: DB06515
 Compound Name REL-1015 Phase 2 [21]
External Link
TTD: D03RYJ
 Compound Name Neramexane Phase 2 [38]
Synonyms
Neramexane [INN]; Mrz 2579; MRZ 2-579; 1,3,3,5,5-Pentamethylcyclohexanamine; 1,3,3,5,5-pentamethylcyclohexan-1-amine
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CID: 6433106
TTD: D01KMR
DrugBank: DB04926
 Compound Name COL-195 Phase 1/2 [21]
External Link
TTD: D0XB8Y
 Compound Name REL-1028 Phase 1 [21]
External Link
TTD: D0XD0N
 Compound Name CNTX-0290 Phase 1 [21]
External Link
TTD: D0U0CF
 Compound Name Egalet-004 Phase 1 [21]
External Link
TTD: D0R9WD
 Compound Name TRV734 Phase 1 [21]
External Link
TTD: D0OK6F
 Compound Name CA-011 Phase 1 [21]
Synonyms
2-Amino-4-(p-nitrophenyl)thiazole; 4-(4-Nitrophenyl)-1,3-thiazol-2-amine; 2-Amino-4-(4-nitrophenyl)thiazole; 4-(4-Nitrophenyl)-2-thiazolamine; 2-Thiazolamine, 4-(4-nitrophenyl)-; 4-(4-nitrophenyl)thiazol-2-amine; THIAZOLE, 2-AMINO-4-(p-NITROPHENYL)-; 4-(4-Nitrophenyl)thiazol-2-ylamine; 2-amino-4-(4'-nitrophenyl)-1,3-thiazole; RIKJWJIWXCUKQV-UHFFFAOYSA-N; BRN 0200321; 4-(4-Nitro-phenyl)-thiazol-2-ylamine; AI3-62320; 4-(4-nitrophenyl)-1,3-thiazole-2-ylamine; DSSTox_CID_65; AC1L27WX; Cambridge id 5156331; DSSTox_RID_
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CID: 16420
TTD: D0KK9D
 Compound Name PF-06305591 Phase 1 [39]
External Link
CID: 71666749
TTD: D0K9IF
DrugBank: DB12106
 Compound Name OX-27 Phase 1 [40]
External Link
TTD: D0J9GR
 Compound Name DWJ-208 Phase 1 [41]
External Link
TTD: D0G0ER
 Compound Name JNJ-39439335 Phase 1 [42]
Synonyms
Mavatrep; 956274-94-5; UNII-F197218T99; F197218T99; Mavatrep [USAN:INN]; Mavatrep (USAN); JNJ 39439335; SCHEMBL1796599; SCHEMBL1797450; CHEMBL2364618; Mavatrep(JNJ-39439335); DTXSID90241905; BCP23936; EX-A2266; ZINC43175494; BDBM50086717; AKOS030527038; DB12875; CS-4591; SB17026; trans-2-(2-(2-(2-(4-Trifluoromethylphenyl)vinyl)-1H-benzimidazol-5-yl)phenyl)propan-2-ol; BC600772; HY-16935; B5930; J3.561.747G; D10370
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CID: 17751090
TTD: D0EM4S
DrugBank: DB12875
 Compound Name ABT-110 Phase 1 [43]
Synonyms
Hu-alphaD11; PG-110; Humanized anti-NGF antibody (pain), Lay Line Genomics; Humanized anti-NGF antibody (pain), PanGenetics; Humanized anti-nerve growth factor antibody (pain), Lay Line Genomics; Humanized anti-nerve growth factor antibody (pain), PanGenetics
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TTD: D03APM
 Compound Name Debio 0827 Phase 1 [44]
External Link
CID: 16123252
TTD: D02HUY
 Compound Name GDC0310 Phase 1 [21]
Synonyms
RG6029; FCTMRPTVPHVTTN-UHFFFAOYSA-N; SCHEMBL16770884; BDBM71258; BCP25347; US9694002, 346; 1788066-71-6
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External Link
CID: 118120526
TTD: D01FZZ
 Compound Name PF614 Phase 1 [21]
External Link
TTD: D00SBU
 Compound Name ABT-102 Phase 1 [45]
Synonyms
3-(1H-indazol-4-yl)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)urea
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External Link
CID: 11256560
TTD: D00CMV
 Compound Name PMID25666693-Compound-68 Patented [46]
External Link
CID: 23628075
TTD: D0ZZ8F
 Compound Name PMID25666693-Compound-152 Patented [46]
External Link
CID: 44548476
TTD: D0ZS3E
 Compound Name PMID25666693-Compound-96 Patented [46]
External Link
TTD: D0ZQ2W
 Compound Name PMID25666693-Compound-105 Patented [46]
External Link
CID: 25027804
TTD: D0ZP2C
 Compound Name PMID25666693-Compound-18 Patented [46]
External Link
CID: 25265637
TTD: D0ZM8H
 Compound Name Six-membered heterocyclic benzamide derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2015143654Example29
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TTD: D0ZE6H
 Compound Name PMID25666693-Compound-107 Patented [46]
External Link
CID: 51349201
TTD: D0ZE1M
 Compound Name PMID25666693-Compound-144 Patented [46]
External Link
CID: 67412556
TTD: D0Z5HH
