m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00494)
Target Name Splicing factor 3A subunit 3 (SF3A3)
Synonyms
SF3a60; Spliceosome-associated protein 61; SAP 61
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Gene Name SF3A3
Chromosomal Location 1p34.3
Family SF3A3 family
Function
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.
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Gene ID 10946
Uniprot ID
SF3A3_HUMAN
HGNC ID
HGNC:10767
Ensembl Gene ID
ENSG00000183431
KEGG ID
hsa:10946
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
SF3A3 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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YTH domain-containing family protein 2 (YTHDF2) [READER]
 Regulator Info 
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary YTHDF2 expression was associated positively with Splicing factor 3A subunit 3 (SF3A3) expression, which implied that they cooperate in LIHC progression.
Target Regulation Up regulation
Responsed Disease Hepatocellular carcinoma ICD-11: 2C12.02
 Disease Info 
Cell Process Immunity
Liver cancer [ICD-11: 2C12]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary YTHDF2 expression was associated positively with Splicing factor 3A subunit 3 (SF3A3) expression, which implied that they cooperate in LIHC progression.
Responsed Disease Hepatocellular carcinoma [ICD-11: 2C12.02]
Target Regulator YTH domain-containing family protein 2 (YTHDF2) READER
 Regulator Info 
Target Regulation Up regulation
Cell Process Immunity
References
Ref 1 Systematic Analyses of the Role of the Reader Protein of N (6)-Methyladenosine RNA Methylation, YTH Domain Family 2, in Liver Hepatocellular Carcinoma. Front Mol Biosci. 2020 Dec 2;7:577460. doi: 10.3389/fmolb.2020.577460. eCollection 2020.