m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00053)
Target Name Circ_YTHDC2
Synonyms
Circ-YTHDC2
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Gene Name Circ_YTHDC2
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
Circ_YTHDC2 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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YTH domain-containing protein 2 (YTHDC2) [READER]
 Regulator Info 
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary YTHDC2/Circ_YTHDC2/TET2 pathway is an important target of metformin in preventing the progression of VSMCs dysfunction under high glucose.
Target Regulation Up regulation
Responsed Disease Hematological disorders ICD-11: 3C0Z
 Disease Info 
In-vitro Model A7r5 Normal Rattus norvegicus CVCL_0137
Hematological disorders [ICD-11: 3C0Z]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary YTHDC2/Circ_YTHDC2/TET2 pathway is an important target of metformin in preventing the progression of VSMCs dysfunction under high glucose.
Responsed Disease Hematological disorders [ICD-11: 3C0Z]
Target Regulator YTH domain-containing protein 2 (YTHDC2) READER
 Regulator Info 
Target Regulation Up regulation
In-vitro Model A7r5 Normal Rattus norvegicus CVCL_0137
References
Ref 1 YTHDC2-Mediated circYTHDC2 N6-Methyladenosine Modification Promotes Vascular Smooth Muscle Cells Dysfunction Through Inhibiting Ten-Eleven Translocation 2. Front Cardiovasc Med. 2021 Oct 1;8:686293. doi: 10.3389/fcvm.2021.686293. eCollection 2021.