 Compound Name PMID25666693-Compound-160 Patented [46]
External Link
TTD: D0Z4QQ
 Compound Name PMID25666693-Compound-151 Patented [46]
External Link
CID: 68324656
TTD: D0YU9B
 Compound Name PMID25666693-Compound-21 Patented [46]
External Link
TTD: D0YR4E
 Compound Name PMID28270021-Compound-WO2014078408Example26 Patented [47]
External Link
TTD: D0YN0I
 Compound Name PMID25666693-Compound-67 Patented [46]
External Link
CID: 23628014
TTD: D0YM1M
 Compound Name PMID25666693-Compound-64 Patented [46]
External Link
TTD: D0Y9ST
 Compound Name PMID25666693-Compound-100 Patented [46]
External Link
CID: 71480662
TTD: D0Y1SI
 Compound Name Azaindazole amide derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2014016434Example30
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External Link
TTD: D0Y1NH
 Compound Name PMID28270021-Compound-WO2013009582Example76 Patented [47]
External Link
TTD: D0Y0XJ
 Compound Name PMID25666693-Compound-161 Patented [46]
External Link
TTD: D0XX8R
 Compound Name N-acylpyrrolidine ether derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2016020784Example11
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External Link
TTD: D0X4LA
 Compound Name PMID25666693-Compound-39 Patented [46]
External Link
CID: 57335613
TTD: D0X1OO
 Compound Name N-acylpiperidine ether derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2015092610Example164
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External Link
TTD: D0X1LP
 Compound Name PMID25666693-Compound-120 Patented [46]
External Link
CID: 53477386
TTD: D0WX4W
 Compound Name PMID25666693-Compound-132 Patented [46]
External Link
CID: 66908117
TTD: D0WT1W
 Compound Name PMID25666693-Compound-91 Patented [46]
External Link
TTD: D0WJ8R
 Compound Name Imidazo pyridine derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2015200341Example96
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External Link
TTD: D0WI7N
 Compound Name PMID25666693-Compound-33 Patented [46]
External Link
CID: 71611619
TTD: D0W4AA
 Compound Name PMID28270021-Compound-WO2015042088Example12 Patented [47]
External Link
TTD: D0VD5J
 Compound Name Pyrazolo[1,5-a]pyridine derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2013088257Example240
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External Link
TTD: D0V9ZJ
 Compound Name PMID25666693-Compound-89 Patented [46]
External Link
TTD: D0V9RM
 Compound Name PMID25666693-Compound-36 Patented [46]
External Link
CID: 71611910
TTD: D0V3PI
 Compound Name Tri-substituted urea derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2013176970Example1
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External Link
TTD: D0UQ2G
 Compound Name Six-membered heterocyclic benzamide derivative 5 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148344Example152
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External Link
TTD: D0UN4M
 Compound Name PMID25666693-Compound-83 Patented [46]
External Link
CID: 11720246
TTD: D0UE9K
 Compound Name PMID25666693-Compound-45 Patented [46]
External Link
CID: 70816331
TTD: D0U8YZ
 Compound Name PMID28270021-Compound-WO2015042088Example11 Patented [47]
External Link
TTD: D0U5XI
 Compound Name PMID25666693-Compound-125 Patented [46]
External Link
CID: 53475699
TTD: D0U5ON
 Compound Name PMID25666693-Compound-54 Patented [46]
External Link
CID: 70816505
TTD: D0U5CQ
 Compound Name Pyrido[3,2-d]pyrimidine derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2012125668Example27
    Click to Show/Hide
External Link
TTD: D0U3RD
 Compound Name PMID25666693-Compound-38 Patented [46]
External Link
CID: 87087836
TTD: D0TZ2W
 Compound Name Five membered heterocyclic benzamide derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148350Example36
    Click to Show/Hide
External Link
TTD: D0T4CF
 Compound Name PMID28270021-Compound-WO2010077680 109 Patented [47]
External Link
