m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00400)
Target Name Staphylococcal nuclease domain-containing protein 1 (SND1)
Synonyms
100 kDa coactivator; EBNA2 coactivator p100; Tudor domain-containing protein 11; p100 co-activator; TDRD11
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Gene Name SND1
Chromosomal Location 7q32.1
Function
Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5 (By similarity).; (Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).
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Gene ID 27044
Uniprot ID
SND1_HUMAN
HGNC ID
HGNC:30646
Ensembl Gene ID
ENSG00000197157
KEGG ID
hsa:27044
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
SND1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Kaposi's sarcoma [ICD-11: 2B57]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary Staphylococcal nuclease domain-containing protein 1 (SND1) depletion leads to inhibition of KSHV early gene expression showing that SND1 is essential for Kaposi's sarcoma associated herpesvirus(KSHV) lytic replication.
Responsed Disease Kaposi's sarcoma [ICD-11: 2B57]
In-vitro Model ()
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Colorectal cancer [ICD-11: 2B91]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary The colorimetric m6A quantification strategy revealed that Staphylococcal nuclease domain-containing protein 1 (SND1) could alter m6A levels in colorectal cancer cell lines.
Responsed Disease Colorectal cancer [ICD-11: 2B91]
Cell Process RNA stability
In-vitro Model ()
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