General Information of the m6A Target Gene (ID: M6ATAR00602)
Target Name Lnc_STAT3
Gene Name Lnc_STAT3
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
Lnc_STAT3 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Parkinson disease [ICD-11: 8A00]
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary Paraquat (PQ) is a ubiquitously applied herbicide. Long-term PQ exposure with low dose has been reported to induce abnormal expression of long non-coding RNAs (lncRNAs) in brain nerve cells, which could further lead to Parkinson's disease (PD). Tow specific m6A modified lncRNAs were identified: lncRNA CDC5L and Lnc_STAT3, which could influence downstream autophagy related biological function.
Responsed Disease Parkinson disease [ICD-11: 8A00]
Pathway Response Autophagy hsa04140
Cell Process Cell autophagy
In-vitro Model ()