TTD: D0T0HM
 Compound Name PMID25666693-Compound-16 Patented [46]
External Link
CID: 46191563
TTD: D0SD4G
 Compound Name Pyrrolo[2,3-d]pyrimidine derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2012137089cE-245677
    Click to Show/Hide
External Link
TTD: D0S0II
 Compound Name Pyrido[3,2-d]pyrimidine derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2012125668Example12
    Click to Show/Hide
External Link
TTD: D0RR8O
 Compound Name Pyrazolo[4,3-c]pyridine derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2014053965Example3
    Click to Show/Hide
External Link
TTD: D0RK6W
 Compound Name PMID25666693-Compound-139 Patented [46]
External Link
TTD: D0RC7L
 Compound Name PMID25666693-Compound-32 Patented [46]
External Link
TTD: D0R9RP
 Compound Name PMID25666693-Compound-14 Patented [46]
External Link
CID: 60202428
TTD: D0R8GA
 Compound Name PMID25666693-Compound-106 Patented [46]
External Link
CID: 51349065
TTD: D0R2VB
 Compound Name PMID25666693-Compound-122 Patented [46]
External Link
CID: 53476470
TTD: D0R2QV
 Compound Name PMID28270021-Compound-WO2014129431Example8-1 Patented [47]
External Link
TTD: D0QT8L
 Compound Name PMID25666693-Compound-81 Patented [46]
External Link
CID: 11706654
TTD: D0QP4N
 Compound Name PMID28270021-Compound-WO2010077680 201 Patented [47]
External Link
TTD: D0PY0G
 Compound Name PMID25666693-Compound-112 Patented [46]
External Link
CID: 70652314
TTD: D0PT0U
 Compound Name PMID25666693-Compound-129 Patented [46]
External Link
TTD: D0PJ8O
 Compound Name PMID25666693-Compound-43 Patented [46]
External Link
TTD: D0P9KJ
 Compound Name Pyrrolo[2,3-b]pyridine derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2008063888P-0171
    Click to Show/Hide
External Link
TTD: D0P8SR
 Compound Name PMID25666693-Compound-49 Patented [46]
External Link
CID: 71238636
TTD: D0P5SB
 Compound Name PMID25666693-Compound-57 Patented [46]
External Link
CID: 71537379
TTD: D0P0MR
 Compound Name PMID25666693-Compound-8 Patented [46]
External Link
CID: 66549082
TTD: D0ON4M
 Compound Name PMID25666693-Compound-75 Patented [46]
External Link
CID: 11598064
TTD: D0OC6A
 Compound Name PMID25666693-Compound-53 Patented [46]
External Link
CID: 70816499
TTD: D0OA1P
 Compound Name PMID25666693-Compound-63 Patented [46]
External Link
CID: 71534837
TTD: D0O9GI
 Compound Name Pyrazolo[4,3-h]quinazoline-3-carboxamide derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2010106028Milciclib (PHA-848125)
    Click to Show/Hide
External Link
TTD: D0O8SX
 Compound Name PMID25666693-Compound-6 Patented [46]
External Link
CID: 66549275
TTD: D0O7IQ
 Compound Name PMID25666693-Compound-92 Patented [46]
External Link
TTD: D0O6VU
 Compound Name PMID25666693-Compound-136 Patented [46]
External Link
CID: 58387639
TTD: D0O3TG
 Compound Name PMID25666693-Compound-86 Patented [46]
External Link
CID: 56949431
TTD: D0O0UG
 Compound Name Bicyclic heteroaryl benzamide derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148354Example41
    Click to Show/Hide
External Link
TTD: D0O0GZ
 Compound Name PMID25666693-Compound-157 Patented [46]
External Link
CID: 52949700
TTD: D0NV2M
 Compound Name PMID25666693-Compound-19 Patented [46]
External Link
CID: 25263543
TTD: D0NM3D
 Compound Name PMID25666693-Compound-142 Patented [46]
External Link
CID: 58387658
TTD: D0NH2M
 Compound Name PMID25666693-Compound-35 Patented [46]
External Link
TTD: D0NB5M
 Compound Name PMID25666693-Compound-7 Patented [46]
External Link
CID: 66551085
TTD: D0N9FJ
 Compound Name Bicyclic heteroaryl benzamide derivative 7 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148373Example36
    Click to Show/Hide
External Link
TTD: D0N6NG
 Compound Name PMID25666693-Compound-24 Patented [46]
External Link
TTD: D0N2UQ
 Compound Name PMID25666693-Compound-156 Patented [46]
External Link
CID: 24783142
TTD: D0N0TF
 Compound Name PMID25666693-Compound-146 Patented [46]
