m6A Target Gene Information
General Information of the m6A Target Gene (ID: M6ATAR00070)
Target Name | hsa_circ_0081609 (circCUX1) | ||||
---|---|---|---|---|---|
Synonyms |
hsa-circ-0081609
Click to Show/Hide
|
||||
Gene Name | hsa_circ_0081609 |
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
hsa_circ_0081609
can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Regulator
Browse Disease
Methyltransferase-like 3 (METTL3) [WRITER]
In total 1 item(s) under this regulator | ||||
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene | [1] | |||
Response Summary | METTL3-mediated m6A modification plays a key role in stabilizing the expression of hsa_circ_0081609 (circCUX1), thereby inhibiting the expression of caspase 1 and conferring the radiotherapy resistance of hypopharyngeal squamous cell carcinoma. | |||
Target Regulation | Up regulation | |||
Responsed Disease | Hypopharyngeal squamous cell carcinoma | ICD-11: 2B6D.0 | ||
In-vitro Model | CLA-27 cell line (The head and neck tumor cell lines) | |||
HOK | Normal | Hexagrammos otakii | CVCL_YE19 | |
SAS | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1675 | |
SCC-15 | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1681 | |
SCC-4 | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1684 | |
SCC-9 | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1685 | |
Tca8113 | Endocervical adenocarcinoma | Homo sapiens | CVCL_6851 | |
Hypopharyngeal cancer [ICD-11: 2B6D]
In total 1 item(s) under this disease | ||||
Experiment 1 Reporting the m6A-centered Disease Response | [1] | |||
Response Summary | METTL3-mediated m6A modification plays a key role in stabilizing the expression of hsa_circ_0081609 (circCUX1), thereby inhibiting the expression of caspase 1 and conferring the radiotherapy resistance of hypopharyngeal squamous cell carcinoma. | |||
Responsed Disease | Hypopharyngeal squamous cell carcinoma [ICD-11: 2B6D.0] | |||
Target Regulator | Methyltransferase-like 3 (METTL3) | WRITER | ||
Target Regulation | Up regulation | |||
In-vitro Model | CLA-27 cell line (The head and neck tumor cell lines) | |||
HOK | Normal | Hexagrammos otakii | CVCL_YE19 | |
SAS | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1675 | |
SCC-15 | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1681 | |
SCC-4 | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1684 | |
SCC-9 | Tongue squamous cell carcinoma | Homo sapiens | CVCL_1685 | |
Tca8113 | Endocervical adenocarcinoma | Homo sapiens | CVCL_6851 | |