General Information of the m6A Target Gene (ID: M6ATAR00081)
Target Name Long intergenic non-protein coding RNA 1320 (LINC01320)
Synonyms
LINC01320
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Gene Name LINC01320
Chromosomal Location 2p22.3
Family Long intergenic non-protein coding RNAs
Gene ID 104355288
HGNC ID
HGNC:50526
Ensembl Gene ID
ENSG00000228262
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
LINC01320 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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Methyltransferase-like 14 (METTL14) [WRITER]
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary In gastric cancer, METTL14 was involved in the m6A modification of LINC01320 and induced the up-regulation of Long intergenic non-protein coding RNA 1320 (LINC01320).
Target Regulation Up regulation
Responsed Disease Gastric cancer ICD-11: 2B72
Cell Process Cell proliferation
Cell migration
Cell invasion
In-vitro Model AGS Gastric adenocarcinoma Homo sapiens CVCL_0139
GES-1 Normal Homo sapiens CVCL_EQ22
HGC-27 Gastric carcinoma Homo sapiens CVCL_1279
MKN7 Gastric tubular adenocarcinoma Homo sapiens CVCL_1417
MKN45 Gastric adenocarcinoma Homo sapiens CVCL_0434
NCI-N87 Gastric tubular adenocarcinoma Homo sapiens CVCL_1603
Gastric cancer [ICD-11: 2B72]
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary In gastric cancer, METTL14 was involved in the m6A modification of LINC01320 and induced the up-regulation of Long intergenic non-protein coding RNA 1320 (LINC01320).
Responsed Disease Gastric cancer [ICD-11: 2B72]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
Target Regulation Up regulation
Cell Process Cell proliferation
Cell migration
Cell invasion
In-vitro Model AGS Gastric adenocarcinoma Homo sapiens CVCL_0139
GES-1 Normal Homo sapiens CVCL_EQ22
HGC-27 Gastric carcinoma Homo sapiens CVCL_1279
MKN7 Gastric tubular adenocarcinoma Homo sapiens CVCL_1417
MKN45 Gastric adenocarcinoma Homo sapiens CVCL_0434
NCI-N87 Gastric tubular adenocarcinoma Homo sapiens CVCL_1603
References
Ref 1 N6-methyladenosine (m6A)-mediated up-regulation of long noncoding RNA LINC01320 promotes the proliferation, migration, and invasion of gastric cancer via miR495-5p/RAB19 axis. Bioengineered. 2021 Dec;12(1):4081-4091. doi: 10.1080/21655979.2021.1953210.