External Link
CID: 59730981
TTD: D0N0QN
 Compound Name Triazolo[4,3-b]pyridazine derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2012125667Example24
    Click to Show/Hide
External Link
TTD: D0MZ7K
 Compound Name PMID25666693-Compound-109 Patented [46]
External Link
CID: 11187857
TTD: D0MY3K
 Compound Name PMID25666693-Compound-47 Patented [46]
External Link
CID: 88995251
TTD: D0MU3S
 Compound Name PMID28270021-Compound-WO2015042088Example4 Patented [47]
External Link
TTD: D0M8VS
 Compound Name PMID25666693-Compound-29 Patented [46]
External Link
CID: 71599906
TTD: D0M4WY
 Compound Name PMID28270021-Compound-WO2016054807Example112 Patented [47]
External Link
TTD: D0LK8E
 Compound Name PMID25666693-Compound-162 Patented [46]
External Link
TTD: D0LA0Q
 Compound Name PMID25666693-Compound-137 Patented [46]
External Link
TTD: D0KM0W
 Compound Name PMID25666693-Compound-98 Patented [46]
External Link
CID: 71480662
TTD: D0KF3A
 Compound Name Bicyclic heteroaryl benzamide derivative 5 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148373Example104
    Click to Show/Hide
External Link
TTD: D0KC8X
 Compound Name PMID25666693-Compound-1 Patented [46]
External Link
CID: 68313317
TTD: D0KB2Z
 Compound Name PMID28270021-Compound-WO2010077680 495 Patented [47]
External Link
TTD: D0K6IM
 Compound Name PMID25666693-Compound-46 Patented [46]
External Link
TTD: D0K4SZ
 Compound Name PMID25666693-Compound-148 Patented [46]
External Link
CID: 59731038
TTD: D0K3KM
 Compound Name PMID25666693-Compound-155 Patented [46]
External Link
CID: 24782891
TTD: D0K3KE
 Compound Name PMID25666693-Compound-141 Patented [46]
External Link
CID: 53402973
TTD: D0K0ZI
 Compound Name PMID25666693-Compound-62 Patented [46]
External Link
CID: 71506872
TTD: D0JX4I
 Compound Name PMID25666693-Compound-147 Patented [46]
External Link
CID: 59731029
TTD: D0JT8B
 Compound Name PMID25666693-Compound-22 Patented [46]
External Link
TTD: D0JK2N
 Compound Name PMID25666693-Compound-31 Patented [46]
External Link
TTD: D0JC8L
 Compound Name PMID25666693-Compound-59 Patented [46]
External Link
CID: 71539690
TTD: D0J9CS
 Compound Name PMID28270021-Compound-WO2010077680 103 Patented [47]
External Link
TTD: D0J4CA
 Compound Name PMID25666693-Compound-52 Patented [46]
External Link
CID: 70816169
TTD: D0IU1H
 Compound Name PMID25666693-Compound-94 Patented [46]
External Link
TTD: D0IT4N
 Compound Name PMID25666693-Compound-27 Patented [46]
External Link
CID: 71599827
TTD: D0IR7H
 Compound Name PMID25666693-Compound-9 Patented [46]
External Link
CID: 66549271
TTD: D0IP5E
 Compound Name PMID25666693-Compound-48 Patented [46]
External Link
TTD: D0IN5E
 Compound Name PMID25666693-Compound-102 Patented [46]
External Link
TTD: D0IK1S
 Compound Name Bicyclic heteroaryl benzamide derivative 4 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148354Example99
    Click to Show/Hide
External Link
TTD: D0I9FU
 Compound Name PMID25666693-Compound-159 Patented [46]
External Link
TTD: D0I3ZW
 Compound Name PMID28270021-Compound-WO2013161919Example85-117 Patented [47]
External Link
TTD: D0I2OO
 Compound Name PMID25666693-Compound-20 Patented [46]
External Link
TTD: D0HS1D
 Compound Name Bicyclic heteroaryl benzamide derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148354Example21(R or S)
    Click to Show/Hide
External Link
TTD: D0HF1A
 Compound Name PMID25666693-Compound-11 Patented [46]
External Link
CID: 66549650
TTD: D0HE7X
 Compound Name PMID25666693-Compound-72 Patented [46]
External Link
CID: 11582721
TTD: D0H6CX
 Compound Name PMID25666693-Compound-80 Patented [46]
External Link
CID: 11656215
TTD: D0H4TR
 Compound Name Six-membered heterocyclic benzamide derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2015143654Example41
    Click to Show/Hide
External Link
TTD: D0H3ZG
 Compound Name PMID25666693-Compound-4 Patented [46]
External Link
CID: 66551282
