General Information of the m6A Target Gene (ID: M6ATAR00557)
Target Name Non-metastatic gene A protein (BAMBI)
Synonyms
Non-metastatic gene A protein; Putative transmembrane protein NMA
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Gene Name BAMBI
Chromosomal Location 10p12.1
Family BAMBI family
Function
Negatively regulates TGF-beta signaling.
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Gene ID 25805
Uniprot ID
BAMBI_HUMAN
HGNC ID
HGNC:30251
Ensembl Gene ID
ENSG00000095739
KEGG ID
hsa:25805
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
BAMBI can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Gestational diabetes mellitus [ICD-11: JA63]
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary Down-regulation of m6A both in the 3'-UTR and CDS near stop codons of placental mRNAs is involved in gestational diabetes mellitus(GDM) development in Han Chinese women. MazF-qPCR verified that the m6A levels of the Non-metastatic gene A protein (BAMBI) 3'-UTR and CDS were significantly decreased in GDM. m6A levels of GDM related genes (INSR and IRS1) were significantly reduced in GDM.
Responsed Disease Gestational diabetes mellitus [ICD-11: JA63]