TTD: D0GZ4G
 Compound Name PMID25666693-Compound-66 Patented [46]
External Link
CID: 23627957
TTD: D0GV5G
 Compound Name PMID25666693-Compound-143 Patented [46]
External Link
TTD: D0G6IQ
 Compound Name PMID25666693-Compound-55 Patented [46]
External Link
CID: 56836246
TTD: D0G3UV
 Compound Name PMID28270021-Compound-WO2010077680 481 Patented [47]
External Link
TTD: D0FL8A
 Compound Name Bicyclic heteroaryl benzamide derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148354Example33(R or S)
    Click to Show/Hide
External Link
TTD: D0F8BF
 Compound Name PMID25666693-Compound-65 Patented [46]
External Link
CID: 71238361
TTD: D0F5NQ
 Compound Name PMID25666693-Compound-15 Patented [46]
External Link
CID: 25263680
TTD: D0F4YX
 Compound Name PMID25666693-Compound-30 Patented [46]
External Link
CID: 71598766
TTD: D0F4DI
 Compound Name PMID25666693-Compound-101 Patented [46]
External Link
CID: 71609207
TTD: D0F3HP
 Compound Name PMID28270021-Compound-WO2010077680 803 Patented [47]
External Link
TTD: D0F2BF
 Compound Name PMID25666693-Compound-26 Patented [46]
External Link
CID: 71599484
TTD: D0EV3G
 Compound Name PMID25666693-Compound-118 Patented [46]
External Link
CID: 53386424
TTD: D0EH2T
 Compound Name Six-membered heterocyclic benzamide derivative 4 Patented [47]
Synonyms
PMID28270021-Compound-WO2015143654Example62
    Click to Show/Hide
External Link
TTD: D0EC4Z
 Compound Name PMID25666693-Compound-82 Patented [46]
External Link
TTD: D0EC3Z
 Compound Name PMID25666693-Compound-69 Patented [46]
External Link
CID: 23628077
TTD: D0E8UP
 Compound Name PMID25666693-Compound-110 Patented [46]
External Link
TTD: D0E0SA
 Compound Name Bicyclic heteroaryl benzamide derivative 8 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148373Example41(S)
    Click to Show/Hide
External Link
TTD: D0DY5R
 Compound Name PMID25666693-Compound-124 Patented [46]
External Link
CID: 53476472
TTD: D0DT7M
 Compound Name Pyrrolo[3,2-c]pyridine derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2014053968Example5
    Click to Show/Hide
External Link
TTD: D0DQ5G
 Compound Name Pyrazolo[1,5-a]pyridine derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2013088256Example59
    Click to Show/Hide
External Link
TTD: D0DN3Q
 Compound Name PMID25666693-Compound-130 Patented [46]
External Link
TTD: D0DI1R
 Compound Name PMID25666693-Compound-42 Patented [46]
External Link
CID: 70816270
TTD: D0DE5K
 Compound Name PMID25666693-Compound-78 Patented [46]
External Link
TTD: D0DE5I
 Compound Name PMID25666693-Compound-74 Patented [46]
External Link
CID: 11676921
TTD: D0DC4O
 Compound Name PMID25666693-Compound-108 Patented [46]
External Link
CID: 51349341
TTD: D0D4NX
 Compound Name PMID25666693-Compound-115 Patented [46]
External Link
CID: 88875843
TTD: D0D2CF
 Compound Name Five membered heterocyclic benzamide derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148350Example81
    Click to Show/Hide
External Link
TTD: D0CY3U
 Compound Name PMID25666693-Compound-76 Patented [46]
External Link
CID: 11532887
TTD: D0CX4C
 Compound Name PMID25666693-Compound-138 Patented [46]
External Link
TTD: D0CR0H
 Compound Name Tri-substituted urea derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2013176970Example2
    Click to Show/Hide
External Link
TTD: D0CG8N
 Compound Name PMID25666693-Compound-87 Patented [46]
External Link
CID: 56961050
TTD: D0C9FN
 Compound Name PMID25666693-Compound-12 Patented [46]
External Link
CID: 66549652
TTD: D0C8ZZ
 Compound Name PMID25666693-Compound-114 Patented [46]
External Link
CID: 89556774
TTD: D0C5NT
 Compound Name N-(phenylpyrazolyl)benzamide derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2013132376Example157
    Click to Show/Hide
External Link
TTD: D0C3RK
 Compound Name PMID25666693-Compound-10 Patented [46]
External Link
CID: 66551086
TTD: D0C1MZ
 Compound Name PMID28270021-Compound-WO2016054807Example80 Patented [47]
External Link
TTD: D0BO1H
 Compound Name PMID25666693-Compound-77 Patented [46]
External Link
CID: 11562798
TTD: D0B4NI
 Compound Name PMID25666693-Compound-51 Patented [46]
External Link
CID: 57335038
TTD: D0B0WJ
 Compound Name 3-amino-5-benzyl-substituted indazole derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2010106028Entrectinib (RXDX-101)
    Click to Show/Hide
External Link
TTD: D0AU4G
 Compound Name PMID25666693-Compound-153 Patented [46]
External Link
CID: 88937082
TTD: D0AQ3U
 Compound Name Pyrrolo[2,3-d]pyrimidine derivative 4 Patented [47]
Synonyms
PMID28270021-Compound-WO2012137089PF-06278121 (Example 9)
    Click to Show/Hide
External Link
TTD: D0AG2A
 Compound Name PMID25666693-Compound-113 Patented [46]
External Link
CID: 70652315
TTD: D0A8LU
 Compound Name PMID25666693-Compound-25 Patented [46]
External Link
CID: 71599909
TTD: D0A3XC
 Compound Name PMID25666693-Compound-34 Patented [46]
External Link
CID: 71611907
TTD: D0A0YI
 Compound Name PMID25666693-Compound-40 Patented [46]
External Link
CID: 66644325
TTD: D09ZWU
 Compound Name PMID25666693-Compound-128 Patented [46]
External Link
CID: 24758063
TTD: D09SMA
 Compound Name PMID25666693-Compound-79 Patented [46]
External Link
CID: 11677423
TTD: D09QXC
 Compound Name PMID25666693-Compound-84 Patented [46]
External Link
CID: 11613881
TTD: D08ZBB
 Compound Name PMID25666693-Compound-111 Patented [46]
External Link
TTD: D08YAL
 Compound Name PMID25666693-Compound-135 Patented [46]
External Link
CID: 58387673
TTD: D08UEC
 Compound Name PMID25666693-Compound-13 Patented [46]
External Link
CID: 66549649
TTD: D08ICT
 Compound Name PMID28270021-Compound-WO2016054807Example71 Patented [47]
External Link
TTD: D08CZY
 Compound Name PMID25666693-Compound-123 Patented [46]
External Link
CID: 53476471
TTD: D08CLA
 Compound Name N-acylpyrrolidine ether derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2016020784Example12
    Click to Show/Hide
External Link
TTD: D08BIH
 Compound Name PMID25666693-Compound-134 Patented [46]
External Link
CID: 11674039
TTD: D07XZR
 Compound Name PMID25666693-Compound-119 Patented [46]
External Link
CID: 53477385
TTD: D07XVL
 Compound Name Six-membered heterocyclic benzamide derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2015143654Example60
    Click to Show/Hide
External Link
TTD: D07VFQ
 Compound Name PMID25666693-Compound-131 Patented [46]
External Link
CID: 25094155
TTD: D07RYM
 Compound Name PMID25666693-Compound-127 Patented [46]
External Link
CID: 24759759
TTD: D07MNI
 Compound Name PMID28270021-Compound-WO2010077680 811 Patented [47]
External Link
TTD: D07KVL
 Compound Name PMID25666693-Compound-17 Patented [46]
External Link
TTD: D07JNJ
 Compound Name PMID25666693-Compound-117 Patented [46]
External Link
TTD: D07FWF
 Compound Name PMID25666693-Compound-50 Patented [46]
External Link
CID: 71237925
TTD: D07FIY
 Compound Name PMID25666693-Compound-56 Patented [46]
External Link
CID: 71238385
TTD: D07EGF
 Compound Name PMID25666693-Compound-41 Patented [46]
External Link
CID: 66644203
TTD: D07EAV
 Compound Name Bicyclic heteroaryl benzamide derivative 6 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148373Example111
    Click to Show/Hide
External Link
TTD: D07CPL
 Compound Name PMID25666693-Compound-85 Patented [46]
External Link
CID: 11671115
TTD: D07BZW
 Compound Name Bicyclic heteroaryl benzamide derivative 9 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148373Example42(R)
    Click to Show/Hide
External Link
TTD: D07AJO
 Compound Name PMID27998201-Compound-12 Patented [48]
External Link
TTD: D06XCD
 Compound Name PMID25666693-Compound-3 Patented [46]
External Link
CID: 66549466
TTD: D06VYF
 Compound Name PMID25666693-Compound-37 Patented [46]
External Link
CID: 49802515
TTD: D06JHW
 Compound Name Pyrrolo[2,3-b]pyridine derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2008063888P-0180
    Click to Show/Hide
External Link
TTD: D06GOT
 Compound Name PMID25666693-Compound-90 Patented [46]
External Link
TTD: D05ZWR
 Compound Name PMID25666693-Compound-28 Patented [46]
External Link
CID: 71580510
TTD: D05SWL
 Compound Name PMID25666693-Compound-116 Patented [46]
External Link
CID: 88875796
TTD: D05SMP
 Compound Name PMID25666693-Compound-99 Patented [46]
External Link
CID: 71498842
TTD: D05RBF
 Compound Name Six-membered heterocyclic benzamide derivative 7 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148344Example96
    Click to Show/Hide
External Link
TTD: D05MRY
 Compound Name PMID28270021-Compound-WO2014078408Example1 Patented [47]
External Link
TTD: D05AQT
 Compound Name PMID25666693-Compound-154 Patented [46]
External Link
CID: 88937150
TTD: D04TIU
 Compound Name N-acylpiperidine ether derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2015092610Example114
    Click to Show/Hide
External Link
TTD: D04RXX
 Compound Name Six-membered heterocyclic benzamide derivative 6 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148344Example59
    Click to Show/Hide
External Link
TTD: D04JCD
 Compound Name PMID25666693-Compound-93 Patented [46]
External Link
TTD: D04HCS
 Compound Name N-acylpiperidine ether derivative 6 Patented [47]
Synonyms
PMID28270021-Compound-WO2015092610Example9
    Click to Show/Hide
External Link
TTD: D04GCC
 Compound Name PMID25666693-Compound-44 Patented [46]
External Link
CID: 70816274
TTD: D04FRL
 Compound Name Five membered heterocyclic benzamide derivative 2 Patented [47]
Synonyms
PMID28270021-Compound-WO2015148350Example76
    Click to Show/Hide
External Link
TTD: D04BRW
 Compound Name PMID25666693-Compound-97 Patented [46]
External Link
TTD: D03ZOZ
 Compound Name PMID25666693-Compound-71 Patented [46]
External Link
CID: 23628017
TTD: D03YFL
 Compound Name PMID25666693-Compound-145 Patented [46]
External Link
CID: 67412506
TTD: D03VXP
 Compound Name PMID25666693-Compound-88 Patented [46]
External Link
TTD: D03SHM
 Compound Name PMID25666693-Compound-61 Patented [46]
External Link
TTD: D03QAW
 Compound Name PMID25666693-Compound-73 Patented [46]
External Link
CID: 11532940
TTD: D03FSF
 Compound Name PMID25666693-Compound-70 Patented [46]
External Link
CID: 58416270
TTD: D03EEA
 Compound Name N-acylpiperidine ether derivative 5 Patented [47]
Synonyms
PMID28270021-Compound-WO2015092610Example3
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External Link
TTD: D03BAY
 Compound Name PMID28270021-Compound-WO2013009582Example16 Patented [47]
External Link
TTD: D02ZQN
 Compound Name PMID25666693-Compound-23 Patented [46]
External Link
TTD: D02QJE
 Compound Name N-acylpiperidine ether derivative 7 Patented [47]
Synonyms
PMID28270021-Compound-WO2016009296Example15
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External Link
TTD: D02OLJ
 Compound Name PMID25666693-Compound-5 Patented [46]
External Link
TTD: D02OAH
 Compound Name PMID25666693-Compound-140 Patented [46]
External Link
CID: 23585453
TTD: D02JQB
 Compound Name Pyrrolo[2,3-b]pyridine derivative 3 Patented [47]
Synonyms
PMID28270021-Compound-WO2010129570P-2061
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External Link
TTD: D02IBX
 Compound Name PMID28270021-Compound-WO2014152663 701 Patented [47]
External Link
TTD: D02ETU
 Compound Name PMID25666693-Compound-126 Patented [46]
External Link
CID: 53475700
TTD: D02EKO
 Compound Name PMID25666693-Compound-104 Patented [46]
External Link
CID: 25104368
TTD: D01RUK
 Compound Name PMID25666693-Compound-58 Patented [46]
External Link
TTD: D01PLJ
 Compound Name PMID25666693-Compound-103 Patented [46]
External Link
TTD: D01LGQ
 Compound Name PMID25666693-Compound-158 Patented [46]
External Link
CID: 16742146
TTD: D01HED
 Compound Name PMID25666693-Compound-133 Patented [46]
External Link
CID: 25094231
TTD: D01GEK
 Compound Name PMID25666693-Compound-150 Patented [46]
External Link
CID: 68324561
TTD: D01DNH
 Compound Name PMID25666693-Compound-2 Patented [46]
External Link
CID: 66549276
TTD: D00YXA
 Compound Name N-acylpiperidine ether derivative 1 Patented [47]
Synonyms
PMID28270021-Compound-WO2015092610Example113
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External Link
TTD: D00XXZ
 Compound Name PMID25666693-Compound-60 Patented [46]
External Link
TTD: D00QEZ
 Compound Name PMID25666693-Compound-149 Patented [46]
External Link
TTD: D00OLY
 Compound Name PMID25666693-Compound-95 Patented [46]
External Link
TTD: D00ODY
 Compound Name PMID28270021-Compound-WO2016054807Example1 Patented [47]
External Link
TTD: D00MGO
 Compound Name PMID25666693-Compound-121 Patented [46]
External Link
CID: 53477387
TTD: D00KTN
 Compound Name N-acylpiperidine ether derivative 4 Patented [47]
Synonyms
PMID28270021-Compound-WO2015092610Example2
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External Link
TTD: D00FJH
 Compound Name PMID28270021-Compound-WO2016054807Example82 Patented [47]
External Link
TTD: D00EUL
 Compound Name Propiram fumarate Discontinued in Phase 3 [49]
Synonyms
Algeril; Diramax; Dirame; Diramine; Diratab; Propiram; FBA-4503
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External Link
CID: 6433584
TTD: D08LIF
 Compound Name AMG-517 Discontinued in Phase 1 [50]
Synonyms
AMG 517; BD-0082
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External Link
CID: 16007367
TTD: D0L5XI
 Compound Name BL-1827 Discontinued in Phase 1 [51]
External Link
TTD: D06MXY
 Compound Name SequestOx Application submitted [21]
Synonyms
Oxycodone / naltrexone; Naltrexone / oxycodone; Troxyca Er; Oxycodone hydrochloride / naltrexone hydrochloride; Naltrexone hydrochloride / oxycodone hydrochloride; Naltrexone hydrochloride and oxycodone hydrochloride; ALO-02; Naltrexone hydrochloride mixture with oxycodone hydrochloride; 850636-71-4; Oxycodone hydrochloride and naltrexone hydrochloride
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External Link
CID: 90479726
TTD: D0FU5Y
 Compound Name Remoxy ER Application submitted [21]
External Link
TTD: D0B7VH
 Compound Name Oxycodone hydrochloride Application submitted [21]
Synonyms
oxycodone ER
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External Link
CID: 5462350
TTD: D07WPQ
 Compound Name DBO-17 Terminated [52]
External Link
CID: 10042211
TTD: D0XH1H
 Compound Name DBO-11 Terminated [53]
Synonyms
166374-49-8; Naxifylline (USAN/INN)
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External Link
CID: 23724971
TTD: D0PE1A
 Compound Name ACEA-1328 Terminated [54]
External Link
CID: 9816093
TTD: D0O4JH
 Compound Name RO-25-6981 Terminated [55]
Synonyms
Ro 25-6981; CHEMBL305195; ro25-6981; 169274-78-6; 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol; 4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl)phenol; QEM; Tocris-1594; AC1O7H0A; Lopac0_001082; ZINC7042; SCHEMBL6159263; CHEBI:92897; HMS3268G13; EX-A1825; PDSP2_000361; BDBM50080029; CS-2011; CCG-205159; NCGC00025226-01; NCGC00025226-03; NCGC00025226-02; HY-13993; (AR,BS)-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL MALEATE; BRD-K51541829-001-01-3
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External Link
CID: 6604887
TTD: D0K0DB
 Compound Name THA-901 Investigative [56]
Synonyms
TH-901
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External Link
TTD: D06MEC
 Compound Name SP-SAP Investigative [57]
Synonyms
NK1-saporin conjugate, Advanced Targeting Systems; Neurokinin NK1-saporin conjugate, ATS; SP-SAP, APT; SP-SAP, Advanced Pain Therapeutics; SP-SAP, Advanced Targeting Systems; Substance P-saporin conjugate, ATS; Substance P-saporin conjugate, Advanced Targeting Systems
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External Link
TTD: D04LHG
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